CCCC[C@](C)(O)C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1 CHEMBL4217198 EC50 0.068 nM
CCCCC[C@](C)(O)C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1 CHEMBL4204996 EC50 0.086 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(Cl)c(C(F)(F)F)c4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3794302 EC50 0.11 nM
C[C@@](O)(C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1)CCCCF CHEMBL4205480 EC50 0.11 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@@H]2O)ccc1Cl CHEMBL3793515 EC50 0.14 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)O)s2)cc1 CHEMBL3971632 EC50 0.15 nM
CCCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3977724 EC50 0.15 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)cc(C)c1Cl CHEMBL3794016 EC50 0.17 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4cc(Cl)c(Cl)cc4Cl)[C@H](O)C[C@@H]3O2)n1 CHEMBL3793862 EC50 0.2 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(Cl)c(Cl)c4Cl)[C@H](O)C[C@@H]3O2)n1 CHEMBL3792632 EC50 0.21 nM
C[C@@](O)(C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1)CCC(F)(F)F CHEMBL4212770 EC50 0.37 nM
CCCC[C@H](C)C[C@H](O)/C=C/[C@H]1CCC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL3754586 EC50 0.39 nM
CCCCCC(C)(O)C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1 CHEMBL4206444 EC50 0.48 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccccc4C(F)(F)F)[C@H](O)C[C@@H]3O2)n1 CHEMBL3806284 EC50 0.5 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(Cl)c(Cl)c4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3793802 EC50 0.57 nM
CCCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)O)s2)cc1 CHEMBL3947001 EC50 0.6 nM
COc1ccc(C(=O)N2CCC(COc3ccc(-c4ccc(C#N)cc4)cc3)(C(=O)O)C2)cc1 CHEMBL5285583 Ki 0.63 nM
O=C(O)c1csc(SCCN2C(=O)OC[C@@H]2/C=C/[C@@H](O)C2(CCCCF)CCC2)n1 CHEMBL3751951 EC50 0.67 nM
CCc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3794466 EC50 0.68 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3793892 EC50 0.69 nM
CCC1([C@@H](O)C/C=C/[C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]2O)CCC1 CHEMBL64246 Ki 0.74 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4cccc(C(F)(F)F)c4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3793045 EC50 0.9 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4cccc(OC(F)(F)F)c4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805981 EC50 0.9 nM
COc1c(C)cc(-c2cccc(F)c2)cc1CNc1c(C)ccc(OCC(=O)O)c1C CHEMBL3961932 EC50 0.9 nM
CCCCC(C)(C)[C@H](O)/C=C/[C@H]1CCC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL3752377 EC50 0.91 nM
Cc1ccc(OCC(=O)O)c(C)c1NCc1cc(O)cc(-c2cccc(F)c2)c1 CHEMBL3903635 EC50 1.0 nM
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O CHEMBL548 Ki 1.03 nM
O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccoc3)cc2-c2ccc(F)cc2)cc1 CHEMBL3670659 Ki 1.1 nM
C[C@@](O)(C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1)CC1CCCC1 CHEMBL4208379 EC50 1.1 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL3707245 EC50 1.1 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](CCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3806130 EC50 1.4 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3892847 EC50 1.5 nM
O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccccc3)cc2-c2ccc(F)cc2)o1 CHEMBL3670663 Ki 1.5 nM
Cc1cc2ccccc2n1CCNC(=O)c1cnc(Nc2ccccc2)nc1 CHEMBL3286711 Kb 1.6 nM
CCCCCC(=O)c1ccc(N2C(=O)CC[C@@H]2CCCc2ccc(C(=O)O)s2)cc1 CHEMBL3920756 EC50 1.6 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-c3ccccn3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4467099 EC50 1.6 nM
C=CCC1([C@@H](O)C/C=C/[C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]2O)CCC1 CHEMBL3286796 Ki 1.7 nM
COc1ccc2cc(OCC3(C(=O)O)CN(C(=O)c4ccc(F)cc4)C3)ccc2c1 CHEMBL3286797 Kb 1.8 nM
COc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3794585 EC50 1.8 nM
O=C(O)c1[nH]c(-c2cccs2)cc1-c1ccc(F)cc1 CHEMBL3670653 Ki 1.9 nM
C[C@@H]1COc2c(Cl)cc(-n3ccc4cc(F)ccc43)cc2CN1Cc1cc[nH]c(=O)c1 CHEMBL3586362 IC50 2.0 nM
CC(C)c1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3793020 EC50 2.0 nM
CCCCCC(O)c1ccc([C@H]2CCC(=O)[C@@H]2CCCc2ccc(C(=O)O)s2)cc1 CHEMBL3903611 EC50 2.0 nM
Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2F)c1C CHEMBL3919482 EC50 2.0 nM
Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2C)c1F CHEMBL3954347 EC50 2.0 nM
Cc1cc(-c2cccc(F)c2)cc(CNc2c(C)ccc(OCC(=O)O)c2C)c1C CHEMBL3917749 EC50 2.0 nM
Cc1cc(-c2ccc(F)c(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2F)c1C CHEMBL3940781 EC50 2.0 nM
C[C@](O)(C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1)CC1CCCC1 CHEMBL4213312 EC50 2.0 nM
COc1cc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC CHEMBL1368005 KB 2.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(-c2c[nH]cn2)cc1 CHEMBL4540100 KB 2.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-c3ccccc3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4471378 EC50 2.0 nM
CCCCCC(C)(O)C/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL4209929 EC50 2.1 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4ccc(C(=O)O)o4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3794226 EC50 2.2 nM
COc1cc(/C=C/C(=O)NCCc2c(C)[nH]c3ccccc23)cc(OC)c1OC CHEMBL3264207 Kb 2.4 nM
CC1(c2ccc(CN(Cc3cccc(NCC(=O)O)n3)S(=O)(=O)c3cccnc3)cc2)CC1 CHEMBL4515583 EC50 2.6 nM
CCN(CC)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286635 Kb 2.7 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2ccccn2)cc1 CHEMBL4442505 EC50 2.7 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL4466224 EC50 2.7 nM
O=C(O)COc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccnc2)c1 CHEMBL2107783 EC50 2.8 nM
O=C(O)c1[nH]c(-c2ccoc2)cc1-c1ccc(O)cc1 CHEMBL3670654 Ki 2.8 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2cccnc2)cc1 CHEMBL4591201 EC50 2.8 nM
CCCCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3753221 EC50 2.9 nM
Cc1ccc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)cc1C CHEMBL3793797 EC50 2.9 nM
COc1cc(OC)cc(-c2ccc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4449878 KB 2.9 nM
CCCCC1([C@@H](O)/C=C/[C@H]2CCC(=O)N2CCc2ccc(C(=O)O)cc2)CCC1 CHEMBL272277 EC50 3.0 nM
Cc1c(F)cc(-c2cccc(F)c2)cc1CNc1c(F)ccc(OCC(=O)O)c1F CHEMBL3932999 EC50 3.0 nM
Cc1cc(CNc2c(F)ccc(OCC(=O)O)c2C)cc(-c2cccc(F)c2)c1 CHEMBL3926711 EC50 3.0 nM
Cc1cc(CNc2c(C)ccc(OCC(=O)O)c2C)c(F)c(-c2cccc(F)c2)c1 CHEMBL3983500 EC50 3.0 nM
COc1cc(CNc2c(C)ccc(OCC(=O)O)c2C)cc(-c2cccc(F)c2)c1 CHEMBL3916293 EC50 3.0 nM
Cc1ccc(OCC(=O)O)c(C)c1NCc1cc(-c2cccc(F)c2)cc(F)c1C CHEMBL3969269 EC50 3.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)Nc2ccc(C(=O)NO)o2)cc1 CHEMBL3670662 Ki 3.1 nM
COc1cc(/C=C/C(=O)NCCc2c(C)[nH]c3c(F)cc(F)cc23)cc(OC)c1OC CHEMBL3264209 Kb 3.3 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccccc4Cl)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805767 EC50 3.3 nM
COc1cc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1 CHEMBL3264202 Kb 3.4 nM
Cc1cc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)cc(C)c1F CHEMBL3264203 Kb 3.4 nM
O=C(O)CNc1cccc(CN(Cc2cc3ccccc3s2)S(=O)(=O)c2cccnc2)n1 CHEMBL4476670 EC50 3.4 nM
Cc1cccc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)c1 CHEMBL3805554 EC50 3.6 nM
COc1cc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OCCO CHEMBL3264230 Kb 3.7 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/COc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805693 EC50 3.8 nM
COC(=O)c1ccc(CNC(=O)c2[nH]c(-c3cccs3)cc2-c2ccc(F)cc2)nc1 CHEMBL3670656 Ki 3.8 nM
O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3cccs3)cc2-c2ccc(F)cc2)nc1 CHEMBL3670658 Ki 3.8 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)ccc1C(F)(F)F CHEMBL3793809 EC50 3.9 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(Cl)cc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3793786 EC50 3.9 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/CCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805176 EC50 3.9 nM
CCCCCC(O)c1ccc([C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]2Cl)cc1 CHEMBL3936540 EC50 4.0 nM
CCCCCC(O)c1ccc([C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](C#N)C[C@H]2O)cc1 CHEMBL3973347 EC50 4.0 nM
NC(=O)c1cc(CNc2c(F)ccc(OCC(=O)O)c2F)cc(-c2cccc(F)c2)c1 CHEMBL3904996 EC50 4.0 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2ccccc2)cc1 CHEMBL4456588 EC50 4.3 nM
O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccoc3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670657 Ki 4.4 nM
CC(=O)Nc1ccc(-c2ccc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)cc1 CHEMBL4447823 KB 4.4 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL4447271 EC50 4.4 nM
CCC1(c2ccc(CN(Cc3cccc(NCC(=O)O)n3)S(=O)(=O)c3cccnc3)cc2)CC1 CHEMBL4458330 EC50 4.5 nM
CCN(CC)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1F CHEMBL3286677 Kb 4.6 nM
COc1ccc(/C=C/C(=O)NCCc2c(C)[nH]c3ccccc23)cc1OC CHEMBL3264208 Kb 4.9 nM
CC(C)(C)c1ccc(CN(Cc2cccc(OCC(=O)O)c2)S(=O)(=O)c2cccnc2)cc1 CHEMBL563646 EC50 5.0 nM
COc1c(C)cc(-c2cccc(F)c2)cc1CNc1c(F)ccc(OCC(=O)O)c1C CHEMBL3935521 EC50 5.0 nM
Cc1c(F)cc(-c2cccc(F)c2)cc1CNc1c(F)ccc(OCC(=O)O)c1C CHEMBL3939716 EC50 5.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4cccc(F)c4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3806076 EC50 5.4 nM
O=C(O)c1csc(SCCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)Cc2ccccc2)n1 CHEMBL1933725 EC50 5.6 nM
O=C(O)CNc1cccc(CN(Cc2cc3ccccc3o2)S(=O)(=O)c2cccnc2)n1 CHEMBL4470479 EC50 5.6 nM
CC(C)(CCCCF)[C@H](O)/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL3752406 EC50 5.7 nM
Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2C)c1C CHEMBL3966050 EC50 6.0 nM
Cc1cccc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)n1 CHEMBL4443217 KB 6.1 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2cccc(F)c2)cc1 CHEMBL4587628 EC50 6.1 nM
CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)O)c3C[C@H]2C[C@H]1O CHEMBL1237119 EC50 6.2 nM
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)N1C/C=C/CCCC(=O)O CHEMBL413509 Ki 6.4 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2cc(F)ccn2)nc1 CHEMBL4460924 KB 6.4 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4cccc(Cl)c4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805596 EC50 6.5 nM
CCCCC[C@@](C)(O)C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1 CHEMBL4216182 EC50 6.8 nM
CCN(CC)c1ccc(C(=O)NCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL3286702 Kb 6.9 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(F)cc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805075 EC50 7.0 nM
COC(=O)c1ccc(CNC(=O)c2[nH]c(-c3ccoc3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670655 Ki 7.0 nM
Cc1cc(CNc2c(C)ccc(OCC(=O)O)c2C)cc(-c2cccc(F)c2)c1 CHEMBL3955120 EC50 7.0 nM
CCCCC(C)(C)[C@H](O)/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1 CHEMBL3753853 EC50 7.4 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4552900 KB 7.6 nM
COc1ccccc1-c1ccc(C(=O)NCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL4446208 KB 7.7 nM
COc1cccc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)n1 CHEMBL4582943 KB 7.8 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/[C@@H](O)COc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3804978 EC50 7.9 nM
O=C(CCSCc1ccco1)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL358653 pA2 7.943 nM
O=C(O)/C=C/c1ccccc1/C=C/c1ccccc1OCc1ccccc1 CHEMBL181035 Ki 8.0 nM
C[C@@H]1COc2c(Cl)cc(-c3csc4ccccc34)cc2CN1Cc1cc[nH]c(=O)c1 CHEMBL3586361 IC50 8.0 nM
O=c1cc(CN2CCOc3c(Cl)cc(-n4ccc5cc(F)ccc54)cc3C2)cc[nH]1 CHEMBL3586360 IC50 8.0 nM
CCCCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3975238 EC50 8.0 nM
CCCCCC(=O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3921784 EC50 8.0 nM
Cc1c(OCC(=O)O)ccc(F)c1NCc1cc(O)cc(-c2cccc(F)c2)c1 CHEMBL3940318 EC50 8.0 nM
Cc1cc(-c2cc(F)cc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2F)c1C CHEMBL3958279 EC50 8.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(Br)c2)cc1 CHEMBL3906016 EC50 8.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2ccccc2F)cc1 CHEMBL3904946 EC50 8.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(F)c2F)cc1 CHEMBL3981554 EC50 8.0 nM
Cc1ccnc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4533637 KB 8.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2cccnc2)nc1 CHEMBL4469340 KB 8.3 nM
CCc1nnc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)/C=C/c3ccc(F)cc3)cc2)s1 CHEMBL1372836 KB 8.8 nM
COc1ccc2[nH]c(C)c(CCNC(=O)c3cnc(Nc4cc(C)cc(C)n4)nc3)c2c1 CHEMBL4472431 KB 8.8 nM
CCCCCC(=O)c1ccc([C@H]2[C@H](O)CC(=O)[C@@H]2C/C=C\CCCC(=O)O)cc1 CHEMBL3959653 EC50 9.0 nM
Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2F)c1O CHEMBL3928263 EC50 9.0 nM
N#Cc1c(OCC(=O)O)ccc(F)c1NCc1cc(-c2cccc(F)c2)ccc1F CHEMBL3974557 EC50 9.0 nM
COc1ccc(-c2cc(-c3ccccc3)[nH]c2C(=O)Nc2cccc(CC(=O)NO)c2)cc1 CHEMBL3670664 Ki 9.2 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCCCC2)cc1 CHEMBL3286683 Kb 9.4 nM
O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccc(O)cc3)cc2-c2ccoc2)cc1 CHEMBL3670661 Ki 9.4 nM
COc1cccc(-c2ccc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4483355 KB 9.5 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCOCC2)cc1 CHEMBL3286688 Kb 9.6 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N(C)C)cc1 CHEMBL3286634 Kb 9.8 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](CCCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805044 EC50 10.0 nM
Cc1c(OCC(=O)O)ccc(F)c1NCc1cc(-c2cccc(F)c2)ccc1F CHEMBL3916133 EC50 10.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(F)c2)cc1 CHEMBL3974652 EC50 10.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cc(F)ccc2F)cc1 CHEMBL3900245 EC50 10.0 nM
COc1ccccc1-c1ccc(C(=O)NCCc2c(C)[nH]c3ccccc23)cn1 CHEMBL4539848 KB 10.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2ccccn2)nc1 CHEMBL4448498 KB 10.7 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N(C)C)cc1 CHEMBL3286701 Kb 10.8 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@@H]2F)ccc1Cl CHEMBL3793167 EC50 11.0 nM
CC(Nc1c(F)ccc(OCC(=O)O)c1F)c1cc(-c2cccc(F)c2)ccc1F CHEMBL3986985 EC50 11.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2ccc(F)cc2)cc1 CHEMBL3892492 EC50 11.0 nM
Cc1cc(/C=C/C(=O)NCCc2c(C)[nH]c3ccccc23)cc(C)c1F CHEMBL3264210 Kb 11.3 nM
Cc1cc2ccccc2n1CCNC(=O)/C=C/c1ccc(OCCO)c(OCCO)c1 CHEMBL3264225 Kb 11.4 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(-c2ccccc2O)nc1 CHEMBL4454345 KB 11.5 nM
Cc1cc2ccccc2n1CCNC(=O)/C=C/c1ccc(OCCCO)cc1 CHEMBL3264229 Kb 11.8 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4458392 KB 11.8 nM
CCCN(CCC)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286636 Kb 11.9 nM
CC(=O)Nc1ccc(-c2ccc(C(=O)NCCc3c(C)[nH]c4ccccc34)nc2)cc1 CHEMBL4469339 KB 12.8 nM
COc1ccccc1/C=C/C(=O)NCCn1c(C)cc2ccccc21 CHEMBL3264243 Kb 13.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3793209 EC50 13.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(C(F)(F)F)cc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805408 EC50 13.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](/C=C/CCCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805169 EC50 13.0 nM
O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3cccs3)cc2-c2ccc(O)cc2)cc1 CHEMBL3670660 Ki 13.0 nM
Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2F)c1F CHEMBL3971868 EC50 13.0 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccc(F)cc34)cn2)c1 CHEMBL4537092 KB 13.0 nM
CCC1(c2ccc(CN(Cc3cccc(NCC(=O)O)n3)S(=O)(=O)c3cccnc3)cc2)CCC1 CHEMBL4594090 EC50 13.0 nM
CC(C)C[C@H]1CN(CC(=O)NCCC(=O)N[C@@H](CCCCNC(=S)Nc2ccccc2)C(N)=O)C(=O)CCSCc2ccc(cc2)C(=O)N[C@@H](CC(C)C)CN(C(=O)CC2CC2)CC(=O)N[C@@H](CCCCN)CN(C(=O)CCc2ccccc2)CC(=O)N[C@@H](Cc2ccccc2)CN(C(=O)CCC2CCCCC2)CC(=O)N1 CHEMBL5281349 Kd 13.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(-c2c[nH]cn2)cc1 CHEMBL5269542 Kb 13.2 nM
COc1ccc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)/C=C/c3ccc(C)cc3)cc2)nn1 CHEMBL1573791 KB 13.3 nM
Cc1cc2ccccc2n1CCNC(=O)/C=C/c1ccc(OCCO)cc1 CHEMBL3264228 Kb 13.6 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccc(OC(F)(F)F)cc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805122 EC50 14.0 nM
O=C(O)COc1ccc(F)c(NCc2cc(-c3ccc(F)c(F)c3)ccc2F)c1F CHEMBL3944601 EC50 14.0 nM
Cc1cc2cc(F)ccc2n1CCNC(=O)c1ccc(N2CCOCC2)cc1 CHEMBL3286693 Kb 14.9 nM
CCCCC[C@H](O)/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL222715 EC50 15.0 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)co4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3793009 EC50 15.0 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2C=CCc2ccc(C(=O)O)s2)cc1 CHEMBL3962183 EC50 15.0 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2/C=C/Cc2ccc(C(=O)O)s2)cc1 CHEMBL3959769 EC50 15.0 nM
Cc1cc(-c2ccccc2)cc(CNc2c(F)ccc(OCC(=O)O)c2F)c1C CHEMBL3898152 EC50 15.0 nM
CC(C)(C)c1ccc(CN(Cc2cccc3oc(C(=O)O)cc23)S(=O)(=O)c2cccnc2)cc1 CHEMBL4443289 Ki 15.0 nM
CCNc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286633 Kb 15.5 nM
CCCC[C@H](O)/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL251294 EC50 16.0 nM
C[C@H](NC(=O)c1cscc1Cc1cccc(Cl)c1)c1ccc(C(=O)O)cc1 CHEMBL599051 Ki 16.0 nM
CC(C)(C)c1ccc(CN(Cc2cccc(OCC(=O)[O-])c2)S(=O)(=O)c2cccnc2)cc1 CHEMBL2105672 Ki 16.0 nM
CC(C)C[C@H]1CN(CC(=O)NCCC(=O)N[C@@H](CCCCNC(=S)Nc2ccc(-c3c4ccc(=O)cc-4oc4cc(O)ccc34)c(C(=O)O)c2)C(N)=O)C(=O)CCSCc2ccc(cc2)C(=O)N[C@@H](CCCCN)CN(C(=O)CCc2ccccc2)CC(=O)N[C@@H](CC(C)C)CN(C(=O)CCC2CCCCC2)CC(=O)N[C@@H](Cc2ccccc2)CN(C(=O)Cc2ccc3ccccc3c2)CC(=O)N1 CHEMBL5279002 Kd 16.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(-c2nnn[nH]2)cc1 CHEMBL3286660 Kb 16.4 nM
COc1ccc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3264241 Kb 16.5 nM
CCCCC[C@@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O CHEMBL62570 EC50 16.5 nM
CCc1nnc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)/C=C/c3ccccc3)cc2)s1 CHEMBL1361498 KB 16.7 nM
O=C(O)COc1ccc(F)c(NCc2cc(O)cc(-c3cccc(F)c3)c2)c1F CHEMBL3929662 EC50 17.0 nM
O=C(O)COc1ccc(F)c(NCc2c(F)ccc(-c3cccc(F)c3)c2F)c1F CHEMBL3892751 EC50 17.0 nM
COc1c(C)cc(-c2cccc(F)c2)cc1CNc1c(F)ccc(OCC(=O)O)c1F CHEMBL3893770 EC50 17.0 nM
COc1cc(/C=C/C(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc(OC)c1OC CHEMBL3264204 Kb 17.8 nM
O=C(O)/C=C/c1ccccc1/C=C/Cc1cccc(OCc2ccccc2)c1 CHEMBL1237298 Ki 18.0 nM
COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)/C=C/c3ccc(F)cc3)cc2)ncn1 CHEMBL1410750 KB 18.0 nM
COCCCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3753788 EC50 18.0 nM
COc1cc(CNc2c(F)ccc(OCC(=O)O)c2F)cc(-c2cccc(F)c2)c1 CHEMBL3901709 EC50 18.0 nM
Cc1cc(OCC(=O)O)c(C)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F CHEMBL3965998 EC50 18.0 nM
C[C@@H](Nc1c(F)ccc(OCC(=O)O)c1F)c1cc(-c2cccc(F)c2)ccc1F CHEMBL3899837 EC50 18.0 nM
CC(C)C1(c2ccc(CN(Cc3cccc(NCC(=O)O)n3)S(=O)(=O)c3cccnc3)cc2)CC1 CHEMBL4462507 EC50 18.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N(C)C)c(F)c1 CHEMBL3286674 Kb 18.1 nM
CCCCC(C)(C)[C@H](O)/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL257658 EC50 19.0 nM
COc1ccc(S(=O)(=O)N(Cc2ccc(C(C)(C)C)cc2)Cc2cccc(NCC(=O)O)n2)cc1 CHEMBL4548451 EC50 19.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N2CCCCC2)cc1 CHEMBL3286703 Kb 19.8 nM
O=c1cc(CN2CCOc3c(Cl)cc(-c4csc5ccccc45)cc3C2)cc[nH]1 CHEMBL3586359 IC50 20.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cncnc1)C2 CHEMBL3586312 IC50 20.0 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4c(F)cc(F)cc34)cn2)c1 CHEMBL4541923 KB 20.0 nM
CCNc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1C(F)(F)F CHEMBL3286679 Kb 20.2 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc2c(c1)n(C)c(=O)n2C CHEMBL3286661 Kb 20.9 nM
CC#CCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3753268 EC50 21.0 nM
COc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1OC CHEMBL3286631 Kb 22.3 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCCCCC2)cc1 CHEMBL3286687 Kb 22.6 nM
CCCC/C=C(C)/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL398948 EC50 23.0 nM
CO[C@H]1C[C@@H]2O[C@@H](c3nc(C(=O)O)cs3)CC[C@@H]2[C@H]1COc1ccc(Cl)c(C)c1 CHEMBL3793724 EC50 23.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](COc4ccccc4F)[C@H](O)C[C@@H]3O2)n1 CHEMBL3806060 EC50 23.0 nM
CCc1nnc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(OC)cc3)cc2)s1 CHEMBL1503476 KB 23.1 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(-c2ccccc2)nc1 CHEMBL4442361 KB 23.2 nM
O=C(O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2Cl)c1F CHEMBL3963438 EC50 24.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCCC2)cc1 CHEMBL3286682 Kb 24.7 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4c(Cl)cc(Cl)cc34)cn2)c1 CHEMBL4588859 KB 25.1 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCOCC2)c(F)c1 CHEMBL3286654 Kb 25.7 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)o2)cc1 CHEMBL3928130 EC50 26.0 nM
Cc1ccc(OCC(=O)O)c(C)c1NCc1cc(-c2cccc(F)c2)ccc1F CHEMBL3964577 EC50 26.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCC(O)CC2)cc1 CHEMBL3286657 Kb 26.8 nM
Cc1ccc(OC[C@@H]2[C@H]3CC[C@H](c4nc(C(=O)O)cs4)O[C@H]3C[C@H]2O)cc1 CHEMBL3805316 EC50 27.0 nM
CCCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3907809 EC50 27.0 nM
CC(C)(C)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3908484 Ki 27.0 nM
N#Cc1cc(CNc2c(F)ccc(OCC(=O)O)c2F)cc(-c2cccc(F)c2)c1 CHEMBL3910551 EC50 27.0 nM
O=C(O)c1csc([C@H]2CC[C@@H]3[C@@H](CCCCCOc4ccccc4)[C@H](O)C[C@@H]3O2)n1 CHEMBL3805455 EC50 28.0 nM
CC(C)(C)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)o2)cc1 CHEMBL3891401 EC50 28.0 nM
O=C(O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F CHEMBL3931335 EC50 28.0 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccc(Cl)cc34)cn2)c1 CHEMBL4587876 KB 28.3 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N2CCOCC2)cc1 CHEMBL3286704 Kb 28.6 nM
CCOCCC1([C@H](O)/C=C/[C@H]2COC(=O)N2CCSc2nc(C(=O)O)cs2)CCC1 CHEMBL3753898 EC50 29.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(C3CCCCC3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4466523 EC50 29.0 nM
COc1cccc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)c1 CHEMBL3264242 Kb 29.2 nM
COc1ccccc1-c1ncc(C(=O)NCCc2c(C)[nH]c3ccccc23)cn1 CHEMBL4446855 KB 29.6 nM
COc1cc(N2CCc3cc(Cl)ccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586347 IC50 30.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2ccc(F)c(F)c2)cc1 CHEMBL3976710 EC50 30.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCC(C)CC2)cc1 CHEMBL3286684 Kb 30.3 nM
CC(C)(C)CC[C@](C)(O)C/C=C/[C@H]1CCC(=O)[C@@H]1CCSc1nc(C(=O)O)cs1 CHEMBL4211120 EC50 31.0 nM
CCCC1([C@@H](O)C/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2CCCCCCC(=O)O)CCC1 CHEMBL1628262 EC50 32.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(-n2nn[nH]c2=S)cc1 CHEMBL3286659 Kb 32.2 nM
CC(=O)c1cccc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)n1 CHEMBL4466583 KB 32.5 nM
CCCC1([C@H](O)C/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2CCCCCCC(=O)OC)CCC1 CHEMBL271896 EC50 33.0 nM
CCc1nnc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)/C=C/c3cccs3)cc2)s1 CHEMBL1412254 KB 33.1 nM
COc1cc(OC)cc(-c2ccc(C(=O)NCCc3c(C)[nH]c4ccccc34)nc2)c1 CHEMBL4567172 KB 33.6 nM
O=C(O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1Cl CHEMBL3929987 EC50 34.0 nM
CCc1nnc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)/C=C/c3ccc(OC)cc3)cc2)s1 CHEMBL1507392 KB 34.5 nM
CCCCC[C@H](O)CC[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL376347 Ki 35.0 nM
CCCC/C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL251505 EC50 35.0 nM
Cc1cc(CNc2c(F)ccc(OCC(=O)O)c2F)cc(-c2cccc(F)c2)c1 CHEMBL3892911 EC50 35.0 nM
Cc1cc(CNc2c(F)ccc(OCC(=O)O)c2C)c(F)c(-c2cccc(F)c2)c1 CHEMBL3912323 EC50 35.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(C(F)(F)F)c2)cc1 CHEMBL3978590 EC50 35.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-c3ccc(F)cc3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4449902 EC50 35.0 nM
O=C(O)c1ccc(CCCN2[C@@H](/C=C/C(O)Cc3cccc(OC(F)(F)F)c3)CCS2(=O)=O)s1 CHEMBL3965497 EC50 38.0 nM
CCC(C)(O)c1cccc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)n1 CHEMBL4593054 KB 39.0 nM
COc1cc(-n2ccc3cc(F)ccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586346 IC50 40.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)/C=C/c1ccc(OCCO)c(OCCO)c1 CHEMBL3264227 Kb 41.1 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(-n2cnnn2)cc1 CHEMBL3286658 Kb 42.2 nM
O=C(O)c1ccc(CNC(=O)c2c(Cl)sc(Cl)c2Cc2cccc(Cl)c2)cc1 CHEMBL601299 Ki 43.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-n3cncn3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4449855 EC50 43.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2cc(C(C)(C)C)ccn2)nc1 CHEMBL4475650 KB 44.5 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCN(C)CC2)c(F)c1 CHEMBL3286655 Kb 45.0 nM
O=C(O)COc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1Cl CHEMBL3917219 EC50 45.0 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2ccccc2F)cc1 CHEMBL4561017 EC50 45.0 nM
CC(C)OC(=O)COc1cccc(CN(Cc2ccc(-n3cccn3)cc2)S(=O)(=O)c2cccnc2)c1 CHEMBL2105692 EC50 46.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(-c2ccccc2F)nc1 CHEMBL4447998 KB 48.4 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(-c2nnn[nH]2)cc1 CHEMBL4461104 KB 48.5 nM
COc1cccc(-c2ccc(C(=O)NCCc3c(C)[nH]c4ccccc34)nc2)c1 CHEMBL4451448 KB 48.6 nM
Cc1cc(OCC(=O)O)c(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F CHEMBL3939740 EC50 50.0 nM
CC(=O)N1CCN(c2ccc(C(=O)NCCn3c(C)cc4ccccc43)cc2)CC1 CHEMBL3286664 Kb 50.2 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(NC(=O)c2ccccc2F)cc1 CHEMBL3286644 Kb 51.0 nM
O=C(O)COc1ccc(F)c(NCc2cc(F)cc(-c3cccc(F)c3)c2)c1F CHEMBL3919144 EC50 52.0 nM
CCCCCC[C@H](O)/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL257217 Ki 54.0 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4coc(C(=O)O)c4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3792668 EC50 55.0 nM
Cc1cc(CNc2c(F)ccc(OCC(=O)O)c2F)c(F)c(-c2cccc(F)c2)c1 CHEMBL3934986 EC50 55.0 nM
CCNc1ncc(C(=O)NCCn2c(C)cc3ccccc32)cn1 CHEMBL3286689 Kb 57.8 nM
CCCCCC(O)c1ccc([C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@@H]2Cl)cc1 CHEMBL3959926 EC50 58.0 nM
COc1cc(/C=C/C(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc(OC)c1OCCO CHEMBL3264231 Kb 58.3 nM
CCCCC[C@@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O CHEMBL64804 EC50 59.0 nM
C/C(=C/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1)CC1CCCC1 CHEMBL248678 Ki 60.0 nM
COc1cc(-n2cc(Cl)c3ccccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586340 IC50 60.0 nM
O=C(O)c1csc(SCCN2C(=O)OC[C@@H]2/C=C/[C@@H](O)C2(CCC3CCCCC3)CCC2)n1 CHEMBL3754197 EC50 60.0 nM
CCN(CC)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1OC CHEMBL3286680 Kb 61.2 nM
Cc1cc2cc(F)ccc2n1CCNC(=O)c1ccc(N2CCN(C)CC2)c(F)c1 CHEMBL3286694 Kb 62.2 nM
CCN(CC)c1ccc(C(=O)NCCn2ccc3ccccc32)cc1 CHEMBL3286641 Kb 62.9 nM
c1ccc(CCSCc2ccc(-c3ccccc3CCc3nnn[nH]3)cc2)cc1 CHEMBL2112332 Ki 63.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCN(C)CC2)cc1 CHEMBL3286651 Kb 64.0 nM
C[C@@H](CCCc1ccccc1)[C@@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3937596 EC50 65.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N2CCOCC2)c(F)c1 CHEMBL3286705 Kb 66.0 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C(F)(F)F)[nH]c4ccccc34)cn2)c1 CHEMBL4476203 KB 66.0 nM
CCCCN(CCC)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286637 Kb 68.8 nM
Cc1ccc(-c2cccc(F)c2)cc1CNc1c(F)ccc(OCC(=O)O)c1F CHEMBL3945923 EC50 69.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586309 IC50 70.0 nM
O=C(O)COc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F CHEMBL3961188 EC50 73.0 nM
Cc1cc2ccccc2n1CCNC(=O)/C=C/c1ccc(OCCCN(C)C)cc1 CHEMBL3264236 Kb 74.6 nM
O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)CCC2CCC2)cc1 CHEMBL222782 Ki 75.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-c3ccc(Cl)cc3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4531171 EC50 75.0 nM
COc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286632 Kb 75.6 nM
Cc1cc2ccccc2n1CCNC(=O)c1cnc(N2CCOCC2)nc1 CHEMBL3286690 Kb 76.5 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2cccc(C(C)(C)C)n2)nc1 CHEMBL4578580 KB 79.3 nM
Clc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586353 IC50 80.0 nM
COc1cc(-n2ccc3cc(Cl)ccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586342 IC50 80.0 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCCC(=O)O)n2)S(=O)(=O)c2cccnc2)cc1 CHEMBL4451941 EC50 83.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(CNC(=O)OC(C)(C)C)cc1 CHEMBL3286671 Kb 84.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc2[nH]c(=S)[nH]c(=O)c2c1 CHEMBL3286666 Kb 84.1 nM
COc1cc(/C=C/C(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OCCN(C)C CHEMBL3264235 Kb 84.5 nM
COc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1F CHEMBL3286676 Kb 86.8 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc2[nH]nnc2c1 CHEMBL3286665 Kb 87.5 nM
CCCC/C=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL251709 Ki 88.0 nM
Cc1ccc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c(C)n1 CHEMBL4559934 KB 88.1 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCC(C(=O)O)CC2)cc1 CHEMBL3286686 Kb 89.7 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(C)(=O)=O)cc1 CHEMBL4554216 EC50 91.0 nM
CC(O)(C/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1)CC1CCCCC1 CHEMBL4214346 EC50 92.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C2CCCN(C(=O)OC(C)(C)C)C2)cc1 CHEMBL3286667 Kb 95.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2cccc(F)n2)nc1 CHEMBL4473549 KB 96.0 nM
CC(=O)Nc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286643 Kb 97.0 nM
Cc1ccc(OCC(=O)O)c(F)c1NCc1cc(-c2cccc(F)c2)ccc1F CHEMBL3943109 EC50 99.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C(=O)OC(C)(C)C)cc1 CHEMBL3286649 Kb 100.0 nM
COc1cc(-n2ccc3cc(C#N)ccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586345 IC50 100.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccc(C#N)c1)C2 CHEMBL3586324 IC50 100.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1ccc(S(C)(=O)=O)cc1)C2 CHEMBL3586322 IC50 100.0 nM
COc1ccc(CN2CCOc3c(cc(-c4csc5ccccc45)cc3OC)C2)cn1 CHEMBL3586314 IC50 100.0 nM
CC(C)(C)c1ccc([C@H]2[C@H](O)CC(=O)[C@@H]2CCCCCCC(=O)O)cc1 CHEMBL3930718 EC50 102.0 nM
CC(=O)c1ccnc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4474817 KB 104.0 nM
COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3sc4cc(F)ccc4c3Cl)cc2)nc(OC)n1 CHEMBL1550812 KB 108.0 nM
CC(C)(C)c1cccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2cccnc2)c1 CHEMBL4566584 EC50 109.0 nM
O=C(O)/C=C/c1ccccc1/C=C/Cc1ccccc1Oc1ccccc1 CHEMBL1237304 Ki 110.0 nM
O=C(O)COc1cccc(NCc2cc(-c3cccc(F)c3)ccc2F)c1 CHEMBL3958411 EC50 110.0 nM
Cc1cc(OC[C@@H]2[C@H]3CC[C@H](c4csc(C(=O)O)c4)O[C@H]3C[C@H]2O)ccc1Cl CHEMBL3794185 EC50 114.0 nM
CC(C)(C)c1ccc([C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]2O)cc1 CHEMBL3899346 EC50 118.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N2CCOCC2)nc1 CHEMBL4451668 KB 118.0 nM
O=C(O)CNc1cccc(CN(CCCCCc2ccccc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4539881 EC50 118.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(C(F)(F)F)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4451786 EC50 119.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C2CCCCC2)cc1 CHEMBL3286662 Kb 120.0 nM
O=C(NCCn1c(C(F)(F)F)cc2ccccc21)c1ccc(N2CCOCC2)cc1 CHEMBL3286696 Kb 120.0 nM
O=C(O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(O)Cc2cccc(Cl)c2)cc1 CHEMBL3902700 EC50 123.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1nc2cc(F)ccc2[nH]1 CHEMBL3286714 Kb 130.0 nM
Cc1c(-c2cccc(F)c2)ccc(F)c1CNc1c(F)ccc(OCC(=O)O)c1F CHEMBL3941975 EC50 130.0 nM
COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3cccs3)cc2)nc(OC)n1 CHEMBL1374570 KB 132.0 nM
CCCC/C(C)=C/C=C/[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL251504 Ki 134.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N2CCN(C)CC2)cc1 CHEMBL3286706 Kb 135.0 nM
CS(=O)(=O)c1cc(F)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3 CHEMBL426559 Ki 136.0 nM
Cc1cc2ccccc2n1CCNC(=O)/C=C/c1ccc(OCCN(C)C)cc1 CHEMBL3264237 Kb 137.0 nM
CC(=O)Nc1ccc(C(=O)NCCc2c(C)[nH]c3ccccc23)cc1 CHEMBL3286699 Kb 138.0 nM
O=C(O)CCc1ccccc1-c1ccc(CSCCc2ccccc2)cc1 CHEMBL86799 Ki 140.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C#N)cc1 CHEMBL3286648 Kb 140.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C#N)c(F)c1 CHEMBL3286400 Kb 140.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCCN(C)CC2)cc1 CHEMBL3286656 Kb 148.0 nM
O=C(O)c1ccc(COC[C@H]2CCC(=O)N2c2ccc(C(O)Cc3ccccc3)cc2)o1 CHEMBL3906402 EC50 148.0 nM
C[C@@H](CCCc1ccccc1)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3975743 EC50 148.0 nM
O=C(O)c1ccc(CCCc2ccccc2OCc2ccccc2)cc1 CHEMBL124199 Ki 150.0 nM
CC(=O)Oc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286642 Kb 150.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C(N)=O)cc1 CHEMBL3286645 Kb 150.0 nM
CCN(CC)c1ccc(C(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc1 CHEMBL3286695 Kb 150.0 nM
CCNc1ncc(C(=O)NCCC2C(C)=Nc3ccccc32)cn1 CHEMBL3286712 Kb 155.0 nM
C[C@@H](CCCCc1ccccc1)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3945327 EC50 157.0 nM
O=C(O)c1csc(SCCN2C(=O)OC[C@@H]2/C=C/[C@@H](O)C2(CCc3ccccc3)CCC2)n1 CHEMBL3753622 EC50 160.0 nM
O=C(O)COc1ccc(F)c(NCc2cccc(-c3cccc(F)c3)c2)c1F CHEMBL3936868 EC50 160.0 nM
O=C(O)COc1ccc(F)c(NCc2cc(O)cc(-c3cccc(F)c3)c2F)c1F CHEMBL3971730 EC50 160.0 nM
CC(=O)c1ccc(Nc2ncc(C(=O)NCCc3c(C)[nH]c4ccccc34)cn2)nc1 CHEMBL4469846 KB 166.0 nM
CC/C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL251710 Ki 173.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1cnc2ccc(F)cc2c1O CHEMBL3286715 Kb 175.0 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCC(O)c3c(C)[nH]c4ccccc34)cn2)c1 CHEMBL4476144 KB 183.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N2CCCCC2)nc1 CHEMBL4474035 KB 185.0 nM
CCN(CC)c1ccc(C(=O)NCCn2c(C)nc3ccccc32)cc1 CHEMBL3286697 Kb 190.0 nM
Cc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586352 IC50 200.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1ccc(=O)[nH]c1)C2 CHEMBL3586315 IC50 200.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1OC)C2 CHEMBL3586313 IC50 200.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1ccncc1)C2 CHEMBL3586311 IC50 200.0 nM
Cc1sc(C)c(C(=O)N[C@@H](C)c2ccc(C(=O)O)cc2)c1Cc1ccc(Cl)cc1 CHEMBL599262 Ki 202.0 nM
CCCCC[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCCCCC(=O)O CHEMBL3955128 EC50 205.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N)cc1 CHEMBL3286638 Kb 210.0 nM
COc1cc(CCC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC CHEMBL3264220 Kb 214.0 nM
O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2CC[C@@H](O)CCC2CCC2)cc1 CHEMBL223744 Ki 220.0 nM
CC(=O)c1cc(S(C)(=O)=O)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3 CHEMBL383484 Ki 230.0 nM
Cc1[nH]c2ccccc2c1CCNC(=O)c1cnc(Nc2cccc(C#N)n2)nc1 CHEMBL4457181 KB 230.0 nM
Cc1cc2ccccc2n1CCNC(=O)C1CC1c1ccc(F)cc1 CHEMBL3264233 Kb 236.0 nM
O=C(O)c1ccc(CNC(=O)c2cc(F)ccc2Oc2ccc(F)cc2)cc1 CHEMBL4092846 IC50 236.0 nM
CCCCCC(O)c1ccc([C@H]2CCC(=O)[C@@H]2CCCCCCC(=O)O)cc1 CHEMBL1722929 Ki 240.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C(=O)O)cc1 CHEMBL3286650 Kb 245.0 nM
O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)Cc2cccc(Cl)c2)cc1 CHEMBL258332 EC50 250.0 nM
COc1ccccc1-c1ccc(C(=O)NCCc2c(C)[nH]c3ccccc23)cc1F CHEMBL4521211 KB 250.0 nM
O=C(CCS(=O)(=O)Cc1ccco1)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL148449 pA2 251.19 nM
Cc1cc(C)nc(Nc2ncc(C(=O)NCCc3c(C)nn4ccccc34)cn2)c1 CHEMBL4470891 KB 254.0 nM
O=C(/C=C/c1ccc(OCCO)c(OCCO)c1)NCCn1c(C(F)(F)F)cc2ccccc21 CHEMBL3264226 Kb 260.0 nM
CC(C)[C@@H](OCCOc1ccccc1)C(=O)N[C@@H](C)c1ccc(C(=O)O)cc1 CHEMBL3667607 Ki 261.0 nM
CC(C)(C)c1ccc([C@@H]2[C@@H](CCCCCCC(=O)O)[C@H](Cl)C[C@H]2O)cc1 CHEMBL3958410 EC50 264.0 nM
CCCC1(C(O)c2cccc([C@@H]3[C@@H](Cc4cccc(OCC(=O)O)c4)[C@H](Cl)C[C@H]3O)c2)CCC1 CHEMBL3986829 EC50 266.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(C#N)cc1F CHEMBL3286681 Kb 280.0 nM
CC1=Nc2ccccc2C1CCNC(=O)c1cnc(N2CCOCC2)nc1 CHEMBL3286713 Kb 280.0 nM
CN(CC(=O)O)c1cccc(CN(Cc2ccc(C(C)(C)C)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4519118 EC50 283.0 nM
COc1cccc(OC)c1C1(C(=O)NS(=O)(=O)Cc2ccc(N3Cc4c(c(OCC(F)(F)F)c5cccnc5c4OCC(F)(F)F)C3=O)c(C)c2)CC1 CHEMBL404199 Ki 300.0 nM
COc1cc(-n2ccc3ccccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586337 IC50 300.0 nM
COc1cc(-c2cccc3ccccc23)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586328 IC50 300.0 nM
COc1ccc(/C=C/C(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc1 CHEMBL3264205 Kb 305.0 nM
Cc1cc(/C=C/C(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc(C)c1F CHEMBL3264206 Kb 306.0 nM
O=C(O)CNc1cccc(CN(Cc2ccc(-c3ccnnc3)cc2)S(=O)(=O)c2cccnc2)n1 CHEMBL4473407 EC50 307.0 nM
CC(=O)c1cc(F)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3 CHEMBL385126 Ki 310.0 nM
CCN(CC)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1C(F)(F)F CHEMBL3286678 Kb 310.0 nM
CCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2ccc(C(=O)O)s2)cc1 CHEMBL3918349 EC50 312.0 nM
CCCC1(C(O)c2cccc([C@@H]3[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]3O)c2)CCC1 CHEMBL3982222 EC50 322.0 nM
CCCCC[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3916499 EC50 326.0 nM
COc1cc(/C=C/C(=O)NCCc2c(C)oc3ccccc23)cc(OC)c1OC CHEMBL3264211 Kb 333.0 nM
COc1cc(/C=C/C(=O)OCCn2c(C)cc3ccccc32)cc(OC)c1OC CHEMBL3264232 Kb 340.0 nM
CCCCC(O)Cc1ccc([C@H]2CCC(=O)[C@@H]2CCCCCCC(=O)O)cc1 CHEMBL3964261 EC50 343.0 nM
CC(C)(C)c1ccc(CN(Cc2csc(NCC(=O)O)n2)S(=O)(=O)c2cccnc2)cc1 CHEMBL4521659 EC50 360.0 nM
Cc1cccc(CCCc2ccccc2/C=C/C(=O)O)c1OCc1ccccc1 CHEMBL424975 Ki 380.0 nM
Cc1cc2ccccc2n1CCNC(=O)C1CCC(c2ncccn2)CC1 CHEMBL3286692 Kb 380.0 nM
C[C@@H](NC(=O)c1c(Cl)sc(Cl)c1Cc1cccc(Cl)c1)c1ccc(C(=O)O)cc1 CHEMBL591431 Ki 384.0 nM
CC(O)c1cc(S(C)(=O)=O)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3 CHEMBL207203 Ki 390.0 nM
O=C(O)CCC/C=C\C[C@@H]1[C@@H](c2ccc(C(O)C3CCCCC3)cc2)[C@H](O)C[C@H]1Cl CHEMBL3906280 EC50 392.0 nM
CCCC1(C(O)CCCN2CCC(=O)N2CCc2ccc(C(=O)O)cc2)CCC1 CHEMBL250153 EC50 393.0 nM
COc1cc(-n2ccc3c(Cl)cccc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586341 IC50 400.0 nM
COc1cc(-c2nsc3ccccc23)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586335 IC50 400.0 nM
O=C(O)CCC/C=C\C[C@H]1C(=O)C[C@@H](O)[C@@H]1c1ccc2c(c1)CCC2O CHEMBL3956391 EC50 405.0 nM
O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 CHEMBL426387 Ki 410.0 nM
COc1cc(C(N)CC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC CHEMBL3264221 Kb 410.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCNCC2)cc1 CHEMBL3286663 Kb 410.0 nM
CC(C)(C)c1ccc(CN(Cc2ccc3cc(C(=O)O)oc3c2)S(=O)(=O)c2cccnc2)cc1 CHEMBL4448995 Ki 433.0 nM
O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)Cc2ccccc2)cc1 CHEMBL272276 EC50 434.0 nM
O=C(O)CCCCCC[C@H]1C(=O)C[C@@H](O)[C@@H]1c1ccc(C(O)C2CCCCC2)cc1 CHEMBL3949225 EC50 450.0 nM
Cc1sc(C)c(C(=O)N[C@@H](C)c2ccc(C(=O)O)cc2)c1Cc1cccc(Cl)c1 CHEMBL604546 Ki 467.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(S(N)(=O)=O)cc1 CHEMBL3286669 Kb 486.0 nM
CC(C)C(O)c1ccc([C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]2O)cc1 CHEMBL3901088 EC50 497.0 nM
CCOC(=O)C1CCN(c2ccc(C(=O)NCCn3c(C)cc4ccccc43)cc2)CC1 CHEMBL3286685 Kb 500.0 nM
O=C(O)CCC/C=C\C[C@@H]1[C@@H](c2ccc(C3(O)CCC3)cc2)[C@H](O)C[C@H]1Cl CHEMBL3915426 EC50 513.0 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2COCc2cccc(C(=O)O)c2)cc1 CHEMBL3924987 EC50 517.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1cccnc1N CHEMBL3286691 Kb 520.0 nM
CC(C)(CO)c1ccc([C@H]2[C@H](O)CC(=O)[C@@H]2CCCCCCC(=O)O)cc1 CHEMBL3919393 EC50 526.0 nM
O=C(O)CCCCCC[C@@H]1[C@@H](c2ccc3c(c2)CCC3O)[C@H](O)C[C@H]1Cl CHEMBL3909111 EC50 529.0 nM
CC(=O)Nc1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1F CHEMBL3286675 Kb 530.0 nM
CCCC1(C(O)c2cccc([C@@H]3[C@@H](CCCCCCC(=O)O)[C@H](Cl)C[C@H]3O)c2)CCC1 CHEMBL3922332 EC50 546.0 nM
CC(C)(C)c1ccc(N2C(=O)CC[C@@H]2CCCCCCC(=O)O)cc1 CHEMBL3929446 EC50 548.0 nM
Cc1cccc(/C=C/Cc2ccccc2/C=C/C(=O)O)c1OCc1ccccc1 CHEMBL1237295 Ki 550.0 nM
CC(CCN1CCC(=O)N1CCc1ccc(C(=O)O)cc1)Cc1cccc(CCc2ccccc2)c1 CHEMBL400447 Ki 560.0 nM
O=C(O)COC[C@H]1CC[C@H](COC(=O)N(c2ccccc2)c2cccc(F)c2)CC1 CHEMBL3933704 Ki 570.0 nM
O=C(Cc1ccccc1-c1ccc(CSCCc2ccccc2)cc1)NS(=O)(=O)c1cccs1 CHEMBL86886 Ki 590.0 nM
CCCCCC(O)CCN1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL249136 EC50 595.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1ccc(C#N)cc1)C2 CHEMBL3586321 IC50 600.0 nM
COC(=O)c1ccc(CN2CCOc3c(cc(-c4csc5ccccc45)cc3OC)C2)cc1 CHEMBL3586320 IC50 600.0 nM
CCCCCC(O)c1ccc([C@H]2CC[C@@H](Cl)[C@@H]2CCCCCCC(=O)O)s1 CHEMBL3950412 Ki 600.0 nM
CCCCCC(O)c1ccc([C@H]2CC[C@@H](F)[C@@H]2CCCCCCC(=O)O)cc1 CHEMBL3896693 Ki 600.0 nM
O=C(O)COC[C@H]1CC[C@H](COC(=O)N(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL3301604 Ki 610.0 nM
COCc1cccc(C[C@H](O)/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(=O)O)c1 CHEMBL292964 EC50 610.0 nM
CC(C)(C)c1ccc(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2cccc(Cl)c2)cc1 CHEMBL4460294 EC50 620.0 nM
Cc1cccc(/C=C/Cc2cccc(/C=C/C(=O)O)c2)c1OCc1ccccc1 CHEMBL1237299 Ki 630.0 nM
O=C(CC[S+]([O-])Cc1ccco1)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL359231 pA2 630.96 nM
O=C(CCCCCl)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21 CHEMBL114395 pA2 630.96 nM
CCCC1(C(O)c2cccc([C@H]3[C@H](O)CC(=O)[C@@H]3CCCCCCC(=O)O)c2)CCC1 CHEMBL3972401 EC50 635.0 nM
CC(C)(C)C1CCC(CN(Cc2cccc(NCC(=O)O)n2)S(=O)(=O)c2cccnc2)CC1 CHEMBL4514124 EC50 649.0 nM
COc1ccc(CCCNC(=O)/C=C/c2cc(OC)c(OC)c(OC)c2)cc1 CHEMBL3264216 Kb 667.0 nM
O=C(O)/C=C/c1ccccc1/C=C/Cc1ccccc1OCc1ccccc1 CHEMBL1237297 Ki 680.0 nM
COc1cc(CC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC CHEMBL3264222 Kb 680.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(CN)cc1 CHEMBL3286672 Kb 690.0 nM
COc1cc(-c2cccc(Cl)c2)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586333 IC50 700.0 nM
COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1ccccn1)C2 CHEMBL3586310 IC50 700.0 nM
CCCCCC(O)c1ccc([C@H]2CCC(=O)[C@@H]2C/C=C\CCCC(=O)O)cc1 CHEMBL3920796 Ki 700.0 nM
CC(C)(CO)c1ccc([C@@H]2[C@@H](CCCCCCC(=O)O)[C@H](Cl)C[C@H]2O)cc1 CHEMBL3922121 EC50 708.0 nM
C[C@H](NC(=O)c1cc(Cl)ccc1Oc1ccc(F)cc1)c1ccc(C(=O)O)cc1 CHEMBL591666 IC50 709.0 nM
CCCCCC(O)c1ccc(N2C(=O)CC[C@@H]2COc2ccc(C(=O)O)cc2)cc1 CHEMBL3901873 EC50 728.0 nM
O=C(O)CCCCCC[C@@H]1[C@@H](c2ccc(C3(O)CCC3)cc2)[C@H](O)C[C@H]1Cl CHEMBL3968751 EC50 743.0 nM
C[C@@H](CCc1ccccc1)[C@@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3966743 EC50 743.0 nM
C[C@H](NC(=O)c1c(Cl)sc(Cl)c1Cc1cccc(Cl)c1)c1ccc(C(=O)O)cc1 CHEMBL599052 Ki 746.0 nM
C/C(=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1)c1ccccc1 CHEMBL248679 Ki 749.0 nM
COc1cc(/C=C\Cc2ccccc2/C=C/C(=O)O)ccc1OCc1ccccc1 CHEMBL1237317 Ki 750.0 nM
COc1cc(/C=C/Cc2ccccc2/C=C/C(=O)O)ccc1OCc1ccccc1 CHEMBL218626 Ki 750.0 nM
CCC#CC[C@H](C)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3949856 EC50 763.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1cccc(N2CCN(C)CC2)c1 CHEMBL3286652 Kb 770.0 nM
CC(C)(C)C(O)c1ccc([C@@H]2[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]2O)cc1 CHEMBL3920560 EC50 779.0 nM
Cc1sc(C)c(C(=O)N[C@@H](C)c2ccc(C(=O)O)cc2)c1Cc1cccc(C(F)(F)F)c1 CHEMBL605330 Ki 800.0 nM
CCN(CC)C(=O)c1ccc(C(=O)NCCn2c(C)cc3ccccc32)cc1 CHEMBL3286647 Kb 800.0 nM
COc1cc(-n2ccc3ccc(Cl)cc32)cc2c1OCCN(Cc1cccnc1)C2 CHEMBL3586343 IC50 800.0 nM
CCCC/C=C(C)/C=C\[C@H]1CCC(=O)N1CCc1ccc(C(=O)O)cc1 CHEMBL2096894 Ki 802.0 nM
O=C(O)CCCCCC[C@@H]1[C@@H](c2ccc3c(c2)CCC3)[C@H](O)C[C@H]1Cl CHEMBL3976116 EC50 818.0 nM
O=C(O)/C=C/c1ccccc1-c1cccc(-c2ccccc2OCc2ccccc2)c1 CHEMBL340501 Ki 830.0 nM
O=C(CCc1ccc(Cl)cc1CN1CCC[C@H]1c1nc(C(=O)NCCCCC2CCCCC2)co1)NS(=O)(=O)C(F)(F)F CHEMBL3942394 EC50 830.0 nM
Cc1ccc(OCc2ccccc2)c(/C=C/Cc2ccccc2/C=C/C(=O)O)c1 CHEMBL218123 Ki 860.0 nM
Cc1ccc(OCc2ccccc2)c(C/C=C/c2ccccc2/C=C/C(=O)O)c1 CHEMBL376053 Ki 860.0 nM
C[C@H](NC(=O)c1c(C(F)F)nn(C)c1Oc1cccc(C(F)(F)F)c1)c1ccc(C(=O)O)cc1 CHEMBL3670685 IC50 928.2 nM
COC(=O)CCCCCC[C@H]1C(=O)C[C@@H](O)[C@@H]1c1ccc(C(C)(C)C)cc1 CHEMBL3915820 EC50 936.0 nM
Cc1cccc(CCCc2ccccc2CCC(=O)O)c1OCc1ccccc1 CHEMBL180343 Ki 940.0 nM
Cc1ccc(OCc2ccccc2)c(CCCc2ccccc2CCC(=O)O)c1 CHEMBL220820 Ki 940.0 nM
CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C(=O)C(C)(C)[C@H]1O CHEMBL3895324 EC50 944.0 nM
Cc1cc2ccccc2n1CCNC(=O)c1ccc(CN2CCOCC2)cc1 CHEMBL3286708 Kb 970.0 nM
Cc1cccc(C2CC2c2ccccc2CCC(=O)O)c1OCc1ccccc1 CHEMBL180752 Ki 990.0 nM
C[C@@H](Cc1ccccc1)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 CHEMBL3902065 EC50 1000.0 nM