CC(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2cc(C(F)(F)F)ccc12 CHEMBL402392 Log Ki 0.0631 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1 CHEMBL427844 Log Ki 0.1 nM
Cc1cc(C(=O)[O-])nn1Cc1cc(Br)ccc1OCc1ccc(Cl)cc1Cl CHEMBL2110364 pIC50 0.1288 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccc(Cl)cc1Cl CHEMBL214971 Log IC50 0.1318 nM
CC(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2cc(Br)ccc12 CHEMBL257134 Log Ki 0.1995 nM
O=C(O)c1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL362543 Ki 0.3 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccc(C(F)(F)F)nc32)n1 CHEMBL4129609 IC50 0.3 nM
CC#CCC(C)[C@H](O)/C=C/[C@@H]1[C@H]2C/C(=C/CCCC(=O)O)C[C@H]2C[C@H]1O CHEMBL494 EC50 0.3 nM
CC(C)COc1ccc(Cl)cc1Cc1ccc(C(=O)[O-])o1 CHEMBL403330 Log Ki 0.3162 nM
CC(=O)Nc1ccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)cc1C(=O)O CHEMBL387969 Log IC50 0.3981 nM
COc1ccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)cc1C(=O)O CHEMBL228586 Log IC50 0.3981 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 CHEMBL1915012 pKi 0.3981 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccc(C(F)(F)F)cc32)n1 CHEMBL3127163 Ki 0.45 nM
CC(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL257997 Ki 0.5 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(N)cc(C(=O)O)c1 CHEMBL390189 Log IC50 0.5012 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccc(F)cc1F CHEMBL214967 Log IC50 0.5248 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1Cl CHEMBL215992 Log Ki 0.5495 nM
O=C(O)c1cccc(-n2cccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL383090 Log Ki 0.5888 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(OC(F)F)c(C(=O)O)c1 CHEMBL387878 Log IC50 0.631 nM
O=C(O)c1csc(-n2nc(C3=CCCCO3)c3ccc(C(F)(F)F)cc32)n1 CHEMBL4126319 IC50 0.7 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL377852 Log Ki 0.7079 nM
Cc1c(N)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2)cc1C(=O)O CHEMBL228593 Log IC50 0.7943 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2)c1 CHEMBL430360 Log IC50 0.7943 nM
O=C(O)c1cccc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3F)CCC2)n1 CHEMBL234940 pA2 0.7943 nM
Cc1cc(C(=O)[O-])nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL270208 Log Ki 0.7943 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3c2-c2ccccc2C3)n1 CHEMBL3092131 IC50 0.9 nM
O=C(O)c1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL362851 Kb 1.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cccc2F)n1-c1cccc(C(=O)O)c1 CHEMBL211534 Log IC50 1.0 nM
Cc1ccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)cc1C(=O)O CHEMBL231184 Log Ki 1.0 nM
CC(C)Cc1cn(-c2nc(C(=O)[O-])co2)c2cc(Cl)ccc12 CHEMBL402338 Log Ki 1.0 nM
Cc1ccc2c(-c3ccccc3)nn(-c3nc(C(=O)O)cs3)c2c1 CHEMBL3127157 IC50 1.0 nM
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O CHEMBL548 IC50 1.1 nM
COc1ccc2c(-c3ccccc3)nn(-c3nc(C(=O)O)cs3)c2c1 CHEMBL3127159 IC50 1.1 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1OCc1ccc(F)cc1F CHEMBL384332 Log Ki 1.122 nM
Cc1ccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)cc1C(=O)O CHEMBL395248 Log IC50 1.259 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1ccc(F)c(C(=O)O)c1 CHEMBL230765 Log IC50 1.259 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)c2cc[nH]c2c1 CHEMBL228963 Log IC50 1.259 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)cc(N2CCCCC2=O)c1 CHEMBL428367 Log IC50 1.259 nM
CC(=O)N(C)c1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1 CHEMBL390238 Log IC50 1.259 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccccc2)c1 CHEMBL234727 Log IC50 1.259 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccccc2)c1 CHEMBL234519 Log IC50 1.259 nM
CC(C)Cc1cn(-c2ccc(C(=O)[O-])o2)c2cc(Cl)ccc12 CHEMBL403407 Log Ki 1.259 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/[C@@H](O)COc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3804978 EC50 1.4 nM
Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cc(F)cc2F)n1-c1cccc(C(=O)O)c1 CHEMBL210394 Log IC50 1.585 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1cc(NS(C)(=O)=O)cc(C(=O)O)c1 CHEMBL234945 Log IC50 1.585 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(I)ccc2OCc2ccc(F)cc2F)c1 CHEMBL390038 Log IC50 1.585 nM
Cc1ncc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3)CCC2)cc1C(=O)O CHEMBL389796 Log IC50 1.585 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)N[C@H](C)c2ccccc2)cc1 CHEMBL233768 Log IC50 1.585 nM
O=C([O-])c1coc(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL257464 Log Ki 1.585 nM
Cc1c(N)cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccccc2)cc1C(=O)O CHEMBL426913 Log IC50 1.995 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1ccc(OC(F)F)c(C(=O)O)c1 CHEMBL228638 Log IC50 1.995 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(O)c(C(=O)O)c1 CHEMBL395488 Log IC50 1.995 nM
Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccccc2)n1-c1ccc(F)c(C(=O)O)c1 CHEMBL230766 Log IC50 1.995 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)cc(N2CCCC2=O)c1 CHEMBL234946 Log IC50 1.995 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL234518 Log IC50 1.995 nM
O=C(O)c1cncc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3F)CCC2)n1 CHEMBL389996 Log IC50 1.995 nM
Cc1cc(C(=O)[O-])oc1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL407175 Log Ki 1.995 nM
O=C([O-])c1ccc(Cc2cc(Cl)ccc2OCc2ccccc2)o1 CHEMBL272793 Log Ki 1.995 nM
CCCC(=O)Nc1cc(C(=O)O)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL516324 pIC50 1.995 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915252 pIC50 1.995 nM
O=C(O)c1csc(-n2nc3c(c2-c2ccccc2)CCc2ccccc2-3)n1 CHEMBL3092133 IC50 2.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccc(F)cc32)n1 CHEMBL3127156 IC50 2.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccccc32)n1 CHEMBL3127175 IC50 2.4 nM
Cc1ccc(COc2ccc(Br)cc2-c2ccc(C)n2-c2cccc(C(=O)O)c2)cc1 CHEMBL209685 Log IC50 2.512 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)c2ccccc2c1 CHEMBL414978 Log IC50 2.512 nM
Cc1ccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2F)cc1C(=O)O CHEMBL397655 Log IC50 2.512 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1ccc(Cl)c(C(=O)O)c1 CHEMBL230875 Log IC50 2.512 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)c1 CHEMBL390190 Log IC50 2.512 nM
O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(Cl)cc3F)CCC2)c1 CHEMBL390188 Log IC50 2.512 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)NCc2ccccn2)cc1 CHEMBL232117 Log IC50 2.512 nM
Cc1ccc(-c2ccccc2OCc2ccccc2)n1-c1cccc(C(=O)NS(=O)(=O)c2ccccc2)c1 CHEMBL232341 Log IC50 2.512 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)NS(=O)(=O)c2ccccc2)c1 CHEMBL232340 Log IC50 2.512 nM
CCOc1ccc(Cc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C(F)(F)F)cc3)o2)cc1 CHEMBL233335 Log IC50 2.512 nM
CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(C(=O)[O-])n1 CHEMBL467510 pKi 2.512 nM
O=C(O)c1cncc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL184947 Ki 3.0 nM
OC(c1cncc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1)C(F)(F)F CHEMBL182368 Ki 3.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2F)n1-c1cccc(C(=O)O)c1 CHEMBL212672 Log IC50 3.162 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccccc1Cl CHEMBL402880 Log IC50 3.162 nM
Cc1c(N)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccccc2)cc1C(=O)O CHEMBL388294 Log IC50 3.162 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cc(N)cc(C(=O)O)c1 CHEMBL234302 Log IC50 3.162 nM
O=C(O)c1ccnc(C2=C(c3cc(Br)ccc3OCc3ccc(F)cc3)CCC2)c1 CHEMBL395542 Log IC50 3.162 nM
O=C(O)c1cccc(-n2cncc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL207293 Log Ki 3.548 nM
CNS(=O)(=O)c1cc(CCNC(=O)CN(c2ccccc2C)S(=O)(=O)c2ccc(C)cc2)ccc1O CHEMBL241671 Log Ki 3.715 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cccc(C(=O)O)c1 CHEMBL211088 Log IC50 3.981 nM
Cc1c(N)cc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccccc2)cc1C(=O)O CHEMBL228592 Log IC50 3.981 nM
Cc1c(N)cc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccc(F)cc2)cc1C(=O)O CHEMBL228644 Log IC50 3.981 nM
CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(F)ccc2OCc2ccc(F)cc2)c1 CHEMBL234303 Log IC50 3.981 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(N)cc(C(=O)O)c1 CHEMBL234301 Log IC50 3.981 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(Cl)cc(C(=O)O)c1 CHEMBL389995 Log IC50 3.981 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cc(Cl)cc(C(=O)O)c1 CHEMBL234721 Log IC50 3.981 nM
CNC(=O)c1ccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)cc1 CHEMBL233137 Log IC50 3.981 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(C(=O)NS(C)(=O)=O)c1 CHEMBL391286 Log IC50 3.981 nM
CCOc1ccc(Cc2nnc(CN(c3cccc(Cl)c3C)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL231759 Log IC50 3.981 nM
CC(C)(C)CCc1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL255675 Log Ki 3.981 nM
O=C(O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1 CHEMBL514574 pIC50 3.981 nM
COCC(=O)Nc1cc(C(=O)O)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL458452 pIC50 3.981 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C3CCCCC3)oc12 CHEMBL1915015 pIC50 3.981 nM
OC(O)(c1cncc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1)C(F)(F)F CHEMBL185346 Ki 4.0 nM
O=C(Cc1ccccc1)Nc1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL180046 Ki 4.0 nM
O=C(O)c1csc(-n2nc(C3=CCCCC3)c3ccccc32)n1 CHEMBL3127170 IC50 4.0 nM
COc1ccc(-c2nn(-c3nc(C(=O)O)cs3)c3ccccc23)cc1 CHEMBL3127167 IC50 4.0 nM
O=C(O)c1cccc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)c1 CHEMBL207577 Log Ki 4.266 nM
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)N1C/C=C/CCCC(=O)O CHEMBL413509 Ki 4.5 nM
O=C(O)c1csc(-n2nc(-c3ccc(F)cc3)c3ccccc32)n1 CHEMBL3127164 IC50 4.5 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(Cl)cc2Cl)n1-c1cccc(C(=O)O)c1 CHEMBL211059 Log IC50 5.012 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)c(F)c2)n1-c1cccc(C(=O)O)c1 CHEMBL208934 Log IC50 5.012 nM
Cc1ccc(-c2cc(Br)ccc2OCC(C)C)n1-c1cccc(C(=O)O)c1 CHEMBL378120 Log IC50 5.012 nM
Cc1ccc(-c2cc(Cl)ccc2OCC(C)C)n1-c1cccc(C(=O)O)c1 CHEMBL209800 Log IC50 5.012 nM
Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL212688 Log IC50 5.012 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)c2ccccc2c1 CHEMBL228746 Log IC50 5.012 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1ccc(OC(F)F)c(C(=O)O)c1 CHEMBL374824 Log IC50 5.012 nM
COC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL234728 Log IC50 5.012 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)cc(N2CCCS2(=O)=O)c1 CHEMBL390660 Log IC50 5.012 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cc(Br)cc(C(=O)O)c1 CHEMBL388242 Log IC50 5.012 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(Br)cc(C(=O)O)c1 CHEMBL234722 Log IC50 5.012 nM
O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(F)cc3F)CCC2)c1 CHEMBL387605 Log IC50 5.012 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)N[C@@H](C)c2ccccc2)cc1 CHEMBL391026 Log IC50 5.012 nM
Cc1noc(C)c1S(=O)(=O)NC(=O)c1cccc(-n2c(C)ccc2-c2ccccc2OCc2ccccc2)c1 CHEMBL391287 Log IC50 5.012 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(C)cc1 CHEMBL234399 pA2 5.012 nM
Cc1cc(C(=O)Nc2ccc(CN(C)C)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL492238 pIC50 5.012 nM
O=C(O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1 CHEMBL457142 pIC50 5.012 nM
Cc1cc(C(N)=O)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915254 pIC50 5.012 nM
Cc1cc(C(=O)NC2CC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1914467 pIC50 5.012 nM
Cc1ccc(-c2cc(Br)ccc2OCc2cccc(F)c2F)n1-c1cccc(C(=O)O)c1 CHEMBL378641 Log IC50 6.31 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1cccc(C(=O)O)c1 CHEMBL208791 Log IC50 6.31 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1cccc(C(=O)O)c1 CHEMBL208912 Log IC50 6.31 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)c2ccccc2c1 CHEMBL228695 Log IC50 6.31 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)ccc1F CHEMBL395310 Log IC50 6.31 nM
Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)ccc1F CHEMBL395523 Log IC50 6.31 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)ccc1F CHEMBL266258 Log IC50 6.31 nM
O=C(O)c1cccc(C2=C(c3ccccc3OCc3ccccc3)CCC2)c1 CHEMBL395582 Log IC50 6.31 nM
O=C(O)c1cnnc(C2=C(c3cc(Cl)ccc3OCc3ccc(F)cc3F)CCC2)c1 CHEMBL233245 Log IC50 6.31 nM
CCOc1ccc(Cc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL441126 Log IC50 6.31 nM
COc1ccc(Cc2nnc(CN(c3cccc(Cl)c3C)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL399613 Log IC50 6.31 nM
O=C([O-])c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL255652 Log IC50 6.31 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccccc1 CHEMBL213221 Log IC50 6.31 nM
Cc1cc(C(=O)[O-])nn1Cc1cc(Br)ccc1OCc1ccccc1 CHEMBL258184 Log IC50 6.31 nM
CC(C)Cc1cn(Cc2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL403892 Log IC50 6.31 nM
Cc1cc(NC(=O)CC2CCCCC2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL404297 pIC50 6.31 nM
Cc1cc(C(=O)Nc2ccc(CO)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL520438 pIC50 6.31 nM
Cc1cc(C(=O)Nc2ccc(CN3CCCCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL493065 pIC50 6.31 nM
Cc1cc(C(=O)Nc2ccc(CN3CCCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL494282 pIC50 6.31 nM
CCC(=O)Nc1cc(C(=O)O)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL456496 pIC50 6.31 nM
Cc1cc(C(=O)NC[C@H]2CCCO2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915262 pIC50 6.31 nM
O=C(O)c1cccc(-c2ncccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL206096 Log Ki 6.607 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccc(F)cc1 CHEMBL215453 Log IC50 7.413 nM
O=C(CCSCc1ccco1)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL358653 pA2 7.943 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL377649 Log IC50 7.943 nM
Cc1ccc(-c2cc(Br)ccc2OCc2cc(F)ccc2F)n1-c1cccc(C(=O)O)c1 CHEMBL209078 Log IC50 7.943 nM
Cc1cc(C(=O)O)nn1Cc1cc(F)ccc1OCc1ccc(F)cc1F CHEMBL214914 Log Ki 7.943 nM
Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccc(F)cc2)n1-c1ccc(F)c(C(=O)O)c1 CHEMBL388478 Log IC50 7.943 nM
Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)cc(N2CCCS2(=O)=O)c1 CHEMBL388038 Log IC50 7.943 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C(N)=O)cc1 CHEMBL232932 Log IC50 7.943 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(S(=O)(=O)NC(=O)c2ccccc2)cc1 CHEMBL232543 Log IC50 7.943 nM
COc1ccc(Nc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C(F)(F)F)cc3)o2)cc1 CHEMBL232950 Log IC50 7.943 nM
COc1ccc(Cc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL399614 Log IC50 7.943 nM
CC(C)COc1ccc(Cl)cc1Cc1nc(C(=O)[O-])cs1 CHEMBL255009 Log IC50 7.943 nM
Cc1cc(NC(=O)OC(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL256092 pA2 7.943 nM
Cc1cc(C(=O)Nc2ccc(CN(C)C)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL480950 pIC50 7.943 nM
Cc1cc(C(=O)Nc2ccc(CN3CCOCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL523679 pIC50 7.943 nM
CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1 CHEMBL523158 pIC50 7.943 nM
CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1 CHEMBL492237 pIC50 7.943 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 CHEMBL467114 pKi 7.943 nM
Cc1cc(C(=O)N[C@H]2CC[C@H](O)CC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915261 pIC50 7.943 nM
NS(=O)(=O)c1cccc(-c2ccsc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL2113029 Ki 8.0 nM
Nc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1-c1ccccc1 CHEMBL3092130 Ki 8.0 nM
Cc1cc(C(=O)O)nn1Cc1ccccc1OCc1ccc(Cl)cc1Cl CHEMBL213875 Log Ki 8.318 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccc(Cl)cc1 CHEMBL215400 Log Ki 8.71 nM
CC(NC(=O)c1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1)c1cccnc1 CHEMBL360592 Ki 9.0 nM
O=C(O)c1ccn(Cc2cc(Br)ccc2OCc2ccccc2)n1 CHEMBL213412 Log IC50 9.772 nM
CC(C)(C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)c1ccccc1 CHEMBL314533 Ki 10.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(Cl)cc2)n1-c1cccc(C(=O)O)c1 CHEMBL211700 Log IC50 10.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2cccc(Cl)c2)n1-c1cccc(C(=O)O)c1 CHEMBL210261 Log IC50 10.0 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)cc(C(F)(F)F)c1 CHEMBL429259 Log IC50 10.0 nM
O=C(O)c1cncc(C2=C(c3cc(C(F)(F)F)ccc3OCc3ccccc3)CCC2)c1 CHEMBL233043 Log IC50 10.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(C(=O)N(C)C)c1 CHEMBL231723 Log IC50 10.0 nM
CCc1ccccc1N(CC(=O)NCc1ccc(Cl)cc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL240436 Log Ki 10.0 nM
Cc1cc(C(=O)[O-])nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL404525 Log IC50 10.0 nM
Cc1ccc2c(CC(C)C)cn(-c3nc(C(=O)[O-])cs3)c2c1 CHEMBL402656 Log IC50 10.0 nM
Cc1cc(NC(=O)CC(C)(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254150 pIC50 10.0 nM
Cc1cc(C(=O)Nc2c(F)cccc2F)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL404711 pIC50 10.0 nM
Cc1cc(C(=O)[O-])nn1C(C)c1cc(Cl)ccc1OCc1ccccc1 CHEMBL256785 pIC50 10.0 nM
Cc1cc(C(=O)Nc2ccc(CN3CCOCC3)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL479591 pIC50 10.0 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 CHEMBL467720 pIC50 10.0 nM
O=C(O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL515981 pIC50 10.0 nM
CC(C)C(=O)Nc1cc(C(=O)O)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL458448 pIC50 10.0 nM
CC(=O)Nc1cc(C(=O)O)cc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL456495 pIC50 10.0 nM
Cc1cc(C(=O)NN2CCOCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915264 pIC50 10.0 nM
Cc1cc(C(=O)NC(C)C)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915253 pIC50 10.0 nM
Cc1cc(C(=O)NC(C)(C)C)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915255 pIC50 10.0 nM
CO[C@](C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)(c1ccccc1)C(F)(F)F CHEMBL415310 Ki 12.0 nM
O=C(O)c1csc(-n2nc(-c3ccc(Cl)cc3)c3ccccc32)n1 CHEMBL3127166 IC50 12.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ncc(C(F)(F)F)cc32)n1 CHEMBL4128163 IC50 12.0 nM
O=C(O)c1csc(Cn2nc(-c3ccccc3)c3ccc(C(F)(F)F)cc32)n1 CHEMBL4129545 IC50 12.0 nM
CN(C)c1ccc2c(-c3ccccc3)nn(Cc3nc(C(=O)O)cs3)c2n1 CHEMBL4129401 IC50 12.0 nM
O=C(O)c1csc(N2N=C(c3ccccc3)C3CCC(C(F)(F)F)CC32)n1 CHEMBL4126167 IC50 12.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(C(F)(F)F)cc2F)n1-c1cccc(C(=O)O)c1 CHEMBL212471 Log IC50 12.59 nM
Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cccc2Cl)n1-c1cccc(C(=O)O)c1 CHEMBL379753 Log IC50 12.59 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2Cl)n1-c1cccc(C(=O)O)c1 CHEMBL380046 Log IC50 12.59 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cc(C(=O)O)c2ccccc2c1 CHEMBL390081 Log IC50 12.59 nM
Cc1ccc(-c2cc(F)ccc2OCc2ccc(F)cc2)n1-c1ccc(F)c(C(=O)O)c1 CHEMBL230874 Log IC50 12.59 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)cc(C(F)(F)F)c1 CHEMBL388243 Log IC50 12.59 nM
O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(Cl)cc3)CCC2)c1 CHEMBL428370 Log IC50 12.59 nM
O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccccc3)CCC2)c1 CHEMBL397687 Log IC50 12.59 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)NCc2cccnc2)cc1 CHEMBL401023 Log IC50 12.59 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3ccc(N(C)C)cc3)o2)c2cccc(Cl)c2C)cc1 CHEMBL439559 Log IC50 12.59 nM
CC(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2ccccc12 CHEMBL401785 Log Ki 12.59 nM
Cc1cc(NC(=O)Cc2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL256933 pIC50 12.59 nM
Cc1cc(NC(=O)c2c(F)cccc2F)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL404026 pIC50 12.59 nM
Cc1cc(C(=O)Nc2ccc(CN3CCCCC3)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL480181 pIC50 12.59 nM
Cc1cc(C(=O)Nc2ccc(CN3CCCC3)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL479989 pIC50 12.59 nM
CCNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1 CHEMBL480790 pIC50 12.59 nM
CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1 CHEMBL480789 pIC50 12.59 nM
Cc1cc(NC(=O)c2ccc(CO)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL447709 pIC50 12.59 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 CHEMBL513491 pIC50 12.59 nM
O=C([O-])c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2c(F)cc(F)cc2F)n1 CHEMBL466549 pIC50 12.59 nM
COc1ccc(CCNC(=O)CN(c2cccc(C)c2C)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL392793 Log Ki 12.88 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1c(F)cccc1F CHEMBL215573 Log IC50 14.79 nM
O=C(O)Cc1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL184779 Ki 15.0 nM
Cc1ccc(-c2cccc(C(=O)O)c2)n1-c1cc(Cl)ccc1OCc1ccccc1 CHEMBL207688 Log Ki 15.49 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2Cl)n1-c1cccc(C(=O)O)c1 CHEMBL208882 Log IC50 15.85 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(OC(F)(F)F)cc2)n1-c1cccc(C(=O)O)c1 CHEMBL377910 Log IC50 15.85 nM
Cc1ccc(-c2cc(Br)ccc2OCC2CCCC2)n1-c1cccc(C(=O)O)c1 CHEMBL208684 Log IC50 15.85 nM
Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2cc(N)c(C)c(C(=O)O)c2)c1 CHEMBL388510 Log IC50 15.85 nM
Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2ccc(F)c(C(=O)O)c2)c1 CHEMBL230873 Log IC50 15.85 nM
CS(=O)(=O)c1ccc(OCc2ccc(F)cc2F)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL234710 Log IC50 15.85 nM
CSc1ccc(OCc2ccc(F)cc2F)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL234709 Log IC50 15.85 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C(=O)NC(C)(C)C)cc1 CHEMBL439381 Log IC50 15.85 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C(=O)N(C)C)cc1 CHEMBL233138 Log IC50 15.85 nM
O=C([O-])c1ccc(Cc2cc(Cl)ccc2OCc2ccccc2)s1 CHEMBL408367 Log Ki 15.85 nM
Cc1cc(NC(=O)C(C)(C)c2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL437796 pIC50 15.85 nM
Cc1cc(NC(=O)c2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254990 pIC50 15.85 nM
Cc1cc(NC(=O)C2CCCC2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254151 pIC50 15.85 nM
Cc1cc(NC(=O)OC(C)(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL258199 Log Ki 15.85 nM
Cc1cc(C(=O)Nc2ccc(CN(CCO)CCO)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL523216 pIC50 15.85 nM
CC(C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)c1ccccc1 CHEMBL90491 Ki 16.0 nM
O=C(O)c1csc(-n2nc(N3CCCCC3)c3ccccc32)n1 CHEMBL3127173 IC50 16.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3c2CCCC3)n1 CHEMBL3127177 IC50 16.0 nM
CN(CCc1ccccc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL92539 Ki 17.0 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1cccc(Br)c1 CHEMBL387454 Log IC50 17.78 nM
CC(C)(Cc1ccccc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL315391 Ki 18.0 nM
Nc1ccc2c(-c3ccccc3)nn(-c3nc(C(=O)O)cs3)c2c1 CHEMBL3127161 IC50 19.0 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(C(F)(F)F)cc1 CHEMBL238727 Log Ki 19.05 nM
Cc1ccccc1COc1ccc(Br)cc1-c1ccc(C)n1-c1cccc(C(=O)O)c1 CHEMBL208797 Log IC50 19.95 nM
Cc1ccc(-c2ccccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL211776 Log IC50 19.95 nM
O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(F)cc3)CCC2)c1 CHEMBL395284 Log IC50 19.95 nM
CNC(=O)c1cccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1 CHEMBL231722 Log IC50 19.95 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(S(N)(=O)=O)cc1 CHEMBL393187 Log IC50 19.95 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(S(C)(=O)=O)cc1 CHEMBL232930 Log IC50 19.95 nM
COc1ccc(NCc2nnc(CN(c3cccc(Cl)c3C)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL233356 Log IC50 19.95 nM
COc1ccc(Cc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(Cl)cc3)o2)cc1 CHEMBL233134 Log IC50 19.95 nM
CC(C)Cc1cn(-c2cccc(C(=O)[O-])n2)c2cc(Cl)ccc12 CHEMBL254763 Log Ki 19.95 nM
Cc1cc(NC(=O)Cc2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL257138 pIC50 19.95 nM
O=C([O-])c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 CHEMBL467579 pIC50 19.95 nM
O=C(O)c1ccccc1-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1 CHEMBL456707 pIC50 19.95 nM
O=C(O)c1cccc(-c2ccccc2-c2ccccc2OCc2ccccc2)c1 CHEMBL516787 pIC50 19.95 nM
Cc1cc(C(=O)NCC2CCNCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915256 pIC50 19.95 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3oc4ccccc4c32)n1 CHEMBL3092132 IC50 20.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c(Br)c2-c2ccccc2)n1 CHEMBL3092153 IC50 20.0 nM
O=C(O)c1csc(-n2nc(-c3cccc(F)c3)c3ccccc32)n1 CHEMBL3127165 IC50 20.0 nM
O=C(CCc1ccc(Cl)cc1CN1CCC[C@H]1c1nc(C(=O)NCCCCC2CCCCC2)co1)NS(=O)(=O)C(F)(F)F CHEMBL3942394 EC50 20.0 nM
CCCCCCCCNC(=O)c1coc([C@@H]2CCCN2Cc2cc(F)ccc2CCC(=O)NS(=O)(=O)C(F)(F)F)n1 CHEMBL3896035 EC50 20.0 nM
Cc1cc(C(=O)O)nn1Cc1cc(F)ccc1OCc1ccc(Cl)cc1Cl CHEMBL385620 Log Ki 20.42 nM
CCc1ccccc1N(CC(=O)NCc1ccc(Br)cc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL240844 Log Ki 22.91 nM
N#CC(O)c1cncc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL182623 Ki 23.0 nM
CCc1ccccc1N(CC(=O)NCc1ccc(OC)cc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL234398 IC50 25.0 nM
Cc1cc(COc2ccc(Br)cc2-c2ccc(C)n2-c2cccc(C(=O)O)c2)no1 CHEMBL209746 Log IC50 25.12 nM
Cc1ccc(-c2cc(Cl)ccc2OCC2CCCC2)n1-c1cccc(C(=O)O)c1 CHEMBL380197 Log IC50 25.12 nM
O=C(O)c1cccc(-n2c(Cl)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL377338 Log IC50 25.12 nM
Cc1ccc(-c2cc(S(C)(=O)=O)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL212742 Log IC50 25.12 nM
Cc1ccc(-c2cc(F)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)c2ccccc2c1 CHEMBL397226 Log IC50 25.12 nM
O=C(O)c1cccc(C2=C(c3ccccc3OCc3ccc(F)cc3F)CCC2)c1 CHEMBL233230 Log IC50 25.12 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc2nn[nH]c2c1 CHEMBL233975 Log IC50 25.12 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)NCc2ccccc2)c1 CHEMBL233140 Log IC50 25.12 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)NCc2ccccc2)cc1 CHEMBL234176 Log IC50 25.12 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(C(O)(C(F)(F)F)C(F)(F)F)c1 CHEMBL232544 Log IC50 25.12 nM
CCc1ccccc1N(Cc1nnc(COc2ccc(OC)cc2)o1)S(=O)(=O)c1ccc(C)cc1 CHEMBL233155 Log IC50 25.12 nM
CCc1ccccc1N(CC(=O)NCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(C)cc1 CHEMBL238754 Log Ki 25.12 nM
O=C([O-])c1csc(Nc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL401768 Log IC50 25.12 nM
O=C([O-])c1nc(Cc2cc(Cl)ccc2OCc2ccccc2)cs1 CHEMBL258057 Log IC50 25.12 nM
Cc1cc(NC(=O)OCC(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL256560 pIC50 25.12 nM
Cc1cc(NC(=O)C2CCCC2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL258413 pIC50 25.12 nM
Cc1cc(NC(=O)C(F)(F)c2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL403580 pIC50 25.12 nM
Cc1cc(NC(=O)C(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254152 pIC50 25.12 nM
Cc1cc(C(=O)NCc2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254554 pIC50 25.12 nM
Cc1cc(C(=O)Nc2ccc(CNCCO)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL495107 pIC50 25.12 nM
Cc1cc(NC(=O)c2ccccc2CO)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL480002 pIC50 25.12 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2F)n1 CHEMBL466101 pIC50 25.12 nM
CCCc1cc2cc(Cl)cc(Cn3nc(C(=O)O)cc3C)c2o1 CHEMBL1915014 pIC50 25.12 nM
Cc1cc(NC(=O)C2CCN(CC(F)(F)F)CC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915260 pIC50 25.12 nM
Cc1cc(C(=O)NCC(O)C(F)(F)F)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915263 pIC50 25.12 nM
CC1(C)C(=O)[C@H](C/C=C\CCCC(=O)O)[C@@H](/C=C/C(O)CCc2ccccc2)[C@@H]1O CHEMBL3946494 EC50 27.0 nM
O=C(O)c1cccc(-c2cnccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL210268 Log Ki 28.18 nM
O=C(O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL207174 Log Ki 28.84 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(Br)cc1 CHEMBL392794 Log Ki 28.84 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c(F)c2-c2ccccc2)n1 CHEMBL3092151 IC50 30.0 nM
O=C(O)c1csc(-n2nc(-c3ccsc3)c3ccccc32)n1 CHEMBL3127171 IC50 30.0 nM
COc1ccc(CCNC(=O)CN(c2cccc(C(F)(F)F)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL238725 Log Ki 30.9 nM
O=C(NNC(=O)C(F)(F)C(O)c1ccccn1)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL345797 pA2 31.62 nM
Cc1ccc(-c2cc(C(F)(F)F)ccc2OCC2CCCCC2)n1-c1cccc(C(=O)O)c1 CHEMBL378226 Log IC50 31.62 nM
CSc1ccc(OCc2ccc(F)cc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL389596 Log IC50 31.62 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1ccc(S(C)(=O)=O)cc1 CHEMBL232931 Log IC50 31.62 nM
COc1ccc(Nc2nnc(CN(c3cccc(Cl)c3C)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL233545 Log IC50 31.62 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(C#N)cc1 CHEMBL238929 Log Ki 31.62 nM
CCCc1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL255880 Log IC50 31.62 nM
CC(C)(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL254764 Log IC50 31.62 nM
Cc1cc(NC(=O)OC(C)(C)C)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL402770 pIC50 31.62 nM
Cc1cc(NC(=O)C2CCCCC2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL258200 pIC50 31.62 nM
Cc1cc(C(=O)Nc2ccc(CO)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL495294 pIC50 31.62 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCC2CCCC2)n1 CHEMBL511252 pIC50 31.62 nM
CC1CCN(c2nn(-c3nc(C(=O)O)cs3)c3ccccc23)CC1 CHEMBL3127174 IC50 32.0 nM
COc1ccc(CCNC(=O)CN(c2cccc(Br)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL238514 Log Ki 34.67 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccc(C(F)(F)F)cc1 CHEMBL215956 Log IC50 35.48 nM
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COc2ccccc2)[C@H](O)C[C@@H]1O CHEMBL334398 IC50 38.0 nM
COc1ccc(CCNC(=O)CN(c2ccccc2C)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL241493 Log Ki 38.9 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccncc32)n1 CHEMBL3127152 IC50 39.0 nM
O=C(CCSCc1ccco1)NCC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL436218 pA2 39.81 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(C(F)(F)F)cc2)n1-c1cccc(C(=O)O)c1 CHEMBL379514 Log IC50 39.81 nM
Cc1ccc(-c2cc(Cl)ccc2OCC2CCCO2)n1-c1cccc(C(=O)O)c1 CHEMBL378090 Log IC50 39.81 nM
Cc1ccc(-c2cc(Cl)ccc2OCC2CCOCC2)n1-c1cccc(C(=O)O)c1 CHEMBL212680 Log IC50 39.81 nM
Cc1ccc(-c2cc(Br)ccc2OCC2CCCCC2)n1-c1cccc(C(=O)O)c1 CHEMBL210987 Log IC50 39.81 nM
O=C(O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)cnn1 CHEMBL233044 Log IC50 39.81 nM
O=C(O)c1cc(C2=C(c3cc(C(F)(F)F)ccc3OCc3ccccc3)CCC2)ccn1 CHEMBL234290 Log IC50 39.81 nM
N#Cc1ccc(OCc2ccc(F)cc2F)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL397957 Log IC50 39.81 nM
COc1ccc(COc2ccc(Br)cc2C2=C(c3cccc(C(=O)O)c3)CCC2)cc1 CHEMBL234280 Log IC50 39.81 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(-c2cnc[nH]2)cc1 CHEMBL233565 Log IC50 39.81 nM
Cc1nnc(-c2cccc(-n3c(C)ccc3-c3cc(Br)ccc3OCc3ccc(F)cc3F)c2)o1 CHEMBL233160 Log IC50 39.81 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc2[nH]ncc2c1 CHEMBL392047 Log IC50 39.81 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc2cn[nH]c2c1 CHEMBL234181 Log IC50 39.81 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)N[C@H](C)c2ccccc2)c1 CHEMBL391931 Log IC50 39.81 nM
CCOc1ccc(Cc2nnc(CN(c3ccccc3CC)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL232159 Log Ki 39.81 nM
COc1ccc(Nc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL391270 Log IC50 39.81 nM
CC(C)COc1ccc(Cl)cc1Cc1cccc(C(=O)O)n1 CHEMBL403329 Log IC50 39.81 nM
O=C([O-])c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL256674 Log IC50 39.81 nM
CC(C)COc1ccc(Cl)cc1Cc1cccc(C(=O)[O-])n1 CHEMBL257998 Log IC50 39.81 nM
CC(C)c1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL403890 Log IC50 39.81 nM
Cc1c(CC(C)C)c2ccc(Cl)cc2n1-c1nc(C(=O)[O-])cs1 CHEMBL403082 Log IC50 39.81 nM
CC(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2ccc(Cl)cc12 CHEMBL256334 Log IC50 39.81 nM
CC(C)Cc1cn(-c2nc(C(=O)[O-])cs2)c2cc(F)ccc12 CHEMBL257135 Log IC50 39.81 nM
Cc1cc(NC(=O)C(F)(F)c2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254558 pIC50 39.81 nM
Cc1cc(NC(=O)Cc2cccnc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL257544 pIC50 39.81 nM
Cc1cc(NC(=O)C2CCOC2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL403940 pIC50 39.81 nM
Cc1cc(NC(=O)C2CCCO2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL256731 pIC50 39.81 nM
Cc1cc(C(=O)NCc2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL257146 pIC50 39.81 nM
Cc1cc(C(=O)Nc2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL404698 pIC50 39.81 nM
Cc1cc(NC(=O)c2ccc3c(c2)CCNC3)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL493254 pIC50 39.81 nM
Cc1cc(NC(=O)c2ccc(CN3CCCCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL492829 pIC50 39.81 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2Cl)n1 CHEMBL466103 pIC50 39.81 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2)n1 CHEMBL467113 pIC50 39.81 nM
O=C([O-])c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2F)n1 CHEMBL459537 pIC50 39.81 nM
Cc1cc(NC(=O)C2(F)CCNCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915259 pIC50 39.81 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccc(N4CCC4)nc32)n1 CHEMBL4126096 IC50 40.0 nM
O=C(CCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL90227 Ki 47.0 nM
O=C(CCc1ccc(F)cc1CN1CCC[C@H]1c1nc(C(=O)NCCCCC2CCCCC2)co1)NS(=O)(=O)C(F)(F)F CHEMBL3972583 EC50 47.0 nM
CO[C@@](C(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)(c1ccccc1)C(F)(F)F CHEMBL91537 Ki 50.0 nM
Cc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1-c1ccccc1 CHEMBL2442495 IC50 50.0 nM
Cc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1-c1cccc(F)c1 CHEMBL3092140 IC50 50.0 nM
CNc1ccc2c(-c3ccccc3)nn(-c3nc(C(=O)O)cs3)c2c1 CHEMBL3127162 IC50 50.0 nM
COc1ccc(COc2ccc(Br)cc2-c2ccc(C)n2-c2cccc(C(=O)O)c2)cc1 CHEMBL377034 Log IC50 50.12 nM
COc1cccc(COc2ccc(Br)cc2-c2ccc(C)n2-c2cccc(C(=O)O)c2)c1 CHEMBL377134 Log IC50 50.12 nM
O=C(O)c1cccc(C2=C(c3ccccc3OCc3ccc(Cl)cc3F)CCC2)c1 CHEMBL388655 Log IC50 50.12 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)NCc2ccccn2)c1 CHEMBL399800 Log IC50 50.12 nM
CCN(CC)C(=O)c1ccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)cc1 CHEMBL234174 Log IC50 50.12 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3ccc(C(F)(F)F)cc3)o2)c2cccc(Cl)c2C)cc1 CHEMBL232389 Log IC50 50.12 nM
O=C([O-])Cc1csc(-c2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL404760 Log IC50 50.12 nM
CC(C)Cc1cn(-c2ccc(C(=O)[O-])s2)c2cc(Cl)ccc12 CHEMBL402608 Log IC50 50.12 nM
Cc1cc(NC(=O)OC(C)(C)C(F)(F)F)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL255876 pIC50 50.12 nM
Cc1cc(NC(=O)OC(C)C)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL258183 pIC50 50.12 nM
Cc1cc(NC(=O)Cc2ccncc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL404481 pIC50 50.12 nM
Cc1cc(C(=O)NCc2cccnc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254553 pIC50 50.12 nM
CCN1CCc2ccc(C(=O)Nc3cc(C)n(Cc4cc(Cl)ccc4OCC(C)C)n3)cc2CC1 CHEMBL495091 pIC50 50.12 nM
Cc1cc(NC(=O)c2ccc(C(C)N3CCCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL494269 pIC50 50.12 nM
Cc1cc(NC(=O)c2ccc(C(C)NCC(C)C)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL494268 pIC50 50.12 nM
Cc1cc(NC(=O)c2ccc(CN3CCOCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL521988 pIC50 50.12 nM
Cc1cc(NC(=O)c2ccc(CN3CCCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL481689 pIC50 50.12 nM
O=C([O-])c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(Br)cc2F)n1 CHEMBL467578 pIC50 50.12 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C3CC3)oc12 CHEMBL1915013 pIC50 50.12 nM
Cc1cc(-c2nc3ccccc3[nH]2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 CHEMBL1915245 pIC50 50.12 nM
Cc1cc(C(=O)NN2CCOCC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 CHEMBL1915251 pIC50 50.12 nM
O=S(=O)(Cc1ccccc1)Nc1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL182662 Ki 52.0 nM
O=C(O)c1cccc(-c2cccnc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL207395 Log Ki 52.48 nM
O=C(Cc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL328067 Ki 57.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c(O)c2-c2ccccc2)n1 CHEMBL3092155 IC50 60.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c(Cl)c2-c2ccccc2)n1 CHEMBL3092152 IC50 60.0 nM
COc1ccc(CCNC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL238513 Log Ki 61.66 nM
COc1ccc(CCNC(=O)CN(c2cccc(C)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL238512 Log Ki 61.66 nM
CCc1ccccc1N(CC(=O)OCc1ccc(OC)cc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL234600 IC50 63.0 nM
O=C(CCc1cc2c(cc1CN1CCC[C@H]1c1nc(C(=O)NCCCCC3CCCCC3)co1)OCO2)NS(=O)(=O)C(F)(F)F CHEMBL3967284 EC50 63.0 nM
O=C(CCSCc1ccco1)CNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL352251 pA2 63.1 nM
CSc1ccc(OCc2ccccc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL234281 Log IC50 63.1 nM
Cc1cc(=O)[nH]c2cc(-n3c(C)ccc3-c3cc(Cl)ccc3OCc3ccccc3)ccc12 CHEMBL438126 Log IC50 63.1 nM
CC(=O)Nc1cccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL233361 Log IC50 63.1 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(-c2nc3ccccc3[nH]2)c1 CHEMBL233159 Log IC50 63.1 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)NCc2ccncc2)c1 CHEMBL233146 Log IC50 63.1 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)NCc2cccnc2)c1 CHEMBL233141 Log IC50 63.1 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(N)=O)c1 CHEMBL393416 Log IC50 63.1 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(C(=O)NCc2ccncc2)cc1 CHEMBL232537 Log IC50 63.1 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3ccc(Cl)cc3Cl)o2)c2cccc(Cl)c2C)cc1 CHEMBL232926 Log IC50 63.1 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3c(Cl)cccc3Cl)o2)c2cccc(Cl)c2C)cc1 CHEMBL232925 Log IC50 63.1 nM
COc1ccc(Cc2nnc(CN(c3cccc(C(F)(F)F)c3C)S(=O)(=O)c3ccc(C)cc3)o2)cc1 CHEMBL232160 Log IC50 63.1 nM
CCc1ccccc1N(CC(=O)NCc1ccccc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL410957 Log Ki 63.1 nM
O=C([O-])c1csc(-n2cc(Cc3ccccc3)c3ccc(Cl)cc32)n1 CHEMBL436656 Log Ki 63.1 nM
Cc1cc(NC(=O)OC2CCOCC2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL255701 pIC50 63.1 nM
Cc1cc(NC(=O)C(C)(C)c2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254559 pIC50 63.1 nM
Cc1cc(NC(=O)C2CCOCC2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL403939 pIC50 63.1 nM
O=C([O-])c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 CHEMBL512617 pIC50 63.1 nM
O=C(O)c1cc(F)cc(-c2ccccc2-c2ccccc2OCc2ccccc2)c1 CHEMBL514425 pIC50 63.1 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C(C)(C)C)oc12 CHEMBL1915016 pIC50 63.1 nM
CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)cc4cc(C(C)C)oc34)n2)cc1 CHEMBL1915246 pIC50 63.1 nM
Cc1cc(C(=O)NC2CCOCC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 CHEMBL1915247 pIC50 63.1 nM
Cc1cc(NC(=O)CC2CCNCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915257 pIC50 63.1 nM
COc1ccc(CCNC(=O)CN(c2ccccc2C)S(=O)(=O)c2ccc(C)cc2)c(F)c1OC CHEMBL400423 Log Ki 66.07 nM
COc1ccccc1COc1ccc(Br)cc1Cn1nc(C(=O)O)cc1C CHEMBL212300 Log Ki 69.18 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 CHEMBL238930 Log Ki 69.18 nM
COc1ccc(CCC(=O)NS(=O)(=O)C(F)(F)F)c(CN2CCC[C@H]2c2nc(C(=O)NCCCCC3CCCCC3)co2)c1 CHEMBL3904989 EC50 70.0 nM
CCn1nccc1N(CC(=O)NCc1ccc(Cl)cc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL240029 Log Ki 72.44 nM
O=C(O)c1cccc(-c2ccncc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL209244 Log IC50 79.43 nM
O=C1OCC(c2cc(Cl)ccc2OCc2ccccc2)=C1c1cccc(C(=O)O)c1 CHEMBL208030 Log IC50 79.43 nM
O=C(O)c1cccc(-n2nccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL380667 Log IC50 79.43 nM
Cc1ccc(-c2cc(Br)ccc2OCc2cccc(OC(F)F)c2)n1-c1cccc(C(=O)O)c1 CHEMBL210994 Log IC50 79.43 nM
CCc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL379155 Log IC50 79.43 nM
Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2cc(C(=O)O)c3ccccc3c2)c1 CHEMBL269514 Log IC50 79.43 nM
CS(=O)(=O)c1ccc(OCc2ccc(F)cc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL395311 Log IC50 79.43 nM
CS(=O)(=O)c1ccc(OCc2ccccc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL265086 Log IC50 79.43 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(S(=O)(=O)NC(=O)c2ccccc2)c1 CHEMBL394173 Log IC50 79.43 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3ccccc3Cl)o2)c2cccc(Cl)c2C)cc1 CHEMBL232531 Log IC50 79.43 nM
CCc1ccccc1N(CC(=O)NCc1cccc(OC)c1)S(=O)(=O)c1ccc(C)cc1 CHEMBL240247 Log Ki 79.43 nM
O=C([O-])c1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL403460 Log IC50 79.43 nM
Cc1cc(NC(=O)O[C@H]2CCOC2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL429321 pIC50 79.43 nM
CCOC(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL258226 pIC50 79.43 nM
Cc1cc(NC(=O)OCc2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL253538 pIC50 79.43 nM
Cc1cc(NC(=O)OCc2ccccc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254963 pIC50 79.43 nM
Cc1cc(C(=O)NCc2ccncc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL256736 pIC50 79.43 nM
Cc1cc(C(=O)Nc2ccc(F)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL256579 pIC50 79.43 nM
Cc1cc(NC(=O)c2ccc3c(c2)CCNCC3)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL495090 pIC50 79.43 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2F)n1 CHEMBL508276 pIC50 79.43 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2c(F)cc(F)cc2F)n1 CHEMBL466102 pIC50 79.43 nM
O=C(O)c1ccc(F)c(-c2ccccc2-c2ccccc2OCc2ccccc2)c1 CHEMBL459091 pIC50 79.43 nM
Cc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1-c1ccsc1 CHEMBL3092135 IC50 80.0 nM
O=C(O)c1csc(-n2nc(C3=CCCC3)c3ccccc32)n1 CHEMBL3127169 IC50 80.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3cc(F)ccc32)n1 CHEMBL3127155 IC50 80.0 nM
O=C(CCc1ccccc1-c1ccccc1CSCCc1ccccc1)NS(=O)(=O)c1cccs1 CHEMBL431612 Ki 83.0 nM
Cc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1C(F)(F)F CHEMBL2442494 IC50 84.0 nM
CC#CCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3753268 Ki 89.0 nM
Cc1ccc(S(=O)(=O)N(CC(=O)NCCc2ccc(NS(C)(=O)=O)cc2)c2ccccc2C)cc1 CHEMBL241670 Log Ki 89.13 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](CCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3806130 EC50 97.0 nM
O=C(NCCc1cccs1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL328697 Ki 100.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cccc2C(F)(F)F)n1-c1cccc(C(=O)O)c1 CHEMBL208891 Log IC50 100.0 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(Cl)c(Cl)c2)n1-c1cccc(C(=O)O)c1 CHEMBL378464 Log IC50 100.0 nM
CCc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL379143 Log IC50 100.0 nM
O=C(O)c1cccc(-n2c(-c3cc(Cl)ccc3OCc3ccc(F)cc3F)ccc2C(F)(F)F)c1 CHEMBL208660 Log IC50 100.0 nM
N#Cc1ccc(OCc2ccccc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL234924 Log IC50 100.0 nM
O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(Cl)c(Cl)c3)CCC2)c1 CHEMBL234069 Log IC50 100.0 nM
COc1ccc(COc2ccccc2C2=C(c3cccc(C(=O)O)c3)CCC2)cc1 CHEMBL233858 Log IC50 100.0 nM
CCc1ccccc1N(Cc1nnc(Oc2ccc(OC)cc2)o1)S(=O)(=O)c1ccc(C)cc1 CHEMBL391268 Log Ki 100.0 nM
CC(C)Cc1cn(-c2ncc(C(=O)[O-])s2)c2cc(Cl)ccc12 CHEMBL401698 Log IC50 100.0 nM
CC(C)C(=O)c1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL404309 Log IC50 100.0 nM
CNC(=O)c1cc(C)n(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL258171 pIC50 100.0 nM
Cc1cc(NC(=O)c2ccc3c(c2)CCN(C(C)C)C3)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL492840 pIC50 100.0 nM
Cc1cc(NC(=O)c2ccc(C3CCCN3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL494466 pIC50 100.0 nM
Cc1cc(NC(=O)c2ccc(CN(C)C)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL481519 pIC50 100.0 nM
CCNCc1ccc(C(=O)Nc2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1 CHEMBL481870 pIC50 100.0 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2)n1 CHEMBL511733 pIC50 100.0 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCC2CCCCC2)n1 CHEMBL468723 pIC50 100.0 nM
Cc1cccc(-c2cc(Cl)ccc2OCc2ccccc2)c1-c1cccc(C(=O)[O-])c1 CHEMBL458008 pIC50 100.0 nM
CCCCOc1ccc(Cl)cc1-c1ccccc1-c1cccc(C(=O)[O-])n1 CHEMBL499155 pIC50 100.0 nM
Cc1cc(C(=O)NN2CCCCC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 CHEMBL1915250 pIC50 100.0 nM
Cc1cc(NC(=O)C2CCNCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 CHEMBL1915258 pIC50 100.0 nM
Cc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1-c1ccc(F)cc1 CHEMBL3092141 IC50 100.0 nM
