CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL1980995 pKi 0.3162 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(Cl)c4)c3)cc12 CHEMBL1974870 pKi 1.0 nM
NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL1998121 pKi 1.0 nM
O=C(NCc1ccc(Br)cc1)Nc1ccc2[nH]ncc2c1 CHEMBL1970709 pKi 1.259 nM
O=C(NC(CO)c1ccccc1)c1ccc(-c2ccncc2)cc1 CHEMBL1974288 pKi 1.259 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 1.39 nM
O=C(NCc1ccc(Cl)c(Cl)c1)Nc1ccc2[nH]ncc2c1 CHEMBL1981782 pKi 1.585 nM
O=C1NN=Cc2c[nH]c3cc(NC(=O)C4CC4c4ccccc4)cc1c23 CHEMBL1969502 pKi 1.585 nM
N#Cc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1 CHEMBL1990162 pKi 1.585 nM
CC(C)(CN)CNc1nc(Cl)cc(-c2c[nH]c3ncccc23)n1 CHEMBL1968930 pKi 1.995 nM
Cc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccc(F)cc3)cc12 CHEMBL1972339 pKi 2.512 nM
CC(NC(=O)c1ccc(-c2ccncc2)cc1)c1ccccc1 CHEMBL1999428 pKi 2.512 nM
NCCNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL1972290 pKi 3.162 nM
NCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL592030 pKi 3.162 nM
NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1973720 pKi 3.162 nM
O=c1c(NCc2ccc(Cl)c(Cl)c2)c(Nc2ccncc2)c1=O CHEMBL1975900 pKi 3.981 nM
NC1CCCCC1Nc1nc(Cl)cc(-c2c[nH]c3ncccc23)n1 CHEMBL1994438 pKi 3.981 nM
CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21 CHEMBL494089 IC50 5.0 nM
Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3I)cc12 CHEMBL1975128 pKi 5.012 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(OC(F)(F)F)c4)c3)cc12 CHEMBL1965836 pKi 5.012 nM
NC1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1998432 pKi 5.012 nM
NC1CCC(Nc2nccc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1966628 pKi 6.31 nM
Cc1cc(O)nc2[nH]nc(-c3cccc(-c4ccc(Cl)cc4)c3)c12 CHEMBL1990590 pKi 6.31 nM
NC(COc1cncc(-c2ccc3cnccc3c2)c1)Cc1c[nH]c2ccccc12 CHEMBL1981133 pKi 6.31 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1ccc(Cl)cc1 CHEMBL1987073 pKi 6.31 nM
O=C(NCc1ccccc1)c1ccc(-c2ccncc2)cc1 CHEMBL1977135 pKi 7.943 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 7.943 nM
CC(C)(CN)CNc1cc(-c2c[nH]c3ncccc23)cc(F)n1 CHEMBL1987261 pKi 10.0 nM
CN(C)CC(=O)NC1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1995712 pKi 10.0 nM
CN(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1 CHEMBL1996111 pKi 10.0 nM
CC(C)N(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1 CHEMBL1969561 pKi 12.59 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1ccc(F)cc1 CHEMBL1966204 pKi 12.59 nM
CN(C)c1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1 CHEMBL1992363 pKi 12.59 nM
Cc1cncc2cccc(S(=O)(=O)N3CCCNCC3C)c12 CHEMBL1082440 pKi 15.85 nM
NC(COCc1ccccc1)COc1cncc(C=Cc2ccncc2)c1 CHEMBL1993781 pKi 19.95 nM
