O=C(O)Cc1cnc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cccc(F)c1 CHEMBL1088284 IC50 0.012 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1Oc1ncc(S(C)(=O)=O)cc1Br CHEMBL2181748 IC50 0.02 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL589973 Kb 0.05 nM
O=C(O)Cc1sc(N(c2ccccc2)c2ccccc2)nc1-c1ccc(Cl)cc1 CHEMBL1081033 IC50 0.072 nM
O=C(O)Cc1sc(N(c2ccccc2)c2ccccc2)nc1-c1cccc(F)c1 CHEMBL1087029 IC50 0.079 nM
CCCc1cc(-c2ccc(Oc3ccc(CC(=O)O)cc3OC)c(NS(=O)(=O)c3ccc(Cl)cc3Cl)c2)n[nH]1 CHEMBL1950879 Kb 0.084 nM
CC(c1ccccc1)(c1ccccc1)c1nc(-c2ccc(F)cc2)c(CC(=O)O)s1 CHEMBL1087622 IC50 0.085 nM
O=C(O)Cc1sc(N(c2ccccc2)c2ccccc2)nc1-c1ccc(F)cc1 CHEMBL1080695 IC50 0.098 nM
CN(c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c(Cl)c1)S(C)(=O)=O CHEMBL1778632 IC50 0.1 nM
COc1ccc2[nH]c(C(=O)Nc3ccc(Cn4nc(C)c(CC(=O)O)c4C)cc3)c(C)c2c1 CHEMBL3639847 Ki 0.1 nM
CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc2ccc(F)cc21 CHEMBL3690164 Ki 0.1 nM
CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc2ccc(F)cc21 CHEMBL3690165 Ki 0.1 nM
CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2ccc(F)cc21 CHEMBL3690177 Ki 0.1 nM
CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2ccc(F)cc21 CHEMBL3690178 Ki 0.1 nM
COc1ccc2oc(C(=O)Nc3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)c(C)c2c1 CHEMBL3690185 Ki 0.1 nM
CCCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2cc(F)ccc21 CHEMBL3690191 Ki 0.1 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685926 Ki 0.1 nM
CCc1c(CC(=O)O)c(C2CC2)nn1Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 CHEMBL2181751 Ki 0.1 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(C2CC2)c1CC(=O)O CHEMBL3685933 Ki 0.1 nM
CCc1nn(Cc2ccc(NC(=O)OCc3ccc(Cl)c(Cl)c3)cc2)c(CC)c1CC(=O)O CHEMBL3685949 Ki 0.1 nM
CCc1nn(Cc2ccc(NC(=O)OCc3ccc4ccccc4c3)cc2)c(CC)c1CC(=O)O CHEMBL3685952 Ki 0.1 nM
CCc1nn(C(C)c2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(CC)c1CC(=O)O CHEMBL3686053 Ki 0.1 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(NS(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1 CHEMBL3667662 IC50 0.1 nM
CCc1nn(Cc2ccc(-c3nc4cc5ccccc5cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3947507 Ki 0.1 nM
CCc1nn(Cc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3977228 Ki 0.1 nM
CCC(=O)Nc1ccc(Oc2cc(CC(=O)O)ccc2OC)c(C(=O)N[C@@H](C)c2ccccc2)c1 CHEMBL1933918 Kb 0.13 nM
CCCc1nc(-c2ccc(Oc3ccc(CC(=O)O)cc3OC)c(NS(=O)(=O)c3ccc(Cl)cc3Cl)c2)c[nH]1 CHEMBL1950878 Kb 0.18 nM
O=C(O)COc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cccc(F)c1 CHEMBL1086856 IC50 0.2 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c(Cl)c1 CHEMBL1778637 IC50 0.2 nM
Cc1ccc(C#N)cc1-c1cc(C(F)(F)F)ccc1OCC(=O)O CHEMBL1777822 IC50 0.2 nM
N#Cc1ccc(F)c(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c1 CHEMBL1778635 IC50 0.2 nM
CC(C)(C)NC(=O)c1ccc(Oc2cc(F)c(CC(=O)O)cc2Cl)c(NS(=O)(=O)c2ccc(C3CC3)cc2Cl)c1 CHEMBL1951575 Kb 0.2 nM
Cc1c(CC(=O)O)c2ccc(F)cn2c1Sc1ccc(S(C)(=O)=O)cc1F CHEMBL2181803 Ki 0.2 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3Cc3ccccc3)cc2F)c(C)c1CC(=O)O CHEMBL3685833 Ki 0.2 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3685840 Ki 0.2 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccc(F)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3685841 Ki 0.2 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4cc(F)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3685842 Ki 0.2 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4cc(Cl)ccc4o3)cc2)c(CC)c1CC(=O)O CHEMBL3690155 Ki 0.2 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3CC)cc2)c(CC)c1CC(=O)O CHEMBL3690158 Ki 0.2 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4ccc(F)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3690161 Ki 0.2 nM
CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2ccccc21 CHEMBL3690167 Ki 0.2 nM
CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2cc(F)ccc21 CHEMBL3690168 Ki 0.2 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccc(Cl)cc4o3)cc2)c(C)c1CC(=O)O CHEMBL3690172 Ki 0.2 nM
CCCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2ccccc21 CHEMBL3690189 Ki 0.2 nM
CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2cc(F)ccc21 CHEMBL3690190 Ki 0.2 nM
CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2ccccc21 CHEMBL3690192 Ki 0.2 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(C(C)(C)C)cc3)cc2)c(C)c1CC(=O)O CHEMBL3685864 Ki 0.2 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(CC)c1CC(=O)O CHEMBL3685885 Ki 0.2 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(CC)c1CC(=O)O CHEMBL3685891 Ki 0.2 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685924 Ki 0.2 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685925 Ki 0.2 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(C)c1CC(=O)O CHEMBL3685936 Ki 0.2 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1cccc(F)c1 CHEMBL3936579 IC50 0.2 nM
CCc1nn(Cc2ccc(-c3nc4cc(Cl)c(Cl)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3961172 Ki 0.2 nM
CCc1nn(Cc2ccc(-c3nc4ccc(C(F)(F)F)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3974100 Ki 0.2 nM
CCc1nn(Cc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3903436 Ki 0.2 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3cc(F)ccc31)CC2 CHEMBL3904070 IC50 0.2 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccc1C(F)(F)F)CC2 CHEMBL3943674 IC50 0.22 nM
Cc1noc(-c2ccccc2)c1CN1CC2(CC1=O)C(=O)N(CC(=O)O)c1ccc(Cl)cc12 CHEMBL259940 IC50 0.23 nM
C[C@@H](NC(=O)c1ccc2c(=O)n(-c3ccc(F)cc3)c(CCCCC(=O)O)cc2c1)c1ccc(F)cc1 CHEMBL3965034 Ki 0.23 nM
O=C(O)Cc1sc(N(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccc(F)cc1 CHEMBL1087030 IC50 0.24 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(CC)c1CC(=O)O CHEMBL3685890 Ki 0.25 nM
COc1ccc(N(c2ccc(OC)cc2)c2nc(-c3cccc(F)c3)c(CC(=O)O)s2)cc1 CHEMBL1087031 IC50 0.26 nM
CCNC(=O)c1ccc(Oc2c(OC)cc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL570653 Kb 0.26 nM
O=C(O)Cc1ccc(OCC2CC2)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3959123 IC50 0.28 nM
CCCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3948483 IC50 0.28 nM
C[C@H]1CN(Cc2cc(C(F)(F)F)ccc2OCC(=O)O)CCN1C(=O)Cc1ccc(F)cc1 CHEMBL1689131 IC50 0.3 nM
CCS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c(Cl)c1 CHEMBL1778638 IC50 0.3 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4cc(Cl)ccc4o3)cc2)c(C)c1CC(=O)O CHEMBL3685838 Ki 0.3 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4s3)cc2)c(C)c1CC(=O)O CHEMBL3685844 Ki 0.3 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3690156 Ki 0.3 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3C)cc2)c(CC)c1CC(=O)O CHEMBL3690157 Ki 0.3 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4cc(F)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3690159 Ki 0.3 nM
CCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)oc2c(F)cccc12 CHEMBL3690170 Ki 0.3 nM
CCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)oc2c(F)cc(F)cc12 CHEMBL3690171 Ki 0.3 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4ccc(Cl)cc4c3C)cc2F)c(C)c1CC(=O)O CHEMBL3690180 Ki 0.3 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4cc(Br)ccc4c3C)cc2F)c(C)c1CC(=O)O CHEMBL3690181 Ki 0.3 nM
CCc1nn(Cc2ccc(NC(=O)OCc3ccccc3)cc2)c(CC)c1CC(=O)O CHEMBL3685943 Ki 0.3 nM
Cc1cc(NC(=O)c2ccc3ccccc3c2)ccc1Cn1nc(C)c(CC(=O)O)c1C CHEMBL3685967 Ki 0.3 nM
Cc1ccccc1S(=O)(=O)c1ccc(-c2c(C)c(CC(=O)O)cc3ccc(F)cc23)cc1 CHEMBL3667608 IC50 0.3 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1cc(F)ccc1Cl CHEMBL3940607 IC50 0.3 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1c(F)cccc1F CHEMBL3903658 IC50 0.3 nM
Cc1nn(Cc2ccc(-c3cc4ccc(C(F)(F)F)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3918166 Ki 0.3 nM
CCc1nn(Cc2ccc(-c3nc4cc(Br)c(Cl)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3978108 Ki 0.3 nM
CCc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3920034 Ki 0.3 nM
CCc1nn(Cc2ccc(-c3nc4cc(C)c(Cl)cc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3950956 Ki 0.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc31)CC2 CHEMBL3936792 IC50 0.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccc(F)cc1)CC2 CHEMBL3898097 IC50 0.3 nM
Cc1cc(N(C)S(C)(=O)=O)ccc1-c1cc(C(F)(F)F)ccc1OCC(=O)O CHEMBL1778633 IC50 0.4 nM
CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc2ccccc21 CHEMBL3685846 Ki 0.4 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccc(Cl)cc4o3)cc2F)c(C)c1CC(=O)O CHEMBL3690175 Ki 0.4 nM
CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2c(F)cccc21 CHEMBL3690176 Ki 0.4 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4c(F)cccc4c3C)cc2F)c(C)c1CC(=O)O CHEMBL3690186 Ki 0.4 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4cc(F)ccc4n3C)cc2F)c(C)c1CC(=O)O CHEMBL3690187 Ki 0.4 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685921 Ki 0.4 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)NCc2ccccc2)cc1 CHEMBL3667653 IC50 0.4 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1ccc(F)cc1F CHEMBL3960425 IC50 0.4 nM
CC(C)CCOC(=O)N1CCc2ncsc2[C@H]1c1cc(Cl)ccc1OCC(=O)O CHEMBL3918066 IC50 0.4 nM
CCc1nn(Cc2ccc(-c3nc4cc(F)c(Cl)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3902113 Ki 0.4 nM
CCc1nn(Cc2ccc(-c3nc4c(Cl)cc(Cl)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3945777 Ki 0.4 nM
CCc1nn(Cc2ccc(-c3nc4cc(Br)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3978199 Ki 0.4 nM
Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F CHEMBL3137332 IC50 0.4 nM
O=C(O)CCCCc1cc2cc(C(=O)N[C@@H]3CCCc4ccccc43)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL3934638 Ki 0.4 nM
N#Cc1ccc(N(c2ccccc2)c2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 CHEMBL1087500 IC50 0.46 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1cn(C)c3ccccc13)CC2 CHEMBL3892479 IC50 0.46 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccnc(F)c1 CHEMBL600845 IC50 0.48 nM
COCCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3892136 IC50 0.49 nM
C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc1ccc(Cl)cc1 CHEMBL1689128 IC50 0.5 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685832 Ki 0.5 nM
CCc1nn(Cc2ccc(NC(=O)c3cccc4c3CCCC4)cc2)c(CC)c1CC(=O)O CHEMBL3685898 Ki 0.5 nM
CCc1c(CC(=O)O)c(C)nn1Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 CHEMBL3685935 Ki 0.5 nM
Cc1nn(Cc2ccc(NC(=O)OCc3ccc(Cl)c(Cl)c3)cc2)c(C)c1CC(=O)O CHEMBL3685944 Ki 0.5 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2F)c(CC)c1CC(=O)O CHEMBL3686017 Ki 0.5 nM
CCN(CC)S(=O)(=O)c1ccc(-c2c(C)c(CC(=O)O)cc3ccc(Cl)cc23)cc1 CHEMBL3667639 IC50 0.5 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1cc(Cl)ccc1F CHEMBL3965073 IC50 0.5 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1cccc(F)c1F CHEMBL3939522 IC50 0.5 nM
Cc1nn(Cc2ccc(-c3cc4ccc(C(F)(F)F)cc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3979469 Ki 0.5 nM
Cc1nn(Cc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3958283 Ki 0.5 nM
CCc1nn(Cc2ccc(-c3nc4cc(C)c(Cl)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3953953 Ki 0.5 nM
CCc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3908540 Ki 0.5 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccn1)CC2 CHEMBL3973150 IC50 0.5 nM
O=C(O)Cn1c2c(c3ccccc31)C[C@H](NS(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL194085 Ki 0.51 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccccc1)CC2 CHEMBL3894780 IC50 0.53 nM
CN([C@@H]1CCc2c(c3ccccc3n2CC(=O)O)C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL179036 Ki 0.6 nM
C[C@H]1CN(Cc2cc(Cl)ccc2CC(=O)O)CCN1S(=O)(=O)Cc1ccccc1 CHEMBL1689137 IC50 0.6 nM
C[C@@H](Oc1ccc(C(F)(F)F)cc1-c1cccc(C#N)c1)C(=O)O CHEMBL1778656 IC50 0.6 nM
CCS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2O[C@H](C)C(=O)O)c(Cl)c1 CHEMBL1778655 IC50 0.6 nM
CS(=O)(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)c(Cl)c1 CHEMBL1778642 IC50 0.6 nM
Cc1c(Sc2ccc(Cl)cc2)c2c(-c3cnccn3)cccc2n1CC(=O)O CHEMBL1917440 IC50 0.6 nM
CN(C1CCc2c(c3ccccc3n2CC(=O)O)C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643768 Ki 0.6 nM
COc1ccc2oc(C(=O)Nc3ccc(Cn4nc(C)c(CC(=O)O)c4C)cc3)cc2c1 CHEMBL3685836 Ki 0.6 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4ccc(F)cc4c3C)cc2F)c(C)c1CC(=O)O CHEMBL3690163 Ki 0.6 nM
CCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)oc2c(Cl)cccc12 CHEMBL3690174 Ki 0.6 nM
CCc1c(CC(=O)O)c(C2CC2)nn1Cc1ccc(NC(=O)c2ccc(Cl)cc2C)cc1 CHEMBL3685930 Ki 0.6 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3C)cc2)c(C2CC2)c1CC(=O)O CHEMBL3685932 Ki 0.6 nM
Cc1nn(Cc2ccc(NC(=O)OCc3ccc4ccccc4c3)cc2)c(C)c1CC(=O)O CHEMBL3685947 Ki 0.6 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685977 Ki 0.6 nM
O=C(O)Cc1c2n(c3cc(Cl)ccc13)CC(N(CC1CC1)c1ncc(F)cn1)CC2 CHEMBL3674036 IC50 0.6 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1ccccc1F CHEMBL3909968 IC50 0.6 nM
CCc1nn(Cc2ccc(-c3nc4cc(F)c(Cl)cc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3894091 Ki 0.6 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1COCc3ccccc31)CC2 CHEMBL3897043 IC50 0.6 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccccc1)CC2 CHEMBL3972738 IC50 0.6 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccn1)CC2 CHEMBL3983954 IC50 0.6 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 CHEMBL3920150 IC50 0.6 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(C)n1)CC2 CHEMBL3962450 IC50 0.6 nM
O=C(O)Cn1cc(CCN(Cc2ccccc2)S(=O)(=O)c2ccc(F)cc2)c2ccccc21 CHEMBL398303 Log Ki 0.631 nM
O=C(O)COc1ccc(OC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)[C@@H]2C[C@H]2c2ccccc2)CC3)c1 CHEMBL3952361 IC50 0.67 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCOc1ccc(F)cc1)CC2 CHEMBL3945153 IC50 0.69 nM
CCCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)oc2ccc(F)cc12 CHEMBL3690188 Ki 0.7 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Br)cc3C)cc2)c(CC)c1CC(=O)O CHEMBL3685894 Ki 0.7 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3C)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685920 Ki 0.7 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccccc2Cl)cc1 CHEMBL3667609 IC50 0.7 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2cc(F)cc(F)c2)cc1 CHEMBL3667631 IC50 0.7 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL3667648 IC50 0.7 nM
CN(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3ccc(F)cc3n2C1 CHEMBL3673995 IC50 0.7 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCC1CCCCC1 CHEMBL3926691 IC50 0.7 nM
Cc1nn(Cc2ccc(-c3cc4ccc(C(F)(F)F)cc4[nH]3)cc2C(F)(F)F)c(C)c1CC(=O)O CHEMBL3903702 Ki 0.7 nM
COc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)nc2n1 CHEMBL3946768 Ki 0.7 nM
CCc1nn(Cc2ccc(-c3nc4c(Cl)cc(Cl)cc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3945675 Ki 0.7 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1OCCc3ccccc31)CC2 CHEMBL3911338 IC50 0.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccc(F)cc1)CC2 CHEMBL3893171 IC50 0.7 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)c(CC)c1CC(=O)O CHEMBL3685889 Ki 0.75 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccc1C)CC2 CHEMBL3902741 IC50 0.75 nM
C[C@H]1C[C@@H](N(C(=O)CCC(=O)O)c2ccccc2)c2ccccc2N1C(=O)c1ccccc1 CHEMBL1080199 IC50 0.77 nM
O=C(O)C[C@@H]1CCn2c1c(Sc1ccc(Cl)cc1)c1ccc(F)cc12 CHEMBL370606 Ki 0.8 nM
C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 CHEMBL1689119 IC50 0.8 nM
CN(c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)cc1)S(C)(=O)=O CHEMBL1778627 IC50 0.8 nM
Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3F)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL2204469 IC50 0.8 nM
Cc1c(Cc2ccc(=O)n(Cc3cc(F)c(F)cc3F)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL2204474 IC50 0.8 nM
Cc1c(Cc2ccc(=O)n(Cc3cccc(F)c3F)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236929 IC50 0.8 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3685831 Ki 0.8 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4ccc(F)cc4c3C)cc2)c(C)c1CC(=O)O CHEMBL3685834 Ki 0.8 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4o3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685835 Ki 0.8 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3C)cc2)c(C)c1CC(=O)O CHEMBL3685845 Ki 0.8 nM
CCc1nn(Cc2ccc(NC(=O)c3cc4ccccc4o3)cc2)c(CC)c1CC(=O)O CHEMBL3690162 Ki 0.8 nM
CCc1nn(Cc2ccc(NC(=O)C3[C@H]4C[C@@H]5C[C@@H](C[C@H]3C5)C4)cc2)c(CC)c1CC(=O)O CHEMBL3685910 Ki 0.8 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(-c2ccccc2)c1CC(=O)O CHEMBL3685916 Ki 0.8 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685970 Ki 0.8 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL3667637 IC50 0.8 nM
CN(c1ncc(F)cn1)[C@H]1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674017 IC50 0.8 nM
COCCN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674032 IC50 0.8 nM
Cc1nn(Cc2ccc(-c3cc4ccc(Cl)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3902653 Ki 0.8 nM
Cc1nn(Cc2ccc(-c3cc4ccc(Cl)cc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3912711 Ki 0.8 nM
Cc1nn(Cc2ccc(-c3nc4cc5ccccc5cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3928155 Ki 0.8 nM
CCc1nn(Cc2ccc(-c3nc4c(F)c(F)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3954314 Ki 0.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 CHEMBL3958282 IC50 0.8 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COCc3ccccc31)CC2 CHEMBL3937865 IC50 0.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(C)n1)CC2 CHEMBL3955174 IC50 0.8 nM
O=C(O)Cc1ccc(OCC(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3913320 IC50 0.8 nM
CCS(=O)(=O)c1ccc(Cn2c(C)c(CC(=O)O)c3cccnc32)c(C(F)(F)F)c1 CHEMBL3932668 IC50 0.8 nM
O=C(O)COC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2cccc(F)c2)[C@H]2CC[C@H]21 CHEMBL4212084 IC50 0.8 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCCc1ccccc1)CC2 CHEMBL3960261 IC50 0.89 nM
CCS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c(C)c1 CHEMBL1778639 IC50 0.9 nM
CS(=O)(=O)c1ccc(CN(C(=O)Cc2ccccc2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036225 Ki 0.9 nM
CCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)oc2ccc(F)cc12 CHEMBL3690183 Ki 0.9 nM
Cc1nn(Cc2ccc(NC(=O)/C=C/c3ccccc3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685973 Ki 0.9 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)c(CC)c1CC(=O)O CHEMBL3686003 Ki 0.9 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)N2CCCCC2)cc1 CHEMBL3667638 IC50 0.9 nM
Cc1ccc(NS(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(F)cc34)cc2)cc1 CHEMBL3667645 IC50 0.9 nM
Cc1c(Cl)cccc1NS(=O)(=O)c1ccc(-c2c(C)c(CC(=O)O)cc3ccc(F)cc23)cc1 CHEMBL3667646 IC50 0.9 nM
Cc1ccc(COC(=O)N2CCc3ncsc3[C@H]2c2cc(Cl)ccc2OCC(=O)O)c(C)c1 CHEMBL3930966 IC50 0.9 nM
Cc1nn(Cc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3899406 Ki 0.9 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3916967 IC50 0.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc31)CC2 CHEMBL3982320 IC50 0.9 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)C[C@@H](C)c1ccccc1)CC2 CHEMBL3985850 IC50 0.9 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc3C1)CC2 CHEMBL3924069 IC50 0.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3cc(F)ccc31)CC2 CHEMBL3946613 IC50 0.9 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccn1)CC2 CHEMBL3919764 IC50 0.9 nM
O=C(O)COC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CC[C@H]21 CHEMBL4207731 IC50 0.9 nM
[3H]c1cc([3H])cc(CN(CCc2cn(CC(=O)O)c3ccccc23)S(=O)(=O)c2ccc(F)cc2)c1 CHEMBL250675 pKd 1.0 nM
CN([C@@H]1CCC2=C(C1)C1C=CC=CC1N2CC(=O)O)S(=O)(=O)c1ccc(F)cc1 CHEMBL563664 IC50 1.0 nM
O=C(O)CCc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cccc(F)c1 CHEMBL1088727 IC50 1.0 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(F)c(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643780 Ki 1.0 nM
CCN(Cc1cc(F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 CHEMBL1668891 IC50 1.0 nM
C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc1ccc(F)cc1 CHEMBL1689127 IC50 1.0 nM
Cc1c(Sc2ccc(Cl)cc2)c2c(-c3ccccc3)cccc2n1CC(=O)O CHEMBL1917438 IC50 1.0 nM
CN(C(=O)C1(C)CCc2c(c3ccccc3n2CC(=O)O)C1)c1cccc(Cl)c1 CHEMBL2181811 IC50 1.0 nM
O=C(O)Cn1c2c(c3cc(C(F)(F)F)ccc31)CN(C(=O)c1ccccc1)CC2 CHEMBL2181810 IC50 1.0 nM
Cc1c(-c2cn(CCCC(F)(F)F)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(=O)O CHEMBL3236950 IC50 1.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(C(F)(F)F)cc3Cc3c(C)noc3C3CC3)c2n1 CHEMBL3338297 IC50 1.0 nM
Cc1ccc(-n2cc(CC(=O)O)c3ccc(C)nc32)c(Cn2c(C)nnc2C)c1 CHEMBL3338270 IC50 1.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(F)cc3Cc3c(C)noc3C3CC3)c2n1 CHEMBL3338296 IC50 1.0 nM
Cc1c(Cc2ccncc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O CHEMBL3674621 Ki 1.0 nM
Cc1c(Cc2cccn2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O CHEMBL3674623 Ki 1.0 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4n3C)cc2F)c(C)c1CC(=O)O CHEMBL3690166 Ki 1.0 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3C)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685922 Ki 1.0 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccccc2OC(F)(F)F)cc1 CHEMBL3667613 IC50 1.0 nM
CN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3ccc(F)cc3n2C1 CHEMBL3673994 IC50 1.0 nM
CN(c1nc2ccc(F)cc2o1)C1CCc2c(CC(=O)O)c3ccc(F)cc3n2C1 CHEMBL3674005 IC50 1.0 nM
CN(c1ncc2ccc(F)cc2n1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674026 IC50 1.0 nM
CCN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674030 IC50 1.0 nM
CCCN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674034 IC50 1.0 nM
CCN(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674035 IC50 1.0 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1cc(F)ccc1F CHEMBL3932945 IC50 1.0 nM
Cc1nn(Cc2ccc(-c3nc4c(Cl)cc(Cl)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3930371 Ki 1.0 nM
CCc1nn(Cc2ccc(-c3nc4cc(OC)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3970655 Ki 1.0 nM
CCc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3910867 Ki 1.0 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1(c3ccccc3)CC1)CC2 CHEMBL3909630 IC50 1.0 nM
O=C(O)Cc1ccc(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c(OCC(F)(F)F)c1 CHEMBL3892170 IC50 1.0 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)C[C@@H](C)c1ccccc1)CC2 CHEMBL3982573 IC50 1.04 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3890081 IC50 1.06 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(F)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643773 Ki 1.1 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643774 Ki 1.1 nM
O=C(O)CCCCc1nc2cc(C3=NOC4(C3)Cc3ccccc3C4)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL3125333 Ki 1.1 nM
Cc1nn(Cc2ccc(NC(=O)/C=C/c3ccc(Cl)cc3)cc2)c(C)c1CC(=O)O CHEMBL3685863 Ki 1.1 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3C)cc2)c(CC)c1CC(=O)O CHEMBL3685886 Ki 1.1 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2F)c(C)c1CC(=O)O CHEMBL3685979 Ki 1.1 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1 CHEMBL3667632 IC50 1.1 nM
CCc1nn(Cc2ccc(-c3nc4c(F)c(F)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3893785 Ki 1.1 nM
CCc1nn(Cc2ccc(-c3nc4c(F)cc(F)cc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3986049 Ki 1.1 nM
Cc1cc2nc(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)cc3)[nH]c2cc1Cl CHEMBL3982629 Ki 1.1 nM
CCc1nn(Cc2ccc(-c3nc4c(F)cc(F)cc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3920928 Ki 1.1 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 CHEMBL3919643 IC50 1.1 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccc(F)cc1)CC2 CHEMBL3934432 IC50 1.1 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccc(Cl)cc1)CC2 CHEMBL3942041 IC50 1.12 nM
COc1ccc(CC(=O)O)cc1-c1ccc(Cl)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1F)CC2 CHEMBL3974897 IC50 1.16 nM
C[C@@H](C(=O)N(C)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1)c1ccc(F)cc1 CHEMBL1641811 IC50 1.2 nM
CN(C(=O)C1(c2ccc(F)cc2)CCC1)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1 CHEMBL1641816 IC50 1.2 nM
CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OC(C)C(=O)O)c1 CHEMBL1917804 Ki 1.2 nM
Cc1c(-c2cn(C(C)C)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(=O)O CHEMBL3236948 IC50 1.2 nM
CC(C)Oc1ccc(S(=O)(=O)N2CC[C@@H](n3cc(CC(=O)O)c4ccc(Cl)cc43)C2)cc1 CHEMBL3693869 IC50 1.2 nM
CN(c1nc2ccc(F)cc2s1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680675 IC50 1.2 nM
COc1cccc2cc(C(=O)Nc3ccc(Cn4nc(C)c(CC(=O)O)c4C)cc3)oc12 CHEMBL3685839 Ki 1.2 nM
CCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)oc2ccc(F)cc12 CHEMBL3690184 Ki 1.2 nM
Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 CHEMBL3685917 Ki 1.2 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685968 Ki 1.2 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccc(F)cc2F)cc1 CHEMBL3667617 IC50 1.2 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2c(F)cccc2F)cc1 CHEMBL3667618 IC50 1.2 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1ccc(F)cc1 CHEMBL3942063 IC50 1.2 nM
Cc1cccc(COC(=O)N2CCc3ncsc3[C@H]2c2cc(Cl)ccc2OCC(=O)O)c1C CHEMBL3931651 IC50 1.2 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cccc(Cl)c1Cl CHEMBL3969285 IC50 1.2 nM
Cc1nn(Cc2ccc(-c3nc4cc(Cl)c(Cl)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3975779 Ki 1.2 nM
Cc1nn(Cc2ccc(-c3nc4cc(Br)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3900604 Ki 1.2 nM
CCc1nn(Cc2ccc(-c3nc4c(F)cccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3903045 Ki 1.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C[C@@H](C)c1ccccc1)CC2 CHEMBL3944664 IC50 1.2 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc31)CC2 CHEMBL3950100 IC50 1.2 nM
CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 CHEMBL3979139 IC50 1.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccn1)CC2 CHEMBL3941153 IC50 1.2 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCCc1ccccc1F)CC2 CHEMBL3978457 IC50 1.28 nM
CC(C)COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3917166 IC50 1.28 nM
CCC[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 CHEMBL1689124 IC50 1.3 nM
C[C@H](Oc1ccc(Cl)cc1CN1CCN(C(=O)Cc2ccc(Cl)cc2)[C@@H](C)C1)C(=O)O CHEMBL1689133 IC50 1.3 nM
CCN(CC)S(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)cc1 CHEMBL1778623 IC50 1.3 nM
CCCS(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)O)c(C)cc1NC(C)=O CHEMBL1917782 Ki 1.3 nM
Cc1c(F)ccc2c1c(Sc1ccc(Cl)cc1)c(C)n2CC(=O)O CHEMBL1917427 IC50 1.3 nM
CC(C)Oc1ccc(S(=O)(=O)N2CCC(n3cc(CC(=O)O)c4ccc(F)cc43)CC2)cc1 CHEMBL3693865 IC50 1.3 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4c(F)cccc4c3C)cc2)c(C)c1CC(=O)O CHEMBL3685837 Ki 1.3 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(C)cc3)cc2)c(CC)c1CC(=O)O CHEMBL3685888 Ki 1.3 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(-c2ccccc2)c1CC(=O)O CHEMBL3685914 Ki 1.3 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685975 Ki 1.3 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccccc2C(F)(F)F)cc1 CHEMBL3667612 IC50 1.3 nM
COc1ccc(CN(C(C)C)S(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(F)cc34)cc2)cc1 CHEMBL3667655 IC50 1.3 nM
CC(C)(C)CCOC(=O)N1CCc2ncsc2[C@H]1c1cc(Cl)ccc1OCC(=O)O CHEMBL3909133 IC50 1.3 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cc(F)ccc1F CHEMBL3892332 IC50 1.3 nM
CCc1nn(Cc2ccc(-c3nc4cc(OC)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3908191 Ki 1.3 nM
CCc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3893720 Ki 1.3 nM
CCc1nn(Cc2ccc(-c3nc4cc(C)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3899086 Ki 1.3 nM
CCc1nn(Cc2ccc(-c3nc4nc(OC)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3892999 Ki 1.3 nM
CCc1nn(Cc2ccc(-c3nc4c(C)cccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3907441 Ki 1.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccn1)CC2 CHEMBL3915050 IC50 1.3 nM
CCS(=O)(=O)c1ccc(Cn2c(C)c(CC(=O)O)c3cccnc32)c(Cl)c1 CHEMBL3931906 IC50 1.3 nM
O=C(O)CCCCc1cc2cc(C(=O)N[C@@H]3CCCc4cc(F)ccc43)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL3930710 Ki 1.31 nM
CC(C)Oc1ccc(OCC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3969751 IC50 1.38 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)COCc1ccccc1Cl)CC2 CHEMBL3927186 IC50 1.38 nM
CCCCC[C@@](C)(O)/C=C/[C@H]1C(=O)C[C@H](O)[C@@H]1C/C=C/CCCC(=O)O CHEMBL180344 EC50 1.4 nM
O=C(O)COc1ccc(Br)cc1C(=O)c1cnn(-c2ccc(Br)cc2)c1 CHEMBL218561 IC50 1.4 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cccc(F)c1 CHEMBL597727 IC50 1.4 nM
O=C(O)Cc1c2n(c3ccccc13)C[C@H](N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL1643789 Ki 1.4 nM
Cc1ccc2c(c1)c(Sc1ccc(S(C)(=O)=O)cc1)c(C)n2CC(=O)O CHEMBL1917443 IC50 1.4 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)n2cccnc12)C(=O)C1CC1 CHEMBL3338150 IC50 1.4 nM
CC(C)Oc1ccc(S(=O)(=O)N2CCC(n3cc(OC=O)c4ccccc43)CC2)cc1 CHEMBL3693868 Ki 1.4 nM
CN(c1nc2cc(Cl)ccc2o1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680655 IC50 1.4 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(C)cc3C)cc2)c(CC)c1CC(=O)O CHEMBL3685892 Ki 1.4 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCCCF CHEMBL3903833 IC50 1.4 nM
Cc1nn(Cc2ccc(-c3nc4ccc(C(F)(F)F)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3952865 Ki 1.4 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc3C1)CC2 CHEMBL3980466 IC50 1.4 nM
O=C(O)Cc1ccc(-c2ccc(F)c3c2CN(C(=O)[C@@H]2C[C@H]2c2ccccc2)CC3)c(OCC(F)(F)F)c1 CHEMBL3984224 IC50 1.4 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(C#N)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3915718 IC50 1.4 nM
O=C(O)COC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2ccc(F)cc2)[C@H]2CC[C@H]21 CHEMBL4202859 IC50 1.4 nM
O=C(O)COc1ccc(Br)cc1C(=O)c1cnn(-c2ccc(Cl)cc2)c1 CHEMBL217393 IC50 1.5 nM
O=C(O)COc1ccc(Br)cc1C(=O)c1cnn(-c2ccccc2)c1 CHEMBL217053 IC50 1.5 nM
O=C(O)Cc1sc(N(c2ccccc2)c2cccnc2)nc1-c1ccc(F)cc1 CHEMBL1087501 IC50 1.5 nM
CCS(=O)(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)c(Cl)c1 CHEMBL1778646 IC50 1.5 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCN(Cc1ccccc1)C2=O CHEMBL3338127 IC50 1.5 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NC(C)C)cc1 CHEMBL3667641 IC50 1.5 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1 CHEMBL3667647 IC50 1.5 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)NC2CCCCC2)cc1 CHEMBL3667651 IC50 1.5 nM
Cc1nc2c(s1)[C@@H](c1cc(Cl)ccc1OCC(=O)O)N(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3937242 IC50 1.5 nM
CCc1nn(Cc2ccc(-c3nc4cc(Br)cnc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3959194 Ki 1.5 nM
C[C@H](CC(=O)N1CCc2c(F)ccc(-c3ccc(CC(=O)O)cc3OCC(F)(F)F)c2C1)c1ccccc1 CHEMBL3962759 IC50 1.5 nM
CN([C@@H]1CCc2c(CC(=O)O)c3cccc(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643783 Ki 1.6 nM
CCCCCN([C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643787 Ki 1.6 nM
O=C(O)Cc1c2n(c3ccccc13)C[C@H](NS(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL1643785 IC50 1.6 nM
CCS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2O[C@H](C)C(=O)O)c(C)c1 CHEMBL1778648 IC50 1.6 nM
Cc1c(Sc2ccc(Cl)cc2)c2cc(F)ccc2n1CC(=O)O CHEMBL1917426 IC50 1.6 nM
CCCCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125329 Ki 1.6 nM
CCCc1nn(Cc2ccc(NC(=O)c3ccccc3)cc2)c(C(C)C)c1CC(=O)O CHEMBL3685923 Ki 1.6 nM
Cc1cc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)c(Cl)c1 CHEMBL3685976 Ki 1.6 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cn2)c(C)c1CC(=O)O CHEMBL3686055 Ki 1.6 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2cc(F)cc(F)c2)cc1 CHEMBL3667621 IC50 1.6 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NCc2ccccc2)cc1 CHEMBL3667642 IC50 1.6 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCn1ncc2ccccc21 CHEMBL3952758 IC50 1.6 nM
Cc1nn(Cc2ccc(-c3nc4cc(Br)ccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3922028 Ki 1.6 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccn1)CC2 CHEMBL3900865 IC50 1.6 nM
CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3910079 IC50 1.6 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCC1CC1)CC2 CHEMBL3922550 IC50 1.6 nM
COc1ccc(CC(=O)O)cc1-c1ccc(Cl)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3950795 IC50 1.68 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(C(F)(F)F)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643775 Ki 1.7 nM
CCOc1ccc(-c2ccc(-c3cc(CC(=O)[O-])ccc3OC)c(CN(CC)C(=O)C3CC3)c2)cn1 CHEMBL1668898 IC50 1.7 nM
CN(C(=O)C1(c2ccc(F)cc2)CCCC1)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1778388 Ki 1.7 nM
N#Cc1cccc(-c2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1778636 IC50 1.7 nM
COc1ccc(C(=O)c2ccccc2)cc1CSc1nc2cc(F)ccc2n1CC(=O)O CHEMBL2048197 IC50 1.7 nM
CCN(c1ncc(Cl)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680661 IC50 1.7 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)C[C@@H](N(CC1CC1)c1ncc(Cl)cn1)CC2 CHEMBL3680664 IC50 1.7 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)NC(C)C)cc1 CHEMBL3667652 IC50 1.7 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1ccc(Cl)cc1 CHEMBL3938604 IC50 1.7 nM
CCc1nn(Cc2ccc(-c3nc4cc(Cl)cnc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3918250 Ki 1.7 nM
CCc1nn(Cc2ccc(-c3nc4c(F)cccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3954491 Ki 1.7 nM
COc1cc(CC(=O)O)cc(OC)c1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3942802 IC50 1.7 nM
Cc1cccc(CCC(=O)N2CCc3c(F)ccc(-c4cc(CC(=O)O)ccc4OC(C)C)c3C2)n1 CHEMBL3913364 IC50 1.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1ccc(F)cc1)CC2 CHEMBL3927763 IC50 1.7 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccc1F)CC2 CHEMBL3901887 IC50 1.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCc1ccccc1)CC2 CHEMBL3896240 IC50 1.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1F)CC2 CHEMBL3949802 IC50 1.7 nM
Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1Cl CHEMBL3981414 IC50 1.7 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccc(F)cc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@H]21 CHEMBL4207935 IC50 1.7 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1F)CC2 CHEMBL3928441 IC50 1.77 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(Cl)nc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1641809 Ki 1.8 nM
CCN([C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643786 Ki 1.8 nM
CN(C(=O)C1(c2ccc(F)cc2)CCC1)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1778524 Ki 1.8 nM
Cc1c(Sc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O CHEMBL1917433 IC50 1.8 nM
CCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125327 Ki 1.8 nM
CCCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125328 Ki 1.8 nM
Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)C2)c2ccc(Cl)cc12 CHEMBL3693859 IC50 1.8 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(-c2ccccc2)c1CC(=O)O CHEMBL3685915 Ki 1.8 nM
CCc1nn(Cc2ccc(NC(=O)c3cccc4ccccc34)cc2)c(C2CC2)c1CC(=O)O CHEMBL3685931 Ki 1.8 nM
CCN(CC)S(=O)(=O)c1ccc(-c2c(C)c(CC(=O)O)cc3ccc(F)cc23)cc1 CHEMBL3667650 IC50 1.8 nM
Cc1cc2nc(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)[nH]c2cc1Cl CHEMBL3959548 Ki 1.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CC(C)(C)Oc3ccccc31)CC2 CHEMBL3951774 IC50 1.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)C1CCc3cccc(OC)c3C1)CC2 CHEMBL3891575 IC50 1.8 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1cccc(C)n1)CC2 CHEMBL3974966 IC50 1.8 nM
O=C(O)Cc1ccc(OC(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3958951 IC50 1.8 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1cccc(F)c1)CC2 CHEMBL3915617 IC50 1.85 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3982372 IC50 1.89 nM
CN([C@@H]1CCc2c(c3ccccc3n2CCC(=O)O)C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL373118 Ki 1.9 nM
O=C(O)COc1ccc(Br)cc1C(=O)c1cnn(-c2ccccc2Br)c1 CHEMBL384979 IC50 1.9 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(-c4ccc(F)cc4)nc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1641810 Ki 1.9 nM
Cc1ccc(S(=O)(=O)N2CCCCC2C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917608 Ki 1.9 nM
COCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125331 Ki 1.9 nM
C[C@@]1(c2nc3ccccc3o2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125160 Ki 1.9 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Br)cc3Cl)cc2)c(CC)c1CC(=O)O CHEMBL3685899 Ki 1.9 nM
Cc1nn(Cc2ccc(NC(=O)/C=C/c3ccccc3)cc2F)c(C)c1CC(=O)O CHEMBL3685983 Ki 1.9 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1ccc(F)cc1 CHEMBL3898082 IC50 1.9 nM
Cc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3893279 Ki 1.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(c3ccc(F)cc3)CC1)CC2 CHEMBL3950297 IC50 1.9 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1OCCc3ccccc31)CC2 CHEMBL3922370 IC50 1.9 nM
O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)[C@@H]2C[C@H]2c2ccccc2)CC3)c1 CHEMBL3900755 IC50 1.9 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccc(F)cc1)CC2 CHEMBL3914037 IC50 1.99 nM
CCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2F)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL570670 IC50 2.0 nM
CCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OCC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL569719 IC50 2.0 nM
CCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL570235 IC50 2.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC(C)C)cc1NS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL569772 IC50 2.0 nM
CS(=O)(=O)c1ccc(N(c2ccccc2)c2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 CHEMBL1076716 IC50 2.0 nM
CN(C(=O)C1(c2ccc(F)cc2)CC1)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1778523 Ki 2.0 nM
O=C(O)COc1ccc(C(F)(F)F)cc1-c1ccccc1-c1ccccc1 CHEMBL1778630 IC50 2.0 nM
CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917584 Ki 2.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1cccc(Cl)c1 CHEMBL1916707 IC50 2.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccc(F)cc1 CHEMBL1916710 IC50 2.0 nM
CCC(=O)Nc1ccc(Oc2cc(CC(=O)O)ccc2OC)c(C(=O)N[C@@H](C)c2ccc(Cl)cc2)c1 CHEMBL1933917 IC50 2.0 nM
CCC(=O)Nc1ccc(Oc2cc(CC(=O)O)ccc2OC)c(C(=O)NCCc2ccc(F)cc2)c1 CHEMBL1933919 IC50 2.0 nM
CCC(=O)Nc1ccc(Oc2cc(CC(=O)O)ccc2OC)c(C(=O)NC(C)(C)Cc2ccc(F)cc2)c1 CHEMBL1933920 IC50 2.0 nM
CCCCNC(=O)c1ccc(Oc2ccc3c(ccn3CC(=O)O)c2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1950868 IC50 2.0 nM
CCCCNC(=O)c1ccc(Cc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1950871 IC50 2.0 nM
COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccc(F)cc2)c2ccccc21 CHEMBL2011450 Kb 2.0 nM
CCCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036207 Ki 2.0 nM
COc1ccc(C(C)=O)cc1CSc1nc2ccccc2n1CC(=O)O CHEMBL2048183 IC50 2.0 nM
COc1ccc(C(C)=O)cc1CSc1nc2cc([N+](=O)[O-])ccc2n1CC(=O)O CHEMBL2048189 IC50 2.0 nM
COc1ccc(C(C)=O)cc1CSc1nc2cc(F)ccc2n1CC(=O)O CHEMBL2048187 IC50 2.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)C[C@H](NC(=O)CC(c1ccccc1)c1ccccc1)CC2 CHEMBL2181809 IC50 2.0 nM
Cc1c(-c2nn(CCOc3ccc(Cl)cc3)c(=O)c3ccccc23)c2cc(Cl)ccc2n1CC(=O)O CHEMBL2205148 IC50 2.0 nM
C[C@]1(c2ccc(Cl)cc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125342 Ki 2.0 nM
Cc1c(Cc2ccc(=O)n(Cc3cc(F)ccc3F)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236958 IC50 2.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(F)cc3Cc3c(C)noc3C)c2n1 CHEMBL3338269 IC50 2.0 nM
Cc1nnc(C2CC2)n1Cc1cc(C(F)(F)F)ccc1-c1cn(CC(=O)O)c2ccc(F)cc12 CHEMBL3338285 IC50 2.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(Cl)cc3Cn3c(C)nnc3Cc3ccccc3)c2n1 CHEMBL3338287 IC50 2.0 nM
COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cc2c3c(n(CC(=O)O)c2C)CCCC3=O)c1 CHEMBL3774415 IC50 2.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(n1CC(=O)O)CCCC2=O CHEMBL3775213 IC50 2.0 nM
Cc1c(Cc2cccnc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O CHEMBL3674618 Ki 2.0 nM
Cc1c(Cc2cccnc2S(=O)(=O)c2ccc(F)cc2)c2cc(F)ccc2n1CC(=O)O CHEMBL3674619 Ki 2.0 nM
Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)CC2)c2cc(Cl)ccc12 CHEMBL3693861 IC50 2.0 nM
CN(c1ncc(C(F)(F)F)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680648 IC50 2.0 nM
CN(c1nc2ccc(Cl)cc2o1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680677 IC50 2.0 nM
CN(c1ncc(Cl)cn1)C1CCc2c(c3cc(Cl)ccc3n2CC(=O)O)C1 CHEMBL3680689 IC50 2.0 nM
CN(c1ncc(F)cn1)[C@@H]1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674018 IC50 2.0 nM
Cc1cnc(N(C)C2CCc3c(CC(=O)O)c4ccc(Cl)cc4n3C2)nc1 CHEMBL3674023 IC50 2.0 nM
CN(c1cnc2cc(F)ccc2n1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674028 IC50 2.0 nM
CC(C)CN(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674033 IC50 2.0 nM
CCC(C)(C)COC(=O)N1CCc2ncsc2[C@H]1c1cc(Cl)ccc1OCC(=O)O CHEMBL3959365 IC50 2.0 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1c(F)cccc1F CHEMBL3926021 IC50 2.0 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1(C)CCCc3ccccc31)CC2 CHEMBL3966461 IC50 2.0 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cc(Cl)ccc1F)CC2 CHEMBL3959537 IC50 2.0 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1Cl)CC2 CHEMBL3891514 IC50 2.0 nM
CCCS(=O)(=O)c1ccc(Cl)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917594 Ki 2.1 nM
COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cc2c3c(n(CC(=O)O)c2C)CCNC3=O)c1 CHEMBL3338109 IC50 2.1 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CC(C)(C)NC2=O CHEMBL3338130 IC50 2.1 nM
Cc1nn(Cc2ccc(-c3nc4cc(F)c(Cl)cc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3914203 Ki 2.1 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1cccc(F)c1)CC2 CHEMBL3913257 IC50 2.1 nM
CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)C[C@@H](C)c1ccccc1)CC2 CHEMBL3903314 IC50 2.1 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cc(F)ccc1F)CC2 CHEMBL3935539 IC50 2.1 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1Cl)CC2 CHEMBL3912862 IC50 2.11 nM
O=C(O)Cc1ccc(OC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3979622 IC50 2.19 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL561132 IC50 2.2 nM
C[C@H]1CN(Cc2cc(Cl)ccc2CC(=O)O)CCN1C(=O)Cc1ccc(Cl)cc1 CHEMBL1689135 IC50 2.2 nM
CN(c1ccc(-c2cc(F)ccc2OCC(=O)O)c(Cl)c1)S(C)(=O)=O CHEMBL1778634 IC50 2.2 nM
CS(=O)(=O)c1ccc(CN(C(=O)c2ccccc2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036224 Ki 2.2 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(=O)n(C(F)F)ccc2n1CC(=O)O CHEMBL3338136 IC50 2.2 nM
Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)CC2)c2ccc(F)cc12 CHEMBL3693864 IC50 2.2 nM
CN(c1ncc(Cl)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680646 IC50 2.2 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4c(Cl)cccc4c3C)cc2)c(C)c1CC(=O)O CHEMBL3690169 Ki 2.2 nM
Cc1nn(Cc2ccc(NC(=O)c3oc4c(Cl)cccc4c3C)cc2F)c(C)c1CC(=O)O CHEMBL3690173 Ki 2.2 nM
Cc1cc(Cn2nc(C)c(CC(=O)O)c2C)ccc1NC(=O)c1ccc(Cl)c(Cl)c1 CHEMBL3685966 Ki 2.2 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2F)c(C)c1CC(=O)O CHEMBL3685982 Ki 2.2 nM
Nc1nc2c(s1)C(c1cc(Cl)ccc1OCC(=O)O)N(C(=O)OCc1ccccc1)CC2 CHEMBL3904863 IC50 2.2 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cc(F)ccc1Cl CHEMBL3924328 IC50 2.2 nM
CCc1nn(Cc2ccc(-c3nc4c(C)cccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3966792 Ki 2.2 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1OCCc3ccccc31)CC2 CHEMBL3954564 IC50 2.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccc1OC)CC2 CHEMBL3973001 IC50 2.2 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccn1)CC2 CHEMBL3981681 IC50 2.2 nM
Cc1ccc2c(c1)c(-c1ccnc3c(Cl)cccc13)c(C)n2CC(=O)O CHEMBL378730 IC50 2.3 nM
CN(C(=O)C(C)(C)c1ccc(F)cc1)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1 CHEMBL1641813 IC50 2.3 nM
C[C@@]1(c2nc3ccccc3s2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125161 Ki 2.3 nM
COCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)oc2ccccc12 CHEMBL3690179 Ki 2.3 nM
Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1 CHEMBL3685918 Ki 2.3 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2ccccc2C(F)(F)F)cc1 CHEMBL3667624 IC50 2.3 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2ccc(F)cc2F)cc1 CHEMBL3639664 IC50 2.3 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCCc1cccc(F)c1 CHEMBL3965621 IC50 2.3 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCc1ccccc1 CHEMBL3978641 IC50 2.3 nM
CCc1nn(Cc2ccc(-c3nc4ccccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3930547 Ki 2.3 nM
Cc1nn(Cc2ccc(-c3nc4cc(F)c(Cl)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3913892 Ki 2.3 nM
Cc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3932046 Ki 2.3 nM
CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3972404 IC50 2.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)/C=C/c1ccccn1)CC2 CHEMBL3949954 IC50 2.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 CHEMBL3981950 IC50 2.3 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccc(Cl)cc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@H]21 CHEMBL4212838 Ki 2.3 nM
CN(C(=O)C1(c2ccc(F)cc2)CC1(C)C)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1 CHEMBL1641815 IC50 2.4 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(-c4ccccc4)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643778 Ki 2.4 nM
CCCCC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036211 Ki 2.4 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2F)c(C)c1CC(=O)O CHEMBL3685980 Ki 2.4 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)N2CCOCC2)cc1 CHEMBL3667657 IC50 2.4 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CC(C)(C)Oc3ncccc31)CC2 CHEMBL3944545 IC50 2.4 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccc(F)cc1)CC2 CHEMBL3986141 IC50 2.4 nM
CN(C)c1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3906204 IC50 2.4 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2cc(F)ccc2N(C(=O)c2ccc(SC(F)(F)F)cc2)[C@H]2CCC[C@H]21 CHEMBL4205047 IC50 2.4 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCN1CCc3ccccc31)CC2 CHEMBL3974570 IC50 2.42 nM
O=C(O)COc1ccc(OC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3940205 IC50 2.47 nM
CN([C@@H]1CCc2c(CC(=O)O)c3cc(F)c(F)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643779 Ki 2.5 nM
CCS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2CCC(=O)O)c(C)c1 CHEMBL1778652 IC50 2.5 nM
Cc1ccc(CCC(=O)N(Cc2ccc(S(C)(=O)=O)cc2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036226 Ki 2.5 nM
O=C(O)CCCCc1nc2cc(C3=NOC(CO)(c4ccccc4)C3)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL3125330 Ki 2.5 nM
C[C@@]1([C@H](O)c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125159 Ki 2.5 nM
O=C(O)Cc1cc(C2CCN(S(=O)(=O)c3ccccc3Cl)CC2)c2cc(F)ccc2c1 CHEMBL3675666 IC50 2.5 nM
CN(c1ncc(F)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680644 IC50 2.5 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(C)c1CC(=O)O CHEMBL3685856 Ki 2.5 nM
Cc1cc(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)c(C)cc1Br CHEMBL3685866 Ki 2.5 nM
Cc1nn(Cc2ccc(NC(=O)c3cccc4c3CCCC4)cc2)c(C)c1CC(=O)O CHEMBL3685878 Ki 2.5 nM
Cc1nn(Cc2ccc(NC(=O)CCc3ccccc3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685971 Ki 2.5 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)[C@@H]1C[C@H]1c1ccccc1 CHEMBL3916496 IC50 2.5 nM
Cc1nn(Cc2ccc(-c3nc4c(Cl)cc(Cl)cc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3937458 Ki 2.5 nM
Cc1nn(Cc2ccc(-c3nc4cc(C(F)(F)F)ccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3944509 Ki 2.5 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C[C@@H](C)c1ccccc1)CC2 CHEMBL3945535 IC50 2.5 nM
C=C(C)CCOC(=O)N1CCc2c(F)ccc(-c3cc(CC(=O)O)ccc3OCC)c2C1 CHEMBL3946352 IC50 2.5 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1OC)CC2 CHEMBL3924017 IC50 2.5 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(F)c1F)CC2 CHEMBL3943582 IC50 2.51 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 CHEMBL3935817 IC50 2.53 nM
Cc1ccc2c(c1)c(-c1ccnc3c(C)cccc13)c(C)n2CC(=O)O CHEMBL209689 IC50 2.6 nM
Cc1ccc2c(c1)c(Sc1ccccc1Cl)c(C)n2CC(=O)O CHEMBL1917442 IC50 2.6 nM
O=C(O)CCCCc1nc2cc(-c3cc(-c4ccccc4)on3)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL3125322 Ki 2.6 nM
C[C@@]1(c2ccc(Cl)cc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125337 Ki 2.6 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C)c1CC(=O)O CHEMBL3685857 Ki 2.6 nM
CCc1nn(Cc2ccc(NC(=O)C3CCCC3)cc2)c(CC)c1CC(=O)O CHEMBL3685909 Ki 2.6 nM
Cc1nn(Cc2ccc(S(=O)(=O)Nc3ccc(F)cc3)cc2)c(C)c1CC(=O)O CHEMBL3686019 Ki 2.6 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1ccc(F)cc1F CHEMBL3920536 IC50 2.6 nM
CCc1nn(Cc2ccc(-c3nc4cc(C#N)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3978912 Ki 2.6 nM
CCc1nn(Cc2ccc(-c3nc4cc(Br)cnc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3964173 Ki 2.6 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccc(F)cc1)CC2 CHEMBL3943881 IC50 2.6 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC1CCCCC1)CC2 CHEMBL3946488 IC50 2.6 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCCc1ccccc1)CC2 CHEMBL3957763 IC50 2.6 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccc1)CC2 CHEMBL3924468 IC50 2.64 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1c(C)[nH]c3ccccc13)CC2 CHEMBL3907980 IC50 2.66 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)NCc1ccccc1 CHEMBL2181753 IC50 2.7 nM
Cc1cc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)cc1 CHEMBL3685860 Ki 2.7 nM
Cc1ccc(NS(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(Cl)cc34)cc2)cc1 CHEMBL3667633 IC50 2.7 nM
COc1ccc(CC(=O)O)cc1-c1cc(F)cc2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3959616 IC50 2.7 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc3C1)CC2 CHEMBL3978829 IC50 2.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccn1)CC2 CHEMBL3948204 IC50 2.7 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(F)c1)CC2 CHEMBL3944499 IC50 2.7 nM
CCc1nn(Cc2ccc(NC(=O)C3CCCCC3)cc2)c(CC)c1CC(=O)O CHEMBL3685895 Ki 2.8 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3Br)cc2)c(CC)c1CC(=O)O CHEMBL3685901 Ki 2.8 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)[C@@H]1C[C@H]1c1cccc(F)c1 CHEMBL3960215 IC50 2.8 nM
CCC(C)COC(=O)N1CCc2ncsc2[C@H]1c1cc(Cl)ccc1OCC(=O)O CHEMBL3969088 IC50 2.8 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(c3ccccc3)CC1)CC2 CHEMBL3919164 IC50 2.8 nM
CC(C)(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3976895 IC50 2.8 nM
O=C(O)Cc1sc(C(c2ccccc2)c2ccccc2)nc1-c1cccc(F)c1 CHEMBL596932 IC50 2.9 nM
CC(C)S(=O)(=O)c1ccc(Cl)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917595 Ki 2.9 nM
CC(C)Oc1ccc(S(=O)(=O)N2CC[C@@H](n3cc(CC(=O)O)c4ccc(F)cc43)C2)cc1 CHEMBL3693870 IC50 2.9 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c(C)c1CC(=O)O CHEMBL3685850 Ki 2.9 nM
Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1 CHEMBL3685919 Ki 2.9 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCCc1ccccc1F)CC2 CHEMBL3976211 IC50 2.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccn1)CC2 CHEMBL3905762 IC50 2.9 nM
CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(=O)O)c2)c(NS(=O)(=O)c2ccccc2)c1 CHEMBL569530 IC50 3.0 nM
CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL570673 IC50 3.0 nM
CCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL568819 IC50 3.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NCC(C)C)cc1NS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL569727 IC50 3.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CCC2)cc1NS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL570009 IC50 3.0 nM
CN([C@@H]1CCc2c(CC(=O)O)c3cc(F)ccc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643771 IC50 3.0 nM
CCN(Cc1cc(NS(=O)(=O)c2ccc(Cl)cc2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 CHEMBL1668890 IC50 3.0 nM
CN(C(=O)C(C)(C)c1ccc(F)cc1)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1778522 Ki 3.0 nM
C[C@@H](C(=O)N(C)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)c1ccc(F)cc1 CHEMBL1778387 IC50 3.0 nM
Cc1ccc(S(=O)(=O)CC(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917586 Ki 3.0 nM
CCCS(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OC(C)C(=O)O)c1 CHEMBL1917802 Ki 3.0 nM
CCN(Cc1cc(-c2ccc(OC)cn2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)C1CC1 CHEMBL1917810 IC50 3.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1Cl CHEMBL1916706 IC50 3.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccc(Cl)cc1 CHEMBL1916708 IC50 3.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1cc(F)cc(F)c1 CHEMBL1916711 IC50 3.0 nM
Cc1ccc2c(c1)c(Sc1cccc(Cl)c1)c(C)n2CC(=O)O CHEMBL1917441 IC50 3.0 nM
CCCCNC(=O)c1ccc(Oc2ccc3c(CC(=O)O)c[nH]c3c2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1950867 IC50 3.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2C)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1951562 IC50 3.0 nM
CCCCC(=O)N(Cc1cccc(OC)c1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036025 Ki 3.0 nM
CCCCC(=O)N(Cc1ccc(OC)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036028 Ki 3.0 nM
COc1ccc(C(=O)N2CCc3ccccc32)cc1CSc1nc2cc(F)ccc2n1CC(=O)O CHEMBL2048204 IC50 3.0 nM
COc1ccc(C(C)=O)cc1CSc1nc2cc(C(F)(F)F)ccc2n1CC(=O)O CHEMBL2048190 IC50 3.0 nM
Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1 CHEMBL2442750 IC50 3.0 nM
C[C@@]1(c2cccc(C#N)c2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125338 Ki 3.0 nM
Cc1c(-c2cn(CC(C)(C)C)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(=O)O CHEMBL3236951 IC50 3.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236955 IC50 3.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccccc3F)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237239 IC50 3.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc2c(c1NS(=O)(=O)c1ccc(Cl)cc1Cl)CC(=O)N2 CHEMBL3287089 IC50 3.0 nM
Cc1c(Cc2ccc(S(=O)(=O)Cc3ccccc3)cc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338118 IC50 3.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338090 IC50 3.0 nM
Cc1ccc2c(CC(=O)O)cc(-c3ccc(C(F)(F)F)cc3Cc3c(C)noc3C3CC3)n2n1 CHEMBL3338294 IC50 3.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(C(F)(F)F)cc3Cc3c(C4CC4)noc3C3CC3)c2n1 CHEMBL3338299 IC50 3.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(Cl)cc3Cc3c(C)noc3Cc3ccccc3)c2n1 CHEMBL3338301 IC50 3.0 nM
CC(C)Oc1ccc(S(=O)(=O)N2CC[C@H](n3nc(CC(=O)O)c4cc(Cl)ccc43)C2)cc1 CHEMBL3693867 IC50 3.0 nM
Cc1nn(Cc2ccc(C(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)c(C)c1CC(=O)O CHEMBL3685996 Ki 3.0 nM
CN(c1ncc2ccccc2n1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674024 IC50 3.0 nM
O=C(O)Cc1c2n(c3cc(Cl)ccc13)CC(N(CC(F)F)c1nc3cc(F)ccc3o1)CC2 CHEMBL3674029 IC50 3.0 nM
CC(C)N(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674031 IC50 3.0 nM
O=C(O)COc1ccc(Cl)cc1C1c2sc(Br)nc2CCN1C(=O)OCc1ccccc1 CHEMBL3958361 IC50 3.0 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1ccccc1F CHEMBL3914709 IC50 3.0 nM
O=C(O)CCC(=O)N(C1CC1)C1c2ccccc2N(C(=O)OCc2ccccc2)C2CCCC21 CHEMBL4204359 Ki 3.0 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1F)CC2 CHEMBL3906634 IC50 3.06 nM
O=C(O)Cc1ccc(OC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)[C@@H]2C[C@H]2c2ccccc2)CC3)c1 CHEMBL3927264 IC50 3.07 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccnc(Cl)c1 CHEMBL589815 IC50 3.1 nM
Cc1cc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)ccn1 CHEMBL589814 IC50 3.1 nM
CN(C(=O)C1(c2ccc(F)cc2)CC1)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1 CHEMBL1641814 IC50 3.1 nM
CN(C)S(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917598 Ki 3.1 nM
CCC(=O)N(Cc1ccc(S(C)(=O)=O)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036220 Ki 3.1 nM
CN(c1nc2cc(F)ccc2s1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680676 IC50 3.1 nM
Cc1cc2ccccc2cc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)cc1 CHEMBL3685874 Ki 3.1 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc(F)c(Br)c3)cc2)c(CC)c1CC(=O)O CHEMBL3686004 Ki 3.1 nM
COc1ccc(CN(C(C)C)S(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(Cl)cc34)cc2)cc1 CHEMBL3667644 IC50 3.1 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C(C)Cc1ccccc1)CC2 CHEMBL3892411 IC50 3.1 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 CHEMBL3942821 IC50 3.1 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C(C)Cc1ccccn1)CC2 CHEMBL3937520 IC50 3.1 nM
O=C(O)Cc1ccc(OCCF)c(-c2ccc(F)c3c2CN(C(=O)[C@@H]2C[C@H]2c2ccccc2)CC3)c1 CHEMBL3942224 IC50 3.1 nM
COc1ccc(CC(=O)O)cc1-c1c(F)ccc2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3899502 IC50 3.19 nM
C[S+]([O-])c1cccc(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917618 Ki 3.2 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c2ccccc12 CHEMBL2023641 IC50 3.2 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3cccc(Cl)c3)cc2)c2ccccc12 CHEMBL2023644 IC50 3.2 nM
CC(C)CC(=O)N(Cc1ccc(S(C)(=O)=O)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036222 Ki 3.2 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(NS(=O)(=O)c2ccccc2)cc1 CHEMBL3667661 IC50 3.2 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL3667611 IC50 3.2 nM
COc1ccc(CNS(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(F)cc34)cc2)cc1 CHEMBL3667654 IC50 3.2 nM
Cc1cccc(C(C)CC(=O)N2CCc3c(F)ccc(-c4cc(CC(=O)O)ccc4OC(C)C)c3C2)n1 CHEMBL3928837 IC50 3.2 nM
CN([C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1641808 Ki 3.3 nM
C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc1ccccc1 CHEMBL1689126 IC50 3.3 nM
CS(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917579 Ki 3.3 nM
CCCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(-c2nnn[nH]2)ccc1F CHEMBL2036016 Ki 3.3 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338105 IC50 3.3 nM
O=C(O)COc1ccc(Br)cc1C(=O)c1cnn(-c2cccc(Br)c2)c1 CHEMBL385472 IC50 3.4 nM
O=C(O)Cc1sc(C(c2ccccc2)c2ccc(O)cc2)nc1-c1ccc(F)cc1 CHEMBL607082 IC50 3.4 nM
CN(C(=O)C1(c2ccc(F)cc2)CCCC1)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1 CHEMBL1641817 IC50 3.4 nM
CCCS(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917592 Ki 3.4 nM
CCN(CC)S(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917599 Ki 3.4 nM
Cc1ccc(S(=O)(=O)NC(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917603 Ki 3.4 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)c2ccccc12 CHEMBL2023645 IC50 3.4 nM
C[C@@]1(c2cc(F)cc(F)c2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125336 Ki 3.4 nM
CCc1nn(Cc2ccc(NC(=O)c3ccccc3)cc2)c(CC)c1CC(=O)O CHEMBL3685887 Ki 3.4 nM
Cc1cc(Cl)ccc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)c(Cl)c1 CHEMBL3685969 Ki 3.4 nM
N#Cc1ccc(OCC(=O)O)c(C2c3scnc3CCN2C(=O)OCc2ccccc2)c1 CHEMBL3900876 IC50 3.4 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COCc3ccccc31)CC2 CHEMBL3906820 IC50 3.4 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccc1F)CC2 CHEMBL3958517 IC50 3.4 nM
O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)CC2COCc4ccccc42)CC3)c1 CHEMBL3899469 IC50 3.4 nM
O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)CC2COc4ccccc42)CC3)c1 CHEMBL3986652 IC50 3.4 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC(C)C)CC2 CHEMBL3975907 IC50 3.4 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cnccn1)CC2 CHEMBL3917765 IC50 3.4 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 CHEMBL3891507 IC50 3.4 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2cc(F)c(Cl)cc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@H]21 CHEMBL4203572 Ki 3.4 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccc(F)c(F)c1 CHEMBL598127 IC50 3.5 nM
CS(=O)(=O)c1ccc(Cl)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917580 Ki 3.5 nM
CS(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)O)ccc1-c1ccccc1Cl CHEMBL1917781 Ki 3.5 nM
Cc1c(Sc2ccc(Cl)cc2)c2c(-c3nccs3)cccc2n1CC(=O)O CHEMBL1917437 IC50 3.5 nM
Cc1c(Sc2ccc(Cl)cc2)c2cc(-c3ccccc3)ccc2n1CC(=O)O CHEMBL1917439 IC50 3.5 nM
Cc1c(Oc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O CHEMBL1917456 IC50 3.5 nM
CCS(=O)(=O)c1ccc(Oc2c(C)n(CC(=O)O)c3ccc(C(F)(F)F)cc23)cc1 CHEMBL1917458 IC50 3.5 nM
O=C(O)Cc1cc(C2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c2cc(F)ccc2c1 CHEMBL3675670 IC50 3.5 nM
CN(c1ncc(Cl)cn1)C1CCc2c(c3cc(C(F)(F)F)ccc3n2CC(=O)O)C1 CHEMBL3680693 IC50 3.5 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)c(C)c1CC(=O)O CHEMBL3685855 Ki 3.5 nM
CCc1c(CC(=O)O)c(C2CC2)nn1Cc1ccc(NC(=O)c2cccc3ccccc23)cc1 CHEMBL3685934 Ki 3.5 nM
CCc1nn(Cc2ccc(NC(=O)OCc3ccccc3Br)cc2)c(CC)c1CC(=O)O CHEMBL3685951 Ki 3.5 nM
Cc1cc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)c(F)c1 CHEMBL3685978 Ki 3.5 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)/C=C/c1ccc(F)cc1F CHEMBL3971521 IC50 3.5 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1ccccc1Cl CHEMBL3981594 IC50 3.5 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1ccccc1 CHEMBL3917314 IC50 3.5 nM
O=C(O)Cc1ccc(-c2ccc(F)c3c2CN(C(=O)CC2CCOc4ccccc42)CC3)c(OCC(F)(F)F)c1 CHEMBL3981996 IC50 3.5 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2cc(F)ccc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@H]21 CHEMBL4208457 IC50 3.5 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)COCc1ccccc1Cl)CC2 CHEMBL3897078 IC50 3.57 nM
COc1ccc(-n2cc(C(=O)c3cc(Br)ccc3OCC(=O)O)cn2)cc1 CHEMBL216367 IC50 3.6 nM
COc1ccc(C(c2ccccc2)c2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 CHEMBL605148 IC50 3.6 nM
Cc1ccc(S(=O)(=O)N2CCOCC2)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917607 Ki 3.6 nM
COCCNS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917610 Ki 3.6 nM
CCCCC(=O)N(Cc1ccc(OC)cc1)c1cc(Cl)cc(-c2nnn[nH]2)c1 CHEMBL2036029 Ki 3.6 nM
COc1ccc(S(=O)(=O)c2ccccc2)c(Cc2c3c(n(CC(=O)O)c2C)CCNC3=O)c1 CHEMBL3338097 IC50 3.6 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2F)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338101 IC50 3.6 nM
CCc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3Br)cc2)c(CC)c1CC(=O)O CHEMBL3685903 Ki 3.6 nM
CCCc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3963787 IC50 3.6 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CC(C)(C)Oc3ccccc31)CC2 CHEMBL3977592 IC50 3.6 nM
C[C@H](CC(=O)N1CCc2c(F)ccc(-c3cc(CC(=O)O)ccc3OCC(F)(F)F)c2C1)c1ccccc1 CHEMBL3913944 IC50 3.6 nM
O=C(O)Cc1sc(Cc2ccc(Cl)cc2)nc1-c1ccc(Oc2ccccc2)cc1 CHEMBL603158 IC50 3.7 nM
CN([C@@H]1CCc2c(CC(=O)O)c3cc(F)c(Cl)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643782 Ki 3.7 nM
O=C(O)Cc1c2n(c3ccccc13)C[C@H](N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL1643790 Ki 3.7 nM
O=C(O)Cc1cnc(C(=O)c2ccc(C(=O)NCCc3ccc(Cl)c(Cl)c3)cc2)c2ccccc12 CHEMBL3093591 IC50 3.7 nM
C[C@@]1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125334 Ki 3.7 nM
C[C@@]1([C@@H](O)c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125158 Ki 3.7 nM
Cc1c(Cc2cc(F)ccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338096 IC50 3.7 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2cc(Cl)ccc2Cl)cc1 CHEMBL3667616 IC50 3.7 nM
CCn1nc(C)cc1CCOC(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O CHEMBL3984755 IC50 3.7 nM
CCc1nn(Cc2ccc(-c3nc4cc(C#N)ccc4[nH]3)cc2)c(CC)c1CC(=O)O CHEMBL3913517 Ki 3.7 nM
Cc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)nc2c1 CHEMBL3894114 Ki 3.7 nM
CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccn1)CC2 CHEMBL3929228 IC50 3.7 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccn1)CC2 CHEMBL3978949 IC50 3.7 nM
CC(C)(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3971828 IC50 3.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1)CC2 CHEMBL3942713 IC50 3.7 nM
COc1ccc(CC(=O)O)cc1-c1ccc(Cl)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccc(Cl)cc1)CC2 CHEMBL3898927 IC50 3.75 nM
Cc1ccc(S(=O)(=O)N(C)C(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917604 Ki 3.8 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3cc4ccccc4o3)cc2)c2ccccc12 CHEMBL3093607 IC50 3.8 nM
CC(C)Oc1ccc(S(=O)(=O)N2CC[C@@H](n3cc(CC(=O)O)c4ccccc43)C2)cc1 CHEMBL3693866 IC50 3.8 nM
Cc1nn(Cc2ccc(NC(=O)c3csc4ccccc34)cc2)c(C)c1CC(=O)O CHEMBL3690195 Ki 3.8 nM
Cc1nn(Cc2ccc(NC(=O)OCc3ccccc3)cc2)c(C)c1CC(=O)O CHEMBL3685942 Ki 3.8 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)/C=C/c1ccccn1)CC2 CHEMBL3934340 IC50 3.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccnn1C)CC2 CHEMBL3891491 IC50 3.8 nM
O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3918881 IC50 3.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1F)CC2 CHEMBL3946443 IC50 3.8 nM
COc1ccc(C(c2ccc(OC)cc2)c2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 CHEMBL606389 IC50 3.9 nM
Cc1c(Cc2cc(Br)ccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338098 IC50 3.9 nM
COc1ccc(S(=O)(=O)c2ccccc2Cc2c3c(n(CC(=O)O)c2C)CCNC3=O)cc1 CHEMBL3338107 IC50 3.9 nM
CCCN(c1ncc(Cl)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680662 IC50 3.9 nM
Cc1cc(Br)ccc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)cc1 CHEMBL3685865 Ki 3.9 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2cccc(Cl)c2)cc1 CHEMBL3667610 IC50 3.9 nM
O=C(O)COc1ccc(Cl)cc1[C@H]1c2scnc2CCN1C(=O)C1CC1c1ccccc1 CHEMBL3893913 IC50 3.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cccc(F)c1)CC2 CHEMBL3890646 IC50 3.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cnccn1)CC2 CHEMBL3897333 IC50 3.9 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1F)CC2 CHEMBL3898843 IC50 3.9 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CC[C@H]21 CHEMBL4215576 IC50 3.9 nM
C[C@H](Oc1ccc(F)cc1-c1ccc(C(=O)N2CCCC2(C)C)c(Cl)c1)C(=O)O CHEMBL2181755 pIC50 3.981 nM
CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(=O)O)c2)c(NS(=O)(=O)c2ccccc2Cl)c1 CHEMBL585197 IC50 4.0 nM
CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(C)c(Cl)c2)c1 CHEMBL569726 IC50 4.0 nM
CCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL583453 IC50 4.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CC2)cc1NS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL569537 IC50 4.0 nM
CN([C@@H]1CCc2c(CC(=O)O)c3cc(F)cc(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643784 Ki 4.0 nM
CCN(Cc1cc(-c2cnn(C)c2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)C1CC1 CHEMBL1668895 IC50 4.0 nM
CC(C)S(=O)(=O)c1ccc(F)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917593 Ki 4.0 nM
COc1ccc(CC(=O)O)cc1-c1ccc(C(F)(F)F)cc1CN(C)C(=O)OCc1ccccc1 CHEMBL1916699 IC50 4.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 CHEMBL1916700 IC50 4.0 nM
COc1ccc(CC(=O)O)cc1-c1ccc(C(F)(F)F)cc1CN(C(=O)OCc1ccccc1)C1CC1 CHEMBL1916701 IC50 4.0 nM
COc1ccc(CC(=O)O)cc1-c1ccc(C(F)(F)F)cc1CN(C(=O)OCc1ccccc1)C1CCC1 CHEMBL1916702 IC50 4.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1cc(Cl)cc(Cl)c1 CHEMBL1916709 IC50 4.0 nM
Cc1c(Oc2ccc(Cl)cc2)c2c(-c3ccccc3)cccc2n1CC(=O)O CHEMBL1917460 IC50 4.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL1933766 IC50 4.0 nM
CCCc1nc(-c2ccc(Oc3ccc(CC(=O)O)cc3OC)c(NS(=O)(=O)c3ccc(Cl)cc3Cl)c2)n[nH]1 CHEMBL1950877 IC50 4.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(C(F)(F)F)cc2Cl)c1 CHEMBL1951561 IC50 4.0 nM
CCCCNC(=O)c1ccc(Oc2cc(F)c(CC(=O)O)cc2F)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1951566 IC50 4.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CCC2)cc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1Cl CHEMBL1951570 IC50 4.0 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c2ccccc12 CHEMBL2023640 IC50 4.0 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)/C=C/c3ccc(Cl)c(Cl)c3)cc2)c2ccccc12 CHEMBL2023651 IC50 4.0 nM
CS(=O)(=O)c1ccc(CN(C(=O)c2cccnc2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036228 Ki 4.0 nM
CCOc1ccc(C(C)=O)cc1CSc1nc2cc(F)ccc2n1CC(=O)O CHEMBL2048194 IC50 4.0 nM
COc1ccc(C(C)=O)cc1CSc1nc2cc(C=O)ccc2n1CC(=O)O CHEMBL2048193 IC50 4.0 nM
Cc1c(CC2=NN(Cc3ccc(F)cc3F)C(=O)CC2)c2cc(F)ccc2n1CC(=O)O CHEMBL2204470 IC50 4.0 nM
Cc1c(CC(=O)O)c(-c2ccncc2)nn1Cc1ccccc1S(=O)(=O)c1ccccc1 CHEMBL2385113 IC50 4.0 nM
CCc1ccc(-c2ccc(C(=O)N3CCc4c(c5ccccc5n4CC(=O)O)C3)cc2)cc1 CHEMBL2385904 IC50 4.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CN(C(=O)Cc1cccc3ccccc13)CC2 CHEMBL2385901 IC50 4.0 nM
O=C(O)Cn1c2c(c3cc(Cl)ccc31)CN(C(=O)c1cccc3ccccc13)CC2 CHEMBL2386080 IC50 4.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CN(C(=O)c1cccs1)CC2 CHEMBL2386075 IC50 4.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c(-c2ccccc2)nn1CC(=O)O CHEMBL3099118 IC50 4.0 nM
Cc1c(-c2cn(CC(F)(F)F)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(=O)O CHEMBL3236949 IC50 4.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3F)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236960 IC50 4.0 nM
Cc1c(Cc2ccc(=O)n(Cc3cccc(F)c3)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237242 IC50 4.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2cccc(Cl)c2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338103 IC50 4.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(C(F)(F)F)cc3CN(CCOc3ccccc3)C(=O)C3CC3)c2n1 CHEMBL3343128 IC50 4.0 nM
COCCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3343129 IC50 4.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(C(=O)NCCc4ccccc4)cc3CSC(C)(C)C)c2n1 CHEMBL3338261 IC50 4.0 nM
Cc1ccc(-n2cc(CC(=O)O)c3ccc(C)nc32)c(Cc2c(C)cnn2CC2CC2)c1 CHEMBL3338282 IC50 4.0 nM
Cc1c(-c2cccc3c2CCN(S(C)(=O)=O)C3)c2cc(F)ccc2n1CC(=O)O CHEMBL3337464 IC50 4.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(Cl)cc3Cn3c(C)nnc3C3CC3)c2n1 CHEMBL3338284 IC50 4.0 nM
COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cn2c(C)c(CC(=O)O)c3ccc(C)nc32)c1 CHEMBL3774971 IC50 4.0 nM
Cc1nn(Cc2ccc(NC(=O)/C=C/c3ccccc3)cc2)c(C)c1CC(=O)O CHEMBL3685862 Ki 4.0 nM
Cc1nn(Cc2ccc(NC(=O)C3[C@H]4C[C@@H]5C[C@@H](C[C@H]3C5)C4)cc2)c(C)c1CC(=O)O CHEMBL3685883 Ki 4.0 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc4ccccc4n3)cc2)c(CC)c1CC(=O)O CHEMBL3686013 Ki 4.0 nM
CN(c1ncc(Cl)cn1)C1CCc2c(CC(=O)O)c3ccc(F)cc3n2C1 CHEMBL3674002 IC50 4.0 nM
Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1 CHEMBL3983909 IC50 4.0 nM
Cc1cc(S(C)(=O)=O)ccc1Cn1c(C)c(CC(=O)O)c2cccnc21 CHEMBL3975922 IC50 4.0 nM
CCS(=O)(=O)c1ccc(Cn2c(C)c(CC(=O)O)c3cccnc32)cc1 CHEMBL4073398 IC50 4.0 nM
O=C(O)Cc1sc(C(c2ccccc2)c2ccccc2)nc1-c1ccc(F)c(F)c1 CHEMBL590398 IC50 4.1 nM
CCS(=O)(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)c(C)c1 CHEMBL1778645 IC50 4.1 nM
COCCN(C)S(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917609 Ki 4.1 nM
C[C@@]1(c2ccc(F)cc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125335 Ki 4.1 nM
Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)CC2)c2ccc(Cl)cc12 CHEMBL3693857 IC50 4.1 nM
CN(c1nc2cc(F)ccc2o1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680666 IC50 4.1 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)N2CCCCC2)cc1 CHEMBL3667649 IC50 4.1 nM
Cc1ccc(S(=O)(=O)N(C)CC(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917605 Ki 4.2 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)c2ccc(C)nn12)C(=O)C1CC1 CHEMBL3343118 IC50 4.2 nM
COc1c(CC(=O)O)c(C)nn1Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1 CHEMBL3685941 Ki 4.2 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)OCC1CCC1 CHEMBL3930535 IC50 4.2 nM
Cc1nn(Cc2ccc(-c3cc4cc(Cl)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3890109 Ki 4.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cccc(C)n1)CC2 CHEMBL3955318 IC50 4.2 nM
CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccccc1)CC2 CHEMBL3912327 IC50 4.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ncc(C)cc1F)CC2 CHEMBL3962829 IC50 4.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OC[C@H](C)c1ccccc1)CC2 CHEMBL3961770 IC50 4.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC(C)CC)CC2 CHEMBL3946538 IC50 4.2 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccc1C)CC2 CHEMBL3901268 IC50 4.22 nM
O=C(O)CCn1c2c(c3ccccc31)C[C@H](NS(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL361812 Ki 4.3 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)S(=O)(=O)c1ccccc1 CHEMBL1643795 Ki 4.3 nM
CN(C(=O)C1(c2ccc(F)cc2)CCOCC1)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1778525 Ki 4.3 nM
CCCc1ccncc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917408 Ki 4.3 nM
CC(=O)Nc1cccc2c1c(Sc1ccc(Cl)cc1)c(C)n2CC(=O)O CHEMBL1914489 IC50 4.3 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1nn(CC(=O)O)c2cccc(F)c12)C(=O)C1CC1 CHEMBL3342994 IC50 4.3 nM
CCCc1c(C)cccc1C(=O)Nc1ccc(Cn2nc(CC)c(CC(=O)O)c2CC)cc1 CHEMBL3685904 Ki 4.3 nM
CCc1nn(Cc2ccc(NC(=O)C(C)C)cc2)c(CC)c1CC(=O)O CHEMBL3685911 Ki 4.3 nM
CCc1nn(C(C)c2ccc(C(=O)Nc3ccc(C(F)(F)F)cc3)cc2)c(CC)c1CC(=O)O CHEMBL3686054 Ki 4.3 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cc(Cl)ccc1F)CC2 CHEMBL3987165 IC50 4.3 nM
COc1ccc(OCC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3972013 IC50 4.36 nM
COc1ccc(S(=O)(=O)N(C)[C@@H]2CCc3c(CC(=O)O)c4ccccc4n3C2)cc1 CHEMBL1643798 Ki 4.4 nM
CCNS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917602 Ki 4.4 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2cc(Cl)ccc2Cl)cc1 CHEMBL3667627 IC50 4.4 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cccc(F)c1 CHEMBL3983464 IC50 4.4 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCN1CCCc3ccccc31)CC2 CHEMBL3907150 IC50 4.49 nM
CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 CHEMBL1689118 IC50 4.5 nM
CC[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 CHEMBL1689123 IC50 4.5 nM
CCCCC(=O)N(Cc1cccc(OC(F)(F)F)c1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036212 Ki 4.5 nM
Cc1nn(Cc2ccc(NC(=O)c3sc4ccc(F)cc4c3C)cc2F)c(C)c1CC(=O)O CHEMBL3690182 Ki 4.5 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3925788 IC50 4.5 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cc(F)ccc1F)CC2 CHEMBL3958478 IC50 4.5 nM
CC(C)c1ccc(S(C)(=O)=O)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917582 Ki 4.6 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)C[C@@H](Nc1ncc(Cl)cn1)CC2 CHEMBL3680640 IC50 4.6 nM
CN(c1nc2ccc(F)cc2o1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680679 IC50 4.6 nM
COc1ccc2c(c1)c1c(n2CC(=O)O)CCC(N(C)c2ncc(Cl)cn2)C1 CHEMBL3680692 IC50 4.6 nM
CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(=O)O)c2)c(NS(=O)(=O)c2cc(C)c(Cl)cc2Cl)c1 CHEMBL570204 IC50 4.7 nM
CC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125326 Ki 4.7 nM
CCN(Cc1cc(F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3343106 IC50 4.7 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)NCc1ccccc1 CHEMBL3343124 IC50 4.7 nM
Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)CC2)c2ccccc12 CHEMBL3693856 IC50 4.7 nM
Cc1nn(Cc2ccc(NC(=O)OCc3ccccc3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685953 Ki 4.7 nM
Cc1ccc(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(Cl)c2)c(C)c1 CHEMBL3685974 Ki 4.7 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1 CHEMBL3667636 IC50 4.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(F)c1)CC2 CHEMBL3972966 IC50 4.7 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1)CC2 CHEMBL3951722 IC50 4.7 nM
Cc1nc2c(s1)[C@@H](c1cc(Cl)ccc1OCC(=O)O)N(C(=O)OCc1ccccc1)CC2 CHEMBL3895907 IC50 4.71 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3912881 IC50 4.72 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cn(C)c3ccccc13)CC2 CHEMBL3933381 IC50 4.74 nM
Nc1cc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)ccn1 CHEMBL592700 IC50 4.8 nM
CCc1nn(Cc2ccc(OCc3ccc(Cl)c(C(F)(F)F)c3)cc2)c(CC)c1CC(=O)O CHEMBL2181750 Ki 4.8 nM
CCOc1ccc(S(=O)(=O)N2CCC(n3cc(C)c4cc(Cl)ccc43)CC2)cc1 CHEMBL3693858 IC50 4.8 nM
O=C(O)Cc1cc(C2CCN(S(=O)(=O)c3ccc(Cl)cc3Cl)CC2)c2cc(F)ccc2c1 CHEMBL3675671 IC50 4.8 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc(F)c(Cl)c3)cc2)c(CC)c1CC(=O)O CHEMBL3686002 Ki 4.8 nM
COC(C)(C)CCOC(=O)N1CCc2ncsc2[C@H]1c1cc(Cl)ccc1OCC(=O)O CHEMBL3917145 IC50 4.8 nM
Cc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)cc3)nc2c1 CHEMBL3902740 Ki 4.8 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccc1F)CC2 CHEMBL3898773 IC50 4.8 nM
COc1ccc(CC(=O)O)cc1-c1cc(F)c(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3959991 IC50 4.82 nM
O=C(O)Cc1c2n(c3ccccc13)C[C@H](N(CC1CC1)S(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL1643788 Ki 4.9 nM
CC(C)Cc1ccncc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917409 Ki 4.9 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c2ccccc12 CHEMBL2023647 IC50 4.9 nM
CCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(-c2nnn[nH]2)ccc1F CHEMBL2036206 Ki 4.9 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(=O)n(C)ccc2n1CC(=O)O CHEMBL3338135 IC50 4.9 nM
CCOc1ccc(S(=O)(=O)N2CCC(n3cc(C)c4cc(Cl)ccc43)C2)cc1 CHEMBL3693860 IC50 4.9 nM
Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)C2)c2cc(Cl)ccc12 CHEMBL3639927 IC50 4.9 nM
Cc1nn(Cc2ccc(-c3nc4c(F)c(F)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3963810 Ki 4.9 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCCc3ccccc31)CC2 CHEMBL3941641 IC50 4.9 nM
CCOc1cc(S(=O)(=O)n2c(C)c(CC(=O)O)c3cccnc32)ccc1C#N CHEMBL557662 IC50 5.0 nM
CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(C)cc2)c1 CHEMBL570001 IC50 5.0 nM
CC1CC(N(C(=O)CCC(=O)O)c2ccccc2)c2ccccc2N1C(=O)c1ccccc1 CHEMBL1081788 IC50 5.0 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(S(C)(=O)=O)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643777 IC50 5.0 nM
CCN(Cc1cc(S(C)(=O)=O)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 CHEMBL1668892 IC50 5.0 nM
Cc1ccc(S(C)(=O)=O)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917578 Ki 5.0 nM
Cc1ccc(S(=O)(=O)Cc2ccccc2)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917587 Ki 5.0 nM
Cc1ccc(S(=O)(=O)N(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917597 Ki 5.0 nM
Cc1ccc(S(=O)(=O)NC(C)(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917600 Ki 5.0 nM
Cc1ccc(S(=O)(=O)N2CCCCC2)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917606 Ki 5.0 nM
CS(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)O)ccc1-c1ccccc1 CHEMBL1917636 Ki 5.0 nM
Cc1c(Oc2ccc(Cl)cc2)c2cc(F)ccc2n1CC(=O)O CHEMBL1917454 IC50 5.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CCC2)cc1CS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL1933913 IC50 5.0 nM
CCCCNC(=O)c1ccc(Oc2ccc3c(CC(=O)O)coc3c2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1950870 IC50 5.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 CHEMBL1951556 IC50 5.0 nM
O=C(O)Cc1ccc(Oc2ccc(C(=O)NC3CCC3)cc2NS(=O)(=O)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL1951568 IC50 5.0 nM
CC(C)(C)NC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2Cl)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1951569 IC50 5.0 nM
O=C(O)Cc1cc(Cl)c(Oc2ccc(C(=O)NC3CCC3)cc2NS(=O)(=O)c2ccc(OC(F)(F)F)cc2Cl)cc1F CHEMBL1951573 IC50 5.0 nM
COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccccc2)c2ccccc21 CHEMBL2011449 IC50 5.0 nM
CCCOc1ccc(C(C)=O)cc1CSc1nc2cc(F)ccc2n1CC(=O)O CHEMBL2048195 IC50 5.0 nM
COc1ccc(C(C)=O)cc1CSc1nc2c(F)cccc2n1CC(=O)O CHEMBL2048186 IC50 5.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccc(C(C)(C)O)cc3)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL2204472 IC50 5.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O CHEMBL2385124 IC50 5.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CN(C(=O)Cc1c[nH]c3ccccc13)CC2 CHEMBL2385902 IC50 5.0 nM
Cc1ccc2c(c1)c1c(n2CC(=O)O)CCN(C(=O)c2cccc3ccccc23)C1 CHEMBL2385898 IC50 5.0 nM
O=C(O)Cn1c2c(c3cc(Cl)ccc31)CN(C(=O)c1ccccc1)CC2 CHEMBL2386066 IC50 5.0 nM
CN(C(=O)/C(C#N)=C/c1cn(CC(=O)O)c2cccc(Cl)c12)c1ccccc1 CHEMBL2391524 IC50 5.0 nM
Cc1c(-c2ccc(=O)n(Cc3ccccc3)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237230 IC50 5.0 nM
Cc1c(Cc2ccc(=O)n(Cc3c(F)cccc3F)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236956 IC50 5.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(n1CC(=O)O)CC(C)(C)NC2=O CHEMBL3338131 IC50 5.0 nM
COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cc2c3c(n(CC(=O)O)c2C)CC(C)(C)NC3=O)c1 CHEMBL3338132 IC50 5.0 nM
CCN(Cc1ccccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3338153 IC50 5.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)COC CHEMBL3343121 IC50 5.0 nM
Cc1ccc2c(n1)c(-c1ccc(C(F)(F)F)cc1Cc1c(C)noc1C)cn2CC(=O)O CHEMBL3338289 IC50 5.0 nM
Cc1ccn2c(CC(=O)O)cc(-c3ccc(C(F)(F)F)cc3Cc3c(C)noc3C3CC3)c2n1 CHEMBL3338293 IC50 5.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(Cl)cc3Cn3c(C)nnc3CCc3ccccc3)c2n1 CHEMBL3338288 IC50 5.0 nM
COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cc2c(C)c(CC(=O)O)c3ccncn23)c1 CHEMBL3774449 IC50 5.0 nM
Cc1c(CC(=O)O)c2ccc(Cl)nc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F CHEMBL3959781 Ki 5.0 nM
CCc1nn(Cc2ccc(NC(=O)C3CCC3)cc2)c(CC)c1CC(=O)O CHEMBL3685908 Ki 5.0 nM
CCc1nn(Cc2ccc(OCc3ccc(OC)c(C(F)(F)F)c3)cc2)c(CC)c1CC(=O)O CHEMBL3686038 Ki 5.0 nM
CN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3ccc(C(F)(F)F)cc3n2C1 CHEMBL3674009 IC50 5.0 nM
CN(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674016 IC50 5.0 nM
CN(c1ncc2cc(F)ccc2n1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674025 IC50 5.0 nM
O=C(O)COc1ccc(Cl)cc1[C@@H]1c2scnc2CCN1C(=O)[C@@H]1C[C@H]1c1ccc(F)cc1 CHEMBL3977329 IC50 5.0 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)COCc1ccccc1Cl CHEMBL3942447 IC50 5.0 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 CHEMBL3914404 IC50 5.0 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2cccc(OC(F)(F)F)c2)[C@H]2CC[C@H]21 CHEMBL4215049 Ki 5.0 nM
CN(c1ncc(Cl)cn1)C1CCc2c(c3ccccc3n2CC(=O)O)C1 CHEMBL3680688 IC50 5.1 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1nc2ccccc2o1 CHEMBL3913777 IC50 5.1 nM
CCc1nn(Cc2ccc(-c3nc4cc(Cl)cnc4[nH]3)cc2F)c(CC)c1CC(=O)O CHEMBL3894021 Ki 5.1 nM
Cc1nn(Cc2ccc(-c3nc4c(F)c(F)ccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3975045 Ki 5.1 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1ccc(F)cc1)CC2 CHEMBL3983096 IC50 5.1 nM
CCC(=O)N(Cc1ccc(S(=O)(=O)C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036216 Ki 5.2 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)OCc3ccc(Cl)c(Cl)c3)cc2)c2ccccc12 CHEMBL3093589 IC50 5.2 nM
Cc1ccc(C(=O)Nc2ccc(C(=O)c3ncc(CC(=O)O)c4ccccc34)cc2)cc1 CHEMBL3093594 IC50 5.2 nM
CCN(Cc1cc(Cl)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3343107 IC50 5.2 nM
CN(c1ccc(Cl)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680674 IC50 5.2 nM
CCc1nn(Cc2ccc(NC(=O)OCc3ccccc3Cl)cc2)c(CC)c1CC(=O)O CHEMBL3685950 Ki 5.2 nM
O=C(O)CN1C(=O)[C@@]2(CC(=O)N(Cc3cc(Cl)ccc3F)C2=O)c2cc(Cl)ccc21 CHEMBL260672 Ki 5.3 nM
Cc1noc(-c2ccccc2)c1CN1C(=O)CC2(C1=O)C(=O)N(CC(=O)O)c1ccc(Cl)cc12 CHEMBL411513 Ki 5.3 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccncc1 CHEMBL602124 IC50 5.3 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1F)CC2 CHEMBL3982163 IC50 5.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccc(F)cc1)CC2 CHEMBL3937597 IC50 5.3 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1cccc(Cl)c1)CC2 CHEMBL3937307 IC50 5.39 nM
Cc1ccc2c(c1)c(-c1ccnc3cc(C(F)(F)F)ccc13)c(C)n2CC(=O)O CHEMBL214304 IC50 5.4 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cc(F)nc(F)c1 CHEMBL589576 IC50 5.4 nM
CS(=O)(=O)c1ccc(CN(C(=O)C2CCCC2)c2cc(F)cc(-c3nnn[nH]3)c2)cc1 CHEMBL2036223 Ki 5.4 nM
CCc1nc2c(F)ccc(OCC(=O)O)c2c(OC(F)F)c1Cc1ccc(-n2cccn2)cc1 CHEMBL2181746 Ki 5.4 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1 CHEMBL3667620 IC50 5.4 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1Cl)CC2 CHEMBL3933750 IC50 5.4 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCCc1ccccc1)CC2 CHEMBL3915072 IC50 5.41 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(F)c1)CC2 CHEMBL3971283 IC50 5.42 nM
O=C(O)CCn1c2c(c3ccccc31)CC(NS(=O)(=O)c1ccc(F)cc1)CC2 CHEMBL298483 Ki 5.5 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL1643796 Ki 5.5 nM
COc1ccc(C(=O)N(CCCc2cccc(OCC(=O)O)c2)CCC(c2ccccc2)c2ccccc2)cc1 CHEMBL1941129 IC50 5.5 nM
Cc1ccc2c(c1)c1c(n2CC(=O)O)CCC(N(C)c2ncc(Cl)cn2)C1 CHEMBL3680690 IC50 5.5 nM
Cc1nn(Cc2ccc(NC(=O)c3ccccc3)cc2Cl)c(C)c1CC(=O)O CHEMBL3685972 Ki 5.5 nM
COc1ccccc1CNC(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O CHEMBL3973722 IC50 5.5 nM
Cc1nn(Cc2ccc(-c3nc4c(F)cc(F)cc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3963030 Ki 5.5 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)O[C@@H](C)c1ccccc1)CC2 CHEMBL3980719 IC50 5.5 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC1CC1)CC2 CHEMBL3972806 IC50 5.5 nM
C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc1ccccc1Cl CHEMBL1689129 IC50 5.6 nM
CC(C)CC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(-c2nnn[nH]2)ccc1F CHEMBL2036205 Ki 5.6 nM
C[C@]1(c2nc3ccccc3s2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125321 Ki 5.6 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NCCO)cc1 CHEMBL3667658 IC50 5.6 nM
Cc1nn(Cc2ccc(-c3nc4c(F)cc(F)cc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3917047 Ki 5.6 nM
CCC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036210 Ki 5.7 nM
Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4cc3Cl)cc2)c(C)c1CC(=O)O CHEMBL3685872 Ki 5.7 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)NCCc1ccccc1 CHEMBL3962766 IC50 5.7 nM
COc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)nc2c1 CHEMBL3930948 Ki 5.7 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cnc(C)s1)CC2 CHEMBL3921760 IC50 5.73 nM
COc1ccc(C(c2ccc(OC)cc2)c2ccc(=O)n(CCCc3cccc(OCC(=O)O)c3)c2)cc1 CHEMBL1941121 IC50 5.8 nM
CCN(Cc1cc(OC(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3343109 IC50 5.8 nM
CCc1nn(Cc2ccc(NC(=O)c3cc(C)ccc3Br)cc2)c(CC)c1CC(=O)O CHEMBL3685896 Ki 5.8 nM
CCc1nn(Cc2ccc(NC(=O)C(C)(C)C)cc2)c(CC)c1CC(=O)O CHEMBL3685907 Ki 5.8 nM
Cc1cc(Cl)ccc1C(=O)Nc1ccc(Cn2nc(C)c(CC(=O)O)c2C)c(F)c1 CHEMBL3685981 Ki 5.8 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)/C=C/c1cnn(C)c1)CC2 CHEMBL3920822 IC50 5.8 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccc1)CC2 CHEMBL3980797 IC50 5.83 nM
COc1ccc(CC(=O)O)cc1-c1c(F)cc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3904397 IC50 5.89 nM
CCN(Cc1cc(C)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3343108 IC50 5.9 nM
COCCN(c1ncc(Cl)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680671 IC50 5.9 nM
COc1ccc(CC(=O)O)cc1-c1ccc(Cl)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3958180 IC50 5.9 nM
CC(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1ccccc1)CC2 CHEMBL3891887 IC50 5.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCOC)CC2 CHEMBL3950007 IC50 5.9 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCC1CCCC1)CC2 CHEMBL3969657 IC50 5.9 nM
Cc1ccc2c(c1)c(-c1ccnc3c(C(F)(F)F)cccc13)c(C)n2CC(=O)O CHEMBL214350 IC50 6.0 nM
Cc1c(Cc2ccc3ccccc3n2)c2cc(F)ccc2n1CC(=O)O CHEMBL560993 IC50 6.0 nM
CN([C@@H]1CCc2c(c3ncccc3n2CC(=O)O)C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL550465 IC50 6.0 nM
Cc1c(CC(=O)O)c2cccnc2n1S(=O)(=O)c1ccc(Cl)c(C#N)c1 CHEMBL559316 IC50 6.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CCCC2)cc1NS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL585385 IC50 6.0 nM
O=C(O)COc1ccc(Cl)cc1CN1CCN(S(=O)(=O)Cc2ccccc2)CC1 CHEMBL1689111 IC50 6.0 nM
Cc1ccc(S(=O)(=O)C(C)C)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917585 Ki 6.0 nM
Cc1ccc(S(=O)(=O)c2ccccc2)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917589 Ki 6.0 nM
CCc1nc(-c2ccc(Oc3ccc(CC(=O)O)cc3OC)c(NS(=O)(=O)c3ccc(Cl)cc3Cl)c2)n[nH]1 CHEMBL1950875 IC50 6.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2Cl)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1951563 IC50 6.0 nM
O=C(O)Cc1ccc(Oc2ccc(C(=O)NC3CCC3)cc2NS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1 CHEMBL1951402 IC50 6.0 nM
COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccc(F)c(F)c2)c2ccccc21 CHEMBL2010810 IC50 6.0 nM
Cc1c(Cc2nc3ccccc3s2)c2cc(F)ccc2n1CC(=O)O CHEMBL2181805 Ki 6.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccncc3F)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL2204473 IC50 6.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CN(C(=O)c1cccc3ccccc13)CC2 CHEMBL2386081 IC50 6.0 nM
C[C@]1(c2ccc(F)cc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125340 Ki 6.0 nM
Cc1c(-c2ccc(=O)n(Cc3c(F)cccc3F)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237233 IC50 6.0 nM
Cc1c(-c2ccc(=O)n(Cc3ccc(F)cc3)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237232 IC50 6.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237243 IC50 6.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCN(C(C)C(F)(F)F)C2=O CHEMBL3338129 IC50 6.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)Cc1ccccc1 CHEMBL3343122 IC50 6.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(Cl)cc3Cc3c(C4CC4)noc3C3CC3)c2n1 CHEMBL3338300 IC50 6.0 nM
Cc1noc(C)c1-c1cccc(-c2c(C)n(CC(=O)O)c3ccc(F)cc23)c1 CHEMBL3338302 IC50 6.0 nM
Cc1ccc2c(CC(=O)O)cn(-c3ccc(F)cc3Cc3c(C)cnn3C)c2n1 CHEMBL3338268 IC50 6.0 nM
CN(c1ncc(C(F)(F)F)cn1)C1CCc2c(CC(=O)O)c3ccc(F)cc3n2C1 CHEMBL3674003 IC50 6.0 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)O[C@H](C)c1ccccc1)CC2 CHEMBL3957462 IC50 6.0 nM
CCc1ccc2c(CC(=O)O)c(C)n(Cc3ccc(S(C)(=O)=O)cc3)c2n1 CHEMBL4086277 IC50 6.0 nM
C[C@H](OC(=O)N1c2ccccc2[C@H](N(C(=O)CCC(=O)O)C2CC2)[C@@H]2CCC[C@@H]21)c1ccc(F)cc1 CHEMBL4213245 Ki 6.0 nM
Cc1c(Sc2ccc(Cl)cc2)c2c(C#N)c(Cl)ccc2n1CC(=O)O CHEMBL1917428 IC50 6.1 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NCc3ccc(Cl)c(Cl)c3)cc2)c2ccccc12 CHEMBL2023653 IC50 6.1 nM
CCc1ccccc1C(=O)Nc1ccc(Cn2nc(CC)c(CC(=O)O)c2CC)cc1 CHEMBL3685900 Ki 6.1 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NC2CCCCC2)cc1 CHEMBL3667640 IC50 6.1 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)NCCO)cc1 CHEMBL3667659 IC50 6.1 nM
Cc1cccc(COC(=O)N2CCc3ncsc3C2c2cc(Cl)ccc2OCC(=O)O)c1C CHEMBL3925909 IC50 6.1 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 CHEMBL3973783 IC50 6.1 nM
Cc1ccc(C(c2ccc(C)cc2)c2ccc(=O)n(CCCc3cccc(OCC(=O)O)c3)c2)cc1 CHEMBL1941120 IC50 6.2 nM
CN(C)c1ccc(C(=O)Nc2ccc(C(=O)c3ncc(CC(=O)O)c4ccccc34)cc2)cc1 CHEMBL3093598 IC50 6.2 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2cccc(F)c2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338102 IC50 6.2 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(NC(=O)c2ccccc2)cc1 CHEMBL3667666 IC50 6.2 nM
Cc1nc2c(s1)C(c1cc(Cl)ccc1OCC(=O)O)N(C(=O)OCc1ccccc1)CC2 CHEMBL3910423 IC50 6.2 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)CC1Cc2ccccc2C1 CHEMBL3982155 IC50 6.2 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1)S(=O)(=O)c1ccc(Cl)s1 CHEMBL1643801 Ki 6.3 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1nn(CC(=O)O)c2cccc(Cl)c12)C(=O)C1CC1 CHEMBL3342993 IC50 6.3 nM
CCc1nn(Cc2ccc(NC(=O)c3ccccc3C3CCCCC3)cc2)c(CC)c1CC(=O)O CHEMBL3685906 Ki 6.3 nM
CCCCOC(=O)N1CCc2c(F)ccc(-c3cc(CC(=O)O)ccc3OCC)c2C1 CHEMBL3956387 IC50 6.3 nM
CCC(=O)N(Cc1cccc(OC(C)C)c1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036030 Ki 6.4 nM
CN(c1ccon1)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680686 IC50 6.4 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCCc1ccccc1 CHEMBL3897937 IC50 6.4 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)C1CC1 CHEMBL2181754 IC50 6.5 nM
O=C(O)COc1ccc(Cl)cc1C1c2sc(C(F)(F)F)nc2CCN1C(=O)OCc1ccccc1 CHEMBL3921709 IC50 6.5 nM
O=C(O)COc1ccc(Cl)cc1[C@H]1c2scnc2CCN1C(=O)C1CC1c1ccccc1C(F)(F)F CHEMBL3977118 IC50 6.5 nM
Cc1ccccc1C1CC1C(=O)N1CCc2ncsc2[C@@H]1c1cc(Cl)ccc1OCC(=O)O CHEMBL3890911 IC50 6.5 nM
Cc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3949067 Ki 6.5 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(OC(F)(F)F)cc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338108 IC50 6.6 nM
CS(=O)(=O)c1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)[C@@H]1C[C@H]1c1ccccc1)CC2 CHEMBL3904977 IC50 6.6 nM
Cc1cccc(C(C)CC(=O)N2CCc3c(F)ccc(-c4cc(CC(=O)O)ccc4OCC(F)(F)F)c3C2)n1 CHEMBL3908526 IC50 6.6 nM
CN(c1nc2ccc(Cl)cc2s1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680669 IC50 6.7 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc(Br)c(F)c3)cc2)c(CC)c1CC(=O)O CHEMBL3686006 Ki 6.7 nM
Cc1c(Cl)cccc1NS(=O)(=O)c1ccc(-c2c(C)c(CC(=O)O)cc3ccc(Cl)cc23)cc1 CHEMBL3667635 IC50 6.7 nM
C[C@H]1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)Cc1cccc(Cl)c1 CHEMBL1689130 IC50 6.8 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(c3cccc(F)c3)CC1)CC2 CHEMBL3959001 IC50 6.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCC1CCCCC1)CC2 CHEMBL3919575 IC50 6.8 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cc(C)nn1C)CC2 CHEMBL3895638 IC50 6.87 nM
CCC(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036213 Ki 6.9 nM
CCOc1ccc(S(=O)(=O)N2CCC(n3cc(C)c4ccc(Cl)cc43)CC2)cc1 CHEMBL3693862 IC50 6.9 nM
CCOc1ccc(S(=O)(=O)N2CCC(n3cc(C)c4ccc(Cl)cc43)C2)cc1 CHEMBL3693863 IC50 6.9 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1cccc(F)c1)CC2 CHEMBL3920569 IC50 6.9 nM
CCCCC[C@H](O)/C=C/[C@H]1C(=O)C[C@H](O)[C@@H]1C/C=C/CCCC(=O)O CHEMBL360785 EC50 7.0 nM
CCNC(=O)c1ccc(Oc2cccc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(C)cc2)c1 CHEMBL584945 IC50 7.0 nM
CCC(=O)Nc1ccc(Oc2cccc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL570652 IC50 7.0 nM
CCCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL569521 IC50 7.0 nM
CN(C(=O)C1(c2ccc(F)cc2)CCOCC1)[C@@H]1CCc2c(CC(=O)O)c3cccnc3n2C1 CHEMBL1641818 IC50 7.0 nM
CCN(Cc1cc(NC(C)=O)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 CHEMBL1668889 IC50 7.0 nM
CCN(Cc1cc(-c2cnc3ccccc3c2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)C1CC1 CHEMBL1668896 IC50 7.0 nM
Cc1ccc(S(=O)(=O)CCc2ccccc2)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917588 Ki 7.0 nM
COc1ccc(-c2ccc(C#Cc3cc(Cl)ccc3OCC(=O)O)cc2S(C)(=O)=O)cc1 CHEMBL1917637 Ki 7.0 nM
CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(C#N)ccc2OCC(=O)O)c1 CHEMBL1917796 Ki 7.0 nM
CCC(=O)Nc1ccc(Oc2cc(CC(=O)O)ccc2OC)c(C(=O)NCc2ccc(Cl)cc2)c1 CHEMBL1933915 IC50 7.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2F)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 CHEMBL1951564 IC50 7.0 nM
O=C(O)Cc1ccc(Oc2ccc(C(=O)NC3CC3)cc2NS(=O)(=O)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL1951567 IC50 7.0 nM
COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccc(Cl)cc2)c2ccccc21 CHEMBL2011451 IC50 7.0 nM
CCCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cccc(-c2nnn[nH]2)c1 CHEMBL2036203 Ki 7.0 nM
Cc1onc(-c2ccccc2)c1CN1C(=O)NC2(C1=O)C(=O)N(CC(=O)O)c1ccc(Cl)cc12 CHEMBL2042237 Ki 7.0 nM
Cc1c(Cc2ccc(S(C)(=O)=O)cc2)c2cc(F)ccc2n1CC(=O)O CHEMBL2181804 Ki 7.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL2204479 IC50 7.0 nM
Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccccc1S(=O)(=O)c1ccccc1 CHEMBL2387692 IC50 7.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CN(C(=O)c1ccccc1)CC2 CHEMBL2386070 IC50 7.0 nM
Cc1ccc2c(c1)c(/C=C(\C#N)C(=O)N(C)c1ccccc1)cn2CC(=O)O CHEMBL2391528 IC50 7.0 nM
CN(C(=O)/C(C#N)=C/c1cn(CC(=O)O)c2ccc(Cl)cc12)c1ccccc1 CHEMBL2391525 IC50 7.0 nM
N#C/C(=C\c1cn(CC(=O)O)c2ccccc12)C(=O)N1Cc2ccccc2Cc2ccccc21 CHEMBL2391519 IC50 7.0 nM
Cc1c(Cc2ccc(=O)n(Cc3c(F)cccc3F)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236957 IC50 7.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCN(C)C2=O CHEMBL3338126 IC50 7.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)n2ccc(C)nc12)C(=O)C1CC1 CHEMBL3343117 IC50 7.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)CC1CC1 CHEMBL3343120 IC50 7.0 nM
Cc1ccc(-n2cc(CC(=O)O)c3ccc(Cc4ccccc4)nc32)c(Cn2c(C)nnc2C)c1 CHEMBL3338283 IC50 7.0 nM
Cc1noc(C2CC2)c1Cc1cc(Cl)ccc1-n1cc(CC(=O)O)c2ccc(Cc3ccccc3)nc21 CHEMBL3338298 IC50 7.0 nM
Cc1nnc(C2CC2)n1Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(F)cc21 CHEMBL3338286 IC50 7.0 nM
Cc1c(Cc2cccnc2S(=O)(=O)c2ccc(Cl)cc2)c2cc(F)ccc2n1CC(=O)O CHEMBL3674620 Ki 7.0 nM
CC(C)Oc1ccc(S(=O)(=O)N2CC[C@@H](n3cc(C(=O)O)c4ccc(Cl)cc43)C2)cc1 CHEMBL3693871 IC50 7.0 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL3667623 IC50 7.0 nM
CN(c1ncc(Cl)cn1)C1CCc2c(CC(=O)O)c3ccc(Cl)cc3n2C1 CHEMBL3674006 IC50 7.0 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cccc(Cl)c1 CHEMBL3911598 IC50 7.0 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCC(C)C)CC2 CHEMBL3984022 IC50 7.0 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@@H]21 CHEMBL4203786 Ki 7.0 nM
Cc1ccc2c(c1)c(-c1ccnc3c(F)cccc13)c(C)n2CC(=O)O CHEMBL213854 IC50 7.1 nM
COc1ccc(Sc2c(C)n(CC(=O)O)c3ccc(C)cc23)cc1 CHEMBL1917444 IC50 7.1 nM
Cc1c(S(=O)(=O)c2ccc(Cl)cc2)c2cc(F)ccc2n1CC(=O)O CHEMBL1917447 IC50 7.1 nM
CC(=O)Nc1cccc2c1c(S(=O)(=O)c1ccc(Cl)cc1)c(C)n2CC(=O)O CHEMBL1917449 IC50 7.1 nM
CCCCC(=O)N(Cc1cc2ccccc2o1)c1cc(-c2nnn[nH]2)ccc1F CHEMBL2036036 Ki 7.1 nM
CCc1nn(Cc2ccc(C(=O)Nc3ccc(Cl)c(F)c3)cc2)c(CC)c1CC(=O)O CHEMBL3686001 Ki 7.1 nM
Cc1ccc(COC(=O)N2CCc3ncsc3C2c2cc(Cl)ccc2OCC(=O)O)c(C)c1 CHEMBL3906598 IC50 7.1 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1csc(C)n1)CC2 CHEMBL3944219 IC50 7.12 nM
COc1cnc(N(C)[C@H]2CCc3c(c4cc(F)ccc4n3CC(=O)O)C2)nc1 CHEMBL3680668 IC50 7.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1nccs1)CC2 CHEMBL3946564 IC50 7.2 nM
COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCn1ncc3cc(F)ccc31)CC2 CHEMBL3950424 IC50 7.25 nM
COc1ccc(C(=O)Nc2ccc(C(=O)c3ncc(CC(=O)O)c4ccccc34)cc2)cc1 CHEMBL2023648 IC50 7.3 nM
CN(c1nc2ccccc2o1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680656 IC50 7.3 nM
O=C(O)COc1ccc(Cl)cc1[C@H]1c2scnc2CCN1C(=O)C1CC1c1ccccc1Cl CHEMBL3915413 IC50 7.3 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1cccc(C)n1)CC2 CHEMBL3946492 IC50 7.3 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2ccc(F)cc2)[C@H]2CC[C@H]21 CHEMBL4210620 Ki 7.3 nM
O=C(O)Cc1ccc(C(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3958270 IC50 7.31 nM
CN(C(=O)Cc1ccc(F)cc1)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1778506 Ki 7.4 nM
O=C(O)CN1C(=O)[C@@]2(NC(=O)N(Cc3cc(Cl)ccc3F)C2=O)c2cc(Cl)ccc21 CHEMBL2042238 IC50 7.4 nM
C[C@]1(Cc2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125162 Ki 7.4 nM
Cc1cc(N(C)C2CCc3c(c4cc(F)ccc4n3CC(=O)O)C2)no1 CHEMBL3680687 IC50 7.4 nM
Cc1nn(Cc2ccc(NC(=O)CCc3ccccc3)cc2)c(C)c1CC(=O)O CHEMBL3685859 Ki 7.4 nM
Cc1nn(Cc2ccc(-c3nc4cc(Br)cnc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3911616 Ki 7.4 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCN1CCc3ccccc31)CC2 CHEMBL3896449 IC50 7.4 nM
O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)CC2OCCc4ccccc42)CC3)c1 CHEMBL3970643 IC50 7.4 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccc(F)cc1 CHEMBL597726 IC50 7.5 nM
C[C@@]1(Cc2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 CHEMBL3125157 Ki 7.5 nM
Cc1ccc(NC(=O)c2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc1Cl CHEMBL3685997 Ki 7.5 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccc1)C2 CHEMBL3897226 IC50 7.54 nM
Cc1onc(-c2ccccc2)c1CN1C(=O)CC2(C1=O)C(=O)N(CC(=O)O)c1ccc(Cl)cc12 CHEMBL262887 Ki 7.6 nM
Cc1ccccc1S(=O)(=O)N(C)[C@@H]1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL1643792 Ki 7.6 nM
CCC(=O)N(Cc1ccc(OC)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036027 Ki 7.6 nM
COc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)cc3)nc2c1 CHEMBL3970287 Ki 7.6 nM
CCCCC(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036214 Ki 7.7 nM
CCN(Cc1ccccc1-n1cc(CC(=O)O)c2ccc(C(F)(F)F)cc21)C(=O)C1CC1 CHEMBL3343116 IC50 7.7 nM
Cc1ccc(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc1 CHEMBL3685853 Ki 7.7 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1F)CC2 CHEMBL3973943 IC50 7.7 nM
O=C(O)CCCCc1cc2cc(-c3noc(Cc4ccc(F)cc4)n3)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL3929125 Ki 7.793 nM
O=C(O)Cc1cnc(C(=O)c2ccc(C(=O)NCCc3ccc(Cl)cc3)cc2)c2ccccc12 CHEMBL2023657 IC50 7.8 nM
N#Cc1ccc(C(=O)Nc2ccc(C(=O)c3ncc(CC(=O)O)c4ccccc34)cc2)cc1 CHEMBL3093596 IC50 7.8 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3343004 IC50 7.8 nM
CCc1nn(Cc2ccc(C(=O)N[C@H]3CC[C@H](c4ccccc4)CC3)cc2)c(CC)c1CC(=O)O CHEMBL3686011 Ki 7.8 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccn1)CC2 CHEMBL3956812 IC50 7.8 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(CC)c1ccccn1)CC2 CHEMBL3925934 IC50 7.8 nM
O=C(O)CCCCc1cc2cc(C(=O)Nc3noc(Cc4ccc(F)cc4)n3)ccc2c(=O)n1-c1ccc(F)cc1 CHEMBL4208892 Ki 7.8 nM
CCS(=O)(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)c(F)c1 CHEMBL1778644 IC50 7.9 nM
Cc1c(S(=O)(=O)c2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O CHEMBL1917450 IC50 7.9 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccccc3)cc2)c2ccccc12 CHEMBL2023638 IC50 7.9 nM
CC(C)Oc1ccc(OCC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3960097 IC50 7.94 nM
Cc1ccc2c(c1)c(-c1ccnc3cc(Cl)ccc13)c(C)n2CC(=O)O CHEMBL212777 IC50 8.0 nM
Cc1c(CC(=O)O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(C#N)c1 CHEMBL559044 IC50 8.0 nM
Cc1noc(C)c1CN1C(c2c(C)n(CC(=O)O)c3ccc(Cl)cc23)c2ccccc2S1(=O)=O CHEMBL1084901 Ki 8.0 nM
CCN(Cc1cc(C(=O)O)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 CHEMBL1668894 IC50 8.0 nM
Cc1ccc(S(=O)(=O)CCCO)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917591 Ki 8.0 nM
COc1cccc(-c2ccc(C#Cc3cc(Cl)ccc3OCC(=O)O)cc2S(C)(=O)=O)c1 CHEMBL1917638 Ki 8.0 nM
COC(=O)N(Cc1ccccc1)Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC CHEMBL1916697 IC50 8.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OC CHEMBL1916704 IC50 8.0 nM
CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2OC)c(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1 CHEMBL1951557 IC50 8.0 nM
COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2cccc(Cl)c2)c2ccccc21 CHEMBL2011452 IC50 8.0 nM
Cc1c(-c2ccc(=O)n(Cc3c(F)cccc3F)c2)c2cc(Cl)ccc2n1CC(=O)O CHEMBL3236945 IC50 8.0 nM
Cc1c(Cc2ccc(=O)n(Cc3cc(F)ccc3F)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3236959 IC50 8.0 nM
Cc1c(Cc2ccc(=O)n(Cc3cccc(F)c3)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237241 IC50 8.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccccc3F)c2)c2cc(F)ccc2n1CC(=O)O CHEMBL3237240 IC50 8.0 nM
COc1cc(CC(=O)O)ccc1Oc1ccc2[nH]c(C3CC3)cc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl CHEMBL3287082 IC50 8.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1cn(CC(=O)O)c2ccncc12)C(=O)C1CC1 CHEMBL3338147 IC50 8.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C(F)F)nc21)C(=O)C1CC1 CHEMBL3343007 IC50 8.0 nM
CCN(Cc1cc(C(=O)NCCc2ccccc2)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 CHEMBL3338154 IC50 8.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)nc(-c2ccccc2)n1CC(=O)O CHEMBL3775081 IC50 8.0 nM
CN(c1ncc(C(F)(F)F)cn1)C1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL3673988 IC50 8.0 nM
CN(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3ccc(C(F)(F)F)cc3n2C1 CHEMBL3674013 IC50 8.0 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1c(C)[nH]c3ccccc13)CC2 CHEMBL3909008 IC50 8.0 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ncc(C)cc1F)CC2 CHEMBL3912411 IC50 8.0 nM
CN(c1nc2ccccc2s1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680657 IC50 8.1 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2cccc(Cl)c2)cc1 CHEMBL3667622 IC50 8.1 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)CCCc1ccccc1F CHEMBL3972052 IC50 8.1 nM
C[C@@H](CC(=O)N1CCc2c(F)ccc(-c3ccc(CC(=O)O)cc3OCC(F)(F)F)c2C1)c1ccccc1 CHEMBL3923852 IC50 8.1 nM
CC(CC(=O)N1CCc2c(F)ccc(-c3cc(CC(=O)O)ccc3OCC(F)(F)F)c2C1)c1ccccn1 CHEMBL3983764 IC50 8.1 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)C(C)Cc1ccccn1)CC2 CHEMBL3960999 IC50 8.1 nM
O=C(O)CCC(=O)N(C1CC1)[C@H]1c2ccccc2N(C(=O)c2cccc(F)c2)[C@H]2CC[C@H]21 CHEMBL4203383 Ki 8.1 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1Cc3ccccc3C1)CC2 CHEMBL3891690 IC50 8.11 nM
CCC(=O)N(Cc1cccc(OC)c1)c1cc(F)cc(-c2nnn[nH]2)c1 CHEMBL2036026 Ki 8.2 nM
O=C(O)Cc1cnc(C(=O)c2ccc(C(=O)Nc3ccc(Cl)cc3)cc2)c2ccccc12 CHEMBL3093590 IC50 8.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1OCCc3ccccc31)CC2 CHEMBL3968838 IC50 8.2 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCCc3cccnc31)CC2 CHEMBL3898552 IC50 8.2 nM
COc1ccc(-n2c(CCCCC(=O)O)cc3cc(C(=O)N[C@H](C)c4ccc(F)cc4)ccc3c2=O)cc1 CHEMBL3974469 Ki 8.202 nM
Cc1ccccc1S(=O)(=O)Nc1ccc(-c2c(C)c(CC(=O)O)cc3ccc(Cl)cc23)cc1 CHEMBL3667664 IC50 8.3 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cc(Cl)ccc1F CHEMBL3958037 IC50 8.3 nM
O=C(O)COc1ccc(F)cc1C1c2scnc2CCN1C(=O)OCc1ccccc1 CHEMBL3905433 IC50 8.3 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CCc3cccc(OC)c3C1)CC2 CHEMBL3953684 IC50 8.3 nM
COc1ccc(C(c2ccccc2)c2nc(-c3ccc(Cl)cc3)c(CC(=O)O)s2)cc1 CHEMBL597942 IC50 8.4 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 CHEMBL3972436 IC50 8.4 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(Cl)cc2)c2c(n1CC(=O)O)CCNC2=O CHEMBL3338106 IC50 8.5 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CCC1 CHEMBL3343119 IC50 8.5 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1cccc(F)c1F CHEMBL3986761 IC50 8.5 nM
Cc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3940456 Ki 8.5 nM
O=C(O)Cc1ccc(OCCF)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 CHEMBL3920008 IC50 8.5 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1F)CC2 CHEMBL3913174 IC50 8.56 nM
CCCc1ccc(S(C)(=O)=O)cc1C#Cc1cc(Cl)ccc1OCC(=O)O CHEMBL1917581 Ki 8.6 nM
CCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917583 Ki 8.6 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(=O)[nH]ccc2n1CC(=O)O CHEMBL3338134 IC50 8.6 nM
O=C(O)CCC(=O)N(C1CCC1)[C@H]1c2ccccc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@@H]21 CHEMBL4203284 Ki 8.6 nM
O=C(O)Cc1sc(C(c2ccccc2)c2ccccc2)nc1-c1ccc(F)cc1 CHEMBL596931 IC50 8.7 nM
Cc1cccc(S(=O)(=O)N(C)[C@@H]2CCc3c(CC(=O)O)c4ccccc4n3C2)c1 CHEMBL1643794 Ki 8.7 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc(OC(F)(F)F)cc3)cc2)c2ccccc12 CHEMBL3093595 IC50 8.7 nM
Cc1nn(Cc2ccc(C(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c(C)c1CC(=O)O CHEMBL3685993 Ki 8.7 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCc1c(Cl)cccc1Cl CHEMBL3965561 IC50 8.7 nM
Cc1nn(Cc2ccc(-c3nc4c(F)cccc4[nH]3)cc2)c(C)c1CC(=O)O CHEMBL3965834 Ki 8.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC1CCCC1)CC2 CHEMBL3910750 IC50 8.7 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC=C(C)C)CC2 CHEMBL3975242 IC50 8.7 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCOc1ccc(F)cc1)CC2 CHEMBL3919971 IC50 8.76 nM
CN([C@@H]1CCc2c(CC(=O)O)c3ccc(C#N)cc3n2C1)S(=O)(=O)c1ccc(F)cc1 CHEMBL1643776 Ki 8.8 nM
CN(c1ncc(Cl)cn1)C1CCc2c(c3cc(OC(F)(F)F)ccc3n2CC(=O)O)C1 CHEMBL3680691 IC50 8.8 nM
Cc1nn(Cc2ccc(NC(=O)c3coc4ccccc34)cc2)c(C)c1CC(=O)O CHEMBL3690193 Ki 8.8 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccncc1)CC2 CHEMBL3955680 IC50 8.8 nM
C[C@@H](NC(=O)c1ccc2c(=O)n(-c3ccc(C#N)cc3)c(CCCCC(=O)O)cc2c1)c1ccc(F)cc1 CHEMBL3957135 Ki 8.838 nM
CCSc1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)cc1 CHEMBL1778622 IC50 8.9 nM
O=C(O)Cc1c(-c2ccccc2)nn(Cc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c1-c1ccccc1 CHEMBL3685929 Ki 8.9 nM
Cc1nn(Cc2ccc(NC(=O)OCc3ccccc3)cc2F)c(C)c1CC(=O)O CHEMBL3685954 Ki 8.9 nM
Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 CHEMBL3667663 IC50 8.9 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)NCc1ccccc1Cl CHEMBL3904676 IC50 8.9 nM
CC(C)(CC(=O)N1CCc2c(F)ccc(-c3ccc(CC(=O)O)cc3OCC(F)(F)F)c2C1)c1ccccc1 CHEMBL3949839 IC50 8.9 nM
Cc1c(CC(=O)O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(F)c1 CHEMBL563949 IC50 9.0 nM
COc1ccc(C(=O)N2c3ccccc3C(N(C(C)=O)c3ccccc3)CC2C)cc1 CHEMBL1080340 IC50 9.0 nM
CCN(Cc1cc(-c2ccc(F)cn2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)C1CC1 CHEMBL1668897 IC50 9.0 nM
CCCS(=O)(=O)c1cccc(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917575 Ki 9.0 nM
CC(C)(C)NC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2Cl)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL1951555 IC50 9.0 nM
CC(C)(C)NC(=O)c1ccc(Oc2cc(F)c(CC(=O)O)cc2Cl)c(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2Cl)c1 CHEMBL1951574 IC50 9.0 nM
CCCCOc1ccc(C(C)=O)cc1CSc1nc2cc(F)ccc2n1CC(=O)O CHEMBL2048196 IC50 9.0 nM
Cc1c(CC(=O)O)c2cc(F)ccc2n1Cc1ccc2ccccc2c1 CHEMBL2181806 Ki 9.0 nM
Cc1c(Cc2ccc(=O)n(Cc3ccccc3)n2)c2cc(F)ccc2n1CC(=O)O CHEMBL2205146 IC50 9.0 nM
O=C(O)Cn1c2c(c3ccccc31)CN(C(=O)c1cccc3ccccc13)CC2 CHEMBL2386079 IC50 9.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CN(C(=O)c1cccc(Cl)c1)CC2 CHEMBL2386077 IC50 9.0 nM
Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCN(C(C)C)C2=O CHEMBL3338128 IC50 9.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2cccnc21)C(=O)C1CC1 CHEMBL3338149 IC50 9.0 nM
CCN(Cc1cc(C(F)(F)F)ccc1-c1nn(CC(=O)O)c2ccc(C)cc12)C(=O)C1CC1 CHEMBL3342999 IC50 9.0 nM
CN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL3673987 IC50 9.0 nM
CN(c1nc2ccc(F)cc2s1)C1CCc2c(CC(=O)O)c3ccccc3n2C1 CHEMBL3673989 IC50 9.0 nM
CN(c1ncc(Cl)cn1)C1CCc2c(CC(=O)O)c3ccc(C(F)(F)F)cc3n2C1 CHEMBL3674007 IC50 9.0 nM
O=C(O)Cc1c2n(c3cc(F)ccc13)CC(Nc1ncc(F)cn1)CC2 CHEMBL3674019 IC50 9.0 nM
O=C(O)CCC(=O)N(CC1CCC1)[C@H]1c2ccccc2N(C(=O)c2ccc(OC(F)(F)F)cc2)[C@H]2CCC[C@H]12 CHEMBL4212522 Ki 9.0 nM
CN(c1ccc(C(F)(F)F)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680672 IC50 9.1 nM
Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccc(Cl)cc2Cl)cc1 CHEMBL3667615 IC50 9.1 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 CHEMBL3985541 IC50 9.1 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)/C=C/c1nc3ccccc3s1)CC2 CHEMBL3892199 IC50 9.14 nM
COc1ccc(CC(=O)O)cc1-c1ccc(C#N)c2c1CN(C(=O)OCc1ccccc1)CC2 CHEMBL3928905 IC50 9.17 nM
O=C(O)COc1cccc(CCCn2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2=O)c1 CHEMBL1941119 IC50 9.2 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)OCC1CCCCC1 CHEMBL3938279 IC50 9.2 nM
CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccn1)CC2 CHEMBL3913026 IC50 9.2 nM
Cc1nn(Cc2ccc(NC(=O)c3ccc(Br)cc3Cl)cc2)c(C)c1CC(=O)O CHEMBL3685876 Ki 9.3 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)NCc1ccccc1F CHEMBL3939303 IC50 9.4 nM
O=C(O)COC(=O)N(C1CC1)C1c2ccccc2N(C(=O)c2ccccc2)C2CCCC21 CHEMBL4205802 Ki 9.4 nM
COc1ccccc1CNC(=S)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O CHEMBL3916227 IC50 9.5 nM
COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCn1ncc3cc(F)ccc31)CC2 CHEMBL3955414 IC50 9.54 nM
COc1ccc(CC(=O)O)cc1-c1ccc(Cl)c2c1CN(C(=O)[C@@H]1C[C@H]1c1cccc(F)c1)CC2 CHEMBL3945515 IC50 9.58 nM
CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CC(C)(C)Oc3ccccc31)CC2 CHEMBL3898724 IC50 9.6 nM
CC1CCc2c(c3cc(NS(=O)(=O)c4ccc(F)cc4)ccc3n2CC(=O)O)C1 CHEMBL359855 IC50 9.7 nM
O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccc(Cl)cc1 CHEMBL605143 IC50 9.7 nM
O=C(O)COc1cccc(CCCN(CCC(c2ccccc2)c2ccccc2)C(=O)c2ccccc2)c1 CHEMBL1941128 IC50 9.7 nM
Cc1csc(N(C)C2CCc3c(c4cc(F)ccc4n3CC(=O)O)C2)n1 CHEMBL3680681 IC50 9.7 nM
O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)CCCc1ccc(F)cc1 CHEMBL3907672 IC50 9.7 nM
Cc1nn(Cc2ccc(-c3nc4c(F)cccc4[nH]3)cc2F)c(C)c1CC(=O)O CHEMBL3908461 Ki 9.7 nM
CN(c1ccc(F)cn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680673 IC50 9.8 nM
O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc([N+](=O)[O-])cc3)cc2)c2ccccc12 CHEMBL3093597 IC50 9.9 nM
CN(c1ncccn1)[C@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 CHEMBL3680652 IC50 9.9 nM
CCc1nn(Cc2ccc(NC(=O)c3c(C)c4ccccc4n3C)cc2)c(CC)c1CC(=O)O CHEMBL3690160 Ki 9.9 nM