CCOC[C@H](CC(C)C)NS(=O)(=O)c1ccc(Cn2c(C)nc3cnccc32)cc1 CHEMBL157078 IC50 0.015 nM
CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(C)=O CHEMBL1235246 Ki 0.15 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL277701 IC50 0.2 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)n(C)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20195 IC50 0.3 nM
CCOC(=O)[C@H](CC(C)C)N(C)S(=O)(=O)c1ccc(Cn2c(C)nc3cnccc32)cc1 CHEMBL322832 Ki 0.38 nM
Cc1nnc2n1-c1sc3c(c1[C@@H](c1ccccc1Cl)NC2)C[C@@H](C(=O)NCc1ccc(C(F)(F)F)cc1)C3 CHEMBL5439289 IC50 0.4 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC21CC1)C[C@H](C(=O)N[C@H]1CCc2ccccc2C1)C3 CHEMBL5408810 IC50 0.4 nM
CCC12CC(NC(=O)[C@@H]3Cc4sc5c(c4C3)[C@H](c3ccccc3Cl)NCc3nnc(C)n3-5)(C1)C2 CHEMBL5433867 IC50 0.5 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC21CC1)C[C@H](C(=O)N[C@H]1CCc2cccc(F)c21)C3 CHEMBL5411872 IC50 0.5 nM
C#Cc1cccc2c1c(C(=O)c1ccc(Cn3c(C)nc4cnccc43)c(F)c1)cn2C(=O)N(C)C CHEMBL369225 Ki 0.57 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)n(C)c(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL19640 IC50 0.6 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC21CC1)C[C@H](C(=O)NC1CCc2ccc(F)cc21)C3 CHEMBL5439944 IC50 0.6 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC21CC1)C[C@H](C(=O)NC1CCc2cc(F)ccc21)C3 CHEMBL5422270 IC50 0.6 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)COc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL19747 IC50 0.7 nM
Cc1nnc2n1-c1sc(C#CCC34CCCc5cccc(c53)NC4=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL20019 IC50 0.7 nM
CCCN(CCC)C(=O)[C@@H]1Cc2sc3c(c2C1)[C@H](c1ccccc1Cl)NCc1nnc(C)n1-3 CHEMBL5425646 IC50 0.7 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC21CC1)C[C@H](C(=O)N(C)C1CCC(C)(C)CC1)C3 CHEMBL5399089 IC50 0.9 nM
CCCN(CCC)C(=O)[C@@H]1Cc2sc3c(c2C1)C(c1ccccc1Cl)=NC1(CC1)c1nnc(C)n1-3 CHEMBL5431916 IC50 0.9 nM
CC(=O)OC[n+]1cccc([C@H]2SCc3c(C(=O)c4cn(C(=O)N(C)C)c5cc(-c6ccc(F)cc6)ccc45)ccn32)c1 CHEMBL317090 Ki 0.98 nM
CCCS(=O)(=O)c1cc(C2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCS(=O)(=O)c1ccccc1 CHEMBL293773 Ki 1.0 nM
CCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)cc(OC)c2ccccc12 CHEMBL99294 IC50 1.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)n(-c4ccccc4)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL281779 IC50 1.0 nM
Cc1nnc2n1-c1sc(C#CCn3ncc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL283162 IC50 1.0 nM
Cc1nnc2n1-c1sc(C#CCn3ccc4ccccc4c3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL282883 IC50 1.0 nM
Cc1nnc2n1-c1sc3c(c1[C@H](c1ccccc1Cl)NC2)C[C@@H](C(=O)NCc1ccccc1)C3 CHEMBL5411707 IC50 1.1 nM
Cc1nnc2n1-c1sc3c(c1[C@@H](c1ccccc1Cl)NC2)C[C@@H](C(=O)NC1(c2ccc(Cl)cn2)CC1)C3 CHEMBL5413888 IC50 1.3 nM
Cc1nnc2n1-c1sc3c(c1[C@@H](c1ccccc1Cl)NC2)C[C@@H](C(=O)NC1CCC(F)(F)CC1)C3 CHEMBL5400532 IC50 1.3 nM
CCCOc1c(OCCCO)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O CHEMBL118105 Ki 1.85 nM
COc1cccc(C(=C/C=C/C(=O)NCCCCc2cccnc2)c2cccc(OC)c2)c1 CHEMBL296149 IC50 2.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1c(F)c(F)cc(F)c1F CHEMBL2113725 IC50 2.0 nM
COc1ccc(/C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)c2ccccc2)cc1 CHEMBL57676 IC50 2.0 nM
CCOC(=O)C1=C(c2ccc(-n3c(C)nc4cnccc43)cc2)NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl CHEMBL29067 IC50 2.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)ccc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL279665 IC50 2.0 nM
O=C([C@@H]1CSC(c2cccnc2)N1)N1CCN(CCCc2ccccc2)CC1 CHEMBL156461 IC50 2.3 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3ccccc32)=NC(C)=C(C(=O)NC(C)(C)C)[C@H]1c1ccccc1Cl CHEMBL104967 IC50 2.3 nM
CCCOc1c(OCCCN2CCOCC2)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O CHEMBL117413 Ki 2.5 nM
CCCOc1c(OC)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)C[C@@H](C)CCCO CHEMBL334115 Ki 2.86 nM
CCCOc1c(OCCCn2ccnc2)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O CHEMBL407427 Ki 3.0 nM
COc1ccc(C2CCC(OCCCn3c(C)nc4cnccc43)O2)cc1Cl CHEMBL34548 IC50 3.0 nM
CCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)cc(OC)c2ccc(OC)cc12 CHEMBL99924 IC50 3.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3ccccc32)=NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl CHEMBL104290 IC50 3.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)Cc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL429066 IC50 3.0 nM
Cc1nnc2n1-c1sc(C#CCOc3ccccc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL20163 IC50 3.0 nM
CCCOc1c(OC)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CCO CHEMBL299944 Ki 3.2 nM
CCCOc1c(OC)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)C[C@H](C)CCCO CHEMBL116072 Ki 3.72 nM
COc1ccc(/C(=C\C=C\C(=O)N[C@H](C)CCCc2cccnc2)c2ccccc2)cc1 CHEMBL52925 IC50 4.0 nM
CCCCc1cc(C(=O)N[C@H](C)CCCc2cccnc2)ccc1-c1ccc(OC)c(OC)c1 CHEMBL51692 IC50 4.0 nM
CCc1cc(C(=O)N[C@H](C)CCCc2cccnc2)ccc1-c1ccc(OC)c(OC)c1 CHEMBL53001 IC50 4.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)COc4cc(F)ccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20418 IC50 4.0 nM
Cc1nnc2n1-c1sc(C#CCOc3cccnc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL283339 IC50 4.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)OCc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20267 IC50 4.0 nM
Cc1nnc2n1-c1sc(C#CCN3Cc4cccc5cccc(c45)C3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL280210 IC50 4.0 nM
Cc1nc2cnccc2n1CCCOC1CCC(c2ccc(Cl)c(Cl)c2)O1 CHEMBL284276 IC50 5.0 nM
CCCCCCCC/C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL415953 IC50 5.0 nM
C#Cc1cc(C(=O)N[C@H](C)CCCc2cccnc2)ccc1-c1ccc(OC)c(OC)c1 CHEMBL430969 IC50 5.0 nM
O=C(NCCCCc1cccnc1)c1ccc(-c2ccccc2)c(-c2ccccc2)c1 CHEMBL53584 IC50 5.0 nM
Cc1nnc2n1-c1sc(C#CCN3CCc4ccccc4C3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL280683 IC50 5.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)c4cccc5cccc3c45)cc1C(c1ccccc1Cl)=NC2 CHEMBL20208 IC50 5.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)COc4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20877 IC50 5.0 nM
Cc1nnc2n1-c1sc(C#CCn3cnc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL277029 IC50 5.0 nM
O=C1c2ccccc2C(=O)N1CC#Cc1ccc2c(c1)C(c1ccccc1F)=NCc1nnc(C(F)(F)F)n1-2 CHEMBL20194 IC50 5.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)COc4ccccc43)cc1C(c1ccccc1F)=NC2 CHEMBL19947 IC50 5.0 nM
CCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)ccc2c(OC)cccc12 CHEMBL317579 IC50 6.0 nM
C=C=Cn1c(=O)n(CC#Cc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)c2ccccc21 CHEMBL282905 IC50 6.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL21224 IC50 6.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)NCc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL435756 IC50 6.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccccc1F)=N[C@H]2C CHEMBL277246 IC50 6.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3ncccc32)=NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl CHEMBL322029 IC50 6.5 nM
COc1ccc([C@H]2CC[C@@H](OCCCn3c(C)nc4cnccc43)O2)cc1OC CHEMBL288329 IC50 7.0 nM
Cc1nc2cnccc2n1CCCOC1CCC(c2ccc(F)cc2)O1 CHEMBL37358 IC50 7.0 nM
CCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)ccc2cc(OC)ccc12 CHEMBL97530 IC50 7.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)CCc4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20323 IC50 7.0 nM
Cc1nnc2n1-c1sc(C#CCn3c4c(c5ccccc53)CCCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL278072 IC50 7.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)C(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20003 IC50 7.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)CSc4ccccc43)cc1C(c1ccccc1F)=NC2 CHEMBL277618 IC50 7.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3ccccc32)=NC(C)=C(C(=O)NC(C)(C)C)C1c1ccccc1Cl CHEMBL104843 IC50 7.5 nM
CCCOc1c(NC(=O)N(O)CC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL347382 IC50 8.0 nM
Cc1nnc2n1-c1sc(CCc3ccc(-c4ccccn4)s3)cc1C(c1ccccc1Cl)=NC2 CHEMBL34461 IC50 8.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3cnccc32)=NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl CHEMBL317911 IC50 8.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3cccnc32)=NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl CHEMBL318391 IC50 8.0 nM
