Cc1ccc(-n2c(N)c(C(=O)N3CCN(C)CC3)sc2=S)cc1 CHEMBL1605172 IC50 14.4 nM
NS(=O)(=O)c1ccc(NC(S)=NC2CCCCC2)cc1 CHEMBL1322542 IC50 25.0 nM
S=C(NCCc1ccccc1)Nc1c(Cl)cccc1Cl CHEMBL1408579 IC50 34.5 nM
CN1CCN(C(=O)c2sc(=S)n(-c3ccccc3)c2N)CC1 CHEMBL1304193 IC50 58.6 nM
NS(=O)(=O)c1cc(C(=O)NC2CCSc3ccccc32)ccc1Cl CHEMBL1460470 IC50 66.0 nM
COc1cc(C(=S)N2CCCCC2)ccc1O CHEMBL1608642 IC50 84.6 nM
Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)[C@H](O)c3ccccc3)[C@H]2SC1 CHEMBL1360024 IC50 100.0 nM
CCOC(=O)c1sc2nc3c(SCC(=O)O)cc(C(=O)c4ccccc4O)cn3c(=O)c2c1C CHEMBL1445488 IC50 105.0 nM
Cc1cccc(-n2c(N)c(C(=O)N3CCN(C)CC3)sc2=S)c1 CHEMBL1505246 IC50 108.0 nM
O=C(O)c1ccccc1-c1c2ccc(=O)c([As]3SCCS3)c-2oc2c([As]3SCCS3)c(O)ccc12 CHEMBL454668 IC50 125.0 nM
O=c1/c(=C/c2ccco2)sc2nc3cc(Br)cnc3n12 CHEMBL1603381 IC50 127.0 nM
S=C(c1cn(CCOc2ccccc2)c2ccccc12)N1CCCC1 CHEMBL1407203 IC50 129.0 nM
COc1ccc(-n2cc(-c3ccc4ccc(=O)oc4c3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 CHEMBL4750435 IC50 130.0 nM
O=C(O)c1ccccc1-c1ccc(/C=c2\sc3nc4cc(Br)cnc4n3c2=O)o1 CHEMBL1371869 IC50 159.0 nM
O=c1/c(=C/c2ccccc2Cl)sc2nc3cc(Br)cnc3n12 CHEMBL1448629 IC50 180.0 nM
O=C(O)COc1ccc(/C=N/NC(=O)c2ccc(-c3csc(Nc4ccc(Cl)cc4)n3)cc2)cc1 CHEMBL1701224 IC50 193.0 nM
NS(=O)(=O)c1ccc(NC(=S)N2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1 CHEMBL1447397 IC50 196.0 nM
COCCNC(=O)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1501132 IC50 198.0 nM
O=C(O)C1Nc2c(O)cccc2C2C=CCC12 CHEMBL1527520 IC50 200.0 nM
O=C(O)C1Nc2ccccc2C2C=CCC12 CHEMBL492894 IC50 200.0 nM
CCOC(=O)c1sc2nc3c(SCCC(=O)O)cc(C(=O)c4cc(OC)ccc4O)cn3c(=O)c2c1C CHEMBL1536896 IC50 209.0 nM
O=C(O)c1ccc(NC(=S)NC(=O)c2ccc(-c3ccc(Br)cc3)o2)cc1 CHEMBL1393151 IC50 227.0 nM
COc1cc(/C=C2\SC(=O)N(CC(=O)Nc3ccc(C)cc3)C2=O)cc(Cl)c1OCC(=O)O CHEMBL1407368 IC50 256.0 nM
CCOC(=O)c1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 CHEMBL1334633 IC50 280.0 nM
CCc1ccc(NC2=NC(=O)/C(=C/c3cc(Br)c(OCC(=O)O)c(OC)c3)S2)cc1 CHEMBL1526088 IC50 280.0 nM
c1ccc(CSc2nnc(-c3ccco3)c(-c3ccco3)n2)cc1 CHEMBL1449836 IC50 284.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccc(Cl)cc2)n2c(sc(=Cc3ccc(OCC(=O)O)cc3)c2=O)=N1 CHEMBL1414679 IC50 304.0 nM
COc1ccc(/C=C2\SC(=S)N(CCC(=O)Nc3ccc(C(=O)O)cc3)C2=O)cc1OC CHEMBL1438889 IC50 312.0 nM
Clc1ccccc1CSc1nnc(-c2ccco2)c(-c2ccco2)n1 CHEMBL1371777 IC50 329.0 nM
COc1ccc(CN2C(=O)/C(=C/c3ccc(-c4ccc(Cl)c(C(=O)O)c4)o3)SC2=S)cc1 CHEMBL1327648 IC50 331.0 nM
N#C/C(=C\c1ccc(OCc2ccc(Br)cc2)cc1)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL1390354 IC50 343.0 nM
CCOc1cc(/C=C2/S/C(=N/c3ccc4ccccc4c3)NC2=O)cc(Cl)c1OCC(=O)O CHEMBL1732016 IC50 373.0 nM
COc1cc(/C=C2/SC(=S)N(c3cccc(C(=O)O)c3)C2=O)ccc1OCc1ccc(Cl)cc1 CHEMBL1704862 IC50 394.0 nM
CC1(C)CCCN(C(=O)c2coc(=O)c(Br)c2)C1 CHEMBL1539325 IC50 400.0 nM
CSc1nc(N(CCO)CCO)c2sc3nc(-c4ccco4)c4c(c3c2n1)CCC4 CHEMBL1324051 IC50 410.0 nM
Cc1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 CHEMBL1376870 IC50 410.0 nM
CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)cc3)c(=O)n2C1c1ccc(Cl)cc1 CHEMBL1424189 IC50 419.0 nM
COc1ccc(Br)cc1/C=c1\sc2nc(-c3ccco3)nn2c1=O CHEMBL1978364 IC50 420.0 nM
Cc1ccc(C)n1C(Cc1ccccc1)C(=O)O CHEMBL259355 IC50 420.0 nM
CC(C)(Oc1ccc2sc3ccccc3c2c1)C(=O)O CHEMBL1715328 IC50 450.0 nM
CCCCNC(=O)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1702580 IC50 452.0 nM
O=C(O)COc1ccc(Nc2ccccc2)cc1 CHEMBL1488869 IC50 465.0 nM
O=C(NCCc1ccccc1)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1725599 IC50 472.0 nM
O=C(NCCO)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1411862 IC50 476.0 nM
N#C/C(=C/c1ccc(OCc2ccc(C(=O)O)cc2)c(Br)c1)c1cccc(F)c1 CHEMBL1443268 IC50 481.0 nM
O=S(=O)([O-])c1ccc2cc(/N=N/c3cc(S(=O)(=O)[O-])c4cccnc4c3O)ccc2c1 CHEMBL501993 IC50 483.0 nM
CCCCCc1nnc(NC(=O)Cc2cccs2)s1 CHEMBL1353227 IC50 490.0 nM
O=C(NCCCO)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1374242 IC50 537.0 nM
CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(=O)O)cc3)c(=O)n2C1c1ccc(SC)cc1 CHEMBL1609429 IC50 537.0 nM
O=C(O)CCN1C(=O)/C(=C2\C(=O)N(Cc3ccccc3Cl)c3ccccc32)SC1=S CHEMBL1373132 IC50 549.0 nM
O=C(Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1)N1CCC(c2ccccc2)C1 CHEMBL1730460 IC50 550.0 nM
CCOc1ccc(-n2c(SCC(=O)N3CCc4ccccc43)nnc2-c2c[nH]c3ccccc23)cc1 CHEMBL1418840 IC50 556.0 nM
COc1cc(/C=C(\C#N)C(=O)Nc2cccc(C(=O)O)c2)ccc1OCc1ccc(Cl)cc1 CHEMBL1550429 IC50 557.0 nM
O=C(Nc1ccccc1)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1735214 IC50 575.0 nM
O=C(O)CSc1cc(C(=O)c2ccccc2O)cn2c(=O)c3c4c(sc3nc12)CCCC4 CHEMBL1372387 IC50 576.0 nM
CCc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(C(=O)O)cc3)C2=O)cc1 CHEMBL1413629 IC50 581.0 nM
NS(=O)(=O)c1ccc(NC(S)=NC2CC2)cc1 CHEMBL1569076 IC50 588.0 nM
Cc1ccc(NC(=O)CN2C(=O)S/C(=C\c3cc(Cl)c(OCC(=O)O)c(Cl)c3)C2=O)cc1 CHEMBL1373210 IC50 596.0 nM
O=C(O)CCCN1C(=O)/C(=C/c2ccc(-c3nc4ccccc4s3)o2)SC1=S CHEMBL1492305 IC50 608.0 nM
O=C1/C(=C/c2cn(-c3ccccc3)nc2-c2ccc(OCc3ccc(Cl)cc3)cc2)SC(=S)N1CCS(=O)(=O)O CHEMBL565795 IC50 620.0 nM
N#C/C(=C\c1ccc(OCc2ccc(Cl)cc2)cc1)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL1371816 IC50 651.0 nM
COc1ccc(NC(=S)N(CCC(C)C)C2CCN(C(C)C)CC2)cc1Cl CHEMBL1385949 IC50 662.0 nM
COc1cc(C(=S)NCc2ccccc2)ccc1O CHEMBL1702303 IC50 665.0 nM
CCOC(=O)CCNC(=O)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1714241 IC50 683.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccc(Cl)cc2)n2c(s/c(=C\c3ccc(OCC(=O)O)cc3)c2=O)=N1 CHEMBL1672291 Ki 690.0 nM
O=C(Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1)N1CCOCC1 CHEMBL1707169 IC50 693.0 nM
Cc1cc(NC(=O)Cc2cccs2)no1 CHEMBL578585 IC50 700.0 nM
CC(/C=C1\SC(=S)N(CCCC(=O)Nc2ccc(C(=O)O)c(O)c2)C1=O)=C\c1ccccc1 CHEMBL1384502 IC50 703.0 nM
Cc1cc(C(=O)O)ccc1-n1c(C)ccc1C CHEMBL1559731 IC50 760.0 nM
CCC(CC)NC(=S)c1ccc(O)c(OC)c1 CHEMBL1727475 IC50 766.0 nM
CCCCCCCCCCCCCCCCCCC#CCCCCCCCC(=O)O CHEMBL1400895 IC50 792.0 nM
CCCCCCCCCCCCCCCCCCC=CCCCCCC(=O)O CHEMBL1526353 IC50 801.0 nM
CC(=O)c1ccc(NC(=O)c2ccc3nc(-c4ccco4)c(-c4ccco4)nc3c2)cc1 CHEMBL1500600 IC50 805.0 nM
Cc1cc(C)c2nc3s/c(=C\c4ccc(-c5ccccc5C(=O)O)o4)c(=O)n3c2c1 CHEMBL1608654 IC50 805.0 nM
CNC(=O)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1713063 IC50 816.0 nM
Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 CHEMBL1362650 IC50 819.0 nM
O=C(OC1CCCCC1)c1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 CHEMBL1334684 IC50 840.0 nM
CC1CCN(C(=O)Nc2ccc3nc(-c4ccco4)c(-c4ccco4)nc3c2)CC1 CHEMBL1333996 IC50 840.0 nM
O=C(O)COc1ccccc1/C=N/NC(=O)c1ccc(-c2csc(Nc3ccc(Cl)cc3)n2)cc1 CHEMBL1719149 IC50 841.0 nM
O=C1/C(=C/c2cn(-c3ccccc3)nc2-c2ccc(OCc3ccccc3F)cc2)SC(=S)N1CCS(=O)(=O)O CHEMBL584481 IC50 870.0 nM
CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1 CHEMBL1632 IC50 920.0 nM
O=C(CSc1ccc2ccccc2n1)Nc1nsc(-c2ccc(Cl)cc2)n1 CHEMBL1568683 IC50 931.0 nM
O=C(Nc1ccc(Cl)cc1)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1729151 IC50 949.0 nM
O=C(c1ccc(=O)oc1)N1CCOCC1 CHEMBL1358848 IC50 990.0 nM