COc1cc(N(CC2CCCC2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCOCC1 CHEMBL5092802 IC50 0.1 nM
COc1cc(NC(=S)N(CCCn2cncc2C)C(C)C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5085353 IC50 0.3 nM
COc1cc(N(CC2CCCC2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCNCC1 CHEMBL5086776 IC50 0.46 nM
COc1cc(N(C(=S)NCCCn2cncc2C)C2CCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5085226 IC50 0.5 nM
COc1cc(N(C(=S)NCCCn2cncc2C)C2CCCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5075575 IC50 0.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCNCC1 CHEMBL4077433 IC50 0.7 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCCCN(C)C CHEMBL5089771 IC50 0.71 nM
COc1cc(N(C(=S)NCCCn2cncc2C)C2CCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5083519 IC50 0.8 nM
COc1cc(N(Cc2ccccc2)C(=O)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5088732 IC50 1.0 nM
COc1cc(N(CC2CCCC2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCN(C)CC1 CHEMBL5085670 IC50 1.0 nM
COc1ccc(N(Cc2ccc(F)cc2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4525926 IC50 1.3 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCNCC1 CHEMBL5089285 IC50 1.4 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCN1CCNCC1 CHEMBL5081653 IC50 1.5 nM
COc1ccc(N(CCCCc2ccnc(NCCN)c2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4445407 IC50 1.6 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCc1ccnc(N)c1 CHEMBL5081891 IC50 1.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCN1CCNCC1 CHEMBL5083687 IC50 1.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCc1ccnc(N)c1 CHEMBL5081537 IC50 1.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(NCCN)c1 CHEMBL4204093 IC50 1.8 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCN1CCN(C)CC1 CHEMBL5092925 IC50 1.8 nM
Cc1nn(C)c2cc(N(Cc3ccc(F)cc3)C(=O)NCCCn3cncc3C)ccc12 CHEMBL5266674 IC50 2.3 nM
Cc1n[nH]c2ccc(N(C(=O)NCCCn3cncc3C)C3CCCCC3)cc12 CHEMBL5279792 IC50 2.3 nM
COc1ccc(C2(C(=S)NCCCn3cncc3C)CC2)cc1OC CHEMBL583368 Ki 2.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C(C)C)ccc1OCCN1CCN(C)CC1 CHEMBL5094369 IC50 2.6 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCOCC1 CHEMBL5084485 IC50 2.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCCN(C)C CHEMBL5079181 IC50 2.7 nM
COc1ccc(N(C(=S)NCCCn2cncc2C)C(C)C)cc1OC CHEMBL4464130 IC50 2.8 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5081843 IC50 2.8 nM
Cc1nn(C)c2ccc(N(Cc3ccc(F)cc3)C(=O)NCCCn3cncc3C)cc12 CHEMBL5266206 IC50 3.0 nM
COc1ccc(C2C(=O)NC(=O)N2c2ccc3[nH]cnc3c2)cc1O CHEMBL3677287 IC50 3.08 nM
COc1cc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCN(C)CC1 CHEMBL5076836 IC50 3.2 nM
Cc1n[nH]c2cc(N(C(=O)NCCCn3cncc3C)C3CCCCC3)ccc12 CHEMBL5282127 IC50 3.2 nM
COc1ccc(N(Cc2cccc(F)c2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4539841 IC50 3.4 nM
COc1cc(N(CC2CCCC2)C(=O)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5088413 IC50 3.4 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5088100 IC50 3.4 nM
Cc1nn(C)c2cc(N(CC3CCCC3)C(=O)NCCCn3cncc3C)ccc12 CHEMBL5289328 IC50 3.4 nM
COc1ccc(N(Cc2cccc(Cl)c2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4586501 IC50 3.5 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCN(C)CC1 CHEMBL5092800 IC50 3.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(CCOCCN)CC1 CHEMBL4208618 IC50 3.6 nM
COc1ccc(N(CCCCc2ccnc(N)c2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4547037 IC50 3.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5088872 IC50 3.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN(C)C CHEMBL4070663 IC50 3.7 nM
CCCOc1ccc(C2C(=O)NC(=O)N2c2ccc3[nH]cnc3c2)cc1 CHEMBL3677285 Ki 3.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN1CCN(CCN)CC1 CHEMBL4212160 IC50 3.8 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCc1ccnc(N)c1 CHEMBL5089539 IC50 3.8 nM
COc1cc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCNCC1 CHEMBL5092266 IC50 3.8 nM
COc1ccc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4448303 IC50 3.9 nM
COc1cc(N(C(=O)NCCCn2cncc2C)c2ccccc2)ccc1OCCN1CCNCC1 CHEMBL5087075 IC50 3.9 nM
COc1cc(N(C(=O)NCc2ccc3[nH]cnc3c2)C2CCCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5076908 IC50 4.0 nM
COc1ccc(N(CC2CCCC2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4445143 IC50 4.1 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc(-c2ccccc2)cc1 CHEMBL3677288 Ki 4.13 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5079213 IC50 4.3 nM
COC1=CC(=O)N(c2ccc3nc[nH]c3c2)C1c1ccc(N2CCS(=O)(=O)CC2)cc1 CHEMBL3674614 Ki 4.4 nM
COc1cc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)ccc1OCCN1CCOCC1 CHEMBL5079847 IC50 4.4 nM
Cc1nn(C)c2ccc(N(C(=O)NCCCn3cncc3C)C3CCCCC3)cc12 CHEMBL5273104 IC50 4.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL4097599 IC50 4.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)NC1CCN(CCN)CC1 CHEMBL4205777 IC50 4.5 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)cc1OC CHEMBL4549443 IC50 4.5 nM
O=C1C=C(N2CCCCC2)C(c2ccc(N3CCOCC3)cc2)N1c1ccc2nc[nH]c2c1 CHEMBL3674615 Ki 4.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC1CCN(C)CC1 CHEMBL4093071 IC50 4.6 nM
COc1ccc(N(Cc2ccccc2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4459792 IC50 4.6 nM
COc1ccc(N(C(=S)NCCCn2cncc2C)C2CCCCC2)cc1OC CHEMBL4462968 IC50 4.7 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5093267 IC50 4.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCNCC1 CHEMBL4099813 IC50 4.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCN(CCO)CC1 CHEMBL4216611 IC50 4.8 nM
CCN(C(=O)NCCCn1cncc1C)c1ccc(OCCN2CCNCC2)c(OC)c1 CHEMBL5082895 IC50 4.8 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5078420 IC50 5.0 nM
COc1ccc(N(Cc2ccc(Cl)cc2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4590359 IC50 5.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN CHEMBL4082916 IC50 5.3 nM
Cc1nn(C)c2cc(N(C(=O)NCCCn3cncc3C)C3CCCCC3)ccc12 CHEMBL5288463 IC50 5.3 nM
COc1ccc(N(Cc2cccnc2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4472311 IC50 5.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCc1ccnc(N)c1 CHEMBL4074799 IC50 5.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC(=O)NC1CCNCC1 CHEMBL4205893 IC50 5.5 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C(C)C)ccc1OCCN1CCNCC1 CHEMBL5093456 IC50 5.5 nM
COc1ccc(N(Cc2ccncc2)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4459555 IC50 5.6 nM
Cc1nn(C)c2ccc(NC(=O)NCCCn3cncc3C)cc12 CHEMBL5291411 IC50 5.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCNc1ncccn1 CHEMBL4075925 IC50 5.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCNCC1C CHEMBL4202790 IC50 5.8 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc2nsnc2c1 CHEMBL3677280 Ki 6.07 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)cc1OC CHEMBL4589039 IC50 6.1 nM
COc1ccc(N(C(=S)NCCCn2cncc2C)C2CCN(C)CC2)cc1OC CHEMBL5069682 IC50 6.1 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCc1ccc(C2CCNCC2)cc1 CHEMBL4213886 IC50 6.2 nM
COc1ccc(N(CC2CCCC2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4446821 IC50 6.2 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OC CHEMBL566563 Ki 6.3 nM
Cc1cncn1CCCNC(=S)Nc1ccc(/C=C/C(=O)N2CCN(CCN)CC2)cc1 CHEMBL4127764 IC50 6.4 nM
O=C1NC(=S)C(c2ccc(Br)cc2F)N1c1ccc2nc[nH]c2c1 CHEMBL3677297 Ki 6.49 nM
COc1ccc(N(C(=S)NCCCn2cncc2C)C2CCCC2)cc1OC CHEMBL4582369 IC50 6.5 nM
COc1ccc(N(CC(C)C)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4520303 IC50 6.8 nM
CNCCCOc1ccc(NC(=S)NCCCn2cncc2C)cc1OC CHEMBL4088456 IC50 6.9 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5078932 IC50 6.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCC(=O)N1CCNCC1 CHEMBL4206718 IC50 7.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCC1CCNCC1 CHEMBL4073599 IC50 7.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(C)CC1 CHEMBL4071297 IC50 7.3 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCC1CCNCC1 CHEMBL4130158 IC50 7.3 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C(C)C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5072773 IC50 7.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(CCO)CC1 CHEMBL4204419 IC50 7.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(CCN)CC1 CHEMBL4213750 IC50 7.5 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCN(Cc3ccccc3)CC2)cc1OC CHEMBL4448862 IC50 7.5 nM
COc1ccc(N(CC(C)C)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4578714 IC50 7.6 nM
COc1cc(C2(C(=O)NCCCn3cncc3C)CC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5079568 IC50 7.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCc1ccc(N)cc1 CHEMBL4099260 IC50 7.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC(=O)N1CCNCC1 CHEMBL4206893 IC50 7.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCC1CCNCC1 CHEMBL4082802 IC50 7.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)N1CCN(CCN)CC1 CHEMBL4216476 IC50 7.8 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCN CHEMBL4127037 IC50 7.9 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCCC1CCNCC1 CHEMBL4130012 IC50 7.9 nM
Cc1cncn1CCCNC(=S)Nc1ccc(OCC(=O)NC2CCN(CCN)CC2)cc1 CHEMBL4130218 IC50 7.9 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCCCN(C)C CHEMBL5082884 IC50 7.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCN(C)CC1 CHEMBL4062645 IC50 8.2 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCNCC2)cc1OC CHEMBL4471709 IC50 8.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccc(N)cc1 CHEMBL4084521 IC50 8.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1Oc1ccc(N2CCNCC2)cc1 CHEMBL4215483 IC50 8.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCN(CCN)CC1 CHEMBL4217140 IC50 8.6 nM
COc1ccc(N(C(=S)NCCCn2cncc2C)C2CCC2)cc1OC CHEMBL4434757 IC50 8.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCN(C)C CHEMBL5077722 IC50 8.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(NCCO)c1 CHEMBL4203546 IC50 8.7 nM
COc1ccc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4567619 IC50 8.7 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCCN CHEMBL4128529 IC50 8.8 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCC1CCNCC1 CHEMBL4128801 IC50 8.8 nM
CCN(C(=S)NCCCn1cncc1C)c1ccc(OC)c(OC)c1 CHEMBL4440547 IC50 8.8 nM
COc1cc(N(C)C(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5079317 IC50 8.9 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCN1CCOCC1 CHEMBL5091269 IC50 8.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCc1ccc(N)cc1 CHEMBL4062842 IC50 9.0 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCN CHEMBL4129900 IC50 9.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC1CCN(CCO)CC1 CHEMBL4215626 IC50 9.0 nM
