O=C(O)CCCC[C@@H]1CCSS1 CHEMBL134342 IC50 0.0 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 IC50 0.0 nM
Clc1ccc(-c2cn[se]c2-c2ccc(Cl)cc2)cc1 CHEMBL501676 IC50 0.0 nM
Cc1ccc(-c2[se]ncc2-c2ccc(Cl)cc2)cc1 CHEMBL471171 IC50 0.0 nM
Cc1ccc(-c2cn[se]c2-c2ccc(Cl)cc2)cc1 CHEMBL513405 IC50 0.0 nM
COc1ccc(-c2[se]ncc2-c2ccc(C)cc2)cc1 CHEMBL452730 IC50 0.0 nM
CC(Oc1cc(=O)oc2ccccc12)C(=O)N1CCCC1 CHEMBL2158361 IC50 0.0 nM
COc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1 CHEMBL499068 pIC50 0.005998 nM
[11CH3]Oc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1 CHEMBL5196097 IC50 0.006 nM
COc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)[nH]c3ccccc23)cc1 CHEMBL499069 IC50 0.02 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(F)cc2)cc1 CHEMBL501208 IC50 0.02 nM
Cc1ccc2[nH]c(-c3ccc(S(N)(=O)=O)cc3)c(-c3ccccc3)c2c1 CHEMBL525247 IC50 0.02 nM
Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1 CHEMBL502555 pIC50 0.06998 nM
Fc1ccc(-c2[nH]c(-c3ccc(F)cc3)c3c2C2CCC3C2)cc1 CHEMBL143776 IC50 0.08 nM
Cc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)[nH]c3ccccc23)cc1 CHEMBL524543 pIC50 0.08995 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccccc2)cc1 CHEMBL500936 pIC50 0.08995 nM
Fc1ccc(-c2[nH]c(-c3ccc(F)cc3)c3c2C2CCC3CC2)cc1 CHEMBL140167 IC50 0.12 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccccc2)cc1 CHEMBL499349 IC50 0.14 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL6 IC50 0.14 nM
Cc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)[nH]c3ccccc23)cc1C CHEMBL525021 pIC50 0.1698 nM
CC(=O)NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccccc2)cc1 CHEMBL500943 pIC50 0.1799 nM
N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)O CHEMBL1957450 Kd 0.19 nM
CC(C)Cc1ccc(C(C)C(=O)Oc2ccc(CCO)cc2)cc1 CHEMBL1958349 IC50 0.2 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NCc3ccccc3)n2)cc1 CHEMBL551829 IC50 0.25 nM
Cc1ccc2[nH]c(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccccc3)c2c1 CHEMBL525250 pIC50 0.2799 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NCc3ccc(F)cc3)n2)cc1 CHEMBL551148 IC50 0.28 nM
COc1ccc2c(c1)c(Cc1nc(-c3ccc(Br)cc3)cs1)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL423296 IC50 0.3 nM
CCOc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL271173 IC50 0.3 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccccc2)cc1 CHEMBL502285 pIC50 0.3597 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(Br)cc2)cc1 CHEMBL502554 pIC50 0.3698 nM
COc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL270293 IC50 0.4 nM
CCOc1ccc(-c2nn3ncccc3c2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL186632 IC50 0.44 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(Cl)cc2)cc1 CHEMBL282093 IC50 0.45 nM
Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL118 Ki 0.47 nM
Cc1cnc(NC(=O)C2=C(O)c3ccccc3S(=O)(=O)N2C)s1 CHEMBL599 IC50 0.49 nM
COc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CCC2)cc1 CHEMBL108201 IC50 0.5 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NC3CCCCC3)n2)cc1 CHEMBL561891 IC50 0.5 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccc(Cl)cc2)cc1 CHEMBL500674 pIC50 0.5395 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccccc2)cc1 CHEMBL499070 pIC50 0.5998 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2cccc(Cl)c2)cc1 CHEMBL500675 pIC50 0.7998 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)cc3)CC3(CC3)C2)cc1 CHEMBL327384 pIC50 1.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)cc3)CC3(CC3)C2)cc1 CHEMBL88717 pIC50 1.0 nM
COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1 CHEMBL432945 pIC50 1.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)c(Cl)c3)CC3(CC3)C2)cc1 CHEMBL313387 pIC50 1.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccccc3)C(=O)OC2)cc1 CHEMBL122 IC50 1.0 nM
CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1OC1CCCCC1 CHEMBL7162 IC50 1.0 nM
COc1ccc2c(c1)c(Cc1nc(-c3csc4ccccc34)cs1)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL28155 IC50 1.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(C(F)(F)F)cc3)CC3(CC3)C2)cc1 CHEMBL330314 IC50 1.0 nM
O=C1NC(=O)C(=Cc2cn(C[C@H](O)COc3cc(O)c4c(=O)cc(-c5ccccc5)oc4c3)c3ccccc23)C(=O)N1 CHEMBL5089355 IC50 1.0 nM
CS(=O)(=O)c1ccc(-c2cc(O[11CH3])nc(NCc3cccs3)n2)cc1 CHEMBL5200454 IC50 1.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CC3)C2)cc1 CHEMBL92154 IC50 1.1 nM
Cc1ccc(-c2cc(C)n(S(=O)(=O)Oc3ccccc3)n2)cc1 CHEMBL4851853 IC50 1.1 nM
C=C1CC(c2ccc(S(C)(=O)=O)cc2)=C1c1ccccc1 CHEMBL91118 IC50 1.2 nM
CCSc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL272433 IC50 1.2 nM
CS(=O)(=O)c1ccc(-c2nc(Cl)cc(NCc3cccs3)n2)cc1 CHEMBL270078 IC50 1.2 nM
CC(=O)Oc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)COC2=O)cc1 CHEMBL93372 IC50 1.26 nM
COc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CC3(CC3)C2)cc1Br CHEMBL86363 pIC50 1.288 nM
CCCCNc1nc(-c2ccc(S(C)(=O)=O)cc2)cc(C(F)(F)F)n1 CHEMBL549393 IC50 1.3 nM
O=C1/C(=C/c2coc3ccccc3c2=O)c2ccccc2N1c1c(Cl)cccc1Cl CHEMBL3314084 IC50 1.3 nM
O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl CHEMBL1034 IC50 1.3 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccc(Br)cc3c2-c2ccccc2)cc1 CHEMBL527107 pIC50 1.409 nM
Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1C CHEMBL502556 pIC50 1.459 nM
Cc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CC3(CC3)C2)cc1 CHEMBL92102 IC50 1.5 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(F)c(Cl)c3)CC3(CC3)C2)cc1 CHEMBL312822 IC50 1.5 nM
CC(=O)Oc1cccc(C2=C(c3ccc(S(C)(=O)=O)cc3)COC2=O)c1 CHEMBL93024 IC50 1.68 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(F)c2-c2ccccc2)cc1 CHEMBL29766 IC50 1.7 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c([18F])c2-c2ccccc2)cc1 CHEMBL5208551 IC50 1.7 nM
O=C1OCC(c2ccc(-c3nn[nH]n3)cc2)=C1c1ccccc1 CHEMBL214101 IC50 1.8 nM
Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(-c3nn[nH]n3)cc2)cc1 CHEMBL213338 IC50 1.9 nM
COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CCC2)cc1 CHEMBL111562 pIC50 1.995 nM
COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1Br CHEMBL313313 pIC50 1.995 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc4c(c3)OCO4)CCC2)cc1 CHEMBL424063 pIC50 1.995 nM
COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1F CHEMBL88532 pIC50 1.995 nM
Cc1cc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)ccc1F CHEMBL52020 pIC50 1.995 nM
CN(C)c1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CCC2)cc1Cl CHEMBL111356 pIC50 1.995 nM
NS(=O)(=O)c1ccc(-c2cc(F)c(F)cc2-c2ccc(F)c(Cl)c2)cc1 CHEMBL52820 pIC50 1.995 nM
COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1Cl CHEMBL315585 pIC50 1.995 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)c(Cl)c3)CCC2)cc1 CHEMBL111321 pIC50 1.995 nM
NS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2-c2ccc(F)c(Cl)c2)cc1 CHEMBL362779 -Log IC50 1.995 nM
Cc1cc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)ccc1F CHEMBL365301 -Log IC50 1.995 nM
CCOc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL324312 IC50 2.0 nM
NS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2cc(Cl)cc(Cl)c2)cc1 CHEMBL419407 IC50 2.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(C(F)(F)F)cc3)CC3(CC3)C2)cc1 CHEMBL329999 IC50 2.0 nM
CS(=O)(=O)c1ccc(-c2cc(Br)sc2-c2ccc(F)cc2)cc1 CHEMBL42485 IC50 2.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CCC3)C2)cc1 CHEMBL171335 IC50 2.0 nM
CS(=O)(=O)c1ccc(-c2c(-c3ccccc3)nn3ncccc23)cc1 CHEMBL365865 IC50 2.0 nM
NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2CF)cc1 CHEMBL371477 IC50 2.0 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccc(F)cc3c2-c2ccccc2)cc1 CHEMBL499348 IC50 2.0 nM
CCC(C)Nc1nc(-c2ccc(S(C)(=O)=O)cc2)cc(C(F)(F)F)n1 CHEMBL539663 IC50 2.0 nM
COc1ccc(-n2c(-c3ccc(S(C)(=O)=O)cc3)cc(CC(=O)OCCCO[N+](=O)[O-])c2C)cc1 CHEMBL1939677 IC50 2.0 nM
CS(=O)(=O)c1ccc(-c2cc(F)c(F)cc2-c2ccc(F)c(Cl)c2)cc1 CHEMBL52760 IC50 2.0 nM
CN1C/C(=C\c2cccs2)C2=NN(c3ccccc3)C(c3cccs3)C2C1 CHEMBL316846 IC50 2.0 nM
CN1C/C(=C\c2ccc(Br)s2)C2=NN(c3ccccc3)C(c3ccc(Br)s3)C2C1 CHEMBL5267453 IC50 2.0 nM
CN1C/C(=C\c2ccc(Cl)s2)C2=NN(c3ccccc3)C(c3ccc(Cl)s3)C2C1 CHEMBL5279940 IC50 2.0 nM
CN1C/C(=C\c2ccc(F)s2)C2=NN(c3ccccc3)C(c3ccc(F)s3)C2C1 CHEMBL5277168 IC50 2.0 nM
Cc1ccc(/C=C2\CN(C)CC3C2=NN(c2ccccc2)C3c2ccc(C)s2)s1 CHEMBL5280463 IC50 2.0 nM
CN1C/C(=C\c2ccc(O)s2)C2=NN(c3ccccc3)C(c3ccc(O)s3)C2C1 CHEMBL5265839 IC50 2.0 nM
CCc1ccc(/C=C2\CN(C)CC3C2=NN(c2ccccc2)C3c2ccc(CC)s2)s1 CHEMBL5289245 IC50 2.0 nM
CN1C/C(=C\c2ccc([N+](=O)[O-])s2)C2=NN(c3ccccc3)C(c3ccc([N+](=O)[O-])s3)C2C1 CHEMBL5269974 IC50 2.0 nM
Cc1sc(/C=C2\CN(C)CC3C2=NN(c2ccccc2)C3c2cc(Br)c(C)s2)cc1Br CHEMBL5290253 IC50 2.0 nM
Cc1csc(/C=C2\CN(C)CC3C2=NN(c2ccccc2)C3c2cc(C)cs2)c1 CHEMBL5276070 IC50 2.0 nM
Cc1sc(/C=C2\CN(C)CC3C2=NN(c2ccccc2)C3c2cc(F)c(C)s2)cc1F CHEMBL5278033 IC50 2.0 nM
CS(=O)(=O)c1ccc(C(=O)OCCn2cc(-c3ccc(C(F)(F)F)cc3)nn2)cc1 CHEMBL5283867 IC50 2.0 nM
CS(=O)(=O)c1ccc(-c2nc(NCc3cccs3)cc(C(F)(F)F)n2)cc1 CHEMBL271338 IC50 2.1 nM
C=C1C(c2ccccc2)=C(c2ccc(S(C)(=O)=O)cc2)C1(C)C CHEMBL92443 IC50 2.2 nM
COCCOc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL271549 IC50 2.4 nM
NS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NC3CCCCC3)n2)cc1 CHEMBL561609 IC50 2.4 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc4c(c3)OCO4)CC3(CC3)C2)cc1 CHEMBL88549 IC50 2.5 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CCC2)cc1 CHEMBL274893 IC50 2.6 nM
CS(=O)(=O)c1ccc(C2=CC3(C=C2c2ccc(F)cc2)CC3)cc1 CHEMBL89429 IC50 2.6 nM
CC1(C)C(=O)C(c2ccccc2)=C1c1ccc(S(C)(=O)=O)cc1 CHEMBL420987 IC50 2.8 nM
Cc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL332251 IC50 3.0 nM
CS(=O)(=O)c1ccc(-c2cnn(Cc3ccccc3)c(=O)c2OCC2CC2)cc1 CHEMBL155898 IC50 3.0 nM
Cc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CCC2)cc1 CHEMBL127674 IC50 3.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)cc3)CCC2)cc1 CHEMBL340573 IC50 3.0 nM
Cc1ccc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)cc1Cl CHEMBL298476 IC50 3.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)cc3)CCC2)cc1 CHEMBL111590 IC50 3.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(Cl)c(Cl)c3)CC3(CC3)C2)cc1 CHEMBL558340 IC50 3.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(F)c(F)c3)CC3(CC3)C2)cc1 CHEMBL314225 IC50 3.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CC3)C2)cc1 CHEMBL17184 IC50 3.0 nM
Cc1cc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)ccc1Cl CHEMBL55805 IC50 3.0 nM
Cc1ccc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1Cl CHEMBL54327 IC50 3.0 nM
CS(=O)(=O)c1ccc(-c2sc3nc(C(F)(F)F)nn3c2-c2ccccc2)cc1 CHEMBL156482 IC50 3.0 nM
Cc1cccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)sc3nc(C(F)(F)F)nn23)c1 CHEMBL421826 IC50 3.0 nM
CCOc1ccc(-c2nn3ncccc3c2-c2ccc(S(C)(=O)=O)cc2)cc1 CHEMBL364804 IC50 3.0 nM
Cc1ccc(N(C)c2nc(-c3ccc(S(C)(=O)=O)cc3)cc(C(F)(F)F)n2)cc1 CHEMBL559613 IC50 3.0 nM
O=C(O)C1=Cc2c(ccc(Cl)c2Cl)OC1C(F)(F)F CHEMBL1288533 IC50 3.0 nM
CCCCOc1nc(OCC2(O)CCC2)c(-c2ccc(S(C)(=O)=O)cc2)cc1CO CHEMBL4870569 Ki 3.0 nM
Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1Cl CHEMBL185547 -Log IC50 3.02 nM
Cc1cc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)ccc1Cl CHEMBL185196 -Log IC50 3.02 nM
Cc1ccc(Sc2ccccc2N2CCNCC2)c(C)c1 CHEMBL2104993 IC50 3.11 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2cccc(Cl)c2)cc1 CHEMBL524542 IC50 3.13 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(F)c(F)c3)CC3(CC3)C2)cc1 CHEMBL92107 IC50 3.3 nM
CC(=O)Oc1ccccc1C1=C(c2ccc(S(C)(=O)=O)cc2)COC1=O CHEMBL328616 IC50 3.5 nM
CC(C)(C)c1cc(/C=C2\CCOC2=O)cc2c1OCC2(C)C CHEMBL2112567 IC50 3.5 nM
CSc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1C CHEMBL28913 IC50 3.7 nM
Cc1ccc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL54370 pIC50 3.981 nM
NS(=O)(=O)c1ccc(-c2cc(F)c(F)cc2-c2ccc(F)cc2)cc1 CHEMBL296384 pIC50 3.981 nM
NS(=O)(=O)c1ccc(-c2cc(F)c(F)cc2-c2ccc3c(c2)OCO3)cc1 CHEMBL300600 pIC50 3.981 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CCC3)C2)cc1 CHEMBL90447 pIC50 3.981 nM
COc1c(Cl)cc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1Cl CHEMBL88493 pIC50 3.981 nM
NS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2-c2ccc(F)cc2)cc1 CHEMBL185163 -Log IC50 3.981 nM
NS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2-c2ccc3c(c2)OCO3)cc1 CHEMBL365883 -Log IC50 3.981 nM
Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1 CHEMBL184076 -Log IC50 3.981 nM
CCOc1ccc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)cc1 CHEMBL324509 IC50 4.0 nM
COc1ccc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)cc1F CHEMBL117862 IC50 4.0 nM
O=C(O)Cn1nncc1CO[C@@H](C(=O)O)[C@@H](OCc1cnnn1CC(=O)O)C(=O)O CHEMBL5077595 IC50 4.0 nM
[11CH3]Oc1ccc(-c2cnc(Cl)n2-c2ccc(S(N)(=O)=O)cc2)cc1F CHEMBL5178995 IC50 4.0 nM
CS(=O)(=O)c1ccc(-c2nc(SCc3cccs3)cc(C(F)(F)F)n2)cc1 CHEMBL270294 IC50 4.1 nM
CC1C(c2ccccc2)=C(c2ccc(S(C)(=O)=O)cc2)ON1C CHEMBL444805 IC50 4.2 nM
CN(C)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL28881 pIC50 4.677 nM
Nc1c(CC(=O)O)cccc1C(=O)c1ccc(Br)cc1 CHEMBL1077 IC50 4.803 nM
CC1(C)C(=O)C(c2ccc(F)cc2)=C1c1ccc(S(C)(=O)=O)cc1 CHEMBL91832 IC50 5.0 nM
COc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1F CHEMBL435381 IC50 5.0 nM
COc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1Cl CHEMBL115979 IC50 5.0 nM
COc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)oc3ccccc23)cc1F CHEMBL76692 IC50 5.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)c3ccccc3C2)cc1 CHEMBL80405 IC50 5.0 nM
Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1 CHEMBL865 IC50 5.0 nM
CN(C)c1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CCC2)cc1Cl CHEMBL109623 IC50 5.0 nM
COc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CC3(CC3)C2)cc1 CHEMBL89089 IC50 5.0 nM
Cc1cc(-c2cc(F)c(F)cc2-c2ccc(S(C)(=O)=O)cc2)ccc1F CHEMBL443791 IC50 5.0 nM
Cc1ccc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1C CHEMBL54326 IC50 5.0 nM
COc1ccc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1C CHEMBL51860 IC50 5.0 nM
Cc1nc(-c2ccc(Cl)cc2)c(-c2ccc(S(N)(=O)=O)cc2)s1 CHEMBL278492 IC50 5.0 nM
O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl CHEMBL139 IC50 5.0 nM
CS(=O)(=O)c1ccc(-c2[nH]c3ccc(F)cc3c2-c2ccccc2)cc1 CHEMBL525246 IC50 5.0 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Br)cc3c2-c2ccccc2)cc1 CHEMBL502286 IC50 5.0 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NCC3CCOCC3)n2)cc1 CHEMBL563322 IC50 5.0 nM
CCCNc1nc(-c2ccc(S(C)(=O)=O)cc2)cc(C(F)(F)F)n1 CHEMBL558728 IC50 5.0 nM
CC(C)(C)c1cc2c(cc1Cl)C=C(C(=O)O)C(C(F)(F)F)O2 CHEMBL1630225 IC50 5.0 nM
CCCc1cc2c(cc1Cl)C=C(C(=O)O)[C@H](C(F)(F)F)O2 CHEMBL1630249 IC50 5.0 nM
Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)NCC(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)O)c3ccccc32)cc1 CHEMBL3576974 Ki 5.0 nM
CCC(=O)NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1 CHEMBL1206690 IC50 5.0 nM
CS(=O)(=O)c1ccc(-n2c(-c3ccc(O[11CH3])c(F)c3)cnc2Cl)cc1 CHEMBL5169729 IC50 5.0 nM
Cc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)cn3c2CCC3)cc1 CHEMBL597733 IC50 5.0 nM
Cc1cc(-c2c(-c3ccc(S(C)(=O)=O)cc3)ccc(F)c2F)ccc1F CHEMBL188071 -Log IC50 5.012 nM
COc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1C CHEMBL184341 -Log IC50 5.012 nM
Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1C CHEMBL184375 -Log IC50 5.012 nM
COc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL271932 IC50 5.1 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(F)cc2)cc1 CHEMBL499347 IC50 5.15 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(Cl)c2-c2ccc(Cl)cc2)cc1 CHEMBL280636 pIC50 5.248 nM
CC(C(=O)O)c1ccc2c(c1)[nH]c1ccc(Cl)cc12 CHEMBL1316 IC50 5.3 nM
CS(=O)(=O)c1ccc(-c2nc(NCc3ccc(Cl)s3)cc(C(F)(F)F)n2)cc1 CHEMBL403957 IC50 5.4 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(Nc3ccccc3)n2)cc1 CHEMBL561950 IC50 5.6 nM
Cc1ccnc(C(=O)c2[nH]c3ccc(F)cc3c2CC(=O)O)c1 CHEMBL1950017 IC50 5.68 nM
CN(C)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1F CHEMBL29899 IC50 5.7 nM
CC(C)c1ccc2occ(/C=C3/C(=O)N(c4c(Cl)cccc4Cl)c4ccccc43)c(=O)c2c1 CHEMBL3314086 IC50 5.8 nM
Cc1cc(-c2ccccn2)nn1S(=O)(=O)Oc1ccc(Cl)cc1 CHEMBL4858751 IC50 5.8 nM
CS(=O)(=O)c1ccc(-c2nc(NCc3cc4ccccc4s3)cc(C(F)(F)F)n2)cc1 CHEMBL273118 IC50 5.92 nM
Cc1ccc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)cc1F CHEMBL325298 IC50 6.0 nM
CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2cccc(Cl)c2Cl)cc1 CHEMBL324826 IC50 6.0 nM
CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccc3c(c2)OCO3)cc1 CHEMBL326335 IC50 6.0 nM
CS(=O)(=O)c1ccc(-c2nc(C(F)(F)F)sc2-c2ccc(F)cc2)cc1 CHEMBL17047 IC50 6.0 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c3c2-c2cc(F)c(F)cc2CS3)cc1 CHEMBL97059 IC50 6.0 nM
COc1c(Cl)cc(C2=C(c3ccc(S(C)(=O)=O)cc3)CC3(CC3)C2)cc1Cl CHEMBL315520 IC50 6.0 nM
NS(=O)(=O)c1ccc(-c2ccccc2-c2ccc(Cl)cc2)cc1 CHEMBL52402 IC50 6.0 nM
CN(C)c1ccc(-c2cc(F)c(F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1Cl CHEMBL52872 IC50 6.0 nM
Cc1cc(-c2cc(F)c(F)cc2-c2ccc(S(C)(=O)=O)cc2)ccc1Cl CHEMBL57837 IC50 6.0 nM
C=Cc1nc2sc(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccccc3)n2n1 CHEMBL157714 IC50 6.0 nM
CS(=O)(=O)c1ccc(C2=C(C#Cc3ccccc3)C(=O)CC2)cc1 CHEMBL278336 IC50 6.0 nM
CS(=O)(=O)c1ccc(C2=C(c3cc(Cl)c(Cl)c(Cl)c3)C(=O)CC2)cc1 CHEMBL278392 IC50 6.0 nM
O=C(O)C1=Cc2c(cc(Cl)c(Cl)c2Cl)OC1C(F)(F)F CHEMBL1288592 IC50 6.0 nM
CN1C(=O)C(c2ccc(Cl)cc2)=C(c2ccc(S(N)(=O)=O)cc2)C1=O CHEMBL3233602 IC50 6.0 nM
COc1ccccc1-n1cc(COC(=O)C2CCn3c(C(=O)c4ccccc4)ccc32)nn1 CHEMBL4067898 IC50 6.0 nM
Cc1cc(-c2c(-c3ccc(S(C)(=O)=O)cc3)ccc(F)c2F)ccc1Cl CHEMBL182695 -Log IC50 6.026 nM
CN(C)c1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1Cl CHEMBL363270 -Log IC50 6.026 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c3c2-c2ccc(F)c(F)c2CS3)cc1 CHEMBL363574 Log IC50 6.026 nM
CCN(CC)c1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL259468 IC50 6.1 nM
Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)NCC(=O)O)c3ccccc32)cc1 CHEMBL3576979 IC50 6.3 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(O)cc2)cc1 CHEMBL526370 IC50 6.44 nM
COc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL29583 IC50 6.7 nM
Cc1ccnc(C(=O)c2[nH]c3cc(Cl)c(F)cc3c2CC(=O)O)c1 CHEMBL1950016 IC50 6.77 nM
Cc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)ccc(F)c2F)cc1 CHEMBL365622 -Log IC50 6.918 nM
CCOc1ccc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)cc1Cl CHEMBL327150 IC50 7.0 nM
CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccc(F)cc2F)cc1 CHEMBL115752 IC50 7.0 nM
COc1c(Cl)cc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)cc1Cl CHEMBL116016 IC50 7.0 nM
CCOc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1Cl CHEMBL117917 IC50 7.0 nM
CS(=O)(=O)c1ccc(-c2sc(CCCc3ccc(Br)cc3)nc2-c2ccc(F)cc2)cc1 CHEMBL16516 IC50 7.0 nM
NS(=O)(=O)c1ccc(-c2oc3ccccc3c2-c2ccc(F)cc2)cc1 CHEMBL77714 IC50 7.0 nM
CC1(C)CC(c2ccc(Cl)cc2)=C(c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL320784 IC50 7.0 nM
NS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2cccc(Br)c2)cc1 CHEMBL46584 IC50 7.0 nM
NS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CCC2)cc1 CHEMBL265562 IC50 7.0 nM
COc1ccc2c(c1)c(Cc1nc(-c3ccc([N+](=O)[O-])cc3)cs1)c(C)n2C(=O)c1ccc(Br)cc1 CHEMBL26829 IC50 7.0 nM
COc1ccc2c(c1)c(Cc1nc(-c3ccc4ccccc4c3)cs1)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL282015 IC50 7.0 nM
COc1ccc2c(c1)c(Cc1nc(-c3ccc(Cl)cc3)cs1)c(C)n2C(=O)c1ccc(Br)cc1 CHEMBL28220 IC50 7.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(F)c(Cl)c3)CC3(CC3)C2)cc1 CHEMBL88286 IC50 7.0 nM
Cc1ccc(-c2cc(F)c(F)cc2-c2ccc(S(C)(=O)=O)cc2)cc1 CHEMBL293771 IC50 7.0 nM
CC(C)(C)c1cc(C(=O)c2ccccc2)cc2c1OCC2(C)C CHEMBL275120 IC50 7.0 nM
CN1C(O)=C(C(=O)Nc2ccc(Br)cc2Br)c2cc(Cl)ccc2S1(=O)=O CHEMBL173724 IC50 7.0 nM
Cc1ccc(Nc2c(F)cccc2Cl)c(CC(=O)O)c1 CHEMBL404108 IC50 7.0 nM
CC(C)Cc1cc2c(cc1Cl)C=C(C(=O)O)[C@H](C(F)(F)F)O2 CHEMBL1630251 IC50 7.0 nM
Cc1c(CC(=O)OCCCO[N+](=O)[O-])cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1cccc(F)c1 CHEMBL1939671 IC50 7.0 nM
COc1ccc(N2CCN(CCc3c(C)nc4oc(-c5ccccc5)nn4c3=O)CC2)cc1 CHEMBL4849659 IC50 7.0 nM
CC(C)(C)c1cc(-c2cc(=S)ss2)cc(C(C)(C)C)c1O CHEMBL462911 IC50 7.2 nM
CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(Nc3ccc(F)cc3)n2)cc1 CHEMBL561086 IC50 7.2 nM
CS(=O)(=O)c1ccc(-c2nc(NCc3cccs3)cc(OC3CCCC3)n2)cc1 CHEMBL271348 IC50 7.5 nM
COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL29839 pIC50 7.943 nM
CN(C)c1ccc(-c2cc(F)c(F)cc2-c2ccc(S(C)(=O)=O)cc2)cc1Cl CHEMBL299806 pIC50 7.943 nM
NS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2cccc(Cl)c2)cc1 CHEMBL298269 pIC50 7.943 nM
CN(C)c1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)ccc(F)c2F)cc1Cl CHEMBL364598 -Log IC50 7.943 nM
COc1cc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)ccc1F CHEMBL116683 IC50 8.0 nM
COc1ccc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)cc1Cl CHEMBL117295 IC50 8.0 nM
NS(=O)(=O)c1ccc(-c2cscc2-c2ccc(F)cc2)cc1 CHEMBL316823 IC50 8.0 nM
COc1ccc2c(c1)c(Cc1nc(-c3cccc(Br)c3)cs1)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL24407 IC50 8.0 nM
CN1C(O)=C(C(=O)Nc2ccccc2Cl)c2cc(Cl)ccc2S1(=O)=O CHEMBL173072 IC50 8.0 nM
NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2CCF)cc1 CHEMBL196041 IC50 8.0 nM
CC(C)CSc1cc2c(cc1Cl)C=C(C(=O)O)[C@H](C(F)(F)F)O2 CHEMBL1630253 IC50 8.0 nM
NS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2ccc3c(c2)OCCO3)cc1 CHEMBL3309445 IC50 8.0 nM
O=C(O)C1=Cc2cc(S(F)(F)(F)(F)F)cc(Br)c2O[C@@H]1C(F)(F)F CHEMBL4084676 IC50 8.0 nM
[11CH3]Oc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL5191675 IC50 8.0 nM
CS(=O)(=O)c1ccc(-c2cn3c(c2-c2ccc(Cl)cc2)CCC3)cc1 CHEMBL5269462 IC50 8.0 nM
NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(Br)cc2)cc1 CHEMBL499041 pIC50 8.356 nM
C=C1CCCC2C1(C)CCC(C)C2(C)CCC1=CC(=O)OC1O CHEMBL5290007 IC50 8.49 nM
COc1c(Cl)cc(C2=C(c3ccc(S(N)(=O)=O)cc3)CCC2)cc1Cl CHEMBL321643 pIC50 8.913 nM
COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CCC2)cc1Cl CHEMBL111095 pIC50 8.913 nM
COc1ccc2c(c1F)CSc1c(C(F)(F)F)nn(-c3ccc(S(N)(=O)=O)cc3)c1-2 CHEMBL365769 Log IC50 8.913 nM
COc1cc2c(cc1F)-c1c(c(C(F)(F)F)nn1-c1ccc(S(N)(=O)=O)cc1)SC2 CHEMBL328009 pIC50 8.999 nM
CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccc3c(c2)CCO3)cc1 CHEMBL325894 IC50 9.0 nM
NS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccccc2)cc1 CHEMBL118064 IC50 9.0 nM
COc1ccc(-c2cscc2-c2ccc(S(N)(=O)=O)cc2)cc1F CHEMBL97874 IC50 9.0 nM
CSc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL283178 IC50 9.0 nM
CS(=O)(=O)c1ccc(C2=C(c3ccc(F)c(Cl)c3)C(=O)CC2)cc1 CHEMBL23808 IC50 9.0 nM
NS(=O)(=O)c1ccc(-c2sc(COc3cc(Cl)cc(Cl)c3)nc2-c2ccc(F)cc2)cc1 CHEMBL276324 IC50 9.0 nM
CN1C(O)=C(C(=O)Nc2ccc(Cl)cc2Cl)c2cc(Cl)ccc2S1(=O)=O CHEMBL174777 IC50 9.0 nM
[2H]C([2H])([2H])c1cc2c(c(C([2H])([2H])[2H])c1Br)C=C(C(=O)O)[C@@H](C(F)(F)F)O2 CHEMBL3355612 IC50 9.0 nM
CS(=O)(=O)c1ccc(-c2nccc(NCc3cccs3)n2)cc1 CHEMBL405564 IC50 9.2 nM
Cc1ccc(-c2cc(C)n(S(=O)(=O)Oc3ccc(I)cc3)n2)cc1 CHEMBL4871081 IC50 9.2 nM
COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1C CHEMBL29887 IC50 9.3 nM
NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(Br)cc2)cc1 CHEMBL1235806 IC50 9.3 nM
CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)OCC3 CHEMBL622 IC50 9.4 nM
CC(C)c1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 CHEMBL271104 IC50 9.8 nM
O=C(O)C1=Cc2cc(Cl)cc(Cl)c2O[C@@H]1C(F)(F)F CHEMBL1230348 IC50 9.8 nM
Cc1ccnc(C(=O)c2[nH]c3cc(F)ccc3c2CC(=O)O)c1 CHEMBL1950009 IC50 9.81 nM