NCCc1ccc(O)c(O)c1 CHEMBL59 Potency 0.0316 nM
O=C(/N=C1\SCC(=O)N1c1ccccc1Cl)c1ccco1 CHEMBL3197851 Potency 0.2 nM
O=C(N/N=C/c1sc(N2CCCCC2)nc1-c1cccs1)c1cccnc1 CHEMBL3193084 Potency 0.6 nM
COc1ccc(S(=O)(=O)NC(CC(=O)NCc2ccc3c(c2)OCO3)c2ccco2)cc1 CHEMBL1458236 Potency 0.9 nM
CCCCC[C@H](CC(=O)NO)C(=O)N[C@H](C(=O)N1CCC[C@H]1CO)C(C)C CHEMBL308333 Potency 1.0 nM
Cc1ccc(C(=O)OCC(=O)NC2CCCCC2)s1 CHEMBL1383575 Potency 10.0 nM
CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)CSc1nncs1 CHEMBL1367444 Potency 15.8 nM
O=C(c1sc2cc(F)ccc2c1Cl)N1CCN(c2ccccc2)CC1 CHEMBL1445279 Potency 20.0 nM
CC1CCCC(C)N1C(=O)C1CCCCC1 CHEMBL1427696 Potency 22.4 nM
CCOc1ccc(CO/N=C/c2c(C)nc(O)nc2O)cc1 CHEMBL3212668 Potency 22.4 nM
CCCn1c(C)cc(C(=O)COC(=O)c2cc(S(=O)(=O)NCC(C)C)c(Cl)cc2Cl)c1C CHEMBL1373063 Potency 25.1 nM
CCC(=O)NCCCOc1ccccc1 CHEMBL1374949 Potency 25.1 nM
Nc1nc(N)c(N=Nc2ccc(Cl)cc2)c(O)n1 CHEMBL1565317 Potency 25.1 nM
Cc1cc(C)nc(NC(=O)c2c(C(=O)O)noc2C)n1 CHEMBL1502893 Potency 25.1 nM
CCOc1ccc(Cc2c(Cl)nc(SC)nc2OC)cc1 CHEMBL1439221 Potency 25.1 nM
O=C(NC(=S)NCCc1ccccc1)C1CCCCC1 CHEMBL1608986 Potency 25.1 nM
Cc1cc(C(C)(C)C)ccc1OCCCCN1CCCC1 CHEMBL1526090 Potency 25.1 nM
Clc1cccc(N/N=C/c2ccc(N3CCOCC3)cc2)c1 CHEMBL3208086 Potency 25.1 nM
COc1ccc(S(=O)(=O)Nc2ccccc2OC)cc1NC(=O)CC1CC2CCC1C2 CHEMBL1417273 Potency 25.1 nM
CCOc1ccc(NC(=O)CSc2nnc(C3CC3)n2N)cc1 CHEMBL1573985 Potency 25.1 nM
CC(OC(=O)Cc1coc2ccc3ccccc3c12)C(=O)Nc1ncc(Cl)cc1Cl CHEMBL1348698 Potency 25.1 nM
c1ccc(CN2CCN(c3[nH]cnc4ncnc3-4)CC2)cc1 CHEMBL1418131 Potency 25.1 nM
CSC1=NCCN1CCOc1ccccc1 CHEMBL1311130 Potency 25.1 nM
Nc1cccc2c(=O)[nH]ccc12 CHEMBL446240 Potency 25.1 nM
Clc1ccc(SCc2cn3cccnc3n2)cc1 CHEMBL1372612 Potency 28.2 nM
CCOC(=O)C1=C(CN2CCC(C)CC2)NC(=O)NC1c1ccc(Cl)cc1 CHEMBL1578026 Potency 28.2 nM
COc1ccc(OC)c(C2=[N+]([O-])C(C)(C)C(C)(C)[N+]([O-])=C2)c1 CHEMBL1491039 Potency 28.2 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(N)=S CHEMBL77030 Potency 28.2 nM
COCc1ccc(CN2CCCC(C(=O)c3sccc3C)C2)o1 CHEMBL1334855 Potency 28.2 nM
O=S(=O)(NCc1ccc(Cl)cc1)NCc1ccccc1F CHEMBL1576131 Potency 28.2 nM
CCOc1ccc(Cl)cc1S(=O)(=O)n1nnc2ccccc21 CHEMBL1480560 Potency 28.2 nM
Cc1ccccc1N/C=C/C(=C(C#N)C#N)N(C)C CHEMBL1335249 Potency 28.2 nM
Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL1559 Potency 28.2 nM
Cc1nc(N2CCN(Cc3ccc(Cl)cc3)CC2)c2oc3ccccc3c2n1 CHEMBL1571837 Potency 28.2 nM
O=C(CCn1c(=O)oc2ccccc21)N(Cc1ccccc1)c1ccccc1 CHEMBL1420974 Potency 28.2 nM
CSCCC(NC(=O)C1CCC(C)CC1)C(=O)OCC(=O)c1ccc(Cl)cc1 CHEMBL1599050 Potency 28.2 nM
Clc1ccccc1CN1CCc2sccc2C1 CHEMBL1717 Potency 28.2 nM
COc1cccc(C(=O)Nc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 CHEMBL1521482 Potency 28.2 nM
COc1cccc(CNC(=O)Cc2ccc(-n3c(=O)[nH]c4ccccc4c3=O)cc2)c1 CHEMBL1443429 Potency 28.2 nM
c1ccc2c(c1)CCNC2c1ccncc1 CHEMBL1534809 Potency 28.2 nM
COc1ccc2nc(NC(=O)c3ccoc3C)sc2c1 CHEMBL408850 Potency 28.2 nM
CC(C)C(=O)NC(=S)/C=C1/N(C)c2ccccc2C1(C)C CHEMBL1445414 Potency 28.2 nM
Cc1cc(N2CCN(c3nc(-c4ccccc4)cs3)CC2)c2ccccc2n1 CHEMBL1500912 Potency 28.2 nM
CCCc1cc(O)nc(N=C(NC(=O)C(C)N2C(=O)c3ccccc3C2=O)Nc2ccccc2)n1 CHEMBL1461262 Potency 31.6 nM
CC(=O)n1cc([C@H]2C=C(C(=O)O)O[C@@H](OCCCCO)C2)c2ccccc21 CHEMBL1504207 Potency 31.6 nM
CCc1ccc(-c2csc(NC(=O)COC(=O)CCc3nc4ccccc4s3)n2)cc1 CHEMBL1466446 Potency 31.6 nM
C#CCNC(=O)C1=C[C@@H](C)C[C@@H](OCc2ccc(CO)cc2)O1 CHEMBL1586490 Potency 31.6 nM
Sc1nc(-c2ccc(Br)cc2)cn1CCc1ccccc1 CHEMBL1485734 Potency 31.6 nM
CCN(CC)C(=S)NC(=O)c1ccc(OC)c(Br)c1 CHEMBL1331485 Potency 35.5 nM
CCOC(=O)Cn1c(=O)oc2cc(S(=O)(=O)NCCc3ccc(C)cc3)ccc21 CHEMBL1324333 Potency 35.5 nM
O=C(CSc1nnc2ccccn12)Nc1nsc(-c2ccccc2)n1 CHEMBL1572517 Potency 39.8 nM
Cc1nc(C(=O)NC(C)C)nn1-c1cc(Cl)cc(Cl)c1 CHEMBL1339673 Potency 44.7 nM
CCC(=O)Oc1ccc(/C(CC)=C(\CC)c2ccc(OC(=O)CC)cc2)cc1 CHEMBL1525298 Potency 44.7 nM
O=C(CN(c1ccccn1)S(=O)(=O)c1ccc(F)cc1)Nc1ccccc1 CHEMBL1305903 Potency 44.7 nM
Cc1ccc(C)c(-c2nc3cc(N)ccc3[nH]2)c1 CHEMBL1457008 Potency 44.7 nM
CC(C)c1ccccc1NC(=O)Nc1ccc(F)cc1F CHEMBL1588836 Potency 50.1 nM
O=c1c2ccccc2nnn1CSc1nnc(-c2ccco2)o1 CHEMBL1344317 Potency 56.2 nM
Cc1ccc(S(=O)(=O)NCC(=O)N(CC(=O)NC2CCCCC2)CC2CCCO2)cc1 CHEMBL1471192 Potency 56.2 nM
CC(C)(C)OC(=O)N1CCC(C(=O)N2CCOCC2)CC1 CHEMBL1415967 Potency 56.2 nM
O=C(CSc1nc2ccccc2o1)Nc1nncs1 CHEMBL1405330 Potency 56.2 nM
CC(C)C(=O)Nc1ccc(N2CCN(c3ccc(F)cc3)CC2)cc1 CHEMBL1535879 Potency 56.2 nM
CCS(=O)(=O)NCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2 CHEMBL1360931 Potency 63.1 nM
O=C(Nc1ccccc1)C1CCCN(S(=O)(=O)c2ccc(-n3cnnn3)cc2)C1 CHEMBL1523889 Potency 63.1 nM
C#CCNC(=O)C1=C[C@H](C2CCCCC2)C[C@H](OCCCCO)O1 CHEMBL1451643 Potency 70.8 nM
Cc1cc(O)nc(NCc2ccccc2)n1 CHEMBL1517757 Potency 70.8 nM
CCCn1nnc(NC(=O)C(C)C)n1 CHEMBL1468914 Potency 70.8 nM
COc1ccc(NC(=S)N(CCN(C)C)Cc2cccs2)cc1 CHEMBL1499731 Potency 79.4 nM
C[C@H](NC(=O)c1[nH]cnc1C(=O)N1CCc2ccccc2C1)C(=O)OCc1ccccc1 CHEMBL1449613 Potency 79.4 nM
COC(=O)Cn1/c(=N/C(=O)C2COc3ccccc3O2)sc2cc(S(N)(=O)=O)ccc21 CHEMBL3198785 Potency 89.1 nM
COC(=O)CNC(c1ccccc1)c1cc(Cl)ccc1NC(=O)c1cccc(Cl)c1 CHEMBL1519134 Potency 89.1 nM
CCC(NCCc1c[nH]c2ccccc12)=C1C(=O)N(C)C(=O)N(C)C1=O CHEMBL1510946 Potency 89.1 nM
CCOC(=O)Nc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL1526107 Potency 89.1 nM
COC(=O)[C@@H]1C[C@@]2(O)[C@@H](O)[C@@H](O)[C@@H](O)C[C@H]2N1Cc1cc(OC)cc(OC)c1 CHEMBL1522552 Potency 89.1 nM
CC(=O)N1CCN(CC(=O)Nc2sccc2C#N)CC1 CHEMBL1347763 Potency 89.1 nM
CS(=O)(=O)NCc1ccc(C(=O)NCc2ccccc2)cc1 CHEMBL1427512 Potency 89.1 nM
CC(C)N1CCN(Cc2ccc3nsnc3c2)CC1CCO CHEMBL1507532 Potency 89.1 nM
COc1cccc(CNc2nc3nc(C)c(Cl)c(C)n3n2)c1 CHEMBL1301832 Potency 100.0 nM
O=C(NC(=O)c1ccc(F)cc1)Nc1nc(-c2cccs2)cc(C(F)(F)F)n1 CHEMBL1333151 Potency 100.0 nM
Cc1cc(NC(=O)/C=C/c2cccc(F)c2)n(-c2nc3ccccc3[nH]2)n1 CHEMBL1452723 Potency 100.0 nM
CC(C)(C)N=C(S)NCc1ccc2c(c1)OCO2 CHEMBL1414576 Potency 100.0 nM
Cc1sc2c(c1C)C(=O)NC(c1cccc(O)c1)N2 CHEMBL1345214 Potency 100.0 nM
O=C(Cn1ncc(Cl)c(Cl)c1=O)NCC1CCCCC1 CHEMBL1353015 Potency 100.0 nM
CC(CCc1ccccc1)NC(=O)COC(=O)C1CCC(C(C)(C)C)CC1 CHEMBL1335923 Potency 100.0 nM
CCOC(=O)c1c(NC(C)=O)sc2c(O)c(CN3CCN(CC)CC3)ccc12 CHEMBL1574201 Potency 100.0 nM
Cc1ccc(NC(=O)c2cccc(S(=O)(=O)N(C)c3ccccc3)c2)cc1S(=O)(=O)N1CCOCC1 CHEMBL1507441 Potency 100.0 nM
Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3cnc4scc(C)n4c3=O)cc2)c1C CHEMBL1445396 Potency 100.0 nM
CCCCC1=C([O-])C2N=CC=CC2=[N+](c2ccccn2)C1=O CHEMBL1350798 Potency 100.0 nM
NCCc1nnc(SCc2ccccc2Cl)o1 CHEMBL1311807 Potency 100.0 nM
O=C(OCC1O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL1500249 Potency 112.2 nM
CCN(Cc1ccncc1)C(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 CHEMBL1569332 Potency 112.2 nM
CC(C)CNC(=O)C(=O)N/N=C/c1cccs1 CHEMBL3192501 Potency 112.2 nM
CCN(CC)c1ccc(NC(=O)CSc2nc(O)c3ccccc3n2)cc1 CHEMBL1500713 Potency 112.2 nM
O=C(Cn1c(CC(=O)N2CCCC2)nc2ccccc21)NCc1ccccc1 CHEMBL1343146 Potency 112.2 nM
Cc1sc(NC(=O)C2C3CCC(C3)C2C(=O)O)c(C(N)=O)c1-c1ccc(C(C)(C)C)cc1 CHEMBL1501891 Potency 112.2 nM
O=C(CCn1cnc2ccccc2c1=O)Nc1ccc2c(c1)OCCO2 CHEMBL1488950 Potency 112.2 nM
CCN(CC)c1ccc(C(=O)Nc2cccc(F)c2)cc1 CHEMBL1385176 Potency 112.2 nM
Cc1occc1-c1nnc(SCC(=O)Nc2ccccn2)o1 CHEMBL1478548 Potency 112.2 nM
Cc1nc(N/C(N)=N/C(=O)NC2CCCCC2)nc2ccccc12 CHEMBL546493 Potency 112.2 nM
CCCN(CC1CC1)C(S)=Nc1ccc(Oc2ccccc2)cc1 CHEMBL1510488 Potency 112.2 nM
CSc1nsc(SC)c1NC(=O)OCCc1ccccn1 CHEMBL1560831 Potency 112.2 nM
Cc1c(Cl)cccc1N=C(S)N(Cc1cccnc1)Cc1ccccc1Cl CHEMBL1404718 Potency 112.2 nM
CCOC(=O)C(Cc1ccccc1)(NC(C)=O)C(=O)OCC CHEMBL1573595 Potency 112.2 nM
CN(C)CCSc1nnc2sc3ccccc3n12 CHEMBL1326507 Potency 112.2 nM
Cn1c(C(=O)OCC(=O)NCc2ccco2)cc2sccc21 CHEMBL1338776 Potency 112.2 nM
Cc1ccc(S(=O)(=O)N2CCC(=O)N2)cc1 CHEMBL1546490 Potency 112.2 nM
CN(C)c1ccc(NC(=S)NC(=O)/C=C/c2ccc(Cl)cc2)cc1 CHEMBL1429485 Potency 112.2 nM
O=C(O)C[C@@H]1C(=O)O[C@@H]2C(COC(=O)c3cc(O)c(O)c(O)c3)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H]2OC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1391063 Potency 112.2 nM
CCCCOc1ccc(S(=O)(=O)N2CCCCCC2)cc1 CHEMBL1469625 Potency 112.2 nM
O=C(CS(=O)(=O)c1cccc(C(F)(F)F)c1)Nc1ccccc1Cl CHEMBL1391430 Potency 112.2 nM
CC(C)(C)NC(=O)CSc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 CHEMBL1578350 Potency 125.9 nM
Cc1ccc(Cc2cncc(O)c2)cc1S(=O)(=O)O CHEMBL330756 Potency 125.9 nM
Cc1ccc(N2C(=O)NC(=O)/C(=C\c3ccoc3)C2=O)cc1 CHEMBL1398909 Potency 125.9 nM
CC(C)(C)NCC(O)COc1cccc2c1CC(O)C(O)C2 CHEMBL521606 Potency 125.9 nM
COc1ccc(C2/C(=C(\O)c3ccccc3)C(C)=Nc3nc4ccccc4n32)c(OC)c1 CHEMBL1576863 Potency 125.9 nM
O=C(N/N=C/c1cc2c(cc1Br)OCO2)c1c[nH]c2ccccc12 CHEMBL3191420 Potency 125.9 nM
COc1cccc(OCc2nnc(SCC(=O)NCc3ccco3)n2C)c1 CHEMBL1446628 Potency 125.9 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 Potency 125.9 nM
COC(=O)c1ccccc1NC(=O)C1CC(=O)N(c2ccc(C)cc2)C1 CHEMBL1568039 Potency 125.9 nM
COc1cc(-c2csc(C)n2)ccc1O CHEMBL1489892 Potency 125.9 nM
CCOc1cc(NC(=O)c2cccs2)c(OCC)cc1NC(=O)c1ccco1 CHEMBL1404955 Potency 125.9 nM
COc1cc(OC)c2c(c1C(CCN1CCOCC1)c1ccc(N(C)C)cc1)OC(=O)CC2c1ccc(N(C)C)cc1 CHEMBL1446105 Potency 125.9 nM
Cn1c(CN2CCOCC2)nc2cc(NC(=O)c3ccc(F)cc3)ccc21 CHEMBL1427849 Potency 125.9 nM
O=C(Nc1cccc(Cl)c1)N1CCCC1 CHEMBL1327327 Potency 125.9 nM
C=CCSc1nc2nncc-2c(O)[nH]1 CHEMBL1351174 Potency 125.9 nM
Cc1cccc(NC(=O)CSc2[nH]cnc3ncnc2-3)c1C CHEMBL1327403 Potency 125.9 nM
CCn1c(CSc2nc3ccccc3s2)nnc1SCC(=O)c1ccc(O)c(O)c1 CHEMBL1526624 Potency 125.9 nM
S=C(NCCSCc1c(Cl)cccc1Cl)Nc1ccccc1 CHEMBL1406457 Potency 125.9 nM
O=C(NNC(=O)C12CC3CC(CC(C3)C1)C2)c1ccccn1 CHEMBL1421427 Potency 141.3 nM
COc1ccc(Nc2nc(-c3ccccc3)cs2)cc1 CHEMBL1372204 Potency 141.3 nM
COc1ccc(N2C(=O)c3ccccc3NC2(C)C)cc1 CHEMBL1578017 Potency 141.3 nM
O=C(CN1CCOCC1)N1CCN(c2ccc3ccccc3n2)CC1 CHEMBL1479502 Potency 141.3 nM
Cc1ccc(C(=O)Nc2nc(-c3cccnc3)cs2)o1 CHEMBL1578278 Potency 141.3 nM
O=C(CSc1nc2cc(Cl)ccc2[nH]1)NCCc1ccc(Cl)cc1 CHEMBL1570195 Potency 141.3 nM
CCCCCNC(=O)c1ccc2c(=O)[nH]c3c(C(=O)NCC4CCCO4)sc(=S)n3c2c1 CHEMBL1501475 Potency 141.3 nM
CCOC(=O)c1cccc(NC(=O)CSc2nnc(COc3ccccc3)n2CC)c1 CHEMBL1594586 Potency 141.3 nM
NC(=O)Nn1c(CCC(=O)O)ccc1-c1ccc(Br)cc1 CHEMBL1419908 Potency 141.3 nM
COc1ccc2cc(C(=O)C3CCCN(C(=O)CCc4cnn(C)c4)C3)ccc2c1 CHEMBL1517146 Potency 141.3 nM
Cc1csc(NC(=O)c2cc(C)oc2C)n1 CHEMBL1334993 Potency 141.3 nM
CCOC(=O)c1c(CSc2ccccc2)oc2cc(Br)c(O)c(CN(C)C)c12 CHEMBL1541153 Potency 141.3 nM
CCc1c(C#N)c(SCCC(=O)Nc2ccc(F)cc2)nc2c1C(=O)CC(C)(C)C2 CHEMBL1605450 Potency 141.3 nM
O=C(/C=C/c1ccccc1F)c1ccoc1 CHEMBL1410466 Potency 141.3 nM
CSCCO/C(O)=C1/Sc2cc(C)ccc2N=C1C CHEMBL1424399 Potency 141.3 nM
Cc1ccc(SCc2nc(-c3ccccn3)no2)cc1 CHEMBL1528371 Potency 141.3 nM
Cc1cccc(N2CCN(C(=O)c3ccccc3NC(=O)C3CCCCC3C(=O)O)CC2)c1 CHEMBL1341271 Potency 141.3 nM
COc1cc(Br)c(S(=O)(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1OC CHEMBL1371524 Potency 141.3 nM
Cc1cc(C)n(CC(=O)Nc2cccc(C(F)(F)F)c2)n1 CHEMBL1360422 Potency 141.3 nM
CNC(=O)COc1ccc(S(=O)(=O)Nc2ccccc2)cc1 CHEMBL1529066 Potency 141.3 nM
CS(=O)(=O)N1CCN(C2CCN(Cc3ccccc3)CC2)CC1 CHEMBL1525657 Potency 141.3 nM
COc1ccc(OCCCON2C(=O)c3ccccc3C2=O)cc1 CHEMBL1503734 Potency 141.3 nM
O=C(NCc1ccc(OC(F)(F)F)cc1)C1CC(c2ccccc2C(F)(F)F)=NO1 CHEMBL1425322 Potency 141.3 nM
C[C@@H]1CC=C[C@H]2[C@H]1C(=O)N(Cc1ccccc1)[C@H]2c1ccc(F)c(Br)c1 CHEMBL1393351 Potency 141.3 nM
Cc1ccc(-c2nc(N)n(C(=O)c3cccs3)n2)cc1 CHEMBL1471952 Potency 141.3 nM
Cc1ccc(CSc2nnc(-c3cccnc3)o2)cc1 CHEMBL1433297 Potency 141.3 nM
COc1ccc(-c2ccc(=O)n(CC(=O)Nc3ccc4c(c3)OCCO4)n2)cc1 CHEMBL1533653 Potency 141.3 nM
COc1cc2cc(CN(Cc3cccs3)C(S)=Nc3cccc(C)c3)c(O)nc2cc1OC CHEMBL1364347 Potency 141.3 nM
O=C(COc1ccc(S(=O)(=O)NC2CCCCC2)cc1)NCC1CCCO1 CHEMBL1560762 Potency 141.3 nM
COc1ccc(C(=O)C2CCCN(Cc3cccc4c3OCO4)C2)cc1OC CHEMBL1482679 Potency 141.3 nM
C=C(C)CN(CC)C(=O)CCc1nnc(CCc2c[nH]c3ccccc23)o1 CHEMBL1443301 Potency 141.3 nM
Oc1[nH]nc(C(F)(F)F)c1/C=N/c1ccc(Cl)cc1 CHEMBL3190650 Potency 141.3 nM
CCCCN1C(=O)C(NC(=O)CC(C)C)(C(F)(F)F)C2=C1CC(C)(C)CC2=O CHEMBL1505201 Potency 141.3 nM
Nc1cccc(C(=O)O)c1 CHEMBL307782 Potency 141.3 nM
Cc1ccc(-c2csc3nc(C)n(N)c(=O)c23)o1 CHEMBL1348714 Potency 141.3 nM
CN(c1ccc(C(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1)S(=O)(=O)c1ccccc1 CHEMBL1372654 Potency 141.3 nM
CC(C)(C)[C@@H]1C=C(C(=O)NCc2ccccc2)O[C@H](OCc2ccc(CO)cc2)C1 CHEMBL1607723 Potency 141.3 nM
CNC(=O)C[S+]([O-])CC(=O)Nc1cc(OCCOC)c(Cl)cc1Cl CHEMBL1524434 Potency 141.3 nM
Cc1ccc(CN=C(Nc2ccccc2)NC2CCCCC2)cc1 CHEMBL1587856 Potency 141.3 nM
COc1cc(CNCCO)ccc1OC1CCCC1 CHEMBL1607164 Potency 158.5 nM
CCN(CC)C(=O)C(=O)c1cccn1-c1cccc(OC)c1C#N CHEMBL1382015 Potency 158.5 nM
Cc1c(-c2ccc(Cl)cc2)[n+]([O-])c(-c2ccccc2)c[n+]1[O-] CHEMBL1490486 Potency 158.5 nM
CCc1ccc2nc(N=C(N)NC(=O)c3ccccc3)nc(C)c2c1 CHEMBL1490548 Potency 158.5 nM
O=C(c1ccc(Cl)cc1)C1CCCN(Cc2cnn(-c3ccccc3)c2)C1 CHEMBL1421724 Potency 158.5 nM
CCc1ccccc1N(C)S(=O)(=O)c1ccc2ncc(C(=O)O)c(O)c2c1 CHEMBL1557985 Potency 158.5 nM
Cc1c(C(=O)O)oc2ccc(S(=O)(=O)NCc3ccc4c(c3)OCO4)cc12 CHEMBL1342714 Potency 158.5 nM
Cc1cc(-c2cc(C(=O)NCc3ccccc3)on2)nc(NCC2CC2)n1 CHEMBL1608122 Potency 158.5 nM
CC(=O)Nc1ccc(C(=O)CSc2nc3cc(C)ccc3[nH]2)cc1 CHEMBL1303094 Potency 158.5 nM
CC(=O)Nc1ccc(NC(=O)CCc2nc(O)c3ccccc3n2)cc1 CHEMBL1333710 Potency 158.5 nM
CC(=O)c1c(C)[nH]c(C(=O)CSc2nc3cc(C)ccc3[nH]2)c1C CHEMBL1497095 Potency 158.5 nM
COCCNC(=O)c1c(CSc2ccccc2)noc1C(=O)NCc1ccccc1 CHEMBL1299551 Potency 158.5 nM
COC(=O)c1c(N=C(S)NN2CCOCC2)sc2c1CCCC2 CHEMBL1448221 Potency 158.5 nM
CCCCCCNS(=O)(=O)c1ccccc1Br CHEMBL1448333 Potency 158.5 nM
Cc1ccc(OCc2nnc(NC(=O)c3ccco3)s2)cc1 CHEMBL1492053 Potency 158.5 nM
CC/C(C)=C1\SC(N2CCOCC2)=NC1=O CHEMBL1413895 Potency 158.5 nM
Cn1ccnc1SCC(=O)c1cccc(Br)c1 CHEMBL1303718 Potency 158.5 nM
COc1ccc(CCN2CC34C=CC(O3)C(C(=O)NCc3ccccc3Cl)C4C2=O)cc1OC CHEMBL1531564 Potency 158.5 nM
O=C(Nc1ccc(C(=O)N2CCCC2)cc1)c1ccc2c(c1)OCO2 CHEMBL1449229 Potency 158.5 nM
COc1cc(OC)cc(C(=O)NCCOc2ccccc2)c1 CHEMBL1570790 Potency 158.5 nM
Cc1c(C(=O)N2CCCCCC2)oc2ccccc12 CHEMBL1531948 Potency 158.5 nM
C#CCOC(=O)C(NC(=O)c1ccccc1)=C1CCCCC1 CHEMBL1605659 Potency 158.5 nM
Cc1c(C#N)c(/N=C/N(C)C)c(C(=O)c2ccc(Br)cc2)n1-c1ccccc1 CHEMBL3209526 Potency 158.5 nM
CCOC(=O)Nc1cc(OCC)c(NC(=O)C2CC2)cc1OCC CHEMBL1566097 Potency 158.5 nM
COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CCN1CCCC(C)C1)c1ccc(N(C)C)cc1 CHEMBL1409576 Potency 158.5 nM
CC1(OC(=O)C2CCCC2)C(=O)C=C2C=C(c3ccsc3)N(CCN3CCOCC3)C=C2C1=O CHEMBL1399283 Potency 158.5 nM
CCOC(=O)c1ccccc1NC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 CHEMBL1556061 Potency 158.5 nM
COc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)N3CCCCCC3)cc2)cc1 CHEMBL1498032 Potency 158.5 nM
CCOC(=O)C1CCCCN1Cc1cc(Cl)ccc1O CHEMBL1527667 Potency 158.5 nM
CC1CNC2=C(C(=O)Nc3ccccc3)C(=O)CC(c3ccccc3)N21 CHEMBL1576143 Potency 158.5 nM
Cc1cc2cc(CCNC(=O)c3c(-c4ccccc4Cl)noc3C)c(O)nc2cc1C CHEMBL1441444 Potency 158.5 nM
CCCc1nnc(NC(=O)OCC)s1 CHEMBL1423950 Potency 158.5 nM
COc1ccc(-c2ncnc(C(F)(F)F)c2-c2csc(C)n2)c(O)c1 CHEMBL1463011 Potency 158.5 nM
COc1ccc(/C=C(\C#N)C(=O)OCC(=O)NCc2ccccc2Cl)cc1 CHEMBL1380374 Potency 158.5 nM
Cc1ccc(C(=O)Nc2nc(-c3cc(Cl)sc3Cl)cs2)cc1 CHEMBL567959 Potency 158.5 nM
Cc1ccc2nc3c(cc2c1)c(NC(=O)c1ccco1)nn3CC(C)C CHEMBL1463368 Potency 158.5 nM
CCN(CC)C(=O)c1sc2c(c1C)c(=O)n(-c1ccc(C)c(C)c1)c(=O)n2CC(=O)NCC1CCCO1 CHEMBL1502837 Potency 158.5 nM
O=C(CCC(=O)Nc1nnc(C2CCCCC2)s1)NCc1ccccc1 CHEMBL1571612 Potency 158.5 nM
Cc1ccc(-c2cc(C(=O)Nc3ccc4c(c3)OCCO4)c3ccccc3n2)cc1 CHEMBL1499276 Potency 158.5 nM
CCN(CC)C(=O)CN1C(=O)C2(NC(=O)c3ccccc3N2)c2ccccc21 CHEMBL1421324 Potency 158.5 nM
Cc1ccccc1CC1(CO)CCCN(Cc2ccc3c(c2)OCCO3)C1 CHEMBL1392149 Potency 158.5 nM
C[C@H]1[C@H](C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@H]12 CHEMBL169 Potency 158.5 nM
COc1ccc(N/C=C/C(=C(C#N)C#N)N(C)C)cc1 CHEMBL1470938 Potency 158.5 nM
COc1ccc(C2Nc3ccccc3C(=O)N2Cc2ccco2)cc1COc1ccccc1F CHEMBL1525600 Potency 158.5 nM
C=CCNC(=O)COC(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCCCC1 CHEMBL1328245 Potency 158.5 nM
CCOC(=O)/C=c1\sc2n(c1=O)CCN=2 CHEMBL3198293 Potency 158.5 nM
Cc1cccc(NC(S)=NCCN2CCOCC2)c1 CHEMBL1588790 Potency 158.5 nM
CS(=O)(=O)Nc1ccc(C(=O)N2CCN(c3ccccc3)CC2)cc1 CHEMBL1305433 Potency 158.5 nM
CCCS(=O)(=O)C(=C(Nc1ccc(OC)cc1)Nc1ccc(OC)cc1)S(=O)(=O)CCC CHEMBL1323650 Potency 158.5 nM
O=C(c1csc2c1CCCC2)N1CCN(c2ccccc2)CC1 CHEMBL1464365 Potency 158.5 nM
Cc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1S(=O)(=O)N1CCCC1 CHEMBL1464538 Potency 158.5 nM
COc1ccc(/C=N/Nc2nc(-c3ccc(C)cc3)c(NC(C)=O)s2)cc1OC CHEMBL3212636 Potency 158.5 nM
CC1(C)NC(=O)N(CC(O)COc2ccccc2C(=O)Nc2ccccc2)C1=O CHEMBL1609287 Potency 158.5 nM
C[C@@H]1CC=C[C@H]2[C@H]1C(=O)N(Cc1ccccc1)[C@H]2c1ccc(-c2ccoc2)cc1F CHEMBL1408586 Potency 158.5 nM
Cc1ccc(NC(=O)c2ccc(CNS(=O)(=O)c3cccc(C(F)(F)F)c3)cc2)cc1 CHEMBL1482102 Potency 158.5 nM
CCOC(=O)c1sc2nc(C)c([N+](=O)[O-])c(COC)c2c1N CHEMBL1494724 Potency 158.5 nM
Cc1cc(C)cc(N2CC(C(=O)O)CC2=O)c1 CHEMBL1450580 Potency 158.5 nM
N#C/C(C(N)=O)=C1/SC=C(c2ccccc2)N1c1ccccc1 CHEMBL1544430 Potency 158.5 nM
COc1ccccc1CNC(=O)c1cnn2c(C(F)F)cc(C)nc12 CHEMBL1307507 Potency 158.5 nM
CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1c1ccc(OC)cc1 CHEMBL1365523 Potency 158.5 nM
CN(C)/C=C1\NC(=S)N(c2ccccc2)C1=O CHEMBL1506100 Potency 158.5 nM
Cc1ccc(O)c(-c2cc(C(=O)Nc3ccc(S(=O)(=O)N4CC(C)OC(C)C4)cc3)n[nH]2)c1 CHEMBL1451023 Potency 158.5 nM
COC(=O)CSc1nc2ccc(NC(C)=O)cc2s1 CHEMBL1612548 Potency 158.5 nM
O=C(N/N=C/c1ccc(Cl)s1)c1ccccc1[N+](=O)[O-] CHEMBL3197979 Potency 158.5 nM
CC(C)c1nc(CNC(=O)CC2C(=O)NCCN2Cc2ccoc2)cs1 CHEMBL1326108 Potency 158.5 nM
CCOC(=O)c1ccc(NS(C)(=O)=O)cc1 CHEMBL1529997 Potency 158.5 nM
Cc1nn(-c2ncc(C(F)(F)F)cc2Cl)c(=O)n1-c1cccc(Cl)c1 CHEMBL1366109 Potency 158.5 nM
COc1ccc(NC(=O)COC(=O)c2cc(SC)ccc2Cl)c(OC)c1 CHEMBL1467702 Potency 158.5 nM
COc1ccc(-c2ccc(OC)c([C@H]3[C@H]4C=CC[C@@H](C)[C@@H]4C(=O)N3Cc3ccccc3)c2)cc1 CHEMBL1496657 Potency 158.5 nM
CCC(c1nnnn1CS(=O)(=O)c1ccc(C)cc1)N1CCN(c2nc3ccccc3s2)CC1 CHEMBL1406067 Potency 158.5 nM
CC(C)NC(=O)NC(=O)COC(=O)c1ccccc1Oc1ccccc1 CHEMBL1429131 Potency 158.5 nM
CC(=O)Nc1ccc(SC[C@H](Cc2ccccc2)N2CCN(CCc3ccccc3)CCC2=O)cc1 CHEMBL1351364 Potency 158.5 nM
O=C(NCc1ccc2c(c1)OCO2)C1CCCN(S(=O)(=O)c2cccc3nonc23)C1 CHEMBL1491678 Potency 158.5 nM
CC(C)C[C@H](NC(=O)c1[nH]cnc1C(=O)N[C@@H](C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C CHEMBL1327596 Potency 158.5 nM
COc1ccc(OCCC(=O)OCC(=O)NC(=O)NC(C)(C)C)cc1 CHEMBL1587246 Potency 158.5 nM
O=C(N=Nc1c(O)[nH]c2ccc(F)cc12)C1COc2ccccc2O1 CHEMBL1564119 Potency 158.5 nM
O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O CHEMBL275938 Potency 158.5 nM
Oc1ccc([C@@H]2CNCCc3c2cc(O)c(O)c3Cl)cc1 CHEMBL1161520 Potency 158.5 nM
Cc1cc(/C=C2\SC(Nc3ccc(F)cc3)=NC2=O)c(C)n1-c1ccc(S(N)(=O)=O)cc1 CHEMBL1460461 Potency 177.8 nM
N=C(N)NOCCC(N)C(=O)O CHEMBL182461 Potency 177.8 nM
CS(=O)(=O)C1=NSC2=NC(=O)/C(=C\c3ccc(-c4ccccc4)o3)C(=N)N21 CHEMBL1421528 Potency 177.8 nM
CCOC(=O)c1cnc2c(C(F)(F)F)cccc2c1N1CCOCC1 CHEMBL1361177 Potency 177.8 nM
C[C@@H]1C(=O)O[C@H]2[C@H]1CC[C@@]1(C)C(=O)C=C[C@@](C)(O)[C@H]21 CHEMBL1422618 Potency 177.8 nM
CCOc1nc(Nc2ccc(OC)c(Cl)c2)nc(N2CCN(c3ccc(OC)cc3)CC2)n1 CHEMBL1359064 Potency 177.8 nM
CCOC(=O)c1nn(-c2ccccc2)c2nc(-c3ccc(OC)cc3)c(C#N)c(=O)n12 CHEMBL1516670 Potency 177.8 nM
CC(C)(C)CN1CCNC(=O)C1CC(=O)NC1Cc2ccccc2C1 CHEMBL1461684 Potency 177.8 nM
Cc1cc(S(=O)(=O)NCCN(C)C)c(C)s1 CHEMBL1423078 Potency 177.8 nM
NC(=O)NCc1cccnc1 CHEMBL1380001 Potency 177.8 nM
Cc1cc(C)n2nc(CCc3nc4nc(C)cc(C)n4n3)nc2n1 CHEMBL1488428 Potency 177.8 nM
O=C(NC(=S)N1CCN(c2nc(-c3ccccc3)cs2)CC1)c1cccnc1 CHEMBL1576333 Potency 177.8 nM
COCCCN1C(=O)CS/C1=N\S(=O)(=O)c1ccccc1 CHEMBL3195810 Potency 177.8 nM
Cc1ccccc1NC(=O)CCn1c(=O)oc2ccccc21 CHEMBL1580632 Potency 177.8 nM
COC(=O)c1cc(=O)n(Cc2cccs2)/c(=N/c2ccc(F)cc2)s1 CHEMBL1998651 Potency 177.8 nM
COC(=O)C(Cc1cnc(Cl)s1)(C(=O)OC)c1ccc([N+](=O)[O-])cc1 CHEMBL1577037 Potency 177.8 nM
COc1ccccc1N1CCN(C(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)CC1 CHEMBL1604290 Potency 177.8 nM
CN(C)S(=O)(=O)c1ccc(C(=O)Nc2nnc(SCc3cccc4ccccc34)s2)cc1 CHEMBL1450571 Potency 177.8 nM
O=C(CCc1c[nH]c2ccccc12)NC1CC1 CHEMBL1312831 Potency 177.8 nM
CCOC(=O)N1CCN(C(=O)N2CCOCC2)CC1 CHEMBL1408165 Potency 177.8 nM
O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccc(Cc2ccccc2)cc1)c1ccc(Br)s1 CHEMBL1353481 Potency 177.8 nM
COc1ccc(OC)c(NC(=O)C2CC(=O)N(c3ccc(Br)cc3)C2)c1 CHEMBL1560414 Potency 177.8 nM
COc1ccc(OC)c(NC(=O)c2ccc(OC3CSC3)cc2)c1 CHEMBL1534619 Potency 177.8 nM
CCN(CC)S(=O)(=O)c1ccc(C(=O)NCC(c2cccs2)N2CCOCC2)cc1 CHEMBL1522763 Potency 177.8 nM
COC(=O)c1ccc[n+](CC(=O)c2ccc(Br)cc2)c1 CHEMBL1546270 Potency 177.8 nM
Cc1nn(-c2ccc(C(=O)OC(C)C)cc2)c(C)c1[N+](=O)[O-] CHEMBL1536162 Potency 177.8 nM
O=[N+]([O-])c1ccc(C2Oc3ccccc3C3CC(c4ccccc4)=NN32)s1 CHEMBL1326813 Potency 177.8 nM
CN(C)/C=C(/C#N)C(=O)c1cccc(Oc2ccc(C(C)(C)C)cc2)c1 CHEMBL1390621 Potency 177.8 nM
CCOC(=O)C1SC2(C(F)(F)F)CC1(O)c1c(C)cc(C)nc1O2 CHEMBL1460558 Potency 199.5 nM
Cc1nnc(SCC(=O)NCc2ccc3c(c2)OCO3)n1C CHEMBL1302143 Potency 199.5 nM
O=C(NC(=O)N1CCCc2ccccc21)c1ccccc1 CHEMBL1302737 Potency 199.5 nM
O=C(CC1OC(=O)c2ccccc21)NC1CCCCC1 CHEMBL1479937 Potency 199.5 nM
COc1ccc(OCC(=O)Nc2cccc3ncccc23)cc1 CHEMBL1565398 Potency 199.5 nM
Cc1ccc(-n2cnc(N)c2C(=O)c2cccc([N+](=O)[O-])c2)cc1 CHEMBL1536311 Potency 199.5 nM
CCNc1oc(COc2ccccc2F)nc1C#N CHEMBL1525878 Potency 199.5 nM
CN1CCc2c(OCc3ccc(F)cc3)cccc2C1=O CHEMBL1343466 Potency 199.5 nM
CCCCCn1c(CN2CCCCC2CC)nc2c1c(=O)n(C)c(=O)n2C CHEMBL1581028 Potency 199.5 nM
COc1cc(C(=O)Nc2oc(-c3ccccc3)c(-c3ccccc3)c2C#N)cc(OC)c1OC CHEMBL1606247 Potency 199.5 nM
CCOc1c(CNCCNC(=O)c2nonc2N)cccc1OC CHEMBL1460220 Potency 199.5 nM
CCn1cc(S(=O)(=O)CC(=O)Nc2ccc(C)cc2)c2ccccc21 CHEMBL1312532 Potency 199.5 nM
COc1cc(C(CC(=O)N2CCCC2)c2c(OC)cc(OC)c3c(-c4ccccc4)cc(=O)oc23)cc(OC)c1OC CHEMBL1398194 Potency 199.5 nM
Cn1c(NC(=O)c2ccccc2C(F)(F)F)cc(=O)n(C)c1=O CHEMBL1353867 Potency 199.5 nM
COCCN(C(=O)CSc1nnc(-c2ccccc2F)n1C)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O CHEMBL1526201 Potency 199.5 nM
COc1ccccc1C(OC(=O)c1cccs1)C(=O)NCC1CCCO1 CHEMBL1522517 Potency 199.5 nM
CCOC(=O)C=C1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 CHEMBL1612797 Potency 199.5 nM
O=C(N/N=C/c1cc(O)ccc1[N+](=O)[O-])c1ccc2c(c1)OCCO2 CHEMBL3194662 Potency 199.5 nM
Cc1cccc(Nc2nc(N)nc(CSc3nccc(C)n3)n2)c1 CHEMBL1367079 Potency 199.5 nM
CC(=O)Nc1ccc(OCC(O)CN2CCCCC2C)cc1 CHEMBL1469970 Potency 199.5 nM
COc1cccc2sc(NNC(=O)c3nc4ccccc4s3)nc12 CHEMBL1431314 Potency 199.5 nM
O=[N+]([O-])c1ccc(/C=N/n2c(CO)nc3ccccc32)s1 CHEMBL2001712 Potency 223.9 nM
[O-]/[N+](=C/c1ccc(F)cc1)c1ccccc1 CHEMBL1379324 Potency 223.9 nM
Cc1ccc(-n2c(Cc3cccn3C)nnc2SCC(=O)N2CCc3ccccc32)cc1 CHEMBL1303309 Potency 223.9 nM
COc1ccc(/C=C(/C#N)c2cccnc2)cc1OC CHEMBL1423437 Potency 223.9 nM
CCn1c(SCC(=O)NCCc2ccccc2)nnc1C(C)C CHEMBL1419780 Potency 223.9 nM
Fc1ccc(-c2cn3cc(C(F)(F)F)cc(Cl)c3n2)cc1 CHEMBL1462462 Potency 223.9 nM
CC1CC(C)CN(C(=O)CNS(=O)(=O)c2ccc(Br)s2)C1 CHEMBL1542467 Potency 223.9 nM
CC(C)OC(=O)CSc1nc2cc(Cl)c[nH]c-2n1 CHEMBL1345784 Potency 223.9 nM
O=C1c2oc3ccccc3c(=O)c2C(c2ccccn2)N1Cc1ccccc1 CHEMBL1506920 Potency 223.9 nM
COc1ccc(C(=O)N2CCCC2=O)cc1 CHEMBL36994 Potency 223.9 nM
CC(Sc1ccccc1)C(=O)N(CCC#N)Cc1cccnc1 CHEMBL1549076 Potency 223.9 nM
N=C(N)c1ccccc1 CHEMBL1528282 Potency 223.9 nM
CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc2ccccc21)C(C)C CHEMBL1240 Potency 251.2 nM
COc1ccc(-n2c(S)nnc2-c2cnccn2)cc1 CHEMBL1370045 Potency 251.2 nM
COc1ccc(C(=O)/C=C/c2ccc(OC)c(CN3CCOCC3)c2)cc1 CHEMBL1463767 Potency 251.2 nM
O=c1cccc2n1CC1CC2CN(Cc2cccc(Cl)c2Cl)C1 CHEMBL1352896 Potency 251.2 nM
O=C1OCc2cc(-n3cccc3)ccc21 CHEMBL1522106 Potency 251.2 nM
Cc1ccc(C(C)n2cc(C(=O)NCc3ccncc3)nn2)cc1 CHEMBL1465373 Potency 251.2 nM
CC(C)C(=O)Nc1ccc(N2CCCC2)c(Cl)c1 CHEMBL1332534 Potency 251.2 nM
CCOc1ccc(-n2cc(C(=O)c3cc(Cl)ccc3O)cc(C#N)c2=O)cc1 CHEMBL1406158 Potency 251.2 nM
Cc1ccc2nc(-c3ccncc3)cc(-c3ccccc3)c2c1 CHEMBL1411860 Potency 281.8 nM
Cn1c(CNc2ccccn2)c(C#N)c2ccccc21 CHEMBL1400644 Potency 281.8 nM
O=C(OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(=O)c2c(O)c(O)cc(C3Oc4cc(O)cc(O)c4CC3OC(=O)c3cc(O)c(O)c(O)c3)c2c1)c1cc(O)c(O)c(O)c1 CHEMBL1451483 Potency 281.8 nM
Cc1cc(NC(=O)Nc2ccc3c(ccn3C)c2)sn1 CHEMBL323356 Potency 281.8 nM
CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)CN1CCN(C/C=C/c2ccccc2)CC1 CHEMBL1556134 Potency 281.8 nM
O=C(Nc1cc(C(F)(F)F)ccc1Cl)C(Sc1nnc(O)nc1O)c1ccccc1 CHEMBL1420000 Potency 281.8 nM
CCCCOc1ccc(-n2nc(C)cc2C)nn1 CHEMBL1458970 Potency 281.8 nM
CCn1cc(C2=NC(CCSC)CO2)c2ccccc21 CHEMBL1431779 Potency 281.8 nM
O=C(c1ccc([N+](=O)[O-])cc1)N1CCSC1c1cccc(Cl)c1 CHEMBL1486285 Potency 281.8 nM
CC(/C=C1\SC(=O)N(CC(=O)Nc2cccc(O)c2)C1=O)=C\c1ccccc1 CHEMBL1313030 Potency 281.8 nM
Cc1cccc(N(Cc2ccccc2F)S(C)(=O)=O)c1 CHEMBL1481580 Potency 281.8 nM
O=C(CN1CCN(c2ncccn2)CC1)NCCC1=CCCCC1 CHEMBL1533852 Potency 281.8 nM
Cc1cc(C)cc(NC(=O)COC(=O)CCCC2=NS(=O)(=O)c3ccccc3N2)c1 CHEMBL1495606 Potency 281.8 nM
COc1cccc(/C=N/NC(=O)C(=O)N/N=C/c2cccc(OC)c2O)c1O CHEMBL3199110 Potency 281.8 nM
O=C(NCCN1CCN(Cc2ccccc2)CC1)C1c2ccccc2C(=O)N2CCc3ccccc3C12 CHEMBL1613481 Potency 281.8 nM
Cc1nc([N+](=O)[O-])c(C(=O)OCc2cccc(Br)c2)n1C CHEMBL1366599 Potency 281.8 nM
CN(CC(=O)N1CCOCC1)C(=O)CSc1nc2ccccc2s1 CHEMBL1310971 Potency 281.8 nM
Nc1c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc2n1/N=C/c1ccco1 CHEMBL3199720 Potency 281.8 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)c1ccc(O)c(O)c1 CHEMBL56393 Potency 281.8 nM
CNCc1ccccc1Sc1cc(O)ccc1O CHEMBL1359359 Potency 316.2 nM
COc1ccc(Br)cc1C1NC(=O)NC(C)=C1C(=O)N(C)C CHEMBL1419871 Potency 316.2 nM
NC(=O)c1c(N)sc2c1CCC2 CHEMBL1334647 Potency 316.2 nM
CCN(CC)S(=O)(=O)c1cccc(-c2nnc(S)n2/N=C/c2ccc(Br)cc2)c1 CHEMBL3190777 Potency 316.2 nM
C=CC[C@@H]1CC=C[C@@H](C)N1C(=O)c1cc(COc2c(F)cccc2F)on1 CHEMBL1544323 Potency 316.2 nM
CC(=O)Nc1ccc(C(=O)OCC(=O)NC(=O)NC(C)(C)C)cc1 CHEMBL1337514 Potency 316.2 nM
Cc1cc(/C=C2\SC(=S)NC2=O)c(C)n1C CHEMBL1427330 Potency 316.2 nM
CC1=Nc2cc(C(=O)O)ccc2Sc2ccc(Br)cc21 CHEMBL1562801 Potency 316.2 nM
Cc1ccc(-c2nnc(SCC(=O)NCC3CCCO3)n2C)cc1 CHEMBL1446521 Potency 316.2 nM
Cc1csc(N/N=C/c2ccc(O)c([N+](=O)[O-])c2)n1 CHEMBL3193997 Potency 316.2 nM
O=C(CSc1ccc(Cl)cc1)N1CCN(c2c(Cl)cccc2[N+](=O)[O-])CC1 CHEMBL1581193 Potency 316.2 nM
Cc1ccc(N2C(=O)c3ccccc3C2C(=O)c2ccc(O)cc2O)cc1 CHEMBL1348074 Potency 316.2 nM
NC(=O)CC1SC(N)=NC1=O CHEMBL1539845 Potency 354.8 nM
COc1ccccc1N=C(S)NNC(=O)c1nn(C)c(C)c1Cl CHEMBL1448234 Potency 354.8 nM
c1ccc(Cn2ncc3ccccc32)cc1 CHEMBL1575672 Potency 354.8 nM
Cc1cccc(N2C(=O)CCC2=O)n1 CHEMBL1402401 Potency 354.8 nM
O=C(Nc1ccccc1)C(Cc1cccs1)c1nn[nH]n1 CHEMBL1392888 Potency 354.8 nM
O=C(NCc1ccc2c(c1)OCO2)c1c(F)c(F)c(F)c(F)c1F CHEMBL1526013 Potency 354.8 nM
COCCNC(=O)c1cc2ncc(Br)cn2n1 CHEMBL1511769 Potency 354.8 nM
CC(=O)n1cc([C@H]2C=C(C(=O)Nc3ccccc3)O[C@@H](OCc3ccc(CO)cc3)C2)c2ccccc21 CHEMBL1306471 Potency 354.8 nM
CCOC(=O)CN(C(=O)CNC(=O)c1cccs1)C(C(=O)NC1CCCC1)c1cccnc1 CHEMBL1443988 Potency 354.8 nM
c1ccc(CN2OCC3Cn4c(nc5ccccc54)C32)cc1 CHEMBL1348185 Potency 354.8 nM
Cc1ccnc(SCC(=O)c2ccc(Br)cc2)c1C#N CHEMBL1545406 Potency 354.8 nM
CC(=O)O[C@H]1CC(C)(C)C(=C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(\C)C(=O)C[C@@]23O[C@]2(C)C[C@@H](O)CC3(C)C)[C@](C)(O)C1 CHEMBL1575074 Potency 354.8 nM
O=C(/C=C/c1ccccc1)NCCc1ccccc1 CHEMBL1305393 Potency 354.8 nM
Cc1cc(O)c2c(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6c(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c65 CHEMBL286494 Potency 354.8 nM
CCCCN=C(S)Nc1ccc2c[nH]nc2c1 CHEMBL1453076 Potency 398.1 nM
Cc1ccc(C(=O)OCC(=O)Nc2sccc2C(N)=O)cc1NC(=O)c1ccco1 CHEMBL1343805 Potency 398.1 nM
CCOC(=O)c1ccc2c(c1)N(CC#N)C(=O)C(C)(C)O2 CHEMBL1537253 Potency 398.1 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2CCCc1ccccc1 CHEMBL1441597 Potency 398.1 nM
CN1CCCCC1c1ccc(-c2cccnc2)nc1 CHEMBL1409518 Potency 398.1 nM
COc1cccc(N2CCN(Cc3nc(N)nc(N4CCCc5ccccc54)n3)CC2)c1 CHEMBL1576495 Potency 398.1 nM
CCOC(=O)C1CCN(CC(O)COc2ccc(C(C)(C)CC)cc2)CC1 CHEMBL1459173 Potency 398.1 nM
CN=C(Nc1cc(C)nn1CCC#N)c1ccccc1 CHEMBL1538062 Potency 398.1 nM
O=C1OCC2OC(O)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2-c2c(O)c(O)c3oc(=O)c4c(c(O)c(O)c5oc(=O)c2c3c54)-c2c1cc(O)c(O)c2O CHEMBL416615 Potency 398.1 nM
O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3ccsc3)N3CCC[C@@]123 CHEMBL1503980 Potency 398.1 nM
COc1ccc(C(=O)C2CCCN(C/C=C/c3ccccc3OC)C2)c(OC)c1 CHEMBL1353440 Potency 398.1 nM
COC(=O)c1ccc(CSc2nc3c(c(=O)n2-c2ccc(Br)cc2)SCC3)o1 CHEMBL1560726 Potency 398.1 nM
c1cc(-c2noc(CC3CCCCC3)n2)ccn1 CHEMBL1534353 Potency 398.1 nM
CC(Sc1nnnn1-c1ccccc1)C(=O)Nc1ccccc1-c1ccccc1 CHEMBL1455868 Potency 398.1 nM
CCOCCCN1CC(C(=O)NCCc2ccc(C)cc2)CC1=O CHEMBL1483257 Potency 398.1 nM
CNC(=O)Nc1ccccc1NC(=O)NC CHEMBL1479886 Potency 446.7 nM
CCC(C(=O)NCCC[C@H]1CN2C(=NC[C@@H]2C2CCCCC2)N1CCc1cccc(C)c1)c1ccccc1 CHEMBL1339488 Potency 446.7 nM
COc1ccc(C(C(=O)NC2CCCC2)N(C(=O)c2snc(-c3ccc(F)cc3)c2N)c2ccc(F)cc2)cc1 CHEMBL1362324 Potency 446.7 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCCCNC(=O)/C(C#N)=C/c1ccc(O)c(O)c1 CHEMBL67535 Potency 446.7 nM
COc1ccc(C(=O)NC(CO)c2nnc(SCc3ccc(Cl)c(Cl)c3)n2C)cc1 CHEMBL1399905 Potency 446.7 nM
CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1Nc1cccc(C(=O)O)c1 CHEMBL1521099 Potency 446.7 nM
CCCS(=O)(=O)N1CCCC(C(=O)NCCCN(C)Cc2ccccc2)C1 CHEMBL1393468 Potency 446.7 nM
Cc1cccc(C)c1NC(S)=NC(C)CCc1ccccc1 CHEMBL1467450 Potency 446.7 nM
COc1cc(C2C(C#N)=C(SC)N=C3CCCC(O)=C32)ccc1O CHEMBL1484380 Potency 446.7 nM
COCc1nnc(NS(=O)(=O)c2ccc(C)cc2)s1 CHEMBL1547073 Potency 446.7 nM
O=C(c1cccs1)N(Cc1ccco1)Cc1cc2ccccc2nc1O CHEMBL1430608 Potency 446.7 nM
COCCn1c(-c2cccc([N+](=O)[O-])c2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 CHEMBL1485407 Potency 446.7 nM
CN(C)C(=O)COc1ccc2cc(-c3ccccc3)c(=O)oc2c1 CHEMBL1431252 Potency 446.7 nM
CC(C)NC(=O)c1ccccc1NC(=O)Cc1ccc(Cl)cc1 CHEMBL1527074 Potency 501.2 nM
Cc1cc2cc(CCNC(=O)c3cccc([N+](=O)[O-])c3)c(O)nc2cc1C CHEMBL1460886 Potency 501.2 nM
CC(=O)NCCNc1ccc([N+](=O)[O-])cc1C#N CHEMBL1343123 Potency 501.2 nM
COc1cccc(CN(C)C(=O)c2ccc3nccnc3c2)c1 CHEMBL1343418 Potency 501.2 nM
O=C(CN1C2=NCCN2c2ccccc21)c1ccc(Br)cc1 CHEMBL1540598 Potency 501.2 nM
Cc1cc(C(=O)COC(=O)C2CCN(C(=O)c3ccc(Cl)cc3)CC2)c(C)n1CC1CCCO1 CHEMBL1504802 Potency 501.2 nM
COc1ccc(/N=C/c2nc(-c3ccccc3)oc2OC(=O)c2ccccc2)cc1 CHEMBL1986444 Potency 501.2 nM
COc1ccc(CNC(=O)CCS(=O)(=O)c2cccc3nonc23)cc1 CHEMBL1484155 Potency 501.2 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL1520590 Potency 501.2 nM
CN1C[C@@H](C(=O)N[C@@]2(C)O[C@]3(O)[C@H]4CCCN4C(=O)[C@@H](Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)C[C@@H]21 CHEMBL1402957 Potency 501.2 nM
CC1(C)C(=O)N=C2C1=C(O)C(=O)c1ccccc12 CHEMBL580421 Potency 501.2 nM
O=C(CC12CC3CC(CC(Br)(C3)C1)C2)NC1=NCCS1 CHEMBL1361370 Potency 562.3 nM
Cc1cccc(Nc2ncc3c(n2)CC(c2ccco2)CC3=O)c1 CHEMBL1334230 Potency 562.3 nM
CC1Cc2ccccc2N1C(=O)CSc1nnc(NC(=O)Cc2cccs2)s1 CHEMBL1329686 Potency 562.3 nM
O=C(c1ccccc1-c1ccccc1)N1CCCC1 CHEMBL1360179 Potency 562.3 nM
CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@H]5[C@@H](C)[C@H](C)CC[C@]5(C(=O)O)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C CHEMBL410525 Potency 562.3 nM
Cc1nsc(Nc2ccccc2)c1C#N CHEMBL1598155 Potency 562.3 nM
Cc1ccccc1NC(=O)C1CCCN1S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C CHEMBL1598360 Potency 562.3 nM
O=C(CSCc1c(Cl)cccc1Cl)Nc1cccnc1 CHEMBL1449662 Potency 562.3 nM
O=C1C=C(NNC(=O)c2ccncc2)CC(c2ccccc2)C1 CHEMBL1301348 Potency 562.3 nM
O=S(=O)(O)c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccc(S(=O)(=O)O)cc41)-c1ccc(S(=O)(=O)O)cc1-3)c1ccc(S(=O)(=O)O)cc21 CHEMBL1331939 Potency 562.3 nM
COc1cc(OC)c(C(=O)NCc2cccnc2)cc1OC CHEMBL1354086 Potency 562.3 nM
CN(C)c1cc(NC(=O)CNC(C)(C)CC(C)(C)C)c2ccccc2n1 CHEMBL1364430 Potency 562.3 nM
CC12CN3CC(C)(CN(C1)C3c1ccc(F)cc1)C2 CHEMBL1534179 Potency 562.3 nM
CNC(=S)N1N=C(c2ccc(OC)cc2)CC1c1ccc(N(C)C)cc1 CHEMBL1612230 Potency 562.3 nM
O=C(Nc1ccccc1)NC1CC2CCC(C1)N2Cc1nnnn1Cc1ccc2c(c1)OCO2 CHEMBL1573917 Potency 562.3 nM
CCOc1cccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)c1 CHEMBL1484034 Potency 562.3 nM
c1ccc(-c2ncc3c(ccc4ccccc43)n2)cc1 CHEMBL1457058 Potency 562.3 nM
Cc1csc(NC(=O)c2cc(-c3ccncc3)nc3ccccc23)n1 CHEMBL1467640 Potency 562.3 nM
Cc1nn2c(-c3ccncc3)nnc2c2ccccc12 CHEMBL1490793 Potency 562.3 nM
COc1ccc(/C=N/NC(=O)c2ccc(COc3cccc4cccnc34)cc2)cc1O CHEMBL3197583 Potency 562.3 nM
CCS(=O)(=O)N1Cc2ccccc2CC1C(=O)Nc1nc2ccc(C)cc2s1 CHEMBL1574914 Potency 562.3 nM
COc1ccc(-c2c(C)[n+]([O-])c3c([n+]2[O-])CCCC3)cc1 CHEMBL1536025 Potency 562.3 nM
O=c1[nH]n2c(-c3ccccc3)nc(O)c2c2ccccc12 CHEMBL1586198 Potency 562.3 nM
COc1ccc(/C=C/C(=O)O)cc1COc1ccccc1C CHEMBL1460667 Potency 631.0 nM
Cc1nc2cnc(N3CCOCC3)nc2n(Cc2ccc(F)cc2)c1=O CHEMBL1435886 Potency 631.0 nM
CC(C)CNC(=O)CCCc1c[nH]c2ccccc12 CHEMBL1493064 Potency 631.0 nM
C=C1C(=O)O[C@@H]2C[C@@H](C)[C@H]3C=CC(=O)[C@]3(O)C[C@@H]12 CHEMBL1541324 Potency 631.0 nM
CC(C)(C)c1ccc(-c2nnc3sc(-c4ccncc4)nn23)cc1 CHEMBL1565213 Potency 631.0 nM
CN1C(=C=Cc2cc(I)c(O)c(I)c2)C(C)(C)c2ccccc21 CHEMBL1400571 Potency 631.0 nM
Cc1ccccc1NC(=O)CC1SC(NC2CCCCC2)=NC1=O CHEMBL1531784 Potency 631.0 nM
Cc1c(NC(=O)CSc2nc3ccccc3[nH]2)c(=O)n(-c2ccccc2)n1C CHEMBL1376113 Potency 631.0 nM
Nc1ccc(CCS(N)(=O)=O)cc1 CHEMBL1306729 Potency 631.0 nM
CN(C)/C=N/c1ncc(C(=O)c2ccc3ccccc3c2)s1 CHEMBL3191409 Potency 631.0 nM
O=P(CCl)(Nc1ccccc1)C(Cl)(Cl)Cl CHEMBL1583412 Potency 631.0 nM
O=C(NC1(C(F)(F)F)NC(=O)N(Cc2cccnc2)C1=O)c1cccs1 CHEMBL1456605 Potency 631.0 nM
CN(C)c1ccc(C2Nc3ccccc3C(=O)N2NS(=O)(=O)c2ccccc2)cc1 CHEMBL1365693 Potency 631.0 nM
Nc1nc(-c2nonc2N)no1 CHEMBL1523789 Potency 631.0 nM
Cn1c(SCC(=O)Nc2ccc3nc(SCC(=O)N4CCCC4)sc3c2)nnc1-c1ccc(N)cc1 CHEMBL1349382 Potency 631.0 nM
NC(Cc1cc(O)c(O)cc1O)C(=O)O CHEMBL109037 Potency 631.0 nM
COc1cccc(NC(=O)Cn2c(=O)oc3ccccc32)c1 CHEMBL1524534 Potency 631.0 nM
NC(=O)CI CHEMBL276727 Potency 631.0 nM
COC(=O)c1ccc(NC(=O)CCS(=O)(=O)c2ccc(Br)cc2)cc1 CHEMBL1548937 Potency 631.0 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL50 Potency 631.0 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2OC1c1ccc(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL1514905 Potency 707.9 nM
N=C(Cc1ccc(Cl)cc1Cl)NOC(=O)c1ccc(Br)o1 CHEMBL1578142 Potency 707.9 nM
C=CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(S(=O)(=O)N(CC)CC)ccc21 CHEMBL1500504 Potency 707.9 nM
CCC(=O)OCC(=O)c1cc(C)n(-c2ccc(Br)cc2)c1C CHEMBL1333388 Potency 707.9 nM
COC(=O)c1sc(NC(=S)NC(=O)c2cccc(C)c2)nc1C CHEMBL1570479 Potency 707.9 nM
CCOC(=O)c1sc2ncc(C(=O)c3cc(Cl)cc(Cl)c3O)cc2c1C CHEMBL1609068 Potency 707.9 nM
CSCCC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)OCc1c(Cl)cccc1Cl CHEMBL1343972 Potency 707.9 nM
CSc1ccccc1NC(=O)CN(C)CC(=O)Nc1ccccc1N1CCOCC1 CHEMBL1609642 Potency 707.9 nM
O=c1cc(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL247484 Potency 707.9 nM
Cc1cc(C)n2nc(C(=O)Nc3nnc(C4CC4)s3)nc2n1 CHEMBL1463506 Potency 707.9 nM
Cc1ccc(-c2csc3nc(CSc4nnc(-c5ccc(Cl)cc5)n4C)nc(O)c23)cc1 CHEMBL1431569 Potency 707.9 nM
CC1=CC2=NC(=O)CC(C)(C(=O)N(CC(=O)NC(C)(C)C)C3CCCC3)N2C=C1 CHEMBL1376286 Potency 707.9 nM
Cc1nc2ncnn2c(C)c1CCC(=O)N1CC(C)CC(C)C1 CHEMBL1353447 Potency 707.9 nM
Clc1cccc(Cl)c1Cn1c(-c2cccnc2Cl)nc2ccccc21 CHEMBL1521608 Potency 707.9 nM
COC(=O)c1ccc(COC(=O)CNC(=O)CNC(=O)c2ccc(C)cc2)cc1 CHEMBL1307266 Potency 707.9 nM
CC(OC(=O)CCCCCNC1=NS(=O)(=O)c2ccccc21)C(=O)Nc1cc(Cl)cc(Cl)c1 CHEMBL1534873 Potency 707.9 nM
CC(=O)Nc1ccc(OC(F)(F)C(F)C(F)(F)F)c(NC(C)=O)c1 CHEMBL1506012 Potency 707.9 nM
Cc1ccc2c(c1)N(CC(=O)N1CCCc3ccccc31)C(=O)C(C)O2 CHEMBL1562034 Potency 707.9 nM
Oc1ccc(CNc2ccc(F)cc2)c2cccnc12 CHEMBL1506510 Potency 707.9 nM
CC(=O)c1cc(-c2ccccc2)n(CCC(=O)NCc2cccs2)c1C CHEMBL1391517 Potency 707.9 nM
O=C(c1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1)N1CCC2(CC1)OCCO2 CHEMBL1383746 Potency 707.9 nM
NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1437 Potency 707.9 nM
Cc1cc2oc(=O)cc(CN3CCN(S(=O)(=O)c4cccs4)CC3)c2cc1C CHEMBL1439715 Potency 794.3 nM
CN(CC(=O)NCCc1ccccc1)S(=O)(=O)c1c[nH]cn1 CHEMBL1373101 Potency 794.3 nM
COc1ccc(C2SCCN2C(S)=Nc2cccc(C(F)(F)F)c2)cc1 CHEMBL1569834 Potency 794.3 nM
COc1cccc(C(=O)N(c2ccc(C)cc2)C2C=CS(=O)(=O)C2)c1 CHEMBL1555439 Potency 794.3 nM
COc1cccc(NC(=O)OCCN2CCN(Cc3ccccc3)CCC2=O)c1 CHEMBL1331136 Potency 794.3 nM
CNC(=O)c1ccccc1NC(=O)c1c(O)nc2c(c1O)CCCC2 CHEMBL1462320 Potency 794.3 nM
CCN1C(=O)/C(=C/C=C2\N(CC)c3cc(S(=O)(=O)N(C)C)ccc3N2c2ccccc2)SC1=S CHEMBL1516758 Potency 794.3 nM
COC(=O)c1ccc(C(C(=O)NC2CCCCC2)N(Cc2ccccc2)C(=O)Cc2cccs2)cc1 CHEMBL1399054 Potency 794.3 nM
COc1ccc(NC2=C3CCCC=C3N(c3ccc(OC)cc3)C2=O)cc1 CHEMBL1438350 Potency 794.3 nM
N#Cc1nc(-c2ccco2)oc1N1CCN(c2cccc(Cl)c2)CC1 CHEMBL1369929 Potency 794.3 nM
Cc1cc(C(=O)O)ccc1-n1c(C)cc(/C=C(/C#N)C(=O)Nc2ccccc2)c1C CHEMBL1438738 Potency 794.3 nM
COc1cc(S(=O)(=O)N2CCOCC2)ccc1NC(=O)CSc1nnc(O)nc1O CHEMBL1322489 Potency 794.3 nM
O=C(CSc1nc2ccccc2c(=O)n1-c1ccc(F)cc1)Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1 CHEMBL1480933 Potency 794.3 nM
CC(C)(C)C(=O)NCCCc1nc2ccccc2n1CCCOc1ccc(Cl)cc1 CHEMBL1330934 Potency 794.3 nM
Cc1ccc(CNC(=O)CCNC(=O)Cn2ccc3ccccc3c2=O)o1 CHEMBL1517633 Potency 794.3 nM
O=S1(=O)C=CC(Nc2ccccc2)C1 CHEMBL1481146 Potency 794.3 nM
O=C(NCc1nc2ccccc2[nH]1)C1=C[C@H](C2CC2)C[C@H](OCCCCO)O1 CHEMBL1301233 Potency 794.3 nM
O=C(Nc1cccc(F)c1)/C(=C\c1ccco1)NC(=O)c1cccs1 CHEMBL1331780 Potency 794.3 nM
CCN1C(=O)N(C)[C@@H](c2ccccc2)C(C(=O)OC)=C1C CHEMBL1439454 Potency 794.3 nM
Brc1ccc(C2Nc3cccc4cccc(c34)N2)o1 CHEMBL1341830 Potency 794.3 nM
O=c1cc(O)cc(/C=C/c2ccc(O)c(O)c2)o1 CHEMBL1224512 Potency 794.3 nM
CCOC(=O)c1ccc(Cn2cnc3ccccc3c2=O)cc1 CHEMBL1486228 Potency 794.3 nM
C[C@H]1Cc2c(-c3ccccc3)nc3c(c2CO1)CN(C(=O)Nc1cccc(C#N)c1)CC3 CHEMBL1603460 Potency 794.3 nM
N#CCC1c2ccccc2CCN1C(=O)Nc1ccc(Cl)cc1 CHEMBL1312923 Potency 794.3 nM
O=C(NCc1ccccc1)N(Cc1cc2cc3c(cc2nc1O)OCCO3)CC1CCCO1 CHEMBL1352976 Potency 794.3 nM
CC(=O)Oc1ccccc1N1C(=O)c2ccc(C(=O)O)cc2C1=O CHEMBL1481642 Potency 794.3 nM
CN=C(S)N1CCN(C(=O)C2CCCO2)CC1 CHEMBL1571868 Potency 794.3 nM
COc1nc(-c2cnccn2)sc1C CHEMBL1393455 Potency 794.3 nM
Cc1cc(C)n(CCN(C)Cc2cn(C)nc2-c2ccccc2F)n1 CHEMBL1511724 Potency 794.3 nM
Cc1ccccc1N=C(S)N1CCN(Cc2ccccc2)CC1 CHEMBL1504151 Potency 794.3 nM
CC(C)C(=O)N1CCN(c2nc(-c3ccccc3)c3c(c2C#N)CC(C)(C)OC3)CC1 CHEMBL1364268 Potency 794.3 nM
CC(C)(C)c1ccc(C[S+]([O-])CC(O)CO)cc1 CHEMBL1306497 Potency 794.3 nM
CCOc1cc(NC(=O)c2cccc(C)c2)c(OCC)cc1N=C(S)NCC1CCCO1 CHEMBL1416703 Potency 794.3 nM
CCC(C(=O)OCC(=O)Nc1ccc(C(N)=O)cc1)c1ccccc1 CHEMBL1545437 Potency 794.3 nM
O=C(O)C(=O)/C(=C\c1ccc([N+](=O)[O-])cc1)c1ccc2ccccc2n1 CHEMBL1584363 Potency 794.3 nM
O=C(Nc1nnc(SCc2ccccc2)s1)c1cccs1 CHEMBL1390889 Potency 794.3 nM
Nc1nc2c(ncn2COCCO)c(=O)[nH]1 CHEMBL184 Potency 794.3 nM
COC(=O)CSc1nc2nc(C)cc(C)n2n1 CHEMBL1557425 Potency 891.3 nM
CCCn1c(SCC(=O)NCC2CCCO2)nc2c1c(=O)n(C)c(=O)n2C CHEMBL1332638 Potency 891.3 nM
CCOc1cc(CNc2ccc(N3CCOCC3)cc2)cc(Br)c1OCC CHEMBL1342281 Potency 891.3 nM
O=C(COC(=O)C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)NCCc1ccccc1 CHEMBL1539589 Potency 891.3 nM
Cc1c(C(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cccc1[N+](=O)[O-] CHEMBL1328501 Potency 891.3 nM
Cc1cc(C)cc(N(C(=O)c2ccc(Br)o2)C2C=CS(=O)(=O)C2)c1 CHEMBL1597171 Potency 891.3 nM
Cc1cccc(-n2c(SCC(=O)O)nc3sc4c(c3c2=O)CCC4)c1 CHEMBL1531433 Potency 891.3 nM
COc1ccc(N2CCN(C(CNC(=O)c3ccco3)c3cccnc3)CC2)cc1 CHEMBL1540698 Potency 891.3 nM
C[C@@H]1NC(=O)c2cc([N+](=O)[O-])cc(I)c2OCC[C@@H](C(=O)NC(CC(=O)O)C(N)=O)NC(=O)[C@H](CCC(=O)O)NC1=O CHEMBL1359274 Potency 891.3 nM
COc1ccc(C(=O)NC(=S)NCC2CCCO2)cc1 CHEMBL1448630 Potency 891.3 nM
COc1cccc(C2CC(c3ccc(F)cc3)Nc3nc(N)nn32)c1 CHEMBL1576191 Potency 891.3 nM
Cc1cc2c(ncn2C)c(NS(=O)(=O)c2ccc(Cl)cc2)c1C CHEMBL1453292 Potency 891.3 nM
CC1CN(C)C(C)CC1NCc1ccc2c(c1)OCO2 CHEMBL1531893 Potency 891.3 nM
Cc1cc(C)c(C#N)c(SC(F)F)n1 CHEMBL1481115 Potency 891.3 nM
Cc1ccc(N(Cc2cc3ccccc3nc2O)C(=O)c2ccco2)c(C)c1 CHEMBL1399669 Potency 891.3 nM
N#CC1=C(N)N(c2ccc(F)cc2)C2=C(C1c1ccc(O)cc1)S(=O)(=O)CC2 CHEMBL1415045 Potency 891.3 nM
CCOC(=O)C1(C(F)(F)F)N=C(c2cccnc2)OC(N2CCOCC2)=N1 CHEMBL1598380 Potency 891.3 nM
O=[N+]([O-])c1cc(C2Nc3cccc4cccc(c34)N2)ccc1Cl CHEMBL1363368 Potency 891.3 nM
COc1ccc(-n2cc3c(-c4cccc(Br)c4)nnc(C)c3n2)cc1 CHEMBL1411573 Potency 891.3 nM
C/C(CC(=O)N(C(C)C)C(C)C)=N\NC(=O)COc1ccc(Cl)cc1Cl CHEMBL3190722 Potency 891.3 nM
CCc1nn2cc(-c3ccccc3)nc2s1 CHEMBL1510399 Potency 891.3 nM
Cc1ccc(-c2ccc(CCC(=O)O)n2CC2CCCO2)cc1 CHEMBL1312956 Potency 891.3 nM
Cc1cc(Cl)ccc1N=C(S)NCCCN1CCCC1=O CHEMBL1353627 Potency 891.3 nM
COC(=O)c1ccccc1NC(=O)C1CCCCC1C(=O)O CHEMBL1443098 Potency 891.3 nM
Nc1n[nH]c(SCC(=O)Nc2ccc([N+](=O)[O-])cc2Br)n1 CHEMBL1416441 Potency 891.3 nM
Cc1noc(C)c1COc1ccc(C(=O)Nc2cccnc2)cc1 CHEMBL1455554 Potency 891.3 nM
CCOc1ccc(S(=O)(=O)N2CCN(c3ccc(OC)cc3)CC2)c2cccnc12 CHEMBL1377627 Potency 891.3 nM
CCc1c(C)nc(N)n2c(SCC(=O)Nc3ccccc3)nnc12 CHEMBL1483307 Potency 891.3 nM
CC1(C)CC(=O)C(CC(=O)N2CCC(Cc3ccccc3)CC2)C(=O)C1 CHEMBL1388128 Potency 891.3 nM
CC1CCCC(C)N1C(=O)COC(=O)c1cccnc1O CHEMBL1483557 Potency 891.3 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 Potency 891.3 nM
Cc1cc(C)[n+](-c2ccc(C(C)C)cc2)c2[nH]c(=O)[nH]c(=O)c12 CHEMBL1523023 Potency 891.3 nM
Cc1cc(=O)c(C(=O)O)cn1-c1ccc(C(C)C)cc1 CHEMBL1365799 Potency 891.3 nM
Cc1cccc(C(P(=O)(c2ccccc2)c2ccccc2)P(=O)(c2ccccc2)c2ccccc2)n1 CHEMBL1308571 Potency 891.3 nM
C1CCc2c(nc3nnnn3c2NC2CCCC2)C1 CHEMBL1405459 Potency 891.3 nM
COC(=O)c1cc(OC)c(OC)cc1NCC(=O)Nc1cccc(C(F)(F)F)c1 CHEMBL1348826 Potency 891.3 nM
Cc1ccc(-n2nnc(-c3nccs3)n2)cc1 CHEMBL1574374 Potency 891.3 nM
Nc1c(S(=O)(=O)[O-])cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccc(S(=O)(=O)[O-])cc4)n3)c(S(=O)(=O)[O-])c2)c2c1C(=O)c1ccccc1C2=O CHEMBL1365553 Potency 891.3 nM
COc1cc(/C=C(\C#N)C(=O)c2ccc(O)c(O)c2)cc(I)c1O CHEMBL1257003 Potency 891.3 nM
COc1ccc(C(=N)NO)cc1O CHEMBL1506999 Potency 891.3 nM
C/C(CCc1ccc2c(c1)OCO2)=N\NC(=O)c1ccccc1Cl CHEMBL3214629 Potency 891.3 nM
N=c1c(-c2nc3ccccc3[nH]2)cc(C(=O)c2ccco2)nn1-c1ccccc1 CHEMBL1445168 Potency 891.3 nM
CCOc1ccc(/C=N/NC(=O)COc2ccccc2-c2ccccc2)cc1 CHEMBL3193466 Potency 891.3 nM
CCOc1ccc(C(=O)C2CCN(C(=O)c3ccccc3C(=O)O)CC2)cc1 CHEMBL1406261 Potency 891.3 nM
COc1ccc(CNC(=O)c2ccc(=O)oc2)cc1OC CHEMBL1390169 Potency 891.3 nM
O=C(COC(=O)C1=COCCO1)Nc1ccccc1Oc1ccccc1 CHEMBL1547386 Potency 891.3 nM
Cc1c(N2C(=O)CS/C2=N\N=C\c2ccccc2O)c(=O)n(-c2ccccc2)n1C CHEMBL3189880 Potency 891.3 nM
NNC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1390521 Potency 891.3 nM