CCO[C@@H](Cc1ccc(OCCc2nc(-c3sccc3C)oc2C)cc1)C(=O)O CHEMBL1813010 EC50 0.0001 nM
CCO[C@@H](Cc1ccc(OCc2nc(-c3ccc(C)s3)oc2C)cc1)C(=O)O CHEMBL1813006 EC50 0.0002 nM
CCO[C@@H](Cc1ccc(OCc2nc(-c3sccc3C)oc2C)cc1)C(=O)O CHEMBL1813005 EC50 0.0003 nM
CCO[C@@H](Cc1ccc(OCc2nc(-c3cccs3)oc2C)cc1)C(=O)O CHEMBL1813003 EC50 0.0015 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3ccc(C)s3)oc2C)cc1)C(=O)O CHEMBL1813011 EC50 0.018 nM
Cc1cc(Oc2ccc3nc(COc4ccc(CC5SC(=O)NC5=O)cc4)n(C)c3c2)cc(C)c1N CHEMBL3545280 EC50 0.038 nM
CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1ccccn1 CHEMBL434063 Ki 0.0497 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3cccs3)oc2C)cc1)C(=O)O CHEMBL1813008 EC50 0.05 nM
Cc1c(C)n(Cc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12 CHEMBL3678131 IC50 0.06 nM
Cc1sc(-c2ccccc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL358379 Log EC50 0.1 nM
CCO/N=C(\CC)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL230814 EC50 0.1 nM
Cc1sc(-c2ccccc2)nc1CCOc1ccc(C[C@@](O)(C(=O)O)c2ccccc2C(=O)c2ccccc2)cc1 CHEMBL2282517 pEC50 0.1 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCCCCC2)cc1 CHEMBL3317860 Kd 0.1 nM
CC[C@@H](NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL3695832 IC50 0.1 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2C3CC4CC(C3)CC2C4)cc1 CHEMBL3317867 Kd 0.11 nM
Cc1oc(-c2ccc(F)cc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL147384 Log EC50 0.1259 nM
Cc1cncc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)c1 CHEMBL5191837 IC50 0.16 nM
O=C(NC1CCC1)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL594625 Ki 0.17 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)cc1 CHEMBL5207130 IC50 0.17 nM
CCCCO/N=C(\C)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL230705 EC50 0.19 nM
C/C(=C/C(=O)c1ccccc1)N[C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL410478 EC50 0.2 nM
Cc1c(C)n(Cc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)(C)C)cc3)cc12 CHEMBL3678128 IC50 0.2 nM
Cc1c(C)n(Cc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)(C)C)cc3)cc12 CHEMBL3678134 IC50 0.2 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Br)ccc3o2)cc1 CHEMBL5187164 IC50 0.22 nM
COc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)cc1F CHEMBL5179281 IC50 0.23 nM
Cc1ccc(-c2nc(CCOc3ccc(C[C@H](Nc4ccccc4C(=O)c4ccccc4)C(=O)O)cc3)c(C)o2)s1 CHEMBL147095 Log EC50 0.2455 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)cn1 CHEMBL5206512 IC50 0.25 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)C2CCCCC2)C(=O)O)cc1 CHEMBL2112870 Log EC50 0.2818 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4I)ccc3o2)cc1 CHEMBL5207464 IC50 0.29 nM
C/C(=N\OCC(C)C)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL388645 EC50 0.3 nM
Cc1c(C)n(Cc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2ccc(C(=O)N[C@@H](C)c3ccc(Br)cc3)cc12 CHEMBL3678133 IC50 0.3 nM
CCCOC(=O)c1ccccc1NC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL147770 Log EC50 0.302 nM
CC/C(=N\OC)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL230707 EC50 0.31 nM
Cc1ccc(-n2nc3ccc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)cc3n2)cc1 CHEMBL5204936 IC50 0.32 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL107367 Log EC50 0.3388 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@@](O)(C(=O)O)c2ccccc2C(=O)c2ccccc2)cc1 CHEMBL2282523 pEC50 0.3388 nM
C/C(=N\OCC1CC1)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL230706 EC50 0.36 nM
CCC(NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL602468 IC50 0.37 nM
CC[C@@H](OC(=O)N(Cc1ccccc1)C(=O)Nc1cc(OC)cc(OC)c1)c1cc(-c2ccc(OC(C)(C)C(=O)O)cc2)no1 CHEMBL3585575 EC50 0.38 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2ccccc2F)cc(C(C)C)c1OCC(F)F CHEMBL422088 EC50 0.4 nM
CN(CCOc1ccc(CC(Oc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL65805 Ki 0.4 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CC(C)(C)CC(C)(C)C2)cc1 CHEMBL3317863 Kd 0.4 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2C3CCCC2CCC3)cc1 CHEMBL3317865 Kd 0.41 nM
Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(O)c(C(C)(C)C)c3)cc21 CHEMBL4776913 EC50 0.41 nM
CCOC(=O)c1ccccc1NC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL148300 Log EC50 0.4266 nM
CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1ccccn1 CHEMBL4752243 Ki 0.43 nM
CC(C)(Oc1cccc(CCCN(CCOC(=O)c2ccc(N=C=O)cc2)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)c1)C(=O)O CHEMBL318696 EC50 0.5 nM
COc1ccc([C@@H](C)NC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 CHEMBL3695780 IC50 0.5 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)(C)c3ccccc3)cc12 CHEMBL3695782 IC50 0.5 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccc(Cl)cc1Cl)c1ccccc1 CHEMBL1825128 pEC50 0.5012 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ncc(Cl)cc1Cl)c1ccccc1 CHEMBL1821836 pEC50 0.5012 nM
C/C(=N\OCc1ccc(F)cc1)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL389297 EC50 0.54 nM
CCC(NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C#N)cc1)c1ccccc1 CHEMBL3695787 IC50 0.54 nM
CCCO/N=C(\C)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL231523 EC50 0.55 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)OC(C)C)C(=O)O)cc1 CHEMBL148668 Log EC50 0.5754 nM
O=C(Nc1ccc2nc(-c3ccccc3)cn2c1)c1cc([N+](=O)[O-])ccc1Cl CHEMBL5201278 IC50 0.58 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3ccsc3)oc2C)cc1)C(=O)O CHEMBL1813009 EC50 0.6 nM
Cc1c(C)n(Cc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12 CHEMBL3678125 IC50 0.6 nM
Cc1c(C)n(Cc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12 CHEMBL3678126 IC50 0.6 nM
Cc1c(C)n(Cc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12 CHEMBL3678132 IC50 0.6 nM
COc1ccc(-c2nc(CCOc3ccc(C[C@H](Nc4ccccc4C(=O)c4ccccc4)C(=O)O)cc3)c(C)o2)cc1 CHEMBL356382 Log EC50 0.6026 nM
COC(=O)c1ccccc1N[C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL106666 Log EC50 0.6166 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2C3CCCC2CC3)cc1 CHEMBL3317864 Kd 0.64 nM
Cn1cc(-c2ccccc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL446629 Log Ki 0.6918 nM
CCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(F)(F)C(F)(F)F)cc1C(C)C CHEMBL133896 EC50 0.7 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3ccc(Br)cc3)cc12 CHEMBL3695765 IC50 0.7 nM
Cc1c(C)n(Cc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3ccc(Br)cc3)cc12 CHEMBL3678127 IC50 0.7 nM
COC(=O)c1ccccc1[C@@](O)(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL2282520 pEC50 0.7079 nM
Cc1sc(N2CCOCC2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL149876 Log Ki 0.7762 nM
O=S(=O)(Nc1cc(-c2cccs2)nn1-c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL208472 EC50 0.78 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3ccc(F)cc3)cc12 CHEMBL3695846 IC50 0.79 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccc(Cl)cc1F)c1ccccc1 CHEMBL1825129 pEC50 0.7943 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2cccc(F)c2)cc(C(C)C)c1OCC(F)F CHEMBL130232 EC50 0.8 nM
Cc1ccc(-c2nc(CCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(C)s2)cc1 CHEMBL248411 EC50 0.8 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CC3CCC(C3)C2)cc1 CHEMBL3317866 Kd 0.8 nM
CCC[C@H](NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL3695847 IC50 0.8 nM
Cc1sc(-c2ccncc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL147090 Log Ki 0.871 nM
Cc1cc(-c2nc(CCOc3ccc(C[C@H](Nc4ccccc4C(=O)c4ccccc4)C(=O)O)cc3)c(C)s2)no1 CHEMBL343210 Log Ki 0.8913 nM
COc1ccc([C@H](C)NC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 CHEMBL3695776 IC50 0.9 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccncc2)C(=O)O)cc1 CHEMBL414442 Log EC50 0.912 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccnc2)C(=O)O)cc1 CHEMBL148384 Log Ki 0.9333 nM
CCc1cc(F)c2ccccc2c1CNC(=O)c1c(OC)cc(O)c2c1OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C CHEMBL2042814 EC50 0.94 nM
Cc1sc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL146301 Log Ki 0.9772 nM
Cc1oc(C2CCCCC2)nc1CCOc1ccc(C[C@](C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL264385 EC50 1.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3ccccc3OC(C)C(=O)O)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL181628 IC50 1.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3ccccc3OC(C)(C)C(=O)O)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL361395 IC50 1.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3cccc(OC(C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL435517 IC50 1.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3cccc(O[C@@H](C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL179330 IC50 1.0 nM
COc1ccc(-n2c(C)c(Cc3cccc(O[C@@H](C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL192691 IC50 1.0 nM
Cc1c(Oc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2cc(OC(F)(F)F)ccc2n1-c1noc2cc(Cl)ccc12 CHEMBL371341 IC50 1.0 nM
CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cccc(OC)c4)oc3C)ccc21 CHEMBL199794 EC50 1.0 nM
COC(=O)c1ccccc1S(=O)(=O)NC(=O)c1c(-c2ccc(OC)cc2)c2ccccc2n1Cc1cccc(C(F)(F)F)c1 CHEMBL218258 IC50 1.0 nM
Cc1oc(-c2cccc(Cl)c2)nc1CCOc1ccc(CC2(C(=O)O)CCCO2)cn1 CHEMBL425639 EC50 1.0 nM
CCO/N=C(\C)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL388422 EC50 1.0 nM
Cc1oc(-c2ccc(C(C)C)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL246205 EC50 1.0 nM
Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1cccc(O[C@@H](C)C(=O)O)c1 CHEMBL452051 IC50 1.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3ccc(F)c(O[C@@H](C)C(=O)O)c3)c3nc(OC)ccc23)cc1 CHEMBL460072 IC50 1.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3ccc(Cl)c(O[C@@H](C)C(=O)O)c3)c3nc(OC)ccc23)cc1 CHEMBL459466 EC50 1.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3cc(O[C@@H](C)C(=O)O)ccc3F)c3nc(OC)ccc23)cc1 CHEMBL462378 EC50 1.0 nM
CC(=O)c1ccccc1N[C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL474295 IC50 1.0 nM
COC(=O)c1cc2ccc(OCCc3nc(-c4ccc(OC)cc4)oc3C)cc2oc1=O CHEMBL458648 EC50 1.0 nM
COC(=O)C1Cc2ccc(OCCc3nc(-c4ccc(OC)cc4)oc3C)cc2OC1=O CHEMBL458866 EC50 1.0 nM
COC(=O)c1cc2ccc(OCCc3nc(-c4ccc(C)cc4)oc3C)cc2oc1=O CHEMBL456912 EC50 1.0 nM
COC(=O)C1Cc2ccc(OCCc3nc(-c4ccc(C)cc4)oc3C)cc2OC1=O CHEMBL515666 EC50 1.0 nM
COC(=O)c1cc2ccc(OCCc3nc(-c4cccc(C)c4)oc3C)cc2oc1=O CHEMBL515454 EC50 1.0 nM
COC(=O)C1Cc2ccc(OCCc3nc(-c4cccc(C)c4)oc3C)cc2OC1=O CHEMBL475988 EC50 1.0 nM
COC(=O)C1Cc2ccc(OCCc3nc(-c4ccc(F)cc4)oc3C)cc2OC1=O CHEMBL443910 EC50 1.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3cccc(O[C@@H](C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc23)cc1 CHEMBL489651 IC50 1.0 nM
Cc1c(Oc2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1ccc(Cl)c(O[C@@H](C)C(=O)O)c1 CHEMBL522772 IC50 1.0 nM
CCC[C@H](Oc1cccc(Cn2c(C)c(C(=O)c3ccc(Cl)cc3)c3ccc(OC(F)(F)F)cc32)c1)C(=O)O CHEMBL560160 EC50 1.0 nM
Cc1c(Cc2cccc(OCC(=O)O)c2)c2cc(OC(F)(F)F)ccc2n1C(=O)c1ccc(Cl)cc1 CHEMBL556073 IC50 1.0 nM
CCC(NC(=O)c1ccc2c(c1)c(SC)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL606422 EC50 1.0 nM
CN(CCOc1ccc(C[C@H](OCC(F)(F)F)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL1946409 EC50 1.0 nM
Cc1oc(C2CCCCC2)nc1CCOc1ccc(C[C@H](Oc2ccccc2)C(=O)O)cc1 CHEMBL2237300 pEC50 1.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccccc3)cc12 CHEMBL602469 IC50 1.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3cccs3)cc12 CHEMBL3695821 IC50 1.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccccc3Br)cc12 CHEMBL3699398 IC50 1.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(c3ccccc3)c3ccccc3)cc12 CHEMBL3695813 EC50 1.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)(C)c3ccc(Br)cc3)cc12 CHEMBL3695901 IC50 1.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3ccccc3C(F)(F)F)cc12 CHEMBL3699353 IC50 1.0 nM
CCC(NC(=O)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1)c1ccccc1 CHEMBL3678086 IC50 1.0 nM
CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 CHEMBL121 EC50 1.0 nM
CCCc1nc2ccccc2n1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4562979 EC50 1.0 nM
COCc1nc2cc(Cl)ccn2c1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4545684 EC50 1.0 nM
Cc1ccsc1-c1nc(CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)c(C)o1 CHEMBL148459 Log EC50 1.047 nM
Cc1cc(-c2ccccc2)nn1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL148797 Log EC50 1.072 nM
CCCCCNS(=O)(=O)NC(=O)CCc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2021930 EC50 1.1 nM
Cc1cc(CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)nn1-c1ccccc1 CHEMBL147935 Log Ki 1.259 nM
