C[C@H](NC(=O)[C@@H](O)c1cc(F)cc(F)c1)C(=O)N[C@@H]1C(=O)N(C)c2ccccc2-c2ccccc21 CHEMBL392068 EC50 0.114 nM
O=S(=O)(NC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)C(F)(F)F CHEMBL1091513 IC50 0.65 nM
CS(=O)(=O)CC[C@@H]1OCC[C@@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@@H]12 CHEMBL2159511 IC50 1.3 nM
CCS(=O)(=O)CC[C@@H]1OCC[C@@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@@H]12 CHEMBL2159510 IC50 3.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4cc(F)c(C(F)(F)F)c(F)c4)O2)C3=O)cn1 CHEMBL3942982 IC50 3.34 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4cc(F)c(Cl)c(F)c4)O2)C3=O)cn1 CHEMBL3893460 IC50 5.48 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4cc(F)c(Cl)c(Cl)c4)O2)C3=O)cn1 CHEMBL3890783 IC50 5.78 nM
CC(C)S(=O)(=O)CC[C@@H]1OCC[C@@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@@H]12 CHEMBL2159509 IC50 6.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4cc(F)c(Cl)cc4C(F)(F)F)O2)C3=O)cn1 CHEMBL3951810 IC50 7.84 nM
CNC(=O)OCC[C@@H]1OCC[C@@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@@H]12 CHEMBL2159689 IC50 8.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(C(F)(F)F)c(F)c4)O2)C3=O)cn1 CHEMBL3959250 IC50 8.35 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(Cl)cc4C(F)(F)F)O2)C3=O)cn1 CHEMBL3980608 IC50 9.1 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(Cl)c(F)c4C(F)(F)F)O2)C3=O)cn1 CHEMBL3929506 IC50 10.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(C(F)(F)F)c(F)c4F)O2)C3=O)cn1 CHEMBL3948397 IC50 11.0 nM
COc1cc(Cl)c(F)cc1[C@H]1CC[C@@H]([C@H](C)N2CCn3c(ccc(-n4cnc(C)c4)c3=O)C2=O)O1 CHEMBL3978667 IC50 11.1 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4cc(F)c(Cl)cc4F)O2)C3=O)cn1 CHEMBL3962470 IC50 11.4 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4cc(F)c(Cl)c(F)c4)O2)C3=O)cn1 CHEMBL3906008 IC50 13.3 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3955146 IC50 14.3 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(Cl)cc4OC(F)(F)F)O2)C3=O)cn1 CHEMBL3917064 IC50 14.5 nM
COc1cc(C(F)(F)F)ccc1[C@H]1CC[C@@H]([C@H](C)N2CCn3c(ccc(-n4cnc(C)c4)c3=O)C2=O)O1 CHEMBL3976595 IC50 15.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(C(F)(F)F)c(F)c4)O2)C3=O)cn1 CHEMBL3925476 IC50 15.7 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4cc(F)c(C(F)(F)F)c(F)c4)O2)C3=O)cn1 CHEMBL3979115 IC50 16.0 nM
O=S(=O)(c1ccc(Cl)cc1)[C@@]12CCO[C@@H](CCO)[C@@H]1COc1c(F)ccc(F)c12 CHEMBL2159687 IC50 18.0 nM
Cc1cn(-c2ccc3n(c2=O)C[C@H](C)N(C[C@H]2CC[C@@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3968096 IC50 19.8 nM
COc1cc(Cl)ccc1[C@H]1CC[C@@H](CN2CCn3c(ccc(-n4cnc(C)c4)c3=O)C2=O)O1 CHEMBL3985730 IC50 21.6 nM
N#CCC[C@@H]1OCC[C@@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@@H]12 CHEMBL2159691 IC50 22.0 nM
CCNC(=O)OCC[C@@H]1OCC[C@@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@@H]12 CHEMBL2159690 IC50 24.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(F)cc4C(F)(F)F)O2)C3=O)cn1 CHEMBL3924102 IC50 24.2 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(Cl)cc4OC(F)F)O2)C3=O)cn1 CHEMBL3918666 IC50 24.6 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@H]2O[C@@H](c4ccc(C(F)(F)F)cc4)C[C@@H]2C)C3=O)cn1 CHEMBL3906428 IC50 25.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(Cl)cc4C(F)(F)F)O2)C3=O)cn1 CHEMBL3910627 IC50 26.8 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3911070 IC50 27.6 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(C(F)(F)F)cc4Cl)O2)C3=O)cn1 CHEMBL3908938 IC50 29.1 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@H]2CCC[C@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3902117 IC50 29.9 nM
COc1cc(-c2cn([C@H]3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1 CHEMBL3609749 IC50 31.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4cc(F)c(F)cc4C(F)(F)F)O2)C3=O)cn1 CHEMBL3918851 IC50 33.5 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2C[C@H](C)[C@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3890183 IC50 38.4 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@](C)(c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3972571 IC50 40.5 nM
Cc1cn(-c2ccc3n(c2=O)C[C@@H](C)N(C[C@H]2CC[C@@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3938538 IC50 46.4 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(Cl)cc4)O2)C3=O)cn1 CHEMBL3926551 IC50 52.1 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H](C)[C@@H]2CC[C@H](c4ccc(C(F)(F)F)s4)O2)C3=O)cn1 CHEMBL3960512 IC50 52.4 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(OC(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3928795 IC50 60.3 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2cccc4cc(F)c(F)cc24)C3=O)cn1 CHEMBL3896372 IC50 60.6 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(C5CC5)cc4)O2)C3=O)cn1 CHEMBL3953711 IC50 63.8 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccc(C(C)(F)F)cc4)O2)C3=O)cn1 CHEMBL3935522 IC50 73.3 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4ccccc4C(F)(F)F)O2)C3=O)cn1 CHEMBL3913030 IC50 73.3 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2C[C@@H](F)[C@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3980167 IC50 73.5 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2C[C@@H](C)[C@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3949792 IC50 73.5 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CCC[C@H](c4ccc(Cl)cc4)C2)C3=O)cn1 CHEMBL3900856 IC50 80.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@@H]2CC[C@H](c4cccc(C(F)(F)F)c4)O2)C3=O)cn1 CHEMBL3946187 IC50 81.2 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@H]2CCC[C@@H](c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3965573 IC50 96.6 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCCC(c4ccc(Cl)cc4)C2)C3=O)cn1 CHEMBL3935854 IC50 98.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2cccc4ccc(F)cc24)C3=O)cn1 CHEMBL3889603 IC50 112.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(Cl)c(Cl)c4)O2)C3=O)cn1 CHEMBL3935477 IC50 117.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2ccc(Cl)cc2C(F)(F)F)C3=O)cn1 CHEMBL3935655 IC50 120.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CCC[C@@H]2Oc2ccc(F)cc2C(F)(F)F)C3=O)cn1 CHEMBL3890892 IC50 140.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2ccc(F)c(Cl)c2C)C3=O)cn1 CHEMBL3956978 IC50 146.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2cccc(F)c2C(C)C)C3=O)cn1 CHEMBL3912132 IC50 153.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2cccc(C(F)(F)F)c2Cl)C3=O)cn1 CHEMBL3982082 IC50 157.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@H]2CC[C@@H](c4ccc(C(F)(F)C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3898549 IC50 157.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2ccc(Cl)c(C(C)C)c2)C3=O)cn1 CHEMBL3966656 IC50 158.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2ccc(F)c4c2CCC4)C3=O)cn1 CHEMBL3968767 IC50 162.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2cccc4ccccc24)C3=O)cn1 CHEMBL3905374 IC50 164.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCCC2Oc2cccc(C(F)(F)F)c2)C3=O)cn1 CHEMBL3939251 IC50 188.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2ccccc2C(F)(F)F)C3=O)cn1 CHEMBL3975978 IC50 211.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@H]2Oc2cccc(C(F)(F)F)c2)C3=O)cn1 CHEMBL3957731 IC50 217.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2(C)CCC(c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3967275 IC50 236.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CCC[C@H]2Oc2ccccc2C(F)(F)F)C3=O)cn1 CHEMBL3899746 IC50 300.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@H]2C[C@H](COc4ccc(F)cc4C(F)(F)F)C2)C3=O)cn1 CHEMBL3981756 IC50 303.0 nM
O=S(=O)(c1ccc(Cl)cc1)[C@]12CCO[C@H](CCO)[C@H]1COc1c(F)ccc(F)c12 CHEMBL2159688 IC50 320.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CC(c4cc(C(F)(F)F)cc(Cl)c4F)=NO2)C3=O)cn1 CHEMBL3982060 IC50 353.0 nM
CS(=O)(=O)CC[C@H]1OCC[C@]2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OC[C@H]12 CHEMBL2159686 IC50 377.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CC(c4cccc(C(F)(F)F)c4Cl)=NO2)C3=O)cn1 CHEMBL3930235 IC50 429.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CC[C@@H]2Oc2ccccc2C(F)(F)F)C3=O)cn1 CHEMBL3957582 IC50 469.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CC(c4ccc(Cl)c(C(F)(F)F)c4)=NO2)C3=O)cn1 CHEMBL3918962 IC50 483.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CCC[C@@H]2Cc2cc(F)cc(F)c2)C3=O)cn1 CHEMBL3941322 IC50 561.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@@H]2CCC[C@@H]2c2cc(F)cc(F)c2)C3=O)cn1 CHEMBL3974235 IC50 563.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C2CCCCC2Oc2ccc(Cl)cc2)C3=O)cn1 CHEMBL3944609 IC50 591.0 nM
CCCC/C(=C\c1cc(OCc2ccc3nc(C(F)(F)F)cc(OC)c3c2)ccc1OCc1ccc(C(F)(F)F)cc1)C(=O)O CHEMBL3397721 IC50 630.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(CC2CC(c4cc(C(F)(F)F)ccc4Cl)=NO2)C3=O)cn1 CHEMBL3956668 IC50 711.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN(C[C@H]2CC[C@@](C)(c4ccc(C(F)(F)F)cc4)O2)C3=O)cn1 CHEMBL3934015 IC50 725.0 nM
Cc1cn(-c2ccc3n(c2=O)CCN([C@H]2C[C@H](Oc4ccccc4C(F)(F)F)C2)C3=O)cn1 CHEMBL3965759 IC50 789.0 nM
CCCC/C(=C\c1cc(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)ccc1OCc1ccc(C(F)(F)F)cc1)C(=O)O CHEMBL3397717 IC50 790.0 nM
CCCC/C(=C\c1cc(OCc2ccc(OCCN3CCOCC3)cc2)ccc1OCc1ccc(C(F)(F)F)cc1)C(=O)O CHEMBL3397724 EC50 970.0 nM
CC(C)=CCC/C(C)=C/CC/C(C)=C/COC(=O)C1(C)CCc2c(C)c(OCC(=O)O)c(C)c(C)c2O1 CHEMBL2398570 EC50 1000.0 nM
CCCC/C(=C\c1cc(OCC2CCC(C(F)(F)F)CC2)ccc1OCc1ccc(C(F)(F)F)cc1)C(=O)O CHEMBL3397727 IC50 1000.0 nM