COc1cc2c(cc1-c1cnn3ccc(-c4ccnc5[nH]ccc45)cc13)CNC(CF)C2 CHEMBL4212424 IC50 2.7 nM
COc1cc2c(cc1-c1cnn3ccc(-c4ccnc5[nH]ccc45)cc13)CNCC2 CHEMBL4202753 IC50 2.8 nM
NCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL592030 pKi 3.162 nM
COc1cc2c(cc1-c1cnn3ccc(-c4ccnc5[nH]ccc45)cc13)CNC(C)C2 CHEMBL4208685 IC50 3.8 nM
COc1cc2c(cc1-c1cnn3ccc(-c4ccnc5[nH]ccc45)cc13)CN(C)C2 CHEMBL4206065 IC50 5.0 nM
COc1cc2c(cc1-c1cnn3ccc(-c4ccnc5[nH]ccc45)cc13)CNC2 CHEMBL4216507 IC50 6.5 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 16.7 nM
COc1cc2c(cc1-n1cnc3cnc(-c4ccnc5[nH]ccc45)cc31)CNC2 CHEMBL4208028 IC50 30.0 nM
NC1CCC(Nc2nccc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1966628 pKi 31.62 nM
CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc21 CHEMBL220241 pKi 31.62 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 CHEMBL4568087 IC50 37.0 nM
COc1cc2c(cc1-n1cnc3ccc(-c4ccnc5[nH]ccc45)cc31)CNC2 CHEMBL4213984 IC50 48.0 nM
NC(=O)Cn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL1985095 pKi 63.1 nM
COc1cc2c(cc1-n1cnc3ccc(-c4ccnc5[nH]ccc45)nc31)CNC2 CHEMBL4212934 IC50 65.0 nM
NCC1CCN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CC1 CHEMBL4637651 IC50 70.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3cc[nH]c3)csc12)Cc1ccccc1 CHEMBL3731795 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3ccc[nH]3)csc12)Cc1ccccc1 CHEMBL3727941 IC50 100.0 nM
Cc1ccsc1-c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729436 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3cn[nH]c3)csc12)Cc1ccccc1 CHEMBL3728749 IC50 100.0 nM
Clc1cccc2sc3c(N4CCNCC4)nc(-c4ccncc4)nc3c12 CHEMBL3731614 IC50 100.0 nM
NCCNc1nc(-c2ccncc2)nc2c1sc1cccc(Cl)c12 CHEMBL3728477 IC50 100.0 nM
Cc1cc(C)c2c(n1)sc1c(NC[C@H](C)N)nc(-c3ccncc3)nc12 CHEMBL3732860 IC50 100.0 nM
Cc1csc2c(NC[C@H](C)N)nc(-c3ccncc3)nc12 CHEMBL3727783 IC50 100.0 nM
Cc1csc2c(N3CCCNCC3)nc(-c3ccncc3)nc12 CHEMBL3727818 IC50 100.0 nM
Cc1csc2c(N3CCNCC3)nc(-c3ccncc3)nc12 CHEMBL3733186 IC50 100.0 nM
C[C@@H](N)CNc1nc(-c2ccncc2)nc2c1sc1cccc(Cl)c12 CHEMBL3728698 IC50 100.0 nM
C[C@H](N)CNc1nc(-c2ccncc2)nc2c1sc1cccc(Cl)c12 CHEMBL3729073 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c1sc1cccc(Cl)c12)Cc1ccccc1 CHEMBL3727488 IC50 100.0 nM
Clc1cccc2sc3c(N4CCCNCC4)nc(-c4ccncc4)nc3c12 CHEMBL3730030 IC50 100.0 nM
Cc1csc2c(NCCN)nc(-c3ccncc3)nc12 CHEMBL3730662 IC50 100.0 nM
CC(C)[C@H](N)CNc1nc(-c2ccncc2)nc2c(Br)csc12 CHEMBL3732347 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(Br)csc12)CC1CCCCC1 CHEMBL3730525 IC50 100.0 nM
NCCNc1nc(-c2ccncc2)nc2c(Br)csc12 CHEMBL3732082 IC50 100.0 nM
Brc1csc2c(N3CCNCC3)nc(-c3ccncc3)nc12 CHEMBL3732296 IC50 100.0 nM
Brc1csc2c(N[C@@H]3CCCNC3)nc(-c3ccncc3)nc12 CHEMBL3732849 IC50 100.0 nM
Cc1c(Br)sc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3728387 IC50 100.0 nM
Cc1c(Br)sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3731369 IC50 100.0 nM
Cc1sc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc2c1Br CHEMBL3728018 IC50 100.0 nM
Cc1sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1C CHEMBL3731903 IC50 100.0 nM
N[C@H](CNc1nc(-c2cn[nH]c2)nc2sc3c(c12)CCCC3)Cc1ccccc1 CHEMBL3731001 IC50 100.0 nM
Cc1n[nH]c(C)c1-c1nc(NCCN)c2c3c(sc2n1)CCCC3 CHEMBL3731958 IC50 100.0 nM
NCCNc1nc(-c2cn[nH]c2)nc2sc3c(c12)CCCC3 CHEMBL3728291 IC50 100.0 nM
C[C@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3733037 IC50 100.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccccc1 CHEMBL3730554 IC50 100.0 nM
NCCOc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3728395 IC50 100.0 nM
Cc1csc2nc(-c3ccncc3)nc(N3CCCNCC3)c12 CHEMBL3732514 IC50 100.0 nM
C[C@@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3 CHEMBL3731862 IC50 100.0 nM
C[C@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3 CHEMBL3728690 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3)Cc1ccccc1 CHEMBL3728988 IC50 100.0 nM
c1cc(-c2nc(N3CCCNCC3)c3c4c(sc3n2)CCCCC4)ccn1 CHEMBL3732944 IC50 100.0 nM
c1cc(-c2nc(N3CCNCC3)c3c4c(sc3n2)CCCCC4)ccn1 CHEMBL3732699 IC50 100.0 nM
NCCNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3 CHEMBL3728024 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCSC3)Cc1ccccc1 CHEMBL3733094 IC50 100.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCC1(C3)OCCO1)Cc1ccccc1 CHEMBL3730360 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCCC3)Cc1ccccc1 CHEMBL3732346 IC50 100.0 nM
Cc1c(C(N)=O)sc2nc(-c3ccncc3)nc(NC[C@@H](N)Cc3ccccc3)c12 CHEMBL3733036 IC50 100.0 nM
CC1CCc2c(sc3nc(-c4ccncc4)nc(NC[C@@H](N)Cc4ccccc4)c23)C1 CHEMBL3733184 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccc(O)c1 CHEMBL3729774 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cscn1 CHEMBL3729660 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccnc1 CHEMBL3728077 IC50 100.0 nM
Cc1ccccc1C[C@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3728968 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccccc1F CHEMBL3731344 IC50 100.0 nM
Cc1cccc(C[C@H](N)CNc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)c1 CHEMBL3727561 IC50 100.0 nM
COc1ccc(C[C@H](N)CNc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)cc1 CHEMBL3728978 IC50 100.0 nM
Cc1c(C(N)=O)sc2nc(-c3ccncc3)nc(NCCN)c12 CHEMBL3728584 IC50 100.0 nM
Cc1sc2nc(-c3ccncc3)nc(NCCN)c2c1C CHEMBL3728050 IC50 100.0 nM
CC(C)Cc1csc2nc(-c3ccncc3)nc(NC[C@H](C)N)c12 CHEMBL3730633 IC50 100.0 nM
CC(C)Cc1csc2nc(-c3ccncc3)nc(NCCN)c12 CHEMBL3731728 IC50 100.0 nM
NCCNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCCC3 CHEMBL3729159 IC50 100.0 nM
CC1CCc2c(sc3nc(-c4ccncc4)nc(NCCN)c23)C1 CHEMBL3727835 IC50 100.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3733121 IC50 100.0 nM
c1cc(-c2nc(N3C[C@@H]4C[C@H]3CN4)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3728576 IC50 100.0 nM
CN(CCN)c1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3728970 IC50 100.0 nM
c1cc(-c2nc(N3CCCNCC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3728973 IC50 100.0 nM
CNCCNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3728294 IC50 100.0 nM
NCCNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3729516 IC50 100.0 nM
C[C@H]1CN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CCN1 CHEMBL3732754 IC50 100.0 nM
CN1CCCN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CC1 CHEMBL3731825 IC50 100.0 nM
c1cc(-c2nc(N3CCNCC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3732444 IC50 100.0 nM
C[C@@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3732988 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2ccsc12)Cc1ccccc1 CHEMBL3728884 IC50 100.0 nM
C[C@H](N)CNc1nc(-c2ccncc2)nc2c(Br)csc12 CHEMBL3729331 IC50 100.0 nM
Cc1n[nH]c(C)c1-c1nc(N[C@@H]2CCNC2)c2c3c(sc2n1)CCCC3 CHEMBL3731552 IC50 100.0 nM
Cc1n[nH]c(C)c1-c1nc(N2CCCNCC2)c2c3c(sc2n1)CCCC3 CHEMBL3731624 IC50 100.0 nM
Cc1n[nH]c(C)c1-c1nc(N2CCNCC2)c2c3c(sc2n1)CCCC3 CHEMBL3732901 IC50 100.0 nM
c1n[nH]cc1-c1nc(N[C@@H]2CCNC2)c2c3c(sc2n1)CCCC3 CHEMBL3728079 IC50 100.0 nM
C[C@H](N)CNc1nc(-c2cn[nH]c2)nc2sc3c(c12)CCCC3 CHEMBL3730379 IC50 100.0 nM
c1n[nH]cc1-c1nc(N2CCCNCC2)c2c3c(sc2n1)CCCC3 CHEMBL3730408 IC50 100.0 nM
c1n[nH]cc1-c1nc(N2CCNCC2)c2c3c(sc2n1)CCCC3 CHEMBL3733303 IC50 100.0 nM
CCCC#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3728571 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C#Cc3ccccc3)csc12)Cc1ccccc1 CHEMBL3731091 IC50 100.0 nM
COC/C=C/c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729100 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3ccc(F)cc3)csc12)Cc1ccccc1 CHEMBL3731101 IC50 100.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2c(-c3ccn[nH]3)csc12)Cc1ccccc1 CHEMBL3733230 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3ccccc3)csc12)Cc1ccccc1 CHEMBL3728652 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3cc(C4CC4)[nH]n3)csc12)Cc1ccccc1 CHEMBL3732273 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccc[nH]3)csc12)Cc1ccccc1 CHEMBL3731132 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3cc[nH]c3)csc12)Cc1ccccc1 CHEMBL3731922 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccoc3)csc12)Cc1ccccc1 CHEMBL3728051 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccco3)csc12)Cc1ccccc1 CHEMBL3730052 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(Nc3ccccc3)csc12)Cc1ccccc1 CHEMBL3730660 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(Nc3ncccn3)csc12)Cc1ccccc1 CHEMBL3728045 IC50 100.0 nM
Fc1ccccc1Nc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3F)nc12 CHEMBL3732486 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(C#CCCO)csc12)Cc1ccccc1 CHEMBL3727522 IC50 100.0 nM
Cc1sc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc2c1C#CC(C)(C)O CHEMBL3729218 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(C#CC3(O)CCC3)csc12)Cc1ccccc1 CHEMBL3730412 IC50 100.0 nM
C[C@H](O)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3F)nc12 CHEMBL3729275 IC50 100.0 nM
CC(C)(O)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3F)nc12 CHEMBL3732519 IC50 100.0 nM
CC(C)(O)C#Cc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3727637 IC50 100.0 nM
CC(C)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3728744 IC50 100.0 nM
COC(C)(C)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3732477 IC50 100.0 nM
CC[C@](C)(O)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3728039 IC50 100.0 nM
CCC[C@H](O)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3731640 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C#Cc3ccccn3)csc12)Cc1ccccc1 CHEMBL3731386 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C#Cc3ccccc3F)csc12)Cc1ccccc1 CHEMBL3730471 IC50 100.0 nM
CC(C)(O)CC#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3728004 IC50 100.0 nM
CNCC#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3730839 IC50 100.0 nM
C[C@H](O)CC#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729746 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C#CCCF)csc12)Cc1ccccc1 CHEMBL3733187 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C#Cc3cscn3)csc12)Cc1ccccc1 CHEMBL3727682 IC50 100.0 nM
CCCNC(=O)c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3730158 IC50 100.0 nM
CCNC(=O)c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729854 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C(=O)NC3CC3)csc12)Cc1ccccc1 CHEMBL3730262 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(/C=C/C(=O)O)csc12)Cc1ccccc1 CHEMBL3732295 IC50 100.0 nM
C#Cc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3731136 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-n3cccn3)csc12)Cc1ccccc1 CHEMBL3732972 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-n3ccnn3)csc12)Cc1ccccc1 CHEMBL3729698 IC50 100.0 nM
Nc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729527 IC50 100.0 nM
Cc1cc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)no1 CHEMBL3729491 IC50 100.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3ccon3)csc12)Cc1ccccc1 CHEMBL3729472 IC50 100.0 nM
O=C(Nc1ccccc1)Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3727971 IC50 100.0 nM
c1cnc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)cn1 CHEMBL3730828 IC50 100.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)[C@@H]1CCCO1 CHEMBL3731282 IC50 100.0 nM
Fc1cnc(Nc2cnccn2)cc1-c1nc(N[C@@H]2CCNC2)c2sccc2n1 CHEMBL3732952 IC50 100.0 nM
C[C@@H](Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccccc1 CHEMBL3729791 IC50 100.0 nM
C[C@H](Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccccc1 CHEMBL3730334 IC50 100.0 nM
Cc1ccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)nn1 CHEMBL3731525 IC50 100.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1cccs1 CHEMBL3729940 IC50 100.0 nM
COc1cccc(C(=O)Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)c1 CHEMBL3731535 IC50 100.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)C1CC1 CHEMBL3729368 IC50 100.0 nM
c1ccc(-c2ccc(Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)nc2)cc1 CHEMBL3732659 IC50 100.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(Nc2ccc(N3CCOCC3)cn2)n1 CHEMBL3728881 IC50 100.0 nM
CN1CCN(c2ccc(Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)nc2)CC1 CHEMBL3732541 IC50 100.0 nM
N#Cc1ccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)nc1 CHEMBL3729348 IC50 100.0 nM
CN1CCN(c2cccc(Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)c2)CC1 CHEMBL3731806 IC50 100.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(Nc2ccc(N3CCCCC3)cc2)n1 CHEMBL3732947 IC50 100.0 nM
CN1CCN(C(=O)c2ccc(Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)cc2)CC1 CHEMBL3727913 IC50 100.0 nM
c1cn(Cc2ccc(Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)cc2)cn1 CHEMBL3730395 IC50 100.0 nM
c1csc(-c2ccc(Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)cc2)c1 CHEMBL3727390 IC50 100.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(Nc2ccc(-c3ccsc3)cc2)n1 CHEMBL3728090 IC50 100.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccc(F)cc1 CHEMBL3728196 IC50 100.0 nM
CN1CCN(c2ccc(C(=O)Nc3cc(-c4nc(N[C@@H]5CCNC5)c5sccc5n4)ccn3)cc2)CC1 CHEMBL3728075 IC50 100.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccc(N2CCOCC2)cc1 CHEMBL3728175 IC50 100.0 nM
COc1cc2c(cc1-c1cnn3ccc(-c4ccnc5[nH]ccc45)nc13)CNC2 CHEMBL4211722 IC50 110.0 nM
COc1cc(CN)ccc1-n1cnc2ccc(-c3ccnc4[nH]ccc34)cc21 CHEMBL4208982 IC50 120.0 nM
NC1CCCCC1Nc1nccc(-c2c[nH]c3ncccc23)n1 CHEMBL1995813 pKi 199.53 nM
CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21 CHEMBL494089 Kd 250.0 nM
Cc1n[nH]c2cnc(-c3cncc(OCC(N)Cc4cccc(C(F)(F)F)c4)c3)cc12 CHEMBL1998159 pKi 251.19 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 255.0 nM
Nc1ncc(-c2cccc(N3CCNCC3)c2)nc1C(=O)Nc1ccncc1 CHEMBL4517782 IC50 270.0 nM
c1cc(-c2ccc3ncn(-c4ccc5c(c4)CNC5)c3c2)c2cc[nH]c2n1 CHEMBL4215492 IC50 290.0 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 314.0 nM
Nc1ncc(-c2cccc(N3CCNCC3)c2)cc1C(=O)Nc1ccncc1 CHEMBL4471416 IC50 340.0 nM
OC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1991674 pKi 398.11 nM
CN1CCN(c2nc(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc3n2)CC1 CHEMBL565612 pKi 398.11 nM
NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL1998121 pKi 501.19 nM
COc1cc2c(cc1-c1cnc3ccc(-c4ccnc5[nH]ccc45)cn13)CNC2 CHEMBL4206023 IC50 570.0 nM
NCc1cccc(Cc2cnc(N)c(C(=O)Nc3ccncc3)c2)c1 CHEMBL4441139 IC50 710.0 nM
Cc1sc(C(=O)N[C@@H]2[C@H](N)CCCC2(F)F)cc1-c1cnn2cc(Cl)cnc12 CHEMBL4552628 IC50 720.0 nM
NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccc(Cl)cc1Cl CHEMBL1965660 pKi 794.33 nM
NCc1ccc(-n2cnc3ccc(-c4ccnc5[nH]ccc45)cc32)cc1 CHEMBL4205851 IC50 800.0 nM
CCOC(=O)c1c(-c2ccc(N(C)C)cc2)csc1N CHEMBL2393448 IC50 900.0 nM
COc1cccc(COC(=O)c2c(-c3ccc(OC)c(OC)c3)csc2N)c1 CHEMBL2393431 IC50 900.0 nM
CC1CCCN1CCc1cc2cc(-c3ccc(OC(F)(F)F)cc3)ccc2[nH]1 CHEMBL1990635 pKi 1000.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(Cl)c4)c3)cc12 CHEMBL1974870 pKi 1000.0 nM
Cn1c(NCC(N)Cc2ccccc2)nc(-c2ccncc2)c(-c2ccc3ccccc3c2)c1=O CHEMBL1990496 pKi 1000.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccc(Cl)c(Cl)c4)c3)cc12 CHEMBL1991063 pKi 1000.0 nM
O=C(NNC(=S)Nc1ccc(F)cc1)C(O)(c1ccccc1)c1ccccc1 CHEMBL1975138 pKi 1000.0 nM
Clc1cc(NC2CCCCC2)nc(-c2c[nH]c3ncccc23)n1 CHEMBL1997846 pKi 1000.0 nM
CC(C)(C)[Si](C)(C)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3731951 IC50 1000.0 nM
Cc1csc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)c1 CHEMBL3731749 IC50 1000.0 nM
CC(C)Cn1cc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)cn1 CHEMBL3730403 IC50 1000.0 nM
Cc1noc(C)c1-c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729655 IC50 1000.0 nM
Cn1nccc1-c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3728993 IC50 1000.0 nM
Cc1c(-c2ccn[nH]2)sc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3729908 IC50 1000.0 nM
CN(CCN)c1nc(-c2ccncc2)nc2c1sc1cccc(Cl)c12 CHEMBL3733020 IC50 1000.0 nM
Clc1cccc2sc3c(N[C@@H]4CCNC4)nc(-c4ccncc4)nc3c12 CHEMBL3731633 IC50 1000.0 nM
Cc1cc(C)c2c(n1)sc1c(NC[C@@H](C)N)nc(-c3ccncc3)nc12 CHEMBL3733109 IC50 1000.0 nM
Cc1cc(C)c2c(n1)sc1c(N3CCCNCC3)nc(-c3ccncc3)nc12 CHEMBL3728474 IC50 1000.0 nM
Cc1cc(C)c2c(n1)sc1c(N3CCNCC3)nc(-c3ccncc3)nc12 CHEMBL3729415 IC50 1000.0 nM
C[C@H](N)CNc1nc(-c2ccncc2)nc2c1sc1ncccc12 CHEMBL3729301 IC50 1000.0 nM
c1cnc2sc3c(N4CCCNCC4)nc(-c4ccncc4)nc3c2c1 CHEMBL3730226 IC50 1000.0 nM
NCCNc1nc(-c2ccncc2)nc2c1sc1ncccc12 CHEMBL3728384 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2ccsc12)Cc1ccccc1 CHEMBL3729811 IC50 1000.0 nM
Cc1csc2c(NC[C@@H](C)N)nc(-c3ccncc3)nc12 CHEMBL3731918 IC50 1000.0 nM
c1ccc(-c2cc3nc(-c4ccncc4)nc(N4CCCNCC4)c3s2)cc1 CHEMBL3730295 IC50 1000.0 nM
Cc1csc2c(N(C)CCN)nc(-c3ccncc3)nc12 CHEMBL3733358 IC50 1000.0 nM
Fc1cnccc1-c1nc(N[C@@H]2CCNC2)c2scc(Br)c2n1 CHEMBL3730731 IC50 1000.0 nM
CC(C)C[C@H](N)CNc1nc(-c2ccncc2)nc2c(Br)csc12 CHEMBL3727886 IC50 1000.0 nM
CNCCNc1nc(-c2ccncc2)nc2c(Br)csc12 CHEMBL3732845 IC50 1000.0 nM
Brc1csc2c(N[C@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3729098 IC50 1000.0 nM
Cc1csc2c(N[C@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3730767 IC50 1000.0 nM
CC(C)(C)c1sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1Br CHEMBL3728625 IC50 1000.0 nM
Cc1sc2c(N[C@H]3CCNC3)nc(-c3ccncc3)nc2c1Br CHEMBL3732559 IC50 1000.0 nM
Cc1sc2c(NC[C@@H](C)N)nc(-c3ccncc3)nc2c1Br CHEMBL3728254 IC50 1000.0 nM
Cc1sc2c(NC[C@H](C)N)nc(-c3ccncc3)nc2c1Br CHEMBL3729448 IC50 1000.0 nM
Cc1sc2c(NC[C@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1Br CHEMBL3729610 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2c(-c3ccc(Br)cc3)csc12)Cc1ccccc1 CHEMBL3731582 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3ccc(Br)cc3)csc12)Cc1ccccc1 CHEMBL3730108 IC50 1000.0 nM
Clc1cnccc1-c1nc(N[C@@H]2CCNC2)c2sccc2n1 CHEMBL3728734 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2Cl)nc2ccsc12)Cc1ccccc1 CHEMBL3731209 IC50 1000.0 nM
Cc1n[nH]c(C)c1-c1nc(NC[C@@H](N)Cc2ccccc2)c2c3c(sc2n1)CCCC3 CHEMBL3731302 IC50 1000.0 nM
COc1cccc(C[C@H](N)COc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)c1 CHEMBL3730597 IC50 1000.0 nM
COc1ccc(C[C@H](N)COc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)cc1 CHEMBL3729318 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccc2ccccc12 CHEMBL3728068 IC50 1000.0 nM
c1cc(-c2nc(OC[C@H]3CCCCN3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3727444 IC50 1000.0 nM
Cc1ccccc1C[C@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3729122 IC50 1000.0 nM
N[C@@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccc2ccccc12 CHEMBL3728861 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccc(Br)cc1 CHEMBL3728808 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccs1 CHEMBL3729786 IC50 1000.0 nM
Cc1ccc(C[C@H](N)COc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)cc1 CHEMBL3729288 IC50 1000.0 nM
Cc1cccc(C[C@H](N)COc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)c1 CHEMBL3733354 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccccc1F CHEMBL3728311 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccc(F)c1 CHEMBL3728689 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)CC1CCCCC1 CHEMBL3731304 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)C1CCCCC1 CHEMBL3728266 IC50 1000.0 nM
N[C@H](COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)c1ccccc1 CHEMBL3732352 IC50 1000.0 nM
c1cc(-c2nc(OC[C@@H]3CCCN3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3731452 IC50 1000.0 nM
c1cc(-c2nc(OC[C@H]3CCCN3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3728937 IC50 1000.0 nM
c1cc(-c2nc(OC3CNC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3729503 IC50 1000.0 nM
CC(C)[C@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3729554 IC50 1000.0 nM
CC[C@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3727756 IC50 1000.0 nM
CC[C@@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3731827 IC50 1000.0 nM
CC(C)C[C@@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3728670 IC50 1000.0 nM
C[C@@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3729930 IC50 1000.0 nM
c1cc(-c2nc(OC3CCCNC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3731222 IC50 1000.0 nM
c1cc(-c2nc(O[C@H]3CCNC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3729958 IC50 1000.0 nM
c1cc(-c2nc(O[C@@H]3CCNC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3729003 IC50 1000.0 nM
CC(C)C[C@H](N)COc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3732881 IC50 1000.0 nM
CNCCOc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3731649 IC50 1000.0 nM
CN(C)CCOc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3732709 IC50 1000.0 nM
CN1CCN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CC1 CHEMBL3729812 IC50 1000.0 nM
CCN1CCN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CC1 CHEMBL3729925 IC50 1000.0 nM
c1cc(CN2CCN(c3nc(-c4ccncc4)nc4sc5c(c34)CCCC5)CC2)ccn1 CHEMBL3728737 IC50 1000.0 nM
CC(=O)N1CCc2c(sc3nc(-c4ccncc4)nc(NCCN)c23)C1 CHEMBL3732553 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2O)nc2sc3c(c12)CCCC3)Cc1ccccc1 CHEMBL3729676 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2sc3c(c12)CCCC3)Cc1ccccc1 CHEMBL3732670 IC50 1000.0 nM
C[C@@H](N)CNc1nc(-c2ccncc2F)nc2sc3c(c12)CCCC3 CHEMBL3728676 IC50 1000.0 nM
C[C@H](N)CNc1nc(-c2ccncc2F)nc2sc3c(c12)CCCC3 CHEMBL3729311 IC50 1000.0 nM
NCCNc1nc(-c2ccncc2F)nc2sc3c(c12)CCCC3 CHEMBL3727537 IC50 1000.0 nM
Brc1ccc(-c2csc3nc(-c4ccncc4)nc(N4CCCNCC4)c23)cc1 CHEMBL3732696 IC50 1000.0 nM
Cc1sc2nc(-c3ccncc3)nc(N3CCCNCC3)c2c1-c1ccccc1 CHEMBL3728274 IC50 1000.0 nM
Cc1sc2nc(-c3ccncc3)nc(NCCN)c2c1-c1ccccc1 CHEMBL3732270 IC50 1000.0 nM
CC(C)(C)OC(=O)N1CCc2c(sc3nc(-c4ccncc4)nc(NC[C@@H](N)Cc4ccccc4)c23)C1 CHEMBL3732456 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCOC3)Cc1ccccc1 CHEMBL3728657 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCSC3)Cc1ccccc1 CHEMBL3732291 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCC1(C3)OCCO1)Cc1ccccc1 CHEMBL3730311 IC50 1000.0 nM
CC(C)c1cc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2s1 CHEMBL3729587 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCN(C(=O)c1ccccc1)C3)Cc1ccccc1 CHEMBL3732003 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCN(C(=O)c1ccccc1)C3)Cc1ccccc1 CHEMBL3731636 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccccc1 CHEMBL3730647 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3)Cc1ccccc1 CHEMBL3728703 IC50 1000.0 nM
CC[C@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3732827 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1c[nH]c2ccccc12 CHEMBL3732000 IC50 1000.0 nM
c1cc(-c2nc(NC[C@H]3CCCCN3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3732984 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1csc2ccccc12 CHEMBL3729541 IC50 1000.0 nM
CC(C)(C)C[C@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3732634 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccccn1 CHEMBL3729839 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccncc1 CHEMBL3729897 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccc(O)cc1 CHEMBL3731205 IC50 1000.0 nM
COc1cccc(C[C@H](N)CNc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)c1 CHEMBL3728314 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1cccc2ccccc12 CHEMBL3730187 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1ccc(F)cc1 CHEMBL3730055 IC50 1000.0 nM
COc1ccccc1C[C@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3728164 IC50 1000.0 nM
Cc1ccc(C[C@H](N)CNc2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)cc1 CHEMBL3730128 IC50 1000.0 nM
NCCNc1nc(-c2ccncc2)nc2sc3c(c12)CCSC3 CHEMBL3728535 IC50 1000.0 nM
CC1(C)CCc2c(sc3nc(-c4ccncc4)nc(NCCN)c23)C1 CHEMBL3732355 IC50 1000.0 nM
NCCNc1nc(-c2ccncc2)nc2sc3c(c12)CCC1(C3)OCCO1 CHEMBL3730147 IC50 1000.0 nM
CC(C)c1cc2c(NCCN)nc(-c3ccncc3)nc2s1 CHEMBL3731554 IC50 1000.0 nM
Cc1sc2nc(-c3ccncc3)nc(NC[C@@H](C)N)c2c1C CHEMBL3732937 IC50 1000.0 nM
Cc1sc2nc(-c3ccncc3)nc(NC[C@H](C)N)c2c1C CHEMBL3732811 IC50 1000.0 nM
CCc1cc2c(NC[C@@H](C)N)nc(-c3ccncc3)nc2s1 CHEMBL3727950 IC50 1000.0 nM
CCc1cc2c(NC[C@H](C)N)nc(-c3ccncc3)nc2s1 CHEMBL3731939 IC50 1000.0 nM
CCc1cc2c(NCCN)nc(-c3ccncc3)nc2s1 CHEMBL3731799 IC50 1000.0 nM
CCc1c(C)sc2nc(-c3ccncc3)nc(NC[C@H](C)N)c12 CHEMBL3730909 IC50 1000.0 nM
CC(C)Cc1csc2nc(-c3ccncc3)nc(NC[C@@H](C)N)c12 CHEMBL3730639 IC50 1000.0 nM
C[C@@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCCC3 CHEMBL3732957 IC50 1000.0 nM
C[C@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCCC3 CHEMBL3732747 IC50 1000.0 nM
CC1CCc2c(sc3nc(-c4ccncc4)nc(NC[C@@H](C)N)c23)C1 CHEMBL3733048 IC50 1000.0 nM
CC1CCc2c(sc3nc(-c4ccncc4)nc(NC[C@H](C)N)c23)C1 CHEMBL3731522 IC50 1000.0 nM
c1cc(-c2nc(N[C@H]3CCNC3)c3c4c(sc3n2)CCCC4)ccn1 CHEMBL3732226 IC50 1000.0 nM
CC[C@@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3730853 IC50 1000.0 nM
CC(C)C[C@@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3727406 IC50 1000.0 nM
C[C@@H]1CN[C@@H](C)CN1c1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3732791 IC50 1000.0 nM
C[C@@H]1CN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)C[C@H](C)N1 CHEMBL3732255 IC50 1000.0 nM
N[C@@H](CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3)Cc1c[nH]c2ccccc12 CHEMBL3728732 IC50 1000.0 nM
CSCC[C@@H](N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3727609 IC50 1000.0 nM
CN(C)CCNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 CHEMBL3730443 IC50 1000.0 nM
O[C@H]1CNC[C@@H]1Nc1nc(-c2ccncc2)nc2ccsc12 CHEMBL3729212 IC50 1000.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3728330 IC50 1000.0 nM
c1cc(-c2nc(N[C@@H]3CCCNC3)c3sccc3n2)ccn1 CHEMBL3729550 IC50 1000.0 nM
Cc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3732235 IC50 1000.0 nM
NCCNc1nc(-c2ccncc2)nc2c(-c3ccc(Br)cc3)csc12 CHEMBL3729853 IC50 1000.0 nM
Cc1sc2c(NCCN)nc(-c3ccncc3)nc2c1C CHEMBL3727448 IC50 1000.0 nM
c1ccc(-c2cc3nc(-c4ccncc4)nc(N4CCNCC4)c3s2)cc1 CHEMBL3730046 IC50 1000.0 nM
c1ccc(C[C@H]2CN(c3nc(-c4cn[nH]c4)nc4sc5c(c34)CCCC5)CCN2)cc1 CHEMBL3731140 IC50 1000.0 nM
Cc1n[nH]c(C)c1-c1nc(NC[C@H](C)N)c2c3c(sc2n1)CCCC3 CHEMBL3732178 IC50 1000.0 nM
C[C@@H](N)CNc1nc(-c2cn[nH]c2)nc2sc3c(c12)CCCC3 CHEMBL3731690 IC50 1000.0 nM
CC(C)(C)/C=C/c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729728 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(-c3cccnc3)csc12)Cc1ccccc1 CHEMBL3731261 IC50 1000.0 nM
Cn1cc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)cn1 CHEMBL3732491 IC50 1000.0 nM
Cc1ccc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)o1 CHEMBL3729295 IC50 1000.0 nM
Cn1ccc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)n1 CHEMBL3731857 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3cc(C(F)(F)F)[nH]n3)csc12)Cc1ccccc1 CHEMBL3731249 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3cncnc3)csc12)Cc1ccccc1 CHEMBL3727961 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3cccnc3)csc12)Cc1ccccc1 CHEMBL3727880 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccc(CO)cc3)csc12)Cc1ccccc1 CHEMBL3728424 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3cccc(CO)c3)csc12)Cc1ccccc1 CHEMBL3730885 IC50 1000.0 nM
NCc1ccc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4F)nc23)cc1 CHEMBL3729173 IC50 1000.0 nM
Cc1noc(C)c1-c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3F)nc12 CHEMBL3732246 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccncc3)csc12)Cc1ccccc1 CHEMBL3728500 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccc(F)cc3)csc12)Cc1ccccc1 CHEMBL3730943 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccsc3)csc12)Cc1ccccc1 CHEMBL3731215 IC50 1000.0 nM
Cc1ccccc1-c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3F)nc12 CHEMBL3731044 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(-c3ccccc3)csc12)Cc1ccccc1 CHEMBL3727828 IC50 1000.0 nM
NCc1coc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4F)nc23)c1 CHEMBL3727425 IC50 1000.0 nM
CC(C)(C)c1sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1-c1cn[nH]c1 CHEMBL3727748 IC50 1000.0 nM
Cc1sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1-c1ccc(F)nc1 CHEMBL3731292 IC50 1000.0 nM
Cc1ccc(-c2c(C(C)(C)C)sc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)s1 CHEMBL3731347 IC50 1000.0 nM
CNc1ccc(-c2c(C(C)(C)C)sc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)cc1 CHEMBL3729747 IC50 1000.0 nM
Cc1sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1-c1ccccc1 CHEMBL3733276 IC50 1000.0 nM
CC(C)(C)c1sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc2c1-c1ccn[nH]1 CHEMBL3732623 IC50 1000.0 nM
Clc1cccc2sc3c(OC[C@@H]4CCCN4)nc(-c4ccncc4)nc3c12 CHEMBL3729309 IC50 1000.0 nM
Cc1csc2c(O[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3732047 IC50 1000.0 nM
c1ccc(Nc2csc3c(N[C@@H]4CCNC4)nc(-c4ccncc4)nc23)nc1 CHEMBL3731054 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(Nc3ccncn3)csc12)Cc1ccccc1 CHEMBL3732053 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2F)nc2c(Nc3ccccc3)csc12)Cc1ccccc1 CHEMBL3731757 IC50 1000.0 nM
Cc1ccccc1Nc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3F)nc12 CHEMBL3728087 IC50 1000.0 nM
Fc1cccc(Nc2csc3c(N[C@@H]4CCNC4)nc(-c4ccncc4F)nc23)c1 CHEMBL3730120 IC50 1000.0 nM
Cc1c(C#CC(C)(C)O)sc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3729030 IC50 1000.0 nM
CC(C)(O)C#Cc1c(C(C)(C)C)sc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3733344 IC50 1000.0 nM
CC(C)(C)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3730938 IC50 1000.0 nM
CC(C)(N)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729896 IC50 1000.0 nM
CC(C)(O)C#Cc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3F)nc12 CHEMBL3728683 IC50 1000.0 nM
CCC[C@@H](O)[C@H](O)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3732290 IC50 1000.0 nM
CC(C)[C@](C)(O)C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3727773 IC50 1000.0 nM
CCC(O)(C#Cc1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12)CC CHEMBL3730568 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(C#CCCCO)csc12)Cc1ccccc1 CHEMBL3727903 IC50 1000.0 nM
C#Cc1sc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc2c1C CHEMBL3730528 IC50 1000.0 nM
CN(C)C(=O)c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3727409 IC50 1000.0 nM
CCN(CC)C(=O)c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3730401 IC50 1000.0 nM
CC(C)NC(=O)c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3729783 IC50 1000.0 nM
CC(C)(C)NC(=O)c1csc2c(NC[C@@H](N)Cc3ccccc3)nc(-c3ccncc3)nc12 CHEMBL3728817 IC50 1000.0 nM
N[C@H](CNc1nc(-c2ccncc2)nc2c(CCC3CC3)csc12)Cc1ccccc1 CHEMBL3732703 IC50 1000.0 nM
N[C@H](CNc1nc(-c2cc[n+]([O-])cc2)nc2c(Br)csc12)Cc1ccccc1 CHEMBL3732298 IC50 1000.0 nM
N[C@H](CNc1nc(-c2cc[n+]([O-])cc2)nc2c(-c3ccn[nH]3)csc12)Cc1ccccc1 CHEMBL3727554 IC50 1000.0 nM
Nc1csc2c(N[C@@H]3CCNC3)nc(-c3ccncc3)nc12 CHEMBL3729586 IC50 1000.0 nM
CCc1cc(-c2csc3c(NC[C@@H](N)Cc4ccccc4)nc(-c4ccncc4)nc23)no1 CHEMBL3728943 IC50 1000.0 nM
c1ccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)cc1 CHEMBL3732834 IC50 1000.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccco1 CHEMBL3731611 IC50 1000.0 nM
Fc1cnc(Nc2ccccc2)cc1-c1nc(N[C@@H]2CCNC2)c2sccc2n1 CHEMBL3730364 IC50 1000.0 nM
CN(C)C(=O)Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3729107 IC50 1000.0 nM
CC(C)(C)NC(=O)Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3728322 IC50 1000.0 nM
CNC(=O)Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3730634 IC50 1000.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)N1CCCCC1 CHEMBL3732723 IC50 1000.0 nM
Fc1c(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccnc1Nc1cnccn1 CHEMBL3728398 IC50 1000.0 nM
CC[C@H](Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccccc1 CHEMBL3728040 IC50 1000.0 nM
CC[C@@H](Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccccc1 CHEMBL3730659 IC50 1000.0 nM
C[C@H](O)CNc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3732375 IC50 1000.0 nM
C[C@@H](O)CNc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3731352 IC50 1000.0 nM
O[C@@H](CNc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1ccccc1 CHEMBL3730161 IC50 1000.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(NC2CC2)n1 CHEMBL3732862 IC50 1000.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(NCC2CC2)n1 CHEMBL3731860 IC50 1000.0 nM
c1ccc(CNc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)cc1 CHEMBL3730316 IC50 1000.0 nM
c1ccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)nc1 CHEMBL3729119 IC50 1000.0 nM
N#Cc1cccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)c1 CHEMBL3731598 IC50 1000.0 nM
N#Cc1ccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)cc1 CHEMBL3733111 IC50 1000.0 nM
CN(C)S(=O)(=O)c1ccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)cc1 CHEMBL3730825 IC50 1000.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(Nc2ccc(CN3CCCC3)cc2)n1 CHEMBL3727431 IC50 1000.0 nM
CC(C)S(=O)(=O)c1cccc(Nc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)c1 CHEMBL3729210 IC50 1000.0 nM
O=C(Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1)c1cnccn1 CHEMBL3729742 IC50 1000.0 nM
CC(C)Nc1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)ccn1 CHEMBL3730064 IC50 1000.0 nM
O=C(Nc1cc(-c2nc(N[C@H]3CNC[C@@H]3O)c3sccc3n2)ccn1)c1cccs1 CHEMBL3730182 IC50 1000.0 nM
CN1CC[C@@H](Nc2nc(-c3ccnc(NC(=O)c4cccs4)c3)nc3ccsc23)C1 CHEMBL3733148 IC50 1000.0 nM
NC(=O)CN1C[C@H](Nc2nc(-c3ccnc(NC(=O)c4cccs4)c3)nc3ccsc23)[C@@H](O)C1 CHEMBL3729346 IC50 1000.0 nM
c1cc(-c2nc(N[C@@H]3CCNC3)c3sccc3n2)cc(Sc2cc(-c3nc(N[C@@H]4CCNC4)c4sccc4n3)ccn2)n1 CHEMBL3731080 IC50 1000.0 nM
Cc1[nH]ncc1-c1nc(NC[C@@H](N)Cc2ccccc2)c2sccc2n1 CHEMBL3730583 IC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM