C=C1C(=O)N[C@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(=O)O)[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](/C=C/C(C)=C/[C@H](C)[C@H](Cc2ccccc2)OC)[C@H](C)C(=O)N[C@@H](C(=O)O)CCC(=O)N1C CHEMBL444092 IC50 0.1 nM
COC[C@@H]([C@H](O)[C@H](O)C(=O)NCC[C@H](C)c1nc(/C=C/C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C(C)=C/C=C/C(C)=C\C#N)OC)[C@H](OP(=O)(O)O)C3(C)C)co1)N(C)C CHEMBL430266 IC50 0.3 nM
C/C=C1\C(=O)N[C@@H](C(=O)O)[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](/C=C/C(C)=C/[C@H](C)[C@H](Cc2ccccc2)OC)[C@H](C)C(=O)N[C@@H](C(=O)O)CCC(=O)N1C CHEMBL4524071 IC50 0.42 nM
CO[C@H]([C@H](O)CC(=O)[C@@H](C)[C@@H](O)CC[C@@H](C)[C@@H]1O[C@]2(CC[C@@H](C)[C@H](CC[C@H](C)C(C)=O)O2)CC[C@@H]1C)[C@H](OC(=O)C[C@@H](O)C1=C(C)C(=O)OC1=O)C(C)C CHEMBL505512 IC50 0.67 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Cl CHEMBL244563 Ki 0.68 nM
COC(=O)c1c(O)cccc1OC/C=C/c1cccc(-c2onc(C(=O)O)c2CO)c1 CHEMBL184444 Ki 0.92 nM
CS(=O)(=O)Nc1ccccc1CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL395722 Ki 1.0 nM
O=C1CN(c2c(O)cc3ccc(C4CCN(S(=O)(=O)C5CC5)C4)cc3c2F)S(=O)(=O)N1 CHEMBL5070507 IC50 1.0 nM
C[C@H](O)CCOc1ccc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2c1 CHEMBL5085615 IC50 1.0 nM
O=C1CN(c2c(O)cc3ccc(NCCC4CC4)cc3c2F)S(=O)(=O)N1 CHEMBL5076419 IC50 1.0 nM
C=C1[C@@H](O)[C@@H]2O[C@]3(CC[C@H](/C=C/[C@@H](C)[C@@H]4CC(C)=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CC[C@H]5O)O4)O3)CC[C@H]2O[C@@H]1[C@@H](O)C[C@H](C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C CHEMBL280487 IC50 1.24 nM
NC(=O)[C@@H](CS)NC(=O)CCCCCNC(=O)[C@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)NC(=O)[C@@H](CC(=O)O)NC(=O)Cc1ccc(C(F)(F)P(=O)(O)O)cc1 CHEMBL1235987 Ki 1.4 nM
COC[C@@H]([C@H](O)[C@H](O)C(=O)N[C@H](C)C[C@H](C)c1nc(/C=C/C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)/C=C(C)/C(C)=C/C=C/C(C)=C\C#N)OC)[C@H](OP(=O)(O)O)C3(C)C)co1)N(C)C CHEMBL509059 IC50 1.49 nM
NC(=O)[C@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc(C(F)(F)P(=O)(O)O)cc1 CHEMBL1232186 Ki 1.7 nM
CC(=O)Nc1ccccc1CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL230862 Ki 2.0 nM
Nc1ccccc1CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL230860 Ki 2.0 nM
COC(=O)c1c(O)cccc1OC/C=C/c1cccc(-c2onc(C(=O)O)c2N)c1 CHEMBL186337 Ki 2.1 nM
NC(=O)[C@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)Cc1ccc(C(F)(F)P(=O)(O)O)cc1 CHEMBL326115 Ki 2.4 nM
N[C@@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)O CHEMBL1232859 Ki 2.4 nM
NC(=O)[C@@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)Cc1ccc(C(F)(F)P(=O)(O)O)cc1 CHEMBL5279725 Ki 2.4 nM
O=P(O)(O)c1cccc(-c2ccc(CC(Cc3ccc(C(F)(F)P(=O)(O)O)cc3)(c3ccccc3)n3nnc4ccccc43)cc2)c1 CHEMBL269166 IC50 3.0 nM
Cc1cccc(C)c1NC(=O)N1CCC(CNc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL243268 Ki 3.0 nM
Cc1ccccc1NC(=O)N1CCC(CNc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL397415 Ki 3.0 nM
COc1ccccc1NC(=O)N1CCC(CNc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL243267 Ki 3.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NCC3CCN(C(=O)Nc4ccccc4Cl)CC3)c2)c1Br CHEMBL387614 Ki 4.0 nM
Cc1ccccc1CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL390245 Ki 4.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br CHEMBL541214 Ki 4.0 nM
CCCCCCCCCCCCCCCC(=O)C1=C(O)[C@@H](CO)OC1=O CHEMBL426373 IC50 4.5 nM
COc1cc(CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(C(F)(F)P(=O)(O)O)cc2)C(=O)N[C@@H](CCCCNC(=O)c2ccc(C)c(Br)c2)C(N)=O)ccc1O CHEMBL5423615 IC50 4.7 nM
NC(=O)[C@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccc(C(F)(F)P(=O)(O)O)cc1 CHEMBL3818452 Ki 4.9 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)c(Br)c2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL267488 IC50 5.0 nM
COC(CC(C)C)c1ccc2cc(-c3ccc(CC(Cc4ccc(C(F)(F)P(=O)(O)O)cc4)(c4ccccc4)n4nnc5ccccc54)cc3)cc(P(=O)(O)O)c2n1 CHEMBL266753 IC50 5.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4Cl)CC3)c2)c1Br CHEMBL230645 Ki 5.0 nM
COC(CC(C)C)c1ccc2ccc(-c3ccc(C(Cc4ccc(C(F)(F)P(=O)(O)O)cc4)(c4ccccc4)n4nnc5ccccc54)cc3)c(P(=O)(O)O)c2n1 CHEMBL590235 IC50 5.0 nM
O=C(c1ccccc1)C(Cc1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2c1)(Cc1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2c1)n1nnc2ccccc21 CHEMBL1938814 IC50 5.0 nM
COC(CC(C)C)c1ccc2ccc(-c3ccc(CC(Cc4ccc(C(F)(F)P(=O)(O)O)cc4)(c4ccccc4)n4nnc5ccccc54)cc3)c(P(=O)(O)O)c2n1 CHEMBL4542052 IC50 5.0 nM
COC(CC(C)C)c1ccc2ccc(CC(Cc3ccc(C(F)(F)P(=O)(O)O)cc3)(c3ccccc3)n3nnc4ccccc43)c(P(=O)(O)O)c2n1 CHEMBL5290902 IC50 5.0 nM
O=C(c1ccccc1)C(Cc1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2c1)(c1ccc2cc(C(F)(F)P(=O)(O)O)c(Br)cc2c1)n1nnc2ccccc21 CHEMBL5275241 IC50 5.0 nM
Cc1cccc(C)c1CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL230752 Ki 6.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4C(F)(F)F)CC3)c2)c1Br CHEMBL230751 Ki 6.0 nM
NS(=O)(=O)c1cc(-c2ccc(CSCc3ccc(C(F)(F)P(=O)(O)O)c(Br)c3)cc2)ccc1Br CHEMBL1162223 IC50 6.0 nM
O=C(c1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)c1ccccc1 CHEMBL266056 IC50 6.0 nM
CC(C)OC(=O)c1cc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(C(=O)c2ccccc2)c2ccccc2)ccc1C(F)(F)P(=O)(O)O CHEMBL5285288 IC50 6.0 nM
O=C(c1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)c(Cl)c1)c1ccccc1 CHEMBL428651 IC50 6.0 nM
O=C(c1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)c(Br)c1)c1ccccc1 CHEMBL8758 IC50 6.0 nM
COC(=O)c1c(O)cccc1OC/C=C/c1ccc(F)c(-c2cc(C(=O)O)no2)c1 CHEMBL117869 Ki 6.9 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NCC3CCN(C(=O)Nc4ccccc4)CC3)c2)c1Br CHEMBL230325 Ki 7.0 nM
O=C(O)c1cccc(/C=C/c2ccc3cc(Br)c(C(F)(F)P(=O)(O)O)cc3n2)c1 CHEMBL411295 IC50 7.0 nM
CO[C@@H](CC(C)C)c1ccc2cc(-c3ccc(C[C@](Cc4ccc(C(F)(F)P(=O)(O)O)cc4)(c4ccccc4)n4nnc5ccccc54)cc3)cc(P(=O)(O)O)c2n1 CHEMBL3746639 IC50 7.0 nM
Cc1c(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)sc(C(=O)O)c1OCC(=O)O CHEMBL244361 Ki 8.0 nM
CCCCCCCCCCCCCCCC(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)[C@@H](C)CC)[C@@H](C)CC CHEMBL4592897 Kd 8.38 nM
O=C1CN(c2c(O)cc3ccc(Br)cc3c2F)S(=O)(=O)N1 CHEMBL5415903 IC50 8.39 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc3cc(F)c(C(F)(F)P(=O)(O)O)cc3c2)cc1 CHEMBL1938828 IC50 9.0 nM
O=C1CC(c2ccc(C[C@H](NS(=O)(=O)c3cccc(C(F)(F)F)c3)c3nc4cc(Cl)ccc4[nH]3)cc2F)S(=O)(=O)[N-]1 CHEMBL377141 IC50 10.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4cccc(Cl)c4)CC3)c2)c1Br CHEMBL390244 Ki 10.0 nM
O=C(O)[C@@H](CCN1C(=O)c2ccccc2C1=O)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br CHEMBL326425 IC50 11.0 nM
COC(=O)c1ccc(C(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)n2nnc3ccccc32)cc1 CHEMBL268903 IC50 11.0 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc3cc(F)c(C(F)(F)P(=O)(O)O)cc3n2)cc1 CHEMBL1938829 IC50 11.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2ccc(F)c(F)c2)n2nnc3ccccc32)cc1 CHEMBL267048 IC50 12.0 nM
Cc1ccc2cc(-c3ccc(CC(Cc4ccc(C(F)(F)P(=O)(O)O)cc4)(c4ccccc4)n4nnc5ccccc54)cc3)cc(P(=O)(O)O)c2n1 CHEMBL268526 IC50 12.0 nM
CCc1cc(CC(NC(C)=O)C(=O)NCCCCOc2cccc(O)c2C(=O)OC)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL116605 pKi 12.59 nM
CS(=O)(=O)OC1C(Cl)CCCC1Cc1ccc(N2CC(=O)CS2(=O)=O)c(O)c1 CHEMBL604457 IC50 12.6 nM
CN(C)S(=O)(=O)c1ccc(CN(Cc2ccc(C(F)(F)P(=O)(O)O)c(Br)c2)S(=O)(=O)c2ccc(OCC(=O)O)cc2)cc1 CHEMBL198940 Ki 13.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(OCC3CCN(C(=O)Nc4ccccc4)CC3)c2)c1Br CHEMBL230543 Ki 13.0 nM
O=P(O)(O)C(F)(F)c1ccc(C[C@](c2ccc(C(F)(F)P(=O)(O)O)cc2)(c2ccc(F)c(F)c2)n2nnc3ccccc32)cc1 CHEMBL5273366 IC50 13.0 nM
CN(Cc1ccccc1)C(=O)CN(Cc1ccc(C(F)(F)P(=O)(O)O)c(Br)c1)S(=O)(=O)c1ccc(OCC(=O)O)cc1 CHEMBL372592 Ki 14.0 nM
CCNC(=O)Nc1ccccc1CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL397903 Ki 14.0 nM
O=C1CN(c2c(O)cc(CC3CCCCC3)cc2F)S(=O)(=O)C1 CHEMBL592290 IC50 14.0 nM
O=C1C[C@@H](c2ccc(C[C@H](NS(=O)(=O)c3cccc(F)c3)c3nc4ccccc4[nH]3)cc2F)S(=O)(=O)[N-]1 CHEMBL381584 IC50 15.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)CN)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)O)C(C)C CHEMBL4782991 Kd 15.1 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL276647 IC50 16.0 nM
O=P(O)(O)C(F)(F)c1ccc(/C=C/CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL274435 IC50 16.0 nM
Cc1cc(C[C@H](NS(=O)(=O)c2ccc(Br)c(C(F)(F)F)c2)c2nc3ccccc3[nH]2)ccc1[C@@H]1CC(=O)[N-]S1(=O)=O CHEMBL378614 IC50 16.0 nM
CC(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(c1ccccc1)n1nnc2ccccc21 CHEMBL410646 IC50 16.0 nM
CCC(CC)c1ccc(N(Cc2cccc(-c3ccc(COc4ccc(C[C@H](NC(C)=O)C(=O)O)cc4)cc3)c2)C(C)C)cc1 CHEMBL590480 IC50 16.0 nM
O=P(O)(O)C(F)(F)c1ccc(C[C@@](c2ccccc2)(c2ccc(C(F)(F)P(=O)(O)O)cc2)n2nnc3ccccc32)cc1 CHEMBL5289453 IC50 16.0 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc3cc(Br)c(C(F)(F)P(=O)(O)O)cc3c2)cc1 CHEMBL1938824 IC50 17.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2nc3ccccc3s2)n2nnc3ccccc32)cc1 CHEMBL8662 IC50 18.0 nM
O=C(O)C(=O)Nc1sc2c(c1C(=O)O)CCNC2CNC(=O)c1cc2cc(F)ccc2[nH]1 CHEMBL185891 Ki 18.0 nM
Cc1cc(C[C@H](NS(=O)(=O)c2ccccc2C#N)c2nc3ccccc3[nH]2)ccc1[C@@H]1CC(=O)[N-]S1(=O)=O CHEMBL211352 IC50 18.0 nM
O=C1CC(c2ccc(C[C@H](NS(=O)(=O)c3ccccc3)c3nc4ccccc4[nH]3)cc2F)S(=O)(=O)[N-]1 CHEMBL208114 IC50 18.0 nM
O=C(O)C(=O)Nc1sc2c(c1C(=O)O)CCN[C@H]2CNC(=O)c1cc2cc(F)ccc2[nH]1 CHEMBL591998 Ki 18.0 nM
CCc1cc(C[C@H](NC(C)=O)C(=O)NCCCCOc2cccc(O)c2C(=O)OC)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL590122 Ki 18.0 nM
CCc1cc(C[C@H]2NC(=O)CN(CCCCOc3cccc(O)c3C(=O)OC)C2=O)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL1241315 Ki 18.0 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc3cc(Br)c(C(F)(F)P(=O)(O)O)cc3n2)cc1 CHEMBL1938825 IC50 18.0 nM
CCc1cc(CN(C(C)=O)C(=O)NCCCCOc2cccc(O)c2C(=O)OC)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL2377808 Ki 18.0 nM
CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(OCC)c(C(=O)OC)c1 CHEMBL4164960 IC50 18.6 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2nc(-c3ccccc3)cs2)n2nnc3ccccc32)cc1 CHEMBL9473 IC50 19.0 nM
CC(=O)N[C@@H](Cc1ccc(N(C(=O)C(=O)O)c2ccccc2C(=O)O)c2ccccc12)C(=O)NCCCCCOc1cc2ccccc2cc1C(=O)O CHEMBL1230341 pKi 19.95 nM
CCCCCNC(=O)[C@H](Cc1ccc(N(C(=O)C(=O)O)c2ccccc2C(=O)O)c(/C=C/C(N)=O)c1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCC(=O)O CHEMBL558555 pKi 19.95 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2ccc3ccccc3n2)n2nnc3ccccc32)cc1 CHEMBL273474 IC50 20.0 nM
CN(CCCCCl)P(=O)(OCc1cc([N+](=O)[O-])co1)C(F)(F)c1ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc2ccc(C(F)(F)P(=O)(OCc3ccc([N+](=O)[O-])o3)N(C)CCCCCl)cc2)C(N)=O)cc1 CHEMBL1765346 IC50 20.0 nM
CC(=O)NC(Cc1ccc(N(C(=O)C(=O)O)c2ccccc2C(=O)O)c2ccccc12)C(=O)NCCCCCOc1cc2ccccc2cc1C(=O)O CHEMBL324968 Ki 22.0 nM
Cc1cc(CC(NS(=O)(=O)c2cccc(F)c2)C2=NC[C@@H](CCCCOc3cccc(O)c3C(=O)O)N2)ccc1C1CC(=O)NS1(=O)=O CHEMBL403468 IC50 22.0 nM
CC(=O)N[C@H](Cc1ccc(N(C(=O)C(=O)O)c2ccccc2C(=O)O)c2ccccc12)C(=O)NCCCCCOc1cc2ccccc2cc1C(=O)O CHEMBL541953 IC50 22.0 nM
CCCCCCC(Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1Br)C(=O)O CHEMBL25189 IC50 23.0 nM
Cc1cc(CC(NS(=O)(=O)c2cccc(F)c2)C2=NC[C@@H](CCOc3cccc(S(C)(=O)=O)c3)N2)ccc1C1CC(=O)NS1(=O)=O CHEMBL253476 IC50 23.0 nM
Cc1cc(CC(NS(=O)(=O)c2cccc(F)c2)C2=N[C@H](CCOc3ccccc3S(C)(=O)=O)CN2)ccc1C1CC(=O)NS1(=O)=O CHEMBL590689 IC50 23.0 nM
O=P(O)(O)C(F)(F)c1ccc(C[C@](/C=C/c2ccccc2)(c2nc3ccccc3s2)n2nnc3ccccc32)cc1 CHEMBL5268825 IC50 23.0 nM
CCc1ccc(C(=O)NCCCCC(NC(=O)C(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)NC(=O)C(Cc2ccccc2)NC(=O)COC2CC(C)CCC2C(C)C)C(N)=O)cc1 CHEMBL3969776 Ki 23.1 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc2Br)cc1O CHEMBL285308 IC50 24.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(OC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br CHEMBL244564 Ki 24.0 nM
NS(=O)(=O)C(F)(F)c1cc(-c2ccc(CSCc3ccc(C(F)(F)P(=O)(O)O)c(Br)c3)cc2)ccc1Br CHEMBL1162226 Ki 24.0 nM
CC(C)C[C@H](NC(=O)[C@@H](Cc1cccc(C(F)(F)P(=O)(O)O)c1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(=O)O)C(N)=O CHEMBL1162228 Ki 24.0 nM
COc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(-c3ccc(OC)cc3)c2OCC(=O)O)cc1 CHEMBL284471 IC50 25.0 nM
COc1cccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(-c3cccc(OC)c3)c2OCC(=O)O)c1 CHEMBL26103 IC50 25.0 nM
O=C(O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br CHEMBL1083714 IC50 25.0 nM
CCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(N)=O CHEMBL3426930 Ki 25.0 nM
O=C(O)c1cc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)oc5ccccc45)cc3)cc2)ccc1O CHEMBL441959 IC50 26.0 nM
CC1(C)CC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC(C)(C)C1 CHEMBL243942 Ki 26.0 nM
CCCCCCCCCCCCCCC(=O)N[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(N)=O)c1ccc(C(F)(F)P(=O)(O)O)cc1 CHEMBL1765345 Ki 26.0 nM
CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(N)=O)[C@@H](C)CC)[C@@H](C)CC CHEMBL4557598 Kd 26.9 nM
O=C(Nc1cccc(F)c1)c1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2n1 CHEMBL261362 IC50 27.0 nM
O=C1C[C@@H](c2ccc(C[C@H](Nc3nc4ccccc4s3)c3nc4ccccc4[nH]3)cc2F)S(=O)(=O)N1 CHEMBL607027 IC50 27.0 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)oc5ccccc45)cc3)cc2C2CCCC2)cc1O CHEMBL24331 IC50 28.0 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc2)cc1O CHEMBL25368 IC50 28.0 nM
COc1cccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(Br)c2OCC(=O)O)c1 CHEMBL25628 IC50 28.0 nM
COc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(Br)c2OCC(=O)O)cc1 CHEMBL278092 pIC50 28.84 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)oc5ccccc45)cc3)cc2[N+](=O)[O-])cc1O CHEMBL538903 IC50 29.0 nM
O=C(O)c1ccc(S(=O)(=O)Oc2c(Br)cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc2Br)cc1O CHEMBL285307 IC50 30.0 nM
NS(=O)(=O)C(F)(F)c1ccc(CN(Cc2ccc(-c3csnn3)cc2)S(=O)(=O)c2ccc(OCC(=O)O)cc2)cc1F CHEMBL1938819 IC50 31.0 nM
CCc1cc(CC(NC(C)=O)C(=O)NCCCCOc2cccc(O)c2C(=O)O)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL117699 pKi 31.62 nM
Cc1sc(Cc2ccccc2)c(-c2ccc(-c3ccc(OS(=O)(=O)c4ccc(C(=O)O)c(O)c4)cc3)cc2)c1C CHEMBL24566 IC50 32.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2nnn[nH]2)n2nnc3ccccc32)cc1 CHEMBL418703 IC50 32.0 nM
O=C1C[C@@H](c2ccc(C[C@H](NS(=O)(=O)c3ccccc3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)[N-]1 CHEMBL210836 IC50 32.0 nM
Cc1cc(CC(NS(=O)(=O)c2cccc(F)c2)c2ncc(CCCCOc3cccc(O)c3C(=O)O)[nH]2)ccc1C1CC(=O)NS1(=O)=O CHEMBL402032 IC50 32.0 nM
Cc1cc(C[C@H](NS(=O)(=O)c2ccccc2)c2nc3ccccc3[nH]2)ccc1[C@@H]1CC(=O)NS1(=O)=O CHEMBL248291 IC50 32.0 nM
Cc1cc(C[C@H](NS(=O)(=O)c2ccccc2)c2nc3ccccc3[nH]2)ccc1N1CC(=O)NS1(=O)=O CHEMBL592245 IC50 32.0 nM
O=P(O)(Cc1cc2c(O)c(c1)S(=O)(=O)c1cc(CP(=O)(O)c3ccccc3)cc(c1O)S(=O)(=O)c1cc(CP(=O)(O)c3ccccc3)cc(c1O)S(=O)(=O)c1cc(CP(=O)(O)c3ccccc3)cc(c1O)S2(=O)=O)c1ccccc1 CHEMBL4569405 Ki 32.0 nM
Cc1cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc(C)c1OS(=O)(=O)c1ccc(C(=O)O)c(O)c1 CHEMBL24524 IC50 34.0 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc(C(F)(F)P(=O)(O)O)c(Br)c2)cc1 CHEMBL371929 IC50 35.0 nM
Cc1cc(C[C@H](NS(=O)(=O)c2ccccc2)c2nc3ccccc3[nH]2)ccc1[C@@H]1CC(=O)[N-]S1(=O)=O CHEMBL377989 IC50 35.0 nM
CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc([C@@H]2CC(=O)NS2(=O)=O)cc1)c1nc2ccccc2[nH]1 CHEMBL211655 IC50 35.0 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc(C(F)(F)P(=O)(O)O)c(F)c2)cc1 CHEMBL1938816 IC50 35.0 nM
NS(=O)(=O)C(F)(F)c1cc2cc(CN(Cc3ccc(-c4csnn4)cc3)S(=O)(=O)c3ccc(OCC(=O)O)cc3)ccc2cc1F CHEMBL1938830 IC50 35.0 nM
O=C(O)[C@H](Cc1ccccc1)Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1Br CHEMBL1086226 IC50 38.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(-c3ccccc3)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL267759 IC50 38.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccc(Cl)cc4)CC3)c2)c1Br CHEMBL230643 Ki 38.0 nM
NS(=O)(=O)C(F)(F)c1cc2nc(CN(Cc3ccc(-c4csnn4)cc3)S(=O)(=O)c3ccc(OCC(=O)O)cc3)ccc2cc1F CHEMBL1938831 IC50 38.0 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)oc5ccccc45)cc3)cc2)cc1O CHEMBL23998 IC50 39.0 nM
NS(=O)(=O)C(F)(F)c1cc2cc(CN(Cc3ccc(-c4csnn4)cc3)S(=O)(=O)c3ccc(OCC(=O)O)cc3)ccc2cc1Br CHEMBL1938826 IC50 39.0 nM
COC(=O)c1ccc(C(C/C=C/c2ccccc2)(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)n2nnc3ccccc32)cc1 CHEMBL3817887 IC50 39.0 nM
CCc1cc(CC(NC(C)=O)C(=O)NCCCCOc2cc(Cl)cc(O)c2C(=O)OC)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL117496 pKi 39.81 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(C(=O)c5ccccc5)oc5ccccc45)cc3)cc2C2CCCC2)cc1O CHEMBL24481 IC50 40.0 nM
O=C(OCc1ccccc1)C(Cc1ccc(C(F)(F)C(=O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)OCc1ccccc1 CHEMBL9046 IC50 40.0 nM
CCCCCNC(=O)[C@H](Cc1ccc([C@@H]2CC(=O)NS2(=O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc(OC)cc1 CHEMBL1765347 IC50 40.0 nM
COC(=O)C(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)OCc1ccccc1 CHEMBL8725 IC50 40.0 nM
CC(C)OC(=O)C(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)OC(C)C CHEMBL8767 IC50 40.0 nM
O=C(OCc1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)OCc1ccccc1 CHEMBL267954 IC50 40.0 nM
O=C(Cc1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)Cc1ccccc1 CHEMBL5271227 IC50 40.0 nM
NS(=O)(=O)C(F)(F)c1cc2nc(CN(Cc3ccc(-c4csnn4)cc3)S(=O)(=O)c3ccc(OCC(=O)O)cc3)ccc2cc1Br CHEMBL1938827 IC50 41.0 nM
COc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)oc5ccccc45)cc3)ccc2O[C@@H](Cc2ccccc2)C(=O)O)cc1 CHEMBL1086227 pIC50 42.66 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(F)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL424880 IC50 43.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(F)c3)c3ncc(CCCc4ccccc4)[nH]3)cc2)S(=O)(=O)N1 CHEMBL253500 IC50 43.0 nM
O=C(O)C(CCN1C(=O)c2ccccc2C1=O)Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br CHEMBL25486 IC50 44.0 nM
CS(=O)(=O)N1CCC(Nc2cccc(-c3sc(C(=O)O)c(OCC(=O)O)c3Br)c2)CC1 CHEMBL244148 Ki 44.0 nM
N#Cc1ccccc1S(=O)(=O)NC(Cc1ccc(C2CC(=O)NS2(=O)=O)cc1)c1nc2ccccc2[nH]1 CHEMBL212260 IC50 45.0 nM
O=C(NCc1ccccc1)c1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2n1 CHEMBL261108 IC50 45.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(CCCc2ccccc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL9321 IC50 46.0 nM
COc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(Br)c2OCC(=O)O)c(OC)c1 CHEMBL24607 pIC50 46.77 nM
NS(=O)(=O)C(F)(F)c1ccc(CN(Cc2ccc(-c3csnn3)cc2)S(=O)(=O)c2ccc(OCC(=O)O)cc2)cc1Br CHEMBL1938818 IC50 47.0 nM
COc1cccc(S(=O)(=O)NC(Cc2ccc(C3CC(=O)NS3(=O)=O)cc2)c2nc3ccccc3[nH]2)c1 CHEMBL377735 IC50 48.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(C/C=C/c2ccccc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL416145 IC50 49.0 nM
O=C1C[C@@H](c2ccc(C[C@H](NS(=O)(=O)c3ccccc3)c3nc4ccccc4[nH]3)cc2Cl)S(=O)(=O)[N-]1 CHEMBL208604 IC50 50.0 nM
COC(=O)CN(c1ccc(CN(c2ccc(OCc3ccc(C)cc3)c(C(=O)OC)c2)S(=O)(=O)Cc2ccccc2)cc1)S(C)(=O)=O CHEMBL3822604 IC50 50.0 nM
CC(C)C(NC1=NS(=O)(=O)c2ccccc21)C(=O)NCC(NC(=O)c1n[nH]c2ccc([N+](=O)[O-])cc12)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC21)C(N)=O CHEMBL4796866 Kd 50.0 nM
CC(C)C(NC1=NS(=O)(=O)c2ccccc21)C(=O)NCC(NC(=O)c1n[nH]c2ccc([N+](=O)[O-])cc12)C(N)=O CHEMBL4786214 Kd 50.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL206950 IC50 51.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccc(C(F)(F)F)cc3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL207489 IC50 51.0 nM
O=C(CCCC[C@@H]1CCSS1)Nc1ccc2c(c1)CO[C@H](C(=O)O)C2 CHEMBL564124 IC50 51.63 nM
CCOc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)ccc2OCC(=O)O)cc1 CHEMBL284765 IC50 52.0 nM
CCCCC(Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1Br)C(=O)O CHEMBL26399 IC50 52.0 nM
O=C(O)[C@@H](Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1-c1ccc(Cl)cc1 CHEMBL1082298 IC50 52.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(C(F)(F)F)c3)c3ncc(CCCc4ccccc4)[nH]3)cc2)S(=O)(=O)N1 CHEMBL253269 IC50 52.0 nM
COc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)ccc2O[C@H](Cc2ccccc2)C(=O)O)cc1 CHEMBL1082297 pIC50 52.48 nM
N#Cc1ccc2[nH]c(C(Cc3ccc(C4CC(=O)NS4(=O)=O)cc3)NS(=O)(=O)c3ccc(-c4ccccc4)cc3)nc2c1 CHEMBL264833 IC50 53.0 nM
CC(C)C[C@@H](Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1Br)C(=O)O CHEMBL1084870 pIC50 53.7 nM
COC(=O)C(CCNC(=O)c1ccccc1C(=O)O)Oc1c(Br)cc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br CHEMBL25594 IC50 54.0 nM
O=C(O)[C@H](Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1C1CCCC1 CHEMBL1086230 pIC50 54.95 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)c4ccccc4)CC3)c2)c1Br CHEMBL244360 Ki 55.0 nM
O=C(O)[C@H](Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1Br CHEMBL366281 IC50 56.0 nM
O=C(O)COc1ccc(S(=O)(=O)N(Cc2ccc(-c3csnn3)cc2)Cc2ccc(C(F)(F)P(=O)(O)O)cc2)cc1 CHEMBL198882 Ki 56.0 nM
O=C(O)[C@@H](Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br CHEMBL187610 pIC50 57.54 nM
COc1cc(CN(Cc2ccc(-c3csnn3)cc2)S(=O)(=O)c2ccc(OCC(=O)O)cc2)ccc1C(F)(F)P(=O)(O)O CHEMBL198939 IC50 60.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(Cl)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL212147 IC50 60.0 nM
O=C(Nc1ccccc1)c1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2n1 CHEMBL261418 IC50 60.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@@H](N)[C@@H](C)O)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)CC)[C@@H](C)CC CHEMBL4789031 Kd 60.7 nM
O=C(O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br CHEMBL290496 IC50 61.0 nM
N#Cc1ccc(S(=O)(=O)NC(Cc2ccc(C3CC(=O)NS3(=O)=O)cc2)c2nc3ccccc3[nH]2)cc1 CHEMBL383437 IC50 63.0 nM
CCc1cc(CC(NC(C)=O)C(=O)NCCCCC(=O)N[C@@H](CCSC)C(=O)O)ccc1N(C(=O)C(=O)O)c1cc(Cl)ccc1C(=O)O CHEMBL564753 pKi 63.1 nM
CCc1cc(CC(NC(C)=O)C(=O)NCCCCC(=O)N[C@@H](CCSC)C(=O)O)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL55243 pKi 63.1 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(F)c3)C3=NC[C@@H](Cc4ccccc4F)N3)cc2)S(=O)(=O)N1 CHEMBL428589 IC50 64.0 nM
O=C1C[C@@H](c2ccc(C[C@H](NS(=O)(=O)c3cccc(F)c3)c3nc(Cc4ccccc4F)c[nH]3)cc2)S(=O)(=O)N1 CHEMBL3747361 IC50 64.0 nM
CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(OCC)c(C(=O)Nc2ccc(OC)c(OC)c2)c1 CHEMBL4175748 IC50 66.2 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(C(F)(F)F)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL436933 IC50 67.0 nM
CCCOc1ccc(NC(=O)NCc2cc(OCC)c(NS(C)(=O)=O)cc2OCC)cc1C(=O)OC CHEMBL4172149 IC50 68.2 nM
NS(=O)(=O)c1ccccc1-c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL9252 IC50 69.0 nM
CCc1csc([C@H](Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)[C@H](CC(C)C)C(=O)OC)n1 CHEMBL590155 IC50 70.0 nM
O=C(O)C(Cc1c[nH]c2ccccc12)N1C(=O)/C(=C/c2ccc3cc(OCc4ccc(Br)cc4)ccc3c2)SC1=S CHEMBL4475724 Ki 70.0 nM
CCOS(=O)(=O)/C=C/c1ccc(COc2cc(COc3ccc(C(=O)O)c(O)c3)ccc2C(=O)Nc2ccc(Oc3ccc(-c4ccccc4)cc3)cc2)cc1 CHEMBL4636119 IC50 70.0 nM
COc1cccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)ccc2OCC(=O)O)c1OC CHEMBL429385 pIC50 70.79 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cc(F)cc(F)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL210324 IC50 72.0 nM
O=C(O)/C=C/c1ccc(-c2nc(-c3ccc(C(=O)O)cc3)[nH]c2-c2ccc(/C=C/C(=O)O)cc2)cc1 CHEMBL5281085 IC50 72.0 nM
Cc1oc2cc3sc4ccccc4c3c(-c3cc(I)c(O[C@H](Cc4ccccc4)C(=O)O)c(I)c3)c2c1C CHEMBL39626 IC50 74.0 nM
Cc1cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc(C)c1O[C@H](Cc1ccccc1)C(=O)O CHEMBL1086229 IC50 74.0 nM
O=P(O)(O)C(F)(F)c1ccc(C(c2ccc(-c3ccccc3-c3nn[nH]n3)cc2)C(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL276648 IC50 74.0 nM
O=C(O)COc1c(C(=O)O)sc(-c2cccc(NCC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br CHEMBL388426 Ki 74.0 nM
O=C(O)c1ccc(S(=O)(=O)Oc2ccc(-c3ccc(-c4c(Cc5ccccc5)oc5ccccc45)cc3)cc2)cc1 CHEMBL276983 IC50 75.0 nM
Cc1cc(C[C@H](NS(=O)(=O)c2cccc(Cl)c2)c2nc3ccccc3[nH]2)ccc1[C@@H]1CC(=O)[N-]S1(=O)=O CHEMBL377441 IC50 76.0 nM
CCc1cc(CC(NC(C)=O)C(=O)NCCCCC(=O)NC(CCSC)C(=O)O)ccc1N(C(=O)C(=O)O)c1ccccc1C(=O)O CHEMBL3818765 Ki 76.0 nM
COc1ccc(Cc2sc3ccccc3c2-c2ccc(-c3ccc(O[C@H](Cc4ccccc4)C(=O)O)cc3)cc2)cc1 CHEMBL1083272 IC50 77.0 nM
CC1(C)Oc2ccc(Cc3sc4ccccc4c3-c3ccc(-c4ccc(O[C@H](Cc5ccccc5)C(=O)O)cc4)cc3)cc2O1 CHEMBL3350938 IC50 77.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(Br)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL209107 IC50 77.0 nM
CC[C@H](C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)O)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)CC CHEMBL4748920 Kd 77.8 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL210965 IC50 79.0 nM
COc1ccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)ccc2OCC(=O)O)cc1 CHEMBL24843 pIC50 79.43 nM
O=C(O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(Br)c3oc4ccccc4c23)cc1Br CHEMBL324232 IC50 80.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccc(-c4ccccc4)cc3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL211033 IC50 80.0 nM
Cc1ccc(S(=O)(=O)NC(Cc2ccc(C3CC(=O)NS3(=O)=O)cc2)c2nc3ccccc3[nH]2)cc1 CHEMBL208985 IC50 80.0 nM
O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccc(F)cc3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 CHEMBL380164 IC50 80.0 nM
O=C(CCCC[C@@H]1CCSS1)Nc1ccc2c(c1)C[C@@H](C(=O)O)OC2 CHEMBL562469 IC50 80.0 nM
O=C1CN(c2cc(-c3ccc[nH]3)ccc2O)S(=O)(=O)N1 CHEMBL601290 IC50 80.0 nM
O=C1CN(c2c(O)cc(CC3CCCCC3)cc2F)S(=O)(=O)N1 CHEMBL5268430 IC50 80.0 nM
CS(=O)(=O)Oc1c(Cl)cccc1Cc1ccc(N2CC(=O)NS2(=O)=O)c(O)c1 CHEMBL5267772 IC50 80.0 nM
O=C1CN(c2ccc(-c3ccc[nH]3)cc2O)S(=O)(=O)N1 CHEMBL5265859 IC50 80.0 nM
COc1ccc2cc(O)c(N3CC(=O)NS3(=O)=O)cc2c1 CHEMBL1208413 IC50 80.0 nM
O=C(O)CNc1cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)ccc1OCCc1ccccc1 CHEMBL284763 pIC50 81.28 nM
O=C(O)c1cccc2c1oc1ccc(-c3csc(-c4ccc(N5CCCC5)cc4)n3)cc12 CHEMBL1242362 IC50 82.0 nM
COc1ccc(Cc2sc3ccccc3c2-c2ccc(-c3ccc(O[C@H](Cc4ccccc4)C(=O)O)cc3)cc2)c(OC)c1 CHEMBL190535 IC50 85.0 nM
Cc1cccc(S(=O)(=O)NC(Cc2ccc(C3CC(=O)NS3(=O)=O)cc2)c2nc3ccccc3[nH]2)c1 CHEMBL211076 IC50 85.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)O CHEMBL4789297 Kd 86.3 nM
CCc1ccc(C(=O)NCCCCC(NC(=O)C(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)NC(=O)C(Cc2ccccc2)NC(C)=O)C(N)=O)cc1 CHEMBL3942718 IC50 87.0 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(Br)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL9339 IC50 89.0 nM
CC(=O)NS(=O)(=O)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(C(=O)OCc2ccccc2)C(=O)OCc2ccccc2)cc1 CHEMBL263348 IC50 90.0 nM
N#CCc1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2c1 CHEMBL259051 IC50 90.0 nM
CCCCC(NC1=NS(=O)(=O)c2ccccc21)C(=O)NC[C@@H](NC(=O)C1CCCC(NC(=O)[C@H](CC(C)(C)C)n2cc(CC3CCCCC3)nn2)C1)C(=O)NC(CCCCNC(=O)CCCC[C@@H]1SCC2NC(=O)NC21)C(N)=O CHEMBL4752726 Kd 90.0 nM
CCCCC(NC1=NS(=O)(=O)c2ccccc21)C(=O)NC[C@@H](NC(=O)C1CCCC(NC(=O)[C@H](CC(C)(C)C)n2cc(CC3CCCCC3)nn2)C1)C(N)=O CHEMBL4754600 Kd 90.0 nM
CCCCCCCCc1ccc(-n2c(C)ccc2-c2ccc(O[C@@H](Cc3ccccc3)C(=O)O)cc2)cc1 CHEMBL5282419 IC50 90.0 nM
COc1ccc(S(=O)(=O)NC(Cc2ccc(C3CC(=O)NS3(=O)=O)cc2)c2nc3ccccc3[nH]2)cc1 CHEMBL211171 IC50 94.0 nM
O=C(O)[C@@H](Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1 CHEMBL1084871 IC50 95.0 nM
O=C(CCCCC1CCSS1)Nc1ccc2c(c1)CO[C@H](C(=O)O)C2 CHEMBL556914 IC50 95.67 nM
O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(OCc3ccccc3)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 CHEMBL9374 IC50 98.0 nM
O=P(O)(O)C(F)(F)c1ccc(CN(Cc2ccc(-c3csnn3)cc2)S(=O)(=O)c2ccccc2)cc1 CHEMBL369943 Ki 98.0 nM