CN(CCN)Cc1ccccc1Sc1ccccc1Cl CHEMBL4094513 IC50 1.2 nM
CNCCN(C)Cc1n[nH]cc1-c1ccc(Oc2cccc(C(=O)N(C)C)c2)cc1 CHEMBL3589043 IC50 2.0 nM
CN(CCN)Cc1cn[nH]c1-c1ccc(Oc2ccccc2)cc1 CHEMBL3589029 IC50 2.0 nM
CNCCN(C)Cc1c[nH]nc1-c1ccc(Oc2cccc(C(=O)N(C)C)c2)cc1 CHEMBL3589042 IC50 3.0 nM
CC(C)Oc1ccc(-c2c[nH]cc2CN(C)CCN)cc1 CHEMBL3901808 IC50 4.0 nM
CNCCN(C)Cc1n[nH]cc1-c1ccc(Oc2ccccc2C(=O)NC)cc1 CHEMBL3590417 IC50 5.0 nM
CC(C)Oc1ccc(-c2[nH]ncc2CN(C)CCN)cc1 CHEMBL3589026 IC50 7.0 nM
CNCCN(C)Cc1c[nH]nc1-c1ccc(O[C@H]2C[C@H](OCCC3CCOCC3)C2)cc1 CHEMBL3589039 IC50 7.1 nM
CC(C)Oc1ccc(-c2[nH]ncc2CN(C)CCN)cc1Cl CHEMBL3589030 IC50 8.0 nM
CNCCN(C)Cc1cn[nH]c1-c1ccc(OC(C)C)c(Cl)c1 CHEMBL3589031 IC50 10.0 nM
CC(C)Cc1ccc(-c2[nH]ncc2CN(C)CCN)cc1 CHEMBL3589028 IC50 10.0 nM
CNCCN(C)Cc1cn[nH]c1-c1ccc(OC(C)C)cc1 CHEMBL3589027 IC50 11.0 nM
CN(CCN)Cc1cn[nH]c1-c1ccc(F)cc1 CHEMBL3589912 IC50 11.0 nM
CN(CCN)Cc1c[nH]nc1-c1ccc(OCCCN2CCOCC2)cc1 CHEMBL3589040 IC50 13.0 nM
C=CC(=O)Nc1cccc(-c2c[nH]cc2CN(C)CCN)c1 CHEMBL4463793 pIC50 15.85 nM
CN(CCN)Cc1c[nH]nc1-c1ccc(N2CCN(C(=O)Cc3ccccc3)CC2)cc1 CHEMBL3589041 IC50 20.0 nM
CNCCN(C)Cc1cnn(C)c1-c1ccc(OC(C)C)c(Cl)c1 CHEMBL3589032 IC50 23.0 nM
CCC(CO)Oc1ccc(-c2[nH]ncc2CN(C)CCNC)cc1 CHEMBL3589033 IC50 25.0 nM
CCOc1ccc(-c2[nH]ncc2CN(C)CCNC)cc1 CHEMBL3589913 IC50 25.0 nM
CNCCN1CCC(OCc2ccc(-n3nc(C)cc3C)cc2)CC1 CHEMBL3956007 IC50 25.0 nM
CNCCN1CCC(OCc2ccccc2Br)CC1 CHEMBL3906680 IC50 25.0 nM
CCC(=O)Nc1cccc(-c2c[nH]cc2CN(C)CCN)c1 CHEMBL4544587 pIC50 25.12 nM
CNCCN1CCC(OCc2ccc(Oc3cccc(Cl)c3Cl)cc2)CC1 CHEMBL3984626 IC50 26.0 nM
CNCCN1CCC(OCc2ccc(-c3ccccc3)cc2)CC1 CHEMBL3957029 IC50 27.0 nM
CNCCN1CCC(OCc2ccc(C3CCCCC3)cc2)CC1 CHEMBL3939593 IC50 28.0 nM
CNCCN1CCC(OCc2cccc(-c3ccccc3)c2)CC1 CHEMBL3970878 IC50 30.0 nM
CNCCN1CCC(OCc2ccccc2Cl)CC1 CHEMBL3952337 IC50 30.0 nM
CNCCN(C)Cc1ccnc(-c2ccc(NS(=O)(=O)C3CC3)cc2)c1 CHEMBL5420795 IC50 30.0 nM
CNCCN(C)Cc1cn[nH]c1-c1ccc(OC(CO)C(C)C)cc1 CHEMBL3589034 IC50 32.0 nM
CNCCN1CCC(OCc2ccccc2)CC1 CHEMBL3961701 IC50 34.0 nM
CNCCN1CCC(OCc2ccc(F)cc2)CC1 CHEMBL3924657 IC50 38.0 nM
CNCCN1CCC(OCc2ccc(Cl)cc2)CC1 CHEMBL3943629 IC50 40.0 nM
CNCCN1CCC(OCc2ccc(Br)cc2)CC1 CHEMBL3938938 IC50 44.0 nM
CNCCN1CCC(OCc2ccc(OC(F)(F)F)cc2)CC1 CHEMBL3929454 IC50 46.0 nM
CNCCN1CCC(OCc2ccccc2F)CC1 CHEMBL3928539 IC50 47.0 nM
CNCCN1CCC(OCc2ccc(OCC(F)(F)F)cc2)CC1 CHEMBL3930600 IC50 48.0 nM
CNCCN1CCC(OCc2ccccc2-c2ccccc2)CC1 CHEMBL3948358 IC50 48.0 nM
CNCCN1CCC(OCc2cccc(Br)c2)CC1 CHEMBL3983725 IC50 53.0 nM
CNCCN1CCC(OCc2cccc(F)c2)CC1 CHEMBL3955728 IC50 56.0 nM
CNCCN1CCC(CCc2ccccc2)CC1 CHEMBL3892699 IC50 56.0 nM
CNCCN1CCC(OCc2ccccc2C(F)(F)F)CC1 CHEMBL3925764 IC50 64.0 nM
CCC(C)(C)c1ccc(COC2CCN(CCNC)CC2)cc1 CHEMBL3911620 IC50 67.0 nM
CNCCN1CC(NCc2cccc(-c3ccccc3)c2)C1 CHEMBL4068717 IC50 67.0 nM
CNCCN1CCC(Cc2ccccc2)C1 CHEMBL3969797 IC50 70.0 nM
CNCCN1CCC(OCc2ccc(CC(C)C)cc2)CC1 CHEMBL3902609 IC50 72.0 nM
Cc1cc(C)cc([C@@H]2c3cc(C)ccc3NC(=O)CN2C(=O)c2ccc(Br)s2)c1 CHEMBL5070897 IC50 77.0 nM
Cc1cc(C)cc([C@@H]2c3cc(C)ccc3NC(=O)CN2C(=O)c2ccc(Br)o2)c1 CHEMBL5093469 IC50 77.0 nM
CNCCN1CCC(OCc2cccc(Cl)c2)CC1 CHEMBL3915667 IC50 78.0 nM
CNCCN1CCC(Oc2ccccc2)CC1 CHEMBL3889478 IC50 90.0 nM
CC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@H](C[C@H](CC[C@H](N)C(=O)O)CNC(=N)N)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21 CHEMBL5197421 IC50 90.0 nM
CNCCN1CCC(COc2ccccc2)CC1 CHEMBL3981736 IC50 92.0 nM
CNCCN1CC(NCc2cccc(F)c2)C1 CHEMBL4071435 IC50 101.0 nM
CNCCN1CCC(OC(=O)c2ccccc2)CC1 CHEMBL3910681 IC50 107.0 nM
CNCCN1CCC(CNc2ccccc2)CC1 CHEMBL3964631 IC50 116.0 nM
CNCCN1CCC(OCc2cccc(C(F)(F)F)c2)CC1 CHEMBL3960002 IC50 117.0 nM
CNCCN1CCC(NCc2cccc(-c3ccccc3)c2)CC1 CHEMBL4096482 IC50 120.0 nM
CNCCN1CCC(NC(=O)c2ccccc2)CC1 CHEMBL3961070 IC50 129.0 nM
CNCCN1CC(NCc2cccc(Cl)c2)C1 CHEMBL4098465 IC50 133.0 nM
CNCCN1CCC(OCc2ccc(C(F)(F)F)cc2)CC1 CHEMBL3890919 IC50 144.0 nM
CNCCN1CCC(Cc2ccccc2)CC1 CHEMBL3936550 IC50 170.0 nM
CNCCN1CCC(Nc2ccccc2)CC1 CHEMBL3924501 IC50 186.0 nM
CNCCN(C)Cc1cncc(-c2ccc(NS(=O)(=O)C3CC3)cc2)c1 CHEMBL5431366 IC50 192.0 nM
CNCCN(C)Cc1cncc(-c2ccc(NS(=O)(=O)C(F)(F)F)cc2)c1 CHEMBL5404410 IC50 213.0 nM
Cc1cc(C)cc(C2c3cc(C)ccc3NC(=O)CN2C(=O)c2ccc(Br)s2)c1 CHEMBL5085334 IC50 214.0 nM
NCCN1CCC(Cc2ccccc2)CC1 CHEMBL3780926 IC50 230.0 nM
CNCCN1CC(NCc2cccc(Br)c2)C1 CHEMBL4081966 IC50 249.0 nM
CNCCN(C)Cc1cncc(-c2cccc(NS(=O)(=O)C3CC3)c2)c1 CHEMBL5439264 IC50 262.0 nM
CNCCN1CCCC(Cc2ccccc2)C1 CHEMBL3925616 IC50 290.0 nM
CC(C)Oc1c(Cl)cc(-c2c[nH]nc2CN(C)CCN)cc1C(F)(F)F CHEMBL3589035 IC50 320.0 nM
CNCCN(C)Cc1cn[nH]c1-c1cc(OCCc2ccccc2)cc(C(F)(F)F)c1 CHEMBL3589036 IC50 327.0 nM
Cc1ccc2c(c1)[C@@H](c1ccc(F)cc1)N(C(=O)c1ccc(Br)o1)CC(=O)N2 CHEMBL5084397 IC50 388.0 nM
C[C@H](N)C(=O)NCc1ccc(Oc2cc(Cl)cc(Cl)c2)cc1 CHEMBL4519457 IC50 400.0 nM
CNCCN1CC(NCc2cccc(OC(F)(F)F)c2)C1 CHEMBL4089823 IC50 434.0 nM
CNCCN(C)Cc1cn[nH]c1-c1cc(OCCC2CCCCC2)cc(C(F)(F)F)c1 CHEMBL3589037 IC50 461.0 nM
CNCCN1CCC(C(O)c2ccccc2)CC1 CHEMBL3952189 IC50 469.0 nM
CNCCN1CC(NCc2cccc(C(F)(F)F)c2)C1 CHEMBL4060061 IC50 469.0 nM
CNCCN1CCC(Sc2ccccc2)CC1 CHEMBL3907621 IC50 488.0 nM
CNCCNCc1cccc(-c2nc(Nc3ccccc3)c(C)c(-c3c(C)noc3C)n2)c1 CHEMBL5266562 IC50 490.0 nM
CNCCN1CCC(COC(=O)c2ccccc2)CC1 CHEMBL3972730 IC50 515.0 nM
CNCCN(C)Cc1cncc(-c2cccc(NS(=O)(=O)C(F)(F)F)c2)c1 CHEMBL5397831 IC50 684.0 nM
C[C@H](N)C(=O)NCc1ccc(Oc2cccc(Cl)c2Cl)cc1 CHEMBL4469882 IC50 700.0 nM
C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3220560 Km 751.0 nM
Cc1ccc2c(c1)C(c1ccc(F)cc1)N(C(=O)c1ccc(Br)o1)CC(=O)N2 CHEMBL5089738 IC50 755.0 nM
C[C@H](N)C(=O)NCc1ccc(Oc2cccc3ccccc23)cc1 CHEMBL4458225 IC50 800.0 nM
CCNCCN1CCC(Cc2ccccc2)CC1 CHEMBL3986367 IC50 830.0 nM
N=C(N)NCCC[C@H](NC(=O)CN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=[N+]1CCCC1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3220557 Km 838.0 nM