N#C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CCCc1ccccc1 CHEMBL189620 Ki 0.023 nM
O=C(c1cc(-c2ccccc2)on1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 CHEMBL97152 Ki 0.21 nM
O=C(c1ccsn1)C1CCCN1C(=O)C1CCCN1C(=O)OCc1ccccc1 CHEMBL95698 Ki 0.26 nM
O=C(c1cc(COCc2ccccc2)on1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 CHEMBL318284 Ki 0.28 nM
O=C(c1cc(COCc2ccccc2)on1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CCCc1ccccc1 CHEMBL318630 Ki 0.34 nM
O=C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 CHEMBL79993 Ki 0.4 nM
O=C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CC1Cc2ccccc2C1 CHEMBL302654 IC50 0.42 nM
C[Si](C)(C)c1cc(C(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)no1 CHEMBL99305 Ki 0.45 nM
O=C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)C[C@H]1CCc2ccccc2C1 CHEMBL65284 IC50 0.45 nM
O=C[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)C[C@H]1CCc2ccccc2C1 CHEMBL291393 IC50 0.46 nM
O=CC1CSCN1C(=O)C1CSCN1C(=O)OCc1ccccc1 CHEMBL22766 IC50 0.5 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)C[C@H]1CCc2ccccc2C1 CHEMBL63745 IC50 0.52 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)C[C@H]1CCc2ccccc2C1 CHEMBL294367 IC50 0.55 nM
CC(C)[C@H](NC(=O)c1cccnc1)C(=O)N1CCC[C@H]1B(O)O CHEMBL2333024 Ki 0.73 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC=C[C@H]2CN(Cc3ccccc3)C(=O)[C@@H]21 CHEMBL3817958 Ki 0.75 nM
O=C[C@@H]1CSCN1C(=O)[C@@H]1CSCN1C(=O)C[C@H]1CCc2ccccc2C1 CHEMBL65512 IC50 0.85 nM
O=C([C@@H]1CCCN1C(=O)CCCc1ccccc1)N1CCCC1 CHEMBL289651 Ki 0.97 nM
O=C[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1 CHEMBL65338 IC50 1.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccccc2I)n1 CHEMBL4758377 IC50 1.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(Cl)cc2Cl)n1 CHEMBL4762591 IC50 1.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(CSc2ccc(Cl)c(Cl)c2)n1 CHEMBL4746891 IC50 1.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1 CHEMBL66088 IC50 1.1 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CC1Cc2ccccc2C1 CHEMBL62580 IC50 1.2 nM
CC(C)[C@H](NC(=O)c1ccncc1)C(=O)N1CCC[C@H]1B(O)O CHEMBL4464623 IC50 1.3 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)[C@@H]1C[C@H]1c1ccccc1)N1CCSC1 CHEMBL1086968 Ki 1.5 nM
O=C(CCC(=O)N1CCC[C@H]1B(O)O)c1ccccc1 CHEMBL217802 Ki 1.7 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1cccnc1 CHEMBL2333023 IC50 1.8 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1cccc2ccccc12 CHEMBL1243373 IC50 1.8 nM
CC(=O)c1cc(OCCc2ccccc2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL515482 IC50 2.0 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1cc(Cl)ccc1Cl CHEMBL386890 Ki 2.2 nM
O=C([C@@H]1CSCN1C(=O)C[C@H]1CCc2ccccc2C1)N1CCSC1 CHEMBL304644 IC50 2.3 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)C1CCCC1 CHEMBL217244 Ki 2.3 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)C1CCCCC1 CHEMBL387444 Ki 2.7 nM
O=C1c2ccccc2CN1CC(=O)N1CCC[C@H]1B(O)O CHEMBL387050 Ki 2.8 nM
CC(=O)c1cc(OCCc2ccc(F)cc2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL476508 IC50 3.0 nM
C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C#N CHEMBL1079410 IC50 3.0 nM
O=C([C@H]1CCCN1C(=O)C[C@H]1CCc2ccccc2C1)N1CCSC1 CHEMBL65109 IC50 3.4 nM
O=C[C@@H]1CCCN1C(=O)c1cccc2c1C(=O)N(Cc1ccccc1)C2 CHEMBL4451993 Ki 3.5 nM
O=C([C@@H]1CSCN1C(=O)C[C@H]1CCc2ccccc2C1)N1CCCC1 CHEMBL66257 IC50 4.0 nM
O=C([C@@H]1CCc2c(S(=O)(=O)c3ccccc3)cc(OCc3cc(F)cc(F)c3)c(=O)n21)N1CCCC1 CHEMBL476950 IC50 4.0 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1c(Cl)cccc1Cl CHEMBL443836 Ki 4.4 nM
CC(C)C(=O)NCC(=O)N1CCC[C@H]1B(O)O CHEMBL216410 Ki 4.5 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@@H]1C[C@@H]1c1cccs1)N1CCCC1 CHEMBL307938 IC50 4.8 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCCC(c1ccccc1)C(F)(F)F)N1CCCC1 CHEMBL308073 IC50 5.0 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1ccncc1 CHEMBL2333025 IC50 5.0 nM
COc1ccc(Cc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4748328 IC50 5.0 nM
O=C([C@H]1CCCN1C(=O)C[C@H]1CCc2ccccc2C1)N1CCCC1 CHEMBL63045 IC50 5.4 nM
NC(N)=NCCC[C@@H](N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)NC(Cc1cccs1)C(=O)N[C@@H](CO)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N1c2ccccc2C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O CHEMBL2369824 IC50 5.5 nM
CC(C)(C)OC(=O)N1C2CCC(C2)[C@@H]1C(=O)N1CCCC1 CHEMBL78877 IC50 5.5 nM
O=C(C1=NOC(COCc2ccccc2)C1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 CHEMBL273161 Ki 6.0 nM
N#C[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)CCCc1ccccc1 CHEMBL2024671 IC50 6.0 nM
COc1cc(NC(C)=O)ccc1C(=O)N1CCC[C@H]1B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1 CHEMBL4559324 Ki 6.0 nM
O=C([C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1)N1CCSC1 CHEMBL66258 IC50 6.5 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)CCCc1ccccc1)N1CCCC1 CHEMBL335796 IC50 7.0 nM
CC(=O)c1cc(OCc2ccc(F)c(F)c2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL477998 IC50 7.0 nM
CN(CC(=O)N1CCC[C@H]1B(O)O)C(=O)c1ccccc1 CHEMBL385419 Ki 7.4 nM
N#Cc1cc(C(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)no1 CHEMBL100213 Ki 7.5 nM
CC(=O)c1cc(OCc2ccc(F)c(Cl)c2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL478199 IC50 8.0 nM
O=C([C@H]1CCCN1C(=O)CC1Cc2ccccc2C1)N1CCSC1 CHEMBL64240 IC50 8.7 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)CCCC(C1CC1)C1CC1)N1CCCC1 CHEMBL76303 IC50 9.0 nM
CC1CCC(CC(=O)N2Cc3ccccc3C[C@H]2C(=O)N2CCCC2)CC1 CHEMBL139862 IC50 9.0 nM
CSc1ccccc1C(=O)N1CCC[C@H]1B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1 CHEMBL4576969 Ki 9.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccccc2Br)n1 CHEMBL4751873 IC50 9.0 nM
O=C([C@@H]1CSCN1C(=O)CC1Cc2ccccc2C1)N1CCCC1 CHEMBL62960 IC50 10.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC=C[C@H]2CN(OCc3ccccc3)C(=O)[C@@H]21 CHEMBL3818013 Ki 10.0 nM
O=C([C@@H]1CCc2c(S(=O)(=O)c3ccccc3)cc(OCc3ccc(C(F)(F)F)cc3)c(=O)n21)N1CCCC1 CHEMBL476951 IC50 11.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)C)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H]4CCCN4C(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CSSC[C@@H](C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc4ccccc4)NC1=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N2 CHEMBL4796244 IC50 11.0 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1ccnc2ccccc12 CHEMBL3233847 IC50 11.2 nM
O=C([C@@H]1CCc2c(Cl)cc(NCc3ccccc3)c(=O)n21)N1CCCC1 CHEMBL514702 IC50 12.0 nM
CC(C)C(=O)N(C)CC(=O)N1CCC[C@H]1B(O)O CHEMBL216376 Ki 13.0 nM
O=C([C@@H]1C2CCC(C2)N1C(=O)[C@@H]1C[C@@H]1c1ccccc1)N1CCCC1 CHEMBL78421 IC50 14.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)CCCCc1ccccc1)N1CCCC1 CHEMBL422281 IC50 14.0 nM
O=C([C@@H]1CCc2c(Cl)cc(NCc3ccc(F)c(F)c3)c(=O)n21)N1CCCC1 CHEMBL476985 IC50 15.0 nM
O=C(c1nccs1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1OCc1ccccc1 CHEMBL269822 Ki 16.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2cc(Cl)ccc2Cl)n1 CHEMBL4792518 IC50 16.0 nM
O=C([C@H]1CCCN1C(=O)CC1Cc2ccccc2C1)N1CCCC1 CHEMBL262241 IC50 17.0 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCCC(C1CC1)C1CC1)N1CCCC1 CHEMBL77088 IC50 17.0 nM
Cc1cc(Cl)ccc1OCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1 CHEMBL342718 IC50 17.0 nM
O=C([C@@H]1CCc2c(Cl)cc(NCc3ccc(F)cc3)c(=O)n21)N1CCCC1 CHEMBL515786 IC50 17.0 nM
O=C([C@@H]1CSCN1C(=O)CC1CCc2sccc2C1)N1CCCC1 CHEMBL304020 IC50 18.0 nM
O=C([C@@H]1CCc2ccc(OCc3ccc(F)c(F)c3)c(=O)n21)N1CCCC1 CHEMBL478844 IC50 18.0 nM
CC(C)(C)OC(=O)N1C2CCC(CC2)[C@@H]1C(=O)N1CC=CC1 CHEMBL310809 IC50 20.0 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)CCCC=C(C1CC1)C1CC1)N1CCCC1 CHEMBL79079 IC50 20.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)OCc1ccccc1 CHEMBL1079579 IC50 20.0 nM
O=C[C@@H]1CCCN1C(=O)CNC(=O)OCc1ccccc1 CHEMBL5282548 IC50 20.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)Cc1ccc(C(F)(F)F)cc1)N1CCCC1 CHEMBL342651 IC50 21.0 nM
O=C(NCCCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1)OCc1ccccc1 CHEMBL138674 IC50 21.0 nM
O=C([C@@H]1CCc2ccc(OCc3cc(F)cc(F)c3)c(=O)n21)N1CCCC1 CHEMBL478843 IC50 22.0 nM
O=C([C@@H]1CCc2ccc(OCc3ccc(F)cc3)c(=O)n21)N1CCCC1 CHEMBL518279 IC50 22.0 nM
CC(=O)c1cc(OCc2cc(F)cc(F)c2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL516746 IC50 22.0 nM
CC1(C)[C@H]2C[C@@H]3OB([C@@H]4CCCN4C(=O)c4cccc5c4C(=O)N(Cc4ccccc4)C5)O[C@]3(C)[C@@H]1C2 CHEMBL4558566 Ki 22.0 nM
CC(C)(C)OC(=O)N1C2CCC(CC2)[C@@H]1C(=O)N1CCCC1 CHEMBL311876 IC50 23.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)[C@H]1C[C@@H]1c1ccccc1)N1CCCC1 CHEMBL139696 IC50 23.0 nM
N#C[C@@H]1CCCN1C(=O)c1cccc2c1C(=O)N(Cc1ccccc1)C2 CHEMBL2159748 Ki 23.0 nM
O=C([C@@H]1CSCN1C(=O)C[C@@H]1CCc2ccccc2C1)N1CCSC1 CHEMBL63133 IC50 24.0 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)CC/C=C/C(C1CC1)C1CC1)N1CCCC1 CHEMBL80557 IC50 24.0 nM
CC(C)(C)OC(=O)N1C2CCC(CC2)[C@@H]1C(=O)N1CCSC1 CHEMBL311879 IC50 24.0 nM
CC(=O)CCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1 CHEMBL423002 IC50 25.0 nM
O=C(NCC(=O)N1CCC[C@H]1B(O)O)c1ccccc1 CHEMBL217753 Ki 25.0 nM
O=C([C@@H]1C2CCC(C2)N1C(=O)CCCC(C1CC1)C1CC1)N1CCCC1 CHEMBL76679 IC50 26.0 nM
O=C[C@@H]1CCCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 CHEMBL1173095 IC50 26.0 nM
CSCC[C@@H](NC(=O)c1ccnc2ccccc12)C(=O)N1CCC[C@H]1B(O)O CHEMBL2332621 IC50 26.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccccc2-c2ccc3ccccc3c2)n1 CHEMBL4750058 IC50 26.0 nM
O=C([C@H]1C2CCC(C2)N1C(=O)CCCc1ccccc1)N1CCCC1 CHEMBL312332 IC50 27.0 nM
CC(=O)c1cc(OCc2ccc(Cl)c(Cl)c2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL476949 IC50 28.0 nM
CC(=O)c1cc(OCc2ccc(C(F)(F)F)cc2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL477776 IC50 28.0 nM
CC(C)(C)OC(=O)N1C(C(=O)N2CCC2)C[C@@H]2CCCC[C@@H]21 CHEMBL312371 IC50 30.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3cccc(Cl)c3)c(=O)n21)N1CCCC1 CHEMBL478446 IC50 30.0 nM
O=C([C@@H]1CCc2ccc(OCc3ccc(F)cc3F)c(=O)n21)N1CCCC1 CHEMBL477338 IC50 31.0 nM
CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCCC1 CHEMBL311364 IC50 32.0 nM
O=C1[C@H]2[C@@H](C=CC[C@H]2C(=O)N2CCCC2)CN1Cc1ccccc1 CHEMBL3818020 Ki 32.5 nM
O=C([C@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCCc1ccccc1)N1CCCC1 CHEMBL79002 IC50 34.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3ccc(Cl)c(Cl)c3)c(=O)n21)N1CCCC1 CHEMBL478610 IC50 34.0 nM
O=C([C@@H]1CCc2ccc(OCc3ccc(C(F)(F)F)cc3)c(=O)n21)N1CCCC1 CHEMBL515168 IC50 34.0 nM
O=C(c1ccon1)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 CHEMBL99237 Ki 36.0 nM
O=C([C@@H]1CSCN1C(=O)CCC1Cc2ccccc2C1)N1CCCC1 CHEMBL303066 IC50 36.0 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)C[C@H](c1ccccc1)C(F)(F)F)N1CCCC1 CHEMBL2115184 IC50 36.0 nM
O=C(NCCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1)OCc1ccccc1 CHEMBL136325 IC50 36.0 nM
O=C([C@@H]1CSCN1C(=O)C[C@@H]1CCc2ccccc2C1)N1CCCC1 CHEMBL63994 IC50 38.0 nM
O=C([C@H]1CCCN1C(=O)C[C@@H]1CCc2ccccc2C1)N1CCSC1 CHEMBL63537 IC50 40.0 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)CCCCC(C1CC1)C1CC1)N1CCCC1 CHEMBL307251 IC50 40.0 nM
N#Cc1ccc(OC[C@H]2CC[C@@H](C(=O)N3CCC[C@H]3C#N)N2)c(Cl)c1 CHEMBL209940 Ki 40.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3cc(F)cc(F)c3F)c(=O)n21)N1CCCC1 CHEMBL478233 IC50 40.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3ccc(F)cc3)c(=O)n21)N1CCCC1 CHEMBL478609 IC50 40.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3ccc(F)c(Cl)c3)c(=O)n21)N1CCCC1 CHEMBL516744 IC50 43.0 nM
C[C@H](NC(=O)c1ccnc2ccccc12)C(=O)N1CCC[C@H]1C#N CHEMBL3233540 IC50 44.0 nM
COc1ccccc1C(=O)N1CCC[C@H]1B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1 CHEMBL4579992 Ki 44.0 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCCC(C1CCCC1)C(F)(F)F)N1CCCC1 CHEMBL80629 IC50 46.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)CN[C@H]1[C@@H]2CN(c3ncccn3)C[C@@H]21 CHEMBL482261 IC50 46.0 nM
C[C@H]1C=C[C@H]2CN(Cc3ccccc3)C(=O)[C@@H]2[C@@H]1C(=O)N1CCC[C@H]1C#N CHEMBL3819136 Ki 46.0 nM
O=C([C@H]1CCCN1C(=O)C[C@@H]1CCc2ccccc2C1)N1CCCC1 CHEMBL292302 IC50 48.0 nM
CC(=O)c1cc(OCc2ccc(Cl)cc2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL476943 IC50 48.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(F)cc2Cl)n1 CHEMBL4785892 IC50 48.0 nM
CS(=O)(=O)c1ccc(Cc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4797479 IC50 48.0 nM
COc1cccc(F)c1C(=O)N1CCC[C@H]1B1O[C@@H]2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1 CHEMBL4474217 Ki 49.0 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@@H]1C[C@@H]1c1ccccc1)N1CCCC1 CHEMBL80499 IC50 50.0 nM
O=C([C@H]1C2CCC(CC2)N1C(=O)CCCc1ccccc1)N1CCCC1 CHEMBL78935 IC50 50.0 nM
N#Cc1ccc(CCCc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4781018 IC50 51.0 nM
CC(=O)N(C)CC(=O)N1CCC[C@H]1B(O)O CHEMBL217754 Ki 53.0 nM
CC(=O)c1cc(OCc2ccc(F)cc2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL477775 IC50 53.0 nM
O=C([C@@H]1Cc2ccccc2CN1C(=O)Cc1cccs1)N1CCCC1 CHEMBL334569 IC50 54.0 nM
CC(C)(C)OC(=O)NCCCCCC(=O)N1Cc2ccccc2C[C@H]1C(=O)N1CCCC1 CHEMBL341749 IC50 55.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3ccc(F)c(F)c3)c(=O)n21)N1CCCC1 CHEMBL514397 IC50 55.0 nM
O=C(N[C@@H](C(=O)N1CCC[C@H]1B(O)O)c1ccccc1)c1ccnc2ccccc12 CHEMBL2333022 IC50 57.0 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCC(C1CC1)C1CC1)N1CCCC1 CHEMBL76680 IC50 58.0 nM
O=C([C@@H]1CSCN1C(=O)CCCC1Cc2ccccc2C1)N1CCCC1 CHEMBL416866 IC50 60.0 nM
CC(C)(C)c1ccc(COc2ccc3n(c2=O)[C@H](C(=O)N2CCCC2)CC3)cc1 CHEMBL477337 IC50 60.0 nM
CSc1ccc(Cc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4762306 IC50 60.0 nM
O=C([C@@H]1CCc2ccc(OCc3cc(F)ccc3F)c(=O)n21)N1CCCC1 CHEMBL514385 IC50 64.0 nM
N#C[C@@H]1CCCN1C(=O)c1ccccc1C(=O)NCc1ccccc1 CHEMBL2159745 IC50 65.0 nM
O=C([C@H]1CCCN1C(=O)CC1=Cc2ccccc2C1)N1CCCC1 CHEMBL65373 IC50 69.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCC3CCCCC3)c(=O)n21)N1CCCC1 CHEMBL478232 IC50 70.0 nM
N#Cc1ccc(OCc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4747575 IC50 70.0 nM
CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O CHEMBL67279 IC50 73.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(-n3cccn3)cc2)n1 CHEMBL4742308 IC50 76.0 nM
N#Cc1ccc(S(=O)(=O)Cc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4789965 IC50 77.0 nM
O=C([C@@H]1C2CCC(C2)N1C(=O)[C@H]1C[C@H]1c1ccccc1)N1CCCC1 CHEMBL78665 IC50 78.0 nM
O=C([C@@H]1CCc2c(Cl)cc(NCCc3ccccc3)c(=O)n21)N1CCCC1 CHEMBL477609 IC50 80.0 nM
CC(=O)Nc1ccc(C(=O)N2CCC[C@H]2B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)c(F)c1 CHEMBL4529691 Ki 80.0 nM
O=C(C1CCCN1C(=O)OCc1ccccc1)N1CCCC1 CHEMBL23089 IC50 86.0 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCSC(C1CC1)C1CC1)N1CCCC1 CHEMBL312560 IC50 86.0 nM
CC[C@@H](NC(=O)c1ccnc2ccccc12)C(=O)N1CCC[C@H]1B(O)O CHEMBL2332622 IC50 96.0 nM
CN(CC(=O)N1CCC[C@H]1B(O)O)C(=O)C1CCC(=O)N1 CHEMBL217056 Ki 101.0 nM
N#Cc1ccc(-c2ccc(Cc3nc(C(=O)NCC(=O)N4CC(F)(F)C[C@H]4C#N)cs3)cc2)cc1 CHEMBL4753316 IC50 103.0 nM
Cc1ccc(Cc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4779526 IC50 107.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1cccc(-c2ccc(Cl)cc2)n1 CHEMBL4799547 IC50 108.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(Br)cc2)n1 CHEMBL4746868 IC50 108.0 nM
CCCC[C@@H](NC(=O)c1ccnc2ccccc12)C(=O)N1CCC[C@H]1B(O)O CHEMBL2332624 IC50 110.0 nM
COC(OC)C1CCCN1C(=O)C1CCCN1C(=O)OCc1ccccc1 CHEMBL280385 IC50 120.0 nM
Cc1ccc(SCc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4780357 IC50 121.0 nM
O=C([C@@H]1CSCN1C(=O)Cc1cc2ccccc2s1)N1CCCC1 CHEMBL293168 IC50 130.0 nM
O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@H]1C[C@H]1c1ccccc1)N1CCCC1 CHEMBL310381 IC50 130.0 nM
CC(=O)N[C@H](C)C(=O)N1CCC[C@H]1B(O)O CHEMBL387462 IC50 130.0 nM
N#CC1CCCN1C(=O)CNC(=O)c1cncc2ccccc12 CHEMBL3914236 IC50 130.0 nM
N#Cc1ccc(SCc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4748680 IC50 138.0 nM
COc1ccc(COc2cc(C(C)=O)c3n(c2=O)[C@H](C(=O)N2CCCC2)CC3)cc1 CHEMBL476734 IC50 140.0 nM
O=C([C@@H]1CSCN1C(=O)CC1CCCc2ccccc2C1)N1CCCC1 CHEMBL413107 IC50 150.0 nM
O=C([C@@H]1CSCN1C(=O)[C@H]1C[C@H]1c1ccccc1)N1CCCC1 CHEMBL311120 IC50 150.0 nM
O=C(c1cccc2c1C(=O)N(Cc1ccccc1)C2)N1CCCC1 CHEMBL2159749 IC50 150.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(CS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL4758299 IC50 151.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(-c2ccc(Cl)cc2C(F)(F)F)n1 CHEMBL4762435 IC50 154.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2cccc(Br)c2)n1 CHEMBL4755802 IC50 159.0 nM
Cc1ccc(S(=O)(=O)Cc2nc(C(=O)NCC(=O)N3CC(F)(F)C[C@H]3C#N)cs2)cc1 CHEMBL4759201 IC50 163.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)c1cccc2c1C(=O)N(Cc1ccccc1)C2 CHEMBL4462021 Ki 170.0 nM
CS(=O)(=O)c1ccc(OC[C@H]2CC[C@@H](C(=O)N3CCC[C@H]3C#N)N2)c(Cl)c1 CHEMBL210805 Ki 178.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(Cl)cc2)n1 CHEMBL4789754 IC50 182.0 nM
CC(C)(C)C(=O)NCC(=O)N1CCC[C@H]1B(O)O CHEMBL216411 Ki 191.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1cnc(-c2ccc(Cl)cc2)cn1 CHEMBL4782931 IC50 197.0 nM
N#C[C@@H]1CS[C@H]2C[C@@H](NC(=O)OCc3ccccc3)C(=O)N12 CHEMBL1079474 IC50 200.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(OC(F)(F)F)cc2)n1 CHEMBL4744633 IC50 200.0 nM
CC(=O)Nc1ccc(C(=O)N2CCC[C@H]2B(O)O)c(F)c1 CHEMBL4434935 Ki 210.0 nM
CC(=O)NCC(=O)N1CCC[C@H]1B(O)O CHEMBL217561 Ki 211.0 nM
CC(C)c1cc(C(=O)O)ccc1OC[C@H]1CC[C@@H](C(=O)N2CCC[C@H]2C#N)N1 CHEMBL436744 Ki 245.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3ccc(C(F)(F)F)cc3)c(=O)n21)N1CCCC1 CHEMBL516284 IC50 250.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(COc2ccc(Cl)c(Cl)c2)n1 CHEMBL4754490 IC50 269.0 nM
CC(C)(C)c1ccc(COc2cc(S(=O)(=O)c3ccccc3)c3n(c2=O)[C@H](C(=O)N2CCCC2)CC3)cc1 CHEMBL516410 IC50 270.0 nM
CC(=O)Nc1ccc(C(=O)N2CCC[C@H]2B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)cc1 CHEMBL4451076 Ki 270.0 nM
N#C[C@@H]1C[C@H](F)CN1C(=O)CNC(=O)c1ccnc2ccccc12 CHEMBL3233840 IC50 290.0 nM
O=C(c1cccc2c1C(=O)N(Cc1ccccc1)C2)N1CC[C@H](F)C1 CHEMBL4437462 Ki 290.0 nM
CCC[C@@H](NC(=O)c1ccnc2ccccc12)C(=O)N1CCC[C@H]1B(O)O CHEMBL2332623 IC50 320.0 nM
CC(=O)c1cc(OCc2ccc(F)cc2)c(=O)n2c1CC[C@H]2C(=O)n1cccc1 CHEMBL478632 IC50 343.0 nM
COC(OC)C1CSCN1C(=O)C1CCCN1C(=O)OCc1ccccc1 CHEMBL277257 IC50 350.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2c(Cl)cccc12 CHEMBL2385274 IC50 350.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1cc(O)nc2ccccc12 CHEMBL2385295 IC50 350.0 nM
O=C(Cn1ccccc1=O)N1CCC[C@H]1B(O)O CHEMBL383855 Ki 353.0 nM
CC1(C)[C@@H]2C[C@H]3OB([C@@H]4CCCN4C(=O)c4c(F)cccc4F)O[C@@]3(C)[C@H]1C2 CHEMBL4438065 Ki 355.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2c(Br)cccc12 CHEMBL2385275 IC50 360.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2cc(C(=O)O)ccc2Cl)N1 CHEMBL378867 Ki 368.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(CS(=O)(=O)c2ccc(Cl)c(Cl)c2)n1 CHEMBL4791505 IC50 368.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(CCCc2ccc(Cl)c(Cl)c2)n1 CHEMBL4743736 IC50 387.0 nM
N#Cc1ccc(N2C[C@@H]3[C@H](C2)[C@H]3NCC(=O)N2C[C@@H](F)C[C@H]2C#N)c(Cl)c1 CHEMBL481669 IC50 392.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(-n3cncn3)cc2)n1 CHEMBL4761499 IC50 410.0 nM
N#Cc1c(Cl)cccc1N1C[C@@H]2[C@H](C1)[C@H]2NCC(=O)N1C[C@@H](F)C[C@H]1C#N CHEMBL479538 IC50 417.0 nM
O=C(OCc1ccccc1)N1CCCC1C(=O)N1CCCC1C1SCCS1 CHEMBL23690 IC50 420.0 nM
N#C[C@H]1CCCN1C(=O)CNC(=O)OCc1ccccc1 CHEMBL1079580 IC50 430.0 nM
O=C(N[C@H](CO)C(=O)N1CCC[C@H]1B(O)O)c1ccnc2ccccc12 CHEMBL2332620 IC50 440.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(-c3ccc(Cl)cc3)cc2)n1 CHEMBL4743815 IC50 464.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(Cc2ccc(F)c(F)c2)n1 CHEMBL4748332 IC50 474.0 nM
CC(=O)c1ccc(N2C[C@@H]3[C@H](C2)[C@H]3NCC(=O)N2C[C@@H](F)C[C@H]2C#N)cc1 CHEMBL480914 IC50 492.0 nM
Cc1ccc2c(C(=O)NCC(=O)N3CCC[C@H]3C#N)ccnc2c1 CHEMBL3233834 IC50 500.0 nM
[C-]#[N+][C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2cc(C)ccc12 CHEMBL3900683 IC50 500.0 nM
N#C[C@@H]1CC(F)(F)CN1C(=O)CNC(=O)c1csc(CSc2ccc(C(F)(F)F)cc2)n1 CHEMBL4776967 IC50 508.0 nM
O=C([C@H]1CCCN1C(=O)Cc1cc2ccccc2o1)N1CCCC1 CHEMBL304892 IC50 510.0 nM
O=C([C@@H]1CSCN1C(=O)C1Cc2ccccc2C1)N1CCCC1 CHEMBL62629 IC50 520.0 nM
CC(=O)c1cc(OCC(F)(F)F)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL514230 IC50 584.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)Cc1ccc(Cl)cc1 CHEMBL2022507 IC50 600.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)Cc1cccc2ccccc12 CHEMBL2385286 IC50 600.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1cncc2ccccc12 CHEMBL2385276 IC50 610.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccc(F)cc12 CHEMBL2385270 IC50 610.0 nM
O=C(c1cccc2c1C(=O)N(Cc1ccccc1)C2)N1CC[C@@H](F)C1 CHEMBL4584206 Ki 620.0 nM
Cn1cc(C(=O)NCC(=O)N2CC(F)(F)C[C@H]2C#N)cc1-c1ccc(Cl)cc1 CHEMBL4751194 IC50 624.0 nM
C[C@@H](NC(=O)c1ccncc1Cl)C(=O)N1CCC[C@H]1B(O)O CHEMBL2333030 IC50 640.0 nM
Cc1cc(C(=O)NCC(=O)N2CCC[C@H]2C#N)c2ccccc2n1 CHEMBL2385293 IC50 640.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2cc(C(=O)O)cnc2Cl)N1 CHEMBL377296 Ki 666.0 nM
O=C(OCc1ccccc1)N1CCCC1C(=O)N1CCCC1C1OCCO1 CHEMBL23114 IC50 700.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccc(OC(F)(F)F)cc12 CHEMBL2385302 IC50 710.0 nM
O=C([C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)CCC(c1ccccc1)C(F)(F)F)N1CCCC1 CHEMBL80953 IC50 720.0 nM
CC1(C)[C@@H]2C[C@H]3OB([C@@H]4CCCN4C(=O)c4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL4452429 Ki 767.0 nM
O=C(NCC(=O)N1CCC[C@H]1C(=O)CCl)c1ccnc2ccccc12 CHEMBL3233848 IC50 780.0 nM
CC(=O)c1cc(OCc2ccc(C#N)cc2)c(=O)n2c1CC[C@H]2C(=O)N1CCCC1 CHEMBL479250 IC50 783.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCc3ccncc3)c(=O)n21)N1CCCC1 CHEMBL478618 IC50 800.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccc(Cl)cc12 CHEMBL2385301 IC50 840.0 nM
N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2ccccc12 CHEMBL2385281 IC50 860.0 nM
O=C([C@@H]1CCc2c(Cl)cc(OCCc3ccc(F)cc3)c(=O)n21)N1CCCC1 CHEMBL478619 IC50 900.0 nM
N#C[C@@H]1CCCN1C(=O)[C@@H]1CC[C@H](COc2ccc(C(=O)O)c3ccccc23)N1 CHEMBL380090 Ki 925.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CC(=O)NCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H]2C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O CHEMBL4209844 IC50 950.0 nM
CC(=O)Nc1ccc(C(=O)N2CCC[C@H]2B(O)O)cc1 CHEMBL4531021 Ki 950.0 nM
O=C(c1cccs1)[C@H]1C2CCC(CC2)N1C(=O)CCCc1ccccc1 CHEMBL311534 IC50 960.0 nM
C[C@@H](NC(=O)c1ccncc1)C(=O)N1CCC[C@H]1B(O)O CHEMBL2333026 IC50 990.0 nM
C[C@H](N)C(=O)N1CCC[C@H]1B(O)O CHEMBL63860 IC50 1000.0 nM
O=C([C@@H]1CCc2c(Cl)cc(Oc3ccccc3)c(=O)n21)N1CCCC1 CHEMBL516588 IC50 1000.0 nM
C[C@@H](NC(=O)c1ccnc2ccccc12)C(=O)N1CCC[C@H]1B(O)O CHEMBL2332619 IC50 1000.0 nM
COc1ccc(-c2cc(C(=O)NCC(=O)N3CCC[C@H]3C#N)c3ccccc3n2)cc1 CHEMBL2385296 IC50 1000.0 nM
C[C@H]1C=C[C@H]2CN(Cc3ccccc3)C(=O)[C@@H]2[C@@H]1C(=O)N1CCCC1 CHEMBL3819096 Ki 1000.0 nM
CC1(C)[C@@H]2C[C@H]3OB([C@@H]4CCCN4C(=O)c4ccccc4F)O[C@@]3(C)[C@H]1C2 CHEMBL4452999 Ki 1000.0 nM