CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1 CHEMBL38 Ki 0.04 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C CHEMBL3939687 Kd(app) 0.12 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCO)ccc21 CHEMBL4210595 EC50 0.22 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL160376 Relative EC30 0.24 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)cc1C(C)(C)C CHEMBL3936922 Kd(app) 0.25 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3945228 Kd(app) 0.25 nM
CCNc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C CHEMBL3907274 Kd(app) 0.25 nM
CC1(C)CCC(C)(C)c2nc(-c3csc(-c4ccc(C(=O)O)cc4)n3)cnc21 CHEMBL336311 EC30 0.34 nM
CC(/C=C/C=C(\C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1)=C\C(=O)O CHEMBL89241 EC50 0.34 nM
C/C(=C\c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(C(=O)O)cc1 CHEMBL285179 EC50 0.4 nM
CC1(C)CCC(C)(C)c2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL12585 EC50 0.4 nM
Cc1ccc(C2=CC(C)(C)Sc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL165629 IC50 0.5 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C CHEMBL3957342 Kd(app) 0.5 nM
CCc1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N(CC)CC CHEMBL3901588 Kd(app) 0.5 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3931870 Kd(app) 0.5 nM
CC1(C)CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL451835 EC50 0.6 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)cs3)cnc21 CHEMBL131850 EC30 0.72 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)co3)cnc21 CHEMBL131925 EC30 0.76 nM
CC1=C(/C=C/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1 CHEMBL705 Kd 0.8 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCCO)ccc21 CHEMBL4205733 EC50 0.92 nM
Cc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL25088 AC50 1.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)ccc1N1CCCC1 CHEMBL3953756 Kd(app) 1.0 nM
C=C(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 CHEMBL82716 Kd 1.3 nM
Cc1cc2c(cc1/C=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL441231 EC50 1.4 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3CCO)ccc21 CHEMBL4202830 EC50 1.4 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)o3)cnc21 CHEMBL132033 EC30 1.5 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)c[nH]3)cnc21 CHEMBL337003 EC30 1.6 nM
CC1(C)CCC(C)(C)c2nc(C(=O)Nc3ccc(C(=O)O)cc3)cnc21 CHEMBL432592 EC30 1.6 nM
CC1(C)CCC(C)(C)c2cc3cc(-c4ccc(C(=O)O)cc4)ccc3cc21 CHEMBL36768 Ki 2.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL275311 EC50 2.0 nM
Cc1ccc(C2=CC(C)(C)Oc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL162345 IC50 2.0 nM
Cc1ccc(C2=CCC(C)(C)c3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)cc1 CHEMBL162393 IC50 2.0 nM
Cc1ccc(C2=CCC(C)(C)c3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL165417 IC50 2.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C CHEMBL3960035 Kd(app) 2.0 nM
CCc1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)ccc1N(CC)CC CHEMBL3891815 Kd(app) 2.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)ccc1N1CCCC1 CHEMBL3916016 Kd(app) 2.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N1CCCC1 CHEMBL3707313 Kd(app) 2.0 nM
COc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4206237 EC50 2.0 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)s3)cnc21 CHEMBL131810 EC30 2.1 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)nn3-c3ccc(S(C)(=O)=O)cc3)ccc21 CHEMBL3814574 KB 2.2 nM
CC1(C)CCC(C)(C)c2cc(-c3cccc(-c4ccc(C(=O)O)cc4)c3)ccc21 CHEMBL418570 AC50 2.3 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1C(C)(C)C CHEMBL159168 Relative EC30 2.3 nM
CCc1ccc(C2=C(/C=C/C#Cc3ccc(C(=O)O)cc3)C(C)(C)CCC2)cc1 CHEMBL349935 IC50 3.0 nM
Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL358145 IC50 3.0 nM
CC(C)N1CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL80271 EC50 3.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL309282 Kd 3.0 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2 CHEMBL1265 EC50 3.1 nM
CC1(C)CCC(C)(C)c2cc(/C(=N\O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL77961 Kd 3.3 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)ccc21 CHEMBL134375 EC30 3.5 nM
CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)[nH]n3)cnc21 CHEMBL337855 EC30 3.9 nM
Cc1ccc(C2=CCC(C)(C)C=C2/C=C/C#Cc2ccc(C(=O)O)cc2)cc1 CHEMBL350485 Kd 4.0 nM
CC1(C)CCC(C)(C)c2cc(C/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL165843 EC50 4.0 nM
CC(C)N1C(=O)CC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL76313 EC50 4.0 nM
Cc1ccc(C2=CC(C)(C)Oc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL163530 IC50 4.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3CO)ccc21 CHEMBL4210099 EC50 4.4 nM
CC1(C)CCCC(c2ccc(C(C)(C)C)cc2)=C1/C=C/C#Cc1ccc(C(=O)O)cc1 CHEMBL424190 Kd 5.0 nM
Cc1ccc(C2=C(/C=C/C#Cc3ccc(C(=O)O)cc3)C(C)(C)CCC2)cc1 CHEMBL349018 IC50 5.0 nM
CC1=C(/C=C\C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC1 CHEMBL44478 EC50 6.0 nM
CC(C)N1CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL311269 EC50 6.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4217953 EC50 6.0 nM
CN1CCN(C(=O)c2ccc(-n3nc(-c4ccc(C(=O)O)cc4)cc3-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cc2)CC1 CHEMBL3814815 KB 7.1 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)nn2-c2ccc(C(=O)N3CCOCC3)cc2)cc(C(C)(C)C)c1 CHEMBL3813702 KB 7.2 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)c(C)c2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4216161 EC50 7.4 nM
CC1(C)CCC(C)(C)c2cc(C(=C(F)F)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL78587 Kd 7.5 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CS2)=C\C(=O)O CHEMBL330998 EC50 8.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CC(O)CO)cc1C(C)(C)C CHEMBL3926084 Kd(app) 8.0 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3OCCCNC3CC3)ccc21 CHEMBL4215021 EC50 8.0 nM
CC1=C(/C=C/C#Cc2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL151870 EC50 10.0 nM
CC(C)(C)c1ccc(C#Cc2ccc(C(=O)O)cc2)cc1 CHEMBL457775 EC50 10.0 nM
CC1(C)CCSc2ccc(C#Cc3cccc(C(=O)O)n3)cc21 CHEMBL4212472 EC50 11.0 nM
CN(C)S(=O)(=O)c1ccc(-n2nc(-c3ccc(C(=O)O)cc3)cc2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc1 CHEMBL3814015 KB 11.1 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCS2)=C\C(=O)O CHEMBL34292 EC50 12.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C(C)(C)C CHEMBL74826 Ki 13.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21 CHEMBL69367 EC50 13.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)nn2-c2ccc(S(C)(=O)=O)cc2)cc(C(C)(C)C)c1 CHEMBL3813807 KB 13.5 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1C(C)C CHEMBL159167 Relative EC30 14.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)nn2-c2ccc(C(N)=O)cc2)cc(C(C)(C)C)c1 CHEMBL3813975 KB 14.7 nM
C/C(=C\c1ccc(C(=O)O)s1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL93538 EC50 15.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)c(Cl)c2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4207786 EC50 15.0 nM
COc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL111589 EC50 17.0 nM
Cc1ccc(C2=CC(C)(C)Sc3cc4ccc(-c5ccc(C(=O)O)cc5)cc4cc32)s1 CHEMBL163223 Kd 18.0 nM
CC1(C)CC=C(c2ccccc2)c2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL2385268 KB 18.5 nM
CC1(C)CCC(C)(C)c2cc(C3=Cc4ccc(C(=O)O)cc4OC3)ccc21 CHEMBL75848 Ki 19.0 nM
CCc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL155474 Kd 19.0 nM
O=C(O)c1ccc(/C=C/c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1 CHEMBL146646 Ki 20.0 nM
CC(C)N1C(=O)CC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL430616 EC50 20.0 nM
CC1(C)CCC(C)(C)c2nc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cnc21 CHEMBL133725 EC30 20.0 nM
CN(C)C(=O)c1ccc(-n2nc(-c3ccc(C(=O)O)cc3)cc2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)cc1 CHEMBL3814385 KB 21.3 nM
CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3O)ccc21 CHEMBL4203742 EC50 22.0 nM
