CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1 CHEMBL38 Ki 0.1 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cnc21 CHEMBL133725 ED30 0.11 nM
CC1(C)CCC(C)(C)c2nc(C(=O)Nc3ccc(C(=O)O)cc3)cnc21 CHEMBL432592 EC30 0.15 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL275311 EC50 0.18 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1C(C)C CHEMBL159167 Relative EC30 0.19 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)co3)cnc21 CHEMBL131925 ED30 0.21 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1C(C)(C)C CHEMBL159168 Relative EC30 0.22 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL160376 Relative EC30 0.27 nM
O=C(O)c1ccc(-c2ccc(-c3cc4c(C(F)(F)F)ccc(F)c4o3)[nH]2)cc1 CHEMBL430677 Relative EC30 0.29 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL69367 EC30 0.3 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)ccc21 CHEMBL134375 EC30 0.34 nM
Cc1ccc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL48353 Relative EC30 0.37 nM
CC1(C)CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL451835 EC50 0.6 nM
CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21 CHEMBL25202 ED30 0.67 nM
O=C(O)c1ccc(-c2ccc(-c3cc4c(Cl)ccc(Cl)c4o3)[nH]2)cc1 CHEMBL46229 Relative EC30 0.7 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2cc(F)cc(F)c2)cc(C(C)C)c1OCC(F)F CHEMBL337393 Synergy 0.8 nM
Cc1cccc2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)oc12 CHEMBL98263 Relative EC30 0.8 nM
CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)cc[n+]([O-])c3C)CC2)CC1 CHEMBL78535 Relative EC30 0.8 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)cs3)cnc21 CHEMBL131850 EC30 0.87 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(C(C)C)cc(-c2ccccc2)c1OCC(F)F CHEMBL424639 Synergy 1.0 nM
Cc1cc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1 CHEMBL100131 Relative EC30 1.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cccc(-c4ccc(C(=O)O)cc4)c3)ccc21 CHEMBL418570 AC50 1.0 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1CC(F)(F)F CHEMBL347437 Relative EC30 1.0 nM
CC1=C(/C=C/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1 CHEMBL705 EC50 1.0 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2ccc(F)cc2)cc(C(C)C)c1OCC(F)F CHEMBL133915 Synergy 1.1 nM
CC(C)c1cccc2ccc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL160622 Relative EC30 1.1 nM
CC(/C=C/C=C(\C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1)=C\C(=O)O CHEMBL89241 Ki 1.1 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2ccco2)cc(C(C)C)c1OCC(F)F CHEMBL130317 Synergy 1.2 nM
CCCCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(F)(F)C(F)(F)F)cc1C(C)C CHEMBL424269 Synergy 1.2 nM
Cc1ccc(C)c2sc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL100439 Relative EC30 1.3 nM
O=C(O)c1ccc(-c2ccc(-c3ccc4cccc(-c5ccccc5)c4c3)[nH]2)cc1 CHEMBL348635 Relative IC50 1.4 nM
CCCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(F)(F)C(F)(F)F)cc1C(C)C CHEMBL132568 Synergy 1.4 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2cccs2)cc(C(C)C)c1OCC(F)F CHEMBL130374 Synergy 1.4 nM
CCC(C)(C)c1cc(/C(C)=C(F)\C=C\C(C)=C\C(=O)O)c(OCC(F)F)c(C(C)(C)CC)c1 CHEMBL130231 Synergy 1.5 nM
CCCCOc1c(/C(C)=C(F)\C=C\C(C)=C\C(=O)O)cc(C(C)C)cc1C(C)C CHEMBL131826 Synergy 1.5 nM
CC(/C=C/C(F)=C(/C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1OCC(F)(F)F)=C\C(=O)O CHEMBL335242 Synergy 1.5 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2ccccc2F)cc(C(C)C)c1OCC(F)F CHEMBL422088 Synergy 1.5 nM
Cc1ccc(C2=CC(C)(C)Sc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL165629 IC50 1.5 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(-c2cccc(F)c2)cc(C(C)C)c1OCC(F)F CHEMBL130232 Synergy 1.6 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)[nH]n3)cnc21 CHEMBL337855 EC30 1.7 nM
CC(/C=C/C(F)=C(/C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1OCC(F)F)=C\C(=O)O CHEMBL111217 Synergy 1.8 nM
Cc1ccc(C)c2c1C=C(c1ccc(-c3ccc(C(=O)O)cc3)[nH]1)CO2 CHEMBL158065 Relative EC30 1.8 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)o3)cnc21 CHEMBL132033 EC30 1.8 nM
CC(/C=C/[C@@H]1C[C@]1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL75133 Synergy 1.9 nM
Cc1cc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1C CHEMBL297022 Relative EC30 2.0 nM
Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL358145 Kd 2.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)ccc21 CHEMBL326911 Kd 2.0 nM
Cc1cc(C)c2sc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1 CHEMBL98580 Relative EC30 2.4 nM
CC(/C=C/C=C(\C)c1ccc2c(C)ccc(C)c2c1)=C\C(=O)O CHEMBL158064 Relative IC50 2.7 nM
CCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(F)(F)C(F)(F)F)cc1C(C)C CHEMBL133896 Synergy 2.8 nM
Cc1ccc(C)c2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)ccc12 CHEMBL156929 Relative EC30 2.8 nM
CC1(C)CCC(C)(C)c2c1cc(C(=O)Nc1cc(F)c(C(=O)O)c(F)c1)c(O)c2Cl CHEMBL107430 Kd 3.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3cc(F)c(C(=O)O)c(F)c3)c(O)cc21 CHEMBL107054 Kd 3.0 nM
Cc1ccc2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)oc2c1C CHEMBL98218 Relative EC30 3.1 nM
CC(/C=C/C1CC1/C=C/C1=CC(C)(C)CCC1(C)C)=C\C(=O)O CHEMBL74331 Ki 3.1 nM
CCCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL109581 EC50 4.0 nM
CC1(C)CCC(C)(C)c2c1cc(C(=O)Nc1cc(F)c(C(=O)O)c(F)c1)c(O)c2Br CHEMBL439780 Kd 4.0 nM
Cc1cc2c(cc1C(=O)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL98172 EC50 4.0 nM
O=C(O)c1ccc(-c2ccc(OCCCCO)c(-c3ccc(N4CCCC4)c(C(F)(F)F)c3)c2)cc1 CHEMBL3934863 Kd(app) 4.0 nM
CC1(C)CCC(C)(C)c2c1cc(C(=O)Nc1ccc(C(=O)O)c(F)c1)c(O)c2Br CHEMBL317873 Kd 4.4 nM
Cc1cccc2c1C=C(c1ccc(-c3ccc(C(=O)O)cc3)[nH]1)CO2 CHEMBL157398 Relative EC30 4.5 nM
CC1(C)CCC(C)(C)c2nc(-c3csc(-c4ccc(C(=O)O)cc4)n3)cnc21 CHEMBL336311 EC30 5.2 nM
CC1(C)CCC(C)(C)c2cc3cc(-c4ccc(C(=O)O)cc4)ccc3cc21 CHEMBL36768 Ki 5.3 nM
Cc1ccc(C2=CC(C)(C)Oc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL162345 IC50 5.5 nM
COc1ccc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL98249 Relative EC30 6.0 nM
C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL1023 EC50 6.0 nM
Cc1ccc(C2=CC(C)(C)Oc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL163530 IC50 6.5 nM
Cc1cc2c(cc1C1(c3ccc(C(=O)O)cn3)CC1)C(C)(C)CCC2(C)C CHEMBL288436 Synergy 6.9 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3cc(F)c(C(=O)O)c(F)c3)ccc21 CHEMBL106527 Kd 7.0 nM
CCNc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C CHEMBL3907274 Kd(app) 8.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C CHEMBL3957342 Kd(app) 8.0 nM
Cc1sc(-c2ccc(C(=O)O)cc2)nc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4224900 EC50 8.2 nM
CCCOc1c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc(C(C)C)cc1C(F)(F)C(F)(F)F CHEMBL131122 Synergy 9.4 nM
CC(C)COc1cc(OC(C)C)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 CHEMBL381434 IC50 10.0 nM
CC1(C)CCC(C)(C)c2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL12585 EC50 11.0 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)c[nH]3)cnc21 CHEMBL337003 EC30 11.0 nM
CC1(C)CCSc2ccc(C#Cc3cccc(C(=O)O)n3)cc21 CHEMBL4212472 EC50 11.0 nM
O=C(O)c1ccc(NC(=O)c2cc(OCc3ccccc3F)cc(OCc3ccccc3F)c2)nc1 CHEMBL373364 IC50 11.1 nM
Cc1ccc(C2=CC(C)(C)Sc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL163223 Kd 13.0 nM
Cc1ccc(C2=CCC(C)(C)c3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL162393 Kd 13.0 nM
Cc1cc2c(cc1C1=NOC(c3ccc(C(=O)O)cc3)C1)C(C)(C)CCC2(C)C CHEMBL25337 AC50 14.0 nM
CCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL109847 EC50 14.0 nM
Cc1cccc2ccc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL156696 Relative IC50 15.0 nM
Cc1cc2c(cc1/C=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL441231 EC50 15.0 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)s3)cnc21 CHEMBL131810 EC30 15.0 nM
Cc1ccc(C2=CCC(C)(C)c3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL165417 Kd 15.0 nM
CC(=C\c1coc2cc3c(cc2c1=O)C(C)(C)CCC3(C)C)/C=C(\C)C(=O)O CHEMBL550796 IC50 15.0 nM
CCOCCOc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL512879 EC50 15.1 nM
CC(C)N1CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL80271 EC50 17.0 nM
CC1(C)CCC(C)(C)c2nc(-c3c[nH]c(-c4ccc(C(=O)O)cc4)n3)cnc21 CHEMBL336365 ED30 20.0 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2 CHEMBL1265 EC50 22.0 nM
C/C(=C\c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(C(=O)O)cc1 CHEMBL285179 EC50 24.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCS2 CHEMBL39344 EC50 27.0 nM
CC1(C)CCC(C)(C)c2cc(C/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL165843 EC50 30.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3945228 Kd(app) 30.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C CHEMBL3960035 Kd(app) 30.0 nM
CC(C)c1cccc2c(-c3ccccc3)cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)nc12 CHEMBL20066 IC50 31.2 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4217953 EC50 34.0 nM
Cn1c(-c2ccc(C(=O)O)cc2)ccc1-c1cnc2c(n1)C(C)(C)CCC2(C)C CHEMBL336147 EC30 38.0 nM
CC1(C)CC=C(c2ccc(C#N)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL346703 Kd 38.0 nM
Cc1ccc(C)c(-n2nc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2C(C)C)c1 CHEMBL348310 Relative IC50 39.0 nM
COc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL111589 EC50 40.0 nM
CCc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL155474 Kd 40.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCCO)ccc21 CHEMBL4205733 EC50 40.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCO)ccc21 CHEMBL4210595 EC50 43.0 nM
CC1(C)CC=C(c2ccc(C(F)(F)F)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL156997 Kd 44.0 nM
C/C(=C\c1ccc2c(c1)C(C)(C)CCS2)c1ccc(C(=O)O)cc1 CHEMBL73321 EC50 45.0 nM
C/C(=C/C=C/C(C)=C/C(=O)O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1OCC(F)F CHEMBL42314 Ki 54.0 nM
CC1(C)CCC(C)(C)c2cc(Cc3coc(/C=C/C(=O)O)c3)ccc21 CHEMBL63048 EC50 57.0 nM
CC(C)N1C(=O)CC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL430616 Kd 58.0 nM
CC1(C)CC=C(c2ccc(Cl)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL157160 Kd 58.0 nM
CC(/C=C/CC1(c2ccc3c(c2)C(C)(C)CCC3(C)C)CC1)=C\C(=O)O CHEMBL89331 EC50 59.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3O)ccc21 CHEMBL4203742 EC50 59.0 nM
COc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL346202 Kd 60.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3931870 Kd(app) 60.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)ccc1N1CCCC1 CHEMBL3916016 Kd(app) 60.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)ccc1N1CCCC1 CHEMBL3953756 Kd(app) 60.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C CHEMBL3939687 Kd(app) 60.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)cc1C(C)(C)C CHEMBL3936922 Kd(app) 60.0 nM
CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3)nc1 CHEMBL1657 EC50 63.0 nM
CC1(C)C=Cc2c(cc(O)c3c(=O)c4c5c(ccc4oc23)OC(C(C)(C)O)C5)O1 CHEMBL3400677 EC50 65.0 nM
C=C(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 CHEMBL82716 Kd 68.0 nM
C/C(=C/c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL86663 Kd 72.0 nM
CC1(C)CCC(C)(C)c2cc(C(=C(F)F)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL78587 Kd 73.0 nM
Cc1sc(-c2ccc(C(=O)O)cc2)nc1-c1ccccc1 CHEMBL4226389 EC50 77.5 nM
Cc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL27226 AC50 79.0 nM
CCOC(=O)c1ccc(-c2nc(-c3ccccc3)c(C)s2)cc1 CHEMBL4226012 EC50 82.0 nM
CC1(C)CC=C(c2ccc(F)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL157272 Kd 85.0 nM
CCOC(=O)c1ccc(-c2nc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c(C)s2)cc1 CHEMBL4226854 EC50 88.9 nM
Cc1cc(C)c2ccc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1 CHEMBL156299 Relative EC30 90.0 nM
CC(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL155421 Kd 90.0 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc(/C=C/C(=O)O)o3)ccc21 CHEMBL62047 Ki 93.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL344973 Kd 94.0 nM
CCc1cc2c(cc1/C(C)=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL284937 IC50 100.0 nM
CC1=C(/C=C\C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1 CHEMBL44478 EC50 102.0 nM
Cc1ccccc1C1=CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL156940 Kd 103.0 nM
CC(C)=CCc1c(O)ccc2oc3c4c(cc(O)c3c(=O)c12)OC(C)(C)C=C4 CHEMBL3400678 EC50 110.0 nM
CC1(C)CC=C(C#Cc2ccccc2)c2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL472172 IC50 114.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL309282 Kd 118.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCNC2CC2)cc1C(C)(C)C CHEMBL3954703 Kd(app) 120.0 nM
Cc1ccc(C2=CCC(C)(C)C=C2/C=C/C#Cc2ccc(C(=O)O)cc2)cc1 CHEMBL350485 Kd 129.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL147937 Kd 129.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C(C)(C)C CHEMBL74826 Ki 130.0 nM
CC1=C(/C=C/C#Cc2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL151870 Kd 135.0 nM
CCc1ccc(C2=C(/C=C/C#Cc3ccc(C(=O)O)cc3)C(C)(C)CCC2)cc1 CHEMBL349935 Kd 136.0 nM
CC(C)N1C(=O)CC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL76313 Kd 136.0 nM
CC1(C)CC=C(c2ccccc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL156903 Kd 147.0 nM
Cc1ccc(C2=C(/C=C/C#Cc3ccc(C(=O)O)cc3)C(C)(C)CCC2)cc1 CHEMBL349018 Kd 148.0 nM
CC1Oc2cc3oc4c(O)c5c(cc4c(=O)c3c(O)c2C1(C)C)C=CC(C)(C)O5 CHEMBL517514 EC50 170.0 nM
CC(C)(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL423954 Kd 178.0 nM
C/C(=C\c1ncc(C(=O)O)s1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL93577 EC50 210.0 nM
COc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4206237 EC50 212.0 nM
CCOC(=O)c1ccc(OC(=O)c2ccc3c(c2)C(C)(C)CCN3C(C)C)cc1 CHEMBL120210 EC50 217.0 nM
COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)C(C)(C)CC(C)(C)S3)cc1 CHEMBL139536 EC50 225.0 nM
CC1(C)CC=C(c2ccc(O)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL152740 Kd 229.0 nM
CC1=C(/C=C/C(C)=C/c2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL284264 EC50 240.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3892845 Kd(app) 250.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C CHEMBL3951072 Kd(app) 250.0 nM
CCc1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)ccc1N(CC)CC CHEMBL3891815 Kd(app) 250.0 nM
Cc1cccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL153974 Kd 276.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C(=O)Oc3ccc(C(=O)O)cc3)ccc21 CHEMBL148327 Kd 303.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3CCO)ccc21 CHEMBL4202830 EC50 317.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3CO)ccc21 CHEMBL4210099 EC50 336.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL32505 EC50 340.0 nM
CC1(C)CCCC(c2ccc(C(C)(C)C)cc2)=C1/C=C/C#Cc1ccc(C(=O)O)cc1 CHEMBL424190 Kd 350.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cccc(-c4ccc(C(=O)O)cc4)n3)ccc21 CHEMBL423654 AC50 370.0 nM
CC1(C)CCC(C)(C)c2cc(C(O)/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL97080 EC50 370.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C1(C)CCCCC1 CHEMBL356326 Ki 420.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CS2 CHEMBL118754 EC50 420.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2 CHEMBL146449 Ki 460.0 nM
COC[C@H](C)Oc1cc(O[C@@H](C)Cc2ccccc2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 CHEMBL205627 IC50 470.0 nM
CC1(C)CCC(C)(C)c2cc(C3=Cc4ccc(C(=O)O)cc4OC3)ccc21 CHEMBL75848 Ki 487.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N1CCCC1 CHEMBL3707313 Kd(app) 500.0 nM
CCc1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N(CC)CC CHEMBL3901588 Kd(app) 500.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(-c4noc(=O)[nH]4)cc3)ccc21 CHEMBL468623 EC50 520.0 nM
CC1=C(CC/C(C)=C/c2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL36718 EC50 550.0 nM
CC(/C=C/C1CC1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL69091 Kd 556.0 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL25361 Ki 580.0 nM
O=C(O)c1ccc(/C=C/c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1 CHEMBL146646 Ki 610.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCS3)cc1 CHEMBL125587 EC50 620.0 nM
CC(C)N1CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL311269 Kd 627.0 nM
CCCCOCCOc1nc(-c2ccc(C(=O)O)c(F)c2)sc1C CHEMBL198997 pEC50 630.96 nM
C/C(=C\c1ccc(C(=O)O)s1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL93538 EC50 690.0 nM
O=C(O)c1ccc2cc(-c3ccc(CCCO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL357917 Ki 695.0 nM
CC1(C)CCC(C)(C)c2cc(/C(=N\O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL77961 Kd 700.0 nM
CC(/C=C/CC1(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC1)=C\C(=O)O CHEMBL89581 EC50 733.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCO2)=C\C(=O)O CHEMBL35136 EC50 740.0 nM
COc1ccc(C2=Cc3ccc(C(=O)O)cc3OC2)cc1C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL75732 Ki 764.0 nM
CCOC(=O)c1ccc(OC(=O)c2cc3c(cc2C)N(C)CCC3(C)C)cc1 CHEMBL331642 EC50 796.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CO2)=C\C(=O)O CHEMBL340495 EC50 800.0 nM
O=C(O)c1ccc2c(c1)OCC(c1ccc(O)c(C34C[C@H]5C[C@@H](C3)C[C@@H](C4)C5)c1)=C2 CHEMBL75048 Ki 821.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc(O)c(C(C)(C)C)c1 CHEMBL348449 Ki 834.0 nM
CC1(C)CCC(C)(C)c2cc3c(cc21)Sc1ccccc1N=C3c1ccc(C(=O)O)cc1 CHEMBL337859 Ki 900.0 nM
CC1(C)CC=C(c2cccc(O)c2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL346429 Kd 919.0 nM
C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL96184 Kd 944.0 nM
CC1(C)CCC(C)(C)c2cc3c(cc21)Oc1ccccc1N=C3c1ccc(C(=O)O)cc1 CHEMBL334534 Ki 980.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1Br)C(C)(C)CCC2(C)C CHEMBL284167 EC50 989.0 nM
C/C(=C\c1cc(C(=O)O)no1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL357015 Kd 1000.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CS2)=C\C(=O)O CHEMBL330998 EC50 1000.0 nM