Cc1sc(N2CCN(C)CC2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL358325 Log EC50 1.288 nM
Cc1sc(N2CCN(C)CC2)nc1CCOc1ccc(C[C@@](O)(C(=O)O)c2ccccc2C(=O)c2ccccc2)cc1 CHEMBL2282518 pEC50 1.288 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2ccc(F)cc2)cc(C(C)C)c1OCC(F)F CHEMBL133915 EC50 1.3 nM
C/C(=C1/c2ccc(Cc3c(C4CC4)nc4cc(Cl)ccn34)cc2COc2cc(F)ccc21)c1noc(=O)[nH]1 CHEMBL4544366 EC50 1.4 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL148596 Log EC50 1.413 nM
Cc1oc(-c2ccncc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL148950 Log Ki 1.413 nM
CN(CCOc1ccc(CC(Nc2cscc2C(=O)c2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL149780 Log EC50 1.445 nM
CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL423026 Log Ki 1.479 nM
Cc1sc(-c2ccc(Cl)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL247998 EC50 1.5 nM
CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2022745 EC50 1.5 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccc(F)cc1F)c1ccccc1 CHEMBL1825127 pEC50 1.585 nM
Cc1c(C)n(Cc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)(C)C)c3)cc12 CHEMBL3678129 IC50 1.6 nM
Cc1c(C)n(Cc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)(C)C)c3)cc12 CHEMBL3678135 IC50 1.6 nM
CCCCCC[C@@H](Sc1nc2ccc(NS(=O)(=O)c3ccc(Cl)cc3Cl)cc2s1)C(=O)O CHEMBL4445084 EC50 1.6 nM
Cc1cc2nc(-c3ccc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)cc3)oc2cc1C CHEMBL5184027 IC50 1.6 nM
C/C(=C1/c2ccc(Cc3c(C4CC4)nc4cc(F)ccn34)cc2COc2cc(F)ccc21)c1noc(=O)[nH]1 CHEMBL4470932 EC50 1.7 nM
COc1ccccc1C(=O)c1ccccc1NC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O CHEMBL147021 Log Ki 1.738 nM
Cc1cccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)c1 CHEMBL5186962 EC50 1.8 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCCCCCC2)cc1 CHEMBL3317455 Kd 1.82 nM
O=C(NCC1CC1)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O CHEMBL603424 Ki 1.83 nM
COCn1c(-c2ccccc2)nc(C)c1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL149647 Log Ki 1.995 nM
CC(C)OC(Cc1ccc(OCCc2noc(-c3cccc(F)c3)n2)cc1)C(=O)O CHEMBL305723 EC50 2.0 nM
CCCc1c(OCCCCOc2ccc(OC(C)(C)C(=O)O)cc2)ccc2c(-c3ccccc3)noc12 CHEMBL263029 EC50 2.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3ccccc3O[C@@H](C)C(=O)O)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL181937 IC50 2.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3cccc(O[C@H](C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL359548 EC50 2.0 nM
CCCC(Oc1cccc(Cc2c(C)n(C(=O)c3ccc(OC)cc3)c3ccc(OC(F)(F)F)cc23)c1)C(=O)O CHEMBL445921 EC50 2.0 nM
COc1ccc2c(-n3c(C)c(Cc4cc(O[C@H](C)C(=O)O)ccc4Cl)c4cc(OC(F)(F)F)ccc43)noc2c1 CHEMBL364894 IC50 2.0 nM
CC(C)(C)c1ccc(-n2c(C(=O)O)c(Oc3cccc(C(F)(F)F)c3)c3cc(Oc4cc(Cl)c[nH]4)ccc32)cc1 CHEMBL199244 IC50 2.0 nM
COc1ccc(-c2c(C(=O)NS(C)(=O)=O)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1 CHEMBL221580 IC50 2.0 nM
COc1cccc(-c2nc(CCOc3ccc(CC4(C(=O)O)CCCO4)cn3)c(C)o2)c1 CHEMBL426550 EC50 2.0 nM
Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)Oc2cnccn2)c1 CHEMBL374344 EC50 2.0 nM
Cc1oc(-c2ccc(Oc3ccccc3)cc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)OC(C)C)c1 CHEMBL373685 EC50 2.0 nM
Cc1sc(-c2ccc(OC(F)(F)F)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL248187 EC50 2.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3cc(O[C@@H](C)C(=O)O)ccc3Cl)c3nc(OC)ccc23)cc1 CHEMBL460073 IC50 2.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3cc(O[C@@H](C)C(=O)O)ccc3F)c3nc(C)ccc23)cc1 CHEMBL509236 EC50 2.0 nM
CCCCCCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12)C(=O)O CHEMBL482740 IC50 2.0 nM
CO[C@@H](Cc1ccc(OCCc2nc(-c3ccc(C(C)C)cc3)oc2C)c2ccsc12)C(=O)O CHEMBL484409 IC50 2.0 nM
CCCO[C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12)C(=O)O CHEMBL484606 IC50 2.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@H](OCC2CC2)C(=O)O)c2sccc12 CHEMBL484001 IC50 2.0 nM
COc1ccc2c(-c3c(C)n(Cc4cc(O[C@@H](C)C(=O)O)ccc4Cl)c4cc(OC(F)(F)F)ccc34)noc2c1 CHEMBL519060 IC50 2.0 nM
CC[C@@H](Oc1cccc(-n2c(C)c(C(=O)c3ccc(OC)cc3)c3ccc(OC(F)(F)F)cc32)c1)C(=O)O CHEMBL490029 EC50 2.0 nM
CC[C@@](C)(Oc1cccc(Cn2c(C)c(C(=O)c3ccc(Cl)cc3)c3ccc(OC(F)(F)F)cc32)c1)C(=O)O CHEMBL558083 EC50 2.0 nM
Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1cccc(O[C@@H](C(=O)O)C(C)C)c1 CHEMBL562864 EC50 2.0 nM
CC[C@@H](Oc1cccc(Cn2c(C)c(C(=O)c3ccc(Cl)cc3)c3ccc(OC(F)(F)F)cc32)c1)C(=O)O CHEMBL552240 EC50 2.0 nM
Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1cccc(OCC(=O)O)c1 CHEMBL559567 EC50 2.0 nM
CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL601222 EC50 2.0 nM
COc1ccc2c(-n3c(=O)n(Cc4ccc(Cl)c(O[C@H](C)C(=O)O)c4)c4ccccc43)noc2c1 CHEMBL1947143 EC50 2.0 nM
COc1ccc2c(-n3c(=O)n(Cc4cc([C@@]5(C)OC(=O)NC5=O)ccc4Cl)c4ccccc43)noc2c1 CHEMBL1947147 EC50 2.0 nM
CCCc1c(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(CC)c3ccccc3)cc2n1C CHEMBL3115237 EC50 2.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3ccccc3O[C@H](C)C(=O)O)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL182100 EC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3ccc([N+](=O)[O-])cc3)cc12 CHEMBL3695811 IC50 2.0 nM
COC(=O)c1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 CHEMBL3695774 IC50 2.0 nM
CCC(NC(=O)c1ccc2c(ccn2Cc2cccc(-c3ccc(C(=O)O)cc3)c2)c1)c1ccccc1 CHEMBL3695807 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3cccc(Cl)c3)cc12 CHEMBL3639947 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3cccc4ccccc34)cc12 CHEMBL3695849 IC50 2.0 nM
CCC(NC(=O)c1ccc2c(c1)c(C)cn2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL3695857 IC50 2.0 nM
CCC(NC(=O)c1ccc2c(c1)cc(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL602263 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccccn3)cc12 CHEMBL3695867 IC50 2.0 nM
COc1cccc([C@@H](C)NC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3)cc2)c1 CHEMBL3695884 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NCc3ccc(Cl)cc3C(F)(F)F)cc12 CHEMBL3695888 IC50 2.0 nM
COc1cc(C(F)(F)F)ccc1[C@@H](C)NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL3699370 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@H](C)c3cccc(C(F)(F)F)c3Cl)cc12 CHEMBL3699377 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(Br)cn3)cc12 CHEMBL3699404 IC50 2.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3cccc(Br)n3)cc12 CHEMBL3699414 IC50 2.0 nM
O=S(=O)(Nc1cc(Cl)c(Oc2cnc3ccccc3c2)c(Cl)c1)c1ccc(Br)cc1F CHEMBL4094497 EC50 2.0 nM
C/C(=C1/c2ccc(Cc3c(C4CC4)nc4ccc(Cl)cn34)cc2COc2cc(F)ccc21)c1noc(=O)[nH]1 CHEMBL4532662 EC50 2.0 nM
O=C(Nc1ccccc1)c1cc([N+](=O)[O-])ccc1Cl CHEMBL375270 EC50 2.0 nM
O=C(NCc1ccccc1)c1cc(Cl)c(Cl)c(C(=O)Nc2ccccc2)c1 CHEMBL5289955 IC50 2.0 nM
CO/N=C(\C)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL231425 EC50 2.1 nM
CCCO/N=C(\C)C(Cc1ccc(OCCc2nc(-c3ccc(F)cc3)oc2C)cc1)C(=O)O CHEMBL230517 EC50 2.1 nM
CNC(=O)[C@H]1O[C@@H](n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL431733 Ki 2.18 nM
CCCCCCC(Sc1nc2ccc(NS(=O)(=O)c3ccc(Cl)cc3Cl)cc2s1)C(=O)O CHEMBL4466709 EC50 2.2 nM
Cc1ccccc1C(=O)c1ccccc1NC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O CHEMBL146355 Log Ki 2.239 nM
COc1cccc(C(=O)c2ccccc2NC(Cc2ccc(OCCN(C)c3nc4ccccc4o3)cc2)C(=O)O)c1 CHEMBL145886 Log Ki 2.291 nM
COc1cccc(CC(=O)O)c1OCCCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl CHEMBL1933819 EC50 2.3 nM
COc1ccc2c(-n3c(=O)n(Cc4ccc(Cl)c(O[C@H](C)C(=O)O)c4)c4ccc(C(F)(F)F)cc43)noc2c1 CHEMBL1946757 IC50 2.3 nM
CCCCCS(=O)(=O)NC(=O)C(C)Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2024607 EC50 2.3 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccsc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146562 Log Ki 2.344 nM
CCCc1nc2c(C)cccc2n1Cc1ccc2c(c1)COc1ccccc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4278109 EC50 2.4 nM
CCOC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O CHEMBL306229 Ki 2.5 nM
C/C(=C1/c2ccc(Cc3c(C4CC4)nc4c(Cl)cccn34)cc2COc2cc(F)ccc21)c1noc(=O)[nH]1 CHEMBL4570541 EC50 2.5 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccc(Cl)c(Cl)c1)c1ccccc1 CHEMBL1825110 pEC50 2.512 nM
Cc1[nH]c(-c2ccccc2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL149835 Log Ki 2.57 nM
COCCNc1nc(CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)c(C)s1 CHEMBL359285 Log Ki 2.57 nM
CCCCCS(=O)(=O)NC(=O)CCc1ccc(OC(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2022744 EC50 2.6 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc(C(F)(F)F)c2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146637 Log Ki 2.63 nM
Cc1sc(N2CCN(S(C)(=O)=O)CC2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL146650 Log Ki 2.63 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2C(F)(F)F)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146579 Log Ki 2.692 nM
Cc1cccc(C(=O)c2ccccc2NC(Cc2ccc(OCCN(C)c3nc4ccccc4o3)cc2)C(=O)O)c1 CHEMBL150215 Log Ki 2.692 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc3ccccc23)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL145958 Log EC50 2.692 nM
CCC(C)(C)c1cc(/C(C)=C(F)\C=C\C(C)=C\C(=O)O)c(OCC(F)F)c(C(C)(C)CC)c1 CHEMBL130231 EC50 2.7 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2cc(F)cc(F)c2)cc(C(C)C)c1OCC(F)F CHEMBL337393 EC50 2.7 nM
CCCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(F)(F)C(F)(F)F)cc1C(C)C CHEMBL132568 EC50 2.7 nM
CCO[C@@H](Cc1ccc(OCc2nc(-c3ccsc3)oc2C)cc1)C(=O)O CHEMBL1813004 EC50 2.7 nM
CCCc1nc2ccccc2n1Cc1ccc2c(c1)COc1ccccc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4286027 EC50 2.7 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccs2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146584 Log Ki 2.754 nM
Cc1ccc(C(=O)c2ccccc2NC(Cc2ccc(OCCN(C)c3nc4ccccc4o3)cc2)C(=O)O)cc1 CHEMBL150232 Log Ki 2.818 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCCC2)cc1 CHEMBL3317858 Kd 2.85 nM
CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)C2CCCCC2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL2112871 Log EC50 2.884 nM
C/C(=N\OCCF)C(Cc1ccc(OCCc2nc(-c3ccc(F)cc3)oc2C)cc1)C(=O)O CHEMBL230518 EC50 2.9 nM
CC(C)OC(Cc1ccc(OCc2noc(-c3ccc(C(C)(C)C)cc3)n2)cc1)C(=O)O CHEMBL76676 EC50 3.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@](C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL81248 EC50 3.0 nM
CCC(Oc1ccccc1Cc1c(C)n(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(=O)O CHEMBL179542 IC50 3.0 nM
CCC(Oc1cccc(Cc2c(C)n(C(=O)c3ccc(OC)cc3)c3ccc(OC(F)(F)F)cc23)c1)C(=O)O CHEMBL178236 IC50 3.0 nM
COc1ccc(C(=O)n2c(C)c(Cc3cccc(OC(C)(C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 CHEMBL181554 IC50 3.0 nM
Cc1oc(-c2cccs2)nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL82602 Ki 3.0 nM
Cc1c(Oc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2cc(OC(F)(F)F)ccc2n1-c1noc2cc(Cl)ccc12 CHEMBL363805 EC50 3.0 nM
COc1ccc(-c2c(C(=O)NS(=O)(=O)c3ccccc3)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1 CHEMBL376627 IC50 3.0 nM
CCCOC(=O)N1CCc2c(OCCc3nc(-c4ccc(-c5ccccc5)cc4)oc3C)ccc(CCC(=O)O)c2C1 CHEMBL219836 EC50 3.0 nM
CCO/N=C(\C)C(Cc1ccc(OCCc2nc(-c3ccc(F)cc3)oc2C)cc1)C(=O)O CHEMBL230411 EC50 3.0 nM
Cc1oc(-c2ccc(Cl)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL247399 EC50 3.0 nM
CCc1ccc(-c2nc(CCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(C)o2)cc1 CHEMBL246203 EC50 3.0 nM
COc1ccc(-c2nc(CCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(C)o2)cc1 CHEMBL248261 EC50 3.0 nM
Cc1c(Oc2ccc(Cl)cc2)c2ccc(Cl)nc2n1Cc1ccc(Cl)c(O[C@@H](C)C(=O)O)c1 CHEMBL461944 IC50 3.0 nM
Cc1c(Oc2ccc(Cl)cc2)c2ccc(F)nc2n1Cc1ccc(Cl)c(O[C@@H](C)C(=O)O)c1 CHEMBL518499 IC50 3.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3ccc(F)c(O[C@@H](C)C(=O)O)c3)c3ncccc23)cc1 CHEMBL507477 EC50 3.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3cc(O[C@@H](C)C(=O)O)ccc3F)c3ncccc23)cc1 CHEMBL455127 EC50 3.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(OCC(C)C)C(=O)O)c2sccc12 CHEMBL483341 IC50 3.0 nM
COc1cc(OC)cc(-c2nc(CCOc3ccc(C[C@H](OC)C(=O)O)c4sccc34)c(C)o2)c1 CHEMBL521007 IC50 3.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@H](OCC(F)(F)F)C(=O)O)c2sccc12 CHEMBL484607 IC50 3.0 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)c2ccsc12)C(=O)O CHEMBL485187 IC50 3.0 nM
Cc1oc(-c2ccccc2)nc1CCCc1ccc(C[C@@H](C(=O)O)n2nccn2)cc1 CHEMBL594034 IC50 3.0 nM
CCCc1c(SC)c2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL590983 EC50 3.0 nM
CCO[C@@H](Cc1ccc(OCc2nc(-c3ccc(-c4ccccc4)s3)oc2C)cc1)C(=O)O CHEMBL1813007 EC50 3.0 nM
CC[C@H](NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 CHEMBL1230353 IC50 3.0 nM
Cc1ccccc1[C@H](C)NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL3699396 IC50 3.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(Cl)c3)cc12 CHEMBL3735987 IC50 3.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)CCc3ccccc3)cc12 CHEMBL3695850 IC50 3.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(Cl)c3)cc12 CHEMBL3695895 IC50 3.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)C3COc4ccccc4O3)cc12 CHEMBL3699359 IC50 3.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@H](C)c3c(F)ccc(F)c3F)cc12 CHEMBL3699381 IC50 3.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cc(C(F)(F)F)ccc3Cl)cc12 CHEMBL3699429 IC50 3.0 nM
CCC(NC(=O)c1ccc2c(ccn2Cc2ccc(Cl)nc2)c1)c1ccccc1 CHEMBL3678106 IC50 3.0 nM
COc1ccc(OC(=O)N(CC(=O)O)Cc2ccc(OCCc3nc(-c4ccccc4)oc3C)cc2)cc1 CHEMBL186179 EC50 3.0 nM
C/C(=C1/c2ccc(Cn3c(C4CC4)nc4cscc43)cc2COc2cc(F)ccc21)c1noc(=O)[nH]1 CHEMBL4461571 EC50 3.0 nM
COc1ccc(Oc2cc(N(C)CCOc3ccc(CC4SC(=O)NC4=O)cc3)ncn2)cc1 CHEMBL3585580 EC50 3.0 nM
CCCc1c(OCCCCOc2cccc(CC(=O)O)c2)ccc2c(-c3ccccc3)noc12 CHEMBL435523 Ki 3.1 nM
CCCCCS(=O)(=O)[N-]C(=O)C(C)(C)Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2024608 EC50 3.1 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC2SC(=O)NC2=O)cc1 CHEMBL59132 Log EC50 3.162 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccc(Cl)cc1)c1ccccc1 CHEMBL1825125 pEC50 3.162 nM
COc1ccc2c(-n3c(=O)n(Cc4ccc(Cl)c(O[C@H](C)C(=O)O)c4)c4cc(OC(F)(F)F)ccc43)noc2c1 CHEMBL1946756 IC50 3.2 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc(N)c2)C(=O)O)cc1 CHEMBL347788 Log Ki 3.236 nM
CCC(OC(=O)N(Cc1ccccc1)C(=O)Nc1cc(OC)cc(OC)c1)c1cc(-c2ccc(OC(C)(C)C(=O)O)cc2)no1 CHEMBL4448767 EC50 3.3 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4F)ccc3o2)cc1 CHEMBL5206276 EC50 3.3 nM
CCc1ccc(-c2nc3ccc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)cc3n2C)cc1 CHEMBL5199152 IC50 3.3 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)Cc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146822 Log Ki 3.311 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc(CO)c2)C(=O)O)cc1 CHEMBL146530 Log Ki 3.388 nM
CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCN2CCCC2=O)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2022747 EC50 3.4 nM
O[C@@H]1[C@H](O)CS[C@H]1n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc21 CHEMBL413686 Ki 3.42 nM
CN(CCOc1ccc(CC(Nc2ccsc2C(=O)c2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL345541 Log EC50 3.467 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 CHEMBL1651239 EC50 3.6 nM
CCCOc1ccc(C[C@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 CHEMBL1651238 EC50 3.6 nM
CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 CHEMBL5199658 EC50 3.6 nM
CCc1ccc2ccccc2c1CNC(=O)c1c(OC)cc(O)c2c1OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C CHEMBL2042803 EC50 3.7 nM
C[C@@H](Oc1ccc(Cc2ccc(OCc3coc(-c4ccccc4)n3)cc2)cc1)C(=O)O CHEMBL4073499 Kd 3.7 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3n2C)cc1 CHEMBL5183657 EC50 3.7 nM
CN(CCOc1ccc(CC(Nc2ccccc2Oc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL147826 Log Ki 3.715 nM
CCCc1nc2ccccc2n1Cc1ccc2c(c1)COc1c(F)cccc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4518548 EC50 3.8 nM
O=C(Nc1ccc2oc(-c3ccccc3Br)nc2c1)c1cc([N+](=O)[O-])ccc1Cl CHEMBL2324298 EC50 3.9 nM
Cc1oc(-c2cccc[s+]2)nc1CCOc1ccc(C[C@@](C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL2237301 pEC50 3.981 nM
Cc1oc(-c2cccs2)nc1CCOc1ccc(C[C@](C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL77502 pEC50 3.981 nM
CC(C)OC(Cc1ccc(OCCc2noc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)cc1)C(=O)O CHEMBL80979 EC50 4.0 nM
CC(C)OC(Cc1ccc(OCCc2noc(-c3cccc(Cl)c3)n2)cc1)C(=O)O CHEMBL78442 EC50 4.0 nM
CC(C)OC(Cc1ccc(OCc2noc(-c3ccc(C(C)C)cc3)n2)cc1)C(=O)O CHEMBL80364 EC50 4.0 nM
CC(C)(Oc1cccc(CCCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)C(=O)Cc2ccc(C(F)(F)F)cc2)c1)C(=O)O CHEMBL102004 EC50 4.0 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(-c3ccccc3)noc12 CHEMBL367019 EC50 4.0 nM
CC(C)O[C@@H](Cc1ccc(OCc2noc(-c3ccc(C(C)C)cc3)n2)cc1)C(=O)O CHEMBL189146 EC50 4.0 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(C(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O CHEMBL213315 EC50 4.0 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1 CHEMBL212911 EC50 4.0 nM
Cc1oc(-c2ccc(-c3ncccn3)cc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)OC(C)C)c1 CHEMBL223128 EC50 4.0 nM
CCO/N=C(\C)C(Cc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL230305 EC50 4.0 nM
COc1ccc(-c2nc(CCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(C)s2)cc1 CHEMBL248413 EC50 4.0 nM
Cc1ccc(-c2nc(CCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(C)o2)cc1 CHEMBL246208 EC50 4.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@@H]2C(=O)N(c3ccc(C(C)(C)C)cc3)[C@@H]2C(=O)O)cc1 CHEMBL256468 EC50 4.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1cccc(Cc2nn(-c3ccccc3)nc2CC(=O)O)c1 CHEMBL491751 EC50 4.0 nM
Cc1c(Oc2ccc(Cl)cc2)c2ccc(F)nc2n1Cc1cc(O[C@@H](C)C(=O)O)ccc1Cl CHEMBL461378 EC50 4.0 nM
Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CCC(=O)O)c2ccccc2)cc1 CHEMBL592054 EC50 4.0 nM
CCCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12)C(=O)O CHEMBL521462 IC50 4.0 nM
Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1cccc(O[C@H](C)C(=O)O)c1 CHEMBL461571 EC50 4.0 nM
CC[C@H](Oc1cccc(Cn2c(C)c(C(=O)c3ccc(Cl)cc3)c3ccc(OC(F)(F)F)cc32)c1)C(=O)O CHEMBL549746 IC50 4.0 nM
COc1cccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)c1 CHEMBL3695837 IC50 4.0 nM
Cc1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 CHEMBL3695840 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccc(I)cc3)cc12 CHEMBL3695766 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccc(Cl)cc3)cc12 CHEMBL3695773 IC50 4.0 nM
CCC(NC(=O)c1ccc2c(ccn2Cc2ccccc2-c2cccc(C(=O)O)c2)c1)c1ccccc1 CHEMBL3695809 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccc(N)cc3)cc12 CHEMBL3695830 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(F)c3Cl)cc12 CHEMBL3695891 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@H](C)c3cc(C(F)(F)F)ccc3C(F)(F)F)cc12 CHEMBL3695894 IC50 4.0 nM
CC[C@@H](NC(=O)c1ccc2c(ccn2Cc2ccccc2-c2cccc(C(=O)O)c2)c1)c1ccccc1 CHEMBL3695910 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)C3CCCCC3)cc12 CHEMBL3699358 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(C4CC4)cn3)cc12 CHEMBL3699405 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cc(Cl)ccn3)cc12 CHEMBL3699408 IC50 4.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(Cl)cc3Cl)cc12 CHEMBL3699430 IC50 4.0 nM
CC(C)(NC(=O)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1)c1ccccc1 CHEMBL3678089 IC50 4.0 nM
CCc1cc(OCCc2nc(-c3ccc(C)cc3)oc2C)ccc1CCC(=O)O CHEMBL3932461 EC50 4.0 nM
O=S(=O)(Nc1cc(Cl)c(Oc2cnc3ccccc3c2)c(Cl)c1)c1ccc(Br)cc1OC(F)(F)F CHEMBL4100158 EC50 4.0 nM
O=S(=O)(Nc1cc(Cl)c(Oc2cnc3ccccc3c2)c(Cl)c1)c1ccc(Cl)cc1Cl CHEMBL1236924 EC50 4.0 nM
Cc1ccc(-c2nc3ccc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)cc3o2)cc1 CHEMBL5182665 EC50 4.0 nM
CCCCOc1c(/C(C)=C(F)\C=C\C(C)=C\C(=O)O)cc(C(C)C)cc1C(C)C CHEMBL131826 EC50 4.1 nM
COc1ccc2c(-n3c(=O)n(Cc4ccc(Cl)c(O[C@H](C)C(=O)O)c4)c4cc(C(F)(F)F)ccc43)noc2c1 CHEMBL1946755 IC50 4.1 nM
COc1ccc2c(-n3c(=O)n(Cc4ccc(Cl)c(O[C@H](C)C(=O)O)c4)c4ccc(OC(F)(F)F)cc43)noc2c1 CHEMBL1946758 IC50 4.1 nM
Cc1cccc2c(-n3c(=O)n(Cc4ccc(Cl)c(O[C@H](C)C(=O)O)c4)c4cc(C(F)(F)F)ccc43)noc12 CHEMBL1946571 EC50 4.1 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccc(CO)cc2)C(=O)O)cc1 CHEMBL145824 Log Ki 4.169 nM
Cc1cc(OC(F)F)ccc1NC(=O)c1cc(C(=O)NCc2ccc(F)cc2)c(F)cc1Cl CHEMBL5267263 IC50 4.2 nM
Cc1sc(N2CCNCC2)nc1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL146231 Log Ki 4.365 nM
Cc1ccc(Oc2ccc3nc(COc4cccc(C(=O)O)c4)n(C)c3c2)cc1F CHEMBL4172322 EC50 4.4 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3ccc(-c4ccccc4)s3)oc2C)cc1)C(=O)O CHEMBL1813012 EC50 4.5 nM
CCCCCS(=O)(=O)NC(=O)OCCCc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2022134 EC50 4.5 nM
COCc1nc2c(Cl)cccn2c1Cc1ccc2c(c1)COc1cc(F)ccc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4559460 EC50 4.5 nM
CNC(=O)[C@H]1S[C@@H](n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)[C@H](O)[C@@H]1O CHEMBL200732 Ki 4.6 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@@H](C(=O)O)n2cccc2)cc1 CHEMBL104850 pEC50 4.677 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@@]2(C(=O)O)C=CC=CO2)cc1 CHEMBL2282522 pEC50 4.677 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2cccs2)cc(C(C)C)c1OCC(F)F CHEMBL130374 EC50 4.7 nM
Cc1cc(CN(Cc2ccco2)Cc2nc(-c3ccccc3)oc2C)cc(C)c1OC(C)(C)C(=O)O CHEMBL2204595 EC50 4.7 nM
O=C(Nc1ccncc1)c1cc([N+](=O)[O-])ccc1Cl CHEMBL510698 IC50 4.7 nM
Cc1nc(-c2ccccc2)nn1CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 CHEMBL342292 Log Ki 4.786 nM
COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(F)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C CHEMBL2042810 EC50 4.8 nM
Cc1cc(-c2nnco2)ccc1NC(=O)c1cc(C(=O)NCc2ccc(F)c(F)c2)c(F)cc1Cl CHEMBL5273393 IC50 4.8 nM
COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccc(Cl)cc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C CHEMBL2042809 EC50 4.9 nM
C[C@H](Oc1ccc(Cc2ccc(OCc3coc(-c4ccccc4)n3)cc2)cc1)C(=O)O CHEMBL4092600 Kd 4.9 nM
CO[C@@H](Cc1ccc(OCCCOc2ccc(C(=O)c3ccccc3)cc2)c(Cl)c1)C(=O)O CHEMBL181644 IC50 5.0 nM
CO[C@@H](Cc1ccc(OCCCOc2ccc(C(=O)c3ccccc3)cc2)cc1)C(=O)O CHEMBL363532 IC50 5.0 nM
CC(C)(C)c1ccc(-n2c(C(=O)O)c(Oc3cccc(C(F)(F)F)c3)c3cc(Oc4cc(C(F)(F)F)c[nH]4)ccc32)cc1 CHEMBL370443 IC50 5.0 nM
Cc1cc(OCC[C@@H](C)Oc2ccc(OC(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O CHEMBL214921 EC50 5.0 nM
COc1ccc(-c2nc(CCOc3ccc(CC4(C(=O)O)CCCO4)cn3)c(C)o2)cc1 CHEMBL221649 EC50 5.0 nM
Cc1cccc(-c2nc(CCOc3ccc(CC4(C(=O)O)CCCO4)cn3)c(C)o2)c1 CHEMBL374448 EC50 5.0 nM
COc1cccc(-c2nc(CCOc3ccc(CC4(C(=O)O)CCCO4)nc3)c(C)o2)c1 CHEMBL221438 EC50 5.0 nM
CCCO/N=C(\C)C(Cc1ccc(OCc2nc(C(C)C)oc2C)cc1)C(=O)O CHEMBL230519 EC50 5.0 nM
C/C(=N/OCc1ccc(F)cc1)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O CHEMBL230304 EC50 5.0 nM
Cc1ccc(CNC(=O)c2ccc(C(F)(F)F)cc2F)cc1Oc1ccc(OC(C)(C)C(=O)O)c(C)c1 CHEMBL237307 IC50 5.0 nM
CCc1oc(-c2ccc(C)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL247660 EC50 5.0 nM
Cc1sc(-c2ccc(C(C)C)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL246209 EC50 5.0 nM
Cc1sc(-c2ccc3c(c2)OCO3)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL248412 EC50 5.0 nM
Cc1oc(-c2ccc(C(C)C)cc2)nc1CCOc1ccc(C[C@H](OCC2CC2)C(=O)O)c2sccc12 CHEMBL485188 IC50 5.0 nM
Cc1oc(-c2ccccc2)nc1CCCc1ccc(CC(C(=O)O)n2nccn2)cc1 CHEMBL593796 IC50 5.0 nM
Cc1cccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)c1 CHEMBL3695839 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)(C)C)c3)cc12 CHEMBL3735906 IC50 5.0 nM
CCOc1ccc([C@H](C)NC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 CHEMBL3699397 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)(C)C)cc3)cc12 CHEMBL3735924 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3cccc(C(C)C)c3)cc12 CHEMBL3735503 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)(C)C)cc3)cc12 CHEMBL3695761 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccc(F)cc3)cc12 CHEMBL3695814 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(F)cc3F)cc12 CHEMBL3695873 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@H](C)c3cccc(Cl)c3Cl)cc12 CHEMBL3695892 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NCc3cccc(C(C)C)c3)cc12 CHEMBL3695903 IC50 5.0 nM
CC[C@@H](NC(=O)c1ccc2c(ccn2Cc2ccccc2-c2ccc(C(=O)O)cc2)c1)c1ccccc1 CHEMBL3695908 IC50 5.0 nM
COc1ccc(F)cc1[C@@H](C)NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL3699351 IC50 5.0 nM
O=C(NCc1ccccc1)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1 CHEMBL3678087 IC50 5.0 nM
Cc1c(C)n(Cc2ccc(Cl)c(O[C@@H](C)C(=O)O)c2)c2ccc(C(=O)N[C@@H](C)c3cccc(OC(C)C)c3)cc12 CHEMBL3678130 IC50 5.0 nM
Cc1c(C)n(Cc2cc(O[C@@H](C)C(=O)O)ccc2Cl)c2ccc(C(=O)N[C@@H](C)c3cccc(OC(C)C)c3)cc12 CHEMBL3678136 IC50 5.0 nM
CCc1cc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)ccc1CCC(=O)O CHEMBL3920204 EC50 5.0 nM
Cc1cc(C2COC2)cnc1NC(=O)c1cc(C(=O)NCc2ccc(F)c(F)c2)c(F)cc1Cl CHEMBL5282503 IC50 5.0 nM
CN(CCOc1ccc(CC(Nc2cccc3c2C(=O)c2ccccc2C3=O)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL358137 Log EC50 5.012 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccccc1OC)c1ccccc1 CHEMBL1825123 pEC50 5.012 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccc(C(F)(F)F)cc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146217 Log Ki 5.129 nM
CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(-c3ccccc3)coc12 CHEMBL278994 EC50 5.2 nM