CCCOc1c(OC)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(C)(=O)=O CHEMBL1793831 Ki 9.0 nM
CCCCCC/C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL53527 IC50 9.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(O)nc4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL279234 IC50 9.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)CCc4cc(Cl)cc(Cl)c43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20343 IC50 9.0 nM
Cc1nnc2n1-c1sc(CCC(=O)N3CCOCC3)cc1C(c1ccccc1Cl)=NC2 CHEMBL280164 Ki 9.9 nM
Cc1nc2cnccc2n1CCCOC1CCC(c2ccc(Br)cc2)O1 CHEMBL37357 IC50 10.0 nM
CCCCC/C(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL431744 IC50 10.0 nM
COc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(CNC(=O)N(C)O)c1OCCSc1ccc(Cl)cc1 CHEMBL2113720 IC50 10.0 nM
COc1ccc(C(=C/C=C/C(=O)Nc2ccc(-c3cccnc3)cc2)c2ccc(OC)cc2)cc1 CHEMBL53014 IC50 10.0 nM
COc1cc(CCc2ccc(C3=Cc4ccsc4C4=NCCN34)cc2)cc(OC)c1OC CHEMBL320835 IC50 10.0 nM
CCCCc1ccc(CCc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc1 CHEMBL442259 IC50 10.0 nM
C#Cc1cc2c(s1)-n1c(C)nnc1CN=C2c1ccccc1Cl CHEMBL286217 IC50 10.0 nM
CCCCc1ccc(/C=C\c2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc1 CHEMBL430919 IC50 10.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)=NC2 CHEMBL19801 IC50 10.0 nM
O=C(c1ccccc1)c1cccc(NC(=O)c2ccn3c2CS[C@@H]3c2cccnc2)c1 CHEMBL349811 IC50 11.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)Nc2cccc(C)n2)C1c1ccccc1Cl CHEMBL104978 IC50 11.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)C4(C)CCCc5cccc3c54)cc1C(c1ccccc1Cl)=NC2 CHEMBL283525 IC50 12.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)CC(C)(C)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL417275 IC50 12.0 nM
CCCCCCCCCCCCCCCCCCOC1CC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CO1 CHEMBL290840 IC50 12.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)c4cccc5cccc(c45)C3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL280401 IC50 12.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL277650 IC50 13.0 nM
CCCC/C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL296600 IC50 14.0 nM
COc1ccc(C2CCC(OCCCn3c(C)nc4cnccc43)O2)cc1OC CHEMBL35776 IC50 15.0 nM
COc1ccc(-c2ccc(C(=O)N[C@H](C)CCCc3cccnc3)cc2)cc1OC CHEMBL53585 IC50 15.0 nM
CCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)ccc2ccc(OC)cc12 CHEMBL97630 IC50 15.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)OC)[C@H]1c1ccccc1Cl CHEMBL319839 IC50 15.0 nM
Cc1nnc2n1-c1sc(C#CCn3c4c(c5ccccc53)CCCCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL20644 IC50 15.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)Cn4ccc5c(Cl)ccc3c54)cc1C(c1ccccc1Cl)=NC2 CHEMBL277678 IC50 15.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc43)cc1C(C1=CC(=O)CC=C1Cl)=NC2 CHEMBL418556 IC50 15.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)c4cccc5cccc(c45)C3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL430333 IC50 15.0 nM
CCCOc1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(N(CC)C(=O)N(O)CC)c1OCCC CHEMBL348609 IC50 17.0 nM
CCCOc1c(NC(=O)N(C)O)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL160692 IC50 17.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)Nc2ccccc2)C1c1ccccc1Cl CHEMBL440149 IC50 17.0 nM
CCCCc1cc(C(=O)NCCCCc2cccnc2)ccc1-c1ccc(OC)c(OC)c1 CHEMBL53867 IC50 18.0 nM
COc1cc(C2CCC(OCCCn3c(C)nc4cnccc43)O2)cc(OC)c1OC CHEMBL34182 IC50 20.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1ccc(Cl)cc1 CHEMBL2113727 IC50 20.0 nM
COc1ccc(/C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)C2CCCCC2)cc1 CHEMBL416124 IC50 20.0 nM
COc1ccc(/C(=C\C=C\C(=O)N[C@H](C)CCCc2cccnc2)C2CCCCC2)cc1 CHEMBL52616 IC50 20.0 nM
O=C(/C=C/C=C(c1cccc(F)c1)c1cccc(F)c1)NCCCCc1cccnc1 CHEMBL52834 IC50 20.0 nM
COc1cccc(-c2ccc(C(=O)N[C@H](C)CCCc3cccnc3)cc2)c1 CHEMBL51238 IC50 20.0 nM
Cc1nnc2n1-c1sc(CCc3ccc4c(c3)CCO4)cc1C(c1ccccc1Cl)=NC2 CHEMBL287465 IC50 20.0 nM
Cc1nnc2n1-c1sc(CCc3ccc4c(c3)CCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL289463 IC50 20.0 nM
Cc1nnc2n1-c1sc(C#C[Si](C)(C)C)cc1C(c1ccccc1Cl)=NC2 CHEMBL32475 IC50 20.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL20033 IC50 20.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccccc1F)=NC2 CHEMBL279664 IC50 20.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1ccc(Br)cc1 CHEMBL2113723 IC50 21.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl CHEMBL53019 IC50 21.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1cccc(Br)c1 CHEMBL2113722 IC50 22.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)NC(C)(C)C)C1c1ccccc1Cl CHEMBL105908 IC50 22.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1ccccc1Br CHEMBL2113721 IC50 23.0 nM
CCCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)sc2cc(OC)ccc12 CHEMBL97176 IC50 24.0 nM
COc1ccc([C@@H]2CC[C@@H](OCCCn3c(C)nc4cnccc43)O2)cc1OC CHEMBL34361 IC50 25.0 nM
O=C(/C=C/C=C(c1cccc(Cl)c1)c1cccc(Cl)c1)NCCCCc1cccnc1 CHEMBL53149 IC50 25.0 nM
COc1ccc(/C(C)=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)cc1 CHEMBL52966 IC50 25.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCS(=O)(=O)c1ccccc1Br CHEMBL2113733 IC50 25.0 nM
COc1cccc(/C(=C\C=C\C(=O)NCCCCc2cccnc2)c2cccc(F)c2)c1 CHEMBL294387 IC50 25.0 nM
COc1ccc(C(=C/C=C/C(=O)NCCCCc2cccnc2)c2ccc(OC)cc2)cc1 CHEMBL54029 IC50 25.0 nM
CCCOc1c(NC(=O)N(O)C(C)CC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL160290 IC50 25.0 nM
COc1cc2c(cc1OC)C(=O)N(CC#Cc1cc3c(s1)-n1c(C)nnc1CN=C3c1ccccc1Cl)CC2 CHEMBL20691 IC50 25.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc43)cc1C(c1ccccc1Cl)=NC2O CHEMBL282495 IC50 25.0 nM
Cc1nnc2n1-c1sc(C#CCn3c4ccccc4c(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL278635 IC50 25.0 nM
CCCOc1c(NC(=O)N(O)C(C)(C)C)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL155851 IC50 26.0 nM
CCCCCc1c(/C=C/C(=O)N[C@@H](CC)CCCc2cccnc2)n(C)c2cc(OC)ccc12 CHEMBL319384 IC50 26.0 nM
C[C@@H]1C(=O)O[C@H]2[C@H](OCc3ccc(Cl)cc3)C34[C@H]5C[C@@H](C(C)(C)C)[C@]36[C@@H](OC(=O)[C@@H]6O)O[C@@]4(C(=O)O5)[C@@]12O CHEMBL2304168 IC50 28.9 nM
COc1ccc(/C=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)cc1 CHEMBL51760 IC50 30.0 nM
CC/C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL299856 IC50 30.0 nM
COc1ccc(C(=C/C=C/C(=O)NC(C)CCCc2cccnc2C)c2ccc(OC)cc2)cc1 CHEMBL54046 IC50 30.0 nM
CCCOc1c(NC(=O)NO)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL160218 IC50 30.0 nM
Cc1nnc2n1-c1sc(CCc3ccc(CC(C)C)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL32942 IC50 30.0 nM
COc1ccc(C2=C(/C=C/C(=O)N[C@@H](C)CCCc3cccnc3)CCc3cc(OC)ccc32)cc1 CHEMBL98401 IC50 30.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4cc(Cl)ccc4c4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL279893 IC50 30.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)n(CCN(C)C)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20293 IC50 30.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCC CHEMBL59051 IC50 33.0 nM
CCCCN(O)C(=O)Nc1cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCC CHEMBL346538 IC50 33.0 nM
CCCCCC1=C(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)Cc2cc(OC)ccc21 CHEMBL97120 IC50 33.0 nM
COc1cccc(C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)c2cccc(OC)c2)c1 CHEMBL301797 IC50 35.0 nM
Cc1nnc2n1-c1sc(CCc3ccc(C4CCCCC4)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL432850 IC50 35.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCS(=O)(=O)c1ccc(Br)cc1 CHEMBL2113726 IC50 38.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1ccc(OC)cc1 CHEMBL2113730 IC50 39.0 nM
CCCCC/C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL277245 IC50 40.0 nM
COc1ccccc1C(=C/C=C/C(=O)NCCCCc1cccnc1)c1ccccc1OC CHEMBL53804 IC50 40.0 nM
COc1ccc(/C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)C(C)C)cc1 CHEMBL300299 IC50 40.0 nM
O=C(/C=C/C=C(c1ccc(F)cc1)c1ccc(F)cc1)NCCCCc1cccnc1 CHEMBL415940 IC50 40.0 nM
COc1cccc(/C(=C/C=C/C(=O)NCCCCc2cccnc2)c2cccc(F)c2)c1 CHEMBL52971 IC50 40.0 nM
COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NCCCN34)cc2)cc(OC)c1OC CHEMBL106521 IC50 40.0 nM
CCCCC/C(=C\C=C\C(=O)N[C@@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL95720 IC50 40.0 nM
CCCCCc1c(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)oc2cc(OC)ccc12 CHEMBL95765 IC50 40.0 nM
COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NCCN34)cc2)cc(OC)c1OC CHEMBL449395 IC50 40.0 nM
CC1C(=O)O[C@H]2[C@H](O)C34[C@H]5C[C@@H](C(C)(C)C)[C@]36[C@@H](OC(=O)[C@@H]6OCOCc3ccccc3)O[C@@]4(C(=O)O5)[C@@]12O CHEMBL2304167 IC50 40.4 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1ccc(Cl)c(Cl)c1 CHEMBL2113724 IC50 45.0 nM
Cc1nnc2n1-c1ccc(C#CCCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)=NC2 CHEMBL19991 IC50 45.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3ccncc32)=NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl CHEMBL320241 IC50 49.0 nM
COc1ccc(C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)c2ccc(OC)c(OC)c2)cc1OC CHEMBL53372 IC50 50.0 nM
CCC/C(=C\C=C\C(=O)N[C@H](C)CCCc1cccnc1)c1ccc(OC)cc1 CHEMBL51855 IC50 50.0 nM
C[C@H](CCCc1cccnc1)NC(=O)c1ccc(-c2ccccc2)c(-c2ccccc2)c1 CHEMBL299760 IC50 50.0 nM
CCCc1cc(C(=O)N[C@H](C)CCCc2cccnc2)ccc1-c1ccc(OC)c(OC)c1 CHEMBL432324 IC50 50.0 nM
COc1cc(CCc2ccc(C3=Cc4oc(C)cc4C4=NCCN34)cc2)cc(OC)c1OC CHEMBL319921 IC50 50.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccccc1F)=NC2O CHEMBL279021 IC50 50.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc4c3=O)cc1C(c1ccccc1Cl)=NC2 CHEMBL283790 IC50 51.0 nM
O=C(C/C=C/C=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1 CHEMBL52297 IC50 55.0 nM
COc1ccc(C(=C/C=C/C(=O)NCCCCc2cccnc2)c2ccc(OC)c(OC)c2)cc1OC CHEMBL300251 IC50 55.0 nM
COc1ccc(-c2c(/C=C/C(=O)N[C@@H](C)CCCc3cccnc3)ccc3cc(OC)ccc23)cc1 CHEMBL319568 IC50 55.0 nM
CCCOc1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(N(CC)C(=O)N(O)CCC)c1OCCC CHEMBL155760 IC50 56.0 nM
CCCOc1c(NC(=O)N(O)C(C)C)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL155873 IC50 58.0 nM
C[C@@H]1C(=O)O[C@H]2[C@H](OCOCc3ccccc3)C34[C@H]5C[C@@H](C(C)(C)C)[C@]36[C@@H](OC(=O)[C@@H]6O)O[C@@]4(C(=O)O5)[C@@]12O CHEMBL2304166 IC50 58.8 nM
CCCOc1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(N(O)C(=O)NCC)c1OCCC CHEMBL160839 IC50 59.0 nM
CCCOc1c(OC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CCO CHEMBL109738 Ki 59.0 nM
O=C(/C=C/C=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1)NCCCCc1cccnc1 CHEMBL52615 IC50 60.0 nM
COc1ccc(C(=C/C=C/C(=O)N[C@@H](CCCc2cccnc2)C2CC2)c2ccc(OC)cc2)cc1 CHEMBL53029 IC50 60.0 nM
Cc1ccc(C(=C/C=C/C(=O)NCCCCc2cccnc2)c2ccc(C)cc2)cc1 CHEMBL55156 IC50 60.0 nM
COc1ccc(-c2ccc(C(S)=N[C@H](C)CCCc3cccnc3)cc2)cc1OC CHEMBL54041 IC50 60.0 nM
COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NC(C)(C)CN34)cc2)cc(OC)c1OC CHEMBL104767 IC50 60.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccc(-c4ccccn4)s3)cc1C(c1ccccc1Cl)=NC2 CHEMBL284079 IC50 60.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc3ccccc32)=NC(C)=C(C(=O)NC(C)(C)C)[C@@H]1c1ccccc1Cl CHEMBL432393 IC50 60.0 nM
COc1ccc(C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)c2ccc(OC)cc2)cc1 CHEMBL52577 IC50 65.0 nM
CCCOc1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(N(CC)C(=O)N(C)O)c1OCCC CHEMBL434090 IC50 68.0 nM
Cc1nnc2n1-c1sc(C#CCn3c4c(c5cc(Cl)ccc53)CCCCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL20927 IC50 70.0 nM
O=c1c2ccccc2c2ccccc2n1CC#Cc1cc2c(s1)-n1c(CO)nnc1CN=C2c1ccccc1Cl CHEMBL19917 IC50 75.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1cc([N+](=O)[O-])ccc1Cl)=NC2 CHEMBL21026 IC50 75.0 nM
C=CCc1cc(C(=O)N[C@H](C)CCCc2cccnc2)ccc1-c1ccc(OC)c(OC)c1 CHEMBL296169 IC50 80.0 nM
Cc1nnc2n1-c1sc(/C=C\c3ccc(CC(C)C)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL286229 IC50 80.0 nM
Cc1nnc2n1-c1sc(C#CCN3C(=O)CCc4ccccc43)cc1C(C1=CC(=O)CC=C1Cl)=NC2 CHEMBL281780 IC50 80.0 nM
COc1ccc(C(=C/C=C/C(=O)NC(C)(C)CCCc2cccnc2)c2ccc(OC)cc2)cc1 CHEMBL57510 IC50 85.0 nM
CCCCC1=C(/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)CCc2cc(OC)ccc21 CHEMBL328833 IC50 90.0 nM
Cc1nnc2n1-c1sc(C#CCn3c4c(c5cc(Cl)ccc53)CCCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL20690 IC50 90.0 nM
CCCNC(=O)N(O)c1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OCCC)c1OCCC CHEMBL160571 IC50 91.0 nM
COc1cc([C@@H]2CC[C@H](OCCCc3cccnc3)O2)cc(OC)c1OC CHEMBL36269 IC50 100.0 nM
CCCCCC(=C/C=C/C(=O)N[C@H](C)CCCc1cccnc1)CCCCC CHEMBL300463 IC50 100.0 nM
O=C(CCC=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1 CHEMBL52821 IC50 100.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccc(CC(C)C)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL33139 IC50 100.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccccc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL288098 IC50 100.0 nM
Cc1nnc2n1-c1sc(CCc3ccc(-n4ccnc4)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL369194 IC50 100.0 nM
Cc1cc2nc3ccc(C(=O)NCCCCc4cncnc4)cn3c(=O)c2cc1C CHEMBL143914 IC50 100.0 nM
COC1N=C(c2ccccc2F)c2cc(C#CCN3C(=O)CCc4ccccc43)ccc2-n2c(C)nnc21 CHEMBL20141 IC50 100.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccc(Cl)cc1)=NC2 CHEMBL20591 IC50 100.0 nM
COc1cc([C@H]2CC[C@@H](OCCCc3cccnc3)O2)cc(OC)c1OC CHEMBL37809 IC50 100.0 nM
CCc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)=NC2 CHEMBL283152 IC50 100.0 nM
COc1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OC CHEMBL297624 Ki 103.0 nM
CCCOc1c(OCCCOP(=O)([O-])O)cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O CHEMBL325491 Ki 110.0 nM
Cc1nnc2n1-c1sc(/C=C\c3ccc4c(c3)CCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL286762 IC50 110.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)NC2 CHEMBL281139 IC50 110.0 nM
O=C(/C=C/C=C(c1cccc([N+](=O)[O-])c1)c1cccc([N+](=O)[O-])c1)NCCCCc1cccnc1 CHEMBL52970 IC50 115.0 nM
CCCCCCCC1CCC(OCCCn2c(C)nc3cnccc32)O1 CHEMBL34612 IC50 120.0 nM
CC[C@H](CCCc1cccnc1)NC(=O)/C=C/C=C(c1ccc(OC)cc1)c1ccc(OC)cc1 CHEMBL54482 IC50 120.0 nM
Cc1nnc2n1-c1sc(/C=C\c3ccc(C4CCCCC4)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL32389 IC50 120.0 nM
Cc1nnc2n1-c1sc(C#CCn3c4ccccc4c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL20701 IC50 120.0 nM
Cc1nnc2n1-c1sc(I)cc1C(c1ccccc1Cl)=NC2C CHEMBL283113 IC50 120.0 nM
COc1ccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2-c2ccc(OC)cc2)cc1 CHEMBL50250 IC50 125.0 nM
C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@]36[C@@H](OC(=O)[C@@H]6O)O[C@@]4(C(=O)O5)[C@@]12O CHEMBL514432 IC50 128.0 nM
Cc1nnc2n1-c1ccc(C#CCOc3cccnc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL20344 IC50 130.0 nM
COc1ccc(-c2ccc(C(S)=NCCCCc3cccnc3)cc2)cc1OC CHEMBL300644 IC50 140.0 nM
COc1ccc([C@@H]2CC[C@H](OCCCc3cccnc3)O2)cc1OC CHEMBL286197 IC50 150.0 nM
Cc1nnc2n1-c1sc(C#Cc3cccc4ccccc34)cc1C(c1ccccc1Cl)=NC2 CHEMBL32110 IC50 150.0 nM
COc1ccc([C@H]2CC[C@@H](OCCCc3cccnc3)O2)cc1OC CHEMBL37951 IC50 150.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)n(CCN(C)C)c(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 CHEMBL19721 IC50 150.0 nM
CCCCN(O)C(=O)NCc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCSc1ccc(Cl)cc1 CHEMBL2113731 IC50 167.0 nM
C[C@H](CCCc1cccnc1)NC(=O)/C=C/C=C(c1cccc(F)c1)c1cccc(F)c1 CHEMBL54935 IC50 170.0 nM
COc1ccc(-c2ccc(C(=O)N[C@H](C)CCCc3cccnc3)cc2Br)cc1OC CHEMBL53750 IC50 180.0 nM
Cc1nnc2n1-c1sc(C#CCO)cc1C(c1ccccc1Cl)=NC2 CHEMBL32327 IC50 180.0 nM
Cc1nnc2n1-c1sc(/C=C\C(=O)N3CCOCC3)cc1C(c1ccccc1Cl)=NC2 CHEMBL286557 IC50 180.0 nM
COc1cc(C2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OC CHEMBL291332 IC50 180.0 nM
CCO/C(O)=C1\C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)OC)[C@@H]1c1ccccc1Cl CHEMBL105029 IC50 183.0 nM
Cc1nc2cnccc2n1CCCOC1CCC(c2ccccc2)O1 CHEMBL36154 IC50 190.0 nM
COc1ccc(C(=C/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)c2ccc(OC)cc2)cc1 CHEMBL50244 IC50 200.0 nM
COc1ccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2[N+](=O)[O-])cc1OC CHEMBL53534 IC50 200.0 nM
COc1ccc(-c2ccc(C(=O)N[C@H](C)CCCc3cccnc3)cc2[N+](=O)[O-])cc1OC CHEMBL53482 IC50 200.0 nM
Cc1ccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2)cc1C CHEMBL51867 IC50 200.0 nM
COc1cccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2-c2cccc(OC)c2)c1 CHEMBL53808 IC50 200.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCCCc4cncnc4)cn3c(=O)c2c1 CHEMBL141825 IC50 200.0 nM
Clc1ccc([C@H]2CC[C@@H](OCCCc3cccnc3)O2)cc1Cl CHEMBL288849 IC50 200.0 nM
O=C1CCc2ccccc2N1CC#Cc1ccc2c(c1)C(c1ccccc1F)=NCc1nnc(C(F)(F)F)n1-2 CHEMBL279084 IC50 200.0 nM
COc1ccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2Br)cc1OC CHEMBL52636 IC50 220.0 nM
COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NC(C)CN34)cc2)cc(OC)c1OC CHEMBL320609 IC50 220.0 nM
Fc1ccc([C@H]2CC[C@@H](OCCCc3cccnc3)O2)cc1 CHEMBL284078 IC50 230.0 nM
COc1ccc(C2CCC(OCCCn3c(C)nnc3C)O2)cc1OC CHEMBL286696 IC50 250.0 nM
COc1ccc(C(=C/C=C/C(=O)NCCOCc2cccnc2)c2ccc(OC)cc2)cc1 CHEMBL54068 IC50 250.0 nM
C[C@@H](CCCc1cccnc1)NC(=O)/C=C/C=C(c1cccc(F)c1)c1cccc(F)c1 CHEMBL52933 IC50 250.0 nM
Cc1ccc(C(=C/C=C/C(=O)N[C@H](C)CCCc2cccnc2)c2ccc(C)cc2)cc1 CHEMBL446140 IC50 250.0 nM
COc1ccc(C(=C/C=C/C(=O)Nc2ccc(Cc3cccnc3)cc2)c2ccc(OC)cc2)cc1 CHEMBL54106 IC50 250.0 nM
C[C@H](CCCc1cccnc1)NC(=O)/C=C/C=C(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL300742 IC50 250.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccccn3)cc1C(c1ccccc1Cl)=NC2 CHEMBL285035 IC50 250.0 nM
Cc1cc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2cc1C CHEMBL56588 IC50 250.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc43)cc1C(c1ccccc1Cl)=NC2C CHEMBL20178 IC50 250.0 nM
CC(CCCc1cccnc1)NC(=O)c1ccc2nc3ccc(C(C)C)cc3c(=O)n2c1 CHEMBL57825 IC50 250.0 nM
Cc1nnc2n1-c1sc(C#CC(=O)N3CCOCC3)cc1C(c1ccccc1Cl)=NC2 CHEMBL287380 IC50 260.0 nM
C[C@@H](CCCc1cccnc1)NC(=O)/C=C/C=C(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL299780 IC50 275.0 nM
CCCOc1c(NC(=O)N(O)C2CCCCC2)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL155975 IC50 278.0 nM
COc1cccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2)c1 CHEMBL412441 IC50 280.0 nM
CCCCN(O)C(=O)Nc1cc([C@@H]2CC[C@@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(OC)c1OCCS(=O)(=O)c1c(F)c(F)cc(F)c1F CHEMBL2113732 IC50 285.0 nM
Cc1nc2ccccc2n1Cc1ccc(S(=O)(=O)N(C)C2CCCCC2)cc1 CHEMBL418608 IC50 300.0 nM
COc1cccc(C(=C/C=C/C(=O)N[C@@H](C)CCCc2cccnc2)c2cccc(OC)c2)c1 CHEMBL431923 IC50 300.0 nM
COc1ccc(C(=C/C=C/C(=O)NCCCOc2cccnc2)c2ccc(OC)cc2)cc1 CHEMBL54163 IC50 300.0 nM
COc1ccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2OC)cc1OC CHEMBL52031 IC50 300.0 nM
O=C(NCCCCc1cccnc1)c1ccc(-c2cccc(O)c2)cc1 CHEMBL416480 IC50 300.0 nM
Cc1nnc2n1-c1sc(Br)cc1C(c1ccccc1Cl)=NC2 CHEMBL32479 IC50 300.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccc(C4CCCCC4)cc3)cc1C(c1ccccc1Cl)=NC2 CHEMBL33857 IC50 300.0 nM
Cc1nnc2nc(-c3ccccc3F)c3cc(C#CCN4C(=O)c5ccccc5C4=O)ccc3n12 CHEMBL20196 IC50 300.0 nM
COc1ccc(C2CCC(OC/C=C/c3cccnc3)O2)cc1OC CHEMBL37952 IC50 300.0 nM
COc1ccc(C2CCC(OCCCc3cccnc3)O2)cc1OC CHEMBL284773 IC50 300.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL57736 IC50 350.0 nM
Cc1nnc2n1-c1sc(I)cc1C(c1cc([N+](=O)[O-])ccc1Cl)=NC2 CHEMBL20808 IC50 360.0 nM
Cc1nnc2n1-c1sc(I)cc1C(c1ccccc1Cl)=NC2 CHEMBL20359 IC50 370.0 nM
COc1ccc2c(=O)n3cc(C(=O)NCCCCc4cccnc4)ccc3nc2c1 CHEMBL56418 IC50 370.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccc4c(c3)CCC4)cc1C(c1ccccc1Cl)=NC2 CHEMBL284280 IC50 380.0 nM
O=C(/C=C\C=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1 CHEMBL51696 IC50 400.0 nM
CC[C@@H](CCCc1cccnc1)NC(=O)/C=C/C=C(c1ccc(OC)cc1)c1ccc(OC)cc1 CHEMBL52924 IC50 400.0 nM
COc1ccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2)cc1OC CHEMBL51170 IC50 400.0 nM
Cc1nnc2n1-c1sc(/C=C\c3ccccn3)cc1C(c1ccccc1Cl)=NC2 CHEMBL285926 IC50 400.0 nM
Cc1cc(CCc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc2c1OC(C)(C)C2 CHEMBL286337 IC50 400.0 nM
Cc1cc(C#Cc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc2c1OC(C)(C)C2 CHEMBL32932 IC50 400.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL417781 IC50 400.0 nM
CC(C)c1ccc2nc3ccc(C(=O)N[C@@H](C)CCCc4cccnc4)cn3c(=O)c2c1 CHEMBL142903 IC50 400.0 nM
COC(=O)C1=C(c2ccc(-n3ccnc3)cc2)NC(C)=C(C(=O)Nc2nccs2)C1c1ccccc1Cl CHEMBL104620 IC50 415.0 nM
Cc1nnc2n1-c1sc(/C(CC(=O)N3CCOCC3)=N\N)cc1C(c1ccccc1Cl)=NC2 CHEMBL285199 IC50 420.0 nM
Cc1nnc2n1-c1sc(C#Cc3ccc4c(c3)CCO4)cc1C(c1ccccc1Cl)=NC2 CHEMBL34796 IC50 420.0 nM
CCCOc1c(NC(=O)N(O)Cc2ccccc2)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC CHEMBL160148 IC50 423.0 nM
O=C(C=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1 CHEMBL54709 IC50 450.0 nM
Cc1nnc2n1-c1sc(/C=C/C(=O)N3CCOCC3)cc1C(c1ccccc1Cl)=NC2 CHEMBL285067 IC50 450.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4cncnc4)cn3c(=O)c2c1 CHEMBL294706 IC50 450.0 nM
COc1ccc(C2CCC(OCCCCn3c(C)nc4cnccc43)O2)cc1OC CHEMBL37770 IC50 500.0 nM
COc1ccc(C2CCC(COCCn3c(C)nc4cnccc43)O2)cc1OC CHEMBL34669 IC50 500.0 nM
Cc1nc2ccccc2n1Cc1ccc(C(=O)N(C)C2CCCCC2)cc1 CHEMBL345902 IC50 500.0 nM
Cc1cccc(-c2ccc(C(=O)NCCCCc3cccnc3)cc2)c1 CHEMBL54095 IC50 500.0 nM
COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NCC(C)(C)CN34)cc2)cc(OC)c1OC CHEMBL104631 IC50 500.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)OC2 CHEMBL282666 IC50 500.0 nM
Cc1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL300338 IC50 500.0 nM
O=C(CCCCC=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1 CHEMBL52693 IC50 550.0 nM
Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c4ccccc43)cc1C(c1ccccc1Cl)NC2=O CHEMBL279476 IC50 560.0 nM
C/C1=C\CC[C@@]2(C)O[C@@H]2[C@@]2(O)OCC3=C2CC[C@@H](C)[C@]3(C)CC1 CHEMBL371569 Log IC50 575.44 nM
C/C1=C\CC[C@]2(C)O[C@H]2[C@@]2(O)OCC3=C2CC[C@@H](C)[C@]3(C)CC1 CHEMBL191612 Log IC50 575.44 nM
CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCC[n+]1ccsc1)OC CHEMBL295212 IC50 600.0 nM
CC(C)c1ccc2nc3ccc(C(=O)N[C@H](C)CCCc4cccnc4)cn3c(=O)c2c1 CHEMBL142433 IC50 600.0 nM
CC(C)Oc1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL57716 IC50 600.0 nM
CC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 CHEMBL10971 IC50 610.0 nM
O=C(NCCCCc1cccnc1)c1ccc(-c2ccccc2)cc1 CHEMBL416120 IC50 630.0 nM
CCCCc1ccc(C#Cc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)cc1 CHEMBL32767 IC50 650.0 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC2)C[C@@H](C(=O)N1CCOCC1)C3 CHEMBL5303510 KD 660.0 nM
CC(=O)N1CCC(=C2c3ccc(F)cc3CCc3cccnc32)CC1 CHEMBL344942 IC50 670.0 nM
COc1ccc(C(=C/C=C/C(=O)NC(C)CCCc2ccc(C)nc2)c2ccc(OC)cc2)cc1 CHEMBL52526 IC50 700.0 nM
O=C(NCCCCc1cccnc1)c1ccc(-c2cccc(OC3=CC=CC=CC3)c2)cc1 CHEMBL50050 IC50 700.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3ccc(Br)cc3c(=O)n2c1 CHEMBL58518 IC50 700.0 nM
COc1ccc(C(=C/C=C/C(=O)N[C@@H](CCCc2cccnc2)C(C)C)c2ccc(OC)cc2)cc1 CHEMBL297734 IC50 800.0 nM
Brc1ccc([C@H]2CC[C@@H](OCCCc3cccnc3)O2)cc1 CHEMBL37547 IC50 800.0 nM
CC(=O)N1CCC(=C2c3ccc(Br)cc3CCc3cccnc32)CC1 CHEMBL142268 IC50 810.0 nM
CC(=O)N1CCC(=C2c3cc(F)ccc3CCc3cccnc32)CC1 CHEMBL143272 IC50 820.0 nM
COc1ccc(C2CCC(OCc3ccc(-n4c(C)nc5ccccc54)cc3)O2)cc1OC CHEMBL37602 IC50 900.0 nM
CC(C)(C)c1ccc(C2=Cc3ccccc3C3=NCCN23)cc1 CHEMBL79089 IC50 900.0 nM
COc1ccc([C@H]2O[C@@H](c3ccc(OC)c(OC)c3)[C@H](C)[C@H]2C)cc1OC CHEMBL112481 Ki 1000.0 nM
CC(=O)N1CCC(=C2c3ccc(C)cc3CCc3cccnc32)CC1 CHEMBL143242 IC50 1000.0 nM
CC(=O)N1CCC(=C2c3cc(F)c(F)cc3CCc3cccnc32)CC1 CHEMBL342747 IC50 1000.0 nM
Cc1nnc2n1-c1sc(-c3[nH]nnc3C(=O)N3CCOCC3)cc1C(c1ccccc1Cl)=NC2 CHEMBL33217 IC50 1000.0 nM
Cc1nnc2n1-c1sc(-c3cc(O)[nH]n3)cc1C(c1ccccc1Cl)=NC2 CHEMBL32303 IC50 1000.0 nM
COc1ccc([C@H]2CC[C@@H](OCCCc3ccc[n+](C)c3)O2)cc1OC CHEMBL287821 IC50 1000.0 nM
Clc1ccc([C@H]2CC[C@@H](OCCCc3cccnc3)O2)cc1 CHEMBL37603 IC50 1000.0 nM
COc1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL293362 IC50 1000.0 nM
O=C1CCc2ccccc2N1CC#Cc1ccc2c(c1)C(c1ccc(Cl)cc1)=NCc1nnc(C(F)(F)F)n1-2 CHEMBL283365 IC50 1000.0 nM
Cc1nnc2n1-c1ccc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccccc1F)=N[C@@H]2C CHEMBL280207 IC50 1000.0 nM
Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1Cl)=NC2 CHEMBL20914 IC50 1000.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3cc(Cl)ccc3c(=O)n2c1 CHEMBL57489 IC50 1000.0 nM
Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1F)=NC2 CHEMBL20577 IC50 1000.0 nM
O=C1c2ccccc2C(=O)N1CC#Cc1ccc2c(c1)C(c1ccccc1F)=NCc1nncn1-2 CHEMBL20325 IC50 1000.0 nM
Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1F)NC2 CHEMBL418370 IC50 1000.0 nM