O=C1O[C@H]2CCC[C@@H]2[C@@H]1Sc1ccccc1 CHEMBL100989 IC50 0.02 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL453539 Ki 0.03 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)B(O)O CHEMBL290376 Ki 0.045 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)B(O)O CHEMBL607008 Ki 0.045 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3cccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)c3)o2)cc1 CHEMBL3642936 Ki 0.054 nM
N=C(N)c1ccc2cc(OC(=O)c3ccc(CN4CCC[C@@H]4C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)o3)ccc2c1 CHEMBL3944540 Ki 0.08 nM
Cc1cc(-c2ccccc2S(N)(=O)=O)ccc1C(=O)N[C@@H](CCCN=C(N)N)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL418071 Ki 0.11 nM
O=C1O[C@H]2CCC[C@@H]2[C@H]1Sc1ccccc1 CHEMBL99622 IC50 0.12 nM
CC(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642924 Ki 0.12 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3642903 Ki 0.15 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3951207 IC50 0.17 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642902 Ki 0.18 nM
CC(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3642965 Ki 0.18 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)N[C@H](Cc4ccc(OCC(=O)O)cc4)C(=O)O)ccc3c2)cc1 CHEMBL4109828 IC50 0.18 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(O)cc(C(=O)O)c1 CHEMBL3672886 Ki 0.18 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642941 Ki 0.19 nM
CC(C(=O)N(CC(=O)O)Cc1cccc(C(=O)O)c1)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1Cl CHEMBL3917451 IC50 0.19 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3914629 Ki 0.19 nM
CC(Cc1coc(C(=O)Oc2ccc(C(=N)N)cc2)c1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642932 Ki 0.2 nM
CC(Cc1ncc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642982 Ki 0.2 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccc(Cl)cc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3897484 IC50 0.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642957 Ki 0.21 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(C(=O)O)c(C(=O)O)c1 CHEMBL3672880 Ki 0.21 nM
N=C(N)Nc1ccc(C(=O)Oc2cc(F)c(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(F)c2)cc1 CHEMBL3985298 IC50 0.21 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)N(CC(=O)O)Cc4csc(C(=O)O)c4)ccc3c2)cc1 CHEMBL3957994 IC50 0.21 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3921980 Ki 0.21 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2[N+](=O)[O-])s1)C(=O)O CHEMBL3642895 Ki 0.22 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCP(=O)(O)O CHEMBL3642958 Ki 0.22 nM
CC(C)(Oc1ccc(C[C@H](NC(=O)CCc2ccc(OC(=O)c3ccc(NC(=N)N)cc3)cc2Cl)C(=O)O)cc1)C(=O)O CHEMBL3979741 IC50 0.22 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc3)o2)cc1 CHEMBL3642933 Ki 0.23 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccc(F)cc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3971081 IC50 0.23 nM
COc1ccc(C[C@H](NC(=O)Cc2ccc(OC(=O)c3ccc(NC(=N)N)cc3)cc2Cl)C(=O)O)cc1 CHEMBL3947460 IC50 0.23 nM
CN(C(=O)N(CC(=O)O)Cc1cccc(C(=O)O)c1)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1Cl CHEMBL3980104 IC50 0.23 nM
Cc1nc(N)ccc1CNC(=O)Cn1c(C)cc2c(c1=O)NC(=O)[C@](C)(CC(C)C)C2 CHEMBL11181 Ki 0.24 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)NC(CC(=O)O)c4ccccc4)ccc3c2)cc1 CHEMBL3972244 IC50 0.24 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)N(CC(=O)O)Cc4ccc(CC(=O)O)cc4)ccc3c2)cc1 CHEMBL3893474 IC50 0.24 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)o2)cc1 CHEMBL3951001 Ki 0.24 nM
N=C(N)c1ccc(OC(=O)c2cc3c(s2)CN(C(=O)N[C@@H](CC(=O)O)C(=O)O)CC3)c(F)c1 CHEMBL3915122 Ki 0.24 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3900248 Ki 0.25 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)NC(C(=O)O)c4ccccc4)ccc3c2)cc1 CHEMBL3947949 IC50 0.26 nM
N=C(N)Nc1ccc(C(=O)Oc2cc(Cl)c(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3939171 IC50 0.26 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3cccc(F)c3)C(=O)O)c(Cl)c2)cc1 CHEMBL3969953 IC50 0.26 nM
Cc1nc(N)ccc1CNC(=O)Cn1c(C)cc2c(c1=O)NC(=O)C(CC(C)C)(CC(C)C)C2 CHEMBL10346 Ki 0.27 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc3)s2)c(F)c1 CHEMBL3642973 Ki 0.27 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)N(CC(=O)O)Cc4cccc(C(=O)O)c4)ccc3c2)cc1 CHEMBL3941889 IC50 0.27 nM
COc1ccc(-n2c(=O)n3n(c2=O)C(C(=O)NC(CCCCN)C(=O)C(=O)NCCc2ccc(C(N)=O)cc2)C=CC3CC(C)C)cc1 CHEMBL73970 Ki 0.28 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)Nc4ccc(CC(=O)O)cc4)ccc3c2)cc1 CHEMBL3977211 IC50 0.29 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(C(F)(F)F)c2)cc1 CHEMBL3933667 IC50 0.29 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(Cl)c2Cl)cc1 CHEMBL3961130 IC50 0.29 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3ccccc3)c(Cl)c2)cc1 CHEMBL3909962 IC50 0.29 nM
C[C@H](C(=O)O)N(Cc1csc(C(=O)O)c1)C(=O)c1ccc2cc(OC(=O)c3ccc(NC(=N)N)cc3)ccc2n1 CHEMBL4106875 IC50 0.29 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3890156 Ki 0.29 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)NCP(=O)(O)O)cc3)o2)cc1 CHEMBL3642935 Ki 0.3 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)NCc3ccccc3C(=O)O)c(Cl)c2)cc1 CHEMBL3925221 IC50 0.3 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccccc3F)C(=O)O)c(Cl)c2)cc1 CHEMBL3940399 IC50 0.31 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccc(C(F)(F)F)cc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3977663 IC50 0.31 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)c3cccc(CC(=O)O)c3)c(Cl)c2)cc1 CHEMBL3922459 IC50 0.32 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)c(F)c2)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642946 Ki 0.33 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N[C@H](CC(=O)O)c3ccccc3)c(Cl)c2)cc1 CHEMBL4113549 IC50 0.34 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCN(CC(=O)O)C(=O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3929693 IC50 0.35 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(C3CC3)c2)cc1 CHEMBL3953763 IC50 0.36 nM
CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3642964 Ki 0.37 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3cc(C(=O)O)cc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3890692 IC50 0.37 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642886 Ki 0.38 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCCCC(=O)NC(Cc3ccccc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3963997 IC50 0.38 nM
C=CCN(CC(=O)O)C(=O)[C@@H]1CSCN1Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3897433 Ki 0.38 nM
CC(C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3982871 Ki 0.38 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642904 Ki 0.39 nM
C/C(=C\c1nc(C(=O)Oc2ccc(C(=N)N)cc2)cs1)C(=O)N(CCCO)CC(=O)O CHEMBL3642940 Ki 0.39 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CCC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642977 Ki 0.4 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCN(CC(=O)O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3967403 IC50 0.4 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(Cc3cccc(C(=O)O)c3)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3960457 IC50 0.4 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCC(=O)O CHEMBL3667881 Ki 0.42 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N(CCC(=O)O)[C@@H](Cc3ccccc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3912722 IC50 0.42 nM
CN(C(=O)CN(CC(=O)O)Cc1cccc(C(=O)O)c1)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1Cl CHEMBL3955210 IC50 0.42 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N(CCC(=O)O)CC(=O)O)s2)c(F)c1 CHEMBL4108738 Ki 0.42 nM
CC(C)CCn1c(=O)n2n(c1=O)C(C(=O)NC(CCCCN)C(=O)C(=O)NCCc1ccc(C(N)=O)cc1)C=CC2CC(C)C CHEMBL75269 Ki 0.43 nM
CCC[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642944 Ki 0.43 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(-c3ccccc3)c2)cc1 CHEMBL3962586 IC50 0.43 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3962513 IC50 0.43 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3csc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3985101 IC50 0.43 nM
C=CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)O)C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3943096 Ki 0.43 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCC(=O)O CHEMBL3642857 Ki 0.44 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)co1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642931 Ki 0.44 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)NCP(=O)(O)O)s2)c(F)c1 CHEMBL3642962 Ki 0.44 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N(CCc3ccccc3)CC(=O)O)c(Cl)c2)cc1 CHEMBL3893507 IC50 0.44 nM
CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3912993 Ki 0.44 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3ccccc3C(=O)O)c(Cl)c2)cc1 CHEMBL3940716 IC50 0.45 nM
CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3960291 Ki 0.45 nM
CC1=CCN(C(=O)[C@H](Cc2ccc(C(=N)N)cc2)NS(=O)(=O)c2ccc3c(c2)CN(C)CC3)[C@@H](C(=O)O)C1 CHEMBL430526 Ki 0.46 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCCC(=O)N(CC(=O)O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3949492 IC50 0.46 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642912 Ki 0.47 nM
CC(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1 CHEMBL3642966 Ki 0.47 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](C(=O)O)C(C)O CHEMBL3642866 Ki 0.48 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642948 Ki 0.48 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)NCP(=O)(O)O CHEMBL3642959 Ki 0.49 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)O)c1 CHEMBL3672872 Ki 0.49 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3cccc(CC(=O)O)c3)c(Cl)c2)cc1 CHEMBL3941734 IC50 0.49 nM
CC(C)=CC(=O)C[C@@H]1C(=O)O[C@H]2CCC[C@@H]21 CHEMBL101041 IC50 0.5 nM
Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)sc1CCC(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3639418 Ki 0.5 nM
C=CCN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667883 Ki 0.5 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N(CC(=O)O)[C@@H](Cc3ccccc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3940894 IC50 0.5 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)cs1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642968 Ki 0.51 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(Cc3ccccc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3964583 IC50 0.51 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642856 Ki 0.52 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642909 Ki 0.52 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL4110371 Ki 0.52 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)SC(CC(=O)O)C(=O)O CHEMBL3642938 Ki 0.53 nM
CN(C(=O)N(CC(=O)O)Cc1csc(C(=O)O)c1)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1Cl CHEMBL3916887 IC50 0.54 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3891228 Ki 0.54 nM
N=C(N)c1ccc(OC(=O)c2cc3c(s2)CN(CC(=O)O)CC3)c(F)c1 CHEMBL3929534 Ki 0.56 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642960 Ki 0.57 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CCC(=O)O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3923332 IC50 0.57 nM
O=C1O[C@H]2CCC[C@@H]2[C@@H]1Cc1ccccc1 CHEMBL101030 IC50 0.6 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642979 Ki 0.6 nM
CN(CC(=O)N[C@@H](CCCN=C(N)N)B(O)O)C(=O)CCc1ccccc1 CHEMBL95940 Ki 0.61 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)N[C@@H](CC(=O)O)C(=O)O)CCC3)s2)c(F)c1 CHEMBL3667879 Ki 0.61 nM
CCN(CC)S(=O)(=O)c1ccccc1-c1ccc(C(=O)N[C@@H](CCCN=C(N)N)B2O[C@@H]3CC4CC(C4(C)C)[C@]3(C)O2)c(C)c1 CHEMBL290212 Ki 0.62 nM
CCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642882 Ki 0.62 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642910 Ki 0.62 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)NCC(=O)O)cc3)o2)cc1 CHEMBL3642934 Ki 0.62 nM
COC(=O)NS(=O)(=O)c1ccccc1-c1ccc(C(=O)N[C@@H](CCCN=C(N)N)B2O[C@@H]3CC4CC(C4(C)C)[C@]3(C)O2)c(C)c1 CHEMBL287964 Ki 0.64 nM
C=CCN(CC(=O)O)C(=O)[C@@H]1CCCN1Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3976398 Ki 0.64 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642947 Ki 0.66 nM
CC(C)(Oc1ccc(C[C@@H](NC(=O)Cc2ccc(OC(=O)c3ccc(NC(=N)N)cc3)cc2Cl)C(=O)O)cc1)C(=O)O CHEMBL4113470 IC50 0.66 nM
CC(C)[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3907536 Ki 0.68 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642858 Ki 0.69 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CCC[C@@H](C(=O)O)C1 CHEMBL4113880 Ki 0.69 nM
CC(C)N(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3951843 Ki 0.69 nM
Cc1cc(-c2ccccc2S(=O)(=O)NC(C)(C)C)ccc1C(=O)N[C@@H](CCCN=C(N)N)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL40854 Ki 0.7 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc3)s2)cc1 CHEMBL3642972 Ki 0.7 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL3667910 Ki 0.7 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3965069 Ki 0.7 nM
CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3898510 Ki 0.7 nM
C=CCN(C(=O)CN1CCc2cc(C(=O)Oc3ccc(C(=N)N)cc3F)sc2C1)[C@@H](CCC(=O)O)C(=O)O CHEMBL3957106 Ki 0.71 nM
CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642923 Ki 0.72 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CCc3cccc(C(=O)O)c3)CC(=O)O)c(Cl)c2)cc1 CHEMBL3926430 IC50 0.73 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642879 Ki 0.75 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3667882 Ki 0.75 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1nnn[nH]1 CHEMBL3672877 Ki 0.75 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)Nc3ccc(CC(=O)O)cc3)c(Cl)c2)cc1 CHEMBL3926197 IC50 0.76 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(-c3ccccc3)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4172393 Ki 0.76 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)o1)C(=O)O CHEMBL3642884 Ki 0.79 nM
N=C(N)c1ccc(OC(=O)c2csc(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)c2)c(F)c1 CHEMBL3642970 Ki 0.79 nM
N=C(N)NCCC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)N[C@H](CCCNC(=N)N)C(=O)c1nccs1 CHEMBL352039 IC50 0.8 nM
CC(C)C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3969696 Ki 0.81 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3667897 Ki 0.82 nM
N=C(N)c1ccc(OC(=O)c2ccc(Cn3cccc3C(=O)O)s2)c(F)c1 CHEMBL3897108 Ki 0.82 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)c(F)c2)s1)C(=O)O CHEMBL3642906 Ki 0.83 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642952 Ki 0.84 nM
CC(C)N(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3967865 Ki 0.84 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1 CHEMBL3642889 Ki 0.86 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3920627 Ki 0.87 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4164510 Ki 0.87 nM
CN(C(=O)Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1Cl)[C@@H](Cc1ccccc1)C(=O)O CHEMBL3985783 IC50 0.88 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccc(OCC(=O)O)cc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3931837 IC50 0.88 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642907 Ki 0.89 nM
CC(C)C[C@@H](C(=O)N[C@H](CCC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL4108694 Ki 0.89 nM
C=CCN(C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)[C@@H](CC(=O)O)C(=O)O CHEMBL3642978 Ki 0.9 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)NCc3cccc(C(=O)O)c3)c(Cl)c2)cc1 CHEMBL3961505 IC50 0.9 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1C[C@H](O)C[C@H]1C(=O)O CHEMBL4109414 Ki 0.9 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3642901 Ki 0.91 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3ccc(C(=O)O)cc3)C(=O)O)c(Cl)c2)cc1 CHEMBL3951938 IC50 0.91 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)co1)C(=O)O CHEMBL3642928 Ki 0.92 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(O)c(C(=O)O)c1 CHEMBL3672860 Ki 0.92 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](Cc3c[nH]cn3)C(=O)O)c(Cl)c2)cc1 CHEMBL3923483 IC50 0.92 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCCC[C@H]3C(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3924838 Ki 0.92 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CCC(=O)O)C(=O)O CHEMBL3642878 Ki 0.95 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(C)(C)C(=O)O CHEMBL3667884 Ki 0.95 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1C[C@H]1C(=O)O CHEMBL3672874 Ki 0.96 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)c1ccc(O)cc1 CHEMBL3903777 Ki 0.96 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642911 Ki 0.97 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642951 Ki 0.97 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)o2)cc1 CHEMBL3916604 Ki 0.97 nM
N=C(N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(C(=O)CCc3ccccc3)CC(=O)N21)C(=O)c1nccs1 CHEMBL324413 IC50 1.0 nM
CC(C)C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642942 Ki 1.0 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCCO)CC(=O)O CHEMBL3642862 Ki 1.01 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CC1 CHEMBL3672870 Ki 1.01 nM
COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)s2)cc(C(=O)OC)c1 CHEMBL3672873 Ki 1.02 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3667903 Ki 1.04 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642870 Ki 1.07 nM
NCCCC[C@H](NC(=O)CN(C(=O)CCc1ccccc1)C1CC1)B(O)O CHEMBL317137 Ki 1.1 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642961 Ki 1.1 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642860 Ki 1.13 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCCO)CCC(=O)O CHEMBL3642865 Ki 1.13 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C(=O)O)c1ccc(O)cc1 CHEMBL3672881 Ki 1.14 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)cc1 CHEMBL3905647 Ki 1.14 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3642867 Ki 1.16 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cccc(S(=O)(=O)O)c1 CHEMBL3893916 Ki 1.17 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1CCCC(C(=O)O)C1 CHEMBL3642918 Ki 1.2 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CO)C(=O)O)s2)c(F)c1 CHEMBL3642981 Ki 1.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCC(=O)O CHEMBL3642859 Ki 1.26 nM
CC[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CCC(=O)O)C(=O)O CHEMBL3642881 Ki 1.28 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(N)=O)C(=O)O CHEMBL3642875 Ki 1.3 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CCC(=O)O)CC(=O)O)o2)cc1 CHEMBL3642919 Ki 1.3 nM
CC(C)C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642943 Ki 1.3 nM
CCC[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642945 Ki 1.3 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3897603 Ki 1.3 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)S(=O)(=O)O CHEMBL3642887 Ki 1.33 nM
CN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667885 Ki 1.33 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC[C@H](C(=O)O)C1 CHEMBL3949541 Ki 1.33 nM
CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCC[C@@H]1C(=O)N[C@H]1CCCC(C(=N)N)C1O CHEMBL141574 IC50 1.36 nM
CCCC(CCC)C(=O)N[C@@H](CC(=O)OC)C(=O)N1CCCC1C(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL112726 IC50 1.36 nM
CC(C)(C)OC(=O)CCc1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373367 Ki 1.4 nM
C=CCN(CC(=O)O)C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642920 Ki 1.4 nM
C=CCN(CC(=O)O)C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3642954 Ki 1.4 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCC(=O)NCC(=O)O CHEMBL3672889 Ki 1.42 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCC(=O)O CHEMBL3920800 Ki 1.42 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)c1ccccc1 CHEMBL3672850 Ki 1.45 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C(=O)O)c1ccccc1 CHEMBL3672851 Ki 1.45 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)O)o2)cc1 CHEMBL3642888 Ki 1.46 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CCC1 CHEMBL3672869 Ki 1.49 nM
COC(=O)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL554140 I50 1.5 nM
COc1ccc2c(c1)CC[C@H](NS(=O)(=O)CC1CCCCC1)C(=O)N2CC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL85238 IC50 1.5 nM
CCCN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667888 Ki 1.5 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Br)s1)C(=O)O CHEMBL3642898 Ki 1.51 nM
CN[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)N[C@H]1CCCC(C(=N)N)C1O CHEMBL423543 IC50 1.52 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642861 Ki 1.53 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1C[C@@H]1C(=O)O CHEMBL3672867 Ki 1.53 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642905 Ki 1.54 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C1(C(=O)N[C@@H](CC(=O)O)C(=O)O)CCCC1 CHEMBL3971792 Ki 1.56 nM
N=C(N)c1ccc(OC(=O)c2ccc(CNC3(C(=O)N[C@@H](CC(=O)O)C(=O)O)CC3)s2)c(F)c1 CHEMBL3958604 Ki 1.57 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)O)c1 CHEMBL3672878 Ki 1.58 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CCC(=O)O)(CCC(=O)O)CCC(=O)O CHEMBL3672871 Ki 1.59 nM
CCOC(=O)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL540096 I50 1.6 nM
N#Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL151747 I50 1.6 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1 CHEMBL3642890 Ki 1.6 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)cs1)C(=O)O CHEMBL3642967 Ki 1.6 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCc1nnn[nH]1 CHEMBL3672876 Ki 1.6 nM
CCCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642885 Ki 1.65 nM
CCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642880 Ki 1.67 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C)C(=O)O CHEMBL3667905 Ki 1.67 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@H]1C(=O)O CHEMBL3667886 Ki 1.69 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(N)=O)C(=O)O CHEMBL3672857 Ki 1.69 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCP(=O)(O)O CHEMBL3642921 Ki 1.7 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CC[C@@H](C(=O)O)CC1 CHEMBL3672882 Ki 1.7 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(C(=O)O)c(C(=O)O)c1 CHEMBL3975448 Ki 1.7 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)C(C)O CHEMBL3667893 Ki 1.74 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCC(=O)O CHEMBL3642869 Ki 1.76 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)O CHEMBL3642899 Ki 1.76 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642900 Ki 1.76 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N(C)CC(=O)O CHEMBL3667899 Ki 1.76 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3667889 Ki 1.78 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CO)C(=O)O CHEMBL3667890 Ki 1.78 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NCP(=O)(O)O CHEMBL3642956 Ki 1.8 nM
CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1 CHEMBL3642963 Ki 1.8 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](C(=O)O)C(C)O CHEMBL3642868 Ki 1.84 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(C(=O)O)C1 CHEMBL3672884 Ki 1.85 nM
COc1ncccc1NC(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3672864 Ki 1.87 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1C[C@H](O)C[C@@H]1C(=O)O CHEMBL3642872 Ki 1.88 nM
CSCc1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373350 Ki 1.9 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(-c3ccccc3)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4167071 Ki 1.9 nM
CC[C@H](NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667906 Ki 1.93 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3667902 Ki 1.96 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CCC(=O)O)C(=O)O CHEMBL3672856 Ki 1.96 nM
CCC(C)[C@H](CC(=O)O)NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3957967 Ki 1.97 nM
CCC(C)[C@@H](CC(=O)O)NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3672862 Ki 1.97 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CC=CC[C@H]1C(=O)O CHEMBL4113254 Ki 1.98 nM
O=C1O[C@H]2CCC[C@@H]2[C@H]1Cc1ccccc1 CHEMBL102081 IC50 2.0 nM
N=C(N)NCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(C(=O)CCc3ccccc3)CC(=O)N21)C(=O)c1nc2c(s1)CCC2 CHEMBL169291 IC50 2.0 nM
CCOC(=O)[C@]1(NS(=O)(=O)Cc2ccccc2)CCCN(CC(=O)N[C@H]2CCCN(C(=N)N)[C@@H]2O)C1=O CHEMBL85282 IC50 2.0 nM
N=C(N)NCCCC(NC(=O)CN1CCN(S(=O)(=O)c2cccc3cccnc23)CC1=O)C(=O)c1nccs1 CHEMBL355376 IC50 2.0 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(N)=O)C(=O)O CHEMBL3642874 Ki 2.0 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3642877 Ki 2.0 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642922 Ki 2.0 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC[C@@H](C(=O)O)C1 CHEMBL3667911 Ki 2.0 nM
CNC(=O)[C@@H]1C[C@H](N2CCc3c(cccc3OCCC3CC3)C2)CN1C(=O)c1ccc(CN)c(OC)c1 CHEMBL4528713 IC50 2.0 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N(CC(=O)O)CC1CC1 CHEMBL3672888 Ki 2.01 nM
CC(C)[C@H](NC(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667887 Ki 2.02 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CS(C)(=O)=O)nc4Cc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2373397 Ki 2.1 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CC1 CHEMBL3672891 Ki 2.19 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642955 Ki 2.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CC(=O)O)CC(=O)O CHEMBL3639417 Ki 2.29 nM
CC(C)(C)CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)c1nc2ccccc2o1 CHEMBL436851 IC50 2.3 nM
CCCc1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373402 Ki 2.3 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCO CHEMBL3642916 Ki 2.3 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O[C@H](CC(=O)O)C(=O)O CHEMBL3642937 Ki 2.3 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2[N+](=O)[O-])s1)C(=O)N(CCCO)CC(=O)O CHEMBL3642896 Ki 2.39 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3642876 Ki 2.4 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667896 Ki 2.49 nM
NCCCC[C@H](NC(=O)CN(CCc1ccccc1)C(=O)CCc1ccccc1)B(O)O CHEMBL99309 Ki 2.5 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCC(=O)O CHEMBL3667892 Ki 2.5 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CC[C@H](C(=O)O)CC1 CHEMBL3672890 Ki 2.57 nM
COC(=O)C[C@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCCC1C(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL112931 IC50 2.58 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4170662 Ki 2.6 nM
CC(C)(C)CC(=O)NCc1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373440 Ki 2.7 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCCC(C(=O)O)C1 CHEMBL3642950 Ki 2.7 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCC(=O)O CHEMBL3667908 Ki 2.73 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H]1COC(=O)C1 CHEMBL3667912 Ki 2.73 nM
CN(CC(=O)N[C@@H](CCCCN)B(O)O)C(=O)CCc1ccccc1 CHEMBL317682 Ki 2.8 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(C(=O)O)C1 CHEMBL3959399 Ki 2.87 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(=O)O)o2)cc1 CHEMBL3642883 Ki 2.89 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(C(=O)O)cc1 CHEMBL3667909 Ki 2.89 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1CCC[C@@H]1C(=O)O CHEMBL3642871 Ki 2.92 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C=O)CCCN=C(N)N CHEMBL417682 IC50 3.0 nM
CC(=N)N1CCC(Oc2ccc3c(nc(C)n3Cc3ccc4ccc(C(=N)N)cc4c3)c2[N+](=O)[O-])CC1 CHEMBL25351 Ki 3.0 nM
CC(=N)N1CCC(Oc2ccc3c(nc(C(C)C)n3Cc3ccc4ccc(C(=N)N)cc4c3)c2[N+](=O)[O-])CC1 CHEMBL283293 Ki 3.0 nM
CCS(=O)(=O)c1cc(-c2cc(C(=O)Nc3cccc(OC4CCCC4)c3)cc3ccc(C(=N)N)cc23)co1 CHEMBL320233 Ki 3.0 nM
CNC(=O)[C@@H]1C[C@H](N2CCc3c(cccc3OCCc3ccccc3)C2)CN1C(=O)c1ccc(CN)c(OC)c1 CHEMBL4435231 IC50 3.0 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)C1CCCCC1 CHEMBL3667913 Ki 3.04 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C(=O)O)C1CCCCC1 CHEMBL3667914 Ki 3.07 nM
CN[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL339122 Ki 3.1 nM
Cc1cc(-c2ccccc2C(F)(F)F)ccc1C(=O)N[C@@H](CCCN=C(N)N)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL41152 Ki 3.1 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)co1)C(=O)NCP(=O)(O)O CHEMBL3642929 Ki 3.1 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC(C(=O)O)CC1 CHEMBL3667904 Ki 3.1 nM
C=CCN(CCS(=O)(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667901 Ki 3.17 nM
N=C(N)c1ccc(CNC(=O)[C@H]2CCCN2C(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1 CHEMBL158939 Ki 3.2 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642976 Ki 3.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1C[C@@H](O)C[C@H]1C(=O)O CHEMBL3642873 Ki 3.25 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(=O)O)c1nnn[nH]1 CHEMBL3891548 Ki 3.27 nM
C[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)Cc1ccccc1)C(=O)NCc1ccc(C(=N)N)cc1 CHEMBL158405 Ki 3.3 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(F)nc1 CHEMBL3672868 Ki 3.3 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)[C@H](Cc1ccccc1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL4112097 Ki 3.31 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(CC(=O)O)cc1 CHEMBL3672861 Ki 3.35 nM
COc1ccc(NC(=O)C(C)(C)Cc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)s2)cn1 CHEMBL3672858 Ki 3.36 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCN(C)C CHEMBL3642915 Ki 3.4 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](Cc1nn[nH]n1)C(=O)O CHEMBL3977688 Ki 3.4 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCc2ccc(C(=O)O)cc2C1 CHEMBL3672863 Ki 3.49 nM
CCS(=O)(=O)c1cc(-c2cc(C(=O)Nc3ccccc3)cc3ccc(C(=N)N)cc23)co1 CHEMBL321319 Ki 3.5 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3cccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)c3)s2)cc1 CHEMBL3642974 Ki 3.5 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1nnn[nH]1 CHEMBL3672893 Ki 3.54 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@H]1C(=O)O CHEMBL3667895 Ki 3.57 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@@H]1C(=O)O CHEMBL3667900 Ki 3.57 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1CCCC1 CHEMBL3642917 Ki 3.6 nM
CCCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642949 Ki 3.6 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cccnc1 CHEMBL3672852 Ki 3.6 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCC#N CHEMBL3672875 Ki 3.65 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccccc1C(=O)O CHEMBL3672885 Ki 3.65 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1 CHEMBL3642926 Ki 3.7 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)O)s2)c(F)c1 CHEMBL3642980 Ki 3.7 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)ccc1C(=O)O CHEMBL3672887 Ki 3.72 nM
N#Cc1cccc(OC(=O)c2ccc(NC(=N)N)cc2)c1 CHEMBL542261 I50 3.8 nM
CC1(C)C2CC1[C@]1(C)OB([C@H](CCCN=C(N)N)NC(=O)c3cccc(-c4cccc(NS(C)(=O)=O)c4)c3)O[C@@H]1C2 CHEMBL43140 Ki 3.8 nM
CC(C)N(CC(=O)N[C@@H](CCCCN)B(O)O)C(=O)CCc1ccccc1 CHEMBL330206 Ki 3.8 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642908 Ki 3.8 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NN(CC(=O)O)CC(=O)O CHEMBL3642939 Ki 3.8 nM
CCC[C@H](NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667907 Ki 3.84 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@H]1CC(=O)O CHEMBL3672854 Ki 3.88 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3672855 Ki 3.88 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(F)(F)C1 CHEMBL3672859 Ki 3.89 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(Br)cc2)cc1 CHEMBL358868 I50 3.9 nM
CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL340183 Ki 4.0 nM
NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)C(NS(=O)(=O)Cc2ccccc2)C(c2ccccc2)c2ccccc2)CC1 CHEMBL436454 Ki 4.0 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)N[C@@H](CC(=O)O)C(=O)O)CCCC3)s2)c(F)c1 CHEMBL3667880 Ki 4.1 nM
C=CCN(CC(=O)O)C(=O)/C(C)=C/c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)cc1 CHEMBL85154 IC50 4.13 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(-c5cccc(N)c5)nc4Cc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2373348 Ki 4.2 nM
Cc1cc(-c2ccccc2)ccc1C(=O)N[C@@H](CCCN=C(N)N)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL289318 Ki 4.2 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)co1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642927 Ki 4.2 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2cnnc3ccccc23)NS(=O)(=O)Cc2ccccc2)C1O CHEMBL325869 IC50 4.21 nM
Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C(=N)N)s1 CHEMBL277695 Ki 4.4 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)s3)s2)cc1 CHEMBL3642975 Ki 4.4 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)OC)c1 CHEMBL3672879 Ki 4.4 nM
CC(C)(C)NC(=O)N1CCN(C(=O)N2C(=O)[C@H](CCCN=C(N)N)[C@H]2C(=O)O)CC1 CHEMBL71037 IC50 4.5 nM
CC(C)CCNC(=O)C(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642914 Ki 4.5 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)co1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642930 Ki 4.5 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CCC(=O)O)CC(=O)O)s2)c(F)c1 CHEMBL3642953 Ki 4.5 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc[nH]c1=O CHEMBL3672853 Ki 4.54 nM
CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL590799 IC50 4.6 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CCC1 CHEMBL3672892 Ki 4.67 nM
CC1(C)C2CC1[C@]1(C)OB([C@H](CCCN=C(N)N)NC(=O)c3ccc(-c4ccccc4)c(N)c3)O[C@@H]1C2 CHEMBL289147 Ki 4.7 nM
N=C(N)c1ccc2[nH]c(-c3cc(Cl)cc(-c4cccc(N)c4)c3O)nc2c1 CHEMBL73737 Ki 4.7 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642892 Ki 4.76 nM
CC(C)COC(=O)OC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N[C@@H](C)C(=O)NCc1ccc(C(=N)N)cc1 CHEMBL433510 Ki 4.8 nM
C[S+]([O-])Cc1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373475 Ki 4.8 nM
CC1(C)C2CC1[C@]1(C)OB([C@H](CCCN=C(N)N)NC(=O)c3ccc(-c4ccccc4)c([N+](=O)[O-])c3)O[C@@H]1C2 CHEMBL263204 Ki 4.8 nM
CCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL24907 Ki 5.0 nM
CCc1nc2c([N+](=O)[O-])c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL25073 Ki 5.0 nM
CC(Cc1csc(C(=O)Oc2ccc(C(=N)N)cc2)c1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642971 Ki 5.0 nM
CNC(=O)[C@@H]1C[C@H](N2CCc3c(ncnc3OCCc3ccccc3)C2)CN1C(=O)c1ccc(CN)c(OC)c1 CHEMBL4443722 IC50 5.0 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCCC(=O)O CHEMBL3639717 Ki 5.17 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)C(C)C CHEMBL3667891 Ki 5.18 nM
CC1(C)C2CC1[C@]1(C)OB([C@H](CCCN=C(N)N)NC(=O)c3ccc(-c4ccccc4)cc3N)O[C@@H]1C2 CHEMBL296663 Ki 5.3 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(O)c(C(=O)O)c1 CHEMBL3892801 Ki 5.32 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CC#N)nc4Cc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2375178 Ki 5.6 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCc1ccccc1 CHEMBL3642913 Ki 5.7 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NCC(=O)O CHEMBL3642897 Ki 5.75 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCC[C@H](N)C(=O)O CHEMBL3672865 Ki 5.78 nM
CC(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL556199 Ki 6.0 nM
CNC(=O)[C@@H]1C[C@H](N2CCc3c(ncnc3OCCC3CC3)C2)CN1C(=O)c1ccc(CN)c(OC)c1 CHEMBL4475942 IC50 6.0 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NCC(=O)O CHEMBL3642891 Ki 6.34 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2o1 CHEMBL28968 IC50 6.4 nM
N=C(N)c1cccc(-n2nnnc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 CHEMBL332157 Ki 6.4 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CNC=O)nc4Cc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2373559 Ki 6.6 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(CCC(=O)O)C(=O)O)o2)cc1 CHEMBL3642925 Ki 6.7 nM
CCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1C/C(C)=C/c1cccc(N)c1 CHEMBL24565 Ki 6.9 nM
CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL421643 Ki 7.0 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CCC(=O)O)nc4Cc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2373400 Ki 7.1 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)O CHEMBL3642893 Ki 7.19 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCCO)CC(=O)O CHEMBL3642863 Ki 7.32 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N(CCCO)CCS(=O)(=O)O CHEMBL3642894 Ki 7.36 nM
CC1(C)C2CC1[C@]1(C)OB([C@H](CCCN=C(N)N)NC(=O)c3cccc(-c4ccccc4)c3)O[C@@H]1C2 CHEMBL290363 Ki 7.4 nM
CCCN(CC(=O)O)C(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667898 Ki 7.91 nM
CN[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N CHEMBL273196 IC50 8.0 nM
CNC(=O)[C@@H]1C[C@H](N2CCc3c(cccc3OCCOC)C2)CN1C(=O)c1ccc(CN)c(OC)c1 CHEMBL4550207 IC50 8.0 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCCCC(=O)O CHEMBL3672883 Ki 8.01 nM
CC(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL124571 Ki 8.1 nM
CC(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL256892 Ki 8.1 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(Cl)cc2)cc1 CHEMBL357455 I50 8.2 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O CHEMBL3667894 Ki 8.3 nM
C=CCc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)c(OC)c1 CHEMBL149157 I50 8.4 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CC#N)nc4Cc4ccccc4[N+](=O)[O-])O[C@@]3(C)[C@H]1C2 CHEMBL2373405 Ki 8.4 nM
NCCCC[C@H](NC(=O)CN(C(=O)CCc1ccccc1)C1CCCCC1)B(O)O CHEMBL419892 Ki 8.4 nM
N=C(N)c1ccc(CNC(=O)[C@@H]2Cc3ccc(cc3)NC(=O)CCN3CCN(CCC(=O)Nc4ccc(cc4)C[C@@H](NS(=O)(=O)Cc4ccccc4)C(=O)N2)CC3)cc1 CHEMBL2315243 Ki 8.4 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)cs1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642969 Ki 8.5 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3cc(C(=O)NC(Cc4ccccc4)C(=O)O)[nH]c3c2)cc1 CHEMBL3973384 IC50 8.6 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)NC(C=O)CCCN=C(N)N)c1ccc2ccccc2c1 CHEMBL110780 IC50 9.0 nM
CC(=O)N1CC=C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL421466 Ki 9.1 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCO)Cc1ccccc1 CHEMBL3642864 Ki 9.15 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1ccc(C(=O)O)cc1 CHEMBL3672866 Ki 9.27 nM
CC(C)C(=O)NCc1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373346 Ki 9.6 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)c1ccccc1 CHEMBL318998 IC50 9.8 nM
CC(=O)N1CC(=O)C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL127773 Ki 9.9 nM
CCc1nc2c(N(C)C)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL24012 Ki 10.0 nM
N=C(N)NCCC[C@@H](NC(=O)CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1=O)C(=O)c1nccs1 CHEMBL159695 IC50 10.8 nM
Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL289389 IC50 10.9 nM
CCSc1cc(-c2cc(C(=O)Nc3ccccc3)cc3ccc(C(=N)N)cc23)co1 CHEMBL104211 Ki 11.0 nM
CC(C)Oc1cc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)cc(OC2CCCC2)c1 CHEMBL418839 Ki 11.0 nM
COc1cc(C(=O)N2C[C@@H](n3cc(C4CC4)nn3)C[C@H]2C(=O)NCC(c2ccccc2)c2ccccc2)ccc1CN CHEMBL4476255 IC50 11.0 nM
C=CCN(CC(=O)OCC)C(=O)/C(C)=C/c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)cc1 CHEMBL85136 IC50 11.2 nM
N=C(N)N1CCC[C@H](NC(=O)C2CS[C@H]3CC[C@H](NS(=O)(=O)Cc4ccccc4)C(=O)N23)C1O CHEMBL112727 IC50 11.6 nM
COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3OC)c2=O)c1 CHEMBL416912 Ki 11.9 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CC#N)nc4CCc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2373408 Ki 12.0 nM
Cc1nc(C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CC[C@H]3CN(C(=O)CCc4ccccc4)CC(=O)N32)sc1CCO CHEMBL355428 IC50 12.0 nM
CC(C)Oc1cccc(NC(=O)c2cc(C3CCOC3)c3cc(C(=N)N)ccc3c2)c1 CHEMBL421214 Ki 12.0 nM
Cc1ccc(NS(=O)(=O)Cc2ccccc2F)c(=O)n1CC(=O)N[C@H](CCCN=C(N)N)C(=O)O CHEMBL431292 Ki 12.4 nM
CC(C)(C)OC(=O)Nc1cccc(-c2ccc(C(=O)N[C@@H](CCCN=C(N)N)B3O[C@@H]4CC5CC(C5(C)C)[C@]4(C)O3)s2)c1 CHEMBL276881 Ki 13.0 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)c1ccsc1 CHEMBL2370418 IC50 13.0 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)C1CCCCC1 CHEMBL319930 IC50 13.0 nM
CC(C)Oc1cc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)cc(OC(C)C)c1 CHEMBL111543 Ki 13.0 nM
N=C(N)N1CCCC(C[C@H](NC(=O)CN2C(=O)CN(CCCc3ccccc3)C(=O)[C@@H]2Cc2ccc3ccccc3c2)C(=O)c2nccs2)C1 CHEMBL311198 Ki 13.5 nM
Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C(=N)N)s1 CHEMBL19666 Ki 13.6 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N CHEMBL104472 IC50 14.0 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)NC(C=O)CCCN=C(N)N)c1cccc2ccccc12 CHEMBL110898 IC50 14.0 nM
NCCCC[C@H](NC(=O)[C@@H]1CC[C@H]2CN(C(=O)CCc3ccccc3)CC(=O)N21)C(=O)c1nccs1 CHEMBL355060 IC50 14.0 nM
COC(=O)c1ccccc1CS(=O)(=O)N[C@H](CC1CCCN(C(=N)N)C1)C(=O)NCC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL352119 IC50 15.0 nM
CCc1nc2c(N(CC(=O)O)CC(=O)O)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL281591 Ki 15.0 nM
CC(C)(C)OC(=O)NC(C(=O)N1CCC[C@H]1C(=O)NC(C=O)CCCN=C(N)N)c1ccc(Cl)c(Cl)c1 CHEMBL108670 IC50 15.0 nM
CC(=O)N1C[C@H](O)C[C@H]1C(=O)NC(CCCN)C(=O)c1nc2ccccc2s1 CHEMBL339764 Ki 16.0 nM
Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)n(-c2cccc(C(=N)N)c2)n1 CHEMBL37251 Ki 16.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(C(F)(F)F)cc2)cc1 CHEMBL356950 I50 16.4 nM
COc1cccc(OC(=O)c2ccc(NC(=N)N)cc2)c1 CHEMBL357708 I50 16.5 nM
N=C(N)C1CCC[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)c3ccccc3)C2=O)C1O CHEMBL140890 IC50 16.6 nM
COC(=O)c1ccc(F)cc1CS(=O)(=O)Nc1ccc(C)n(CC(=O)N[C@H](CCCN=C(N)N)C(=O)O)c1=O CHEMBL19831 Ki 16.6 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)c1ccc(O)cc1 CHEMBL321322 IC50 17.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2)cc1 CHEMBL273264 IC50 17.0 nM
COC(=O)CC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL327404 Ki 17.0 nM
CC(C)(C)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL146905 I50 17.1 nM
CC(C)c1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL149135 I50 17.2 nM
CN[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)c1ccccc1 CHEMBL105205 IC50 18.0 nM
N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cn3)C2)c1 CHEMBL7651 Ki 18.0 nM
CNC(=N)NCCC[C@H](NC(=O)CN(C)C(=O)CCc1ccccc1)B(O)O CHEMBL431814 Ki 18.0 nM
CCCCCCc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1O CHEMBL440176 I50 18.5 nM
COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3)c2=O)c1 CHEMBL19453 Ki 18.7 nM
COc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL148731 I50 19.0 nM
N=C(N)NCCC[C@@H](C=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]1Cc2ccccc2CN1 CHEMBL2370424 IC50 19.0 nM
CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)c1ccc(F)cc1 CHEMBL102216 IC50 19.0 nM
CC(C)(C)OC(=O)NC(C(=O)N1CCC[C@H]1C(=O)NC(C=O)CCCN=C(N)N)c1cccc(C(F)(F)F)c1 CHEMBL320988 IC50 19.0 nM
NC(N)=NCCC[C@@H](C=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)c1ccccc1 CHEMBL104305 IC50 19.0 nM
COc1cc(C(=O)N2C[C@@H](n3cc(C4CC4)nn3)C[C@H]2C(=O)N[C@H]2CCCC[C@@H]2c2ccccc2)ccc1CN CHEMBL4441232 IC50 19.0 nM
Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL151454 I50 19.5 nM
Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C(=N)N)cc1 CHEMBL19359 Ki 19.7 nM
CCOC(=O)c1cc2ccc(OC3CCN(C(C)=N)CC3)cc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL433600 Ki 20.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccc(CN)cc3)cc(Nc3ncccn3)c2c1 CHEMBL104166 Ki 20.0 nM
Cc1c(S(=O)(=O)N2CCN(CC(=O)NC(CCCN=C(N)N)C(=O)c3nccs3)C(=O)C2)sc2ccc(Cl)cc12 CHEMBL423810 IC50 20.0 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCn1ccnc1N)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL353712 Ki 20.0 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2cnc3ccccc3c2)NC(=O)OCc2ccccc2)C1O CHEMBL324485 IC50 20.38 nM
N=C(N)NCCCC(NC(=O)CN1CCN(S(=O)(=O)c2ccc3c(Cl)cccc3c2)CC1=O)C(=O)c1nccs1 CHEMBL350587 IC50 20.5 nM
N=C(N)NCCC[C@@H](NC(=O)Cn1cccc(NS(=O)(=O)Cc2ccccc2F)c1=O)C(=O)O CHEMBL19599 Ki 20.8 nM
CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1C/C=C/c1cccc(N)c1 CHEMBL24460 Ki 21.0 nM
CN(CC(=O)N[C@@H](CCC/N=C\N)B(O)O)C(=O)CCc1ccccc1 CHEMBL95993 Ki 21.0 nM
CCCCOc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL147344 I50 22.3 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CC#N)nc4Cc4cccc([N+](=O)[O-])c4)O[C@@]3(C)[C@H]1C2 CHEMBL2373403 Ki 23.0 nM
N=C(N)NCCC[C@@H](C=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1NCCc2ccccc21 CHEMBL2370421 IC50 23.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccccc2)cc1 CHEMBL149324 I50 23.4 nM
CC(=O)Nc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL539058 I50 23.7 nM
CCc1nc2c(N)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL277204 Ki 24.0 nM
CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N)c1ccc(F)cc1 CHEMBL2370416 IC50 24.0 nM
Cc1csc(C(=O)C(CCCN=C(N)N)NC(=O)[C@@H]2CC[C@H]3CN(C(=O)CCc4ccccc4)CC(=O)N32)n1 CHEMBL169067 IC50 24.0 nM
N=C(N)N1CCC(C(NS(=O)(=O)Cc2ccccc2)C(=O)NCC(=O)N[C@H]2CCCN(C(=N)N)C2O)CC1 CHEMBL163251 IC50 25.0 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL544222 IC50 25.0 nM
CCc1nc2c(NC(C)=O)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 CHEMBL280769 Ki 25.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2ccc(C(=O)N[C@@H](CCCN=C(N)N)B3O[C@@H]4CC5CC(C5(C)C)[C@]4(C)O3)o2)c1 CHEMBL297536 Ki 25.0 nM
CCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL1183796 Ki 25.0 nM
C=CC[C@@H]1C(=O)O[C@H]2CCC[C@@H]21 CHEMBL102115 IC50 26.0 nM
N=C(N)N1CCC[C@H](NC(=O)CN2C(=O)[C@@H](NS(=O)(=O)Cc3ccccc3)CCc3ccccc32)C1O CHEMBL314576 IC50 26.0 nM
N=C(N)N1CCC[C@H](NC(=O)Cn2cccc(NS(=O)(=O)Cc3ccccc3)c2=O)C1O CHEMBL41267 IC50 26.2 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2ccc(O)nc2)NS(=O)(=O)Cc2ccccc2)C1O CHEMBL331807 IC50 26.6 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCn1ccnc1)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL606957 Ki 27.0 nM
COc1ccc2c(c1)CC[C@H](NS(=O)(=O)c1ccc3ccccc3c1)C(=O)N2CC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL316213 IC50 27.0 nM
COC(=O)c1cccc(OC(=O)c2ccc(NC(=N)N)cc2)c1 CHEMBL542258 I50 27.1 nM
N=C(N)Nc1ccc(C(=O)Oc2cccc3cccnc23)cc1 CHEMBL543454 I50 27.7 nM
CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NC(C=O)CCCN=C(N)N)c1cccc2ccccc12 CHEMBL109109 IC50 29.0 nM
N[C@H]1CC[C@H](C(NC(=O)[C@@H]2CC[C@H]3CN(S(=O)(=O)Cc4ccccc4)CC(=O)N32)C(=O)C(=O)NCC(=O)O)CC1 CHEMBL3084834 Ki 29.0 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2cnccn2)NC(=O)OCc2ccccc2)C1O CHEMBL116245 IC50 30.0 nM
CCN(CC)C(=O)c1cccc(-c2ccc3c(c2)C[C@H]2[C@H]3[C@@H](CCCCC(=N)N)C(=O)N2C(=O)OC)c1 CHEMBL46845 IC50 30.0 nM
N=C(N)NCCCC(NC(=O)C1CCCC1)C(=O)c1nc2ccccc2s1 CHEMBL340547 Ki 30.0 nM
CC(=N)N1CCC(Oc2ccc3cc(C(=O)NC(CC(=O)O)C(=O)O)n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)CC1 CHEMBL173480 Ki 30.0 nM
N=C(N)c1ccc2ccc(Cn3c4ccccc4c4ccc(OC5CCNCC5)cc43)cc2c1 CHEMBL174702 Ki 30.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccccc3)cc(C3CCOC3)c2c1 CHEMBL105395 Ki 30.0 nM
N=C(N)NCCC[C@H](NC(=O)C1CCCC1)C(=O)c1nc2ccccc2s1 CHEMBL164138 Ki 30.0 nM
N=C(N)N1CCCC(C[C@@H](NS(=O)(=O)Cc2ccccc2)C(=O)NCC(=O)N[C@H]2CCCN(C(=N)N)C2O)C1 CHEMBL162443 IC50 31.0 nM
N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cn3)C2)c1 CHEMBL93210 Ki 31.0 nM
COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3F)c2=O)c1 CHEMBL279199 Ki 31.3 nM
CCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1C/C=C/c1cccc(N)c1 CHEMBL25484 Ki 32.0 nM
N=C(N)c1ccc(CNC(=O)Cn2c(-c3cccc(N)c3)c(Cl)nc(NC3CCC3)c2=O)cc1 CHEMBL77490 IC50 32.0 nM
CC(C)=CC(=O)C[C@@H]1C(=O)O[C@H]2CCCC21 CHEMBL318001 IC50 33.0 nM
N=C(N)N1CCCC(C[C@@H](NS(=O)(=O)Cc2ccccc2C(=O)O)C(=O)NCC(=O)N[C@H]2CCCN(C(=N)N)C2O)C1 CHEMBL435448 IC50 33.0 nM
CC1(C)C2CC1[C@]1(C)OB([C@H](CCCN=C(N)N)NC(=O)c3ccc(-c4ccccc4)cc3)O[C@@H]1C2 CHEMBL276880 Ki 33.0 nM
N=C(N)NCCC[C@@H](NC(=O)CN1CCN(S(=O)(=O)Cc2ccccc2)CC1=O)C(=O)c1nccs1 CHEMBL162461 IC50 33.0 nM
CC1(C)[C@@H]2C[C@H]3OB([C@H](CCCCN)NC(=O)Cn4nc(CC#N)cc4CCc4ccccc4)O[C@@]3(C)[C@H]1C2 CHEMBL2373351 Ki 35.0 nM
CC(C)(C)OC(=O)Nc1cccc(-c2cccc(C(=O)N[C@@H](CCCN=C(N)N)B3O[C@@H]4CC5CC(C5(C)C)[C@]4(C)O3)c2)c1 CHEMBL290720 Ki 35.0 nM
Cn1nnnc1C(=O)C(NC(=O)[C@@H]1CC[C@H]2CN(S(=O)(=O)Cc3ccccc3)CC(=O)N21)[C@H]1CC[C@H](N)CC1 CHEMBL3084836 Ki 35.0 nM
CC(C)(C)OC(=O)/C=C/c1nc(Cc2ccccc2)n(CC(=O)N[C@@H](CCCCN)B2O[C@@H]3C[C@@H]4C[C@@H](C4(C)C)[C@]3(C)O2)n1 CHEMBL2373345 Ki 36.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](CC1CCCCC1)NC(=O)c1ccc(-c2cccc(CN)c2)cc1 CHEMBL45106 Ki 36.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2cccc[n+]2C)cc1 CHEMBL44586 Ki 36.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2cccc[n+]2[O-])cc1 CHEMBL46708 Ki 36.0 nM
COS(=O)(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL124809 Ki 38.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](CC(C)C)NC(=O)c1ccc(-c2cccc(CN)c2)cc1 CHEMBL44831 Ki 38.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccc4c(c3)C(C3CCCC3)NCC4)ccc2c1 CHEMBL111338 Ki 39.0 nM
N=C(N)NCCCC(NC(=O)CN1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1=O)C(=O)c1nccs1 CHEMBL163174 IC50 39.1 nM
N=C(N)CCCC[C@H]1C(=O)O[C@H]2CCC[C@@H]21 CHEMBL323543 IC50 40.0 nM
CN1CCCCCOc2ccc(Cl)cc2CNC(=O)Cn2c(Cl)cnc(c2=O)N[C@@H](Cc2ccccc2)C1 CHEMBL92615 Ki 40.0 nM
CC(=N)N1CCC(Oc2ccc3c4ccccc4n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)CC1 CHEMBL369251 Ki 40.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccccc3)cc(Nc3ncccn3)c2c1 CHEMBL104505 Ki 40.0 nM
CCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL318112 Ki 40.0 nM
CCCCS(=O)(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCn1ccnc1N)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 CHEMBL606954 Ki 40.0 nM
COc1ccc2c(c1)N(CC(=O)N[C@H]1CCCN(C(=N)N)C1O)C(=O)[C@@H](NS(=O)(=O)Cc1ccccc1)CC2 CHEMBL315454 IC50 40.0 nM
COc1cc([C@@H](Nc2ccc(C(=N)N)cc2)C(=O)N[C@H](C(=O)O)c2ccccc2)ccc1OCc1ccccc1 CHEMBL178616 Ki 40.0 nM
Cc1cnc(C(=O)NCC[C@@H](NC(=O)OCc2ccccc2)C(=O)NCC(=O)N[C@H]2CCCN(C(=N)N)C2O)cn1 CHEMBL115707 IC50 40.3 nM
C=CC[C@H]1C(=O)O[C@H]2CCC[C@@H]21 CHEMBL100672 IC50 41.0 nM
N=C(N)c1ccc2cnn(CC(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cn3)c2c1 CHEMBL136100 Ki 41.0 nM
CC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL92609 Ki 41.0 nM
CC(C)OC(=O)c1ccccc1CS(=O)(=O)N[C@H]1CCCCN(CC(=O)N[C@H]2CCCN(C(=N)N)C2O)C1=O CHEMBL332537 IC50 41.3 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2ccc(C(N)=O)cc2)cc1 CHEMBL45267 Ki 42.0 nM
CC(C)C1=NCCc2ccc(NC(=O)c3ccc4cc(C(=N)N)ccc4c3)cc21 CHEMBL109367 Ki 42.0 nM
CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1C/C=C/c1cc(N)ccc1O CHEMBL25477 Ki 43.0 nM
CC(C)C1NCCc2ccc(NC(=O)c3ccc4cc(C(=N)N)ccc4c3)cc21 CHEMBL442201 Ki 43.0 nM
N=C(N)c1ccc(CNC(=O)[C@@H]2Cc3ccc(cc3)NC(=O)CN3CCN(CC3)CC(=O)Nc3ccc(cc3)C[C@@H](NS(=O)(=O)Cc3ccccc3)C(=O)N2)cc1 CHEMBL2315239 Ki 44.0 nM
N=C(N)NCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC1CCCCC1)NCC(=O)O CHEMBL3216390 Ki 45.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccccc3)cc(-c3ccoc3)c2c1 CHEMBL319047 Ki 45.0 nM
COCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL92909 Ki 45.0 nM
N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 CHEMBL159418 Ki 45.0 nM
N=C(N)c1ccc2ncn(CC(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)c2c1 CHEMBL343495 Ki 47.0 nM
N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3Cl)C2)c1 CHEMBL323309 Ki 47.0 nM
N=C(N)c1cccc(C2=NOC(Cn3cncn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 CHEMBL436684 Ki 47.0 nM
CCCNS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(Cn3cnnn3)CC(c3cccc(C(=N)N)c3)=NO2)cc1 CHEMBL264626 Ki 49.0 nM
CNS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(Cn3cnnn3)CC(c3cccc(C(=N)N)c3)=NO2)cc1 CHEMBL321530 Ki 49.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N2 CHEMBL4162159 Ki 49.0 nM
Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C(=N)N)cc1 CHEMBL19731 Ki 49.3 nM
COc1cc([C@@H](Nc2ccc(C(=N)N)cc2)C(=O)N[C@H](C(=O)O)c2ccccc2)c(S(=O)(=O)c2ccccc2)cc1OCc1ccccc1 CHEMBL178134 Ki 50.0 nM
CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 CHEMBL85164 IC50 50.6 nM
CC(C)Oc1cccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)c1 CHEMBL111471 Ki 51.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2ccccn2)cc1 CHEMBL295010 Ki 51.0 nM
N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)c4cccs4)CC3)C2=O)c1 CHEMBL104995 Ki 52.0 nM
COC(=O)[C@@H]1CN(Cc2ccc(-c3ccccc3S(N)(=O)=O)cc2)C[C@H]1c1cccc(C(=N)N)c1 CHEMBL18225 Ki 52.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2ccc[n+](C)c2)cc1 CHEMBL295454 Ki 52.0 nM
CS(=O)(=O)NC1(Cc2ccccc2)CCCN(CC(=O)N[C@H]2CCCN(C(=N)N)C2O)C1=O CHEMBL79832 IC50 52.2 nM
CC(=O)N1CC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2s1 CHEMBL339703 Ki 53.0 nM
COc1ccc2cc(S(=O)(=O)NN(Cc3cccc(C(=N)N)c3)C(=O)N3CCCCCC3)ccc2c1 CHEMBL41947 Ki 53.0 nM
CCSCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL327201 Ki 54.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)O)cc2)cc1 CHEMBL433135 IC50 55.0 nM
CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NC(CCCN=C(N)N)B(O)O CHEMBL1202108 Ki 55.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3cccc(OC4CCCC4)c3)ccc2c1 CHEMBL111575 Ki 56.0 nM
N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)Cc4ccccn4)CC3)C2=O)c1 CHEMBL1160792 Ki 57.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccc4c(c3)C(C3CCCC3)=NCC4)ccc2c1 CHEMBL323387 Ki 58.0 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2ccc3ccccc3n2)NS(=O)(=O)Cc2ccccc2)C1O CHEMBL117716 IC50 59.2 nM
N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)c4ccccc4)CC3)C2=O)c1 CHEMBL102502 Ki 60.0 nM
CC(=N)N1CCC(Oc2ccc3cc(C(=O)O)n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)CC1 CHEMBL176568 Ki 60.0 nM
CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cccc(CN)c2)c(F)c1 CHEMBL559015 Ki 60.0 nM
CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cccc(CN)c2)c(F)c1 CHEMBL176140 Ki 60.0 nM
CC(C)(C)NC(=O)N1CCN(C(=O)N2C(=O)[C@H](CC3CCNCC3)[C@H]2C(=O)O)CC1 CHEMBL70155 IC50 62.0 nM
CC[C@@H](NC(=O)c1ccc(-c2cccc(CN)c2)cc1)[C@@H](Cc1cccc(C(=N)N)c1)C(=O)OC CHEMBL48610 Ki 63.0 nM
COC(=O)OC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)NCc1ccc(C(=N)N)cc1 CHEMBL159162 Ki 64.0 nM
CC(C)Nc1nc(Cl)c(-c2cc(N)cc(C(=O)O)c2)n(CC(=O)NCc2ccc(C(=N)N)cc2)c1=O CHEMBL77076 IC50 64.0 nM
COC(=O)c1ccccc1OC(=O)c1ccc(NC(=N)N)cc1 CHEMBL148957 I50 65.0 nM
CCN(CC)C(=O)c1cccc(-c2ccc3c(c2)[C@@H]2[C@@H](CCCCC(=N)N)C(=O)N(S(=O)(=O)c4ccccc4)[C@H]2C3)c1 CHEMBL297169 IC50 66.0 nM
CCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1Cc1cccc(-c2cccc(C(=N)N)c2)c1 CHEMBL25527 Ki 67.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](CCc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL45407 Ki 67.0 nM
COC(=O)[C@@H]1CN(Cc2ccc(-c3ccccc3S(N)(=O)=O)cc2)O[C@H]1c1cccc(C(=N)N)c1 CHEMBL279267 Ki 69.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL45000 Ki 69.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2cccc(CN)c2)cc1 CHEMBL48046 Ki 69.0 nM
NCc1cccc(-n2nnnc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 CHEMBL122796 Ki 69.0 nM
CC(C)=CC(=O)C[C@H]1C(=O)O[C@H]2C[C@]3(C)C4=CC[C@@H]5[C@](C)(CC[C@H]6OC(=O)[C@@]56C)[C@H]4CC[C@@]3(C)[C@@H]21 CHEMBL457155 IC50 70.0 nM
CC1(C)OB([C@H](CCCN=C(N)N)NC(=O)c2ccccc2)OC1(C)C CHEMBL418427 Ki 70.0 nM
COCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL328298 Ki 70.0 nM
CCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL328582 Ki 70.0 nM
CCS(=O)(=O)CC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL93744 Ki 72.0 nM
CCS(=O)(=O)CC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL406295 Ki 72.0 nM
CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1C/C(C)=C/c1cccc(N)c1 CHEMBL25478 Ki 73.0 nM
CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1Cc1ccc(-c2cccc(C(=N)N)c2)cc1 CHEMBL24780 Ki 73.0 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2cn[nH]c2)NC(=O)OCc2ccccc2)C1O CHEMBL419222 IC50 74.5 nM
N=C(N)C1CCC[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O CHEMBL343805 IC50 74.5 nM
CN(CC(=O)N[C@H]1CCCC(C(=N)N)C1O)C(=O)[C@@H](CCCN=C(N)N)NS(=O)(=O)Cc1ccccc1 CHEMBL431985 IC50 74.7 nM
N=C(N)NCCCC(NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL117672 IC50 75.0 nM
N=C(N)NCCC[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)NCC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL423823 IC50 75.0 nM
N=C(N)c1ccc2[nH]c(-c3cc([N+](=O)[O-])cc(-c4ccccc4)c3O)cc2c1 CHEMBL94775 Ki 75.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](Cc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL43264 Ki 75.0 nM
N=C(N)N1CCC[C@H](NC(=O)CN2CCCC[C@H](NS(=O)(=O)Cc3ccccc3)C2=O)C1O CHEMBL84575 IC50 75.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2ccncc2)cc1 CHEMBL296046 Ki 76.0 nM
COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3Cl)c2=O)c1 CHEMBL283555 Ki 76.5 nM
COc1cccc2c1CC[C@H](NS(=O)(=O)Cc1ccccc1)C(=O)N2CC(=O)N[C@H]1CCCN(C(=N)N)C1O CHEMBL87502 IC50 77.0 nM
CCCOC(=O)c1ccccc1CS(=O)(=O)N[C@H]1CCCCN(CC(=O)N[C@H]2CCCN(C(=N)N)C2O)C1=O CHEMBL122920 IC50 79.8 nM
N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)Cc4ccccc4)CC3)C2=O)c1 CHEMBL103993 Ki 80.0 nM
O=C1Cn2c(Cl)cnc(c2=O)N[C@@H](Cc2ccccc2)CNCCCCCOc2ccc(Cl)cc2CN1 CHEMBL418965 Ki 80.0 nM
N=C(N)c1cccc(Oc2ccc3c4ccccc4n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)c1 CHEMBL174735 Ki 80.0 nM
N=C(N)c1cccc(C2=NOC(Cc3ccccc3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 CHEMBL316070 Ki 80.0 nM
COc1cc([C@@H](Nc2ccc(C(=N)N)cc2)C(=O)N[C@H](C(=O)O)c2ccccc2)c(C(=O)Cc2ccccc2)cc1OCc1ccccc1 CHEMBL366921 Ki 80.0 nM
CC(=O)N1C[C@H](O)C[C@H]1C(=O)NC(CCCN=C(N)N)C(=O)c1nccs1 CHEMBL341083 Ki 81.0 nM
CCC1CNCc2ccc(NC(=O)c3ccc4cc(C(=N)N)ccc4c3)cc21 CHEMBL108447 Ki 82.0 nM
N=C(N)c1cccc(C2=NOC(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 CHEMBL92523 Ki 83.0 nM
CCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL1184021 Ki 86.0 nM
COc1ccccc1OC(=O)c1ccc(NC(=N)N)cc1 CHEMBL148833 I50 87.6 nM
N=C(N)c1ccc(OCC[C@@H]2CCCCN2C(=O)[C@@H](CC2CCCCC2)NCC(=O)O)cc1 CHEMBL81056 Ki 89.0 nM
O=C1Cn2c(Cl)cnc(c2=O)N[C@@H](Cc2ccccc2)CNCCCCOc2ccc(Cl)cc2CN1 CHEMBL316901 Ki 90.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2cccc(C(N)=O)c2)cc1 CHEMBL44050 Ki 90.0 nM
CN(C)C(=O)COc1ccc2c3ccccc3n(Cc3ccc4ccc(C(=N)N)cc4c3)c2c1 CHEMBL174995 Ki 90.0 nM
CC(=N)N1CCC(Oc2ccc3cc(C(=O)N(C)C)n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)CC1 CHEMBL368072 Ki 90.0 nM
CCCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL327403 Ki 90.0 nM
N=C(N)NCCC[C@H](NC(=O)CN1C(=O)CN(CCCc2ccccc2)C(=O)[C@@H]1Cc1ccccc1)C(=O)c1nccs1 CHEMBL315550 IC50 90.0 nM
CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1Cc1ccc(-c2ccc(C(=N)N)cc2)cc1 CHEMBL25184 Ki 91.0 nM
N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 CHEMBL328069 Ki 91.0 nM
N=C(N)c1cccc(C2=NOC(Cn3ncnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 CHEMBL91999 Ki 91.0 nM
N=C(N)c1ccc2cc(C(=O)Nc3ccc4c(c3)CCNC4)ccc2c1 CHEMBL111567 Ki 92.0 nM
N=C(N)Nc1ccc(C(=O)Oc2cccc(C(F)(F)F)c2)cc1 CHEMBL150009 I50 92.2 nM
CC(C)OC(=O)[C@@H]1CN(Cc2ccc(-c3ccccc3S(N)(=O)=O)cc2)O[C@H]1c1cccc(C(=N)N)c1 CHEMBL18578 Ki 93.0 nM
NC1CCC(CNC(=O)[C@@H]2CCCN2C(=O)[C@H](N)C(c2ccccc2)c2ccccc2)CC1 CHEMBL416795 Ki 94.0 nM
COC(=O)[C@H](Cc1cccc(C(=N)N)c1)[C@@H](C)NC(=O)c1ccc(-c2cccc(CN(C)C)c2)cc1 CHEMBL47704 Ki 95.0 nM
N=C(N)NCCC[C@H](NC(=O)CN1C(=O)CN(CCCc2ccccc2)C(=O)[C@H]1Cc1ccccc1)C(=O)c1nccs1 CHEMBL313790 IC50 96.0 nM
COC(=O)CC(CCc1ccc(NC(=N)N)cc1)c1cccc(C(=N)N)c1 CHEMBL156161 Ki 96.0 nM
N=C(N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2nccc3ccccc23)NS(=O)(=O)Cc2ccccc2)C1O CHEMBL117092 IC50 97.8 nM
CC(C)OC(=O)[C@@H]1CN(Cc2ccc(-c3ccccc3S(N)(=O)=O)cc2)C[C@H]1c1cccc(C(=N)N)c1 CHEMBL276782 Ki 98.0 nM
COCCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL94052 Ki 98.0 nM
COC(=O)CC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 CHEMBL279628 Ki 98.0 nM
COC(=O)CC(CCc1ccc(C(=N)N)cc1)c1cccc(C(=N)N)c1 CHEMBL156702 Ki 99.0 nM