COc1cc(N(C(=O)NCc2ccc3[nH]cnc3c2)C2CCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5083460 IC50 9.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccncc1 CHEMBL4093243 IC50 9.1 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCOCC1 CHEMBL4100758 IC50 9.2 nM
COc1cc(N(C)C(=O)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5094798 IC50 9.2 nM
COc1cc(N(C(=O)NCCCn2cncc2C)c2ccccc2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5093282 IC50 9.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1Oc1ccc(C2=CCNCC2)cc1 CHEMBL4218344 IC50 9.4 nM
COc1cc(N(Cc2cccnc2)C(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5079535 IC50 9.5 nM
Cc1nn(C)c2cc(N(C(=O)NCCCn3cncc3C)C3CCN(C)CC3)ccc12 CHEMBL5267466 IC50 9.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1Oc1ccc(C2CCNCC2)cc1 CHEMBL4214577 IC50 9.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CC(C)NC(C)C1 CHEMBL4213555 IC50 9.9 nM
COc1cc(N(C(=O)NCc2ccc3[nH]cnc3c2)C2CCN(C)CC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5081502 IC50 9.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)NC1CCNCC1 CHEMBL4205854 IC50 10.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC1CCN(CCN)CC1 CHEMBL4207248 IC50 10.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCc1ccnc(N)c1 CHEMBL4074222 IC50 10.7 nM
COc1cc(C2(C(=O)NCCCn3cncc3C)CCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5086703 IC50 10.9 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCN1CCN(C)CC1 CHEMBL5090689 IC50 10.9 nM
COc1ccc(N(Cc2ccncc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4464265 IC50 11.0 nM
CCN(C(=S)NCCCn1cncc1C)c1ccc(OCCCCc2ccnc(N)c2)c(OC)c1 CHEMBL5085678 IC50 11.0 nM
Cc1n[nH]c2cc(N(Cc3ccc(F)cc3)C(=O)NCCCn3cncc3C)ccc12 CHEMBL5269831 IC50 11.1 nM
Cc1cncn1CCCNC(=S)Nc1ccc(/C=C/C(=O)NC2CCN(CCN)CC2)cc1 CHEMBL4126533 IC50 11.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN1CCNCC1 CHEMBL4081803 IC50 11.4 nM
Cc1cncn1CCCNC(=S)Nc1ccc(OCC(=O)N2CCNCC2)cc1 CHEMBL4130284 IC50 11.4 nM
Cc1nn(CCCCc2ccnc(N)c2)c2ccc(NC(=O)NCCCn3cncc3C)cc12 CHEMBL5277577 IC50 11.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCc1ccc(N2CCNCC2)cc1 CHEMBL4206681 IC50 11.5 nM
Cc1cncn1CCCn1c(=S)[nH]c2ccccc2c1=O CHEMBL3703751 Ki 11.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN1CCN(C)CC1 CHEMBL4098332 IC50 11.7 nM
O=C1CC(=O)N(c2ccc3nc[nH]c3c2)C1c1ccc(N2CCOCC2)cc1 CHEMBL3674616 Ki 11.9 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCCN(C)C CHEMBL5090870 IC50 11.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1Oc1ccc(N2CCN(CCN)CC2)cc1 CHEMBL4212913 IC50 12.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(c2ncccn2)CC1 CHEMBL4215098 IC50 12.0 nM
COc1cc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)ccc1OCCCN1CCCCC1 CHEMBL5193156 IC50 12.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCC1CCN(C)CC1 CHEMBL4102431 IC50 12.3 nM
COc1ccc(N(C)C(=S)NCCCn2cncc2C)cc1OC CHEMBL4586829 IC50 12.4 nM
O=C1OC[C@H](c2ccc(N3CCN(c4ccccc4)CC3)cc2)N1c1ccc2nc[nH]c2c1 CHEMBL3659481 Ki 12.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCOCC1 CHEMBL4062616 IC50 12.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCCCC1 CHEMBL4090828 IC50 12.5 nM
COc1ccc(N(Cc2ccc(Cl)cc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4520053 IC50 12.5 nM
COc1cc(N(C(=O)NCc2ccc3[nH]cnc3c2)C(C)C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5084759 IC50 12.6 nM
COc1cc(N(C(=O)NCc2ccc3[nH]cnc3c2)C2CCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5082748 IC50 12.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(Cc2ccccc2)CC1 CHEMBL4209874 IC50 12.7 nM
COc1cc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)ccc1OCCCCN(C)C CHEMBL5083871 IC50 12.8 nM
Cc1cncn1CCCNC(=S)Nc1ccc(OCC(=O)NC2CCNCC2)cc1 CHEMBL4127015 IC50 12.9 nM
COc1ccc(N(Cc2cccc(Cl)c2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4475906 IC50 12.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN(C)C CHEMBL4097231 IC50 13.0 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCN1CCN(C)CC1 CHEMBL5072886 IC50 13.0 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCN1CCNCC1 CHEMBL5081811 IC50 13.2 nM
COc1ccc(N(Cc2ccccc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4452351 IC50 13.3 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCN(C)C CHEMBL5091456 IC50 13.3 nM
Cc1nn(C)c2ccc(N(CC3CCCC3)C(=O)NCCCn3cncc3C)cc12 CHEMBL5281584 IC50 13.3 nM
Cc1nn(C)c2ccc(N(Cc3cccnc3)C(=O)NCCCn3cncc3C)cc12 CHEMBL5277759 IC50 13.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN1CCCCC1 CHEMBL4063751 IC50 13.4 nM
CNc1cc(CCCCOc2ccc(NC(=S)NCCCn3cncc3C)cc2OC)ccn1 CHEMBL4208430 IC50 13.4 nM
COc1cc(N(C)C(=O)NCCCn2cncc2C)ccc1OCCN1CCNCC1 CHEMBL5069805 IC50 13.4 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc2c(c1)OCCO2 CHEMBL3677293 Ki 13.6 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCN(Cc3ccc(F)cc3)CC2)cc1OC CHEMBL4579239 IC50 13.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN CHEMBL4100893 IC50 13.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC1CCNCC1 CHEMBL4090608 IC50 13.8 nM
O=C1CC(=O)N(c2ccc3nc[nH]c3c2)C1c1cc(F)cc(F)c1F CHEMBL3674617 Ki 13.9 nM
Cc1n[nH]c2ccc(N(Cc3ccc(F)cc3)C(=O)NCCCn3cncc3C)cc12 CHEMBL5289956 IC50 14.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN1CCOCC1 CHEMBL4085595 IC50 14.1 nM
CCN(C(=O)NCCCn1cncc1C)c1ccc(OCCCCc2ccnc(N)c2)c(OC)c1 CHEMBL5077440 IC50 14.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCc1ccncc1 CHEMBL4063693 IC50 14.4 nM
Cc1n[nH]c2cc(N(CC3CCCC3)C(=O)NCCCn3cncc3C)ccc12 CHEMBL5287602 IC50 14.5 nM
COc1cc(C(C)(C)C(=O)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5073527 IC50 14.6 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCCN1CCNCC1 CHEMBL4127544 IC50 15.0 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCc1ccnc(N)c1 CHEMBL4130156 IC50 15.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)N1CCNCC1 CHEMBL4213636 IC50 15.0 nM
COc1ccc(N(CCN2CCNCC2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4539950 IC50 15.0 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 CHEMBL5083668 IC50 15.0 nM
COc1cc(N(C)C(=O)NCCCn2cncc2C)ccc1OCCN1CCOCC1 CHEMBL5092834 IC50 15.1 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCCc1ncccn1 CHEMBL4129225 IC50 15.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cc(N)nc(N)c1 CHEMBL4093854 IC50 15.3 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCCN(C)C CHEMBL5078500 IC50 15.5 nM
Cc1cncn1CCCNC(=O)N(Cc1ccc(F)cc1)c1ccc2c(C)n(C)nc2c1 CHEMBL5276913 IC50 15.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCNC(=O)C1CCNCC1 CHEMBL4207817 IC50 15.7 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCN1CCNCC1 CHEMBL4128944 IC50 15.8 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCCc1ccnc(N)c1 CHEMBL4127824 IC50 15.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1Oc1ccc(N2CCN(CCO)CC2)cc1 CHEMBL4204845 IC50 16.1 nM
CNCCCCOc1ccc(NC(=S)NCCCn2cncc2C)cc1OC CHEMBL4089521 IC50 16.2 nM
Cc1cncn1CCCNC(=S)Nc1ccc(C(=O)NC2CCN(CCN)CC2)cc1 CHEMBL4129008 IC50 16.2 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCN(c3ccccc3)CC2)cc1OC CHEMBL4443747 IC50 16.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCc1cc(N)nc(N)c1 CHEMBL4066278 IC50 16.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCC(=O)NC1CCNCC1 CHEMBL4202728 IC50 16.7 nM
Cn1cnnc1C1CCN(c2ncccc2-c2ccc(F)nc2)CC1 CHEMBL4462495 IC50 16.7 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCc1ccnc(N)c1 CHEMBL5074856 IC50 16.9 nM
Cc1cncn1CCCN1Cc2c(sc3c2CCCC3)NC1=S CHEMBL574500 Ki 17.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1Oc1ccc(N2CCN(C)CC2)cc1 CHEMBL4216695 IC50 17.0 nM
COc1ccc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)cc1OC CHEMBL5190683 IC50 17.0 nM
COc1cc(N(CC2CCCC2)C(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5092017 IC50 17.1 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 CHEMBL3703753 Ki 17.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(CCOCCO)CC1 CHEMBL4218341 IC50 17.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCNc1ncc(F)cn1 CHEMBL4076559 IC50 17.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCNc1ncccn1 CHEMBL4059704 IC50 17.5 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C(C)C)cc1OC CHEMBL4469263 IC50 17.5 nM
COc1ccc(N(Cc2ccnc(N)c2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4436441 IC50 17.6 nM
Cc1ccc(C2C(=S)NC(=O)N2c2ccc3[nH]cnc3c2)c(F)c1F CHEMBL3677298 Ki 17.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)NC1CCN(CCO)CC1 CHEMBL4214390 IC50 17.7 nM
Cc1cncn1CCCN1Cc2ccccc2NC1=S CHEMBL567646 Ki 18.0 nM
COc1cc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)ccc1OCCCc1ccccn1 CHEMBL5181839 IC50 18.0 nM
Cc1n[nH]c2ccc(N(CC3CCCC3)C(=O)NCCCn3cncc3C)cc12 CHEMBL5286870 IC50 18.2 nM
COc1cc(N(Cc2ccc(F)cc2)C(=O)NCCCn2cncc2C)ccc1OCCN(C)C CHEMBL5084322 IC50 18.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cnc(N)nc1 CHEMBL4092890 IC50 18.4 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCN1CCNCC1 CHEMBL4126320 IC50 18.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCNc1ncc(F)cn1 CHEMBL4086721 IC50 18.5 nM
Cc1cncn1CCCNC(=S)Nc1ccc(OCCN2CCNCC2)cc1 CHEMBL4126591 IC50 18.7 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCN1CCOCC1 CHEMBL5077702 IC50 18.7 nM
O=C1CC(=O)N(c2ccc3nc[nH]c3c2)C1c1cccc(F)c1F CHEMBL3674613 Ki 18.8 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc(Cc3ccccc3)cc2c1=O CHEMBL3640026 Ki 18.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(NC(C)=O)c1 CHEMBL4070421 IC50 19.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC(N)=O CHEMBL4202896 IC50 19.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cccc(N)n1 CHEMBL4074894 IC50 19.3 nM
Cc1cncn1CCCNC(=S)Nc1ccc(/C=C/C(=O)N2CCNCC2)cc1 CHEMBL4127604 IC50 19.4 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCCC2)cc1OC CHEMBL4451831 IC50 19.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cccnc1 CHEMBL4065599 IC50 19.8 nM
Cc1cncn1CCCN1Cc2cc(Cc3ccccc3)sc2NC1=S CHEMBL565265 Ki 20.0 nM
COc1cc(N(C(=O)NCc2ccc3[nH]cnc3c2)C2CCNCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5085825 IC50 20.0 nM
COc1cc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)ccc1OCCCN1CCOCC1 CHEMBL5202172 IC50 20.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCC1CCN(C)CC1 CHEMBL4077135 IC50 20.2 nM
Cc1nn(CCCCc2ccnc(N)c2)c2cc(NC(=O)NCCCn3cncc3C)ccc12 CHEMBL5268024 IC50 20.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCc1cnc(N)nc1 CHEMBL4063517 IC50 20.5 nM
COc1ccc(N(Cc2cccc(F)c2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4585964 IC50 20.5 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCC1CCN(C)CC1 CHEMBL4126747 IC50 20.6 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C(C)C)ccc1OCCN1CCOCC1 CHEMBL5083823 IC50 20.8 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc(-c3ccccc3)cc2c1=O CHEMBL3703757 Ki 21.1 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cncnc1 CHEMBL4075609 IC50 21.3 nM
COc1cc(N(Cc2ccccc2)C(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5077524 IC50 21.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(c2ccccc2)CC1 CHEMBL4203358 IC50 21.6 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccccc1Cl CHEMBL3677291 Ki 21.7 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC3 CHEMBL3703758 Ki 21.7 nM
CNCCCCOc1cc(NC(=S)NCCCn2cncc2C)ccc1OC CHEMBL4129751 IC50 22.0 nM
Cc1cncn1CCCNC(=O)N(Cc1ccc(F)cc1)c1ccc2nn(C)c(C)c2c1 CHEMBL5277817 IC50 22.7 nM
COc1ccc(C2(C(=O)NCCCn3cncc3C)CCCC2)cc1OC CHEMBL4454399 IC50 22.9 nM
COc1ccc(SCc2nnc(-c3ccc4[nH]cnc4c3)s2)cc1OC CHEMBL2418779 Ki 23.0 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCN(Cc3cccnc3)CC2)cc1OC CHEMBL4438809 IC50 23.3 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCc1ccncc1 CHEMBL4076975 IC50 23.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCN1CCN(CCO)CC1 CHEMBL4209292 IC50 23.5 nM
COc1ccc(N(Cc2ccc(N)nc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4474239 IC50 23.5 nM
COc1cc(C2(C(=O)NCCCn3cncc3C)CCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5094666 IC50 23.8 nM
COc1cc(C(C)(C)C(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5091813 IC50 24.0 nM
Cc1sc2[nH]c(=S)n(CCCn3cncc3C)c(=O)c2c1C CHEMBL3703755 Ki 24.1 nM
COc1ccc(C2(C(=O)NCCCn3cncc3C)CC2)cc1OC CHEMBL4470465 IC50 24.3 nM
CCCOc1ccc([C@H]2CNC(=O)N2c2ccc3[nH]cnc3c2)cc1 CHEMBL3659477 K 24.6 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCCCC1 CHEMBL4065376 IC50 24.7 nM
Cc1cncn1CCCNC(=S)Nc1ccc(OCCCCc2ccnc(N)c2)cc1 CHEMBL4127982 IC50 24.7 nM
CCc1cc2c(=O)n(CCCn3cncc3C)c(=S)[nH]c2s1 CHEMBL3703754 Ki 25.0 nM
COc1ccc(N(CCN2CCOCC2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4589697 IC50 25.0 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCCC3 CHEMBL3703760 Ki 25.1 nM
Cc1n[nH]c2cc(N(Cc3cccnc3)C(=O)NCCCn3cncc3C)ccc12 CHEMBL5268178 IC50 25.4 nM
COc1ccc(N(C(=S)NCCCn2cncc2C)C2CC2)cc1OC CHEMBL4578087 IC50 25.6 nM
Cc1cncn1CCCNC(=S)Nc1ccc(/C=C/C(=O)NC2CCNCC2)cc1 CHEMBL4126383 IC50 26.0 nM
CCN(C(=O)NCc1ccc2[nH]cnc2c1)c1ccc(OCCCCc2ccnc(N)c2)c(OC)c1 CHEMBL5093392 IC50 26.0 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCc1ccnc(N)c1 CHEMBL4128798 IC50 26.4 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCC2)cc1OC CHEMBL4586610 IC50 26.5 nM
CNCCCOc1cc(NC(=S)NCCCn2cncc2C)ccc1OC CHEMBL4126468 IC50 26.8 nM
CCN(C(=O)NCCCn1cncc1C)c1ccc(OC)c(OC)c1 CHEMBL4476133 IC50 27.0 nM
COc1cc(NC(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5080418 IC50 27.1 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCCCC3 CHEMBL3703761 Ki 28.5 nM
CCCOc1ccc([C@@H]2CNC(=O)N2c2ccc3nc[nH]c3c2)cc1 CHEMBL3659476 IC50 29.0 nM
COc1ccc(NC(=S)NCCCn2ccnc2)cc1OC CHEMBL201747 IC50 29.0 nM
Cc1cncn1CCCNC(=O)N(Cc1ccc(F)cc1)c1ccc2cnn(C)c2c1 CHEMBL5283072 IC50 29.0 nM
Cc1nn(CCN2CCN(C)CC2)c2ccc(NC(=O)NCCCn3cncc3C)cc12 CHEMBL5288578 IC50 29.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN CHEMBL4093175 IC50 30.2 nM
COc1ccc(N(Cc2ccc(F)nc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4445955 IC50 30.6 nM
CCc1c(C)sc2[nH]c(=S)n(CCCn3cncc3C)c(=O)c12 CHEMBL3703756 Ki 30.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(C(C)=O)CC1 CHEMBL4207627 IC50 30.8 nM
Cc1cncn1CCCNC(=O)N(CC1CCCCC1)c1ccc2nn(C)c(C)c2c1 CHEMBL5268584 IC50 31.7 nM
COc1ccc(N(Cc2ccc(Cl)nc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4469107 IC50 32.5 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCN(C)CC2)ccc1OCCN1CCOCC1 CHEMBL5073074 IC50 33.0 nM
CCCOc1ccc([C@H]2COC(=O)N2c2ccc3nc[nH]c3c2)cc1 CHEMBL3659480 Ki 33.6 nM
Cc1cncn1CCCN/C(=C\[N+](=O)[O-])Nc1ccc(C(F)(F)F)cc1 CHEMBL578153 Ki 34.0 nM
COc1cc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)ccc1OCCCN(C)C CHEMBL5085635 IC50 34.1 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1cc(F)ccc1Br CHEMBL3677284 Ki 34.8 nM
Cc1ccc(O)c(C2C(=O)NC(=O)N2c2ccc3[nH]cnc3c2)c1 CHEMBL3677282 IC50 34.9 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCC(=O)N(C)C CHEMBL4202459 IC50 35.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCc1cncnc1 CHEMBL4101582 IC50 35.5 nM
COc1cc(N(C)C(=O)NCc2ccc3[nH]cnc3c2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5077771 IC50 35.7 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1cccc(Cl)c1 CHEMBL3677289 Ki 36.0 nM
COc1ccc(N(CCc2ccnc(N)c2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4560536 IC50 36.9 nM
COc1ccc(C2(C(=O)NCCCn3cncc3C)CCC2)cc1OC CHEMBL4519348 IC50 37.1 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CC2)cc1OC CHEMBL4524440 IC50 38.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN(C)C CHEMBL4065832 IC50 38.6 nM
CNCCOc1ccc(NC(=S)NCCCn2cncc2C)cc1OC CHEMBL4061029 IC50 38.7 nM
Cc1cncn1CCCN1Cc2c(sc3c2CCCCCC3)NC1=S CHEMBL567842 Ki 39.0 nM
COc1ccc(C(Cc2ccccc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4470900 IC50 39.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCNc1ncccn1 CHEMBL4081649 IC50 39.4 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCCCN(C)C CHEMBL5084891 IC50 39.7 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(c2ncc(F)cn2)CC1 CHEMBL4203427 IC50 40.3 nM
O=C1NC[C@H](c2ccc(-c3ccccc3)cc2)N1c1ccc2nc[nH]c2c1 CHEMBL3985410 Ki 40.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCNC(C)=O CHEMBL4071094 IC50 40.8 nM
COc1ccc(C2(C(=S)NCCCn3cnc(C)c3)CC2)cc1OC CHEMBL578798 Ki 41.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCNC(=N)N CHEMBL4102625 IC50 41.2 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccccc1 CHEMBL3677281 Ki 41.3 nM
Cc1cncn1CCCN/C(=C\[N+](=O)[O-])Nc1cccc2ccccc12 CHEMBL565907 Ki 42.0 nM
COc1cc(N(C(=O)NCCCn2cncc2C)C2CCCCC2)ccc1OCCCCN(C)C CHEMBL5078637 IC50 42.0 nM
COc1cc(C2(C(=O)NCc3ccc4[nH]cnc4c3)CC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5072318 IC50 42.2 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc(Cl)cc1 CHEMBL3677290 Ki 42.8 nM
Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC(C)C3 CHEMBL3703759 Ki 43.5 nM
Cc1cncn1CCCNC(=O)N(Cc1cccnc1)c1ccc2c(C)n(C)nc2c1 CHEMBL5274513 IC50 43.8 nM
Cc1cncn1CCCN/C(=C\[N+](=O)[O-])NC1CCCCC1 CHEMBL574357 Ki 44.0 nM
O=C1NC(=S)C(c2ccc(Cl)cc2)N1c1ccc2[nH]cnc2c1 CHEMBL3677295 Ki 45.9 nM
COc1ccc(NC(=S)NCCCn2cncc2C)cc1OCCCCN(C)C CHEMBL4127700 IC50 46.8 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)N1CCN(CCO)CC1 CHEMBL4212704 IC50 48.7 nM
Cc1cncn1CCCN/C(=C\[N+](=O)[O-])Nc1ccc(Cl)cc1 CHEMBL567406 Ki 51.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCC(=O)N(C)C CHEMBL4209873 IC50 51.0 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1cc(C(F)(F)F)ccc1F CHEMBL3677283 Ki 51.6 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCCN(C)C CHEMBL5076741 IC50 51.9 nM
COc1ccc([C@H]2c3ccccc3C(=O)N2c2ccc3nc[nH]c3c2)cc1OC CHEMBL3659482 Ki 53.5 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCC(N)=O CHEMBL4207782 IC50 53.8 nM
Cc1n[nH]c2cc(N(C(=O)NCCCn3cncc3C)C3CCN(C)CC3)ccc12 CHEMBL5281802 IC50 53.8 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)C2CCN(C(C)=O)CC2)cc1OC CHEMBL4561441 IC50 53.9 nM
Cc1cncn1CCCNC(=S)Nc1ccc(OCC(=O)NCc2ccnc(N)c2)cc1 CHEMBL4128856 IC50 56.5 nM
N#Cc1cccc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)c1 CHEMBL5195495 IC50 57.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)OCCO2 CHEMBL2392817 IC50 58.0 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc(F)cc1 CHEMBL3677292 Ki 58.5 nM
CCCOc1ccc([C@H]2c3ccccc3C(=O)N2c2ccc3nc[nH]c3c2)cc1 CHEMBL3659483 Ki 58.8 nM
COc1ccc(NC(=S)NCCCn2cnc(C)c2)cc1OC CHEMBL565917 Ki 60.0 nM
COc1cc(N/C(=N/C#N)NCCCn2cncc2C)cc(OC)c1OC CHEMBL567221 Ki 61.0 nM
CCCn1ncc2ccc(N(Cc3ccc(F)cc3)C(=O)NCCCn3cncc3C)cc21 CHEMBL5282930 IC50 62.4 nM
CCCOc1ccc(C2CNC(=O)N2c2ccc3nc[nH]c3c2)cc1 CHEMBL3659475 Ki 62.5 nM
Cc1cncn1CCCN/C(=N\C#N)Nc1ccc(-c2ccccc2)cc1 CHEMBL566321 Ki 65.0 nM
O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc(Cl)c(C(F)(F)F)c1 CHEMBL3677286 Ki 65.5 nM
Cc1nn(C)c2cc(N(Cc3cccnc3)C(=O)NCCCn3cncc3C)ccc12 CHEMBL5286536 IC50 65.9 nM
Cc1cncn1CCCNC(=O)N(Cc1ccc(F)cc1)c1ccc2cn[nH]c2c1 CHEMBL5275966 IC50 66.2 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCN(c2ncc(Cl)cn2)CC1 CHEMBL4210669 IC50 66.8 nM
Cc1cncn1CCCN/C(=C\[N+](=O)[O-])Nc1ccc2c(c1)OCCO2 CHEMBL565908 Ki 67.0 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)c2ncco2)cc1OC CHEMBL4559062 IC50 69.6 nM
Cc1nn(CCN2CCN(C)CC2)c2cc(NC(=O)NCCCn3cncc3C)ccc12 CHEMBL5281059 IC50 71.2 nM
CCCOc1ccc(C2CNC(=O)N2c2ccn3ccnc3c2)cc1 CHEMBL3659478 Ki 75.0 nM
COc1ccc(C(C)(C)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4533601 IC50 77.3 nM
COc1ccc(C2(C(=O)NCCCn3cncc3C)CCCCC2)cc1OC CHEMBL4466671 IC50 77.5 nM
COc1ccc(N(C)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4554520 IC50 78.7 nM
Cc1sc2[nH]c(=S)n(CCCn3cncc3C)c(=O)c2c1-c1ccccc1 CHEMBL3703762 Ki 79.7 nM
COc1ccc(S(=O)(=O)Cc2nnc(-c3ccc4[nH]cnc4c3)s2)cc1OC CHEMBL2418780 Ki 80.0 nM
CCN1CCC(N(C(=O)NCCCn2cncc2C)c2ccc(OC)c(OC)c2)CC1 CHEMBL4570337 IC50 81.0 nM
COc1ccc(C(Cc2cccnc2)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4448966 IC50 81.6 nM
Cc1ccc(N/C(=N/C#N)NCCCn2cncc2C)cc1C CHEMBL567407 Ki 82.0 nM
Cc1sc2c(c1-c1ccccc1)CN(CCCn1cncc1C)C(=S)N2 CHEMBL578632 Ki 83.0 nM
O=C1NC(=S)C(c2ccc(F)c(F)c2F)N1c1ccc2nc[nH]c2c1 CHEMBL3677296 Ki 85.3 nM
Cc1nn(C)c2cc(NC(=O)NCCCn3cncc3C)ccc12 CHEMBL5276086 IC50 87.4 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(N)=O CHEMBL4212129 IC50 89.7 nM
COc1ccc(C2(C(=S)NCCCn3ccnc3)CC2)cc1OC CHEMBL203195 Ki 90.0 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)c2ccccc2)cc1OC CHEMBL4441084 IC50 93.0 nM
Cc1ccc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)cc1C CHEMBL5197396 IC50 98.0 nM
COc1ccc(N(C(=O)NCCCn2cncc2C)c2nccs2)cc1OC CHEMBL4577303 IC50 98.8 nM
COc1cccc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)c1 CHEMBL5207620 IC50 100.0 nM
COc1ccc(CCn2cc(-c3ccc4[nH]cnc4c3)nn2)cc1 CHEMBL2418782 Ki 106.0 nM
COc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)cc1OC CHEMBL2418773 Ki 107.0 nM
Cc1n[nH]c2ccc(NC(=O)NCCCn3cncc3C)cc12 CHEMBL5275094 IC50 107.0 nM
Nc1nnc(-c2ccc3c(c2)ncn3Cc2ccc(Cl)c(F)c2)s1 CHEMBL5194983 IC50 108.0 nM
COc1cc(NC(=O)NCCCn2cncc2C)ccc1OCCN(C)C CHEMBL5080708 IC50 109.0 nM
Nc1nnc(-c2ccc3c(c2)ncn3Cc2ccc(F)c(F)c2)s1 CHEMBL5202004 IC50 111.0 nM
COc1ccc(C(C)C(=O)NCCCn2cncc2C)cc1OC CHEMBL4466213 IC50 112.0 nM
Cc1csc2c(=O)n(CCCn3cncc3C)c(=S)[nH]c12 CHEMBL3703752 Ki 113.0 nM
COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCC(=O)N(C)C CHEMBL4214145 IC50 117.0 nM
Cc1cn(CCCNc2ccccc2-c2ccc(F)cc2)cn1 CHEMBL4093740 IC50 118.0 nM
Nc1nnc(-c2ccc3c(c2)ncn3Cc2ccc(C(F)(F)F)cc2)s1 CHEMBL5178150 IC50 118.0 nM
Cc1cncn1CCCn1c(=O)[nH]c2ccccc2c1=O CHEMBL2392800 IC50 123.0 nM
Cc1cncn1CCCN/C(=N\C#N)Nc1ccc2c(c1)OCCO2 CHEMBL574356 Ki 130.0 nM
COc1ccc(CCn2cc(-c3ccc4[nH]cnc4c3)nn2)cc1OC CHEMBL2418784 Ki 139.0 nM
Cc1n[nH]c2cc(NC(=O)NCCCn3cncc3C)ccc12 CHEMBL5266892 IC50 141.0 nM
O=C1NCC(c2ccc(-c3ccccc3)cc2)N1c1ccn2ccnc2c1 CHEMBL3659479 Ki 149.0 nM
Nc1nnc(-c2ccc3c(c2)ncn3Cc2ccc(F)cc2)s1 CHEMBL5204178 IC50 154.0 nM
COc1cccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)c1OC CHEMBL2418775 Ki 157.0 nM
Cc1cncn1CCCNC(=S)Nc1nccc2ccccc12 CHEMBL2392794 IC50 158.0 nM
O=C1NC(=O)C2(Cc3ccccc3C2)N1c1ccc2[nH]cnc2c1 CHEMBL3677294 Ki 159.0 nM
COc1ccc(Cn2cnc3cc(-c4nnc(N)s4)ccc32)cc1 CHEMBL5186970 IC50 160.0 nM
COc1ccc(NC(=O)NCCCn2cncc2C)cc1OC CHEMBL4475055 IC50 162.0 nM
c1nc2cc(-c3nnc(CCc4ccc5c(c4)OCO5)s3)ccc2[nH]1 CHEMBL2418776 Ki 167.0 nM
COc1ccc(Cn2cnc3ccc(-c4nnc(N)s4)cc32)cc1OC CHEMBL5198938 IC50 170.0 nM
COc1ccc(CC(=O)NCCCn2cncc2C)cc1OC CHEMBL4587761 IC50 183.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)OCO2 CHEMBL2392810 IC50 185.0 nM
Nc1nnc(-c2ccc3[nH]cnc3c2)s1 CHEMBL5174441 IC50 190.0 nM
COc1cc(N(Cc2cccnc2)C(=O)NCCCn2cncc2C)ccc1OCCN(C)C CHEMBL5081316 IC50 193.0 nM
COc1ccc(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)cc1 CHEMBL3642571 Ki 194.0 nM
Nc1nnc(-c2ccc3c(c2)ncn3Cc2ccc3c(c2)OCO3)s1 CHEMBL5174554 IC50 199.0 nM
COc1ccc(Cn2ncc3cc(-c4nnc(N)s4)ccc32)cc1OC CHEMBL5175865 IC50 200.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCO2 CHEMBL2392814 IC50 208.0 nM
Cc1cncn1CCCNC(=O)N(Cc1cccnc1)c1ccc2nn(C)c(C)c2c1 CHEMBL5271452 IC50 210.0 nM
c1ccc(CCn2cc(-c3ccc4[nH]cnc4c3)nn2)cc1 CHEMBL2418781 Ki 211.0 nM
COc1cccc(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)c1 CHEMBL3642572 Ki 228.0 nM
Cc1cn(CCCn2c(=S)[nH]c3ccccc3c2=O)cn1 CHEMBL3703763 Ki 229.0 nM
Cc1cn(CCCN2Cc3ccccc3NC2=S)cn1 CHEMBL577061 Ki 230.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2cnn(C)c2c1 CHEMBL2392803 IC50 239.0 nM
COc1cccc(CCn2cc(-c3ccc4[nH]cnc4c3)nn2)c1 CHEMBL2418783 Ki 250.0 nM
Cc1cncn1CCCN/C(=N\C#N)Nc1ccc(Cl)c(Cl)c1 CHEMBL566320 Ki 253.0 nM
COc1cc(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)cc(OC)c1 CHEMBL3642573 Ki 271.0 nM
Cc1cn(CCCn2c(=S)[nH]c3c(C)csc3c2=O)cn1 CHEMBL3703764 Ki 285.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2ncccc2c1 CHEMBL2392778 IC50 293.0 nM
S=C1Nc2ccccc2CN1CCCn1ccnc1 CHEMBL565704 Ki 300.0 nM
O=c1c2ccccc2[nH]c(=S)n1CCCn1ccnc1 CHEMBL1490888 Ki 300.0 nM
CSc1ccc(CN(Cc2ccc(C)cc2)c2ccc3nc[nH]c3c2)cc1 CHEMBL3642570 Ki 305.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCCC4)cn1 CHEMBL3703765 Ki 307.0 nM
CSc1ccc(CN(Cc2ccccc2)c2ccc3nc[nH]c3c2)cc1 CHEMBL3642569 Ki 313.0 nM
Cc1nc2ccc(NC(=S)NCCCn3cncc3C)cc2o1 CHEMBL2392786 IC50 329.0 nM
c1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)cc1 CHEMBL2418772 Ki 333.0 nM
O=S(=O)(Cc1nnc(-c2ccc3[nH]cnc3c2)o1)c1ccccc1 CHEMBL2418800 Ki 335.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2ccccc2n1 CHEMBL2392793 IC50 337.0 nM
COc1cc(N/C(S)=N/CCCn2ccnc2)cc(OC)c1OC CHEMBL383022 Ki 340.0 nM
COc1ccc(N/C(S)=N/C[C@@H](C)Cn2ccnc2)cc1OC CHEMBL201184 Ki 340.0 nM
S=C1Nc2sc3c(c2CN1CCCn1ccnc1)CCCC3 CHEMBL578765 Ki 340.0 nM
O=c1c2c3c(sc2[nH]c(=S)n1CCCn1ccnc1)CCCC3 CHEMBL3703778 Ki 340.0 nM
Cc1ccc(CN(Cc2ccc(C)cc2)c2ccc3nc[nH]c3c2)cc1 CHEMBL3642567 Ki 346.0 nM
Cc1cn(CCCn2c(=S)[nH]c3ccsc3c2=O)cn1 CHEMBL3703776 Ki 348.0 nM
c1ccc(SCc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 CHEMBL2418799 Ki 351.0 nM
Cc1csc2c1NC(=S)N(CCCn1ccnc1)C2 CHEMBL565694 Ki 360.0 nM
Cc1csc2c(=O)n(CCCn3ccnc3)c(=S)[nH]c12 CHEMBL3703777 Ki 360.0 nM
COc1ccc2c(c1)c(C1=C(c3ccc(F)cc3)C(=O)NC1=O)cn2CCCn1ccnc1 CHEMBL5426515 IC50 360.0 nM
Cc1cncn1CCCNC(=S)Nc1cccc2ncccc12 CHEMBL2392783 IC50 375.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2cn[nH]c2c1 CHEMBL2392804 IC50 381.0 nM
COc1cccc(CCc2nnc(-c3ccc4[nH]cnc4c3)o2)c1OC CHEMBL2418803 Ki 382.0 nM
COc1ccc(C/C(S)=N/CCCn2ccnc2)cc1OC CHEMBL382268 Ki 390.0 nM
COc1ccc(C2(/C(S)=N/CCCn3ccnc3)CC2)cc1 CHEMBL383477 Ki 400.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)OCC2 CHEMBL2392813 IC50 405.0 nM
c1nc2cc(-c3nnc(CCc4ccc5c(c4)OCO5)o3)ccc2[nH]1 CHEMBL2418768 Ki 415.0 nM
CCc1cc2c(=O)n(CCCn3cnc(C)c3)c(=S)[nH]c2s1 CHEMBL3703766 Ki 417.0 nM
COc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1OC CHEMBL2418801 Ki 424.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCC(C)C4)cn1 CHEMBL3703771 Ki 430.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCO2 CHEMBL2392812 IC50 437.0 nM
Cc1cncn1CCCNC(=S)Nc1ccccn1 CHEMBL2392789 IC50 453.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2ncn(C)c2c1 CHEMBL2392807 IC50 461.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2nc[nH]c2c1 CHEMBL2392805 IC50 463.0 nM
COc1cc(C2(C(=O)NCc3ccc4[nH]cnc4c3)CCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5091080 IC50 471.0 nM
COc1cccc(CN(Cc2cccc(OC)c2)c2ccc3nc[nH]c3c2)c1 CHEMBL3642568 Ki 473.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2ocnc2c1 CHEMBL2392808 IC50 475.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)OCCC2 CHEMBL2390975 IC50 479.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCC2=O CHEMBL2392796 IC50 482.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2ncsc2c1 CHEMBL2392788 IC50 488.0 nM
COc1ccc(NC(=O)NCCCn2ccnc2)cc1OC CHEMBL201392 Ki 490.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)NCCO2 CHEMBL2392815 IC50 492.0 nM
O=[N+]([O-])/C=C(\NCCCn1ccnc1)NC1CCCCC1 CHEMBL577493 Ki 500.0 nM
COc1ccc(-c2cccc(F)c2NCCCn2cnc(C)c2)cc1OC CHEMBL4102009 IC50 500.0 nM
COc1cccc(CSc2nnc(-c3ccc4[nH]cnc4c3)[nH]2)c1 CHEMBL5188828 IC50 500.0 nM
COc1ccc(CSc2nnc(-c3ccc4[nH]cnc4c3)[nH]2)cc1OC CHEMBL5205052 IC50 500.0 nM
Cc1cncn1CCCNC(=S)Nc1cc2ccccc2cn1 CHEMBL2392791 IC50 518.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCC2O CHEMBL2392798 IC50 519.0 nM
COc1cc(F)c(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)cc1OC CHEMBL3642574 Ki 519.0 nM
O=[N+]([O-])/C=C(\NCCCn1ccnc1)Nc1cccc2ccccc12 CHEMBL565480 Ki 520.0 nM
Cc1nc2cc(NC(=S)NCCCn3cncc3C)ccc2o1 CHEMBL2392809 IC50 524.0 nM
Fc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)c(F)c1 CHEMBL2418777 Ki 536.0 nM
O=[N+]([O-])/C=C(\NCCCn1ccnc1)Nc1ccc(C(F)(F)F)cc1 CHEMBL565479 Ki 540.0 nM
O=[N+]([O-])/C=C(\NCCCn1ccnc1)Nc1ccc2c(c1)OCCO2 CHEMBL565492 Ki 540.0 nM
Cc1cncn1CCCNC(=S)Nc1cccc2cnccc12 CHEMBL2392782 IC50 546.0 nM
COc1ccc(N/C(S)=N/CCCCn2ccnc2)cc1OC CHEMBL202922 Ki 550.0 nM
Fc1c(F)c(F)c(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)c(F)c1F CHEMBL3958231 Ki 550.0 nM
COc1ccc(/N=C(\S)NCCCn2ccnc2)c(OC)c1 CHEMBL382390 Ki 560.0 nM
O=[N+]([O-])/C=C(\NCCCn1ccnc1)Nc1ccc(Cl)cc1 CHEMBL567415 Ki 570.0 nM
c1ccc2cc(CSc3nnc(-c4ccc5[nH]cnc5c4)o3)ccc2c1 CHEMBL2418793 Ki 600.0 nM
Nc1nnc(-c2ccc3[nH]ncc3c2)s1 CHEMBL5187305 IC50 600.0 nM
COc1ccc(N/C(=C/[N+](=O)[O-])NCCCn2ccnc2)cc1OC CHEMBL582920 Ki 610.0 nM
O=c1c2c3c(sc2[nH]c(=S)n1CCCn1ccnc1)CCC3 CHEMBL3703780 Ki 615.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc(Cc4ccccc4)cc3c2=O)cn1 CHEMBL3703775 Ki 616.0 nM
N#C/N=C(\NCCCn1ccnc1)Nc1ccc2c(c1)OCCO2 CHEMBL567615 Ki 620.0 nM
S=C1Nc2sc3c(c2CN1CCCn1ccnc1)CCC3 CHEMBL565695 Ki 620.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCCCCC4)cn1 CHEMBL3703773 Ki 632.0 nM
c1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 CHEMBL2418797 Ki 638.0 nM
COc1ccc(-c2c(C)cccc2NCCCn2ccnc2)cc1OC CHEMBL4081943 IC50 640.0 nM
COc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)c(OC)c1 CHEMBL2418774 Ki 645.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc(C)c(C)c3c2=O)cn1 CHEMBL3703767 Ki 682.0 nM
COc1cc(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)cc(OC)c1OC CHEMBL3974413 Ki 690.0 nM
COc1cc(C2(C(=O)NCc3ccc4[nH]cnc4c3)CCCC2)ccc1OCCCCc1ccnc(N)c1 CHEMBL5074791 IC50 691.0 nM
COc1ccc(N/C(S)=N/CCCn2ccnc2)cc1 CHEMBL201092 Ki 700.0 nM
O=C1CNC(=S)N1CCCn1ccnc1 CHEMBL201537 Ki 700.0 nM
COc1ccc(N/C(=N/C#N)NCCCn2ccnc2)cc1 CHEMBL579184 Ki 700.0 nM
COc1ccc(-c2c(C)cccc2NCCCn2cnc(C)c2)cc1OC CHEMBL4064459 IC50 700.0 nM
Fc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)o2)c(F)c1 CHEMBL2418769 Ki 702.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)ncn2C CHEMBL2392806 IC50 711.0 nM
COc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)o2)c(OC)c1 CHEMBL2418802 Ki 716.0 nM
Cc1cc(C)c(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)c(C)c1 CHEMBL3969169 Ki 740.0 nM
COc1cc(N/C(S)=N/CCCn2ccnc2)cc(OC)c1 CHEMBL383660 Ki 750.0 nM
COc1ccc(N/C(S)=N/C[C@H](C)Cn2ccnc2)cc1OC CHEMBL201139 Ki 760.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2cccnc2c1 CHEMBL2392779 IC50 768.0 nM
c1ccc(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 CHEMBL2418792 Ki 780.0 nM
Fc1ccc(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 CHEMBL3916473 Ki 780.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)C(=O)CCC2 CHEMBL2392797 IC50 788.0 nM
Cc1cn(CCCNc2cccc(C)c2-c2ccc(F)cc2)cn1 CHEMBL4101461 IC50 790.0 nM
Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)C(O)CCC2 CHEMBL2392799 IC50 812.0 nM
CC(C)c1ccc(N/C(=N/C#N)NCCCn2ccnc2)cc1 CHEMBL565716 Ki 830.0 nM
Cc1cccc(NCCCn2ccnc2)c1-c1ccc(F)cc1 CHEMBL4076098 IC50 830.0 nM
Cc1cn(CCCNc2cccc(F)c2-c2ccc(F)cc2)cn1 CHEMBL4083469 IC50 880.0 nM
CCOc1ccc(N/C(S)=N/CCCn2ccnc2)cc1 CHEMBL201039 Ki 890.0 nM
COc1ccc(-c2ccccc2NCCCn2cnc(C)c2)cc1OC CHEMBL4068882 IC50 890.0 nM
S=C1Nc2sc3c(c2CN1CCCn1ccnc1)CCCCCC3 CHEMBL574137 Ki 900.0 nM
O=c1c2c3c(sc2[nH]c(=S)n1CCCn1ccnc1)CCCCCC3 CHEMBL3703781 Ki 900.0 nM
c1ccc(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)nc1 CHEMBL3944986 Ki 910.0 nM
COc1ccc(-c2cc(C)ccc2NCCCn2cnc(C)c2)cc1OC CHEMBL4102373 IC50 940.0 nM
c1ccc(OCc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 CHEMBL2418798 Ki 941.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCCCC4)cn1 CHEMBL3703772 Ki 964.0 nM
S=C(NCCCn1ccnc1)Nc1ccc(OCc2ccccc2)cc1 CHEMBL201574 Ki 970.0 nM
Cc1cn(CCCn2c(=S)[nH]c3sc(C)c(-c4ccccc4)c3c2=O)cn1 CHEMBL3703774 Ki 971.0 nM
COc1ccc(/N=C(\S)CCCCn2ccnc2)cc1OC CHEMBL382344 Ki 990.0 nM