O[C@@H]1[C@H](O)CS[C@H]1n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc21 CHEMBL413686 Ki 0.00483 nM
O[C@@H]1[C@H](O)CS[C@H]1n1cnc2c(NCc3cccc(Cl)c3)nc(Cl)nc21 CHEMBL387921 Ki 0.0102 nM
CC[C@H](COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL390005 EC50 0.03 nM
Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL38943 Ki 0.048 nM
CCC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL230063 EC50 0.06 nM
CNC(=O)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL200732 Ki 0.16 nM
CCCc1c(OCCCCOc2cccc(CC(=O)O)c2)ccc2c(-c3ccccc3)noc12 CHEMBL435523 Ki 0.3 nM
C/C(=C\COc1ccccc1Cn1c(C)cnc1-c1ccc(OC(F)(F)F)cc1)CCC(=O)O CHEMBL4755323 EC50 0.3 nM
Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OCC(=O)O CHEMBL38508 Kd 0.4 nM
Cc1cnc(-c2ccc(OC(F)(F)F)cc2)n1Cc1ccccc1OCCC[C@@H](C)CC(=O)O CHEMBL4649683 EC50 0.4 nM
Cc1cc(CN2C(=O)CN(c3ccc(C(F)(F)F)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5417169 EC50 0.4 nM
CNC(=O)[C@H]1O[C@@H](n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL431733 Ki 0.43 nM
Cc1cc(CN2Cc3ccccc3C[C@@H]2C(=O)Nc2ccc(Cl)cc2Cl)ccc1OCC(=O)O CHEMBL1643201 EC50 0.5 nM
COc1cc(-c2nccs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220124 EC50 0.58 nM
O=C(O)COc1ccc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2OCC#CCCO)c2c1CCCC2 CHEMBL499312 Ki 0.6 nM
O[C@@H]1[C@H](O)CS[C@H]1n1cnc2c(NCc3ccccc3Cl)nc(Cl)nc21 CHEMBL227279 Ki 0.62 nM
Cc1cc(S[C@H](Cc2ccccc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)ccc1OCC(=O)O CHEMBL4249571 EC50 0.7 nM
C[C@H](CCCOc1ccccc1Cn1c(C(F)(F)F)cnc1-c1ccc(-c2ccco2)cc1)CC(=O)O CHEMBL4635689 EC50 0.7 nM
Cc1cnc(-c2ccc(-c3ccco3)cc2)n1Cc1ccccc1OCCCCCC(=O)O CHEMBL4640515 EC50 0.7 nM
CCCCOc1ccc(C[C@H](CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL375471 EC50 0.72 nM
Cc1cnc(-c2ccc(Cl)c(F)c2)n1Cc1ccccc1OCCC[C@@H](C)CC(=O)O CHEMBL4739884 EC50 0.8 nM
Cc1cc(CN2C(=O)CN(c3ccc(C(F)(F)F)c(F)c3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5395441 EC50 0.8 nM
Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL1169827 EC50 0.9 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4ccc(C(F)(F)F)cn4)cc3)ccc21 CHEMBL220570 EC50 0.95 nM
CC(C)N(Cc1cccc2c1OC(C)(C)C=C2)C(=O)c1ccc(-c2ccccc2)cc1 CHEMBL193426 EC50 1.0 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(C(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O CHEMBL213315 EC50 1.0 nM
CCc1cc(Oc2cc(F)cc([C@@H](C)NC(=O)c3c(C)c4cc(Cl)ccc4n3C)c2)ccc1CCC(=O)O CHEMBL238357 EC50 1.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1 CHEMBL212911 EC50 1.0 nM
Cc1cc(OCc2nc(-c3ccc(C(=O)N(C)C(C)C)cc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1075732 EC50 1.0 nM
Cc1cc(OCc2nc(-c3cnc(OC(C)C)nc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1080365 EC50 1.0 nM
Cc1cc(OCc2nc(-c3cnc(N4CCOCC4)nc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1075895 EC50 1.0 nM
Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OCC(=O)O CHEMBL1630383 EC50 1.0 nM
CCCC(Sc1ccc(OCC(=O)O)c(C)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C CHEMBL2035069 EC50 1.0 nM
Cc1cc(SCc2cnc(-c3ccc(C(F)(F)F)c(F)c3)s2)ccc1OCC(=O)O CHEMBL3786533 EC50 1.0 nM
C/C(=C\COc1ccccc1Cn1c(C)cnc1-c1ccc(-c2ccco2)cc1)CCC(=O)O CHEMBL4743546 EC50 1.0 nM
Cc1cc(N2CC(=O)N(Cc3cc(C)c(OC(C)(C)C(=O)O)c(C)c3)C2=O)ccc1OC(F)(F)F CHEMBL5401474 EC50 1.0 nM
Cc1cc(SC(CC(C)C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035071 EC50 1.1 nM
Cc1cc(SC(CC2CC2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035057 EC50 1.1 nM
Cc1cc(SCc2cnc(-c3ccc(C(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL3786754 EC50 1.1 nM
CCOc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)n1 CHEMBL223748 EC50 1.2 nM
Cc1cc(SC(Cc2c(F)cccc2Cl)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2037587 EC50 1.2 nM
Cc1cc(SC(Cc2c(F)cccc2C(F)(F)F)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035058 EC50 1.2 nM
C/C(=C\COc1ccccc1Cc1c(C)n[nH]c1-c1ccc(-c2ccco2)cc1)CCC(=O)O CHEMBL4740848 EC50 1.2 nM
O=C(NCCS(=O)(=O)c1ccc(C(F)(F)F)cn1)c1ccc(Cl)cc1 CHEMBL598608 IC50 1.21 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4nc5c(s4)CCC5)cc3)ccc21 CHEMBL221101 EC50 1.3 nM
COc1cc(-c2nc3c(s2)CCCO3)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL375427 EC50 1.3 nM
COc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)n1 CHEMBL220224 EC50 1.3 nM
C/C(=C\COc1ccccc1Cc1c(-c2ccc(-c3ccco3)cc2)ncn1C)CCC(=O)O CHEMBL4741090 EC50 1.3 nM
Cc1cc(Cn2ncn(-c3ccc(C(F)(F)F)cc3)c2=O)cc(C(F)(F)F)c1OC(C)(C)C(=O)O CHEMBL5081996 EC50 1.4 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4ccc5cc[nH]c5c4)cc3)ccc21 CHEMBL220893 EC50 1.5 nM
C[C@@H]1CN(c2ccc(OC(F)(F)F)cc2)C[C@H](C)N1S(=O)(=O)c1cccc2c1C[C@@H](C(=O)O)C2 CHEMBL3787155 EC50 1.5 nM
C[C@H](CCCOc1ccccc1Cn1c(Cl)cnc1-c1ccc(C(F)(F)F)cc1)CC(=O)O CHEMBL4639259 EC50 1.5 nM
C/C(=C\COc1ccccc1Cc1c(-c2ccc(-c3ccco3)cc2)noc1C)CCC(=O)O CHEMBL4744325 EC50 1.5 nM
C[C@H]1CN(c2nc3ccc(C(F)(F)F)cc3s2)CCN1CCOc1cc(CC(=O)O)ccc1Cl CHEMBL5290870 EC50 1.5 nM
C/C(=C\COc1ccccc1CN(C)C(=O)c1ccc(-c2ccco2)c(Cl)c1)CCC(=O)O CHEMBL3964816 EC50 1.59 nM
CCCc1cc(C(F)(F)F)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL219686 EC50 1.6 nM
CCCc1cc(-c2nccs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL374901 EC50 1.6 nM
CCCCOc1ccc(-c2cccc(C(=O)O)c2C)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL1081354 EC50 1.6 nM
Cc1cc(SC(Cc2ccccc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2037577 EC50 1.6 nM
COc1cc(OCC(=O)O)c(C)cc1SCc1ccc(OCc2ccc(C(F)(F)F)cc2)cc1 CHEMBL234659 pIC50 1.698 nM
CCCOc1ccc(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL376165 EC50 1.7 nM
O=C(O)COc1ccc(SCc2cc(F)ccc2OCc2ccc(C(F)(F)F)cc2)c2c1CCC2 CHEMBL232400 IC50 1.7 nM
Cc1cc(Cn2ncn(-c3ccc(C(F)(F)F)cc3)c2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5078556 EC50 1.7 nM
Cc1cc(CN2C(=O)CN(c3ccc(C(F)(F)F)c(Cl)c3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5402111 EC50 1.7 nM
Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OC(C)(C)C(=O)O CHEMBL1630384 EC50 1.8 nM
CCC(Sc1ccc(OCC(=O)O)c(C)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C CHEMBL2035068 EC50 1.8 nM
CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220836 EC50 1.9 nM
CCCc1cc(-c2nc3c(s2)CCCC3)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL2113263 EC50 1.9 nM
CCCCOc1ccc(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL229836 EC50 1.9 nM
CCO[C@H](COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL230158 EC50 1.9 nM
Cc1cc(CN2C(=O)CN(c3ccc(Br)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5440979 EC50 1.9 nM
C/C(=C\COc1ccccc1CN(C)C(=O)c1ccc(-c2ccco2)c(F)c1)CCC(=O)O CHEMBL3975891 EC50 1.93 nM
CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OCC(=O)O)c(C)c1C CHEMBL1760268 pEC50 1.995 nM
CCCc1c(OCCCOc2ccc(CCC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 CHEMBL435704 Ki 2.0 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(OC(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O CHEMBL214921 EC50 2.0 nM
CCCc1cc(-c2nc(OCC)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL387350 EC50 2.0 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(Cl)cc2-c2ccccn2)ccc1CCC(=O)O CHEMBL241299 IC50 2.0 nM
CCc1ccc(-c2ncc(CC)c(N(C)CCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)n2)cc1 CHEMBL240437 EC50 2.0 nM
Cc1cc(SCc2cc(-c3ccc(C(F)(F)F)cc3)sn2)ccc1OCC(=O)O CHEMBL258732 EC50 2.0 nM
Cc1cc(SCCc2nc(-c3ccc(C(F)(F)F)cc3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL411045 EC50 2.0 nM
Cc1cc(SCc2cc(-c3ccc(C(F)(F)F)cc3)on2)ccc1OCC(=O)O CHEMBL259873 EC50 2.0 nM
O=C(O)COc1ccc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2OCC#CCO)c2c1CCCC2 CHEMBL525989 Ki 2.0 nM
Cc1cc(OCc2nc(-c3ccc(C(=O)N(C)C(C)C)cc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL1075723 EC50 2.0 nM
Cc1cc(OCc2nc(-c3ccc(N4CCOCC4)nc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1075894 EC50 2.0 nM
Cc1nc(-c2cc(F)c(-c3ccco3)c(F)c2)c(Cc2ccccc2OCCC[C@@H](C)CC(=O)O)s1 CHEMBL4644943 EC50 2.0 nM
COc1cc(-c2nc(C)c(C(=O)N(C)C)s2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220173 EC50 2.1 nM
CCCc1c(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)ccc2c(C)noc12 CHEMBL220204 EC50 2.1 nM
COCO[C@H](COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL231223 EC50 2.1 nM
Cc1cc(SC(Cc2c(F)cccc2F)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2037588 EC50 2.1 nM
CCOc1cc(C)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220430 EC50 2.2 nM
Cc1cccc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)n1 CHEMBL220325 EC50 2.2 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4nc5c(s4)CCCC5)cc3)ccc21 CHEMBL375812 EC50 2.2 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4cccnc4)cc3)ccc21 CHEMBL219944 EC50 2.3 nM
CCCc1cc(-c2nc(OC(C)C)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL436514 EC50 2.3 nM
CCCCC(Sc1ccc(OCC(=O)O)c(C)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C CHEMBL2035070 EC50 2.3 nM
O=C(NCC1CC1)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL603424 Ki 2.37 nM
CCCc1ccccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL375098 EC50 2.4 nM
CCc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(OC)c2)n1 CHEMBL220557 EC50 2.5 nM
CCCCN(c1cccc(-c2ccc(OC(F)(F)F)cc2)c1Cl)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(C)c1C CHEMBL1760005 pEC50 2.512 nM
CCCCN(c1cccc(-c2ccc(C(F)(F)F)cc2)c1Cl)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(C)c1C CHEMBL1760428 pEC50 2.512 nM
CNC(=O)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL522152 Ki 2.54 nM
Cc1cc(SC(CCc2ccccc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2037578 EC50 2.6 nM
Cc1cc(SC(Cc2ccccc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)ccc1OCC(=O)O CHEMBL4243419 EC50 2.6 nM
C[C@H](CCCOc1ccccc1Cn1c(C(F)(F)F)cnc1-c1ccc(OC(F)(F)F)cc1)CC(=O)O CHEMBL4649443 EC50 2.6 nM
O=C(NC1CCC1)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL594625 Ki 2.61 nM
CCc1ccc(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)c(OC)c1 CHEMBL220681 EC50 2.7 nM
COc1cc(-c2nc(C)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220059 EC50 2.7 nM
CCCc1cc(C2=NC3OCCCC3S2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL221044 EC50 2.7 nM
C[C@H](CCCOc1ccccc1Cn1c(C#N)cnc1-c1ccc(C(F)(F)F)cc1)CC(=O)O CHEMBL4647214 EC50 2.7 nM
CC[C@H]1CN(c2nc3ccc(Cl)cc3s2)CCC1CCOc1cc(CC(=O)O)ccc1Cl CHEMBL5267473 EC50 2.7 nM
Cc1nc(C(F)(F)F)sc1CSc1ccc2c(ccn2CC(=O)O)c1 CHEMBL231690 IC50 2.8 nM
Cc1cc(SC(Cc2c(Cl)cccc2Cl)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035059 EC50 2.8 nM
Cc1nc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)sc1C CHEMBL220837 EC50 2.9 nM
COc1cc(-c2nc(C(F)(F)F)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL219687 EC50 2.9 nM
C[C@H](CCCOc1ccccc1Cn1c(C(F)(F)F)cnc1-c1ccc(C(F)(F)F)cc1)CC(=O)O CHEMBL4648903 EC50 2.9 nM
O=C(NC1CC1)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL596014 Ki 2.98 nM
Cc1ccc(CNC(=O)c2ccc(C(F)(F)F)cc2F)cc1Oc1ccc(OC(C)(C)C(=O)O)c(C)c1 CHEMBL237307 pIC50 2.999 nM
Cc1cc(Oc2ccc(F)c(CNC(=O)c3ccc(C(F)(F)F)cc3F)c2)ccc1OC(C)(C)C(=O)O CHEMBL237520 pIC50 2.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4cc(Cl)ccc4[nH]3)c2)ccc1CCC(=O)O CHEMBL237277 pIC50 2.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3Br)c2)ccc1OC(C)(C)C(=O)O CHEMBL236877 pIC50 2.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3C)c2)ccc1OC(C)(C)C(=O)O CHEMBL236664 pIC50 2.999 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2cscn2)c1 CHEMBL241286 pIC50 2.999 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2ccccn2)c1 CHEMBL241471 pIC50 2.999 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(CC)c2)c(-c2ccccn2)c1 CHEMBL241479 pIC50 2.999 nM
CCc1cc(OCC[C@@H](C)Oc2ccc(C(F)(F)F)cc2-c2ccccn2)ccc1CCC(=O)O CHEMBL238970 pIC50 2.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3[nH]c4ccc(Cl)cc4c3C)c2)ccc1CCC(=O)O CHEMBL235143 pIC50 2.999 nM
Cc1cc(Oc2cc(F)cc(CNC(=O)c3ccc(C(F)(F)F)cc3F)c2)ccc1OC(C)(C)C(=O)O CHEMBL392717 pIC50 2.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4ccc(Cl)cc4[nH]3)c2)ccc1CCC(=O)O CHEMBL237484 pIC50 2.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3Cl)c2)ccc1OC(C)(C)C(=O)O CHEMBL393938 pIC50 2.999 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(-c3ccccc3)noc12 CHEMBL367019 EC50 3.0 nM
Cc1cc(SCc2oc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL289887 IC50 3.0 nM
COc1cc(-c2nc(OC(C)C)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL219669 EC50 3.0 nM
COc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(OC)c2)n1 CHEMBL222508 EC50 3.0 nM
Cc1cc(OCc2nc(-c3ccc(C(F)(F)F)cc3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL428037 EC50 3.0 nM
Cc1cc(SCc2nc(-c3ccc(OC(F)(F)F)cc3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL396496 EC50 3.0 nM
Cc1cc(Oc2cccc(CNC(=O)c3c(C)c4cc(Cl)ccc4n3C)c2)ccc1CCC(=O)O CHEMBL238152 IC50 3.0 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4cc(Cl)ccc4n3C)c2)ccc1CCC(=O)O CHEMBL399417 IC50 3.0 nM
CCOc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)nc2)n1 CHEMBL241269 EC50 3.0 nM
CCc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)nc2)n1 CHEMBL240868 EC50 3.0 nM
CCC(Oc1cccc(CN(CCCOc2ccc(O)cc2)c2nc3ccccc3o2)c1)C(=O)O CHEMBL246510 EC50 3.0 nM
Cc1cc(OCc2nc(-c3ccc(C(F)(F)F)c(F)c3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL258766 EC50 3.0 nM
Cc1cc(SCc2nc(-c3ccc(OC(F)(F)F)c(Cl)c3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL259055 EC50 3.0 nM
Cc1cc(OCc2nc(-c3ccc(OC(C)C)cc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1080368 EC50 3.0 nM
Cc1cc(OCc2nc(-c3cnc(N4CCOCC4)nc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL1075836 EC50 3.0 nM
Cc1cc(CN(CC(=O)Nc2ccc(Cl)cc2Cl)C2CCCCC2)ccc1OCC(=O)O CHEMBL1081917 EC50 3.0 nM
CCc1cc(OCCc2nc(-c3ccc([N+](=O)[O-])cc3)oc2C)ncc1CCC(=O)O CHEMBL3905699 EC50 3.0 nM
Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc2c(CC(=O)O)csc2c1 CHEMBL233976 IC50 3.1 nM
CC[C@@H]1CN(Cc2cc(C)cc(CC(=O)O)c2)CCN1c1nc2ccc(C(F)(F)F)cc2s1 CHEMBL5272996 EC50 3.1 nM
CCNC(=O)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL596042 Ki 3.15 nM
CCCc1cc(-c2nc(OCC)c(C)s2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL373791 EC50 3.2 nM
Cc1cc(SC(Cc2ccccc2)c2ccc(-c3ccc(C(F)(F)F)cc3)nc2)ccc1OCC(=O)O CHEMBL4242129 EC50 3.2 nM
CCCc1cc(-c2nc(C(F)(F)F)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL374090 EC50 3.3 nM
COc1cc(-c2nc3c(s2)CCCC3)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL219617 EC50 3.3 nM
Cc1cc(-c2nc(C(F)(F)F)ns2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL219688 EC50 3.4 nM
COc1cc(-c2nc(C)c(C(C)=O)s2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220151 EC50 3.4 nM
CCOc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(OC)c2)n1 CHEMBL220894 EC50 3.4 nM
CCOC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL230050 EC50 3.4 nM
CCCc1cc(-c2nc3c(s2)CCC3)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220223 EC50 3.5 nM
O=C(O)Cc1csc2cc(OCc3ccc(COc4ccc(C(F)(F)F)cc4)cc3)ccc12 CHEMBL234589 pIC50 3.597 nM
CC[C@H]1CN(c2nc3ccc(C(F)(F)F)cc3s2)CCN1CCOc1cc(CC(=O)O)ccc1Cl CHEMBL5283926 EC50 3.6 nM
O=C(O)Cc1cc(Cl)cc(OCCC2(N3CCCC3)CCN(c3nc4ccc(C(F)(F)F)nc4s3)CC2)c1 CHEMBL5432412 EC50 3.6 nM
CCCc1c(OCCCOc2ccc(OCC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 CHEMBL173494 Ki 3.7 nM
Cc1cnc(-c2ccc(-c3ccco3)cc2)n1Cc1ccccc1OCCC[C@@H](C)CC(=O)O CHEMBL4757948 EC50 3.7 nM
Cc1cc(CC(=O)O)cc(CN2CCN(c3nc4ccc(C(F)(F)F)cc4s3)[C@H](C(C)C)C2)c1 CHEMBL5277165 EC50 3.7 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4ccoc4)cc3)ccc21 CHEMBL376418 EC50 3.8 nM
C=CCOC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL230269 EC50 3.9 nM
Cc1cc2cc(-c3ncc(C)n3Cc3ccccc3OCCCCCC(=O)O)ccc2o1 CHEMBL4635759 EC50 3.9 nM
O=C(Nc1ccc(Cl)cc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3c(cccc3C(=O)O)C2)c1 CHEMBL496136 pIC50 3.981 nM
Cc1ccc(NC(=O)c2cccc(S(=O)(=O)n3ccc4cccc(C)c43)c2)c(C(=O)O)c1 CHEMBL522224 pIC50 3.981 nM
C[C@H](CCOc1ccc(CCC(=O)O)c(F)c1)Oc1ccc(Cl)cc1Oc1ccccc1 CHEMBL215245 pIC50 3.999 nM
CCc1cc(OCC[C@@H](C)Oc2ccc(Cl)cc2Oc2ccccc2)ccc1CCC(=O)O CHEMBL215701 pIC50 3.999 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(Oc2ccccc2)c1 CHEMBL377660 pIC50 3.999 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(Cl)cc2Oc2ccccc2)ccc1CCC(=O)O CHEMBL214026 pIC50 3.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4cc(Br)ccc4[nH]3)c2)ccc1CCC(=O)O CHEMBL237485 pIC50 3.999 nM
CCc1cc(C(F)(F)F)ccc1C(=O)NCc1cccc(Oc2ccc(OC(C)(C)C(=O)O)c(C)c2)c1 CHEMBL236875 pIC50 3.999 nM
CCCc1c(OCCCOc2ccc(CC(=O)O)cc2Cl)ccc2c(C(F)(F)F)noc12 CHEMBL210768 pIC50 3.999 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(C(F)(F)F)cc2-c2ccccn2)ccc1CCC(=O)O CHEMBL241478 pIC50 3.999 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(C(F)(F)F)noc12 CHEMBL23296 pIC50 3.999 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(CC)noc12 CHEMBL279053 pIC50 3.999 nM
Cc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(C)(C)C(=O)O)c(C)c3)c2)c(C)c1 CHEMBL393939 pIC50 3.999 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3F)c2)ccc1OC(C)(C)C(=O)O CHEMBL236876 pIC50 3.999 nM
COc1cc(C(F)(F)F)ccc1C(=O)NCc1cccc(Oc2ccc(OC(C)(C)C(=O)O)c(C)c2)c1 CHEMBL237085 pIC50 3.999 nM
Cc1onc(-c2ccc(CC(=O)O)cc2Cl)c1C(=O)NCCOc1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL214295 EC50 4.0 nM
Cc1cc(CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL221755 EC50 4.0 nM
COc1cc(-c2nc(C)c(C)s2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL374925 EC50 4.0 nM
Cc1cc(CNC(=O)c2ccc(C(F)(F)F)cc2F)cc(Oc2ccc(OC(C)(C)C(=O)O)c(C)c2)c1 CHEMBL237518 EC50 4.0 nM
C#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c(C)c1C CHEMBL524063 Ki 4.0 nM
COCCC#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 CHEMBL511100 Ki 4.0 nM
Cc1cc(OCc2nc(-c3ccc(OC4CCCC4)cc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1075683 EC50 4.0 nM
Cc1cc(SC(Cc2c(F)cccc2F)c2ccc(-c3ccc(F)cc3)cc2)ccc1OCC(=O)O CHEMBL4237295 EC50 4.0 nM
Cc1cccc(OCCNC(=O)COc2ccc(CC(=O)O)cc2)c1 CHEMBL4637063 EC50 4.0 nM
COc1cc(-c2nc3c(s2)CCC3)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL222248 EC50 4.1 nM
Cc1cc(CC(=O)O)cc(CN2CCN(c3nc4ccc(C(F)(F)F)cc4s3)[C@@H](C(C)C)C2)c1 CHEMBL5290260 EC50 4.1 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(C(F)(F)F)cc3)ccc21 CHEMBL220422 EC50 4.2 nM
CCCOC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL389769 EC50 4.3 nM
Cc1cc(CC(=O)O)cc(CN2CCN(c3nc4ccc(C(F)(F)F)cc4s3)[C@H](CC(C)C)C2)c1 CHEMBL5289740 EC50 4.3 nM
CCc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)n1 CHEMBL220635 EC50 4.4 nM
CCCc1cc(-c2nc(C)c(C(=O)N(C)C)s2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220662 EC50 4.4 nM
Cc1cc(SC(Cc2ccc(-c3ccccc3)cc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035064 EC50 4.4 nM
Cc1cc(CCN2C(=O)CN(c3ccc(C(F)(F)F)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5433003 EC50 4.4 nM
Cc1cc(CN2C(=O)CN(c3ccc(OC(F)(F)F)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5409347 EC50 4.4 nM
Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(C)(C)C(=O)O CHEMBL1630380 EC50 4.5 nM
Cc1cc2c(CCc3nc(-c4ccc(Cl)cc4Cl)oc3C(C)C)noc2cc1OCC(=O)O CHEMBL1644614 EC50 4.5 nM
Cc1cc(SC(Cc2ccccc2)c2ccc(-c3cc(F)c(F)c(F)c3)cc2)ccc1OCC(=O)O CHEMBL4249120 EC50 4.5 nM
Cc1cnc(-c2ccc(-c3ccco3)cc2)n1Cc1ccccc1OCCCCC(C)(C)C(=O)O CHEMBL4764454 EC50 4.5 nM
CCC(C)C1(CCOc2cc(Cl)cc(CC(=O)O)c2)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5422049 EC50 4.5 nM
CCCc1c(OCCCOc2ccc(OC(C)C(=O)O)cc2)ccc2c(-c3ccccc3)noc12 CHEMBL172490 Ki 4.6 nM
Cc1ccc(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)c(C)c1 CHEMBL220785 EC50 4.6 nM
CCCc1cc(-c2nc(CC(=O)O)cs2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL375072 EC50 4.6 nM
CCOCC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL231528 EC50 4.6 nM
Cc1cc(SC(Cc2ccc(F)cc2F)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035060 EC50 4.6 nM
Cc1cnc(-c2ccc(C#N)cc2)n1Cc1ccccc1OCCC[C@@H](C)CC(=O)O CHEMBL4638287 EC50 4.6 nM
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1OC CHEMBL592652 Ki 4.65 nM
CCCCOc1ccc(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1 CHEMBL389903 EC50 4.8 nM
COc1ccc(CC(Sc2ccc(OCC(=O)O)c(C)c2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1 CHEMBL2037586 EC50 4.8 nM
CCCCOc1ccc(-c2cc(C(=O)O)ccc2C)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL1086861 EC50 4.9 nM
CCCc1c(OCCCOc2ccc(CC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 CHEMBL173285 Ki 5.0 nM
C[C@H](CCOc1ccc(CCC(=O)O)c(C(F)(F)F)c1)Oc1ccc(Cl)cc1Oc1ccccc1 CHEMBL213361 IC50 5.0 nM
CCc1ccc(OC(C)CCOc2ccc(OC(C)(C)C(=O)O)cc2)c(C(=O)c2ccccc2)c1 CHEMBL215582 IC50 5.0 nM
CCc1cc(Oc2cc(F)cc([C@@H](C)NC(=O)c3sc4ccc(Cl)cc4c3C)c2)ccc1CCC(=O)O CHEMBL401236 IC50 5.0 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4cc(Cl)c(Cl)cc4[nH]3)c2)ccc1CCC(=O)O CHEMBL399217 IC50 5.0 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3C)c2)ccc1CCC(=O)O CHEMBL237730 IC50 5.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2ncco2)c1 CHEMBL391470 IC50 5.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2ccncc2)c1 CHEMBL391283 IC50 5.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2cccnc2)c1 CHEMBL241472 IC50 5.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2ccccc2)c1 CHEMBL393926 IC50 5.0 nM
Cc1nc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)nc2)sc1C CHEMBL393805 EC50 5.0 nM
Cc1cc(SCc2nc(-c3ccc(C(F)(F)F)c(F)c3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL258832 EC50 5.0 nM
Cc1cc(SCc2cc(-c3ccc(C(F)(F)F)cc3)ns2)ccc1OCC(=O)O CHEMBL265421 EC50 5.0 nM
CCC#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 CHEMBL501440 Ki 5.0 nM
Cc1cc(CN2Cc3ccccc3C[C@H]2C(=O)Nc2ccc(Cl)cc2Cl)ccc1OCC(=O)O CHEMBL1643200 EC50 5.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(OC(C)(C)C(=O)O)cc2)c(C(=O)c2ccccc2)c1 CHEMBL2037003 pIC50 5.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL522619 pIC50 5.0 nM
O=C(Nc1cc(Br)ccc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL484467 pIC50 5.0 nM
C/C(=C\COc1ccccc1CN(C)C(=O)c1ccc(-c2ccco2)cc1)CCC(=O)O CHEMBL3958704 EC50 5.0 nM
Cc1cc(CCc2cc(-c3ccc(Br)cc3)on2)cc(C)c1OC(C)(C)C(=O)O CHEMBL4436335 EC50 5.0 nM
Cc1cc(Cc2cc(-c3ccc(Br)cc3)on2)cc(C)c1OC(C)(C)C(=O)O CHEMBL4470753 EC50 5.0 nM
C[C@H]1CN(c2nc3ccc(Cl)cc3s2)CCN1CCOc1cc(CC(=O)O)ccc1Cl CHEMBL5278892 EC50 5.0 nM
CCCCOc1ccc(CC(CCC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL229573 EC50 5.1 nM
COc1cc(-c2nc3ccccc3s2)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL424939 EC50 5.2 nM
Cc1cc(SC(Cc2c(F)cccc2Cl)c2ccc(-c3cccc(C(F)(F)F)c3)cc2)ccc1OCC(=O)O CHEMBL4248145 EC50 5.3 nM
Cc1cc(Cn2ncn(-c3ccc(OC(F)(F)F)cc3)c2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5084377 EC50 5.3 nM
CCOc1nc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(OC)c2)sc1CC CHEMBL219609 EC50 5.4 nM
Cc1ccc(CC(=O)O)cc1OCCN1CCN(c2nc3ccc(Cl)cc3s2)C[C@@H]1C CHEMBL5271479 EC50 5.4 nM
Cc1cnc(-c2ccc(Cl)cc2)n1Cc1ccccc1OCCC[C@@H](C)CC(=O)O CHEMBL4784739 EC50 5.5 nM
C/C(=C\COc1ccc(F)cc1CN(C)C(=O)c1ccc(-c2ccco2)cc1)CCC(=O)O CHEMBL3983906 EC50 5.51 nM
COc1ncc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)c(OC)n1 CHEMBL425116 EC50 5.6 nM
Cc1cc(Cn2ncn(-c3ccc(OC(F)(F)F)cc3)c2=O)cc(C(F)(F)F)c1OC(C)(C)C(=O)O CHEMBL5094105 EC50 5.6 nM
CCCCOc1ccc(-c2c(F)ccc(C(=O)O)c2F)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL1254672 EC50 5.7 nM
Cc1cc(SC(Cc2c(F)cccc2C(F)(F)F)c2ccc(-c3cccc(C(F)(F)F)c3)cc2)ccc1OCC(=O)O CHEMBL4240461 EC50 5.8 nM
O=C(O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4ccsc4)cc3)ccc21 CHEMBL375748 EC50 5.9 nM
CC(C)CC1(CCOc2cc(Cl)cc(CC(=O)O)c2)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5424744 EC50 5.9 nM
Cc1cc(CN2C(=O)CN(c3cccc(C(F)(F)F)c3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5432415 EC50 5.9 nM
CCc1ccc(OCCCOc2ccc(OC(C)(C)C(=O)O)cc2)c(C(=O)c2ccccc2)c1 CHEMBL213314 pIC50 5.998 nM
Cc1ccc(Oc2ccc(OC(C)(C)C(=O)O)c(C)c2)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL237519 pIC50 5.998 nM
CCc1ccc(O[C@H](CC)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1 CHEMBL2037004 pIC50 5.998 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3)c2)ccc1OC(C)(C)C(=O)O CHEMBL392058 pIC50 5.998 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(-c3ccccc3)coc12 CHEMBL278994 pIC50 5.998 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(Cl)cc3C)c2)ccc1OC(C)(C)C(=O)O CHEMBL237086 pIC50 5.998 nM
Cc1ccc(NC(=O)c2cccc(S(=O)(=O)n3ccc4c(C)cccc43)c2)c(C(=O)O)c1 CHEMBL495904 pIC50 5.998 nM
COc1cccc2c1ccn2S(=O)(=O)c1cccc(C(=O)Nc2ccc(Cl)cc2C(=O)O)c1 CHEMBL496744 pIC50 5.998 nM
CCc1ccc(OC(CC)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1 CHEMBL215127 IC50 6.0 nM
CCOc1nc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(OC)c2)sc1C CHEMBL220152 EC50 6.0 nM
CCCc1c(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)ccc2c(C(F)(F)F)noc12 CHEMBL426883 EC50 6.0 nM
Cc1cc(SCc2nc(-c3ccc(C(F)(F)F)cc3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL244574 EC50 6.0 nM
CC#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 CHEMBL501439 Ki 6.0 nM
C[C@H](O)C#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 CHEMBL502521 Ki 6.0 nM
Cc1cc(OCc2nc(-c3ccc(C(=O)N4CCCCC4)cc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL1075724 EC50 6.0 nM
Cc1cc(OCc2nc(-c3cnc(OC(C)C)nc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL1080172 EC50 6.0 nM
Cc1cc(OCc2nc(-c3cccnc3)c(-c3ccc(-c4ccccc4)cc3)o2)ccc1OCC(=O)O CHEMBL1079752 EC50 6.0 nM
CCc1cc(OCCc2nc(-c3ccc(C#N)cc3)oc2C)ncc1CCC(=O)O CHEMBL3976442 EC50 6.0 nM
CCCc1c(OCCCOc2ccc(OCC(=O)O)cc2)ccc(C(C)=O)c1O CHEMBL153057 EC50 6.0 nM
Cc1cc(SC(CCCc2ccccc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2037579 EC50 6.1 nM
Cc1cc(S[C@@H](Cc2ccccc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)ccc1OCC(=O)O CHEMBL4247027 EC50 6.1 nM
CCCc1c(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)ccc2[nH]ccc12 CHEMBL427237 EC50 6.2 nM
CCC(Oc1ccc([Se]Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C)C(=O)O CHEMBL1630381 EC50 6.2 nM
Cc1cc(SC[C@@H]2N=C(c3ccc(C(F)(F)F)cc3)S[C@@H]2C)ccc1OCC(=O)O CHEMBL4642511 EC50 6.2 nM
Cc1cc(CC(=O)O)cc(CN2CCN(c3nc4ccc(C(F)(F)F)cc4s3)[C@H](C)C2)c1 CHEMBL5289017 EC50 6.2 nM
CC[C@H]1CN(Cc2cc(C)cc(CC(=O)O)c2)CCN1c1nc2ccc(C(F)(F)F)cc2s1 CHEMBL5268424 EC50 6.2 nM
Cc1ccc(CC(=O)O)cc1OCCC1(N2CCCC2)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5406333 EC50 6.2 nM
Cc1cc(CN2C(=O)CN(c3ccc(-c4ccccc4)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5400319 EC50 6.2 nM
COCOC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL395558 EC50 6.3 nM
Cc1cc(SC(Cc2c(F)cccc2F)c2ccc(-c3cc(F)c(F)c(F)c3)cc2)ccc1OCC(=O)O CHEMBL4247929 EC50 6.3 nM
CCc1ccc(N2CC(=O)N(Cc3cc(C)c(OC(C)(C)C(=O)O)c(C)c3)C2=O)cc1 CHEMBL5406894 EC50 6.3 nM
CCCCN(c1cccc(-c2ccc(C(F)(F)F)cc2)c1C)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(C)c1C CHEMBL1760424 pEC50 6.31 nM
Cc1cc(CN2C(=O)N(c3ccc(C(F)(F)F)cc3)C(=O)C2(C)C)cc(C)c1OC(C)(C)C(=O)O CHEMBL5439116 EC50 6.5 nM
CCOc1ccc(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)cc1 CHEMBL220507 EC50 6.6 nM
COc1ccc(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)cc1 CHEMBL220627 EC50 6.7 nM
Cc1cc(SC(Cc2cc(F)c(F)c(F)c2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035062 EC50 6.7 nM
CCCOc1ccc(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1 CHEMBL229778 EC50 6.8 nM
Cc1nc(C(F)(F)F)sc1COc1ccc2c(ccn2CC(=O)O)c1 CHEMBL234801 IC50 6.8 nM
CC(=O)c1sc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)cc2)nc1C CHEMBL374545 EC50 6.9 nM
CCOC(CCc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL230177 EC50 6.9 nM
Cc1cc(SC(Cc2c(F)cccc2Cl)c2ccc(-c3cc(F)c(F)c(F)c3)cc2)ccc1OCC(=O)O CHEMBL4242161 EC50 6.9 nM
Cc1cc(CC(=O)O)cc(CN2CCN(c3nc4ccc(C(F)(F)F)cc4s3)C[C@@H]2C)c1 CHEMBL5279586 EC50 6.9 nM
CCCc1cc(C(F)(F)F)ccc1OCCCOc1ccc(OCC(=O)O)c(C)c1 CHEMBL213355 EC50 7.0 nM
CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1 CHEMBL378068 IC50 7.0 nM
CCCCOC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL230268 EC50 7.0 nM
CCOc1cccc(-c2ncc(C)c(N(C)CCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)n2)c1 CHEMBL238944 EC50 7.0 nM
Cc1cnc(-c2ccc(Cl)cc2)nc1N(C)CCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL239771 EC50 7.0 nM
Cc1cnc(-c2ccc(F)cc2)nc1N(C)CCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL393778 EC50 7.0 nM
C#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 CHEMBL495990 Ki 7.0 nM
O=C(O)COc1ccc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2Cl)c2c1CCCC2 CHEMBL496807 Ki 7.0 nM
Cc1cc(OCc2nc(-c3ccc(OC(C)C)cc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL1080349 EC50 7.0 nM
Cc1cc(OCc2nc(-c3cccnc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O CHEMBL1080173 EC50 7.0 nM
CCC(Oc1ccc([Se]Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)cc1C)C(=O)O CHEMBL1630385 EC50 7.0 nM
COC(c1ccc(OC(F)(F)F)cc1)C1CC1c1cc(C)c(OC(C)(C)C(=O)O)c(C)c1 CHEMBL3103200 EC50 7.0 nM
CCc1cc(OCCc2nc(-c3ccc(C)cc3)oc2C)ccc1CCC(=O)O CHEMBL3932461 EC50 7.0 nM
Cc1cc(SC(Cc2ccccc2)c2ccc(-c3ccc(F)cc3)cc2)ccc1OCC(=O)O CHEMBL4241411 EC50 7.0 nM
Cc1cc(CN2C(=O)CN(c3ccc(Cl)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O CHEMBL5419064 EC50 7.0 nM
O=C(O)Cc1cc(Cl)cc(OCCC2(C3CCCC3)CCN(c3nc4ccc(Cl)cc4s3)CC2)c1 CHEMBL5416699 EC50 7.1 nM
N#Cc1ccc(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)cc1 CHEMBL220508 EC50 7.3 nM
Cc1cc(SCC(C)COc2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O CHEMBL390004 EC50 7.4 nM
COc1cc(C)ccc1OCCCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL220060 EC50 7.5 nM
CC(C)C1(CCOc2cc(CC(=O)O)ccc2Cl)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5401013 EC50 7.5 nM
O=C(O)Cc1csc2cc(OCc3cc(-c4ccc(Cl)cc4)on3)ccc12 CHEMBL233978 IC50 7.7 nM
C[C@@H]1CN(CCOc2cc(CC(=O)O)ccc2Cl)CCN1c1nc2ccc(Cl)cc2s1 CHEMBL5288454 EC50 7.9 nM
O=C(Nc1ccc(Cl)cc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL485088 pIC50 7.943 nM
O=C(Nc1ccc(Br)cc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL484266 pIC50 7.943 nM
CCCCN(c1cccc(-c2ccc(Cl)cc2)c1Cl)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(C)c1C CHEMBL1760411 pIC50 7.943 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(Cc2ccccc2)c1 CHEMBL2036997 pIC50 7.998 nM
CCCc1c(OCCCOc2ccc(CC(=O)O)cc2)ccc2c(C(F)(F)F)noc12 CHEMBL210973 pIC50 7.998 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2ccsc2)c1 CHEMBL392063 pIC50 7.998 nM
CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(Cc2ccccc2)c1 CHEMBL212591 IC50 8.0 nM
Cc1coc2cc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)ccc12 CHEMBL219723 EC50 8.0 nM
Cc1cc(SCc2nc(-c3ccc(Cl)c(Cl)c3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL259856 EC50 8.0 nM
COCCCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c(C)c1C CHEMBL495817 Ki 8.0 nM
Cc1cc(OCc2nc(-c3ccc(OC(C)C)nc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O CHEMBL1079505 EC50 8.0 nM
COc1ccc(-c2nc(COc3ccc(OCC(=O)O)c(C)c3)oc2-c2ccc(OC(F)(F)F)cc2)cn1 CHEMBL1082118 EC50 8.0 nM
C[C@H](CCCOc1ccccc1Cn1c(C(F)(F)F)cnc1-c1ccc(Cl)cc1)CC(=O)O CHEMBL4643151 EC50 8.0 nM
Cc1noc2c(C)c(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)ccc12 CHEMBL220205 EC50 8.1 nM
Cc1cc(SC(Cc2c(F)c(F)c(F)c(F)c2F)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2035063 EC50 8.1 nM
C[C@H](CCCOc1ccccc1Cn1c(C(F)(F)F)cnc1-c1ccc(C#N)cc1)CC(=O)O CHEMBL4647502 EC50 8.2 nM
CSc1ccc(N2CC(=O)N(Cc3cc(C)c(OC(C)(C)C(=O)O)c(C)c3)C2=O)cc1 CHEMBL5422924 EC50 8.2 nM
CCCCOc1ccc(C[C@@H](CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F CHEMBL427071 EC50 8.3 nM
C/C(=C\COc1ccccc1Cc1c(C)nnn1-c1ccc(-c2ccco2)cc1)CCC(=O)O CHEMBL4740551 EC50 8.4 nM
CCCCC1(CCOc2cc(CC(=O)O)ccc2Cl)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5438357 EC50 8.4 nM
Cc1cc(CN2C(=O)CN(c3ccc(C(F)(F)F)cc3)C2=O)cc(C)c1OC(C)C(=O)O CHEMBL5402424 EC50 8.4 nM
Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OC(C)C(=O)O CHEMBL1630386 EC50 8.5 nM
CCCC(CCC)(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 CHEMBL461474 EC50 8.6 nM
CCc1ccc(OCCCOc2ccc3c(c2)CC[C@H]3CC(=O)O)cc1 CHEMBL220421 EC50 8.9 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2cccs2)c1 CHEMBL241078 pIC50 8.995 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4cccc(Br)c4[nH]3)c2)ccc1CCC(=O)O CHEMBL236218 pIC50 8.995 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc(/C(CC)=N/O)c1O CHEMBL23874 EC50 9.0 nM
CCCC(CCOc1ccc(CCC(=O)O)c(C)c1)Oc1ccc(CC)cc1C(=O)c1ccccc1 CHEMBL212023 IC50 9.0 nM
CC(=O)c1sc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)nc2)nc1C CHEMBL241063 EC50 9.0 nM
Cc1ccc(-c2ncc(C)c(N(C)CCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)n2)cc1 CHEMBL393593 EC50 9.0 nM
Cc1cc(SCCc2nc(-c3ccc(Cl)c(Cl)c3)ns2)ccc1OC(C)(C)C(=O)O CHEMBL259973 EC50 9.0 nM
COCC#CCOc1cc(COc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 CHEMBL503072 Ki 9.0 nM
Cc1cc(OCc2nc(-c3ccc(OC(C)C)cc3)c(-c3cccc(OC(F)(F)F)c3)s2)ccc1OCC(=O)O CHEMBL1080822 EC50 9.0 nM
Cc1cc(OCc2nc(-c3ccc(OC(C)C)cc3)c(-c3ccc(-c4ccccc4)cc3)s2)ccc1OCC(=O)O CHEMBL1076162 EC50 9.0 nM
CCCc1ccc(-c2oc(COc3ccc(OCC(=O)O)c(C)c3)nc2-c2cnc(OC)nc2)cc1 CHEMBL1080109 EC50 9.0 nM
Cc1cc(SC(Cc2c(F)cccc2F)c2ccc(-c3cccc(C(F)(F)F)c3)cc2)ccc1OCC(=O)O CHEMBL4250574 EC50 9.1 nM
Cc1cc(CC(=O)O)cc(OCCC2(N3CCCC3)CCN(c3nc4ccc(Cl)cc4s3)CC2)c1 CHEMBL5412146 EC50 9.1 nM
CCCC1(CCOc2cc(CC(=O)O)ccc2Cl)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5431819 EC50 9.2 nM
O=C(O)Cc1cc(Cl)cc(OCCC2(N3CCCC3)CCN(c3nc4ccc(C(F)(F)F)cc4s3)CC2)c1 CHEMBL5413218 EC50 9.3 nM
Cc1cc(SC(Cc2ccc(C(F)(F)F)cc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O CHEMBL2037585 EC50 9.4 nM
Cc1cc(SC(Cc2c(Cl)cccc2Cl)c2ccc(-c3cc(F)c(F)c(F)c3)cc2)ccc1OCC(=O)O CHEMBL4239431 EC50 9.5 nM
C/C(=C\COc1ccccc1Cc1sc(C)nc1-c1ccc(-c2ccco2)cc1)CCC(=O)O CHEMBL4757859 EC50 9.5 nM
CC1CCCN1C1(CCOc2cc(Cl)cc(CC(=O)O)c2)CCN(c2nc3ccc(Cl)cc3s2)CC1 CHEMBL5434437 EC50 9.7 nM
O=C(O)CCCCCOc1ccccc1CN(C(=O)c1ccc(-c2ccco2)cc1)C1CC1 CHEMBL4217067 EC50 9.8 nM
Cc1cc(CC(=O)O)cc(CN2CCN(c3nc4ccc(C(F)(F)F)cc4s3)C[C@H]2C)c1 CHEMBL5268646 EC50 9.9 nM