CCOc1ccc2c(-c3ccccc3)nn(-c3nc(C(=O)O)cs3)c2c1 CHEMBL3127160 IC50 100.0 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1cccc(Cl)c1 CHEMBL215667 Log IC50 114.82 nM
O=C(NCCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL90269 Ki 120.0 nM
Cc1c(-c2ccccc2)nn(-c2nc(C(=O)O)cs2)c1-c1cccs1 CHEMBL3092134 IC50 120.0 nM
O=C(O)c1csc(-n2cc(-c3ccccc3)c3ccccc32)n1 CHEMBL3127176 IC50 120.0 nM
CCCCC(C)(C)[C@H](O)/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL3753853 Ki 120.0 nM
O=C(O)c1nn(Cc2cc(Br)ccc2OCc2ccccc2)cc1F CHEMBL213669 Log IC50 123.03 nM
Cc1ccc(-c2cc(Cl)ccc2OCC2CCCCC2)n1-c1cccc(C(=O)O)c1 CHEMBL377831 Log IC50 125.89 nM
Cc1cccc(COc2ccc(Br)cc2Cn2nc(C(=O)O)cc2C)c1 CHEMBL212667 Log IC50 125.89 nM
CCOc1ccc(C(=O)O)cc1-n1c(C)ccc1-c1cc(Cl)ccc1OCc1ccccc1 CHEMBL233872 Log IC50 125.89 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(-c2ncccn2)c1 CHEMBL393743 Log IC50 125.89 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(-c2cccnc2)c1 CHEMBL234182 Log IC50 125.89 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(S(C)(=O)=O)c1 CHEMBL232733 Log IC50 125.89 nM
CCc1ccccc1N(Cc1nnc(Cc2ccc(OC)cc2)o1)S(=O)(=O)c1ccc(C)cc1 CHEMBL232158 Log IC50 125.89 nM
CCc1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL404176 Log IC50 125.89 nM
Cc1cc(C(N)=O)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL256737 pIC50 125.89 nM
Cc1cc(C(=O)Nc2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL257147 pIC50 125.89 nM
Cc1cc(C(=O)NC(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL257970 pIC50 125.89 nM
Cc1cc(C(N)=O)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL437399 pIC50 125.89 nM
Cc1cc(NC(=O)c2cccc(CN3CCCC3)c2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL481137 pIC50 125.89 nM
O=C(O)c1cc(-c2ccccc2-c2ccccc2OCc2ccccc2)ccc1Cl CHEMBL457797 pIC50 125.89 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cn2cc(C(C)C)cc12 CHEMBL1915018 pIC50 125.89 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c(I)c2-c2ccccc2)n1 CHEMBL3092154 IC50 130.0 nM
CCc1ccccc1N(CC(=O)NCc1ccccc1F)S(=O)(=O)c1ccc(C)cc1 CHEMBL401042 Log Ki 134.9 nM
C[C@H](NC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)c1ccccc1 CHEMBL327597 Ki 140.0 nM
O=C(COc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL432380 Ki 140.0 nM
O=C(O)c1csc(-n2nc(-c3ccc(C(F)(F)F)cc3)c3ccccc32)n1 CHEMBL3127168 IC50 140.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3ccc(O)cc32)n1 CHEMBL3127158 IC50 140.0 nM
CS(=O)(=O)c1cc(F)cc2c1c(C(=O)c1ccc(Cl)cc1)c1n2CCC[C@@H]1CC(=O)O CHEMBL412070 Ki 142.0 nM
CC(C)(C)CCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3752435 Ki 149.0 nM
O=C(NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1)OCc1ccccc1 CHEMBL91063 Ki 150.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c(C(F)(F)F)c2-c2ccccc2)n1 CHEMBL3092150 IC50 150.0 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(=O)O)ccc1Cl CHEMBL395756 Log IC50 158.49 nM
O=C(O)c1ccnc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)n1 CHEMBL234939 Log IC50 158.49 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc2c(c1)C(=O)NC2=O CHEMBL233772 Log IC50 158.49 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3cccc(Cl)c3)o2)c2cccc(Cl)c2C)cc1 CHEMBL232924 Log IC50 158.49 nM
O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL270174 Log IC50 158.49 nM
Cc1cc(C(=O)O)cn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL403459 Log IC50 158.49 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL258041 Log IC50 158.49 nM
CC(C)Cc1cn(-c2nc(CC(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL257413 Log IC50 158.49 nM
O=C(Cc1ccccc1)Nc1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL257969 pIC50 158.49 nM
O=C([O-])c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCC2CCCC2)n1 CHEMBL458858 pIC50 158.49 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/CCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805176 EC50 160.0 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccccc1C CHEMBL238931 Log Ki 165.96 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(OC)cc1 CHEMBL239137 Log Ki 169.82 nM
COc1ccc(CCNC(=O)CN(c2ccccc2C)S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL400422 Log Ki 169.82 nM
O=C(O)c1csc(-n2nc(-c3ccccc3O)cc2C(F)(F)F)n1 CHEMBL2442490 IC50 180.0 nM
O=C(O)c1cc(-c2cccs2)n(Cc2cc(Br)ccc2OCc2ccccc2)n1 CHEMBL214900 Log IC50 194.98 nM
Cc1noc(C)c1COc1ccc(Br)cc1-c1ccc(C)n1-c1cccc(C(=O)O)c1 CHEMBL212679 Log IC50 199.53 nM
O=C(O)c1cccc(-n2c(-c3cc(Cl)ccc3OCc3ccc(F)cc3)ccc2C(F)(F)F)c1 CHEMBL209326 Log IC50 199.53 nM
O=C(O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)ncn1 CHEMBL389994 Log IC50 199.53 nM
N#Cc1ccc(OCc2ccc(Cl)cc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL234289 Log IC50 199.53 nM
Cc1nc(-c2cccc(-n3c(C)ccc3-c3cc(Br)ccc3OCc3ccc(F)cc3F)c2)no1 CHEMBL233359 Log IC50 199.53 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cccc(S(C)(=O)=O)c1 CHEMBL232734 Log IC50 199.53 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3ccc(F)cc3)o2)c2cccc(Cl)c2C)cc1 CHEMBL393376 Log IC50 199.53 nM
Cc1ccc(S(=O)(=O)N(CC(=O)NCc2ccc(Cl)cc2)c2cccnc2C)cc1 CHEMBL240866 Log Ki 199.53 nM
COC(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL258439 pIC50 199.53 nM
Cc1cc(C(=O)NN2CCCCC2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL256532 pIC50 199.53 nM
Cc1cc(C(=O)Nc2cccc(F)c2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL254958 pIC50 199.53 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCC2CC2)n1 CHEMBL511919 pIC50 199.53 nM
O=C(NCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL90226 Ki 200.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3cccnc32)n1 CHEMBL3127151 IC50 200.0 nM
Cc1ccc(S(=O)(=O)N(CC(=O)NCCc2cccc(O)c2)c2ccccc2C)cc1 CHEMBL241494 Log Ki 204.17 nM
CCc1ccccc1N(CC(=O)NCc1ccc(C(F)(F)F)cc1)S(=O)(=O)c1ccc(C)cc1 CHEMBL240457 Log Ki 208.93 nM
CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)C[C@H]1O CHEMBL815 IC50 220.0 nM
CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL91270 Ki 220.0 nM
CCCCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3753221 Ki 220.0 nM
O=C(O)CCCCCC[C@@H]1[C@@H](c2ccc3c(c2)CCC3)[C@H](O)C[C@H]1Cl CHEMBL3976116 EC50 221.0 nM
O=C(O)c1ccc(CCCc2ccccc2OCc2ccccc2)cc1 CHEMBL124199 Ki 230.0 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1cccc(C#N)c1 CHEMBL392795 Log Ki 239.88 nM
Cc1ccc(-c2cc(Br)ccc2OCc2cccc(C(F)(F)F)c2)n1-c1cccc(C(=O)O)c1 CHEMBL376996 Log IC50 251.19 nM
COc1ccc(C(=O)O)cc1-n1c(C)ccc1-c1cc(Cl)ccc1OCc1ccccc1 CHEMBL233871 Log IC50 251.19 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(-c2ccccn2)c1 CHEMBL234183 Log IC50 251.19 nM
Cc1ccc(S(=O)(=O)N(CC(=O)NCCc2ccc(Cl)cc2)c2ccccc2C)cc1 CHEMBL231699 Log IC50 251.19 nM
CCc1ccccc1N(CC(=O)NCc1cccc(Cl)c1)S(=O)(=O)c1ccc(C)cc1 CHEMBL393178 Log Ki 251.19 nM
O=C([O-])c1csc(-n2cc(CC(F)(F)F)c3ccc(Cl)cc32)n1 CHEMBL256336 Log IC50 251.19 nM
O=C(Nc1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1)c1ccccc1 CHEMBL255485 pIC50 251.19 nM
Cc1cc(C(=O)NN2CCOCC2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL402202 pIC50 251.19 nM
Cc1cc(NC(=O)c2cccc(CN3CCOCC3)c2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL520950 pIC50 251.19 nM
CCCOc1ccc(Cl)cc1-c1ccccc1-c1cccc(C(=O)[O-])n1 CHEMBL456679 pIC50 251.19 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2oc(C(C)C)cc12 CHEMBL1915017 pIC50 251.19 nM
OC(c1cncc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1)(C(F)(F)F)C(F)(F)F CHEMBL182367 Ki 260.0 nM
CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)O)c3C[C@H]2C[C@H]1O CHEMBL1237119 EC50 285.0 nM
CC1(C)C(=O)[C@H](C/C=C\CCCC(=O)O)[C@@H](/C=C/C(O)Cc2ccccc2)[C@@H]1O CHEMBL3964563 IC50 290.0 nM
CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)C[C@H]1O CHEMBL40183 EC50 300.0 nM
CC1(C)C(=O)[C@H](C/C=C\CCCC(=O)O)[C@@H](/C=C/C(O)Cc2cc3ccccc3s2)[C@@H]1O CHEMBL3922155 IC50 308.0 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1cccc(C(F)(F)F)c1 CHEMBL425076 Log IC50 309.03 nM
O=C(CCc1ccncc1)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL155358 pA2 316.23 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)ccc1Cl CHEMBL233665 Log IC50 316.23 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)N[C@@H](C)c2ccccc2)c1 CHEMBL391228 Log IC50 316.23 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3cccc(F)c3)o2)c2cccc(Cl)c2C)cc1 CHEMBL400025 Log IC50 316.23 nM
CCc1ccccc1N(Cc1nnc(Cc2ccc(Cl)cc2)o1)S(=O)(=O)c1ccc(C)cc1 CHEMBL401432 Log Ki 316.23 nM
O=C([O-])c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL404239 Log IC50 316.23 nM
Cn1cc(C(=O)O)nc1Cc1cc(Cl)ccc1OCc1ccccc1 CHEMBL535640 Log IC50 316.23 nM
CC(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL402604 pIC50 316.23 nM
O=C(O)c1cccc(-c2ccccc2-c2ccc(Cl)cc2OCc2ccccc2)c1 CHEMBL460168 pIC50 316.23 nM
CO[C@H]1CC[C@H](NC(=O)c2cc(C)n(Cc3cc(Cl)cc4cc(C(C)C)oc34)n2)CC1 CHEMBL1915248 pIC50 316.23 nM
O=C(O)c1csc(-n2nc(-c3ccc(O)cc3)cc2C(F)(F)F)n1 CHEMBL2442488 IC50 320.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)cc2C(F)(F)F)n1 CHEMBL1479261 IC50 320.0 nM
Cc1sc(-n2nc(-c3ccccc3)c(C)c2-c2ccccc2)nc1C(=O)O CHEMBL3092147 IC50 330.0 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1cccc([N+](=O)[O-])c1 CHEMBL379151 Log Ki 338.84 nM
CN(C(=O)NCCc1ccccc1)S(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL327596 Ki 360.0 nM
Cc1cn(Cc2ccc3ccccc3c2)c2c(/C=C/C(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 CHEMBL565799 IC50 360.0 nM
O=C(O)CCCCCC[C@@H]1[C@@H](CCC(O)CSc2cccc(F)c2)[C@H](O)C[C@@H]1O CHEMBL173499 IC50 364.0 nM
O=C(O)c1cccc(-c2nccnc2-c2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL207175 Log IC50 398.11 nM
Cc1ccc(-c2cc(-c3ccccc3)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL377245 Log IC50 398.11 nM
N#Cc1ccc(OCc2ccc(F)cc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 CHEMBL234082 Log IC50 398.11 nM
O=C(O)c1cccc(C2=C(c3ccccc3OCc3ccc(Cl)c(Cl)c3)CCC2)c1 CHEMBL233231 Log IC50 398.11 nM
CCc1ccccc1N(Cc1nnc(Cc2ccccc2)o1)S(=O)(=O)c1ccc(C)cc1 CHEMBL231964 Log Ki 398.11 nM
Cc1ccc(S(=O)(=O)N(CC(=O)NCc2ccc(Cl)cc2)c2ccnn2C)cc1 CHEMBL240028 Log Ki 398.11 nM
O=C(Cc1ccccn1)Nc1ccn(Cc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL402326 pIC50 398.11 nM
O=C(NCCCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL90935 Ki 400.0 nM
Cc1cn(Cc2cc(Br)ccc2OCc2ccccc2)nc1C(=O)O CHEMBL380297 Log IC50 426.58 nM
CCc1ccccc1N(CC(=O)NCc1cccc(OC(F)(F)F)c1)S(=O)(=O)c1ccc(C)cc1 CHEMBL240248 Log Ki 426.58 nM
COc1ccc(-c2cc(C(F)(F)F)n(-c3nc(C(=O)O)cs3)n2)cc1 CHEMBL2442486 IC50 430.0 nM
CC(C)(CCCCF)[C@H](O)/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL3752406 Ki 431.0 nM
O=C(O)c1nn(Cc2cc(Br)ccc2OCc2ccccc2)cc1Br CHEMBL215690 Log IC50 457.09 nM
O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COc2cccc(Cl)c2)[C@H](O)C[C@@H]1O CHEMBL37853 IC50 496.0 nM
Cn1c(-c2ccccc2)nc(-c2nc(C(=O)O)cs2)c1-c1ccccc1 CHEMBL2442497 IC50 500.0 nM
Cc1c(-c2ccccc2)nn(-c2nc(/C=C/C(=O)O)cs2)c1-c1ccccc1 CHEMBL3092148 IC50 500.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3c(F)cccc32)n1 CHEMBL3127154 IC50 500.0 nM
Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(-n2cncn2)cc1 CHEMBL391456 Log IC50 501.19 nM
Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cccc(C(=O)Nc2ccccc2)c1 CHEMBL391930 Log IC50 501.19 nM
Cc1ccc(-c2ccccc2OCc2ccc(F)cc2F)n1-c1cccc(C(N)=O)c1 CHEMBL393374 Log IC50 501.19 nM
Cc1ccc(-c2ccccc2OCc2ccccc2)n1-c1ccc(S(C)(=O)=O)cc1 CHEMBL439388 Log IC50 501.19 nM
CCc1ccccc1N(Cc1nnc(CNc2ccc(OC)cc2)o1)S(=O)(=O)c1ccc(C)cc1 CHEMBL233157 Log IC50 501.19 nM
Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3ccccc3F)o2)c2cccc(Cl)c2C)cc1 CHEMBL233808 Log IC50 501.19 nM
Cc1cc(NC(=O)c2cccc(CN3CCCCC3)c2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL482132 pIC50 501.19 nM
CCNCc1cccc(C(=O)Nc2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)c1 CHEMBL516608 pIC50 501.19 nM
Cc1c(C(=O)O)cccc1-c1ccccc1-c1ccccc1OCc1ccccc1 CHEMBL515697 pIC50 501.19 nM
Cc1cc(C(=O)O)nn1Cc1cc(Cl)cn2cc(C(C)C)nc12 CHEMBL1915019 pIC50 501.19 nM
Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccc(Cl)c(C(F)(F)F)c1 CHEMBL215687 Log IC50 575.44 nM
O=C(O)c1csc(-n2nc(-c3cccc(O)c3)cc2C(F)(F)F)n1 CHEMBL2442489 IC50 580.0 nM
COc1ccc(CCNC(=O)CN(c2ccccc2)S(=O)(=O)c2ccc(C)cc2)cc1OC CHEMBL401452 Log Ki 588.84 nM
Cc1ccc(-c2cc(-c3ccsc3)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL379163 Log IC50 630.96 nM
Cc1ccc(-c2ccccc2OCc2ccc(F)cc2F)n1-c1ccc2nn[nH]c2c1 CHEMBL233971 Log IC50 630.96 nM
O=C([O-])c1csc(-c2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL270162 Log IC50 630.96 nM
O=C([O-])c1cncc(Cc2cc(Cl)ccc2OCc2ccccc2)c1 CHEMBL258303 Log IC50 630.96 nM
O=C([O-])c1cnc(Cc2cc(Cl)ccc2OCc2ccccc2)s1 CHEMBL257846 Log IC50 630.96 nM
CC(C)Cc1cn(-c2cccc(C(=O)[O-])c2)c2cc(Cl)ccc12 CHEMBL255928 Log IC50 630.96 nM
Cc1cc(NC(=O)c2cccc(CN(C)C)c2)nn1Cc1cc(Cl)ccc1OCC(C)C CHEMBL480979 pIC50 630.96 nM
COC(=O)CCC/C=C\C[C@H]1C(=O)C(C)(C)[C@@H](O)[C@@H]1/C=C/C(O)CCc1ccccc1 CHEMBL3928703 IC50 638.0 nM
O=C(O)c1nn(Cc2cc(Br)ccc2OCc2ccccc2)cc1CO CHEMBL214639 Log IC50 676.08 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/COc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805693 EC50 700.0 nM
CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1cccc(OC(F)(F)F)c1 CHEMBL239363 Log Ki 707.95 nM
O=C(O)CCCCCC[C@@H]1[C@@H](CC[C@@H](O)COc2ccccc2)[C@H](O)C[C@@H]1O CHEMBL425681 IC50 713.0 nM
COc1ccc(CCNC(=O)CN(c2ccccc2C)S(=O)(=O)c2ccccc2)cc1OC CHEMBL238726 Log Ki 741.31 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 CHEMBL88154 Ki 770.0 nM
CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C(=O)C(C)(C)[C@H]1O CHEMBL3895324 IC50 782.0 nM
Cc1c(Br)cc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 CHEMBL377135 Log IC50 794.33 nM
Cc1ccc(S(=O)(=O)N(CC(=O)NCc2ccc(Cl)cc2)c2ncccc2C)cc1 CHEMBL241076 Log Ki 794.33 nM
O=C(O)c1cccc(Oc2cc(Cl)ccc2OCc2ccccc2)n1 CHEMBL273145 Log IC50 794.33 nM
O=C(O)c1ccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccccc2)cc1 CHEMBL456919 pIC50 794.33 nM
Cc1cc(C(=O)NC2CCNCC2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 CHEMBL1915249 pIC50 794.33 nM
O=C(O)c1csc(SCCN2C(=O)OC[C@@H]2/C=C/[C@@H](O)C2(CCc3ccccc3)CCC2)n1 CHEMBL3753622 Ki 802.0 nM
O=C(CCc1ccccc1-c1cccc(CSCCc2ccccc2)c1)NS(=O)(=O)c1cccs1 CHEMBL86933 Ki 820.0 nM
O=C(O)CCCCCC[C@@H]1[C@@H](CCC(O)CSc2ccccc2)[C@H](O)C[C@@H]1O CHEMBL173299 IC50 912.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/CCCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805169 EC50 970.0 nM
CCCCc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1ccccc1 CHEMBL212563 Log Ki 977.24 nM
CN(C)C(=O)c1cn(-c2nc(C(=O)[O-])cs2)c2cc(Cl)ccc12 CHEMBL255319 Log IC50 1000.0 nM
COc1ccc(-c2cc(C(F)(F)F)nn2-c2nc(C(=O)O)cs2)cc1 CHEMBL2442485 IC50 1000.0 nM
Cc1c(-c2ccccc2)nn(-c2ccc(C(=O)O)s2)c1-c1ccccc1 CHEMBL3092146 IC50 1000.0 nM
O=C(O)c1csc(-n2nc(-c3ccccc3)c3c2CCCCC3)n1 CHEMBL3127178 IC50 1000.0 nM