CCc1cc2c(cc1/C(C)=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C CHEMBL284937 EC50 23.0 nM
CC(/C=C/CC1(c2ccc3c(c2)C(C)(C)CCC3(C)C)CC1)=C\C(=O)O CHEMBL89331 EC50 24.0 nM
C/C(=C/c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL86663 Kd 26.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc(O)c(C2(C)CCCCC2)c1 CHEMBL345022 Ki 27.0 nM
CC1(C)CC=C(c2ccc(Cl)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL157160 Kd 27.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C1(C)CCCCC1 CHEMBL356326 Ki 29.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCS2 CHEMBL39344 EC50 30.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CS2 CHEMBL118754 EC50 30.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C CHEMBL3951072 Kd(app) 30.0 nM
O=C(O)c1ccc(-c2ccc(OCCCCO)c(-c3ccc(N4CCCC4)c(C(F)(F)F)c3)c2)cc1 CHEMBL3934863 Kd(app) 30.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C CHEMBL3892845 Kd(app) 30.0 nM
CC(/C=C/C1CC1/C=C/C1=CC(C)(C)CCC1(C)C)=C\C(=O)O CHEMBL74331 Ki 32.0 nM
O=C(O)c1ccc2cc(-c3ccc(CC(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL146636 Ki 34.0 nM
C/C(=C\c1ncc(C(=O)O)s1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL93577 EC50 34.0 nM
CC1=C(/C=C/C(C)=C/c2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL284264 EC50 35.0 nM
Cc1ccccc1C1=CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL156940 Kd 35.0 nM
COc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL346202 Kd 36.0 nM
C/C(=C\c1ccc(C(=O)O)s1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL91718 EC50 37.0 nM
CC1(C)CCC(C)(C)c2nc(-c3c[nH]c(-c4ccc(C(=O)O)cc4)n3)cnc21 CHEMBL336365 EC30 39.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CCO2)=C\C(=O)O CHEMBL35136 EC50 39.0 nM
CC1(C)CCC(C)(C)c2cc(-c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL25361 Ki 40.0 nM
CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3)nc1 CHEMBL1657 EC50 40.0 nM
CC(=C\c1coc2cc3c(cc2c1=O)C(C)(C)CCC3(C)C)/C=C(\C)C(=O)O CHEMBL550796 IC50 40.0 nM
CC1(C)CC=C(c2ccccc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL156903 Kd 42.0 nM
CC1(C)CCC(C)(C)c2cc(C(O)/C=C/c3ccc(C(=O)O)cc3)ccc21 CHEMBL97080 EC50 46.0 nM
C/C(=C\c1ccc2c(c1)C(C)(C)CCS2)c1ccc(C(=O)O)cc1 CHEMBL73321 EC50 47.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2OC)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4217018 EC50 47.0 nM
O=C(O)c1ccc2cc(-c3ccc(O)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL1180 EC50 49.0 nM
CC1(C)CC=C(c2ccc(C#N)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL346703 Kd 51.0 nM
CC1(C)CCC(C)(C)c2cc(C(O)C(=O)Nc3ccc(C(=O)O)cc3F)ccc21 CHEMBL4216904 EC50 51.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc(O)c(C23CC4CC(CC(C4)C2)C3)c1 CHEMBL421773 Ki 53.0 nM
CC1(C)CCNc2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL75741 EC50 54.0 nM
CC1(C)CC=C(c2ccc(C(F)(F)F)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL156997 Kd 57.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1N1CCCC1=O CHEMBL3910072 Kd(app) 60.0 nM
COCCOCOc1c(Cl)cc(-c2ccc(C(=O)O)cc2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4214493 EC50 60.0 nM
CC1(C)CCC(C)(C)c2cc(C(O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL82089 Kd 64.0 nM
Cc1cccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL153974 Kd 67.0 nM
CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)ccc1NCCCCO CHEMBL4207978 EC50 67.0 nM
C/C(=C/c1ccc(C(=O)O)cc1)c1ccc2c(c1)C1CCC2C1 CHEMBL84681 EC50 70.0 nM
O=C(O)c1ccc2cc(-c3ccc(CCCO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL357917 Ki 72.0 nM
CC1(C)CCC(C)(C)c2cc([C@@H](O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL81273 Kd 75.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1Cl)C(C)(C)CCC2(C)C CHEMBL36464 EC50 77.0 nM
CC1(C)CC=C(c2ccc(F)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL157272 Kd 82.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCS3)cc1 CHEMBL125587 EC50 84.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc(O)c(C(C)(C)C)c1 CHEMBL348449 Ki 85.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cn2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4212684 EC50 85.0 nM
CC(C)c1cccc2ccc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL160622 Relative EC30 88.0 nM
CC(C)c1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nn1CC(F)(F)F CHEMBL347437 Relative EC30 88.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1Br)C(C)(C)CCC2(C)C CHEMBL284167 EC50 91.0 nM
CC1(C)CCC(C)(C)c2cc(C#Cc3ccc(-c4noc(=O)[nH]4)cc3)ccc21 CHEMBL468608 EC50 91.0 nM
CC(C)(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL423954 Kd 94.0 nM
COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2 CHEMBL146449 Ki 95.0 nM
CC1(C)CCC(C)(C)c2cc(/C(=N/N)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL82609 Kd 95.0 nM
CC1(C)CC=C(c2ccc(O)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL152740 Kd 98.0 nM
Cc1sc(-c2ccc(C(=O)O)cc2)nc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4224900 EC50 98.9 nM
CC1(C)CCC(C)(C)c2cc(-c3ccccc3-c3ccc(C(=O)O)cc3)ccc21 CHEMBL89253 EC50 100.0 nM
CC1(C)CC=C(c2cccs2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL147937 Kd 104.0 nM
Cc1sc(-c2ccc(C(=O)O)cc2)nc1-c1ccccc1 CHEMBL4226389 EC50 109.2 nM
O=C(O)c1ccc(-c2ccc(-c3cc4c(C(F)(F)F)ccc(F)c4o3)[nH]2)cc1 CHEMBL430677 Relative EC30 110.0 nM
Cn1c(-c2ccc(C(=O)O)cc2)ccc1-c1cnc2c(n1)C(C)(C)CCC2(C)C CHEMBL336147 EC30 120.0 nM
CCN(C(C)=O)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCNC2CC2)cc1C(C)(C)C CHEMBL3954703 Kd(app) 120.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2C)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4215630 EC50 120.0 nM
CCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL109847 EC50 121.0 nM
CC1(c2cc(-c3ccc4cc(C(=O)O)ccc4c3)ccc2O)CCCCC1 CHEMBL148231 Ki 121.0 nM
CC1(C)CCNc2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 CHEMBL80820 EC50 130.0 nM
C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL1023 Ki 130.0 nM
CCOCCOc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL512879 EC50 141.3 nM
CC(/C=C/C1(c2cc3c(cc2C)C(C)(C)CCC3(C)C)CC1)=C\C(=O)O CHEMBL92284 EC50 144.0 nM
O=C(O)c1ccc2c(c1)OCC(c1ccc(O)c(C34C[C@H]5C[C@@H](C3)C[C@@H](C4)C5)c1)=C2 CHEMBL75048 Ki 148.0 nM
CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21 CHEMBL25202 EC30 150.0 nM
O=C(O)c1ccc2cc(-c3ccc(OCC(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL147545 Ki 151.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL32505 EC50 152.0 nM
COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)C(C)(C)CC(C)(C)S3)cc1 CHEMBL139536 EC50 152.0 nM
O=C(O)c1ccc2cc(-c3ccc(C(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL357603 Ki 153.0 nM
CCCCCCCCc1ccc(-c2ccc(C(=O)O)c(F)c2)cc1 CHEMBL524687 pEC50 158.49 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C1(C)CCCCC1 CHEMBL345298 Ki 160.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)c(OC)c2)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4211195 EC50 168.0 nM
CC(C)c1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 CHEMBL155421 Kd 171.0 nM
COc1ccc(C2=Cc3ccc(C(=O)O)cc3OC2)cc1C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL75732 Ki 174.0 nM
CCCOc1cc2c(cc1/C(C)=C\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C CHEMBL109581 EC50 192.0 nM
CC(C)(C)c1cc(-c2ccc3cc(C(=O)O)ccc3c2)ccc1O CHEMBL74218 Ki 200.0 nM
CC1(C)CC(=O)Nc2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL306999 EC50 200.0 nM
C/C(=C\c1ncc(C(=O)O)s1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL328481 EC50 200.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCO2 CHEMBL21518 EC50 200.0 nM
CC(/C=C/C1CC1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O CHEMBL69091 EC50 200.0 nM
CC(/C=C/[C@]12CCC[C@@]1(c1ccc3c(c1)C(C)(C)CCC3(C)C)C2)=C\C(=O)O CHEMBL310047 EC50 209.0 nM
CC1=C(CC/C(C)=C/c2ccc(C(=O)O)cc2)C(C)(C)CCC1 CHEMBL36718 EC50 210.0 nM
Cc1cc2c(cc1-c1ncc(-c3ccc(C(=O)O)cc3)s1)C(C)(C)CCC2(C)C CHEMBL25038 AC50 220.0 nM
CC(/C=C/C=C(\C)c1ccc2c(C)ccc(C)c2c1)=C\C(=O)O CHEMBL158064 Relative IC50 227.0 nM
CC(/C=C/C=C(\C)c1ccc2c(c1)C(C)(C)CO2)=C\C(=O)O CHEMBL340495 EC50 230.0 nM
Cc1ccc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL48353 Relative EC30 240.0 nM
CC1(C)CC=C(c2cccc(O)c2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL346429 Kd 254.0 nM
CCCCCCCN1CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 CHEMBL308967 EC50 260.0 nM
C=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL96184 EC50 266.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1cc2c(cc1C(C)C)C(C)(C)CCC2(C)C CHEMBL424636 EC50 270.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2F)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4205304 EC50 279.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)NC2OC(C(=O)O)C(O)C(O)C2O)C(C)(C)CCC1 CHEMBL305760 Ki 280.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCO3)cc1 CHEMBL34464 EC50 330.0 nM
CC1(C)CCC(C)(C)c2cc(Sc3ccc(C(=O)O)cc3)ccc21 CHEMBL119781 EC50 340.0 nM
CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)c(F)c3)ccc21 CHEMBL326911 EC50 350.0 nM
CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1 CHEMBL4210286 EC50 353.0 nM
C=C1C[C@H](c2ccc3c(c2)C(C)(C)CCC3(C)C)[C@@H](/C=C/C(C)=C/C(=O)O)C1 CHEMBL312233 EC50 355.0 nM
C/C(=C\c1ccc(C(=O)O)cn1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL92926 EC50 374.0 nM
CCOC(=O)c1ccc(-c2nc(-c3ccccc3)c(C)s2)cc1 CHEMBL4226012 EC50 383.0 nM
O=C(O)c1ccc2cc(-c3ccc(CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 CHEMBL422490 Ki 386.0 nM
CC(/C=C/CC1(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC1)=C\C(=O)O CHEMBL89581 EC50 391.0 nM
C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1F)C(C)(C)CCC2(C)C CHEMBL330593 EC50 397.0 nM
CC(/C=C/C1(c2ccc3c(c2)C(C)(C)CCC3(C)C)CC1)=C\C(=O)O CHEMBL93518 EC50 399.0 nM
COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CO3)cc1 CHEMBL37672 EC50 400.0 nM
COC(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 CHEMBL78835 Kd 400.0 nM
Cc1cc(C)cc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)c1 CHEMBL155325 Kd 408.0 nM
COCCOCOc1ccc(-c2ccc(C(=O)O)cc2Cl)cc1-c1ccc2c(c1)C(C)(C)CCC2(C)C CHEMBL4203950 EC50 422.0 nM
COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1C(C)(C)C CHEMBL146092 Ki 426.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CO2 CHEMBL120759 EC50 460.0 nM
Cc1cc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1C CHEMBL297022 Relative EC30 480.0 nM
CN1c2cc3c(cc2N=C(c2ccc(C(=O)O)cc2)c2ccc4ccccc4c21)C(C)(C)CCC3(C)C CHEMBL298373 Ki 490.0 nM
CCCCOCCOc1nc(-c2ccc(C(=O)O)c(F)c2)sc1C CHEMBL198997 pEC50 501.19 nM
CC(C)(C)c1cc(C2=Cc3ccc(C(=O)O)cc3OC2)cc(C(C)(C)C)c1O CHEMBL308170 Ki 531.0 nM
C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)C1CCC2C1 CHEMBL40007 EC50 550.0 nM
CCCCCCNC(=O)COc1nc(-c2ccc(C(=O)O)cc2)sc1C CHEMBL472238 pEC50 630.96 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)NC2OC(CO)C(O)C(O)C2O)C(C)(C)CCC1 CHEMBL66228 Ki 710.0 nM
O=C(O)c1ccc(-n2nc(Oc3c(Cl)cccc3Cl)c3c(F)cccc32)cc1 CHEMBL3894222 IC50 800.0 nM
CC1(C)CCC(C)(C)c2cc([C@H](O)c3ccc4cc(C(=O)O)ccc4c3)ccc21 CHEMBL80992 Kd 816.0 nM
O=C(O)c1ccc(-c2ccc(-c3cc4c(Cl)ccc(Cl)c4o3)[nH]2)cc1 CHEMBL46229 Relative EC30 820.0 nM
Cc1ccc(C)c2sc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc12 CHEMBL100439 Relative EC30 840.0 nM
CCOC(=O)c1ccc(-c2nc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)c(C)s2)cc1 CHEMBL4226854 EC50 847.2 nM
CC1(C)CCOc2ccc(-c3ccc4cc(C(=O)O)ccc4c3)cc21 CHEMBL342051 Ki 860.0 nM
Cc1cc(C)c2oc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)cc2c1 CHEMBL100131 Relative EC30 890.0 nM
C/C(=C\c1cc(C(=O)O)cs1)c1cc2c(cc1C)C(C)(C)CCC2(C)C CHEMBL93628 EC50 979.0 nM
Cc1cccc2cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)oc12 CHEMBL98263 Relative EC30 1000.0 nM
Cc1cc2c(cc1-c1cccc(-c3ccc(C(=O)O)cc3)n1)C(C)(C)CCC2(C)C CHEMBL428708 AC50 1000.0 nM