O=C(O)C1=C(C(=O)O)NC=CC1 CHEMBL3322297 Ki 1.6 nM
O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc([N+](=O)[O-])ccn1 CHEMBL134802 IC50 3.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccc(Cl)cc1 CHEMBL115651 IC50 6.0 nM
CCN1C(C)=C(C(=O)NCC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C1C(=O)O CHEMBL113736 IC50 8.28 nM
O=C(Nc1c(F)cccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc([N+](=O)[O-])ccn1 CHEMBL133911 IC50 9.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1cccc([N+](=O)[O-])c1 CHEMBL423509 IC50 10.0 nM
CCN1C(C)=C(C(=O)NCc2ccccc2)C(c2ccccc2Cl)C(C(=O)O)=C1C(=O)O CHEMBL326950 IC50 10.61 nM
CCN1C(C)=C(C(=O)OC(C)C)[C@@H](c2ccccc2)C(C(=O)O)=C1C(=O)O CHEMBL324288 Ki 11.0 nM
COc1ccc(CN2C(C)=C(C(=O)OC(C)C)C(c3ccccc3Cl)C(C(=O)O)=C2C(=O)O)cc1OC CHEMBL115341 IC50 11.0 nM
COc1ccnc(C(=O)Nc2cc3ccccc3cc2Oc2ccc(C(=O)O)c(C(=O)O)c2)c1 CHEMBL440528 IC50 12.0 nM
O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 CHEMBL133832 IC50 12.0 nM
CCN1C(C)=C(C(=O)NC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C1C(=O)O CHEMBL114226 IC50 12.9 nM
O=C(N[C@@H]1Cc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL139472 IC50 14.0 nM
CCNC(=O)C1=C(C)N(CC)C(C(=O)O)=C(C(=O)O)C1c1ccccc1Cl CHEMBL114846 IC50 19.9 nM
O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc([N+](=O)[O-])ccn1 CHEMBL132191 IC50 25.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccccc1 CHEMBL114731 IC50 26.0 nM
CCc1ccnc(C(=O)Nc2cc3ccccc3cc2Oc2ccc(C(=O)O)c(C(=O)O)c2)c1 CHEMBL133274 IC50 29.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1cccc(Cl)c1 CHEMBL113762 IC50 29.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(Cl)ccc3[nH]2)Cc2ccccc21 CHEMBL337332 IC50 32.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1cc(Cl)cc(Cl)c1 CHEMBL115441 IC50 37.0 nM
O=C(NC1Cc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL139461 IC50 38.0 nM
O=C(N[C@H]1Cc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL134854 IC50 39.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccc(Cl)c(Cl)c1 CHEMBL334272 IC50 41.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1CC(F)(F)F CHEMBL114271 IC50 52.0 nM
O=C(NC1CCc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL136327 IC50 55.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(Cl)cc(F)c3[nH]2)Cc2ccccc21 CHEMBL342880 IC50 55.0 nM
CN1C(=O)C(NC(=O)c2cc3ccccc3[nH]2)Cc2ccccc21 CHEMBL136218 IC50 56.0 nM
CN1C(=O)[C@@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)Cc2ccccc21 CHEMBL337012 IC50 57.0 nM
Cc1ccnc(C(=O)Nc2cc3ccccc3cc2Oc2ccc(C(=O)O)c(C(=O)O)c2)c1 CHEMBL133923 IC50 57.0 nM
CN1C(=O)[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)Cc2ccccc21 CHEMBL136182 IC50 58.0 nM
O=C(Nc1c(F)cccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 CHEMBL132640 IC50 60.0 nM
CN1C(=O)C(NC(=O)c2cc3ccc(Cl)cc3[nH]2)Cc2ccccc21 CHEMBL422632 IC50 69.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(Br)ccc3[nH]2)Cc2ccccc21 CHEMBL134793 IC50 73.0 nM
O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(C(F)(F)F)ccn1 CHEMBL337224 IC50 80.0 nM
O=C(N[C@@H]1CCc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL134797 IC50 83.0 nM
CN1C(=O)C(NC(=O)c2cc3cccc(Cl)c3[nH]2)Cc2ccccc21 CHEMBL136168 IC50 88.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(F)ccc3[nH]2)Cc2ccccc21 CHEMBL136573 IC50 89.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1cc(Cl)ccc1Cl CHEMBL117483 IC50 91.0 nM
Cc1ccc2[nH]c(C(=O)NC3Cc4ccccc4N(C)C3=O)cc2c1 CHEMBL136572 IC50 98.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(Cl)ccc3[nH]2)CCc2ccccc21 CHEMBL342364 IC50 105.0 nM
O=C(Nc1cc(F)ccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc([N+](=O)[O-])ccn1 CHEMBL133114 IC50 109.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(C#N)ccc3[nH]2)Cc2ccccc21 CHEMBL137196 IC50 110.0 nM
COc1ccnc(C(=O)Nc2c(F)cccc2Oc2ccc(C(=O)O)c(C(=O)O)c2)c1 CHEMBL133603 IC50 110.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)Nc3ccon3)cc2)nc2ccccc21 CHEMBL194177 IC50 110.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)NCc3cccs3)cc2)nc2ccccc21 CHEMBL194356 IC50 110.0 nM
CN1C(=O)C(NC(=O)c2cc3cccc([N+](=O)[O-])c3[nH]2)Cc2ccccc21 CHEMBL138822 IC50 120.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)NCc3ccco3)cc2)nc2ccccc21 CHEMBL194807 IC50 120.0 nM
CCN1C(C)=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C1C(=O)O CHEMBL114950 IC50 138.0 nM
O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cccc([N+](=O)[O-])c1 CHEMBL442404 IC50 140.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)NCc3cccs3)cc2)nc2cc(F)ccc21 CHEMBL193734 IC50 140.0 nM
O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3nc2O)cc1 CHEMBL196637 IC50 160.0 nM
N#Cc1ccnc(C(=O)Nc2ccccc2Oc2ccc(C(=O)O)c(C(=O)O)c2)c1 CHEMBL132201 IC50 167.0 nM
CC1=NC(C(=O)O)=C(C(=O)O)C(c2ccccc2Cl)/C1=C(\O)OC(C)C CHEMBL323707 IC50 172.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccccc1Cl CHEMBL326810 IC50 178.0 nM
O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 CHEMBL134152 IC50 181.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccc(Cl)cc1Cl CHEMBL115395 IC50 185.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)NCc3cccs3)cc2)nc2cccnc21 CHEMBL372862 IC50 190.0 nM
CCn1c(=O)c(Nc2ccc(C(=O)NCc3cccs3)cc2)nc2ccccc21 CHEMBL196687 IC50 190.0 nM
COc1ccnc(C(=O)Nc2ccccc2Oc2ccc(C(=O)O)c(C(=O)O)c2)c1 CHEMBL131644 IC50 200.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)Nc3cc[nH]n3)cc2)nc2ccccc21 CHEMBL196001 IC50 200.0 nM
CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1cccc(Cl)c1Cl CHEMBL115045 IC50 233.0 nM
O=C(N[C@H]1CCc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1 CHEMBL136712 IC50 240.0 nM
Cc1ccc2nc(Nc3ccc(C(=O)NCc4cccs4)cc3)c(=O)n(C)c2c1 CHEMBL440386 IC50 280.0 nM
O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCO)c2=O)cc1 CHEMBL382077 IC50 320.0 nM
O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCN3CCOCC3)c2=O)cc1 CHEMBL370173 IC50 350.0 nM
O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCN3CCCCC3)c2=O)cc1 CHEMBL373082 IC50 420.0 nM
O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(I)ccn1 CHEMBL132430 IC50 468.0 nM
Cn1c(=O)c(Nc2ccc(C(=O)Nc3nccs3)cc2)nc2ccccc21 CHEMBL194245 IC50 480.0 nM
O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(O)CC1)c1cc2cc(Cl)ccc2[nH]1 CHEMBL99889 IC50 500.0 nM
CN1C(=O)C(NC(=O)c2cc3cc(C(F)(F)F)ccc3[nH]2)Cc2ccccc21 CHEMBL337378 IC50 550.0 nM
O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCc3ccccn3)c2=O)cc1 CHEMBL372478 IC50 580.0 nM
O=C(Nc1cc(F)ccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 CHEMBL130055 IC50 647.0 nM
Cn1c(=O)c(Nc2ccc(NC(=O)c3ccno3)cc2)nc2ccccc21 CHEMBL371986 IC50 710.0 nM
CN(C)CCn1c(=O)c(Nc2ccc(C(=O)NCc3cccs3)cc2)nc2ccccc21 CHEMBL372696 IC50 710.0 nM
Cn1c(=O)c(Nc2ccc(NC(=O)c3ccon3)cc2)nc2ccccc21 CHEMBL425918 IC50 730.0 nM
O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1ccccn1 CHEMBL133109 IC50 844.0 nM
CCc1ccc2[nH]c(C(=O)NC3Cc4ccccc4N(C)C3=O)cc2c1 CHEMBL138069 IC50 850.0 nM
O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cccc([N+](=O)[O-])c1 CHEMBL326611 IC50 900.0 nM
CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CHEMBL428690 IC50 1000.0 nM