O=C(O)c1cnncc1NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3359024 IC50 0.121 nM
O=C(O)c1ccccc1NC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL1230001 IC50 0.155 nM
O=C(O)c1cnccc1NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3359022 IC50 0.179 nM
Cc1cc(NC(=O)N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)c(C(=O)O)cn1 CHEMBL3359023 IC50 0.235 nM
O=C(O)c1cc(F)ccc1NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3359017 IC50 0.285 nM
O=C(O)c1ccccc1NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3359014 IC50 0.294 nM
O=C(O)c1cc(Cl)ccc1NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3359019 IC50 0.34 nM
O=C(O)c1ccccc1NC(=O)N1C[C@H]2CC(c3ccccc3C(F)(F)F)=C[C@H]2C1 CHEMBL3359015 IC50 0.481 nM
CN(CCOc1ccccc1C(C)(C)C)C(=O)Nc1ccccc1C(=O)O CHEMBL3359005 IC50 0.554 nM
O=C(O)[C@@H](NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1)c1ccccc1 CHEMBL3359028 IC50 0.829 nM
CS(=O)(=O)c1ccc(NC(=O)N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)c(C(=O)O)c1 CHEMBL3359020 IC50 1.55 nM
N#CN1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3983972 IC50 1.619 nM
CN(CCOc1ccccc1C(F)(F)F)C(=O)Nc1ccccc1C(=O)O CHEMBL3358470 IC50 2.65 nM
Cc1ccc2nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)cn2n1 CHEMBL4462481 IC50 2.66 nM
CCOc1ccc2nnc(C(=O)N3C[C@H]4C[C@@H](c5ccccc5C(F)(F)F)C[C@H]4C3)n2c1 CHEMBL4472596 IC50 2.7 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3967849 IC50 2.824 nM
O=C(c1nccs1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288340 IC50 3.0 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)n2c1 CHEMBL3961492 IC50 3.104 nM
O=C(O)C(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3358466 IC50 3.13 nM
Cc1cc(C(N)=O)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593524 IC50 3.3 nM
O=C(c1nnc2ccc(C(F)(F)F)cn12)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL4546092 IC50 3.4 nM
N#CN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3890586 IC50 3.447 nM
O=C(c1cn2nc(C3CC3)ccc2n1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4469381 IC50 3.6 nM
COc1ccc2nnc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n2c1 CHEMBL4452483 IC50 3.7 nM
Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2ccccc21 CHEMBL4532832 IC50 3.71 nM
O=C(c1nnc2ccc(C(F)(F)F)cn12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4468564 IC50 3.75 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)c2c[nH]cn2)CC1 CHEMBL3644466 IC50 3.8 nM
COC(=O)c1cc(C)nc(N2C[C@@H]3CN(c4ccccc4C(F)(F)F)C[C@@H]3C2)n1 CHEMBL3594229 IC50 3.9 nM
Cc1ccc2nnc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n2c1 CHEMBL4524379 IC50 3.9 nM
O=C(NS(=O)(=O)c1ccccc1)c1ccccc1NC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3358465 IC50 3.94 nM
CCOc1ccc2nnc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n2c1 CHEMBL4570619 IC50 3.97 nM
O=C(c1nnc2ccc(Cl)cn12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4457361 IC50 4.01 nM
COC(=O)c1cc(C)nc(N2CCC(c3ccccc3C(F)(F)F)CC2)n1 CHEMBL3594225 IC50 4.1 nM
O=C(c1nnc2ccc(F)cn12)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL4559814 IC50 4.1 nM
O=C(c1nn(C2COC2)c2cc(F)ccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4514302 IC50 4.12 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n2c1 CHEMBL3954871 IC50 4.128 nM
O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3964999 IC50 4.345 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3892353 IC50 4.457 nM
O=C(c1nnc2ccc(Cl)cn12)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL4586625 IC50 4.5 nM
O=C(c1nnc2ccc(F)cn12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4470444 IC50 4.55 nM
O=C(c1n[nH]c2cc(F)ccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4457350 IC50 4.71 nM
O=C(c1n[nH]c2ccc(F)cc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4439759 IC50 4.71 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cccc(Cl)c4C(F)(F)F)CC3)n2c1 CHEMBL3960081 IC50 4.825 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)n[nH]c2C1 CHEMBL3952810 IC50 4.842 nM
CC(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3920137 IC50 4.846 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cc(F)ccc4C(F)(F)F)CC3)n2c1 CHEMBL3901852 IC50 4.88 nM
O=C(c1cn2ncccc2n1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4435017 IC50 4.98 nM
CC(C)(C)c1ccccc1OC1CCN(C(=O)c2ccccn2)CC1 CHEMBL3642671 IC50 5.0 nM
N#CN1CCc2c(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)n[nH]c2C1 CHEMBL3947452 IC50 5.121 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n2c1 CHEMBL4463039 IC50 5.14 nM
CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cc(F)ccc4C(F)(F)F)CC3)c2C1 CHEMBL3900239 IC50 5.244 nM
C[C@H](NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1)C(=O)O CHEMBL3359026 IC50 5.26 nM
O=C(NS(=O)(=O)C1CC1)c1ccccc1NC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3358464 IC50 5.31 nM
CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3920346 IC50 5.356 nM
O=C(c1n[nH]c2c(Cl)cccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4588529 IC50 5.47 nM
O=C(c1n[nH]c2c1CCN(C1COC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3955373 IC50 5.481 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cc(Cl)ccc4C(F)(F)F)CC3)n2c1 CHEMBL3931353 IC50 5.743 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4c(F)cccc4C(F)(F)F)CC3)n2c1 CHEMBL3942071 IC50 5.84 nM
O=C(c1n[nH]c2c1CCN(C1COC1)C2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3976716 IC50 5.906 nM
COc1ccc2nnc(C(=O)N3C[C@H]4C[C@@H](c5ccccc5C(F)(F)F)C[C@H]4C3)n2c1 CHEMBL4525563 IC50 6.0 nM
N#Cc1ccc2nnc(C(=O)N3C[C@H]4C[C@@H](c5ccccc5C(F)(F)F)C[C@H]4C3)n2c1 CHEMBL4569872 IC50 6.0 nM
CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cc(F)ccc4Cl)CC3)c2C1 CHEMBL3913804 IC50 6.171 nM
O=C(c1noc2ccccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4591437 IC50 6.28 nM
COC(=O)c1cc(C)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3594231 IC50 6.3 nM
COc1ccc2nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)cn2n1 CHEMBL4476117 IC50 6.36 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3916885 IC50 6.361 nM
O=C(c1n[nH]c2ccccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4539552 IC50 6.42 nM
O=C(c1cn2nc(N3CCOCC3)ccc2n1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4467672 IC50 6.74 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)n2c1 CHEMBL3949623 IC50 6.75 nM
CS(=O)(=O)NC(=O)c1ccccc1NC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3358463 IC50 6.8 nM
O=C(O)CNC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3359025 IC50 6.82 nM
O=C(c1nc2ccccc2[nH]1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4571698 IC50 6.82 nM
CCN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3956508 IC50 6.886 nM
CCN1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3971149 IC50 6.949 nM
COCCN1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3927372 IC50 6.957 nM
O=C(c1n[nH]c2ccc(Cl)cc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4462736 IC50 6.99 nM
COC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3979697 IC50 7.058 nM
O=C(c1n[nH]c2c1CCN(CCC(F)(F)F)C2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3892799 IC50 7.397 nM
COC(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3963894 IC50 7.438 nM
Cc1cc(-c2nnn[nH]2)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593525 IC50 7.5 nM
CNC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3956948 IC50 7.5 nM
O=C(c1n[nH]c2cc(Cl)ccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4444809 IC50 7.53 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4cc(F)ccc4Cl)CC3)n2c1 CHEMBL3983617 IC50 7.566 nM
N#CN1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3902904 IC50 7.78 nM
CCN1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3939236 IC50 7.802 nM
COCCN1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3929712 IC50 7.957 nM
O=C(c1n[nH]c2c1CN(CCC(F)(F)F)CC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3890367 IC50 8.001 nM
CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)cc4C(F)(F)F)CC3)c2C1 CHEMBL3918927 IC50 8.057 nM
O=C(c1onc2ccccc12)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4458528 IC50 8.26 nM
CCN1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3941905 IC50 8.309 nM
O=C(O)[C@H](NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1)c1ccccc1 CHEMBL3359029 IC50 8.34 nM
O=C(O)c1ccccc1NC(=O)N1CC(c2ccccc2C(F)(F)F)C1 CHEMBL3359011 IC50 8.38 nM
O=C(c1nc2ccccc2o1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4459235 IC50 8.5 nM
CN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3933548 IC50 8.569 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)cc4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3946748 IC50 8.633 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4cc(F)ccc4Cl)CC3)n[nH]c2C1 CHEMBL3900265 IC50 8.831 nM
O=C(c1n[nH]c2c1CN(C1COC1)CC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3905992 IC50 8.838 nM
CC(C)C(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3903764 IC50 8.841 nM
N#Cc1ccc2nnc(C(=O)N3CCC(c4ccc(F)cc4C(F)(F)F)CC3)n2c1 CHEMBL3955453 IC50 9.06 nM
C[C@@H](NC(=O)N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1)C(=O)O CHEMBL3359027 IC50 9.19 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4cc(F)ccc4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3928209 IC50 9.283 nM
O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3926355 IC50 9.387 nM
O=C(c1n[nH]c2c1CCN(C1COC1)C2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3973204 IC50 9.495 nM
CCn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2ccc(F)cc21 CHEMBL4583814 IC50 9.54 nM
O=C(O)c1cc(C(F)(F)F)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3594234 IC50 9.6 nM
O=C(c1nc2ccccc2s1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4573203 IC50 9.61 nM
COC(=O)c1cc(C)nc(N2CCN(c3ccccc3C(F)(F)F)CC2)n1 CHEMBL3594227 IC50 9.7 nM
O=C(c1cn2ccccc2n1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4452180 IC50 9.71 nM
CC(C)(C)c1ccccc1SC1CN(C(=O)c2ccccn2)C1 CHEMBL3642669 IC50 10.0 nM
O=C(c1n[nH]c2c1CN(CC1CC1)CC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3973745 IC50 10.0 nM
CNS(=O)(=O)c1ccc2nnc(C(=O)N3C[C@H]4C[C@@H](c5ccccc5C(F)(F)F)C[C@H]4C3)n2c1 CHEMBL4593080 IC50 10.0 nM
COC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3954121 IC50 10.12 nM
CNC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3918411 IC50 10.22 nM
CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)c2C1 CHEMBL3984801 IC50 10.27 nM
CNC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3911097 IC50 10.29 nM
O=C(c1n[nH]c2c1CCN(CCC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3950807 IC50 10.71 nM
O=C(c1n[nH]c2c1CN(CCC(F)(F)F)CC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3907224 IC50 10.78 nM
O=C(c1cn2nc(N3CCCC3)ccc2n1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4474669 IC50 10.8 nM
O=C(c1n[nH]c2c1CNCC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3976567 IC50 10.87 nM
O=C(c1ccncc1)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3937218 IC50 11.2 nM
COC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3927762 IC50 11.43 nM
CNC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3905537 IC50 11.48 nM
O=C(c1n[nH]c2c1CN(C1COC1)CC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3898193 IC50 11.55 nM
CC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3895633 IC50 11.62 nM
O=C(c1n[nH]c2c1CN(CCC(F)(F)F)CC2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3911188 IC50 11.72 nM
O=C(c1n[nH]c2c1CN(C1COC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3921078 IC50 11.85 nM
CC(C)(C)c1cc(Cl)ccc1OCC1CN(C(=O)C(=O)O)C1 CHEMBL3642678 IC50 12.0 nM
N#CN1CCc2c(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3930208 IC50 12.0 nM
O=C(c1n[nH]c2c1CN(CC(F)(F)F)CC2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3939141 IC50 12.17 nM
CCN1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3937518 IC50 12.67 nM
COc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3594235 IC50 12.8 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3594232 IC50 12.8 nM
COC(=O)N1CCc2c(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3983679 IC50 12.84 nM
O=C(c1n[nH]c2c1CCNC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3944575 IC50 13.33 nM
O=C(c1n[nH]c2c1CN(CC1CC1)CC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3931606 IC50 13.44 nM
O=C(c1n[nH]c2c1CN(CC1CC1)CC2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3941418 IC50 13.57 nM
O=C(c1n[nH]c2c1CN(CCC(F)(F)F)CC2)N1CCC(c2cc(F)cc(F)c2C(F)(F)F)CC1 CHEMBL3912585 IC50 13.78 nM
O=C(c1n[nH]c2c1CCNC2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3981399 IC50 14.04 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)c1 CHEMBL3593526 IC50 14.1 nM
O=C(c1n[nH]c2c1CN(CC1CC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3909579 IC50 14.33 nM
CC(C)(C)CN1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3893177 IC50 14.36 nM
CN(C)C(=O)Nc1ccc2nnc(C(=O)N3C[C@H]4C[C@@H](c5ccccc5C(F)(F)F)C[C@H]4C3)n2c1 CHEMBL4536181 IC50 14.6 nM
COCCN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3949536 IC50 14.63 nM
CCC(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3981206 IC50 14.72 nM
COCCN1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3947844 IC50 14.93 nM
O=C(c1n[nH]c2c1CCN(CC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3925278 IC50 14.99 nM
CC(C)(C)c1cc(Cl)ccc1OC1CN(C(=O)c2ccccn2)C1 CHEMBL3642675 IC50 15.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)c2nc[nH]n2)CC1 CHEMBL3644477 IC50 15.0 nM
CC(C)CC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3912776 IC50 15.05 nM
CCN1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)c2C1 CHEMBL3932584 IC50 15.29 nM
N#CN1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3932482 IC50 15.42 nM
COCCN1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)c2C1 CHEMBL3921969 IC50 15.54 nM
O=C(c1n[nH]c2c1CN(C1COC1)CC2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3938065 IC50 15.57 nM
O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3903652 IC50 15.87 nM
COCCN1CCc2[nH]nc(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3934166 IC50 15.88 nM
O=C(c1cc2ccccc2[nH]1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4549656 IC50 15.9 nM
O=C(c1ccccn1)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3949538 IC50 16.03 nM
N#CN1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3947659 IC50 16.42 nM
O=C(c1n[nH]c2c1CCN(C1COC1)C2)N1CCC(c2cc(F)cc(F)c2C(F)(F)F)CC1 CHEMBL3931264 IC50 16.42 nM
CC(C)(C)CN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3961659 IC50 16.99 nM
COc1ccc(Cl)cc1NC(=O)N1CCN(c2ccccc2C(F)(F)F)CC1 CHEMBL3288142 IC50 17.0 nM
Cn1cnc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c1 CHEMBL3288337 IC50 17.0 nM
CCC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3904444 IC50 17.05 nM
O=C(c1n[nH]c2c1CN(CC(F)(F)F)CC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3935172 IC50 17.07 nM
COC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)n[nH]c2C1 CHEMBL3977779 IC50 17.09 nM
O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2cc(F)cc(F)c2C(F)(F)F)CC1 CHEMBL3903293 IC50 17.2 nM
CNC(=O)N1CCc2c(C(=O)N3CCC(c4cc(F)cc(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3940885 IC50 17.84 nM
CC(C)C(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3911192 IC50 17.88 nM
COC(=O)c1ccccc1NC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288342 IC50 18.0 nM
O=C(c1n[nH]c2c1CCN(CC(F)(F)F)C2)N1CCC(c2cc(F)cc(F)c2C(F)(F)F)CC1 CHEMBL3933566 IC50 18.36 nM
O=C(c1n[nH]c2c1CN(C(=O)N1CCCCC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3963373 IC50 18.38 nM
O=C(O)CN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3915294 IC50 18.87 nM
O=C(c1cccnc1)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3953490 IC50 18.92 nM
CC(C)CC(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3901308 IC50 19.35 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4c(F)cccc4C(F)(F)F)CC3)n[nH]c2C1 CHEMBL3914073 IC50 19.44 nM
CNC(=O)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3938457 IC50 19.62 nM
CC(C)(C)c1cc(F)ccc1OC1CN(C(=O)c2ccccn2)C1 CHEMBL3642665 IC50 20.0 nM
CC(C)(C)c1cc(F)ccc1OC1CN(C(=O)CCC(=O)O)C1 CHEMBL3642672 IC50 20.0 nM
O=C(c1n[nH]c2c1CN(C(=O)N1CCCC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3951726 IC50 20.39 nM
O=C(c1n[nH]c2c1CCNC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3936783 IC50 20.74 nM
O=C(O)c1ccnc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3594233 IC50 20.8 nM
COc1ccc2nnc(C(=O)N3CCC(c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)n2c1 CHEMBL3929538 IC50 21.63 nM
O=C(c1ccccc1)N1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3975444 IC50 21.66 nM
CC(C)(C)CN1Cc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3920209 IC50 22.48 nM
COc1ccc(Cl)cc1NC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288331 IC50 23.0 nM
O=C(O)c1cnnc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)c1 CHEMBL3593534 IC50 23.0 nM
CC(C)(C)c1cc(F)ccc1OCC1CN(C(=O)CC(=O)O)C1 CHEMBL3642674 IC50 23.0 nM
O=C(c1n[nH]c2c1CN(CC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3920509 IC50 23.39 nM
FC(F)(F)c1cccc(CN2CCN(c3ncnc4sc5c(c34)CCC5)CC2)c1 CHEMBL3288146 IC50 24.0 nM
CC(C)(C)c1ccccc1OC1CN(C(=O)C2(C(=O)O)CC2)C1 CHEMBL3642668 IC50 24.0 nM
O=C(c1n[nH]c2c1CN(CCC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3920042 IC50 25.17 nM
O=C(c1n[nH]c2c1CNC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3905828 IC50 26.85 nM
FC(F)(F)c1ccnc(N2CCC(c3ccccc3C(F)(F)F)CC2)n1 CHEMBL3288336 IC50 28.0 nM
Cc1sc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)nc1C(=O)O CHEMBL3593535 IC50 29.3 nM
O=C(c1cc2ncccc2[nH]1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4463938 IC50 29.8 nM
CC(C)(C)c1cc(Br)ccc1N1CCN(C(=O)CC(=O)O)CC1 CHEMBL3644478 IC50 30.0 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4cccnc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593693 IC50 31.1 nM
O=C(O)c1ccc2nnc(C(=O)N3C[C@H]4C[C@@H](c5ccccc5C(F)(F)F)C[C@H]4C3)n2c1 CHEMBL4451481 IC50 32.8 nM
O=C(c1n[nH]c2c1CN(C(=O)N1CCNCC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 CHEMBL3946309 IC50 33.04 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4cc(F)ccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593536 IC50 33.4 nM
CC(C)(C)c1cc(F)ccc1OCC1CCN(C(=O)CC(=O)O)C1 CHEMBL3642679 IC50 34.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)C(=O)C2NC(=O)NC2=O)CC1 CHEMBL3644480 IC50 34.0 nM
Cc1cc(C(=O)O)nc(N2CCC(c3ccccc3C(F)(F)F)CC2)n1 CHEMBL3594226 IC50 35.3 nM
CC(C)(C)c1ccccc1OC1CN(C(=O)CC(=O)O)C1 CHEMBL3642666 IC50 36.0 nM
COC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)c2C1 CHEMBL3971494 IC50 36.23 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)C(=O)O)CC1 CHEMBL3644473 IC50 38.0 nM
CC(C)(C)c1ccccc1OCC1CCN(C(=O)CC(=O)O)C1 CHEMBL3642677 IC50 40.0 nM
Cc1nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)ncc1C(=O)O CHEMBL3594239 IC50 40.8 nM
O=C(O)c1cccnc1N1C[C@H]2C[C@@H](c3ccccc3C(F)(F)F)C[C@H]2C1 CHEMBL3593532 IC50 43.8 nM
COc1ccc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2c1 CHEMBL4591895 IC50 44.6 nM
Cc1nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)nc(C(=O)O)c1C CHEMBL3594237 IC50 48.8 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(-c3noc(=O)[nH]3)cc2)CC1 CHEMBL3644469 IC50 49.0 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4cnccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593540 IC50 51.8 nM
O=C(c1ccco1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288341 IC50 52.0 nM
Cc1cc(C(=O)O)cc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593527 IC50 53.3 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)CC(=O)O)CC1 CHEMBL3644468 IC50 54.0 nM
Cc1cc(C(=O)O)nc(N2C[C@@H]3CN(c4ccccc4C(F)(F)F)C[C@@H]3C2)n1 CHEMBL3594230 IC50 57.4 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)Nc2ccccc2)CC1 CHEMBL3644475 IC50 58.0 nM
O=C(Cc1ccccc1C(F)(F)F)N1CCN(c2ncnc3sc4c(c23)CCC4)CC1 CHEMBL3288147 IC50 60.0 nM
Cc1cc(C(N)=O)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4759066 IC50 62.0 nM
Cc1cc(C(=O)NC2CC2)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4755863 IC50 62.0 nM
O=C(c1n[nH]c2c1CNCC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 CHEMBL3966545 IC50 62.51 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)CCC(=O)NS(C)(=O)=O)CC1 CHEMBL3644474 IC50 64.0 nM
Cc1cc(C(=O)O)nc(N2CC[C@@H](COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4748473 IC50 65.0 nM
Cc1ccc(C(=O)O)c(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593531 IC50 68.4 nM
CC(C)(C)c1cc(Cl)ccc1OC1CN(C(=O)CCC(=O)O)C1 CHEMBL3642676 IC50 71.0 nM
O=C(c1cnccc1C(F)(F)F)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288335 IC50 76.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4746217 IC50 80.0 nM
Cc1cc(C(=O)NS(C)(=O)=O)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4752884 IC50 81.0 nM
O=C(O)c1cccc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)c1 CHEMBL3593530 IC50 83.2 nM
O=C(c1cc2ccncc2[nH]1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL4586278 IC50 84.2 nM
Cc1cc(-c2nn[nH]n2)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4776400 IC50 86.0 nM
CNC(=O)c1cc(C)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4751437 IC50 89.0 nM
Cc1cc(C(=O)O)nc(N2CCN(c3ccccc3C(F)(F)F)CC2)n1 CHEMBL3594228 IC50 89.5 nM
Cc1cnc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)nc1C(=O)O CHEMBL3594238 IC50 90.1 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)C23CC4CC(CC(C(=O)O)(C4)C2)C3)CC1 CHEMBL3644482 IC50 95.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)Nc2ccc(N(C)C)cc2)C(C)(C)CCC1 CHEMBL1802450 Kd(app) 98.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288339 IC50 120.0 nM
CC(C)n1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2ccc(F)cc21 CHEMBL4525347 IC50 128.0 nM
COc1ccc(Cl)cc1NC(=O)N1CCN(c2ncccc2C(F)(F)F)CC1 CHEMBL3288136 IC50 130.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3ccccc3C(C)(C)C)C2)n1 CHEMBL4745145 IC50 130.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3cc(F)ccc3C(F)(F)F)C2)n1 CHEMBL4761230 IC50 130.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3ccccc3C(F)(F)F)C2)c1 CHEMBL4761138 IC50 130.0 nM
COC(=O)COc1ccc(NC(=O)/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)cc1 CHEMBL1801542 Kd(app) 131.0 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4cccc(F)c4Cl)C[C@H]3C2)n1 CHEMBL3593539 IC50 137.0 nM
CN(CCOc1ccc(F)cc1C(C)(C)C)C(=O)Nc1ccccc1C(=O)O CHEMBL3359006 IC50 140.6 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)NCCO)C(C)(C)CCC1 CHEMBL60405 EC50 145.0 nM
CC(=O)N1CCc2c(C(=O)N3CCC(c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)n[nH]c2C1 CHEMBL3892497 IC50 149.44 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)C2(C(=O)O)CC2)CC1 CHEMBL3644479 IC50 150.0 nM
Cc1cc(C(=O)O)nc(N2CC[C@H](COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4753780 IC50 150.0 nM
CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)c2C1 CHEMBL3905075 IC50 150.2 nM
CC(C)c1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3594236 IC50 153.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)N2CCOCC2)C(C)(C)CCC1 CHEMBL1802454 EC50 154.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1 CHEMBL7301 Kd(app) 156.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3ccccc3C3CCCC3)C2)n1 CHEMBL4762942 IC50 160.0 nM
O=C(O)c1cncc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593533 IC50 166.0 nM
COc1ccc(NC(=O)N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)c(C(=O)O)c1 CHEMBL3359018 IC50 170.3 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)NCC(O)CO)C(C)(C)CCC1 CHEMBL1803043 EC50 171.0 nM
O=C(O)c1cnc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)nc1 CHEMBL3593523 IC50 171.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3cccc(Cl)c3C(F)(F)F)C2)n1 CHEMBL4753163 IC50 180.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1 CHEMBL986 Kd(app) 182.0 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4cccc(F)c4C(F)(F)F)C[C@H]3C2)n1 CHEMBL3593537 IC50 196.0 nM
CC(C)(C)c1ccccc1OC1CN(C(=O)CCC(=O)O)C1 CHEMBL3642667 IC50 210.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3ccccc3C3CCCCC3)C2)n1 CHEMBL4780787 IC50 210.0 nM
Cc1cc(C(=O)O)nc(N2CCC(CSc3ccccc3C(F)(F)F)C2)n1 CHEMBL4743933 IC50 230.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3ccc(F)cc3C(F)(F)F)C2)n1 CHEMBL4753628 IC50 240.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C\C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1 CHEMBL58106 EC50 245.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(OCC3CCNCC3)cc2)CC1 CHEMBL3644472 IC50 250.0 nM
Cc1cc(C(=O)O)nc(N2CCC3(CCN(c4ccccc4C(F)(F)F)C3)C2)n1 CHEMBL4753917 IC50 260.0 nM
CC(C)(C)c1ccccc1S(=O)(=O)C1CN(C(=O)c2ccccc2)C1 CHEMBL3642670 IC50 290.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)Cc2nnn[nH]2)CC1 CHEMBL3644476 IC50 300.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3c(F)cccc3C(F)(F)F)C2)n1 CHEMBL4782306 IC50 300.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)C(O)CO)CC1 CHEMBL3644481 IC50 330.0 nM
Cc1cc(C(=O)O)nc(N2C[C@H]3C[C@@H](c4cc(F)ccc4Cl)C[C@H]3C2)n1 CHEMBL3593538 IC50 347.0 nM
COc1ccc(Cl)cc1NC(=O)N1CCN(c2ncccc2C(F)(F)F)CC1C CHEMBL3288149 IC50 350.0 nM
COc1ccc(Cl)cc1NC(=O)N1CCN(c2ncnc3sc4c(c23)CCC4)CC1 CHEMBL3288143 IC50 360.0 nM
O=C(c1n[nH]c2c1CNCC2)N1CCC(c2cccc(F)c2Cl)CC1 CHEMBL3914828 IC50 424.16 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)C(=O)NS(=O)(=O)NCC2CC2)CC1 CHEMBL3644471 IC50 430.0 nM
O=C(c1cn(Cc2ccccc2)cn1)N1CCN(c2ccccc2Cl)CC1 CHEMBL3288135 IC50 440.0 nM
COc1ccc(Cl)cc1NC(=O)N1CCCN(c2ncccc2C(F)(F)F)CC1 CHEMBL3288330 IC50 480.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(C(=O)O)cc2)CC1 CHEMBL3644470 IC50 480.0 nM
Cc1cc(C(=O)O)nc(N2CCCC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4754017 IC50 480.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3cnccc3C(F)(F)F)C2)n1 CHEMBL4786892 IC50 520.0 nM
CC(C)(C)c1ccccc1N1CCN(C(=O)NCC(=O)O)CC1 CHEMBL3644467 IC50 540.0 nM
Cn1cncc1C(=O)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288338 IC50 550.0 nM
Cc1ccc(N2C[C@H]3C[C@@H](c4ccccc4C(F)(F)F)C[C@H]3C2)nc1C(=O)O CHEMBL3593528 IC50 584.0 nM
COC(=O)c1cccc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c1 CHEMBL3288334 IC50 600.0 nM
Cc1cc(C(=O)O)nc(N2CCC(COc3cccnc3C(F)(F)F)C2)n1 CHEMBL4759728 IC50 660.0 nM
O=C(O)c1cccnc1N1CCC(COc2ccccc2C(F)(F)F)C1 CHEMBL4784583 IC50 680.0 nM
CCCCCS(=O)(=O)NC(=O)C(=O)N1CCC(COc2ccccc2C(C)(C)C)CC1 CHEMBL3642673 IC50 790.0 nM
Cc1cc(C(=O)O)nc(N2CC(COc3ccccc3C(F)(F)F)C2)n1 CHEMBL4759603 IC50 800.0 nM
COc1ccc(Cl)cc1C(=O)N1CCN(c2ncnc3sc4c(c23)CCC4)C(C)C1 CHEMBL3288150 IC50 830.0 nM
COc1ccc(Cl)cc1NC(=O)N1CCN(c2ccccc2Cl)CC1 CHEMBL3288141 IC50 890.0 nM
Cc1cc(C(=O)O)nc(N2CCC(CNc3ccccc3C(F)(F)F)C2)n1 CHEMBL4755495 IC50 900.0 nM
O=C(c1cccc(C(F)(F)F)c1)N1CCC(c2ccccc2C(F)(F)F)CC1 CHEMBL3288333 IC50 920.0 nM