CCCO/N=C(\C)C(Cc1ccc(OCCc2nc(C(C)C)oc2C)cc1)C(=O)O CHEMBL230623 EC50 5.2 nM
CCCCCS(=O)(=O)NC(=O)/C(C)=C/c1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2021928 EC50 5.2 nM
CCOC(Cc1ccc(OC(=O)Cc2ccc(NC(=O)OC(C)(C)C)cc2)c(Cc2ccccc2)c1)C(=O)O CHEMBL3893980 EC50 5.2 nM
Cc1ccccc1-c1nc2cc(NC(=O)c3cc([N+](=O)[O-])ccc3Cl)ccc2o1 CHEMBL5201306 EC50 5.2 nM
Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc1)O2 CHEMBL148301 Log Ki 5.248 nM
C/C(=C1/c2ccc(Cc3c(C4CC4)nc4ccccn34)cc2COc2cc(F)ccc21)c1noc(=O)[nH]1 CHEMBL4570877 EC50 5.3 nM
CCCCCS(=O)(=O)NC(=O)C1CC1c1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2024609 EC50 5.5 nM
COc1ccc(C(=O)c2ccccc2NC(Cc2ccc(OCCN(C)c3nc4ccccc4o3)cc2)C(=O)O)cc1 CHEMBL149381 Log Ki 5.623 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc(C(F)(F)F)ccc4Cl)ccc3o2)cc1 CHEMBL5200843 EC50 5.8 nM
CCc1ccc(O[C@H](C)CCOc2ccc(OC(C)(C)C(=O)O)cc2)c(C(=O)c2ccccc2)c1 CHEMBL2037003 pIC50 5.998 nM
CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(Oc2ccccc2)c1 CHEMBL377660 pIC50 5.998 nM
CC(C)OC(Cc1ccc(OCCc2noc(-c3cccc(C(F)(F)F)c3)n2)cc1)C(=O)O CHEMBL80791 EC50 6.0 nM
Cc1oc(-c2cccc(-c3ccccc3)c2)nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL81676 EC50 6.0 nM
CC(C)(Oc1ccc(CCN(C(=O)Nc2ccc(F)cc2F)C2CCCCCC2)cc1)C(=O)O CHEMBL124079 EC50 6.0 nM
CC[C@H](C(=O)O)[C@@H]1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)ccc21 CHEMBL200162 EC50 6.0 nM
CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccc5c(c4)OCC5)oc3C)ccc21 CHEMBL200138 EC50 6.0 nM
CCc1ccc(OC(C)CCOc2ccc(OC(C)(C)C(=O)O)cc2)c(C(=O)c2ccccc2)c1 CHEMBL215582 IC50 6.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(C[C@]2(C(=O)O)CCCO2)cn1 CHEMBL221123 Ki 6.0 nM
Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCOc1ccc(CC2(C(=O)O)CCCO2)cn1 CHEMBL221641 EC50 6.0 nM
CCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)nc1)C(=O)O CHEMBL220597 EC50 6.0 nM
Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL246207 EC50 6.0 nM
Cc1cc(CNC(=O)c2cc(-c3ccc(C(C)(C)C)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O CHEMBL518348 EC50 6.0 nM
C/C(=N\OCc1sc(-c2ccc(C(F)(F)F)cc2)nc1C)c1ccc(OCC(=O)O)c(C)c1 CHEMBL1644299 EC50 6.0 nM
O=S(=O)(Nc1cc(Cl)c(Oc2cncc(Cl)c2)c(Cl)c1)c1ccc(Cl)cc1Cl CHEMBL2331772 EC50 6.0 nM
CCCc1[nH]c2cc(C(=O)NC(CC)c3ccccc3)ccc2c1Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL3115238 EC50 6.0 nM
Cc1ccccc1CNC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL3695841 IC50 6.0 nM
CCc1ccccc1[C@H](C)NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1 CHEMBL3699399 IC50 6.0 nM
CCC(NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)c1ccccc1 CHEMBL3695789 IC50 6.0 nM
CCC(NC(=O)c1ccc2c(ccn2Cc2cccc(-c3ccccc3C(=O)O)c2)c1)c1ccccc1 CHEMBL3695806 IC50 6.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccccc3Cl)cc12 CHEMBL3695842 IC50 6.0 nM
CCC(NC(=O)c1ccc2c(ccn2Cc2ccc(-c3ccccc3C(=O)O)cc2)c1)c1ccccc1 CHEMBL3695855 IC50 6.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccnc4ccccc34)cc12 CHEMBL3695872 IC50 6.0 nM
Cc1ccc(F)c([C@H](C)NC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)c1 CHEMBL3699357 IC50 6.0 nM
CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC2CC2)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2024619 EC50 6.2 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccc(F)c(Cl)c1)c1ccccc1 CHEMBL1825126 pEC50 6.31 nM
CC(/C=C/C(F)=C(/C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1OCC(F)F)=C\C(=O)O CHEMBL111217 EC50 6.4 nM
CCc1ccc(CCOc2ccc(C[C@H](Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)nc1 CHEMBL346219 Log Ki 6.457 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)C2CCCC2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL149714 Log Ki 6.457 nM
Cc1cccc(-c2nc3cc(NC(=O)c4cc(C(=O)NCc5ccc(F)c(F)c5)c(F)cc4Cl)ccc3o2)c1 CHEMBL5281842 IC50 6.6 nM
CCCCCS(=O)(=O)NC(=O)C(Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl)OC CHEMBL2024610 EC50 6.7 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCCCC2)cc1 CHEMBL3317859 EC50 6.7 nM
CCO/N=C(\C)C(Cc1ccc(OCc2nc(-c3ccc(F)cc3)oc2C)cc1)C(=O)O CHEMBL230409 EC50 6.8 nM
CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCC(=O)N(CC)CC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2022746 EC50 6.9 nM
CO[C@@H](Cc1ccc(C#CCCCOc2ccc(Oc3ccccc3)cc2)cc1)C(=O)O CHEMBL182230 pIC50 6.998 nM
Cc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(C)(C)C(=O)O)c(C)c3)c2)c(C)c1 CHEMBL393939 pIC50 6.998 nM
COc1cc(C(F)(F)F)ccc1C(=O)NCc1cccc(Oc2ccc(OC(C)(C)C(=O)O)c(C)c2)c1 CHEMBL237085 pIC50 6.998 nM
Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL312717 EC50 7.0 nM
COc1ccc(-c2c(C(=O)NS(=O)(=O)c3ccccc3C)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1 CHEMBL217962 IC50 7.0 nM
COc1ccc(-c2c(C(=O)NS(=O)(=O)c3ccc(F)cc3)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1 CHEMBL218231 IC50 7.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)Oc2cnccn2)c1 CHEMBL223350 EC50 7.0 nM
CCc1oc(-c2ccccc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL247659 EC50 7.0 nM
Cc1sc(-c2ccc(F)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL247620 EC50 7.0 nM
Cc1oc(-c2ccc(F)cc2)nc1CCOc1ccc2c(c1)CC[C@H]2CC(=O)O CHEMBL246206 EC50 7.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(Cc2nn(-c3ccccc3)nc2CC(=O)O)cc1 CHEMBL491142 IC50 7.0 nM
CCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12)C(=O)O CHEMBL485537 IC50 7.0 nM
CCCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccccc12)C(=O)O CHEMBL519974 IC50 7.0 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2sccc12)C(=O)O CHEMBL519351 EC50 7.0 nM
CCO[C@@H](Cc1ccc(OCCN2CCC(C)(C)c3cc(/C(=N/OCc4ccccc4)c4ccccc4)ccc32)cc1)C(=O)O CHEMBL556643 EC50 7.0 nM
CCCOc1ccc(C[C@@H](Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCC(C)(C)C2)cc1 CHEMBL3317861 EC50 7.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C4CC4)c3)cc12 CHEMBL3699424 IC50 7.0 nM
COc1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 CHEMBL3695838 IC50 7.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccccc3F)cc12 CHEMBL3695883 IC50 7.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3-c3n[nH]c(=O)o3)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(C(C)C)c3)cc12 CHEMBL3699390 IC50 7.0 nM
O=C(NCc1cccs1)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1 CHEMBL3678090 IC50 7.0 nM
CCC(NC(=O)c1ccc2c(ccn2S(=O)(=O)c2cccc3ccccc23)c1)c1ccccc1 CHEMBL3678105 IC50 7.0 nM
CCCc1nc2ccccc2n1Cc1ccc2c(c1)COc1ccc(F)cc1/C2=C(\C)c1noc(=O)[nH]1 CHEMBL4515010 EC50 7.0 nM
O=C(Nc1ccc2oc(-c3cccc(Cl)c3)nc2c1)c1cc([N+](=O)[O-])ccc1Cl CHEMBL5174641 EC50 7.2 nM
COCCOCc1cc(F)ccc1CNC(=O)c1cc(C(=O)Nc2ccc(C(F)(F)F)cc2C)c(Cl)cc1F CHEMBL5268912 IC50 7.35 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2ccco2)cc(C(C)C)c1OCC(F)F CHEMBL130317 EC50 7.4 nM
CCCCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(F)(F)C(F)(F)F)cc1C(C)C CHEMBL424269 EC50 7.4 nM
CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl CHEMBL2022125 EC50 7.4 nM
CCCCCS(=O)(=O)NC(=O)CCc1cc(OCCCC)nn1Cc1ccc(Cl)cc1Cl CHEMBL1933829 EC50 7.5 nM
CCO[C@@H](Cc1ccc(OCCN2CCC(C)(C)c3cc(/C(=N/OCC4CC4)c4ccccc4)ccc32)cc1)C(=O)O CHEMBL537921 EC50 7.52 nM
C/C(=N\OCCF)C(Cc1ccc(OCc2nc(-c3ccc(F)cc3)oc2C)cc1)C(=O)O CHEMBL230410 EC50 7.7 nM
COc1ccc2c(-n3c(=O)n(Cc4cc([C@@]5(C)OC(=O)NC5=O)ccc4Cl)c4cc(C(F)(F)F)ccc43)noc2c1 CHEMBL1947142 IC50 7.7 nM
CN(CCOc1ccc(CC(Nc2ccccc2C(=O)C2CCCCCC2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146821 Log EC50 7.762 nM
CCO[C@@H](Cc1ccc(OCCN2CCC(C)(C)c3cc(/C(=N/OC)c4ccccc4)ccc32)cc1)C(=O)O CHEMBL565198 EC50 7.85 nM
CC[C@@H](NC(=O)c1ccc2c(c1)ncn2Cc1ccccc1F)c1ccccc1 CHEMBL1825122 pEC50 7.943 nM
Cc1cc(Oc2ccc(F)c(CNC(=O)c3ccc(C(F)(F)F)cc3F)c2)ccc1OC(C)(C)C(=O)O CHEMBL237520 pIC50 7.998 nM
COc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(C)(C)C(=O)O)c(C)c3)c2)c(C)c1 CHEMBL237306 pIC50 7.998 nM
Cc1cc(Oc2cccc(CNC(=O)c3cc4cc(Br)ccc4[nH]3)c2)ccc1CCC(=O)O CHEMBL237485 pIC50 7.998 nM
Cc1cc(Oc2cc(F)cc(CNC(=O)c3ccc(C(F)(F)F)cc3F)c2)ccc1OC(C)(C)C(=O)O CHEMBL392717 pIC50 7.998 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL82034 EC50 8.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c2c1CCN(C(=O)OCC(C)C)C2 CHEMBL446365 EC50 8.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)OC(C)C)c1 CHEMBL219824 EC50 8.0 nM
CCCOC(=O)N1C=C(Cc2cccc(OCCc3nc(-c4ccccc4)oc3C)c2)C(C(=O)O)CC1 CHEMBL256142 EC50 8.0 nM
CO[C@@H](Cc1ccc(OCCc2nc(-c3cc(C)cc(C)c3)oc2C)c2ccsc12)C(=O)O CHEMBL484138 IC50 8.0 nM
Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc(C[C@H](OCC(F)(F)F)C(=O)O)c2ccccc12 CHEMBL508299 IC50 8.0 nM
Cc1cc(CNC(=O)c2cc(-c3ccc(C(C)C)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O CHEMBL455157 EC50 8.0 nM
Cc1cc(CNC(=O)c2cc(-c3ccc(CC(C)C)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O CHEMBL454678 EC50 8.0 nM
COc1ccc2c(-n3c(=O)n(Cc4cc(O[C@H](C)C(=O)O)ccc4Cl)c4ccccc43)noc2c1 CHEMBL1947146 EC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](c3cccc(C(C)C)c3)C3CC3)cc12 CHEMBL3736463 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@H](c3cccc(C(C)C)c3)C3CC3)cc12 CHEMBL3695863 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(F)c3)cc12 CHEMBL3695881 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)C)cc3)cc12 CHEMBL3695886 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cc(C4CC4)ccn3)cc12 CHEMBL3699409 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@H](C)c3ccnc(Br)c3)cc12 CHEMBL3699412 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3cncc(Br)c3)cc12 CHEMBL3699418 IC50 8.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3cc(F)c(F)cc3F)cc12 CHEMBL3699428 IC50 8.0 nM
COc1cc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2cccc(C(F)(F)F)c2)ccc1O CHEMBL4558373 Ki 8.0 nM
CCCCCS(=O)(=O)NC(=O)/C=C/c1cc(C(C)C)nn1Cc1ccc(Cl)cc1Cl CHEMBL1933844 EC50 8.2 nM
CC(C)CCS(=O)(=O)NC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl CHEMBL1933842 EC50 8.3 nM
Cc1cc(N2CCOCC2)cnc1NC(=O)c1cc(C(=O)NCc2ccc(F)c(F)c2)c(F)cc1Cl CHEMBL5271038 IC50 8.3 nM
CCCCCS(=O)(=O)NC(=O)CCc1cc(C(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl CHEMBL1933834 EC50 8.4 nM
CC(/C=C/[C@@H]1C[C@]1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL75133 EC50 8.6 nM
COCCOc1ccc(CCC(=O)NS(=O)(=O)c2ccc(Cl)cc2)c(Oc2ncc(C(F)(F)F)cc2Cl)c1 CHEMBL2024605 EC50 8.6 nM
CCc1ccc(-c2nc3cc(NC(=O)c4cc(C#N)ccc4Cl)ccc3o2)cc1 CHEMBL5173312 IC50 8.6 nM
CN(CCOc1ccc(CC(Nc2ccc(Cl)cc2C(=O)c2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 CHEMBL146258 Log Ki 8.71 nM
COc1cc(CCC[C@H]2OC(=O)NC2=O)ccc1OCc1nc(-c2ccco2)oc1C CHEMBL4639604 EC50 8.87 nM
CCCc1c(OCCCCOc2ccc(CCC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 CHEMBL172931 Ki 8.9 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(C(F)(F)F)cc3C)c2)ccc1OC(C)(C)C(=O)O CHEMBL236664 pIC50 8.995 nM
Cc1cc(Oc2cccc(CNC(=O)c3ccc(Cl)cc3C)c2)ccc1OC(C)(C)C(=O)O CHEMBL237086 pIC50 8.995 nM
Cc1oc(C2CCCCC2)nc1CCOc1ccc(CC(C)(Oc2ccccc2)C(=O)O)cc1 CHEMBL309882 EC50 9.0 nM
CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1 CHEMBL378068 EC50 9.0 nM
Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc(CCC(=O)O)c2c1CCN(C(=O)OCC(C)(C)C)C2 CHEMBL387373 EC50 9.0 nM
Cc1oc(-c2ccccc2)nc1CCOc1cccc(CC2=CN(C(=O)OCC(C)C)CCC2C(=O)O)c1 CHEMBL256358 EC50 9.0 nM
COc1ccc(C(=O)c2c(C)n(Cc3cccc(O[C@@H](C)C(=O)O)c3)c3nc(C)ccc23)cc1 CHEMBL510180 EC50 9.0 nM
CCO[C@@H](Cc1ccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)c2ccsc12)C(=O)O CHEMBL484000 EC50 9.0 nM
COCCOc1cc(/C=C/C(=O)NS(=O)(=O)CCC(C)C)n(Cc2ccc(C(F)(F)F)cc2Cl)n1 CHEMBL1933843 EC50 9.0 nM
CCOC(=O)N1C[C@@H](Cc2cccc(OCCc3nc(-c4ccccc4)oc3C)c2)[C@@H](C(=O)O)C1 CHEMBL3398436 EC50 9.0 nM
CC[C@H](NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1cccc(C(C)C)c1 CHEMBL3695916 IC50 9.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3cc(C(F)(F)F)ccc3C(F)(F)F)cc12 CHEMBL3695893 IC50 9.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3cccc(F)c3F)cc12 CHEMBL3699375 IC50 9.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(F)c(F)c3)cc12 CHEMBL3699379 IC50 9.0 nM
Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3c(F)cccc3C(F)(F)F)cc12 CHEMBL3699427 IC50 9.0 nM
C[C@@H](NC(=O)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1)c1ccc(Br)cc1 CHEMBL3678085 IC50 9.0 nM
COc1ccc2c(-n3c(=O)n(Cc4cc(O[C@H](C)C(=O)O)ccc4Cl)c4cc(C(F)(F)F)ccc43)noc2c1 CHEMBL1946953 IC50 9.1 nM
CCCOc1ccc(C[C@H](CCc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 CHEMBL2158959 EC50 9.2 nM
CCCCCS(=O)(=O)NC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl CHEMBL1933841 EC50 9.3 nM
O=C(c1ccccc1)c1ccccc1N[C@@H](Cc1ccc(OCCc2ccc(Cl)cc2)cc1)C(=O)O CHEMBL149605 Log Ki 9.333 nM