C[C@@H]1OCC2(CCN(c3cnc(Sc4cccc(N)c4Cl)c(N)n3)CC2)[C@@H]1N CHEMBL4858291 IC50 0.017 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)c(CO)nc1-c1cccc(Cl)c1Cl CHEMBL4752026 IC50 0.0583 nM
CC1(N)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL4060033 IC50 0.145 nM
C[C@@H]1OCC2(CCN(c3cnc(Sc4cccc(NC(=O)CCC(=O)NCCCOCCOCCOCCCNc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)c4Cl)c(N)n3)CC2)[C@@H]1N CHEMBL4871539 IC50 0.202 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5cccc(Cl)c5Cl)c4nc3CO)CC2)[C@@H]1N CHEMBL5183738 IC50 0.4 nM
Cc1nc(N2CCC3(CC2)OC[C@@H](C)[C@H]3N)c(CO)nc1-c1cccc(Cl)c1Cl CHEMBL5287751 IC50 0.583 nM
N[C@@H]1c2ccccc2CC12CCN(c1nc3nc(Sc4cccnc4C(F)(F)F)cnc3[nH]1)CC2 CHEMBL5276842 Kd 0.6 nM
Cc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)cc(=O)n1-c1cccc(Cl)c1Cl CHEMBL4757590 IC50 0.8 nM
Nc1nc(N2CCC3(CCC[C@H]3N)CC2)cnc1Sc1cccc(NC(=O)c2c(O)nc3n(c2=O)CCCC3)c1Cl CHEMBL4752245 IC50 1.0 nM
Cc1c(N2CCC3(CC2)Cc2ccccc2[C@H]3N)nc(C)n(-c2cccc(Cl)c2Cl)c1=O CHEMBL4797428 IC50 1.0 nM
Cc1c(N2CCC3(CC2)Cc2ncccc2[C@@H]3N)nc(C)n(-c2cccc(Cl)c2Cl)c1=O CHEMBL4794480 IC50 1.0 nM
Cc1nc(N2CCC3(CC2)Cc2nc(O)ccc2[C@H]3N)c2ccnn2c1-c1cccc(F)c1F CHEMBL5412259 IC50 1.0 nM
Cc1c(N2CCC3(CC2)Oc2ccccc2[C@H]3N)nc(C)n(-c2cccc(Cl)c2Cl)c1=O CHEMBL4750774 IC50 1.4 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(=O)(O)O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O CHEMBL5072349 Kd 1.6 nM
Cc1c(F)ccc(-n2c(C)nc(N3CCC4(CC3)Cc3ccccc3[C@H]4N)c(C)c2=O)c1Cl CHEMBL4764184 IC50 2.0 nM
Cc1c(N2CCC3(CC2)Cc2ccccc2[C@H]3N)nc(C)n(-c2ccc(F)c(Cl)c2Cl)c1=O CHEMBL4748666 IC50 2.0 nM
CCCNc1nccc(-c2n[nH]c3nc(N4CCC5(CC4)CO[C@@H](C)[C@H]5N)c(CO)nc23)c1Cl CHEMBL5176625 IC50 2.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4cnc5c(-c6ccc7nc(C)sc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5267582 IC50 2.0 nM
Cc1ccc(-c2c(C)nc(N3CCC4(CC3)Cc3ncccc3[C@H]4N)c3ccnn23)c(F)c1 CHEMBL5402623 IC50 2.0 nM
Cc1nc(N2CCC3(CC2)Cc2ncccc2[C@H]3N)c2ccnn2c1-c1cccc(Cl)c1Cl CHEMBL5402432 IC50 2.0 nM
N[C@@H]1COCC12CCN(c1cnc3c(Sc4cccc(Cl)c4Cl)n[nH]c3n1)CC2 CHEMBL5204926 IC50 2.1 nM
Cc1c(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)nc(C)n(-c2ccc(Oc3ccn(C)n3)c(Cl)c2Cl)c1=O CHEMBL4798989 IC50 3.0 nM
N[C@H]1C[C@@H]2CC[C@H]([C@H]1F)N2c1nc2[nH]nc(-c3ccc4ncsc4c3Cl)c2nc1CO CHEMBL4741490 IC50 3.0 nM
Nc1nc(N2CCC3(CC2)Cc2cnccc2[C@H]3N)cnc1Sc1ccnc(N)c1Cl CHEMBL4752599 IC50 3.0 nM
N[C@@H]1c2ccccc2CC12CCN(c1nc3nc(Sc4ccncc4Cl)cnc3[nH]1)CC2 CHEMBL5288562 IC50 3.0 nM
Cc1csc([C@]2(CN)[C@@H]3CCN(c4cnc5c(-c6cccc(Cl)c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5281311 IC50 3.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4cnc5c(-c6ccn7nccc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5282278 IC50 3.0 nM
CC1(N)CCN(c2cnc3c(Sc4ccnc(N)c4Cl)n[nH]c3n2)CC1 CHEMBL5430267 IC50 3.0 nM
N[C@@H]1Cc2ccccc2C12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5439718 IC50 3.0 nM
Cc1nc(N2CCC3(CC2)Cc2ncccc2[C@H]3N)c2ccnn2c1-c1ccc2c(c1)OCCO2 CHEMBL5397998 IC50 3.0 nM
Cc1nc(N2CCC3(CC2)Cc2ncccc2[C@H]3N)c2ccnn2c1-c1ccc(F)cc1F CHEMBL5411170 IC50 3.0 nM
Cc1nc(N2CCC3(CC2)Cc2ncccc2[C@H]3N)c2ccnn2c1-c1ccc(F)c2cc[nH]c12 CHEMBL5423545 IC50 3.0 nM
CN(C)C(=O)c1cc2cnc(Nc3nccc(Sc4cnc(N5CCC6(CC5)Cc5ccccc5[C@H]6N)cn4)c3Cl)nc2n1C1CCCC1 CHEMBL5171286 IC50 3.2 nM
C[C@@H]1OCC2(CCN(c3cnc(Sc4ccnc(N)c4Cl)c(N)n3)CC2)[C@@H]1N CHEMBL4650521 IC50 3.8 nM
C[C@H]1C[C@@H](N)C2(CCN(c3nc(N)c(Sc4cccnc4C(F)(F)F)c(=O)n3C)CC2)C1 CHEMBL4581388 IC50 4.0 nM
Nc1nc(N2CCC3(CC2)Cc2ccccc2[C@H]3N)cnc1Sc1ccnc(N)c1Cl CHEMBL4789817 IC50 4.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(=O)(O)O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O CHEMBL5085273 Kd 4.0 nM
Nc1nccc(Sc2cnc3[nH]c(N4CCC5(CC4)Cc4ccccc4[C@H]5N)nc3n2)c1Cl CHEMBL5274747 IC50 4.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccn7nccc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5291336 IC50 4.0 nM
Cc1cccc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5271919 IC50 4.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5cnsn5)cnc34)ccc2n1 CHEMBL5268577 IC50 4.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5nccs5)cnc34)ccc2n1 CHEMBL5289856 IC50 4.0 nM
CS(=O)(=O)c1cccc2c1CCCN2c1n[nH]c2nc(N3CCC4(CC3)Cc3ccccc3[C@H]4N)cnc12 CHEMBL5438708 IC90 4.0 nM
N[C@@H]1c2ccccc2OC12CCN(c1nc3[nH]nc(N4CCCc5ncccc54)c3nc1CO)CC2 CHEMBL5429179 IC90 4.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4nccc(Sc5cnc(N6CCC7(CC6)CO[C@@H](C)[C@H]7N)cn5)c4Cl)ncc3F)cc2n1C(C)C CHEMBL5179617 IC50 4.3 nM
