COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(Cl)cc3)c2=O)cc1 CHEMBL551383 IC50 19.0 nM
COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(OC)cc3)c2=O)cc1 CHEMBL562111 IC50 21.0 nM
CCc1ccc(Cn2c(=O)nc(NCCNC(=N)N)n(Cc3ccc(OC)cc3)c2=O)cc1 CHEMBL457515 Ki 22.0 nM
COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(Cl)c(Cl)c3)c2=O)cc1 CHEMBL550780 IC50 22.0 nM
COc1ccc(Cn2c(=O)nc(NCCNC(=N)N)n(Cc3ccc(O)cc3)c2=O)cc1 CHEMBL551583 IC50 27.0 nM
COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 CHEMBL550577 IC50 33.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(C#N)c2ccc(Cl)cc2)CC1 CHEMBL3889670 IC50 40.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(=C(C#N)c2ccc(Cl)cc2)CC1 CHEMBL3977908 IC50 40.0 nM
N=C(N)NCCNc1nc(=O)n(Cc2ccc(Cl)c(Cl)c2)c(=O)n1Cc1ccc(OC(F)F)cc1 CHEMBL549558 IC50 47.0 nM
CCc1n[nH]c(CC)c1S(=O)(=O)N1CCC(=C(C#N)c2ccc(Cl)cc2)CC1 CHEMBL3917980 IC50 50.0 nM
COc1cc(Cl)ccc1CC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3956849 IC50 50.0 nM
COc1ccc(Cn2c(=O)nc(NCCNC(=N)N)n(Cc3ccc(OC)nc3)c2=O)cc1 CHEMBL559719 IC50 51.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2cnc3ccccc3c2)CC1 CHEMBL3898347 IC50 60.0 nM
COC(c1ccc(Cl)cc1)C1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3893095 IC50 60.0 nM
COc1cc(Cl)ccc1CC1CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3947348 IC50 70.0 nM
COC(c1ccc(Cl)cc1)C1CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3986275 IC50 80.0 nM
COc1cc(Cl)ccc1CC1(F)CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3898520 IC50 140.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(C#N)c2ccc(OC(F)(F)F)cc2)CC1 CHEMBL3953005 IC50 150.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2ccc(Cl)cc2)CC1 CHEMBL3919323 IC50 160.0 nM
COc1cc(Cl)ccc1OC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3897887 IC50 170.0 nM
COc1cc(Cl)ccc1CC1(F)CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3958623 IC50 170.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(C#N)c2ccc(Cl)cc2F)CC1 CHEMBL3928918 IC50 180.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2ccc(Cl)c(F)c2)CC1 CHEMBL3933683 IC50 190.0 nM
COc1cc(Cl)ccc1OC1CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3972544 IC50 200.0 nM
COc1cc(Cl)ccc1CC1(O)CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3954927 IC50 200.0 nM
Cc1c(S(=O)(=O)N2CCC(=C(C#N)c3ccc(Cl)cc3)CC2)c(C(F)(F)F)nn1C CHEMBL3915207 IC50 210.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2C(F)(F)F)CC1 CHEMBL3984251 IC50 210.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2C(F)(F)F)CC1 CHEMBL3910847 IC50 210.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc3ccccc3c2)CC1 CHEMBL3975166 IC50 220.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2C#N)CC1 CHEMBL3976696 IC50 240.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2ccc(Cl)cc2Cl)CC1 CHEMBL3973243 IC50 260.0 nM
CNc1cc(C(=O)N2CCCC(F)(c3ncc(Cl)cc3C)C2)ccn1 CHEMBL3622090 IC50 290.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2C#N)CC1 CHEMBL3952785 IC50 310.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C(F)c2ccc(Cl)cc2)CC1 CHEMBL3982097 IC50 310.0 nM
COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(C#N)cc3)c2=O)cc1 CHEMBL562508 IC50 318.0 nM
CC(C)n1c(C2CCCN(C(=O)c3ccnc(N(C)C)c3)C2)nc2ccccc21 CHEMBL3622086 IC50 320.0 nM
CCc1nn(C)c(CC)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2Cl)CC1 CHEMBL3972452 IC50 320.0 nM
CCn1cc(C(=O)N2CCCC(c3cc4ccccc4n3C(C)C)C2)cn1 CHEMBL3622087 IC50 330.0 nM
COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccccc3)c2=O)cc1 CHEMBL563405 IC50 336.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C(c2ccc(Cl)cc2)C(F)F)CC1 CHEMBL3949632 IC50 340.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2ccc(Cl)cc2F)CC1 CHEMBL3936424 IC50 400.0 nM
COc1cc(Cl)ccc1CC1(O)CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3889563 IC50 410.0 nM
CCc1ccc(Cn2c(=O)nc(NCCN)n(Cc3ccc(OC)cc3)c2=O)cc1 CHEMBL514895 Ki 440.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2ccc3ccccc3c2)CC1 CHEMBL3944037 IC50 440.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)c(F)c2)CC1 CHEMBL3973527 IC50 440.0 nM
COc1ccc(CCn2c(=O)nc(NCCNC(=N)N)n(Cc3ccc(OC)cc3)c2=O)cc1 CHEMBL560171 IC50 461.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CC/C(=C(\C#N)c2ccc(Cl)cc2)C(C)C1 CHEMBL3903512 IC50 470.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Br)cc2F)CC1 CHEMBL3919321 IC50 470.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C(C)c2ccc(Cl)cc2)CC1 CHEMBL3937917 IC50 470.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2F)CC1 CHEMBL3907450 IC50 510.0 nM
CCCOc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(Cl)c(Cl)c3)c2=O)cc1 CHEMBL557700 IC50 515.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2ccc(Cl)c(Cl)c2)CC1 CHEMBL3981959 IC50 520.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)cc2)CC1 CHEMBL3924982 IC50 520.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)cc2)CC1 CHEMBL3895489 IC50 520.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2)CC1 CHEMBL3973065 IC50 530.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(=Cc2ccc(Cl)cc2F)CC1 CHEMBL3941566 IC50 550.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=Cc2ccc(Cl)cc2F)CC1 CHEMBL3893804 IC50 600.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C(C#N)c2ccc(Cl)cc2)CC1 CHEMBL3903989 IC50 610.0 nM
CCOC(=O)C1(Cc2ccc(Br)cc2)CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3973051 IC50 640.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(F)(Cc2ccc(Cl)cc2F)CC1 CHEMBL3951596 IC50 670.0 nM
CCOC(=O)C1(Cc2ccc(Br)cc2)CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3934571 IC50 680.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(C(O)c2ccc(Cl)cc2)CC1 CHEMBL3913003 IC50 710.0 nM
COc1cc(Cl)cnc1OC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3905662 IC50 720.0 nM
CCOC(c1ccc(Cl)cc1)C1CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 CHEMBL3906648 IC50 720.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)cc2F)CC1 CHEMBL3979518 IC50 730.0 nM
CC(=C1CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1)c1ccc(Cl)cc1 CHEMBL3938854 IC50 760.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=Cc2ccc(Cl)cc2)CC1 CHEMBL3980270 IC50 760.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)c(F)c2)CC1 CHEMBL3924529 IC50 780.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2Cl)CC1 CHEMBL3946318 IC50 790.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(F)(Cc2ccc(Cl)cc2F)CC1 CHEMBL3891242 IC50 810.0 nM
Cc1ccc(OC2CCN(S(=O)(=O)c3c(C)nn(C)c3C)CC2)cc1 CHEMBL3955678 IC50 820.0 nM
Cc1ccc(OC2CCN(S(=O)(=O)c3c(C)nn(C)c3Cl)CC2)cc1 CHEMBL3912835 IC50 860.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C#N)(Cc2ccc(Cl)cc2)CC1 CHEMBL3943549 IC50 890.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(N(C)c2ccc(Cl)cc2)CC1 CHEMBL3963619 IC50 900.0 nM
COCC1(Cc2ccc(Cl)cc2)CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 CHEMBL3929119 IC50 900.0 nM
CCn1c(C2CCCN(C(=O)c3cn(C)nc3N)C2)cc2cc(Cl)ccc21 CHEMBL3622089 IC50 910.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C#N)(Cc2ccc(Cl)cc2Cl)CC1 CHEMBL3981069 IC50 940.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Cc2ccc(Cl)c(Cl)c2)CC1 CHEMBL3964334 IC50 950.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(C(=O)c2ccc(Cl)cc2)CC1 CHEMBL3978781 IC50 1000.0 nM
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)c(Cl)c2)CC1 CHEMBL3932513 IC50 1000.0 nM
Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2c(F)cc(Cl)cc2F)CC1 CHEMBL3912045 IC50 1000.0 nM