CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)co3)cnc21 CHEMBL131925 EC30 0.18 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL160376 Relative EC30 0.2 nM
CC1(C)CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL451835 EC50 0.3 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)o3)cnc21 CHEMBL132033 EC30 0.38 nM
CC1(C)CCC(C)(C)c2nc(-c3csc(-c4ccc(C(=O)O)cc4)n3)cnc21 CHEMBL336311 EC30 0.39 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1 CHEMBL38 Ki 0.4 nM
CC1(C)CCC(C)(C)c2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL12585 EC50 0.4 nM
Cc1cc2c(cc1/C=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL441231 EC50 0.4 nM
CC1(C)CCC(C)(C)c2nc(C(=O)Nc3ccc(C(=O)O)cc3)cnc21 CHEMBL432592 EC30 0.4 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL275311 Ki 0.5 nM
CC1=C(/C=C/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1 CHEMBL705 Ki 0.5 nM
C/C(=C\c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(C(=O)O)cc1 CHEMBL285179 EC50 0.5 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)cs3)cnc21 CHEMBL131850 EC30 0.5 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1C(C)(C)C CHEMBL159168 Relative EC30 0.63 nM
CC(/C=C/C=C(\C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1)=C\C(=O)O CHEMBL89241 Ki 0.7 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)s3)cnc21 CHEMBL131810 EC30 0.73 nM
CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3)nc1 CHEMBL1657 EC50 0.8 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)[nH]n3)cnc21 CHEMBL337855 EC30 0.85 nM
C=C(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 CHEMBL82716 Kd 1.1 nM
CC1(C)CCC(C)(C)c2cc(C(=O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL309282 Kd 1.2 nM
CC1(C)CCC(C)(C)c2cc(C(=C(F)F)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL78587 Kd 1.7 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1C(C)C CHEMBL159167 Relative EC30 1.8 nM
CC1=C(/C=C/C#Cc2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL151870 EC50 2.0 nM
Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL358145 Kd 2.0 nM
Cc1ccc(C2=CC(C)(C)Sc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL165629 IC50 2.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3945228 Kd(app) 2.0 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2 CHEMBL1265 EC50 2.0 nM
Cc1ccc(C)c2oc(-c3nc(-c4ccc(C(=O)O)cc4)no3)cc12 CHEMBL4459692 EC50 2.05 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cnc21 CHEMBL133725 EC30 2.5 nM
CC1(C)CCSc2ccc(C#Cc3cccc(C(=O)O)n3)cc21 CHEMBL4212472 EC50 2.5 nM
CC1(C)CCC(C)(C)c2cc3cc(-c4ccc(C(=O)O)cc4)ccc3cc21 CHEMBL36768 Ki 3.0 nM
CC(C)N1CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL80271 EC50 3.0 nM
CC1=C(/C=C\C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1 CHEMBL44478 EC50 3.3 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCO)ccc21 CHEMBL4210595 EC50 3.8 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)ccc21 CHEMBL134375 EC30 3.9 nM
CCc1ccc(C2=C(/C=C/C#Cc3ccc(C(=O)O)cc3)C(C)(C)CCC2)cc1 CHEMBL349935 Kd 4.0 nM
CC(C)N1C(=O)CC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL430616 EC50 4.0 nM
CC(C)N1C(=O)CC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL76313 EC50 4.0 nM
Cc1ccc(C2=CCC(C)(C)c3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL162393 Kd 4.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C CHEMBL3939687 Kd(app) 4.0 nM
CCc1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)ccc1N(CC)CC CHEMBL3891815 Kd(app) 4.0 nM
CCc1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N(CC)CC CHEMBL3901588 Kd(app) 4.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)ccc1N1CCCC1 CHEMBL3953756 Kd(app) 4.0 nM
O=C(O)c1ccc(-c2ccc(OCCCCO)c(-c3ccc(N4CCCC4)c(C(F)(F)F)c3)c2)cc1 CHEMBL3934863 Kd(app) 4.0 nM
CCNc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C CHEMBL3907274 Kd(app) 4.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cccc(-c4ccc(C(=O)O)cc4)c3)ccc21 CHEMBL418570 AC50 4.3 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)c[nH]3)cnc21 CHEMBL337003 EC30 4.5 nM
CC1=C(/C=C/C(C)=C/c2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL284264 EC50 5.0 nM
CC1(C)CCC(C)(C)c2cc(C/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL165843 Kd 5.0 nM
C/C(=C/c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL86663 Kd 5.0 nM
COc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4206237 EC50 5.0 nM
Cc1ccc(C2=C(/C=C/C#Cc3ccc(C(=O)O)cc3)C(C)(C)CCC2)cc1 CHEMBL349018 Kd 6.0 nM
Cc1ccc(C2=CCC(C)(C)c3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL165417 Kd 6.0 nM
Cc1ccc(C2=CC(C)(C)Oc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL163530 IC50 6.5 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCCO)ccc21 CHEMBL4205733 EC50 6.8 nM
Cc1ccc(C2=CC(C)(C)Oc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL162345 Kd 7.0 nM
O=C(O)c1ccc(NC(=O)c2cc(OCc3ccccc3F)cc(OCc3ccccc3F)c2)nc1 CHEMBL373364 IC50 7.0 nM
CCCCOCCOc1nc(-c2ccc(C(=O)O)c(F)c2)sc1C CHEMBL198997 pEC50 7.943 nM
COc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL111589 EC50 8.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C CHEMBL3957342 Kd(app) 8.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C CHEMBL3960035 Kd(app) 8.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)cc1C(C)(C)C CHEMBL3936922 Kd(app) 8.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C CHEMBL3951072 Kd(app) 8.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)ccc1N1CCCC1 CHEMBL3916016 Kd(app) 8.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3931870 Kd(app) 8.0 nM
O=C(O)c1ccc(-c2ccc(-c3cc4c(C(F)(F)F)ccc(F)c4o3)[nH]2)cc1 CHEMBL430677 Relative EC30 8.5 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL69367 EC50 8.6 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3O)ccc21 CHEMBL4203742 EC50 8.6 nM
Cc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL25088 AC50 10.0 nM
CCCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL109581 EC50 10.0 nM
CC(C)N1CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL311269 EC50 10.0 nM
CCc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL155474 Kd 10.0 nM
CC(C)(C)c1ccc(C#Cc2ccc(C(=O)O)cc2)cc1 CHEMBL457775 EC50 10.0 nM
CC(/C=C/C=C(\C)c1ccc2c(C)ccc(C)c2c1)=C\C(=O)O CHEMBL158064 Relative EC30 11.0 nM
CC(/C=C/C1CC1/C=C/C1=CC(C)(C)CCC1(C)C)=C\C(=O)O CHEMBL74331 Ki 11.0 nM
CC(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL155421 Kd 11.0 nM
Cc1sc(-c2ccc(C(=O)O)cc2)nc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4224900 EC50 11.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C(C)(C)C CHEMBL74826 Ki 12.0 nM
CCOC(=O)c1ccc(-c2nc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c(C)s2)cc1 CHEMBL4226854 EC50 12.1 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL25361 Ki 13.0 nM
Cc1ccc(C2=CC(C)(C)Sc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL163223 Kd 13.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCNC3CC3)ccc21 CHEMBL4215021 EC50 13.0 nM
Cn1c(-c2ccc(C(=O)O)cc2)ccc1-c1cnc2c(n1)C(C)(C)CCC2(C)C CHEMBL336147 EC30 14.0 nM
CC1(C)CC=C(c2ccc(C#N)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL346703 Kd 14.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCS2 CHEMBL39344 EC50 15.0 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1CC(F)(F)F CHEMBL347437 Relative EC30 15.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N1CCCC1 CHEMBL3707313 Kd(app) 15.0 nM
CCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL197292 Log EC50 15.85 nM
CCCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL198794 Log EC50 15.85 nM
COc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL346202 Kd 16.0 nM
CC1(C)CCC(C)(C)c2cc(C(=C3CC3)c3ccc(C(=O)O)cc3)ccc21 CHEMBL280140 AC50 17.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C1(C)CCCCC1 CHEMBL356326 Ki 17.0 nM
CC(/C=C/CC1(c2ccc3c(c2)C(C)(C)CCC3(C)C)CC1)=C\C(=O)O CHEMBL89331 EC50 17.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CS2 CHEMBL118754 EC50 18.0 nM
CC1(C)CC=C(c2ccc(Cl)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL157160 Kd 18.0 nM
CCCCOCCOc1ccc(-c2ccc(C(=O)O)c(F)c2)cc1 CHEMBL513760 pEC50 19.95 nM
CC1=C(CC/C(C)=C/c2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL36718 EC50 20.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL147937 Kd 20.0 nM
C/C(=C\c1ccc(C(=O)O)cn1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL92926 EC50 21.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1Br)C(C)(C)CCC2(C)C CHEMBL284167 EC50 21.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1Cl)C(C)(C)CCC2(C)C CHEMBL36464 EC50 21.0 nM
O=C(O)c1ccc2cc(-c3ccc(CCCO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL357917 Ki 21.0 nM
CC(C)(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL423954 Kd 21.0 nM
C/C(=C\c1ccc(C(=O)O)s1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL91718 EC50 23.0 nM
Cc1ccc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL48353 Relative EC30 25.0 nM
CC1(C)CCCC(c2ccc(C(C)(C)C)cc2)=C1/C=C/C#Cc1ccc(C(=O)O)cc1 CHEMBL424190 IC50 25.0 nM
CCCCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL371684 Log EC50 25.12 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C1(C)CCCCC1 CHEMBL345298 Ki 26.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C(=O)Oc3ccc(C(=O)O)cc3)ccc21 CHEMBL148327 EC50 26.0 nM
CC1(C)CCC(C)(C)c2cc(C#Cc3ccc(-c4noc(=O)[nH]4)cc3)ccc21 CHEMBL468608 EC50 26.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3CO)ccc21 CHEMBL4210099 EC50 26.0 nM
C/C(=C\c1ccc(C(=O)O)s1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL93538 EC50 29.0 nM
CC1(C)CC=C(c2ccc(C(F)(F)F)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL156997 Kd 29.0 nM
Cc1ccccc1C1=CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL156940 Kd 29.0 nM
CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21 CHEMBL25202 Ki 30.0 nM
CCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL109847 EC50 31.0 nM
CCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL469323 pEC50 31.62 nM
CC1(C)CC=C(c2ccccc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL156903 Kd 33.0 nM
Cc1ccc(C2=CCC(C)(C)C=C2/C=C/C#Cc2ccc(C(=O)O)cc2)cc1 CHEMBL350485 Kd 35.0 nM
CC1(C)CCC(C)(C)c2cc(C3=Cc4ccc(C(=O)O)cc4OC3)ccc21 CHEMBL75848 Ki 36.0 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C(C)(C)C CHEMBL146092 Ki 36.0 nM
CC1(C)CCNc2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL75741 EC50 36.0 nM
CCCCCCCCc1ccc(-c2ccc(C(=O)O)c(F)c2)cc1 CHEMBL524687 pEC50 39.81 nM
CCCCCCNC(=O)COc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL472238 pEC50 39.81 nM
C/C(=C\c1ccc2c(c1)C(C)(C)CCS2)c1ccc(C(=O)O)cc1 CHEMBL73321 EC50 40.0 nM
CC1(C)CCC(C)(C)c2nc(-c3c[nH]c(-c4ccc(C(=O)O)cc4)n3)cnc21 CHEMBL336365 EC30 40.0 nM
CC(=C\c1coc2cc3c(cc2c1=O)C(C)(C)CCC3(C)C)/C=C(\C)C(=O)O CHEMBL550796 IC50 40.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4217953 EC50 40.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3CCO)ccc21 CHEMBL4202830 EC50 40.0 nM
CCOC(=O)c1ccc(OC(=O)c2ccc3c(c2)C(C)(C)CCN3C(C)C)cc1 CHEMBL120210 EC50 41.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCS2)=C\C(=O)O CHEMBL34292 EC50 43.0 nM
CC1(C)CCC(C)(C)c2cc(/C(=N/N)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL82609 Kd 43.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)ccc21 CHEMBL326911 EC50 45.0 nM
C/C(=C\c1ncc(C(=O)O)s1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL93577 EC50 46.0 nM
C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL1023 Ki 50.0 nM
CC1(C)CCC(C)(C)c2cc(/C(=N\O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL77961 Kd 50.0 nM
CCCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL198467 Log EC50 50.12 nM
Cc1cccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL153974 Kd 51.0 nM
CC1(C)CC=C(c2ccc(F)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL157272 Kd 52.0 nM
CCOCCOc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL512879 EC50 56.7 nM
CCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL365798 Log EC50 63.1 nM
CCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL470588 pEC50 63.1 nM
CCCCOCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL472476 pEC50 63.1 nM
CC(C)CCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL469281 pEC50 63.1 nM
O=C(O)c1ccc(/C=C/c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1 CHEMBL146646 Ki 70.0 nM
COc1ccc(C2=Cc3ccc(C(=O)O)cc3OC2)cc1C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL75732 Ki 71.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCO2)=C\C(=O)O CHEMBL35136 EC50 72.0 nM
CC1(C)CC=C(c2ccc(O)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL152740 Kd 72.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL32505 EC50 74.0 nM
CCc1cc2c(cc1/C(C)=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL284937 IC50 75.0 nM
Cc1sc(-c2ccc(C(=O)O)cc2)nc1-c1ccccc1 CHEMBL4226389 EC50 77.8 nM
CC(C)c1cccc2ccc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL160622 Relative EC30 78.0 nM
CCCCOCCOc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL471422 pEC50 79.43 nM
CC1(C)C=C(/C=C/C#Cc2ccc(C(=O)O)cc2)C(c2ccc(C(C)(C)C)cc2)=CC1 CHEMBL164176 Kd 87.0 nM
O=C(O)c1ccc2cc(-c3ccc(OCC(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL147545 Ki 89.0 nM
CC1(C)CCC(C)(C)c2cc(C3COc4cc(C(=O)O)ccc4C3)ccc21 CHEMBL75527 Ki 90.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc(O)c(C2(C)CCCCC2)c1 CHEMBL345022 Ki 90.0 nM
Cc1cccc2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)oc12 CHEMBL98263 Relative EC30 92.0 nM
CCOC(=O)c1ccc(OC(=O)c2cc3c(cc2C)N(C)CCC3(C)C)cc1 CHEMBL331642 EC50 92.0 nM
CCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL470587 pEC50 100.0 nM
CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2C)cc1 CHEMBL472032 pEC50 100.0 nM
CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2F)cc1 CHEMBL472213 pEC50 100.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc(O)c(C(C)(C)C)c1 CHEMBL348449 Ki 105.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2 CHEMBL146449 Ki 105.0 nM
O=C(O)c1ccc(-c2ccc(-c3cc4c(Cl)ccc(Cl)c4o3)[nH]2)cc1 CHEMBL46229 Relative EC30 110.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCS3)cc1 CHEMBL125587 EC50 110.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL344973 EC50 115.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3892845 Kd(app) 120.0 nM
CCCCCCCCc1ccc(-c2ccc(C(=O)O)cc2)cc1 CHEMBL425027 Log EC50 125.89 nM
CCCCCCCc1ccc(-c2ccc(C(=O)O)c(F)c2)cc1 CHEMBL471197 pEC50 125.89 nM
CCCOCCOc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL471421 pEC50 125.89 nM
Cc1ccc(C)c2sc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL100439 Relative EC30 130.0 nM
CC(C)COc1cc(OC(C)C)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 CHEMBL381434 IC50 135.0 nM
CCOC(=O)c1ccc(-c2nc(-c3ccccc3)c(C)s2)cc1 CHEMBL4226012 EC50 136.3 nM
CC(/C=C/CC1(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC1)=C\C(=O)O CHEMBL89581 EC50 139.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cccc(-c4ccc(C(=O)O)cc4)n3)ccc21 CHEMBL423654 AC50 140.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCO3)cc1 CHEMBL34464 EC50 140.0 nM
CC1(C)CCC(C)(C)c2cc(C(O)/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL97080 EC50 140.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1C(C)C)C(C)(C)CCC2(C)C CHEMBL424636 IC50 150.0 nM
O=C(O)c1ccc2cc(-c3ccc(CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL422490 Ki 156.0 nM
O=C(O)c1ccc2cc(-c3ccc(CC(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL146636 Ki 158.0 nM
Cc1ccc2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)oc2c1C CHEMBL98218 Relative EC30 160.0 nM
CC1(C)CC=C(c2cccc(O)c2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL346429 Kd 162.0 nM
CC1(C)CCNc2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL80820 EC50 170.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCO2 CHEMBL21518 EC50 190.0 nM
Cc1cc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1C CHEMBL297022 Relative EC30 200.0 nM
O=C(O)/C=C/c1ccc(-c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1 CHEMBL442016 EC50 200.0 nM
CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)cc[n+]([O-])c3C)CC2)CC1 CHEMBL78535 Relative EC30 210.0 nM
CC1(C)CCOc2ccc(-c3ccc4cc(C(=O)O)ccc4c3)cc21 CHEMBL342051 Ki 210.0 nM
CN1c2cc3c(cc2N=C(c2ccc(C(=O)O)cc2)c2ccccc21)C(C)(C)CCC3(C)C CHEMBL37708 Ki 220.0 nM
C/C(=C\c1ncc(C(=O)O)s1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL328481 EC50 220.0 nM
O=C(O)c1ccc2cc(-c3ccc(O)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL1180 EC50 226.0 nM
Cc1ccc(C)c2c1C=C(c1ccc(-c3ccc(C(=O)O)cc3)[nH]1)CO2 CHEMBL158065 Relative EC30 240.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1 CHEMBL4210286 EC50 248.0 nM
Cc1ccc(C)c2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)ccc12 CHEMBL156929 Relative EC30 250.0 nM
C/C(=C/c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCS2 CHEMBL415449 EC50 250.0 nM
COC(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 CHEMBL78835 Kd 250.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCNC2CC2)cc1C(C)(C)C CHEMBL3954703 Kd(app) 250.0 nM
CCCCOCCOc1cc(C)c(-c2ccc(C(=O)O)cc2)cc1C CHEMBL469322 pEC50 251.19 nM
CCOC(=O)c1ccc(OC(=O)c2ccc3c(c2)C(C)(C)CCN3C)cc1 CHEMBL422607 EC50 256.0 nM
Cc1cc(C)cc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL155325 Kd 274.0 nM
CCCCCCCN1CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL308967 EC50 280.0 nM
CC(/C=C/C1(c2ccc3c(c2)C(C)(C)CCC3(C)C)CC1)=C\C(=O)O CHEMBL93518 EC50 287.0 nM
O=C(O)c1ccc2cc(-c3ccc(C(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL357603 Ki 288.0 nM
C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL96184 EC50 304.0 nM
CC1(C)CCC(C)(C)c2cc3c(cc21)Oc1ccccc1N=C3c1ccc(C(=O)O)cc1 CHEMBL334534 Ki 320.0 nM
CC1(C)CCC(C)(C)c2cc3c(cc21)Sc1ccccc1N=C3c1ccc(C(=O)O)cc1 CHEMBL337859 Ki 320.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CO2 CHEMBL120759 EC50 320.0 nM
C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1F)C(C)(C)CCC2(C)C CHEMBL330593 EC50 337.0 nM
CC(/C=C/C1=C(c2ccc3c(c2)C(C)(C)CCC3(C)C)CCC1)=C\C(=O)O CHEMBL79234 EC50 339.0 nM
CC(/C=C/C1CC1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL69091 EC50 340.0 nM
CC1=C(C#Cc2ccc3cc(C(=O)O)ccc3c2)C(C)(C)CCC1 CHEMBL151672 EC50 355.0 nM
Cc1cc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1 CHEMBL100131 Relative EC30 380.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)c3ccc(C(=O)O)cc3)c(F)cc21 CHEMBL419166 EC50 395.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CO3)cc1 CHEMBL37672 EC50 430.0 nM
C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1Cl)C(C)(C)CCC2(C)C CHEMBL101609 EC50 436.0 nM
CN1c2cc3c(cc2N=C(c2ccc(C(=O)O)cc2)c2ccc4ccccc4c21)C(C)(C)CCC3(C)C CHEMBL298373 Ki 500.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CC(O)CO)cc1C(C)(C)C CHEMBL3926084 Kd(app) 500.0 nM
CC1(C)CCC(C)(C)c2cc([C@@H](O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL81273 Kd 531.0 nM
C=C1C[C@H](c2ccc3c(c2)C(C)(C)CCC3(C)C)[C@@H](/C=C/C(C)=C/C(=O)O)C1 CHEMBL312233 EC50 559.0 nM
CC1(C)CCC(C)(C)c2cc(Sc3ccc(C(=O)O)cc3)ccc21 CHEMBL119781 EC50 570.0 nM
CCCCCCCCc1ccc(-c2ccc(C(=O)O)c(C)c2)cc1 CHEMBL472236 pEC50 630.96 nM
CC(/C=C/[C@H]1CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL80236 EC50 637.0 nM
CC1(c2cc(-c3ccc4cc(C(=O)O)ccc4c3)ccc2O)CCCCC1 CHEMBL148231 Ki 660.0 nM
CC1(C)CCC(C)(C)c2cc(C(O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL82089 Kd 679.0 nM
CN1c2ccccc2N=C(c2ccc(C(=O)O)cc2)c2cc3c(cc21)C(C)(C)CCC3(C)C CHEMBL334330 Ki 680.0 nM
COc1ccc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL98249 Relative EC30 730.0 nM
Cc1cc2c(cc1-c1ncc(-c3ccc(C(=O)O)cc3)s1)C(C)(C)CCC2(C)C CHEMBL25038 AC50 740.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CO2)=C\C(=O)O CHEMBL340495 EC50 770.0 nM
CC(/C=C/C1(c2cc3c(cc2C)C(C)(C)CCC3(C)C)CCCC1)=C\C(=O)O CHEMBL92394 EC50 809.0 nM
CC(/C=C/[C@@]1(C)CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL312395 EC50 809.0 nM
CC1(C)CCC(C)(C)c2cc3c(cc21)Cc1ccccc1N=C3c1ccc(C(=O)O)cc1 CHEMBL134834 Ki 810.0 nM
CC(C)(C)c1ccc(C#Cc2ccc(-c3noc(=O)[nH]3)cc2)cc1 CHEMBL511855 EC50 820.0 nM
O=C(O)c1ccc(-c2ccc(-c3ccc4cccc(-c5ccccc5)c4c3)[nH]2)cc1 CHEMBL348635 Relative EC30 880.0 nM
CC1(C)CC(=O)Nc2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL306999 EC50 1000.0 nM
CCCCCCCc1cnc(-c2ccc(C(=O)O)cc2)nc1 CHEMBL471423 pEC50 1000.0 nM