CC1(NCC(=O)NCc2ccc(/C=C/C(=O)NO)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5198194 IC50 4.5 nM
C[C@@H]1CC2(CCN(c3nc(N)c(Sc4cccnc4C(F)(F)F)c(=O)n3C)CC2)[C@H](N)[C@H]1F CHEMBL4537504 IC50 5.0 nM
C[C@@H]1OCC2(CCN(c3nc(N)c(Sc4cccc(Cl)c4Cl)c(=O)n3C)CC2)[C@@H]1N CHEMBL4546378 IC50 5.0 nM
C[C@@H]1OCC2(CCN(c3cnc4c(-c5cccc(Cl)c5Cl)n[nH]c4n3)CC2)[C@@H]1N CHEMBL4475043 IC50 5.0 nM
NC[C@]1(c2ccccn2)[C@@H]2CCN(c3cnc4c(-c5cccc(Cl)c5Cl)n[nH]c4n3)C[C@@H]21 CHEMBL5270277 IC50 5.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nc(C)sc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5275370 IC50 5.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5290261 IC50 5.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5ccccn5)cnc34)ccc2n1 CHEMBL5273026 IC50 5.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5nc(Cl)cs5)cnc34)ccc2n1 CHEMBL5272403 IC50 5.0 nM
C[C@@H]1OCC2(CCN(c3cnc4c(N5CCCc6ncccc65)n[nH]c4n3)CC2)[C@@H]1N CHEMBL5433575 IC50 5.0 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5cccc(Cl)c5F)c4nc3CO)CC2)[C@@H]1N CHEMBL4782469 IC50 5.4 nM
CC1(NCC(=O)Nc2ccc(/C=C/C(=O)NO)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5175565 IC50 5.6 nM
N[C@@H]1CCCC12CCN(c1cnc3c(-c4cccc(Cl)c4Cl)n[nH]c3n1)CC2 CHEMBL5192885 IC50 6.0 nM
CNc1nccc(Sc2cnc3[nH]c(N4CCC5(CC4)Cc4ccccc4[C@H]5N)nc3n2)c1Cl CHEMBL5278011 IC50 6.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4cnc5c(-c6cccc(Cl)c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5290513 IC50 6.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5278658 IC50 6.0 nM
Cc1nc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)cs1 CHEMBL5270851 IC50 6.0 nM
CN1Cc2c(ccc3c2CCCN3c2n[nH]c3nc(N4CCC5(CC4)Cc4ccccc4[C@H]5N)cnc23)C1=O CHEMBL5406138 IC90 6.0 nM
Nc1nc(N2CCC3(CC2)Cc2ccncc2[C@H]3N)cnc1Sc1ccnc(N)c1Cl CHEMBL4752704 IC50 7.0 nM
Nc1nc(N2CCC3(CC2)COC[C@H]3N)cnc1Sc1ccnc(N)c1Cl CHEMBL4740294 IC50 7.0 nM
Cn1nc2ccc(-c3n[nH]c4nc(N5CCC6(CC5)CC(F)(F)C[C@H]6N)c(CO)nc34)c(Cl)c2c1Cl CHEMBL4762585 IC50 7.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(=O)(O)O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O CHEMBL5082085 Kd 7.0 nM
Cn1ccc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5278669 IC50 7.0 nM
N[C@@H]1c2cc(F)ccc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5417946 IC90 7.0 nM
C[C@@H](O)c1nc2c(N3CCCc4ncccc43)n[nH]c2nc1N1CCC2(CC1)Oc1ccccc1[C@H]2N CHEMBL5428394 IC90 7.0 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccc6nn(C)c(Cl)c6c5Cl)c4nc3CO)CC2)[C@@H]1N CHEMBL4759997 IC50 7.1 nM
Cn1nc2ccc(-c3n[nH]c4nc(N5CCC6(CC5)C[C@H](F)C[C@H]6N)c(CO)nc34)c(Cl)c2c1Cl CHEMBL4788960 IC50 7.1 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccncc5)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4452417 IC50 8.0 nM
Nc1nc(N2CCC3(CC2)c2ccccc2C[C@H]3N)cnc1Sc1ccnc(N)c1Cl CHEMBL4761760 IC50 8.0 nM
N[C@@H]1CCCC12CCN(c1nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]1)CC2 CHEMBL5180399 IC50 8.0 nM
NC[C@]1(c2ccsc2)[C@@H]2CCN(c3cnc4c(-c5cccc(Cl)c5Cl)n[nH]c4n3)C[C@@H]21 CHEMBL5275479 IC50 8.0 nM
N[C@@H]1c2ccc(F)cc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5418492 IC90 8.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4nccc(Sc5cnc(N6CCC7(CC6)Cc6ccccc6[C@H]7N)cn5)c4Cl)ncc3F)cc2n1C(C)C CHEMBL5194505 IC50 8.2 nM
Nc1nc(N2CCC3(CC2)CC2CC2C3N)cnc1Sc1ccnc(N)c1Cl CHEMBL4792498 IC50 8.3 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4nc5nc(Sc6cccnc6C(F)(F)F)cnc5[nH]4)C[C@@H]32)n1 CHEMBL5269824 IC50 9.0 nM
NC[C@]1(c2ccccc2)[C@@H]2CCN(c3cnc4c(-c5cccc(Cl)c5Cl)n[nH]c4n3)C[C@@H]21 CHEMBL5290180 IC50 9.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5ccccc5)cnc34)ccc2n1 CHEMBL5283063 IC50 9.0 nM
CCOc1cc(O)c(C(=O)/C=C/c2ccc(Cl)cc2Cl)cc1CN1CCC=C(C2C(=O)Nc3ccccc32)C1 CHEMBL5268100 IC50 9.8 nM
C[C@@H]1OCC2(CCN(c3nc(N)c(Sc4ccnc(C5CC5)c4Cl)c(=O)n3C)CC2)[C@@H]1N CHEMBL4578698 IC50 10.0 nM
Nc1nc(N2CCC3(CCC[C@H]3N)CC2)cnc1Sc1cccc(Cl)c1Cl CHEMBL4800137 IC50 10.0 nM
Nc1nccc(Sc2cnc(N3CCC4(CCC[C@H]4N)CC3)cn2)c1Cl CHEMBL4763213 IC50 10.0 nM
Cc1nnc([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)s1 CHEMBL5275866 IC50 10.0 nM
CC1(N)CCN(c2cnc3c(Oc4ccnc(N)c4Cl)n[nH]c3n2)CC1 CHEMBL5403586 IC50 10.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5CCC6(CC5)CC(F)(F)C[C@H]6N)c(CO)nc34)ccc2n1 CHEMBL4777771 IC50 11.0 nM
COc1cnc2ccc(-c3n[nH]c4nc(N5CCC6(CC5)CO[C@@H](C)[C@H]6N)c(CO)nc34)c(Cl)c2n1 CHEMBL4752044 IC50 11.0 nM
CC1(N)CCN(c2cnc3c(-c4cccc(Cl)c4Cl)n[nH]c3n2)CC1 CHEMBL5191319 IC50 11.0 nM
Cn1c(N2CCC(C)(CN)CC2)nc(N)c(Sc2cccc(Cl)c2Cl)c1=O CHEMBL4533113 IC50 12.0 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5cccc(Cl)c5Cl)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4455446 IC50 12.0 nM
Nc1nc(N2CCC3(CCC[C@H]3N)CC2)cnc1Sc1cccnc1C(F)(F)F CHEMBL4755819 IC50 12.0 nM
N[C@@H]1COCC12CCN(c1cnc3c(-c4cccc(Cl)c4Cl)n[nH]c3n1)CC2 CHEMBL5191221 IC50 12.0 nM
Cn1cc2c(Cl)c(-c3n[nH]c4nc(N5C[C@@H]6[C@H](C5)[C@@]6(CN)c5nc(C(F)(F)F)cs5)cnc34)ccc2n1 CHEMBL5285837 IC50 12.0 nM
CN1c2ccccc2[C@@H](N)C12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5404572 IC50 13.0 nM
N[C@@H]1c2ccccc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5414274 IC90 13.0 nM
N#Cc1ccc2c(c1)[C@@H](N)C1(CCN(c3cnc4c(N5CCCc6ncccc65)n[nH]c4n3)CC1)C2 CHEMBL5438765 IC90 13.0 nM
Nc1nc(N2CCC3(CCC[C@H]3N)CC2)cnc1Sc1ccnc(N)c1Cl CHEMBL4747789 IC50 14.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(C(F)(F)P(=O)(O)O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O CHEMBL5083503 Kd 15.0 nM
Cc1nc2c(N3CCCc4ncccc43)n[nH]c2nc1N1CCC2(CC1)Oc1ccccc1[C@H]2N CHEMBL5411551 IC90 15.0 nM
Cn1cc(-c2ccc3c(n2)CCCN3c2n[nH]c3nc(N4CCC5(CC4)Cc4ccccc4[C@H]5N)cnc23)cn1 CHEMBL5397499 IC90 16.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4cccc(Sc5cnc(N6CCC7(CC6)CO[C@@H](C)[C@H]7N)cn5)c4Cl)ncc3F)cc2n1C(C)C CHEMBL5200081 IC50 16.5 nM
CC1(CN)CCN(c2cnc(Sc3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL4789106 IC50 17.0 nM
C[C@H]1OCC2(CCN(c3cnc(Sc4ccnc(N)c4Cl)c(N)n3)CC2)[C@@H]1N CHEMBL4743002 IC50 17.0 nM
CCNc1nccc(-c2n[nH]c3nc(N4CCC5(CC4)CO[C@@H](C)[C@H]5N)cnc23)c1Cl CHEMBL5183827 IC50 17.0 nM
NC[C@]1(c2ccccn2)[C@@H]2CCN(c3nc4nc(Sc5cccnc5C(F)(F)F)cnc4[nH]3)C[C@@H]21 CHEMBL5271480 IC50 17.0 nM
N[C@@H]1c2cccc(F)c2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5423531 IC90 17.0 nM
CC1(NCc2ccc(/C=C/C(=O)NO)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5174636 IC50 17.2 nM
COc1cc(/N=C(\N)N2CCN(c3cnc(-c4cccc(Cl)c4Cl)c(N)n3)CC2)ccc1C#N CHEMBL5428525 IC50 17.7 nM
CC1(N)CCN(c2cnc3c(-c4cccc(Cl)c4Cl)n[nH]c3c2)CC1 CHEMBL4762331 IC50 17.9 nM
C[C@@H]1OCC2(CCN(c3nc(N)c(Sc4cccnc4C(F)(F)F)c(=O)n3C)CC2)[C@@H]1N CHEMBL4476848 IC50 18.0 nM
CC1(CN)CCN(c2nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]2)CC1 CHEMBL5196141 IC50 20.0 nM
CC1(NCc2ccc(C(=O)NCc3ccc(/C=C/C(=O)NO)cc3)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5189911 IC50 20.4 nM
Cc1nc2c(N3CCCCC3)n[nH]c2nc1N1CCC2(CC1)Oc1ccc(F)cc1[C@H]2N CHEMBL5435176 IC90 21.0 nM
CNc1nccc(-c2n[nH]c3nc(N4CCC5(CC4)CO[C@@H](C)[C@H]5N)n(C)c(=O)c23)c1Cl CHEMBL4436233 IC50 22.0 nM
CC1(CN)CCN(c2cnc(Sc3cccc(N)c3Cl)c(N)n2)CC1 CHEMBL4795635 IC50 22.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(=O)(O)O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(N)=O CHEMBL5087443 Kd 22.0 nM
Cn1ccc2c(c1=O)CCCN2c1n[nH]c2nc(N3CCC4(CC3)Cc3ccccc3[C@H]4N)cnc12 CHEMBL5435965 IC90 22.0 nM
CC1(N)CCN(c2nc3sc(-c4cccc(Cl)c4Cl)nn3c2CO)CC1 CHEMBL4757856 IC50 22.3 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)cnc1-c1ccc(OCCOCCOCCCOCCCOCCCOCCCOCCOCCNCC(=O)COc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)c(Cl)c1Cl CHEMBL5178879 IC50 22.5 nM
CC1(NCc2ccc(C(=O)NO)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5203477 IC50 22.8 nM
CC1(CN)CCN(c2cnc(Sc3ccnc(N)c3Cl)c(N)n2)CC1 CHEMBL4784611 IC50 23.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(OP(=O)(O)O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CCCCC[N+]1=C(/C=C/C=C2/N(C)c3ccccc3C2(C)C)C(C)(C)c2ccccc21)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O CHEMBL5078939 Kd 23.0 nM
C[C@@H]1OCC2(CCN(c3nc(N)c(Sc4cccnc4C(F)(F)F)c(=O)n3O)CC2)[C@@H]1N CHEMBL5269504 IC50 23.0 nM
N[C@@H]1c2ccccc2OC12CCN(c1nc3[nH]nc(N4CCCc5ncccc54)c3nc1C(F)F)CC2 CHEMBL5406703 IC90 23.0 nM
N[C@@H]1c2cccnc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5396427 IC90 24.0 nM
CC1(NCc2ccc(C(=O)Nc3ccccc3N)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5198296 IC50 24.6 nM
CC1(N)CCN(c2cnc(Sc3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL4762625 IC50 25.0 nM
C[C@@H]1OCC2(CCN(c3ncc(Sc4cccnc4C(F)(F)F)c(=O)n3C)CC2)[C@@H]1N CHEMBL4531137 IC50 26.0 nM
N#Cc1ccc2c(c1)CC1(CCN(c3cnc4c(N5CCCc6ncccc65)n[nH]c4n3)CC1)[C@@H]2N CHEMBL5424347 IC90 26.0 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(Sc5ccnc(N)c5Cl)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4570587 IC50 27.0 nM
N[C@@H]1c2ccccc2OC12CC1CCC(C2)N1c1cnc2c(N3CCCc4ncccc43)n[nH]c2n1 CHEMBL5406899 IC90 27.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)Cc4cc(F)ccc4[C@H]5N)cnc3n2)c1Cl CHEMBL5409912 IC50 27.0 nM
Cc1nccc(Sc2c(N)nc(N3CCC4(CC3)CO[C@@H](C)[C@H]4N)n(C)c2=O)c1Cl CHEMBL4442335 IC50 28.0 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccnc(Cl)c5Cl)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4461938 IC50 28.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)Cc4ccccc4[C@H]5N)cnc3n2)c1Cl CHEMBL5424566 IC50 28.0 nM
CC1(CN)CCN(c2cnc(Sc3cccnc3C(F)(F)F)c(N)n2)CC1 CHEMBL4750422 IC50 29.0 nM
CC1(NCc2cccc(C(=O)NO)c2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5181150 IC50 29.0 nM
N[C@@H]1c2ccccc2C[C@]12CC[C@H](c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5399556 IC90 29.0 nM
Cn1c(N2CCC3(CCC[C@H]3N)CC2)nc2[nH]nc(-c3cccc(Cl)c3Cl)c2c1=O CHEMBL4437876 IC50 30.0 nM
COc1cccc(/N=C(\N)N2CCN(c3cnc(-c4cccc(Cl)c4Cl)c(N)n3)CC2)c1 CHEMBL5423012 IC50 30.4 nM
C[C@@H]1OCC2(CCN(c3ncc(Sc4cccnc4C(F)(F)F)c(=O)[nH]3)CC2)[C@@H]1N CHEMBL4447768 IC50 31.0 nM
COc1ccc(-n2cc(-c3ccc4ccc(=O)oc4c3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4750435 IC50 31.0 nM
CC1(CN)CCN(c2cnc3c(N4CCCc5ncccc54)n[nH]c3n2)CC1 CHEMBL5429843 IC50 31.0 nM
CN(C)C(=O)c1cc2cnc(Nc3nccc(Sc4cnc(N5CCC(C)(N)CC5)cn4)c3Cl)nc2n1C1CCCC1 CHEMBL5204959 IC50 31.3 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccnc(N)c5Cl)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4539178 IC50 32.0 nM
CC1(N)CCN(c2nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]2)CC1 CHEMBL5179772 IC50 32.0 nM
CC1(N)CCN(c2cnc3nc(Sc4ccnc(N)c4Cl)ccc3n2)CC1 CHEMBL5422687 IC50 33.0 nM
Cn1c(N2CCC(C)(CN)CC2)nc2[nH]nc(-c3cccc(Cl)c3Cl)c2c1=O CHEMBL4539145 IC50 34.0 nM
Cc1nc(N2CCC3(CCC[C@H]3N)CC2)c2cncn2c1-c1cccc(Cl)c1Cl CHEMBL4746963 IC50 34.0 nM
NC[C@]1(c2ccsc2)[C@@H]2CCN(c3cnc4c(-c5cccnc5C(F)(F)F)n[nH]c4n3)C[C@@H]21 CHEMBL5277819 IC50 34.0 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(Sc4cnc(N5CCC6(CC5)Cc5ccccc5[C@H]6N)cn4)c(Cl)n3)nc2n1C1CCCC1 CHEMBL5199829 IC50 34.1 nM
N#Cc1ccc(/N=C(\N)N2CCN(c3cnc(-c4cccc(Cl)c4Cl)c(N)n3)CC2)cc1 CHEMBL5415136 IC50 34.6 nM
N[C@@H]1c2c(F)cccc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5437460 IC90 35.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)Cc4cc(Cl)ccc4[C@H]5N)cnc3n2)c1Cl CHEMBL5417953 IC50 35.0 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccnc(NC6CC6)c5Cl)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4439006 IC50 36.0 nM
Cc1nc(N)ccc1-c1n[nH]c2nc(N3CCC4(CC3)CO[C@@H](C)[C@H]4N)n(C)c(=O)c12 CHEMBL4471006 IC50 37.0 nM
N[C@@H]1CCCC12CCN(c1cc(O)c(Sc3cccc(Cl)c3Cl)nc1CO)CC2 CHEMBL4740286 IC50 37.0 nM
CC1(N)CCN(c2cnc3c(Sc4ccccc4Cl)n[nH]c3n2)CC1 CHEMBL5395323 IC50 38.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)Cc4ncccc4[C@H]5N)cnc3n2)c1Cl CHEMBL5431126 IC50 38.0 nM
C[C@@H]1OCC2(CCN(c3cnc4c(-c5cccc(Cl)c5Cl)c[nH]c4n3)CC2)[C@@H]1N CHEMBL4475081 IC50 39.0 nM
Cc1ccc2c(n1)CC1(CCN(c3cnc4nc(Sc5ccnc(N)c5Cl)ccc4n3)CC1)[C@@H]2N CHEMBL5412395 IC50 40.0 nM
CC1(N)CCN(c2cnc3c(N4CCCc5ncccc54)n[nH]c3n2)CC1 CHEMBL5407072 IC50 41.0 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)c(Cl)c(=O)n1-c1cccc(Cl)c1Cl CHEMBL5188931 IC50 45.0 nM
CC1(N)CCN(c2nc3ncc(Sc4cccc(Cl)c4Cl)nc3[nH]2)CC1 CHEMBL5289332 IC50 47.0 nM
CCCCCCCCCOc1ccc(-c2ccc(CC(=O)O)cc2)cc1C(=O)O CHEMBL5403486 IC50 47.0 nM
CC1(N)CCN(c2cnc3nc(Sc4cccc(Cl)c4Cl)ccc3n2)CC1 CHEMBL5433311 IC50 47.0 nM
COc1ccc2c(c1)[C@@H](N)C1(CCN(c3cnc4nc(Sc5ccnc(N)c5Cl)ccc4n3)CC1)C2 CHEMBL5435347 IC50 47.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4cc(Sc5cnc(N6CCC7(CC6)CO[C@@H](C)[C@H]7N)cn5)ccn4)ncc3F)cc2n1C(C)C CHEMBL5195043 IC50 47.2 nM
N/C(=N\c1ccsc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5430657 IC50 48.1 nM
Cc1ccn([C@@]2(CN)[C@@H]3CN(c4cnc5c(-c6ccc7nn(C)cc7c6Cl)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5287742 IC50 49.0 nM
Cn1c(N2CCC3(CC2)COC[C@H]3N)nc2[nH]nc(-c3cccc(Cl)c3Cl)c2c1=O CHEMBL4459445 IC50 50.0 nM
COC(=O)c1cc(NC2=NC(=O)/C(=C/c3ccc(C)cc3)S2)ccc1O CHEMBL3786193 IC50 50.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)Cc4ncc(F)cc4[C@H]5N)cnc3n2)c1Cl CHEMBL5414521 IC50 50.0 nM
CN(C)C(=O)c1cc2cnc(Nc3ccc(Sc4cnc(N5CCC6(CC5)Cc5ccccc5[C@H]6N)cn4)c(Cl)c3)nc2n1C1CCCC1 CHEMBL5180571 IC50 52.1 nM
COc1ccc(/N=C(\N)N2CCN(c3cnc(-c4cccc(Cl)c4Cl)c(N)n3)CC2)cc1 CHEMBL5397714 IC50 52.7 nM
CNc1nccc(-c2n[nH]c3nc(N4CCC(C)(N)CC4)cnc23)c1Cl CHEMBL5170633 IC50 53.0 nM
N/C(=N\c1ccc(F)cc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5424940 IC50 53.3 nM
NC[C@]1(c2ccsc2)[C@@H]2CCN(c3nc4nc(Sc5cccnc5C(F)(F)F)cnc4[nH]3)C[C@@H]21 CHEMBL5278251 IC50 54.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4cnc5c(-c6cccnc6C(F)(F)F)n[nH]c5n4)C[C@@H]32)n1 CHEMBL5286868 IC50 55.0 nM
N[C@H]1CCCC12CCN(c1nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]1)CC2 CHEMBL5172365 IC50 56.0 nM
Cc1ccc2c(c1)[C@@H](N)C1(CCN(c3cnc4nc(Sc5ccnc(N)c5Cl)ccc4n3)CC1)C2 CHEMBL5424779 IC50 57.0 nM
CC1(N)CCN(c2cnc(Sc3ccccc3Br)c(N)n2)CC1 CHEMBL5196225 IC50 59.0 nM
O=C1/C(=N\Nc2ccc(S(=O)(=O)O)cc2)C(c2ccc([N+](=O)[O-])cc2)=NN1c1ccccc1 CHEMBL1765357 IC50 60.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC5(CC4)C[C@@H](O)C[C@H]5N)cnc3n2)c1Cl CHEMBL5433774 IC50 60.0 nM
COc1cnc2c(c1)[C@@H](N)C1(CCN(c3cnc4nc(Sc5ccnc(N)c5Cl)ccc4n3)CC1)C2 CHEMBL5437468 IC50 60.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4ccc(Sc5cnc(N6CCC7(CC6)CO[C@@H](C)[C@H]7N)cn5)c(Cl)c4)ncc3F)cc2n1C(C)C CHEMBL5200166 IC50 60.6 nM
CC1(CN)CCN(c2cnc3nc(Sc4ccnc(N)c4Cl)ccc3n2)CC1 CHEMBL5439836 IC50 61.0 nM
C[C@@H]1OCC2(CCN(c3nc4nc(Sc5cccnc5C(F)(F)F)cnc4[nH]3)CC2)[C@@H]1N CHEMBL5289545 IC50 64.0 nM
Nc1nccc(Sc2ccc3nc(N4C[C@H]5C[C@@H](C4)[C@H]5N)cnc3n2)c1Cl CHEMBL5416159 IC50 64.0 nM
N/C(=N\c1ccncc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5435971 IC50 64.5 nM
COc1ccc(-n2cc(-c3ccc(C(=O)O)cc3)c3cc(-c4ccc5nonc5c4)cnc32)cc1 CHEMBL4763014 IC50 65.0 nM
Cc1csc([C@@]2(CN)[C@@H]3CCN(c4cnc(Sc5cccnc5C(F)(F)F)c(N)n4)C[C@@H]32)n1 CHEMBL5270502 IC50 65.0 nM
N#Cc1cccc2c1CC1(CCN(c3cnc4c(N5CCCc6ncccc65)n[nH]c4n3)CC1)[C@@H]2N CHEMBL5417845 IC90 66.0 nM
Cn1c(N2CCC(C)(N)CC2)nc2[nH]nc(-c3cccc(Cl)c3Cl)c2c1=O CHEMBL4469071 IC50 67.0 nM
CC1(N)CCN(c2cnc(Sc3cccnc3C(F)(F)F)c(N)n2)CC1 CHEMBL4756767 IC50 67.0 nM
NC[C@]1(c2ccccn2)[C@@H]2CCN(c3cnc(Sc4cccnc4C(F)(F)F)c(N)n3)C[C@@H]21 CHEMBL5275625 IC50 68.0 nM
Nc1nc(N2CCC3(CCC[C@H]3N)CC2)cnc1-c1cccc(Cl)c1Cl CHEMBL4752507 IC50 70.0 nM
CC1(N)CCN(c2cnc(Sc3ccccc3Cl)c(N)n2)CC1 CHEMBL4746224 IC50 70.0 nM
O=C1/C(=N\Nc2ccc(S(=O)(=O)O)cc2)C(c2ccc([N+](=O)[O-])cc2)=NN1c1ccc([N+](=O)[O-])cc1 CHEMBL4762771 IC50 70.0 nM
Nc1nccc(Sc2ccc3nc(N4[C@H]5CC[C@H]4CC(N)C5)cnc3n2)c1Cl CHEMBL5434472 IC50 70.0 nM
O=C1/C(=N/Nc2ccc(S(=O)(=O)O)cc2)C(c2ccc([N+](=O)[O-])cc2)=NN1c1ccc([N+](=O)[O-])cc1 CHEMBL5182949 IC50 71.0 nM
Cc1nc(N2CCC(C)(N)CC2)c(CO)nc1-c1cccc(Cl)c1Cl CHEMBL5280755 IC50 71.0 nM
C[C@@H]1OCC2(CCN(c3cnc4nc(Sc5ccnc(N)c5Cl)ccc4n3)CC2)[C@@H]1N CHEMBL5422905 IC50 72.0 nM
N#Cc1cc(/N=C(\N)N2CCN(c3cnc(-c4cccc(Cl)c4Cl)c(N)n3)CC2)cs1 CHEMBL5396396 IC50 72.8 nM
CC1(N)CCN(c2nc3ncc(Sc4cccnc4C(F)(F)F)nc3[nH]2)CC1 CHEMBL5266583 IC50 74.0 nM
N#Cc1ccc(/N=C(\N)N2CCN(c3cnc(-c4cccc(Cl)c4Cl)c(N)n3)CC2)cn1 CHEMBL5431659 IC50 74.2 nM
COc1ccc(-n2cc(-c3ccc4nonc4c3)c3cc(-c4ccc(NS(C)(=O)=O)cc4)cnc32)cc1 CHEMBL4781443 IC50 75.0 nM
CC1(CN)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL4754023 IC50 76.0 nM
CC1(N)CCN(c2cnc(Sc3cccc(N)c3Cl)c(N)n2)CC1 CHEMBL4635178 IC50 76.2 nM
CC1(N)CCN(c2nc3[nH]nc(-c4ccccc4Cl)c3c(=O)[nH]2)CC1 CHEMBL5189709 IC50 78.0 nM
COc1ccccc1Sc1ncc(N2CCC(C)(N)CC2)nc1N CHEMBL5192102 IC50 79.0 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)c(CO)c(=O)n1-c1cccc(Cl)c1Cl CHEMBL5188744 IC50 87.0 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)c(C(N)=O)c(=O)n1-c1cccc(Cl)c1Cl CHEMBL5203457 IC50 89.0 nM
CC1(N)CCN(c2ncc(C(=O)Nc3cccnc3)c(N)n2)CC1 CHEMBL5440998 IC50 89.0 nM
N/C(=N\c1ccc(C(F)(F)F)cc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5421651 IC50 92.2 nM
CC1(N)CCN(c2cnc3nc(-c4cccc(Cl)c4Cl)ccc3n2)CC1 CHEMBL5437322 IC50 93.0 nM
NC[C@]1(c2ccccc2)[C@@H]2CCN(c3nc4nc(Sc5cccnc5C(F)(F)F)cnc4[nH]3)C[C@@H]21 CHEMBL5282533 IC50 94.0 nM
CC1(NCc2ccc(C(=O)Nc3ccc(/C=C/C(=O)NO)cc3)cc2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5186922 IC50 96.8 nM
O=C(O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 CHEMBL559337 IC50 97.0 nM
CC(=O)Nc1cccc(Sc2ncc(N3CCC(C)(N)CC3)nc2N)c1Cl CHEMBL4634350 IC50 98.7 nM
C[C@@H]1OCC2(CCC(c3cnc4nc(Sc5ccnc(N6CCCC6)c5Cl)ccc4n3)CC2)[C@@H]1N CHEMBL4745519 IC50 100.0 nM
CC1(N)CCN(c2cnc3c(Nc4ccnc(N)c4Cl)n[nH]c3n2)CC1 CHEMBL5431956 IC50 100.0 nM
CC1(N)CCN(c2nc3[nH]nc(-c4cccc(Cl)c4)c3c(=O)[nH]2)CC1 CHEMBL5196693 IC50 101.0 nM
CNC1(C)CCN(c2cnc3nc(Sc4ccnc(N)c4Cl)ccc3n2)CC1 CHEMBL5412473 IC50 101.0 nM
CC1(NCCCCC(=O)NO)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5198536 IC50 102.0 nM
Nc1nccc(Sc2ccc3nc(N4CCC[C@H](N)CC4)cnc3n2)c1Cl CHEMBL5432517 IC50 102.0 nM
COc1cccc(Sc2ccc3nc(N4CCC(C)(N)CC4)cnc3n2)c1Cl CHEMBL5395964 IC50 104.0 nM
Cn1c(N2CCC(C)(N)CC2)nc(N)c(-c2cccc(Cl)c2Cl)c1=O CHEMBL4440701 IC50 105.0 nM
CC1(N)CCN(c2nc3[nH]cc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]2)CC1 CHEMBL5198852 IC50 105.0 nM
NCC1CCN(c2cnc(Sc3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5176754 IC50 110.0 nM
COc1ccccc1/N=C(\N)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5417082 IC50 112.3 nM
COc1ccc(-n2cc(-c3ccc(C(F)(F)F)cc3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4742016 IC50 120.0 nM
CC1(N)CCN(c2cnc3c(-c4cccc(Cl)c4F)n[nH]c3n2)CC1 CHEMBL4776940 IC50 120.0 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)cc(=O)n1-c1cccc(Cl)c1Cl CHEMBL5196403 IC50 122.0 nM
CC1(N)CCN(c2nc3[nH]nc(-c4ccccc4)c3c(=O)[nH]2)CC1 CHEMBL5182453 IC50 129.0 nM
COc1ccc(-n2cc(-c3ccc([N+](=O)[O-])cc3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4755222 IC50 130.0 nM
CC1(N)CCN(c2cnc3c(N4CCCc5ccccc54)n[nH]c3n2)CC1 CHEMBL5402788 IC50 130.0 nM
N/C(=N\c1ccccc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5416270 IC50 137.1 nM
O=C(O)c1ccc(-c2cnc3c(c2)c(-c2ccc4nonc4c2)cn3-c2ccccc2)cc1 CHEMBL4741433 IC50 140.0 nM
N/C(=N\c1cccnc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5433260 IC50 142.0 nM
CNC1(C)CCN(c2nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]2)CC1 CHEMBL5208899 IC50 147.0 nM
N#Cc1ccc(/N=C(\N)N2CCN(c3cnc(Sc4cccnc4C(F)(F)F)c(N)n3)CC2)cc1 CHEMBL5396867 IC50 158.6 nM
COC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 CHEMBL1556914 IC50 161.0 nM
Nc1nc(N2CCC3(CCC[C@@H]3N)CC2)cnc1Sc1cccnc1C(F)(F)F CHEMBL4778151 IC50 166.0 nM
N[C@@H]1c2ccccc2OC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5412197 IC50 170.0 nM
CC1(N)CCN(c2cnc(Sc3cccc4ccccc34)c(N)n2)CC1 CHEMBL5169327 IC50 175.0 nM
C[C@@H]1OCC2(CCN(c3ccc(Sc4cccnc4C(F)(F)F)c(=O)n3C)CC2)[C@@H]1N CHEMBL4468062 IC50 177.0 nM
CC1(N)CCN(c2cnc(Sc3ccccc3C(F)(F)F)c(N)n2)CC1 CHEMBL5187708 IC50 178.0 nM
CCC/C=C/C=C/CCc1cc(O)cc(O)c1C(=O)O CHEMBL4075516 IC50 180.0 nM
CC1(CN)CCN(c2ncc(Sc3cccnc3C(F)(F)F)c(=O)[nH]2)CC1 CHEMBL4523033 IC50 181.0 nM
N/C(=N\c1ccccn1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5408024 IC50 183.6 nM
N[C@@H]1c2ncccc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5432538 IC90 190.0 nM
C[C@H](O)c1nc2c(N3CCCc4ncccc43)n[nH]c2nc1N1CCC2(CC1)Oc1ccccc1[C@H]2N CHEMBL5437742 IC90 190.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3ccc(-c4ccsc4)cc3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319356 IC50 200.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4cnc(Sc5cnc(N6CCC7(CC6)CO[C@@H](C)[C@H]7N)cn5)c(Cl)c4)ncc3F)cc2n1C(C)C CHEMBL5176602 IC50 205.1 nM
CC1(N)CCN(c2ncc(Sc3cccc(Cl)c3Cl)n3nccc23)CC1 CHEMBL5426696 IC50 208.0 nM
CC1(N)CCN(c2nc3[nH]nc(-c4ccnc(Cl)c4Cl)c3c(=O)[nH]2)CC1 CHEMBL5202318 IC50 210.0 nM
N/C(=N\c1cncnc1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5424837 IC50 210.4 nM
CCCCCCCCCOc1ccc(-c2ccc(CC(=O)O)cc2)c(C(=O)O)c1 CHEMBL5430697 IC50 216.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3ccc(-c4ccc(C#N)cc4)cc3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319376 IC50 220.0 nM
CC1(N)CCN(c2nc3[nH]nc(-c4ccncc4Cl)c3c(=O)[nH]2)CC1 CHEMBL5174916 IC50 225.0 nM
COc1ccc(-n2cc(-c3ccc4nonc4c3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4747136 IC50 240.0 nM
CC1(N)CCN(c2ncc(C(=O)Nc3ccc(Cl)c(Cl)c3)c(N)n2)CC1 CHEMBL5420523 IC50 250.0 nM
N/C(=N\c1cccs1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5402661 IC50 252.3 nM
C[C@@H]1OCC2(CCN(c3nc4[nH]nc(-c5ccnc(NC6CCC6)c5Cl)c4c(=O)n3C)CC2)[C@@H]1N CHEMBL4450282 IC50 260.0 nM
CC1(N)CCN(c2ncc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL4445214 IC50 260.0 nM
CC1(N)CCN(c2cnc3nc(Sc4cccc(C#N)c4Cl)ccc3n2)CC1 CHEMBL5436251 IC50 273.0 nM
O=C(O)c1cc(O)c(=O)c2c(O)c(O)c(F)cc2c1 CHEMBL4467577 IC50 277.0 nM
N[C@@H]1CCCC12CCN(c1nc3nc(Sc4cccnc4C(F)(F)F)cnc3[nH]1)CC2 CHEMBL5268861 IC50 290.0 nM
CC1(N)CCN(c2cnc3nc(-c4cccc5ccccc45)ccc3n2)CC1 CHEMBL5433596 IC50 291.0 nM
O=S(=O)(O)c1ccc2cc(/N=N/c3cc(S(=O)(=O)O)c4cccnc4c3O)ccc2c1 CHEMBL472004 IC50 295.0 nM
O=S(=O)([O-])c1ccc2cc(/N=N/c3cc(S(=O)(=O)[O-])c4cccnc4c3O)ccc2c1 CHEMBL501993 IC50 300.0 nM
CC1(N)CCN(c2nnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL4540461 IC50 300.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3ccc(-c4cccc(C#N)c4)cc3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319377 IC50 310.0 nM
C[C@]1(CN)CC[C@@H](c2cnc3c(N4CCCc5ncccc54)n[nH]c3n2)CC1 CHEMBL5426862 IC50 310.0 nM
CCN1CCN(C(=S)c2ccc(Cl)cc2)CC1 CHEMBL1410244 IC50_Mean 318.0 nM
O=S(=O)(O)c1cc(/N=N\c2ccc3cc(SOOO)ccc3c2)c(O)c2ncccc12 CHEMBL3692124 IC50 318.0 nM
CCOC(=O)C1=C(C)N=c2s/c(=C/c3ccco3)c(=O)n2C1c1ccco1 CHEMBL5196191 IC50 320.0 nM
O=S(=O)(O)c1cc(O)c2cc(Nc3ccccc3)ccc2c1 CHEMBL1271266 IC50_Mean 335.0 nM
CC1(N)CCN(c2cnc3nc(Oc4cccc(Cl)c4Cl)ccc3n2)CC1 CHEMBL5409926 IC50 342.0 nM
CC1(N)CCN(c2cnc3nc(-c4cccc(F)c4Cl)ccc3n2)CC1 CHEMBL5420264 IC50 344.0 nM
CN(C)C1(C)CCN(c2nc3[nH]nc(-c4cccc(Cl)c4Cl)c3c(=O)[nH]2)CC1 CHEMBL5181129 IC50 350.0 nM
COc1nccc(Sc2ccc3nc(N4CCC(C)(N)CC4)cnc3n2)c1Cl CHEMBL5396004 IC50 355.0 nM
NC[C@]1(c2ccccc2)[C@@H]2CCN(c3cnc(Sc4cccnc4C(F)(F)F)c(N)n3)C[C@@H]21 CHEMBL5290376 IC50 360.0 nM
Cc1nc(N2CCC3(CC2)CO[C@@H](C)[C@H]3N)c(C(F)(F)F)c(=O)n1-c1cccc(Cl)c1Cl CHEMBL5197330 IC50 366.0 nM
CCc1ccc(OCC(=O)Nc2ccc(-c3nc4ccccc4o3)c(O)c2)cc1 CHEMBL1329712 IC50_Mean 368.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3ccccc3-c3ccc(CO)o3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319378 IC50 370.0 nM
Cc1csc([C@]2(CN)[C@@H]3CN(c4cnc5c(-c6cccc(Cl)c6Cl)n[nH]c5n4)CC[C@@H]32)n1 CHEMBL5288787 IC50 370.0 nM
O=C(O)Cc1cccc(O)c(=O)c1C(=O)O CHEMBL1724282 IC50_Mean 376.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3cccc(-c4ccco4)c3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319379 IC50 380.0 nM
COc1ccc(-n2cc(-c3ccc(C#N)cc3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4783825 IC50 390.0 nM
N/C(=N\c1cnccn1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5400948 IC50 395.6 nM
O=C1C=CC(=O)C(c2cc(Cl)ccc2Cl)=C1 CHEMBL5289244 IC50 400.0 nM
CC1(N)CCN(c2cnc3nc(Sc4cccn5nccc45)ccc3n2)CC1 CHEMBL5414073 IC50 401.0 nM
Cc1nnc2sc(-c3ccc(NC(=O)c4ccc(-c5ccc(Cl)cc5Cl)o4)cc3)nn12 CHEMBL1350887 IC50_Mean 409.0 nM
Cn1c(N2CCC(C)(N)CC2)nc2nc(Sc3cccnc3C(F)(F)F)cnc21 CHEMBL5283114 IC50 409.0 nM
Cc1ccc(N2N=C(c3ccc([N+](=O)[O-])cc3)/C(=N/Nc3ccc(S(=O)(=O)O)cc3)C2=O)cc1 CHEMBL4784105 IC50 410.0 nM
COc1ccc(-n2cc(-c3ccc([N+](=O)[O-])cc3)c3cc(-c4cccc(C(=O)O)c4)cnc32)cc1 CHEMBL4795725 IC50 410.0 nM
COc1ccc(-n2cc(-c3ccc4nonc4c3)c3cc(-c4cccc(C(=O)O)c4)cnc32)cc1 CHEMBL4749307 IC50 410.0 nM
N=C(N)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5422106 IC50 414.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3cccc(-c4ccc(C#N)cc4)c3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319380 IC50 420.0 nM
NCC1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5175853 IC50 425.0 nM
C[C@@H]1OCC2(CCN(c3cc(N)c(Sc4cccnc4C(F)(F)F)c(=O)n3C)CC2)[C@@H]1N CHEMBL4546245 IC50 429.0 nM
CN1CCN(C(=S)C(=O)Nc2ccc(Br)cc2)CC1 CHEMBL1504939 IC50_Mean 431.0 nM
NC1CCCN(c2nc3nc(Sc4cccnc4C(F)(F)F)cnc3[nH]2)C1 CHEMBL5291140 IC50 435.0 nM
Cc1nc2nc(N3CCC(C)(N)CC3)[nH]c2nc1Sc1cccc(Cl)c1Cl CHEMBL5280924 IC50 436.0 nM
O=C(CSc1nc(-c2ccc(F)cc2)nc2c1Cc1ccccc1O2)Nc1cccc(C(=O)O)c1 CHEMBL1370165 IC50_Mean 443.0 nM
CC(C)(C)C#Cc1cc(-c2ccc(/C=C/C(=O)O)cc2Cl)ccc1O CHEMBL459711 IC50 450.0 nM
O=C(Nc1cc([N+](=O)[O-])ccc1O)c1cccc(C(=O)Nc2cc([N+](=O)[O-])ccc2O)c1 CHEMBL1461216 IC50_Mean 456.0 nM
COc1ccc(OC)c(N2C(=O)[C@@H]3C(c4ccccc4Cl)=NO[C@@H]3C2=O)c1 CHEMBL1433062 IC50_Mean 469.0 nM
CC1(N)CCN(c2cnc(Sc3ccccc3F)c(N)n2)CC1 CHEMBL5194002 IC50 484.0 nM
O=P(O)(Cc1cc2c(O)c(c1)S(=O)(=O)c1cc(CP(=O)(O)c3ccccc3)cc(c1O)S(=O)(=O)c1cc(CP(=O)(O)c3ccccc3)cc(c1O)S(=O)(=O)c1cc(CP(=O)(O)c3ccccc3)cc(c1O)S2(=O)=O)c1ccccc1 CHEMBL4569405 IC50 500.0 nM
COc1ccc(N2N=C(c3ccc([N+](=O)[O-])cc3)/C(=N/Nc3ccc(S(=O)(=O)O)cc3)C2=O)cc1 CHEMBL4780471 IC50 500.0 nM
O=C(Nc1ccc(I)cc1)C(=O)Nc1ccc(NC(=O)C(c2ccccc2)S(=O)(=O)O)cc1 CHEMBL3609373 Ki 510.0 nM
Cc1nc(N2CCC(C)(N)CC2)cc(=O)n1-c1cccc(Cl)c1Cl CHEMBL5170882 IC50 517.0 nM
O=C(O)C(S)C(S)C(=O)O CHEMBL28721 IC50_Mean 518.0 nM
CC1(N)CCN(c2nc3ncc(Oc4cccc(Cl)c4Cl)nc3[nH]2)CC1 CHEMBL5269591 IC50 521.0 nM
CC(=O)c1ccc(S(=O)(=O)Nc2cccc(-n3cnnn3)c2)cc1 CHEMBL1503182 IC50_Mean 526.0 nM
CC1(N)CCN(c2ccnc3c(Sc4cccc(Cl)c4Cl)cnn23)CC1 CHEMBL5436458 IC50 530.0 nM
CCCNC(=O)COc1ccc(-c2oc3cc(O)c(C(=O)O)cc3c2C#Cc2cccc(Cl)c2)cc1 CHEMBL2396718 IC50 560.0 nM
N[C@@H]1c2cnccc2CC12CCN(c1cnc3c(N4CCCc5ncccc54)n[nH]c3n1)CC2 CHEMBL5412065 IC90 570.0 nM
COc1ccc(-n2cc(-c3ccc4c(c3)COC4=O)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4777804 IC50 580.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(SCCN1CCCCC1)n2CCCc1ccccc1 CHEMBL1569991 IC50_Mean 599.0 nM
O=C(O)c1cc2c(C#Cc3ccc(Oc4ccccc4)cc3)c(-c3ccccc3)oc2cc1O CHEMBL2316908 IC50 600.0 nM
Cc1c(C)n(C(=O)CSc2nc3ccccc3[nH]2)c2ccccc12 CHEMBL1304345 IC50_Mean 603.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4ccc(Cl)c(Sc5cnc(N6CCC7(CC6)CO[C@@H](C)[C@H]7N)cn5)n4)ncc3F)cc2n1C(C)C CHEMBL5172609 IC50 618.3 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3ccc(-c4ccccc4)cc3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319357 IC50 620.0 nM
CC1(N)CCN(c2ncc(C(=O)Nc3ccc(F)cc3)c(N)n2)CC1 CHEMBL5402768 IC50 620.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3cccc(-c4ccsc4)c3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319381 IC50 630.0 nM
CCOC(=O)c1ccc(N2N=C(c3ccc([N+](=O)[O-])cc3)/C(=N/Nc3ccc(S(=O)(=O)O)cc3)C2=O)cc1 CHEMBL4757579 IC50 630.0 nM
CCOC(=O)c1ccc(N2NC(c3ccc([N+](=O)[O-])cc3)/C(=N/Nc3ccc(S(=O)(=O)O)cc3)C2=O)cc1 CHEMBL5270661 IC50 630.0 nM
CC1(N)CCN(c2cnc3c(Sc4cccc(Cl)c4Cl)cnn3c2)CC1 CHEMBL5427793 IC50 634.0 nM
CCCCCCN(Cc1ccc(C#Cc2ccc(CCCC)cc2)cc1)c1ccc(O)c(C(=O)O)c1 CHEMBL4063482 Ki 652.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3ccc(OCc4ccccc4)c(Cl)c3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319358 IC50 660.0 nM
NC1CCN(c2nc3nc(Sc4cccnc4C(F)(F)F)cnc3[nH]2)CC1 CHEMBL5269651 IC50 664.0 nM
COc1ccccc1NS(=O)(=O)c1cc(NC(=O)c2sccc2C)ccc1N1CCCC1 CHEMBL1463248 IC50_Mean 665.0 nM
Cc1nc2c(F)cc(-c3nc(Nc4ccc(Sc5cnc(N6CCC7(CC6)Cc6ccccc6[C@H]7N)cn5)c(Cl)n4)ncc3F)cc2n1C(C)C CHEMBL5184331 IC50 673.0 nM
COc1ccc(NC(=S)N(CCC(C)C)C2CCN(C(C)C)CC2)cc1Cl CHEMBL1385949 IC50_Mean 676.0 nM
CN1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5171642 IC50 695.0 nM
O=C(O)CCC(=O)N1CCc2cc(S(=O)(=O)N3CCN(c4cccc(Cl)c4)CC3)ccc21 CHEMBL3693872 IC50 700.0 nM
CCCCCCCCCC[C@@H](C)C(=O)C1=C2C3=COC(C)=CC3=CC(=O)[C@]2(C)OC1=O CHEMBL5208593 IC50 700.0 nM
CC1(N)CCN(c2cnc3cc(-c4cccc(Cl)c4Cl)ccc3n2)CC1 CHEMBL5420479 IC50 705.0 nM
CCN1CCN(C(=S)c2ccc(O)cc2)CC1 CHEMBL1489399 IC50_Mean 712.0 nM
Nc1nc(N2CCNCC2)cnc1-c1cccc(Cl)c1Cl CHEMBL5194617 IC50 712.0 nM
CC1(NCc2cn(CCOCCOCCOCCOCCNc3cccc4c3C(=O)N(C3CCC(=O)NC3=O)C4=O)nn2)CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5190061 IC50 714.0 nM
N/C(=N\c1ncccn1)N1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5410896 IC50 715.3 nM
O=C1/C(=N/Nc2ccc(S(=O)(=O)O)cc2)C(c2ccc([N+](=O)[O-])cc2)=NN1c1ccccc1 CHEMBL5288934 Ki 730.0 nM
CCCCCn1c(N)c(-c2nc3ccccc3o2)c2c([N+](=O)[O-])nn(C)c(=O)c21 CHEMBL1381413 IC50_Mean 738.0 nM
CC1(N)CCN(c2cnc(Sc3cccc(Cl)c3)c(N)n2)CC1 CHEMBL5176429 IC50 747.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3nc4ccc(Br)cc4s3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319359 IC50 760.0 nM
Cc1ccc(-c2nc(NC(=O)CSc3cc(C)c4ccccc4n3)ns2)cc1 CHEMBL1453902 IC50_Mean 770.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3cccc(-c4ccccc4)c3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319360 IC50 770.0 nM
CC(C)OCCCN=C(S)Nc1ccc(S(N)(=O)=O)cc1 CHEMBL1432675 IC50_Mean 771.0 nM
Cc1ccc(S(=O)(=O)Cc2ccc(C(=O)O)o2)cc1 CHEMBL1580036 IC50_Mean 776.0 nM
CC1(N)CCN(c2nc3ncc(-c4cccc(Cl)c4Cl)nc3[nH]2)CC1 CHEMBL5290199 IC50 797.0 nM
O=C1Nc2ccc(C(=O)O)cc2/C1=N/Nc1ccccc1C(=O)O CHEMBL526644 IC50 800.0 nM
CCCCCCCCCCCC(=O)C1=C2C3=COC(C)=CC3=CC(=O)[C@]2(C)OC1=O CHEMBL5209393 IC50 800.0 nM
O=C1Nc2ccc(S(=O)(=O)O)cc2/C1=N/Nc1ccccc1[N+](=O)[O-] CHEMBL502257 IC50 800.0 nM
CC1(N)CCN(c2ncc(C(=O)Nc3ccccn3)c(N)n2)CC1 CHEMBL5429374 IC50 800.0 nM
CC1(N)CCN(c2nc3cnc(Sc4cccnc4C(F)(F)F)nc3[nH]2)CC1 CHEMBL5275116 IC50 808.0 nM
CC1(N)CCN(c2cnc(Sc3ccccc3)c(N)n2)CC1 CHEMBL5189486 IC50 811.0 nM
CCN1CCN(C(=S)c2ccc(Cl)c(Cl)c2)CC1 CHEMBL1485717 IC50_Mean 843.0 nM
NCCC1CCN(c2cnc(-c3cccc(Cl)c3Cl)c(N)n2)CC1 CHEMBL5199730 IC50 858.0 nM
Cn1c(-c2cccc(NC(=O)C(=O)Nc3cccc(OCc4ccccc4)c3)c2)c(I)c2cc(C(=O)O)c(O)cc21 CHEMBL3319361 IC50 860.0 nM
CC1(N)CCN(c2nc3nc(Sc4cccnc4C(F)(F)F)cnc3s2)CC1 CHEMBL5288762 IC50 887.0 nM
COc1ccccc1NS(=O)(=O)c1cc(NC(S)=NCCN2CCOCC2)ccc1N1CCOCC1 CHEMBL1421470 IC50_Mean 891.0 nM
CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(OCC)c(C(=O)OC)c1 CHEMBL4164960 IC50 910.0 nM
CCOS(=O)(=O)/C=C/c1ccc(OCc2ccc(COc3ccc(/C=C/S(=O)(=O)OCC)cc3)c(C(=O)Nc3ccc(Oc4ccc(-c5ccccc5)cc4)cc3)c2)cc1 CHEMBL4094898 IC50 920.0 nM
COc1cccc(N2[C@@H](CC(=O)O)c3ccc(/C=C/C(=O)O)cc3S2(=O)=O)c1 CHEMBL1714422 IC50_Mean 933.0 nM
Cc1cc(C)c(NC(S)=NCC2CCN(C(C)c3ccccc3)C2)c(C)c1 CHEMBL1353918 IC50_Mean 934.0 nM
CCOS(=O)(=O)/C=C/c1ccc(OCc2ccc(COc3ccc(/C=C/S(=O)(=O)OCC)cc3)c(C(=O)Nc3ccc(Oc4ccc(Cl)cc4)cc3)c2)cc1 CHEMBL4087797 IC50 940.0 nM
O=C1/C(=N\Nc2ccc(S(=O)(=O)O)cc2)C(c2ccc([N+](=O)[O-])cc2)=NN1c1ccc(C(F)(F)F)cc1 CHEMBL4750975 IC50 940.0 nM
NC(=O)c1cc(O)c(=O)c2c(O)c(O)c(F)cc2c1 CHEMBL4459515 IC50 949.0 nM
O=C(N/N=C/c1ccoc1)c1cc(O)cc(O)c1 CHEMBL1964442 IC50_Mean 952.0 nM
COc1cc([C@H]2Oc3cc4c(cc3[C@@H]2CO)NC(=O)[C@@]4(O)CC#N)ccc1O CHEMBL5180338 EC50 970.0 nM
CC1(N)CCN(c2cnc(Sc3ccc4ccccc4c3)c(N)n2)CC1 CHEMBL5182415 IC50 976.0 nM
CCOC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 CHEMBL4447485 IC50 985.0 nM
CCOC(=O)c1sc(-c2ccc(OC)cc2)nc1COc1ccc(Cl)cc1 CHEMBL5208728 IC50 990.0 nM
COc1ccc(NC(S)=NCCN2CCC(C)CC2)cc1Cl CHEMBL1340607 IC50_Mean 999.0 nM