CC(C)(CN)CNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL1985723 pKi 19.95 nM
Cn1cc(Nc2ncc(Br)c(Nc3ccccc3C(N)=O)n2)cn1 CHEMBL1994669 pKi 19.95 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)N3CCC(N)C3)c21 CHEMBL1870106 pKi 19.95 nM
OC1CCCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1976936 pKi 19.95 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccccc4)c3)cc12 CHEMBL2002726 pKi 19.95 nM
Nc1nnc(-c2cc3c(Oc4ccc(Cl)cc4)cncc3s2)o1 CHEMBL1994830 pKi 19.95 nM
COc1ccc(CNc2cc(-c3c[nH]c4ncccc34)cc(F)n2)cc1 CHEMBL1986855 pKi 19.95 nM
NC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1983589 pKi 25.12 nM
CS(=O)(=O)NCCNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL2005718 pKi 25.12 nM
CC(C)CNC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL2006456 pKi 25.12 nM
CN(C)c1cccc2c(S(=O)(=O)N(CCN)c3cncc(-c4ccc5cnccc5c4)c3)cccc12 CHEMBL1967544 pKi 25.12 nM
CN(C)C1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1969151 pKi 25.12 nM
NC(COc1cncc(C=Cc2ccncc2)c1)Cc1c[nH]c2ccccc12 CHEMBL1974935 pKi 25.12 nM
NC1CCCCC1Nc1nccc(-c2c[nH]c3ncccc23)n1 CHEMBL1995813 pKi 31.62 nM
CC(N)COc1cnc(Cl)c(C=Cc2ccncc2)c1 CHEMBL1993548 pKi 31.62 nM
CNCC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1996980 pKi 31.62 nM
Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL1987448 pKi 31.62 nM
CN(C)CC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1982271 pKi 31.62 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccc[nH]2)C(=O)N3)c1)Cc1ccccc1 CHEMBL1980407 pKi 39.81 nM
CN(C)C1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1965702 pKi 39.81 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL1975121 pKi 39.81 nM
Cn1cc(Nc2ncc(Cl)c(Nc3ccccc3C(N)=O)n2)cn1 CHEMBL1984548 pKi 39.81 nM
O=C(Nc1ccc(-c2ccc3cn[nH]c3c2)cc1)Nc1cccc(F)c1 CHEMBL1969942 pKi 39.81 nM
NC(=O)Cn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL1985095 pKi 39.81 nM
COc1cccc(C(C)NC(=O)N2CC=C(c3c[nH]c4ncccc34)CC2)c1 CHEMBL1965845 pKi 39.81 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3C)cc2)c1 CHEMBL1970217 pKi 39.81 nM
CNC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL2005509 pKi 39.81 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 42.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 43.0 nM
CCCC(=O)Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccccc3)cc12 CHEMBL2005936 pKi 50.12 nM
CC(C)(CNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1)CNS(C)(=O)=O CHEMBL1971172 pKi 50.12 nM
COCCN(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1 CHEMBL1986970 pKi 50.12 nM
Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccccc3)cc12 CHEMBL1972158 pKi 50.12 nM
O=S(=O)(c1cccc2cnccc12)N1CCCNCC1 CHEMBL38380 pKi 50.12 nM
CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc21 CHEMBL220241 pKi 50.12 nM
COc1ccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)cc1OC CHEMBL1991078 pKi 50.12 nM
Cc1n[nH]c2ccc(-c3cncc(OCCN)c3)cc12 CHEMBL1967887 pKi 50.12 nM
Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccc(F)cc3)cc12 CHEMBL1986499 pKi 50.12 nM
c1cc2c(s1)CCc1cn[nH]c1-2 CHEMBL2001539 pKi 50.12 nM
c1ccc(CNc2nc(-c3ccc4[nH]ncc4c3)cs2)cc1 CHEMBL1682546 pKi 50.12 nM
OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1986943 pKi 63.1 nM
CC(=O)Nc1cccc(CNc2c(Nc3ccc4[nH]ncc4c3)c(=O)c2=O)c1 CHEMBL1988608 pKi 63.1 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)c(C)c2)c1 CHEMBL1969049 pKi 63.1 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 CHEMBL1970903 pKi 63.1 nM
CCNC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1992220 pKi 63.1 nM
O=c1[nH]ccc2cc(O[C@H]3CCCNC3)ccc12 CHEMBL1667967 pIC50 79.43 nM
CS(=O)(=O)NC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL2005216 pKi 79.43 nM
Clc1cc(-c2c[nH]c3ncccc23)cc(NCc2ccccc2)n1 CHEMBL1969588 pKi 79.43 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1ccccc1 CHEMBL1999931 pKi 79.43 nM
Cc1n[nH]c2ccc(-c3cncc(OC[C@@H](N)Cc4ccccc4)c3)cc12 CHEMBL379218 Kd 97.0 nM
COc1cccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 CHEMBL1980435 pKi 100.0 nM
CC(=O)NC1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1980178 pKi 100.0 nM
O=C(NCc1ccc(Cl)cc1)c1cc2c(-c3ccccc3)n[nH]c2s1 CHEMBL1967094 pKi 100.0 nM
Nc1nc(Cl)cc(-c2c[nH]c3ncccc23)n1 CHEMBL2007574 pKi 100.0 nM
CC(C)(C)OC(=O)n1ncc2cc(Nc3c(NCc4ccc(S(N)(=O)=O)cc4)c(=O)c3=O)ccc21 CHEMBL1969506 pKi 100.0 nM
Cc1c(O)ccc2c1CCCC2=NNC(=O)Cc1cccc2ccccc12 CHEMBL1972659 pKi 100.0 nM
CN(C)CC(=O)NC(COc1cncc(-c2ccc3cnccc3c2)c1)Cc1c[nH]c2ccccc12 CHEMBL1991725 pKi 100.0 nM
COc1cccc(CNC(=O)c2cc3c(-c4ccccc4)n[nH]c3s2)c1 CHEMBL1987009 pKi 100.0 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 100.0 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)c(F)c2)c1 CHEMBL2004934 pKi 125.89 nM
COc1ccc(C(=O)N2c3ccccc3Sc3c(Cl)cncc32)cc1 CHEMBL1988537 pKi 125.89 nM
O=C(NC(CO)c1cc(Cl)cc(Cl)c1)c1ccc(-c2ccncc2)cc1 CHEMBL2003341 pKi 125.89 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)cc2NCCCN)c1 CHEMBL2006188 pKi 125.89 nM
Cc1ccccc1-c1c(-c2ccc3[nH]nc(N)c3c2)nnn1Cc1ccccc1 CHEMBL2000029 pKi 125.89 nM
Cc1nnc(-c2cc3c(Oc4ccc(C(F)(F)F)cc4)cncc3s2)o1 CHEMBL1988153 pKi 125.89 nM
NC(COc1cncc(-c2ccc3c(c2)CC(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL1967302 pKi 158.49 nM
Clc1cc(-c2c[nH]c3ncccc23)nc(NC2CCOCC2)n1 CHEMBL1980253 pKi 158.49 nM
Cc1c(-c2ccc3[nH]nc(N)c3c2)nnn1Cc1ccccc1 CHEMBL1989646 pKi 158.49 nM
O=C(NC(CO)Cc1ccc(Cl)cc1)c1ccc(-c2ccncc2)cc1 CHEMBL1996931 pKi 158.49 nM
O=C(NCCc1cccs1)N1CC=C(c2c[nH]c3ncccc23)CC1 CHEMBL1987535 pKi 158.49 nM
NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(-c3ccncc3)ccc2c1=O CHEMBL340384 pKi 158.49 nM
O=c1nc(-c2cc3c(Oc4ccc(I)cc4)cncc3s2)[nH]o1 CHEMBL497151 pKi 158.49 nM
CCCOc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL2007296 pKi 158.49 nM
O=C(NC(CO)Cc1ccccc1)c1ccc(-c2ccncc2)cc1 CHEMBL1998545 pKi 199.53 nM
Cc1cc(=O)n2ccc(CN(C)C)c(O)c2n1 CHEMBL1988581 pKi 199.53 nM
NC(=O)c1ccc(-c2c[nH]c3nccc(Cl)c23)cc1 CHEMBL1982711 pKi 199.53 nM
CS(=O)(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1980562 pKi 199.53 nM
NC(=O)c1cccc2[nH]c(-c3ccncc3)nc12 CHEMBL1990482 pKi 199.53 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cccc(F)c1 CHEMBL2003638 pKi 199.53 nM
O=C1CCCN1Cc1ccc2c(c1)[nH]c(=O)c1cccn12 CHEMBL539474 pKi 251.19 nM
CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1 CHEMBL1966035 pKi 251.19 nM
c1ccc(CSc2nc(-c3ccncc3)n[nH]2)cc1 CHEMBL1968926 pKi 251.19 nM
Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 CHEMBL1969523 pKi 251.19 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cc(C(=O)O)ccc4F)cc3)c12 CHEMBL1993722 pKi 251.19 nM
NCCOc1cncc(C=Cc2ccncc2)c1 CHEMBL1989518 pKi 316.23 nM
Cc1ccc(-c2cc3c(NCCN)ccc(C(N)=O)c3[nH]2)cc1 CHEMBL1996048 pKi 316.23 nM
Cc1cc(NC(=O)Cc2ccc(-c3cccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL1984363 pKi 316.23 nM
N#Cc1cccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 CHEMBL1977128 pKi 316.23 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(C(=O)NCc4cccc(F)c4)cc2NC3=O)ccc1O CHEMBL2000832 pKi 316.23 nM
Cc1cc(O)ccc1-n1cc(C(=O)NN)c(=O)c2ccc(-c3ccncc3)cc21 CHEMBL2000894 pKi 316.23 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cccc(Cl)c1 CHEMBL1983595 pKi 316.23 nM
CC(C)Nc1c(-c2ccc3[nH]ncc3c2)nc2ncccn12 CHEMBL1682553 pKi 316.23 nM
CC(C)Cc1cc(-c2ccc3[nH]nc(N)c3c2)on1 CHEMBL1966343 pKi 316.23 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C CHEMBL2000335 pKi 316.23 nM
N#CC1=C(N)n2c(sc(=Cc3ccco3)c2=O)=C(C(N)=O)C1c1ccco1 CHEMBL1989805 pKi 316.23 nM
NC(Cc1c[nH]c2ccccc12)C(=O)Nc1cncc(C=Cc2ccncc2)c1 CHEMBL1983945 pKi 316.23 nM
CCOc1ccccc1-c1cccc(-c2n[nH]c3nc(O)cc(C)c23)c1 CHEMBL1983070 pKi 316.23 nM
O=C(NC(CCO)c1ccccc1)c1ccc(-c2ccncc2)cc1 CHEMBL1986143 pKi 316.23 nM
CC1CCN(C(=O)CC#N)CC1c1ncc2cnc3[nH]ccc3n12 CHEMBL1966175 pKi 316.23 nM
CS(=O)(=O)NC1CCCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)C1 CHEMBL1987948 pKi 316.23 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cc(F)ccc1F CHEMBL1995811 pKi 316.23 nM
OCCC(Nc1nc2ccc(-c3ccncc3)cc2s1)c1ccccc1 CHEMBL1982122 pKi 316.23 nM
CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(OC(F)F)c1 CHEMBL4872886 IC50 326.0 nM
Cc1nc2ccc(NS(=O)(=O)c3ccc(N)cc3)cc2nc1C CHEMBL2006263 pKi 398.11 nM
CN1c2ccc(N)cc2C(c2ccccc2)c2cc(N)ccc21 CHEMBL1991734 pKi 398.11 nM
COc1ccc(C2=NNc3cccc4c(OC)ccc2c34)cc1OC CHEMBL1997335 pKi 398.11 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCCCCCCCCN)cnc(N)c34)cc2)c1 CHEMBL1978166 pKi 398.11 nM
C(=Cc1cncc(OC2CCNC2)c1)c1ccncc1 CHEMBL1966087 pKi 398.11 nM
Oc1ccc(-c2n[nH]c(Nc3cccc(Cl)c3)c2-c2ccc(O)cc2)cc1 CHEMBL1985092 pKi 398.11 nM
CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C(C)(C)C CHEMBL1986186 pKi 398.11 nM
Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 CHEMBL1988173 pKi 398.11 nM
COc1cc(-c2csc3c(C=CC(=O)NCCN(C)C)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C CHEMBL1989267 pKi 398.11 nM
CCN(CC)CCNC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)c1 CHEMBL1970290 pKi 398.11 nM
OC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1991674 pKi 398.11 nM
CC1=NN(c2ccc(Cl)c(Cl)c2)C(=O)C1=Cc1c(C)c(C#N)c2nc3ccccc3n2c1O CHEMBL1997349 pKi 398.11 nM
CC(=O)N(c1ccncc1)c1c(NC(C)C(C)(C)C)c(=O)c1=O CHEMBL2005899 pKi 398.11 nM
c1ccc(CNc2nc3ccc(-c4ccncc4)cc3s2)cc1 CHEMBL1983534 pKi 398.11 nM
O=C(NC(CO)Cc1ccccc1)c1ccc(-c2ccncc2)cc1F CHEMBL1969755 pKi 398.11 nM
Nc1n[nH]c2cccc(-c3ccc(F)cc3)c12 CHEMBL1971519 pKi 501.19 nM
CC(N)C1CCC(C(=O)Nc2ccnc3[nH]ccc23)CC1 CHEMBL2002992 pKi 501.19 nM
CCCOc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3F)cc2)c1 CHEMBL1971606 pKi 501.19 nM
O=C(Cc1ccccc1Cl)Nc1ccc2cn[nH]c2c1 CHEMBL1987533 pKi 501.19 nM
NC(=O)c1cccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)c1 CHEMBL1982957 pKi 501.19 nM
COc1cccc(CNC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL2006299 pKi 501.19 nM
Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CHEMBL1967878 pKi 501.19 nM
COc1cc(-c2ccc3c(c2)Nc2ccc([N+](=O)[O-])cc2NC3=O)ccc1O CHEMBL1995740 pKi 501.19 nM
Cc1n[nH]c2sc(C(=O)NCCc3ccc(Cl)cc3)cc12 CHEMBL1998414 pKi 501.19 nM
Clc1cc(NC2CCCCC2)nc(-c2c[nH]c3ncccc23)n1 CHEMBL1997846 pKi 501.19 nM
CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL2334586 IC50 580.0 nM
O=c1[nH]cnc2c1sc1c(Cl)ccc(Cl)c12 CHEMBL583144 Ki 584.7 nM
NC(COc1cncc(-c2ccc3[nH]c(=O)oc3c2)c1)Cc1c[nH]c2ccccc12 CHEMBL1987679 pKi 630.96 nM
NCCCOc1cc2c(c(-c3ccc(Nc4nc5ccc(Cl)cc5o4)cc3)c1)CNC2=O CHEMBL2002479 pKi 630.96 nM
O=C1NCCc2[nH]c(-c3ccncc3)cc21 CHEMBL225519 pKi 630.96 nM
CCC(=O)Nc1ccc(C(=O)N2CCNCC2)c(O)c1 CHEMBL1988141 pKi 630.96 nM
COc1cc(OC)cc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 CHEMBL2002613 pKi 630.96 nM
Oc1cc(O)cc(C=Cc2ccc(O)c(O)c2)c1 CHEMBL1972346 pKi 630.96 nM
CCNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)n2)s1 CHEMBL1983715 pKi 630.96 nM
CN1CCC(NC(=O)c2cc3c(-c4ccccc4)n[nH]c3s2)CC1 CHEMBL1987007 pKi 630.96 nM
NC(=O)c1ccc2nc(-c3ccc([N+](=O)[O-])o3)cn2c1 CHEMBL1973359 pKi 630.96 nM
CC(N)C1CCC(C(=O)Nc2ccncc2)CC1 CHEMBL1994526 pKi 630.96 nM
Cc1cccc(Cl)c1-c1cccc2c(CCCOc3cccc4ccccc34)c(C(=O)NCCOCCOCCN)[nH]c12 CHEMBL2002682 pKi 794.33 nM
Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 CHEMBL1964687 pKi 794.33 nM
Cc1c[nH]c2nccc(Oc3c(F)cc(Nc4cc(Cl)nc(N)n4)cc3F)c12 CHEMBL1971943 pKi 794.33 nM
CC(CCC(=O)O)(c1ccc(O)c(N)c1)c1ccc(O)c(N)c1 CHEMBL1975923 pKi 794.33 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCCC4=O)c3)n2)c1 CHEMBL1991429 pKi 794.33 nM
Cc1ccccc1NC(=O)Nc1ccc2c(c1)CCc1sc3ncnc(N)c3c1-2 CHEMBL1982135 pKi 794.33 nM
CCCC(=O)Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 CHEMBL1998470 pKi 794.33 nM
Nc1ncnc2sc3c(c12)-c1ccc(NC(=O)Nc2ccccc2)cc1CC3 CHEMBL1994693 pKi 794.33 nM
CS(=O)(=O)NCCOc1cncc(-c2ccc3cnccc3c2)c1 CHEMBL1964804 pKi 794.33 nM
CN(c1ncccc1CNc1nc(Nc2ccc3c(c2)CC(=O)N3)ncc1C(F)(F)F)S(C)(=O)=O CHEMBL1084546 pKi 794.33 nM
NCCCOc1cncc(C=Cc2ccncc2)c1 CHEMBL1972258 pKi 794.33 nM
CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCOCC5CC5)c4)n[nH]c2-3)CC1 CHEMBL2002446 pKi 794.33 nM
Cc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)n[nH]c12 CHEMBL1973937 pKi 794.33 nM
O=C(Nc1cccc(C(F)(F)F)n1)Nc1ccnc2c(C(F)(F)F)cccc12 CHEMBL1980142 pKi 794.33 nM
CC(C)N(CCCN)C(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)c1 CHEMBL1994318 pKi 794.33 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3F)cc2OC)c1 CHEMBL1991188 pKi 794.33 nM
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL608533 Kd 960.0 nM
CCN1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccc5[nH]ncc5c4)n3)cc2)CC1 CHEMBL1967998 pKi 1000.0 nM
CCOc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1974254 pKi 1000.0 nM
NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccc(Cl)cc1Cl CHEMBL1965660 pKi 1000.0 nM
COc1cc(Nc2ncnc(N3CCCc4cc(C)ccc43)n2)cc(OC)c1OC CHEMBL1992125 pKi 1000.0 nM
NC(=O)c1cc2c(Oc3cccc(F)c3)cncc2s1 CHEMBL1964777 pKi 1000.0 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncn3)cc2)c1 CHEMBL2004872 pKi 1000.0 nM
CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CHEMBL1983111 pKi 1000.0 nM
Cc1ccc(C)c(NC(=O)c2cc(-c3ccco3)nc3ccccc23)c1 CHEMBL1984296 pKi 1000.0 nM
Oc1ccc2nc(-c3ccc(Sc4ccc(-c5nc6ccc(O)cc6[nH]5)cc4)cc3)[nH]c2c1 CHEMBL2001149 pKi 1000.0 nM
O=C1Nc2cc(CCOc3ccc(N4CCOCC4)cc3)ccc2Nc2cc(-c3cn(Cc4cc(F)c(F)c(F)c4)c4cnccc34)ccc21 CHEMBL2001923 pKi 1000.0 nM
O=C(O)c1ccccc1Nc1ncnc(Nc2ccc3cn[nH]c3c2)n1 CHEMBL1986666 pKi 1000.0 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL514499 pKi 1000.0 nM
CNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)s1 CHEMBL1999484 pKi 1000.0 nM
Cc1cc2cc(-c3csc4c(-c5cccc(S(C)(=O)=O)c5)cnc(N)c34)ccc2[nH]1 CHEMBL1997822 pKi 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM