COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL5172767 Kd 6.1 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(Cl)c5)c4c3c2)cn1 CHEMBL5174723 Kd 7.3 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(C)c5)c4c3c2)cn1 CHEMBL5199096 Kd 8.4 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(F)c5)c4c3c2)cn1 CHEMBL5190698 Kd 18.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4cnn(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL5399070 Kd 19.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(OC)c5)c4c3c2)cn1 CHEMBL5184015 Kd 47.5 nM
COc1ccc(-c2ccc3[nH]c(=O)c4c(c3c2)n(-c2ccc(N3CCNCC3)c(C(F)(F)F)c2)c(=O)n4C)cn1 CHEMBL5417058 Kd 48.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 49.0 nM
COc1ccc(-c2ccc3c(c2)c2c(nnn2-c2ccc(N4CCNCC4)c(C(F)(F)F)c2)c(=O)n3C)cn1 CHEMBL5192566 Kd 49.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4ncc(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)n4c3c2)cn1 CHEMBL5417476 Kd 53.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4cnc(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)n4c3c2)cn1 CHEMBL5439857 Kd 56.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4ncn(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL5406944 Kd 62.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCN(C)CC6)cc5)c4c3c2)cn1 CHEMBL5190197 Kd 63.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)cc5)c4c3c2)cn1 CHEMBL5194039 Kd 63.0 nM
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL608533 Kd 97.0 nM
COc1ccc(-n2nnc3c(=O)[nH]c4ccc(-c5ccc(OC)nc5)cc4c32)cc1 CHEMBL5190993 Kd 120.0 nM
CN(C)C(=O)Cc1ccc(N2CCCN(c3ccnc4sc(C(N)=O)c(N)c34)CC2)cc1 CHEMBL2348353 Kd 130.0 nM
CN(C)c1ccc(/N=N/c2ccccn2)c(O)c1 CHEMBL4858983 IC50 130.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 140.0 nM
Cc1ccnc(NC(=O)Cc2ccc3ccccc3c2)c1 CHEMBL4781866 Kd 140.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4ccc(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)n4c3c2)cn1 CHEMBL5416400 Kd 165.0 nM
Oc1ccc2ccccc2c1/C=C/c1nccs1 CHEMBL5174394 Kd 200.0 nM
Oc1ccc2ccccc2c1/N=N/c1nccs1 CHEMBL2094383 Kd 200.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(-c6ccccc6)cc5)c4c3c2)cn1 CHEMBL5187692 Kd 235.0 nM
CN(C)C(=O)c1ccc(N2CCCN(c3ccnc4sc(C(N)=O)c(N)c34)CC2)cc1 CHEMBL2348350 Kd 240.0 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 CHEMBL572878 Kd 250.0 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 Kd 260.0 nM
CCOc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL5184335 Kd 385.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 390.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(Cl)cc5)c4c3c2)cn1 CHEMBL5189953 Kd 455.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 550.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCNCC6)cc5C(F)(F)F)c4c3c2)cn1 CHEMBL5177849 Kd 575.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 Kd 610.0 nM
C[C@@H]1COCCN1c1cc(-c2ccnn2C)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4647810 Kd 660.0 nM
CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1 CHEMBL521851 Kd 670.0 nM
Oc1cccc(-c2nc(N3CCOCC3)c3oc4ncccc4c3n2)c1 CHEMBL573339 Kd 770.0 nM
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F CHEMBL1230020 Kd 770.0 nM
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(C)cc5)c4c3c2)cn1 CHEMBL5205288 Kd 810.0 nM
O=c1[nH]c2ccc(-c3cccnc3)cc2c2c1nnn2-c1ccc(N2CCNCC2)c(C(F)(F)F)c1 CHEMBL5188981 Kd 840.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM