Cc1cc2ncnn2cc1Nc1ncc2c(n1)n([C@H]1CC[C@H](O)CC1)c(=O)n2C CHEMBL4447991 pIC50 0.07943 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C CHEMBL5180090 IC50 0.12 nM
Cc1cc2nccnc2cc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C CHEMBL5194436 IC50 0.13 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(C1CCCCC1)c(=O)n2C CHEMBL4560221 pIC50 0.1585 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(C1CCC(F)(F)CC1)c(=O)n2C CHEMBL4450232 pIC50 0.1995 nM
Cc1cc2nccn2cc1Nc1ncc2c(n1)n([C@H]1CC[C@H](O)CC1)c(=O)n2C CHEMBL4553941 pIC50 0.2512 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccccc1C#N CHEMBL3646708 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(F)(F)c1ccccc1 CHEMBL3646711 IC50 0.3 nM
COC(=O)C(Oc1cc2c(cc1OC)ncc1c2c(-c2ccc(C#N)cc2)nn1C)c1ccc(F)cc1 CHEMBL3646712 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OS(=O)(=O)c1ccc(C)cc1 CHEMBL3646718 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OP(=O)(O)c1ccccc1 CHEMBL3646719 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccc(CN2CCOCC2)c1 CHEMBL3646722 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cnc2[nH]ccc2c1 CHEMBL3646724 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccc(CN)c1 CHEMBL3646726 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccnc(C#N)c1 CHEMBL3646732 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccc(N(C)C)c1 CHEMBL3646735 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccc(-c2csc(C)n2)c1 CHEMBL3639456 IC50 0.3 nM
CCN1CCN(CCNC(=O)C(Oc2cc3c(cc2OC)ncc2c3c(-c3ccc(C#N)cc3)nn2C)c2ccc(F)cc2)CC1 CHEMBL3646741 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(=O)NCCN(C)C)c1ccc(F)cc1 CHEMBL3646742 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(=O)NOCC#N)c1ccc(F)cc1 CHEMBL3646744 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(=O)NCCS(N)(=O)=O)c1ccc(F)cc1 CHEMBL3646745 IC50 0.3 nM
CCn1nc(-c2ccc(C#N)cc2F)c2c3cc(OC)c(OC)cc3ncc21 CHEMBL3646750 IC50 0.3 nM
CCCn1nc(-c2ccc(C#N)cc2)c2c3cc(OC)c(OC)cc3ncc21 CHEMBL3646752 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C(C)C)c2cc1OC CHEMBL3646753 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C3CC3)c2cc1OC CHEMBL3646755 IC50 0.3 nM
C=CCn1nc(-c2ccc(C#N)cc2)c2c3cc(OC)c(OC)cc3ncc21 CHEMBL3646756 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C#N)c2cc1OC CHEMBL3646758 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3CC(=O)O)c2cc1OC CHEMBL3646760 IC50 0.3 nM
COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3CC(N)=O)c2cc1OC CHEMBL3646761 IC50 0.3 nM
CCN1CCN(c2ccc(-c3nn(C)c4cnc5cc(OC)c(OC)cc5c34)cc2)CC1 CHEMBL3646768 IC50 0.3 nM
COCCNC(=O)C(Oc1cc2c(cc1OC)ncc1c2n(-c2ccc(C#N)cc2F)c(=O)n1C)c1ccc(F)cc1 CHEMBL3667683 IC50 0.3 nM
COc1cc2ncc3c(c2cc1OCc1sccc1S(=O)(=O)N1CCOCC1)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3667686 IC50 0.3 nM
COc1cc2ncc3c(c2cc1OC(CN)c1cccs1)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3672673 IC50 0.3 nM
COc1cc2ncc3c(c2cc1-c1ccnn1C)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3672679 IC50 0.3 nM
COc1cc2ncc3c(c2cc1-c1cc(C(F)(F)F)nn1C)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3672681 IC50 0.3 nM
COc1cc2ncc3c(c2cc1CCc1ccsc1)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3672683 IC50 0.3 nM
COc1cc2ncc3c(c2cc1/C=C/c1ccccc1)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3672684 IC50 0.3 nM
COc1ccc(Nc2ncc3c(n2)n([C@H]2CC[C@H](O)CC2)c(=O)n3C)c(C)c1 CHEMBL4555040 pIC50 0.3162 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n([C@H]1CC[C@](C)(O)CC1)c(=O)n2C CHEMBL4581254 pIC50 0.3162 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@H]1CCN(C3COC3)C1)c(=O)n2C CHEMBL5197250 IC50 0.37 nM
Cc1cc2nccn2cc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C CHEMBL4474647 pIC50 0.3981 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n([C@H]1CC[C@@](C)(O)CC1)c(=O)n2C CHEMBL4513701 pIC50 0.3981 nM
CC(C)n1nc(-c2ccc3nc[nH]c(=O)c3c2)c2c(N)ncnc21 CHEMBL1241776 IC50 0.5 nM
Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL1765602 IC50 0.5 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@@H]1CNC[C@H]1F)c(=O)n2C CHEMBL5170489 IC50 0.51 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C CHEMBL4439259 IC50 0.6 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@@H]1CN(C)C[C@H]1F)c(=O)n2C CHEMBL5179972 IC50 0.64 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cccc12 CHEMBL188678 Ki 0.65 nM
Cc1cc2nccnc2cc1Nc1ncc2c(n1)n(C1CCN(C)CC1)c(=O)n2C CHEMBL5196848 IC50 0.69 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n(C1CCNCC1)c(=O)n2C CHEMBL5192430 IC50 0.69 nM
COc1cc2ncc3c(c2cc1OC(CN)c1ccc(F)cc1)n(-c1ccc(C#N)cc1F)c(=O)n3C CHEMBL3672674 IC50 0.75 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@H]1CCN(CCO)C1)c(=O)n2C CHEMBL5191577 IC50 0.75 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)N(C1CCOCC1)CC(=O)N2C CHEMBL5191459 IC50 0.8 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)C1(CCC(C)(C)CC1)C(=O)N2C CHEMBL5178683 IC50 1.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(N1CC3CCC(C1)O3)c(=O)n2C CHEMBL5183684 IC50 1.0 nM
CCc1ncc(S(=O)(=O)Nc2cc(-c3ccc4ncc5c(c4c3)C3(CCC3)C(=O)N5C)cnc2OCCCN(C)C)s1 CHEMBL5175568 IC50 1.0 nM
CN(C)CCCOc1ncc(-c2ccc3ncc4c(c3c2)C2(CCC2)C(=O)N4C)cc1NS(=O)(=O)C(F)(F)F CHEMBL5205796 IC50 1.0 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@H]1CCN(C)C1)c(=O)n2C CHEMBL5198414 IC50 1.4 nM
COCCN1CC[C@H](n2c(=O)n(C)c3cnc(Nc4cc5cccnc5cc4C)nc32)C1 CHEMBL5204870 IC50 1.7 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@@H]1CNC[C@@H]1F)c(=O)n2C CHEMBL5178837 IC50 1.7 nM
COc1ccc(Nc2ncc3[nH]c(=O)n([C@H]4CC[C@H](O)CC4)c3n2)c(C)c1 CHEMBL4459057 pIC50 1.995 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccc(OCCNc4cccnc4)c4c3sc3ccccc34)cccc12 CHEMBL2420289 IC50 2.0 nM
COC(=O)[C@H](CO)NCCOc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420254 IC50 2.0 nM
CC(=O)N1CCN(CCOc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420287 IC50 2.0 nM
Oc1cccc(-c2nc(N3CCOCC3)c3oc4ncccc4c3n2)c1 CHEMBL573339 IC50 2.0 nM
Oc1cccc(-c2cc3c(oc4ncccc43)c(N3CCOCC3)n2)c1 CHEMBL3913354 IC50 2.0 nM
Cc1ccc2c(=O)nc(N3CCOCC3)oc2c1-c1cccc2c1sc1ccccc12 CHEMBL4073785 IC50 2.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(N1CCOCC1)c(=O)n2C CHEMBL5197528 IC50 2.0 nM
Cn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21 CHEMBL1879463 IC50 2.0 nM
O=S(=O)(Nc1cc(-c2ccc3nccc(N4CCOCC4)c3c2)cnc1Cl)c1ccc(F)cc1 CHEMBL1738719 IC50 2.3 nM
COc1ccc(Nc2ncc3c(n2)n(C2CCCCC2)c(=O)n3C)c(C)c1 CHEMBL4438672 pIC50 2.512 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@@H]1CCN(C)C1)c(=O)n2C CHEMBL5182028 IC50 2.6 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n([C@@H]1CN(C)C[C@@H]1F)c(=O)n2C CHEMBL5182752 IC50 2.7 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)n(C1CCN(C)CC1)c(=O)n2C CHEMBL5186637 IC50 2.9 nM
CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3)cc2s1 CHEMBL1615189 IC50 3.0 nM
CC(C)N1CCN(CCOc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420253 IC50 3.0 nM
CN(CCOc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12)CC(N)=O CHEMBL2420255 IC50 3.0 nM
Nc1nc2cc(-c3nn(CC4CCCC4)c4ncnc(N)c34)ccc2o1 CHEMBL3797933 IC50 3.0 nM
COc1ccc(C)c(Nc2ncc3c(n2)n([C@H]2CC[C@H](O)CC2)c(=O)n3C)c1 CHEMBL4474502 pIC50 3.162 nM
Cc1cc2nccnc2cc1Nc1ncc2c(n1)N(C1CCOCC1)CC(=O)N2C CHEMBL5175473 IC50 3.26 nM
CCN1C(=O)CN(C2CCOCC2)c2nc(Nc3cn4ncnc4cc3C)ncc21 CHEMBL5191714 IC50 3.37 nM
O=S(=O)(Nc1cc(-c2ccc3ncc(N4CCOCC4)nc3c2)cnc1Cl)c1ccc(F)cc1 CHEMBL1914743 IC50 3.4 nM
C[C@@H]1CN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)C[C@H](C)O1 CHEMBL2420439 IC50 4.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)C1(CCC3(CC3)CC1)C(=O)N2C CHEMBL5184207 IC50 4.0 nM
CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL1086377 IC50 5.0 nM
CC(=O)N1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420444 IC50 5.0 nM
CN(C)CCN(C)CCOc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420285 IC50 5.0 nM
O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420310 IC50 5.0 nM
Cc1ccc2c(=O)cc(N3CCOCC3)oc2c1-c1cccc2c1sc1ccccc12 CHEMBL3393500 IC50 5.0 nM
C[C@@H](Nc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12)c1ccc(Cl)cc1 CHEMBL4565988 IC50 5.0 nM
Cn1nc(C2CCOCC2)c2c3cc(-c4cncc(C(F)F)c4)ccc3ncc21 CHEMBL4870563 IC50 5.0 nM
COc1ccc(Nc2ncc3c(n2)n(C2CCCC2)c(=O)n3C)c(C)c1 CHEMBL4483014 pIC50 5.012 nM
Cc1c(Nc2ncc3c(n2)n([C@H]2CC[C@H](O)CC2)c(=O)n3C)ccc2nccn12 CHEMBL4529390 pIC50 5.012 nM
CNC(=O)c1ccc2c(c1)OCCc1cc(C(=O)N(C)c3ccc(C(=O)N(C)C)cc3Cl)sc1-2 CHEMBL1796761 IC50 6.0 nM
CC(CN(C)C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766797 Ki 6.0 nM
COC(=O)[C@H](CO)NC(=O)COc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420264 IC50 6.0 nM
O=C(CN1CCN(CCOCCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420446 IC50 6.0 nM
O=C(CN(CCO)CCO)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420426 IC50 6.0 nM
O=C(CCNCCN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420295 IC50 6.0 nM
O=C(CCNCCN1CCNC1=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420301 IC50 6.0 nM
CC(C)NCC(=O)CN1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420307 IC50 6.0 nM
COCCN1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420445 IC50 6.0 nM
Cn1c(=O)n([C@H]2CC[C@H](O)CC2)c2nc(Nc3ccc4ncnn4c3)ncc21 CHEMBL4586576 pIC50 6.31 nM
CCC(=O)N1CCN(c2ccc(-n3c(=O)ccc4cnc5ccc(-c6cnc7ccccc7c6)cc5c43)cc2C(F)(F)F)CC1 CHEMBL1256459 IC50 6.34 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)N(C1CCOCC1)CC(=O)N2C1CC1 CHEMBL5175439 IC50 6.76 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)N(C1CCOCC1)CC(=O)N2C CHEMBL5173245 IC50 6.9 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccc(OCCNCCN4CCOCC4)c4c3sc3ccccc34)cccc12 CHEMBL2420284 IC50 7.0 nM
O=C(CN1CCN(c2ccccn2)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420305 IC50 7.0 nM
COCCNCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420443 IC50 7.0 nM
O=C(CNCCN1CCNC1=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420441 IC50 7.0 nM
CN1CCN(CCOc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420281 IC50 7.0 nM
O=C(CCNCC1CCCO1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420296 IC50 7.0 nM
C[C@@H]1CN(c2cc(N3C[C@@H]4C[C@@H]4[C@@H]3Cc3ccccc3)[nH]c(=O)c2)CCO1 CHEMBL4856420 Ki 7.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)N(C1CCOCC1)CC(=O)N2 CHEMBL5193606 IC50 7.06 nM
Cn1c(=O)n([C@H]2CC[C@H](O)CC2)c2nc(Nc3ccc4nccn4c3)ncc21 CHEMBL4552812 pIC50 7.943 nM
CC(C)n1nc(-c2ccc3ncccc3c2)c2c(N)ncnc21 CHEMBL1233882 IC50 8.0 nM
O=C(CN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)cc1OCC1CC1 CHEMBL1669154 IC50 8.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccc(OCCN4CCOCC4)c4c3sc3ccccc34)cccc12 CHEMBL2420279 IC50 8.0 nM
CCN(CC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12)Cc1ccncc1 CHEMBL2420440 IC50 8.0 nM
O=C(CNCCO)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420428 IC50 8.0 nM
CN(C)CCOc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420288 IC50 8.0 nM
COCCNCCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420303 IC50 8.0 nM
NCCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420294 IC50 8.0 nM
O=C(CNCc1ccncc1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420314 IC50 8.0 nM
CC(C)n1nc(-c2ccc(C#N)c(O)c2)c2c(N)ncnc21 CHEMBL1241944 IC50 9.0 nM
C[C@@H]1CN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)C[C@H](C)O1 CHEMBL2420299 IC50 9.0 nM
CC(C)N1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420315 IC50 9.0 nM
O=C(CCNCCCN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420276 IC50 9.0 nM
COc1ccc(CNCCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)cc1 CHEMBL2420292 IC50 9.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccc4c(c3)OCCO4)csc12 CHEMBL2322228 IC50 9.0 nM
CC(C)n1nc(-c2ccc3c(N)n[nH]c3c2)c2c(N)ncnc21 CHEMBL1242476 IC50 10.0 nM
CN(C)CCN1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420272 IC50 10.0 nM
C[C@@H]1CN(CCOc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)C[C@H](C)O1 CHEMBL2420286 IC50 10.0 nM
O=C(COc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12)NCc1ccncc1 CHEMBL2420262 IC50 10.0 nM
O=C(CCNCCO)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420321 IC50 10.0 nM
CN(C)CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420308 IC50 10.0 nM
CN1CCCN(CCOc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420282 IC50 10.0 nM
Cc1ccccc1Nc1ncc2c(n1)n([C@H]1CC[C@H](O)CC1)c(=O)n2C CHEMBL4449235 pIC50 10.0 nM
COc1ccc(Nc2ncc3c(n2)n([C@H]2CC[C@H](O)CC2)c(=O)n3C)cc1 CHEMBL4466619 pIC50 10.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc(C5=CCCCC5)n4c3c2)c1 CHEMBL4875626 IC50 10.0 nM
Cc1cc2ncccc2cc1Nc1ncc2c(n1)C1(CCOCC1)C(=O)N2C CHEMBL5202679 IC50 10.47 nM
O=C(CCN1CCCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420291 IC50 11.0 nM
CN(CC(N)=O)C(=O)COc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420265 IC50 11.0 nM
O=C(CN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420323 IC50 11.0 nM
FC(F)c1cncc(-c2ccc3ncc4[nH]nc(C5CCOCC5)c4c3c2)c1 CHEMBL4869632 IC50 11.0 nM
Cn1nc(-c2ccc(Br)c(O)c2)c2c(N)ncnc21 CHEMBL1241299 IC50 12.0 nM
O=C(CNCCN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420435 IC50 12.0 nM
NCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420434 IC50 12.0 nM
CCN(CC)CCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420293 IC50 12.0 nM
O=C(CCNCc1ccncc1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420277 IC50 12.0 nM
CN1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420425 IC50 12.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc(C5=CCCCCC5)n4c3c2)c1 CHEMBL4860779 IC50 12.0 nM
COc1ccc(Nc2ncc3c(n2)n(-c2ccccc2)c(=O)n3C)c(C)c1 CHEMBL4450430 pIC50 12.59 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2C1CCCC1 CHEMBL1241676 IC50 13.0 nM
CN1CCCC1CCNCCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420302 IC50 13.0 nM
O=C(CNCCCN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420311 IC50 13.0 nM
COc1ccc2c(c1OC)N=C(NC(=O)c1cccnc1)N1CCN=C21 CHEMBL1241857 IC50 13.0 nM
O=c1cc(N2CCOCC2)nc2c(-c3cccc4c3sc3ccccc34)cccn12 CHEMBL3393499 IC50 13.0 nM
CCN1C(=O)CNc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21 CHEMBL3586573 IC50 13.0 nM
CC(C)n1nc(-c2ccc3nc(N)ccc3c2)c2c(N)ncnc21 CHEMBL1241949 IC50 14.0 nM
O=C(CN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)cc1-c1ccccc1 CHEMBL1669170 IC50 14.0 nM
O=C(CNCC1CCCO1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420436 IC50 14.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)n(C1CCN(C)CC1)c(=O)n2C CHEMBL5171684 IC50 14.0 nM
O=C(CN1CCN(c2ccc(F)cc2)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420306 IC50 15.0 nM
Cc1cc2nnccc2cc1Nc1ncc2c(n1)n(C1CCN(C)CC1)c(=O)n2C CHEMBL5198162 IC50 15.0 nM
NCCNCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420429 IC50 16.0 nM
CC(=O)N1CCN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420261 IC50 16.0 nM
CC(C)N1CCN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420263 IC50 16.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)C1(CCC(OCC(F)F)CC1)C(=O)N2C CHEMBL5169542 IC50 16.85 nM
CC(C)n1nc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21 CHEMBL1241484 IC50 17.0 nM
CC(C)n1nc(-c2ccc(Br)c(O)c2)c2c(N)ncnc21 CHEMBL1241578 IC50 17.0 nM
Cc1nc(C2CCOCC2)n2c1cnc1ccc(-c3cncc(C(F)F)c3)cc12 CHEMBL4852502 IC50 17.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4cccs4)c3)cccc12 CHEMBL529223 IC50 18.0 nM
CN(C)CC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420313 IC50 18.0 nM
O=C(CCN1CCN(c2ncccn2)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420271 IC50 18.0 nM
COCCN(CCOC)CC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420427 IC50 18.0 nM
Nc1ncnc2c1c(-c1ccc(Br)c(O)c1)nn2C1CCC1 CHEMBL1242287 IC50 19.0 nM
CC(C)n1nc(-c2ccc3c(C=O)c[nH]c3c2)c2c(N)ncnc21 CHEMBL1242666 IC50 19.0 nM
COCCN1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420266 IC50 19.0 nM
O=C(COc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12)N1CCCCC1 CHEMBL2420256 IC50 19.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)C2CCC(=O)[C@@]2(C)C[C@H]1C(=O)OC CHEMBL174207 IC50 20.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccsc4)c3)cccc12 CHEMBL488881 IC50 20.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccc(OCCN4CCCCC4)c4c3sc3ccccc34)cccc12 CHEMBL2420280 IC50 20.0 nM
O=c1c2ccccc2n(Cc2ccccc2)c2cc(N3CCOCC3)cc(O)c12 CHEMBL5423821 IC50 20.0 nM
O=C(CN1CCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420324 IC50 21.0 nM
Cc1cc2ncncc2cc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C CHEMBL5184141 IC50 21.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)C1(CCC1)C(=O)N2C CHEMBL5196879 IC50 21.45 nM
O=C(CN1CCCNCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420312 IC50 22.0 nM
CCN(CC)CCOc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420283 IC50 22.0 nM
NCCNCCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420322 IC50 22.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c5c(sc34)CCCC5)cccc12 CHEMBL198750 IC50 23.0 nM
CC(=O)N1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420304 IC50 23.0 nM
O=C(CCN1CCN(c2ccccn2)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420269 IC50 24.0 nM
O=C(CN1CCNCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420424 IC50 24.0 nM
Cc1cc2nnccc2cc1Nc1ncc2c(n1)n(C1CCOCC1)c(=O)n2C CHEMBL5181303 IC50 24.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)N(C1CCOCC1)CC(=O)N2C(C)C CHEMBL5186283 IC50 25.46 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766779 IC50 26.0 nM
O=C(CCN(CCO)CCO)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420320 IC50 26.0 nM
N#CCN1CCC(n2c(=O)cnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)CC1 CHEMBL4079746 IC50 26.0 nM
Cn1nc2cnc3ccc(-c4cncc(C(F)F)c4)cc3c2c1C1CCOCC1 CHEMBL4868400 IC50 26.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2[C@H]1CCOC1 CHEMBL1241678 IC50 28.0 nM
CN1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420319 IC50 28.0 nM
Cn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1234815 IC50 29.0 nM
O=C(CCN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420274 IC50 29.0 nM
O=C(CCN1CCN(CCOCCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420267 IC50 29.0 nM
CN1CCN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420257 IC50 29.0 nM
COc1ccc(C2(c3cc(-c4ncnc5cc(N6CCOCC6)ccc45)c(F)cc3Cl)CC2)nn1 CHEMBL5195439 IC50 29.0 nM
Nc1ncnc2c1c(-c1ccc(Br)c(O)c1)nn2C1CCCC1 CHEMBL1242376 IC50 30.0 nM
CCN1CCCC1CNCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420309 IC50 30.0 nM
O=C(CN1CCCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2417580 IC50 30.0 nM
O=C(CCN1CCN(c2ccc(F)cc2)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420270 IC50 30.0 nM
CCN(CCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12)Cc1ccncc1 CHEMBL2420300 IC50 31.0 nM
CO[C@H]1CC[C@H](c2nnc3cnc4ccc(-c5cncc(C(F)F)c5)cc4n32)CC1 CHEMBL4860129 IC50 32.0 nM
O=C(CCNCCN1CCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420297 IC50 33.0 nM
CCN1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420268 IC50 33.0 nM
O=c1cc(-c2ccccc2)oc2cc(N3CCOCC3)cc(O)c12 CHEMBL3288951 IC50 34.0 nM
O=c1nc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cccc12 CHEMBL3764883 IC50 34.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2[C@@H]1CCOC1 CHEMBL1241768 IC50 35.0 nM
O=C(c1ccc(O)cc1)c1ccc(N2CCOCC2)cc1O CHEMBL3393501 IC50 35.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc([C@H]5[C@@H]6COC[C@@H]65)n4c3c2)c1 CHEMBL4873263 IC50 35.0 nM
CC(C)n1nc(-c2ccc(O)c(F)c2)c2c(N)ncnc21 CHEMBL1241945 IC50 36.0 nM
Cn1nc(-c2ccc3ncccc3c2)c2c(N)ncnc21 CHEMBL1242756 IC50 36.0 nM
CC(C)(C#N)c1ccc(N2C(=O)OCc3cnc4ccc(-c5cnc6ccccc6c5)cc4c32)cc1 CHEMBL3334621 IC50 36.0 nM
O=C(CCN1CCNCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420318 IC50 37.0 nM
CC(C)N1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420278 IC50 37.0 nM
O=C(CCN1CCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420317 IC50 37.0 nM
COc1ccc(CNCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)cc1 CHEMBL2420432 IC50 38.0 nM
CO[C@H]1CC[C@@H](c2nnc3cnc4ccc(-c5cncc(C(F)F)c5)cc4n32)CC1 CHEMBL4850640 IC50 39.0 nM
Cc1ncc(-c2cc(NC[C@@H](C)c3cccc4c(-c5noc(=O)[nH]5)ccnc34)ncn2)cn1 CHEMBL5187533 IC50 39.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc4c3oc3ccccc34)cccc12 CHEMBL186048 IC50 40.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc([C@H]5[C@@H]6CCC[C@@H]65)n4c3c2)c1 CHEMBL4871998 IC50 40.0 nM
CN1CCCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420290 IC50 41.0 nM
O=C(CCN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420316 IC50 41.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc(C5=CCOCC5)n4c3c2)c1 CHEMBL4849035 IC50 41.0 nM
O=C(CCN1CCCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420275 IC50 42.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2C1CCC1 CHEMBL1241580 IC50 43.0 nM
CN1CCCC1CCNCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420442 IC50 43.0 nM
CN1CCCN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420258 IC50 44.0 nM
Nc1ncnc2c1c(-c1ccc3occc(=O)c3c1)nn2C1CCCC1 CHEMBL1242119 IC50 46.0 nM
COc1ccc(-c2nn(C3CCC3)c3ncnc(N)c23)cc1OC CHEMBL1233881 IC50 47.0 nM
Nc1ncnc2c1c(-c1ccc3ncccc3c1)nn2C1CCCC1 CHEMBL1241681 IC50 47.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)C(C)(C)C(=O)N2C CHEMBL5204430 IC50 47.95 nM
CC(C)n1nc(-c2cc(F)c(O)cc2F)c2c(N)ncnc21 CHEMBL1242028 IC50 48.0 nM
Nc1nc2cc(-c3nn(CC4CCCO4)c4ncnc(N)c34)ccc2o1 CHEMBL3797834 IC50 48.0 nM
Cc1nn(-c2ccccc2)nc1Cn1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242845 IC50 49.0 nM
CC(C)n1nc(-c2ccc3ccncc3c2)c2c(N)ncnc21 CHEMBL1242208 IC50 49.0 nM
CCN1CCCC1CNCCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420273 IC50 49.0 nM
O=C(CN1CCCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420431 IC50 51.0 nM
Nc1ncnc2c1c(-c1ccn3ccnc3c1)nn2C1CCCC1 CHEMBL1241675 IC50 53.0 nM
CN(C)CCN(C)C(=O)COc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420259 IC50 53.0 nM
Nc1ncnc2c1c(-c1ccc3cc[nH]c3c1)nn2C1CCCC1 CHEMBL1242664 IC50 54.0 nM
CN1CCCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 CHEMBL2420430 IC50 55.0 nM
CN(C)CCN(C)CC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420438 IC50 57.0 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1081312 IC50 60.0 nM
O=C(CNCCN1CCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420437 IC50 61.0 nM
C[C@@H]1CN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)C[C@H](C)O1 CHEMBL2420260 IC50 61.0 nM
C[C@@H](CN)n1nc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21 CHEMBL1240544 IC50 64.0 nM
CC(=O)/N=c1/[nH]c(C)c(-c2ccc(Cl)c(S(=O)(=O)NCCO)c2)s1 CHEMBL1229535 IC50 64.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc(C5=CCCOCC5)n4c3c2)c1 CHEMBL4851439 IC50 69.0 nM
CC(C)n1nc(-c2cnc3[nH]ccc3c2)c2c(N)ncnc21 CHEMBL1242293 IC50 71.0 nM
NS(=O)(=O)c1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4857669 IC50 74.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2[C@@H]1CCNC1 CHEMBL1241677 IC50 77.0 nM
CC(C)n1nc(-c2ccc3cn[nH]c3c2)c2c(N)ncnc21 CHEMBL1242477 IC50 77.0 nM
C[C@@H]1CN(CC(=O)Nc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL2140173 IC50 77.0 nM
CN(C)CCN(C)CCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420298 IC50 78.0 nM
CC(C)n1nc(-c2ccc3nc(Cl)ccc3c2)c2c(N)ncnc21 CHEMBL1241683 IC50 80.0 nM
Nc1ncnc2c1c(-c1ccc3[nH]ccc3c1)nn2C1CCCC1 CHEMBL1242295 IC50 80.0 nM
O=C(CN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)cc1O CHEMBL1669157 IC50 80.0 nM
C[C@H](CN1CCOCC1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4745255 IC50 82.0 nM
CCN(CC)CC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 CHEMBL2420433 IC50 84.0 nM
Nc1ncnc2c1c(-c1ccc3[nH]ncc3c1)nn2C1CCCC1 CHEMBL1242475 IC50 85.0 nM
Cn1nc(-c2cc3ccccc3s2)c2c(N)ncnc21 CHEMBL1240594 IC50 85.0 nM
CC(C)n1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242377 IC50 88.0 nM
CC(C)n1nc(-c2ccc3cc[nH]c3c2)c2c(N)ncnc21 CHEMBL1242574 IC50 88.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3cc(-c4ccsc4)cs3)cccc12 CHEMBL508479 IC50 90.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3cc(-c4ccccc4)cs3)cccc12 CHEMBL454422 IC50 90.0 nM
CC(C)n1nc(-c2ccc3[nH]ccc3c2)c2c(N)ncnc21 CHEMBL1242294 IC50 90.0 nM
O=c1nc(N2CCOCC2)oc2cc3ccc(OCc4ccccn4)cc3cc12 CHEMBL1795747 IC50 96.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(C#N)cc12 CHEMBL4593348 IC50 98.0 nM
CC(C)n1nc(-c2ccc3cc(O)ccc3c2)c2c(N)ncnc21 CHEMBL1242662 IC50 100.0 nM
CC(C)(c1nc(-c2ccc(F)c3[nH]ccc23)nc2c1OC[C@@H]1COCCN21)S(C)(=O)=O CHEMBL3918930 IC50 100.0 nM
Cc1ccc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2n1 CHEMBL1241682 IC50 102.0 nM
CC(C)n1nc(-c2ccc3[nH]ncc3c2)c2c(N)ncnc21 CHEMBL1242386 IC50 105.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4867528 IC50 105.0 nM
CC1CCC(n2nc(-c3ccc(F)c(O)c3)c3c(N)ncnc32)C1 CHEMBL1242656 IC50 107.0 nM
C[C@@H](Nc1c(C(N)=O)cnc2ccc(C#N)cc12)c1ccc(Cl)cc1 CHEMBL4527822 IC50 109.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCCC1 CHEMBL1242568 IC50 110.0 nM
Nc1ncnc2c1c(-c1ccc3cn[nH]c3c1)nn2C1CCCC1 CHEMBL1242572 IC50 110.0 nM
CC1(COc2cc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)ccc2NC(=O)CN2CCOCC2)CCC1 CHEMBL1669167 IC50 110.0 nM
C[C@@H]1CCN(c2nc(N3CCOCC3)cc(=O)[nH]2)[C@H]1Cc1ccccc1 CHEMBL4852400 Ki 110.0 nM
COc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1O CHEMBL1242201 IC50 111.0 nM
COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O CHEMBL428496 Ki 120.0 nM
Cn1nc(-c2cnc3[nH]ccc3c2)c2c(N)ncnc21 CHEMBL1240565 IC50 120.0 nM
CC(=O)c1ccc(N2CCOCC2)cc1O CHEMBL1317546 IC50 120.0 nM
Cc1cc(C(C)Nc2ccccc2)c2oc(N3CCOCC3)cc(=O)c2c1 CHEMBL2064328 IC50 120.0 nM
Cc1ncc(-c2cc(NC[C@H](C)c3cccc4c(C5=NCCN5)ccnc34)ncn2)cn1 CHEMBL5174476 IC50 122.0 nM
CS(=O)(=O)c1cncc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4851045 IC50 123.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCCN(C)C)nc4)cc3c21 CHEMBL5435260 IC50 123.0 nM
NS(=O)(=O)c1cncc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4863567 IC50 124.0 nM
Cn1c(=O)n([C@H]2CC[C@H](O)CC2)c2nc(Nc3ccccc3)ncc21 CHEMBL4456514 pIC50 125.89 nM
CC(C)n1nc(-c2ccc3nccnc3c2)c2c(N)ncnc21 CHEMBL1241774 IC50 126.0 nM
[2H]C([2H])([2H])N1C(=O)C2(CCOCC2)c2nc(Nc3cn4ncnc4cc3C)ncc21 CHEMBL5184834 IC50 126.5 nM
CCc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Nc4ccccc4)cc32)c(CC)c1CCC(=O)O CHEMBL2181108 IC50 130.0 nM
CCN1C(=O)C2(CCOCC2)c2nc(Nc3cn4ncnc4cc3C)ncc21 CHEMBL5187570 IC50 134.95 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccc(O)cc4)c3)cccc12 CHEMBL471335 IC50 140.0 nM
C[C@@H]1Cn2ncc(-c3ccc(S(C)(=O)=O)cc3)c2CN1c1ccnc2[nH]ccc12 CHEMBL3355072 IC50 140.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCOCC2)c(=O)n4C)cn1 CHEMBL3960662 IC50 140.0 nM
Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 CHEMBL16687 IC50 140.0 nM
N#CCCCCn1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242470 IC50 149.0 nM
COc1ccc(-c2nn(C)c3ncnc(N)c23)cc1O CHEMBL1241301 IC50 150.0 nM
Nc1ncnc2[nH]nc(-c3ccc4ccccc4c3)c12 CHEMBL1241441 IC50 150.0 nM
Cn1nc(-c2ccc3cc[nH]c3c2)c2c(N)ncnc21 CHEMBL1240566 IC50 150.0 nM
COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)c3ccc(C)c(OC)c3)cc2)cc(OC)c1 CHEMBL3349370 IC50 150.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@H]1CCOC1 CHEMBL1242748 IC50 151.0 nM
COC[C@@H](C)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4752634 IC50 153.0 nM
FC(F)c1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4877926 IC50 153.0 nM
COc1ccc(-c2nn(C3CCC(C)C3)c3ncnc(N)c23)cc1O CHEMBL1242202 IC50 155.0 nM
CS(=O)(=O)c1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4873491 IC50 156.0 nM
O=c1cc(-c2ccc(-c3csc4ccccc34)cc2)sc(N2CCOCC2)c1 CHEMBL102581 IC50 160.0 nM
O=c1cc(-c2ccc(-c3cccc4ccccc34)cc2)sc(N2CCOCC2)c1 CHEMBL105678 IC50 160.0 nM
O=C(CN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)cc1OCC1CCC1 CHEMBL1669165 IC50 160.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4872830 Ki 160.0 nM
COc1ccc(Nc2cc(-c3ncnc4cc(N5CCOCC5)ccc34)c(F)cc2Cl)nn1 CHEMBL5186964 IC50 165.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2CC1CCNC1 CHEMBL1241770 IC50 169.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ncc(-c4ccncc4)s3)cccc12 CHEMBL454660 IC50 170.0 nM
C=CCOc1cc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)ccc1NC(=O)CN1CCOCC1 CHEMBL1669161 IC50 170.0 nM
Cc1ccc(-c2nn(C)c3ncnc(N)c23)cc1O CHEMBL1241271 IC50 173.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2CCC1CCCNC1 CHEMBL1241943 IC50 179.0 nM
O=c1cc(-c2ccc(Cl)cc2)oc(N2CCOCC2)c1 CHEMBL105612 IC50 180.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccccc4)c3)cccc12 CHEMBL512322 IC50 180.0 nM
C[C@H](CN)n1nc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21 CHEMBL1241579 IC50 180.0 nM
CC(C)COc1cc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)ccc1NC(=O)CN1CCOCC1 CHEMBL1669160 IC50 180.0 nM
O=c1cc(N2CCOCC2)cc(N2C[C@H]3C[C@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4874640 Ki 180.0 nM
O=c1cc(-c2cccc3c2Sc2ccccc2S3)oc(N2CCOCC2)c1 CHEMBL222102 IC50 183.0 nM
Cc1cc(-c2nn(C(C)C)c3ncnc(N)c23)sc1C=O CHEMBL1241947 IC50 184.0 nM
Nc1ncnc2c1c(-c1cccc(O)c1F)nn2C1CCCC1 CHEMBL1242111 IC50 185.0 nM
CC(C)n1nc(-c2ccc3[nH]c(=O)[nH]c3c2)c2c(N)ncnc21 CHEMBL1241586 IC50 186.0 nM
CC1CN(c2cc(=O)c3ccc4ccccc4c3o2)CCO1 CHEMBL435507 IC50 190.0 nM
CC(C)n1nc(-c2cccc(O)c2)c2c(N)ncnc21 CHEMBL1230790 IC50 190.0 nM
Cc1cc(O)ccc1-c1nn(C(C)C)c2ncnc(N)c12 CHEMBL1242024 IC50 190.0 nM
CN1CCN(CCOc2ccc3cc4oc(N5CCOCC5)nc(=O)c4cc3c2)CC1 CHEMBL1795752 IC50 190.0 nM
N#CCCCn1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242469 IC50 194.0 nM
CCNc1nc2ccccc2n1-c1nc2c(c(C(C)(C)S(C)(=O)=O)n1)OC[C@@H]1COCCN21 CHEMBL3951757 IC50 196.0 nM
C[C@H](CN1C[C@@H](C)O[C@@H](C)C1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4794132 IC50 198.0 nM
CC(C)n1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1241489 IC50 200.0 nM
O=c1cc(-c2cccc3c2Sc2ccccc2C3)oc(N2CCOCC2)c1 CHEMBL4569967 IC50 204.0 nM
CCn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1242851 IC50 210.0 nM
CNc1nc2ccc(Cl)cc2n1-c1nc2c(c(C3(S(C)(=O)=O)CC3)n1)OC[C@@H]1COCCN21 CHEMBL3904072 IC50 210.0 nM
Cc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1O CHEMBL1242026 IC50 212.0 nM
COc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1O CHEMBL1242114 IC50 212.0 nM
CCn1nc(-c2ccc(OC)c(O)c2)c2c(N)ncnc21 CHEMBL1242113 IC50 214.0 nM
Nc1ncnc2c1c(-c1cnc3ccccc3c1)nn2C1CCCC1 CHEMBL1242755 IC50 214.0 nM
Cc1cncc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4855691 IC50 214.0 nM
CC(C)n1nc(-c2ccc(C=O)c(F)c2)c2c(N)ncnc21 CHEMBL1241860 IC50 216.0 nM
COCOc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1Br CHEMBL1242286 IC50 218.0 nM
COc1ccc(-c2cc(=O)cc(N3CCOCC3)o2)cc1 CHEMBL319261 IC50 220.0 nM
Nc1ncnc2c1c(-c1ccc3occc3c1)nn2C1CCCC1 CHEMBL1241491 IC50 220.0 nM
Cc1cc2ncnn2cc1Nc1ncc2c(n1)C1(CCOCC1)C(=O)N2C(C)C CHEMBL5182910 IC50 220.45 nM
CC(C)n1nc(-c2ccn3ccnc3c2)c2c(N)ncnc21 CHEMBL1242665 IC50 222.0 nM
O=c1cc(N2CCOCC2)oc2c1ccc1ccccc12 CHEMBL104468 IC50 230.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ncc(-c4ccoc4)s3)cccc12 CHEMBL462199 IC50 240.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ncc(-c4ccsc4)s3)cccc12 CHEMBL508976 IC50 240.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CNC1 CHEMBL1242567 IC50 242.0 nM
CCOc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1OC CHEMBL1240554 IC50 242.0 nM
Cn1ccc2cc(-c3nn(C4CCCC4)c4ncnc(N)c34)ccc21 CHEMBL1242385 IC50 244.0 nM
Oc1cc(N2CCOCC2)nc2c3ccccc3cc[n+]12 CHEMBL198675 IC50 250.0 nM
CC(C)n1cc(-c2cccc(O)c2)c2c(N)ncnc21 CHEMBL1241269 IC50 250.0 nM
CC(C)n1nc(-c2cccc(O)c2F)c2c(N)ncnc21 CHEMBL1242110 IC50 251.0 nM
Cc1ccc(-c2ccc(-c3cc(=O)cc(N4CCOCC4)s3)cc2)c2ccccc12 CHEMBL104682 IC50 260.0 nM
S=c1cc(N2CCOCC2)oc2c1ccc1ccccc12 CHEMBL176233 IC50 260.0 nM
COC(=O)c1cc(N)cc(-c2cccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c2)c1 CHEMBL488880 IC50 260.0 nM
CCOc1ccc2cc(-c3nn(C)c4ncnc(N)c34)ccc2c1 CHEMBL1242661 IC50 260.0 nM
CC(C)n1nc(-c2ccc3occc(=O)c3c2)c2c(N)ncnc21 CHEMBL1242118 IC50 260.0 nM
COc1cc(-c2ccc3c(n2)[C@@H](C)N(c2cnn(CC(F)(F)F)c2)C3=O)cnc1OC CHEMBL4126773 Ki 260.0 nM
OCc1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4860637 IC50 266.0 nM
O=c1nc(N2CCOCC2)oc2c(-c3cccc4c3oc3ccccc34)cccc12 CHEMBL3763392 IC50 269.0 nM
O=C(c1ccccc1)c1ccc(N2CCOCC2)cc1O CHEMBL478980 IC50 270.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccoc4)c3)cccc12 CHEMBL487033 IC50 270.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@@H]1CCOC1 CHEMBL1242749 IC50 277.0 nM
O=c1cc(-c2cccc3c2Sc2ccc(OC4COC4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4760480 IC50 278.0 nM
COc1ccc(-c2cc(=O)cc(N3CCOCC3)s2)cc1 CHEMBL321784 IC50 280.0 nM
O=c1cc(N2CCOCC2)nc2c3ccccc3ccn12 CHEMBL179242 IC50 280.0 nM
C#CCn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1242571 IC50 280.0 nM
CCOc1cc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)ccc1NC(=O)CN1CCOCC1 CHEMBL1669158 IC50 280.0 nM
Cc1c(OCc2cccnc2)ccc2c(=O)nc(N3CCOCC3)oc12 CHEMBL1276684 IC50 280.0 nM
Cn1nc(-c2ccc3occc(=O)c3c2)c2c(N)ncnc21 CHEMBL1242117 IC50 283.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4792737 IC50 285.0 nM
CC(C)n1nc(-c2cc3cc(C=O)ccc3s2)c2c(N)ncnc21 CHEMBL1241684 IC50 288.0 nM
COc1cc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)ccc1NC(=O)CN1CCOCC1 CHEMBL1669156 IC50 290.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccsc3)cccc12 CHEMBL360183 IC50 300.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3cc(-c4ccsc4)ccn3)cccc12 CHEMBL460952 IC50 300.0 nM
O=c1nc(N2CCOCC2)oc2c(-c3ccccc3)cccc12 CHEMBL243810 IC50 300.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccccc3)cccc12 CHEMBL98350 IC50 300.0 nM
COc1ccc(C2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)cc1 CHEMBL3947076 IC50 300.0 nM
c1ccc([C@@H]2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)cc1 CHEMBL4107777 IC50 300.0 nM
c1nc(N2CCCC2)c2ccc(N3CCOCC3)cc2n1 CHEMBL3904662 IC50 300.0 nM
c1nc(N2CCCCCC2)c2ccc(N3CCOCC3)cc2n1 CHEMBL3972300 IC50 300.0 nM
c1ccc(C[C@@H]2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)cc1 CHEMBL3963033 IC50 300.0 nM
CC1CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1 CHEMBL3958133 IC50 300.0 nM
O=C(c1ccc(F)cc1)C1CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1 CHEMBL3968049 IC50 300.0 nM
CCOCC1CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1 CHEMBL3973414 IC50 300.0 nM
O=C(C1CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1)N1CCCCC1 CHEMBL3911535 IC50 300.0 nM
c1ccc2oc(C3CCCN(c4ncnc5cc(N6CCOCC6)ccc45)C3)nc2c1 CHEMBL3913280 IC50 300.0 nM
FC(F)(F)c1cccc(C2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)c1 CHEMBL3914444 IC50 300.0 nM
c1ccc2sc(CC3CCCN(c4ncnc5cc(N6CCOCC6)ccc45)C3)cc2c1 CHEMBL3891299 IC50 300.0 nM
C1=C(c2cccs2)CN(c2ncnc3cc(N4CCOCC4)ccc23)CC1 CHEMBL3918077 IC50 300.0 nM
COc1ccc(CC2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)cc1OC CHEMBL3920557 IC50 300.0 nM
c1ccc2sc(CC3CCCN(c4ncnc5cc(N6CCOCC6)ccc45)C3)nc2c1 CHEMBL3906600 IC50 300.0 nM
Cn1ccnc1C(O)C1CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1 CHEMBL3970834 IC50 300.0 nM
N#Cc1nc(N2CCCCC2)c2ccc(N3CCOCC3)cc2n1 CHEMBL3971930 IC50 300.0 nM
O=C(NC1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1)c1cscn1 CHEMBL3966339 IC50 300.0 nM
CN(C(=O)c1cncs1)C1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1 CHEMBL3941003 IC50 300.0 nM
O=C(NC1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1)c1cccs1 CHEMBL3935058 IC50 300.0 nM
CC(C)n1nc(-c2ccc3occc3c2)c2c(N)ncnc21 CHEMBL1241490 IC50 303.0 nM
CC(C)n1nc(-c2cc(O)cc(Br)c2)c2c(N)ncnc21 CHEMBL1242285 IC50 309.0 nM
COc1ccccc1-c1cc(=O)cc(N2CCOCC2)o1 CHEMBL105256 IC50 310.0 nM
CC(C)n1nc(-c2ccc3nc(NN)ccc3c2)c2c(N)ncnc21 CHEMBL1241950 IC50 314.0 nM
CC(C)n1nc(-c2cnc3ccccc3c2)c2c(N)ncnc21 CHEMBL1242754 IC50 317.0 nM
CCOC(Cn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21)OCC CHEMBL3800481 IC50 320.0 nM
O=c1oc(N2CCOCC2)cc2c(-c3cccc4c3oc3ccccc34)cccc12 CHEMBL1082378 IC50 330.0 nM
CC(C)Oc1cc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)ccc1NC(=O)CN1CCOCC1 CHEMBL1669159 IC50 330.0 nM
O=c1nc(N2CCOCC2)oc2cc3c(OCc4cccnc4)cccc3cc12 CHEMBL1795750 IC50 330.0 nM
Clc1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4862738 IC50 330.0 nM
COc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1 CHEMBL1242847 IC50 331.0 nM
C[C@@H]1COCCN1c1cc(-c2ccnn2C)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4647810 IC50 332.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCC1 CHEMBL1242566 IC50 336.0 nM
CCC(C)n1nc(-c2ccc(C)c(O)c2)c2c(N)ncnc21 CHEMBL1242109 IC50 336.0 nM
CC(C)n1nc(-c2cccc(C(=O)NC3=NCCS3)c2)c2c(N)ncnc21 CHEMBL1242115 IC50 339.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ccc(-c4ccc5[nH]ccc5c4)s3)cccc12 CHEMBL453884 IC50 340.0 nM
O=c1oc(N2CCOCC2)cc2c(-c3cccc4c3sc3ccccc34)cccc12 CHEMBL1082377 IC50 340.0 nM
Nc1ncnc2c1c(-c1ccc3ccccc3c1)nn2CCc1ccccc1 CHEMBL1242382 IC50 340.0 nM
CC(C)n1nc(-c2ccc3c(ccn3C)c2)c2c(N)ncnc21 CHEMBL1242384 IC50 349.0 nM
O=c1cc(-c2cccc(-c3ccc(O)cc3)c2)sc(N2CCOCC2)c1 CHEMBL104450 IC50 350.0 nM
O=c1cc(-c2ccc(F)cc2)oc(N2CCOCC2)c1 CHEMBL105521 IC50 350.0 nM
O=C1c2ccccc2C(=O)N1CCCOc1ccc2c(=O)cc(N3CCOCC3)oc2c1 CHEMBL198482 IC50 350.0 nM
C=CCn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1241488 IC50 350.0 nM
N=C(N)NCCCC(NC(=O)CCC(=O)OC[N+]1(c2cc(=O)c3cccc(-c4ccccc4)c3o2)CCOCC1)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)[O-] CHEMBL3218580 IC50 357.0 nM
Cc1ccc2ccc(-c3nn(C(C)C)c4ncnc(N)c34)cc2n1 CHEMBL1242209 IC50 359.0 nM
O=c1cc(N2CCOCC2)oc2c3c(ccc12)CCCC3 CHEMBL179108 IC50 360.0 nM
Cc1ccsc1-c1cccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c1 CHEMBL521403 IC50 360.0 nM
O=c1nc(N2CCOCC2)oc2c(OCc3cccnc3)cccc12 CHEMBL1276718 IC50 360.0 nM
CC(C)n1nc(-c2cccc(NS(C)(=O)=O)c2)c2c(N)ncnc21 CHEMBL1241948 IC50 365.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2CC1CCCN1 CHEMBL1241769 IC50 367.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ncc(-c4ccccc4)s3)cccc12 CHEMBL454658 IC50 370.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCCCCC1 CHEMBL1242750 IC50 370.0 nM
COCc1ccc(-c2cc3c(N[C@@H](C)c4ccn(C)n4)c(C(N)=O)cnc3cc2F)cn1 CHEMBL4166405 IC50 370.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3ccccc3)ccc12 CHEMBL95298 IC50 380.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccco4)c3)cccc12 CHEMBL487032 IC50 380.0 nM
CCOc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1O CHEMBL1242289 IC50 383.0 nM
O=c1cc(N2CCOCC2)oc2cc3ccccc3cc12 CHEMBL175883 IC50 390.0 nM
O=c1cc(-c2ccccc2F)oc(N2CCOCC2)c1 CHEMBL224092 IC50 390.0 nM
O=c1cc(-c2ccc3[nH]ccc3c2)oc(N2CCOCC2)c1 CHEMBL222745 IC50 400.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ccc(-c4ccccc4)s3)cccc12 CHEMBL454423 IC50 400.0 nM
Nc1ccc(-c2n[nH]c3ncnc(N)c23)cc1 CHEMBL1241356 IC50 400.0 nM
Nc1ncnc2c1c(-c1ccc3ccccc3c1)nn2CC1CC1 CHEMBL1242473 IC50 400.0 nM
O=Cc1ccc(N2CCOCC2)cc1O CHEMBL2181110 IC50 400.0 nM
Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2CC1CCNCC1 CHEMBL1241859 IC50 408.0 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 IC50 410.0 nM
CC(C)n1nc2ncnc(N)c2c1C1C=c2cc(O)ccc2=N1 CHEMBL5285509 IC50 410.0 nM
CC(C)(C)n1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1231371 IC50 420.0 nM
O=c1nc(N2CCOCC2)oc2c1ccc1ccccc12 CHEMBL1795743 IC50 420.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCCCC4)nc3)cc2n1 CHEMBL5419324 IC50 420.0 nM
Cc1cc([C@@H](C)Nc2ccccc2C(=O)O)c2nc(N3CCOCC3)cc(=O)n2c1 CHEMBL2165191 IC50 420.0 nM
CC(C)n1nc(-c2ccc3c(ccn3C(=O)OC(C)(C)C)c2)c2c(N)ncnc21 CHEMBL1242852 IC50 430.0 nM
COc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1OC CHEMBL1242290 IC50 439.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3ccc(F)cc3)ccc12 CHEMBL197004 IC50 440.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3ccc4ccccc4c3)ccc12 CHEMBL197379 IC50 440.0 nM
Nc1ncnc2[nH]nc(-c3cccc(O)c3)c12 CHEMBL1241242 IC50 440.0 nM
O=c1cc(N2CCOCC2)oc2cc(O)ccc12 CHEMBL197536 IC50 450.0 nM
COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1O CHEMBL1242112 IC50 460.0 nM
COc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1OC CHEMBL1240553 IC50 463.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCCS(=O)(=O)c3ccccc3)ccc12 CHEMBL427194 IC50 470.0 nM
O=c1cc(N2CCOCC2)cc(-c2ccc(Cl)cc2)o1 CHEMBL222821 IC50 470.0 nM
Cc1ccc(-c2n[nH]c3ncnc(N)c23)cc1O CHEMBL1241270 IC50 478.0 nM
CC(C)(C)c1ccc(-c2cc(=O)cc(N3CCOCC3)o2)cc1 CHEMBL102529 IC50 480.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ncc(-c4cccs4)s3)cccc12 CHEMBL454659 IC50 480.0 nM
CC(C)n1nc(-c2ccc3c(c2)OCCO3)c2c(N)ncnc21 CHEMBL1241588 IC50 489.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3cccc(Cl)c3)ccc12 CHEMBL198576 IC50 490.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4nccs4)c3)cccc12 CHEMBL488903 IC50 490.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3ccc(Cl)cc3)ccc12 CHEMBL199577 IC50 500.0 nM
O=C1c2ccccc2C(=O)N1Cc1ccc(-c2cc(=O)cc(N3CCOCC3)o2)cc1 CHEMBL374290 IC50 500.0 nM
C[C@@H](CN)n1nc(-c2ccc(F)c(O)c2)c2c(N)ncnc21 CHEMBL1242468 IC50 500.0 nM
O=C(CN1CCOCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)cc1OCCC1CC1 CHEMBL1669166 IC50 500.0 nM
Cc1c(OCCN2CCN(C)CC2)ccc2c(=O)nc(N3CCOCC3)oc12 CHEMBL244672 IC50 500.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL3747513 IC50 500.0 nM
FC(F)(F)Oc1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4878956 IC50 507.0 nM
COc1cc(-c2nn(C3CCCC3)c3ncnc(N)c23)ccc1N CHEMBL1241581 IC50 509.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ncc(-c4cccnc4)s3)cccc12 CHEMBL518820 IC50 510.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccncc4)c3)cccc12 CHEMBL503589 IC50 510.0 nM
Nc1cc(C(=O)O)cc(-c2cccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c2)c1 CHEMBL486876 IC50 510.0 nM
O=c1cc(-c2cccc(F)c2)oc(N2CCOCC2)c1 CHEMBL319909 IC50 530.0 nM
O=c1cc(-c2ccc(Cl)cc2)sc(N2CCOCC2)c1 CHEMBL323136 IC50 530.0 nM
COc1ccc(-c2cc(N3CCOCC3)cc(=O)o2)cc1 CHEMBL221410 IC50 530.0 nM
COc1cccc(-c2cc(=O)cc(N3CCOCC3)o2)c1 CHEMBL106543 IC50 540.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@H]1CCNC1 CHEMBL1242657 IC50 543.0 nM
CC(C)n1nc(-c2ccc3c(c2)CCO3)c2c(N)ncnc21 CHEMBL1241587 IC50 546.0 nM
C=CCn1nc(-c2ccc(OCC)c(OC)c2)c2c(N)ncnc21 CHEMBL1242569 IC50 556.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3ccc(Br)cc3)ccc12 CHEMBL372143 IC50 560.0 nM
O=c1nc(N2CCOCC2)oc2c(-c3cccc4c3sc3ccccc34)cc(Cl)cc12 CHEMBL3763722 IC50 564.0 nM
CC(C)n1nc(-c2ccc(C(N)=O)c(Cl)c2)c2c(N)ncnc21 CHEMBL1241862 IC50 565.0 nM
COc1ccc(-c2n[nH]c3ncnc(N)c23)cc1O CHEMBL1241300 IC50 576.0 nM
Nc1ncc(-c2nc(N3CCOCC3)c3ccn(CCCCCCC(=O)NO)c3n2)cn1 CHEMBL4744689 IC50 594.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccc(CO)cc3)cccc12 CHEMBL189552 IC50 600.0 nM
O=c1cc(-c2cc3ccccc3s2)oc(N2CCOCC2)c1 CHEMBL222544 IC50 600.0 nM
O=c1cc(N2CCOCC2)c2ccc(-c3cccs3)cc2o1 CHEMBL1085747 IC50 600.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ccnc(-c4ccc5cc[nH]c5c4)c3)cccc12 CHEMBL462200 IC50 610.0 nM
Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2[C@@H]1CCNC1 CHEMBL1242658 IC50 610.0 nM
CC(C)n1nc(-c2ccc(O)cc2)c2c(N)ncnc21 CHEMBL1241241 IC50 620.0 nM
Nc1ncc(-c2ccccc2)nc1C(=O)Nc1ccccc1 CHEMBL1766759 IC50 620.0 nM
O=c1nc(N2CCOCC2)oc2c(OCc3ccccn3)cccc12 CHEMBL2204545 IC50 620.0 nM
CCOc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1OC CHEMBL1242752 IC50 630.0 nM
NC(=O)Cn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 CHEMBL1242383 IC50 630.0 nM
Cc1cscc1-c1cccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c1 CHEMBL488213 IC50 640.0 nM
COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1N CHEMBL1241485 IC50 640.0 nM
COCc1ccc(-c2ccc3ncc(C(N)=O)c(N[C@@H](C)C4CCOCC4)c3c2)cn1 CHEMBL4218734 IC50 643.0 nM
O=c1cc(-c2ccccc2)sc(N2CCOCC2)c1 CHEMBL276746 IC50 650.0 nM
COc1ccc(-c2nn(C[C@@H](C)CO)c3ncnc(N)c23)cc1OC CHEMBL1242381 IC50 660.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1cccc(S(C)(=O)=O)c1)C2(C)C CHEMBL5423608 IC50 662.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ccnc(-c4ccccc4)c3)cccc12 CHEMBL452577 IC50 670.0 nM
Nc1ncnc2[nH]nc(-c3cccc(OCc4ccccc4)c3)c12 CHEMBL1242291 IC50 670.0 nM
O=c1cc(-c2ccc(Br)cc2)sc(N2CCOCC2)c1 CHEMBL316769 IC50 680.0 nM
CC(=O)Nc1cccc(-c2cccc(-c3cc(=O)cc(N4CCOCC4)s3)c2)c1 CHEMBL222820 IC50 680.0 nM
O=c1oc(N2CCOCC2)cc2c(-c3cccc(-c4ccccc4)c3)cccc12 CHEMBL1084237 IC50 680.0 nM
COc1ccc(-c2nn(C3CNC3)c3ncnc(N)c23)cc1O CHEMBL1242203 IC50 683.0 nM
N#Cc1ccc(COc2ccc3c(=O)cc(N4CCOCC4)oc3c2)cc1 CHEMBL371947 IC50 690.0 nM
CC1(COc2cc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)ccc2NC(=O)CN2CCOCC2)COC1 CHEMBL1669155 IC50 690.0 nM
CN(C)C(=O)c1cc(CN2CCOc3c(F)cccc32)c2oc(N3CCOCC3)cc(=O)c2c1 CHEMBL3799831 IC50 690.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccs3)cccc12 CHEMBL362729 IC50 700.0 nM
O=c1cc(-c2cccc(Br)c2)sc(N2CCOCC2)c1 CHEMBL323145 IC50 700.0 nM
COc1ccc(-c2nn(C[C@H](C)CO)c3ncnc(N)c23)cc1OC CHEMBL1242380 IC50 709.0 nM
CSc1ccc(COc2ccc3c(=O)cc(N4CCOCC4)oc3c2)cc1 CHEMBL201988 IC50 710.0 nM
O=c1cc(N2CCCCC2)oc2c(-c3ccc(-c4cccc5cnccc45)s3)cccc12 CHEMBL454429 IC50 710.0 nM
CC(C)n1nc(-c2cccc(S(N)(=O)=O)c2)c2c(N)ncnc21 CHEMBL1242031 IC50 713.0 nM
CC(C)n1nc(-c2ccc(N)c(O)c2)c2c(N)ncnc21 CHEMBL1242848 IC50 717.0 nM
O=c1nc(N2CCOCC2)oc2c1cc(OCc1cccnc1)c1ccccc12 CHEMBL1795746 IC50 717.0 nM
N#Cc1ccccc1-c1cnc(N)c(C(=O)Nc2ccccc2)n1 CHEMBL1766765 IC50 720.0 nM
O=c1nc(N2CCOCC2)oc2ccc3ccccc3c12 CHEMBL1795742 IC50 720.0 nM
CC(C)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21 CHEMBL1242198 IC50 735.0 nM
CC(C)n1nc(-c2cc(C=O)co2)c2c(N)ncnc21 CHEMBL1241439 IC50 737.0 nM
CS(=O)(=O)c1cccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)c1 CHEMBL1766773 IC50 740.0 nM
CC(C)(c1nc(-[n+]2c(N)[nH]c3ccccc32)nc2c1OC[C@@H]1COCCN21)S(C)(=O)=O CHEMBL4110558 IC50 741.0 nM
Fc1ccc2[nH]cc(C3CCCN(c4ncnc5cc(N6CCOCC6)ccc45)C3)c2c1 CHEMBL3895709 IC50 750.0 nM
c1nc(N2CCCC(CC3CCCCC3)C2)c2ccc(N3CCOCC3)cc2n1 CHEMBL3966993 IC50 750.0 nM
OC1(c2ccccc2)CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1 CHEMBL3934926 IC50 750.0 nM
NC(=O)C1CCCN(c2ncnc3cc(N4CCOCC4)ccc23)C1 CHEMBL3943898 IC50 750.0 nM
Cc1noc(C2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)n1 CHEMBL3984779 IC50 750.0 nM
c1nc(N2CCCC(CN3CCOCC3)C2)c2ccc(N3CCOCC3)cc2n1 CHEMBL3895970 IC50 750.0 nM
c1ccc2[nH]c(C3CCCN(c4ncnc5cc(N6CCOCC6)ccc45)C3)nc2c1 CHEMBL3900777 IC50 750.0 nM
Nc1nc(N2CCCCC2)c2ccc(N3CCOCC3)cc2n1 CHEMBL3942323 IC50 750.0 nM
CN(C(=O)c1nccs1)C1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1 CHEMBL3895022 IC50 750.0 nM
CN1CCN(CCOc2cc3c(=O)nc(N4CCOCC4)oc3c3ccccc23)CC1 CHEMBL1795751 IC50 760.0 nM
Nc1ncnc2c1c(-c1ccc3ccccc3c1)nn2C1CCCC1 CHEMBL1241584 IC50 780.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc([C@H](C)N)cc4)no3)n2)cc1 CHEMBL4467848 Ki 785.0 nM
COc1ncc(-c2nn(C(C)C)c3ncnc(N)c23)c(OC)n1 CHEMBL1242846 IC50 789.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCc3ccccc3Cl)ccc12 CHEMBL198138 IC50 790.0 nM
CC(=O)c1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)s1 CHEMBL187562 IC50 800.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cc4ccccc4s3)cccc12 CHEMBL362521 IC50 800.0 nM
Cc1cccc(COc2ccc3c(=O)cc(N4CCOCC4)oc3c2)c1 CHEMBL196870 IC50 800.0 nM
O=c1cc(-c2ccc(-c3ccccc3)cc2)oc(N2CCOCC2)c1 CHEMBL426894 IC50 800.0 nM
O=c1cc(-c2cc3ccccc3o2)oc(N2CCOCC2)c1 CHEMBL222545 IC50 800.0 nM
COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1F CHEMBL1241483 IC50 824.0 nM
COc1cc(Br)cc(-c2nn(C(C)C)c3ncnc(N)c23)c1 CHEMBL1242200 IC50 826.0 nM
COc1ccc(-c2cccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c2)cc1 CHEMBL513231 IC50 830.0 nM
COC(=O)/C=C/c1ccccc1-c1cccc(-c2cc(=O)cc(N3CCOCC3)s2)c1 CHEMBL431228 IC50 840.0 nM
COC(=O)c1cccc(COc2ccc3c(=O)cc(N4CCOCC4)oc3c2)c1 CHEMBL372627 IC50 840.0 nM
CCOc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1OC CHEMBL1242472 IC50 847.0 nM
Cn1nc(-c2cccc(-c3ccccc3)c2)c2c(N)ncnc21 CHEMBL1242849 IC50 860.0 nM
COc1cc(F)c(-c2nn(C(C)C)c3ncnc(N)c23)cc1F CHEMBL1242027 IC50 873.0 nM
COc1cc2ncnc(-n3nc(-c4ccccn4)nc3N)c2cc1OC CHEMBL2143829 IC50 879.0 nM
O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccccn4)c3)cccc12 CHEMBL529668 IC50 880.0 nM
Nc1ncnc2[nH]nc(-c3ccc4c(c3)OCO4)c12 CHEMBL1240567 IC50 880.0 nM
CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1 CHEMBL3643413 IC50 880.0 nM
CC(C)n1nc(-c2cccc(CC#N)c2)c2c(N)ncnc21 CHEMBL1241583 IC50 883.0 nM
CC(C)(O)c1nc(-c2cc(F)cc3[nH]ccc23)nc2c1OC[C@@H]1COCCN21 CHEMBL3925064 IC50 886.0 nM
CC(C)n1nc(-c2ccc(S(N)(=O)=O)cc2)c2c(N)ncnc21 CHEMBL1242032 IC50 894.0 nM
COc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)cc1 CHEMBL363755 IC50 900.0 nM
O=c1cc(-c2cccc3cccnc23)oc(N2CCOCC2)c1 CHEMBL223041 IC50 900.0 nM
O=c1cc(-c2ccc(OCc3ccccc3)cc2)oc(N2CCOCC2)c1 CHEMBL225796 IC50 910.0 nM
CC(C)(C)OC(=O)n1ccc2cc(-c3nn(C4CCCC4)c4ncnc(N)c34)ccc21 CHEMBL1242853 IC50 916.0 nM
Nc1ncnc2c1c(-c1cc(O)cc(F)c1)nn2C1CCCC1 CHEMBL1242199 IC50 919.0 nM
CC(C)(C)c1ccc(-c2cc(=O)cc(N3CCOCC3)s2)cc1 CHEMBL102396 IC50 920.0 nM
O=c1cc(-c2cccc(-c3cccc(O)c3)c2)sc(N2CCOCC2)c1 CHEMBL104644 IC50 920.0 nM
Nc1ncnc2c1c(-c1cccc3[nH]ccc13)nn2C1CCCC1 CHEMBL1242758 IC50 929.0 nM
O=c1nc(N2CCOCC2)oc2cc3c(OCc4ccccn4)cccc3cc12 CHEMBL1795749 IC50 930.0 nM
O=c1cc(N2CCOCC2)oc2cc(OCC3CCCCC3)ccc12 CHEMBL372830 IC50 940.0 nM
COc1ccc2c(=O)cc(N3CCOCC3)oc2c1 CHEMBL175459 IC50 950.0 nM
CC(C)n1nc(-c2cccc3[nH]ccc23)c2c(N)ncnc21 CHEMBL1242757 IC50 953.0 nM
COc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2OC)=NC3)ccc1C(=O)O CHEMBL483158 Kdapp 962.0 nM
CC(C)n1nc(-c2ccc(NS(C)(=O)=O)cc2)c2c(N)ncnc21 CHEMBL1242030 IC50 979.0 nM
CS(=O)(=O)C1(c2nc(-c3cc(F)cc4[nH]ccc34)nc3c2OC[C@@H]2COCCN32)CC1 CHEMBL3948778 IC50 989.0 nM