C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)C(=O)O)o3)nc2C(=O)N2CCCC[C@@H]2C)c(C(F)F)c1F)C(F)(F)F CHEMBL4635823 Kd 0.003 nM
COc1nc2ccc(C(O)(c3cnc(C)n3C)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3929357 Kd 0.017 nM
COc1nc2ccc(C(O)(c3cc(C)nc(C)c3)c3cnnn3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4441287 Kd 0.02 nM
COc1nc2ccc(C(O)(c3sc(C)nc3C)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3358455 Kd 0.024 nM
COc1nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3910514 Kd 0.026 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)C(=O)O)o3)nc2CC2CCCCC2)c(C(F)F)c1F)C(F)(F)F CHEMBL4642631 Kd 0.03 nM
Cc1ccc(C(O)(c2ccc3nc(C#N)c(Cc4ccc(C(F)(F)F)cc4)c(C#N)c3c2)c2cnnn2C)c(C)n1 CHEMBL3969443 Kd 0.04 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)C(=O)O)o3)nc2CC2CCCC2)c(C(F)F)c1F)C(F)(F)F CHEMBL4637144 Kd 0.04 nM
COc1nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc2c(C#N)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3978521 Kd 0.05 nM
CCC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c(Cl)c1C CHEMBL3314002 Kd 0.05 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CC34CCOCC4)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4635066 Kd 0.05 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(CC(C)(C)C(=O)O)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4647899 Kd 0.05 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CC[C@@H](F)C[C@@H]2C)c(Cl)c1Cl)C(F)(F)F CHEMBL4643698 Kd 0.06 nM
CC(C)(O)CNC(=O)c1nc(C(=O)N2CCC(F)CC2)c(-c2ccc(S(=O)(=O)N[C@@H](C(C)(C)C)C(F)(F)F)c(Cl)c2Cl)s1 CHEMBL4646424 Kd 0.07 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)C(=O)O)o3)nc2Cc2ccc(F)cc2)c(C(F)F)c1F)C(F)(F)F CHEMBL4633899 Kd 0.07 nM
CCC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128575 Kd 0.077 nM
CC(C)(O)CNC(=O)c1nc(C(=O)N2CCC(F)(F)CC2)c(-c2ccc(S(=O)(=O)NC3(C(F)(F)F)CC3)c(Cl)c2Cl)s1 CHEMBL4635866 Kd 0.078 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CC1CCC(F)(F)CC1 CHEMBL4442831 Kd 0.1 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3905654 Kd 0.1 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2c1CCCC2 CHEMBL4126366 Kd 0.11 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 Kd 0.12 nM
CCN(C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl)C12CC(C1)C2 CHEMBL4649882 Kd 0.17 nM
C[C@H]1CCCCN1C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1cnc(NCC(C)(C)C)cc1C(F)(F)F CHEMBL5279079 Kd 0.17 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12)C(F)(F)F CHEMBL4127282 Kd 0.18 nM
CC(C)(CCF)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4127189 Kd 0.22 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC3(CC2)CC3)c(Cl)c1Cl)C(F)(F)F CHEMBL4639401 Kd 0.22 nM
CC(C)[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4644895 Kd 0.22 nM
CCc1nc2ccc(C(O)(c3cnnn3C)C3CN(S(C)(=O)=O)C3)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3931712 Kd 0.23 nM
C[C@@H]1CCN(C(=O)c2c(NC(=O)c3cccnc3)sc3c2CCCC3)[C@H](C)C1 CHEMBL5433435 IC50 0.23 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCCC[C@@H]2C)c(Cl)c1Cl)C(F)(F)F CHEMBL4634571 Kd 0.25 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)c3noc(=O)[nH]3)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4636006 Kd 0.26 nM
COc1nc2ccc(C(O)(c3cnc(C)n3C)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL4216372 Kd 0.27 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(CC(C)(C)C(=O)O)nc2CC2CCC2)c(C(F)F)c1F)C(F)(F)F CHEMBL4641138 Kd 0.27 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(C#N)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3980600 Kd 0.28 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N(CC)CC)c(Cl)c1Cl)C(F)(F)F CHEMBL4639653 Kd 0.28 nM
COc1nc2c(C)cc(C(O)(c3cncn3C)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3955811 Kd 0.29 nM
COc1nc2ccc(C(O)(c3ccnc(C(F)(F)F)c3)c3cncn3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4552142 Kd 0.3 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)C(=O)O)o3)nc2CN2CCCC(F)(F)C2)c(C(F)F)c1F)C(F)(F)F CHEMBL4642674 Kd 0.3 nM
CCc1nc2ccc(C(O)(c3cnnn3C)C3CN(C(C)=O)C3)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3894779 Kd 0.32 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2nc(CC3CCCCC3)c(-c3ccc(S(=O)(=O)NC(C)(C)C)c4ccccc34)s2)cc1 CHEMBL4130294 Kd 0.33 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4636441 Kd 0.33 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CCS(=O)(=O)CC3)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4648441 Kd 0.35 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)C(=O)O)o3)nc2CC2CCC2)c2ccccc12)C(F)(F)F CHEMBL4642450 Kd 0.35 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(CC(C)(C)C(=O)O)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4647734 Kd 0.36 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)C(N)=O)nc2CC2CCCCC2)c2ccccc12 CHEMBL4127127 IC50 0.37 nM
COc1nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL4204175 Kd 0.38 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)(F)CC2)c(Cl)c1F)C(F)(F)F CHEMBL4637844 Kd 0.38 nM
CSc1ncc(Cl)c(C(=O)Nc2sc3c(c2C(=O)NCc2ccccc2)CCCC3)n1 CHEMBL5418139 IC50 0.38 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3noc(CC(C)(C)C(=O)O)n3)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4632527 Kd 0.39 nM
CCN(CC(F)(F)F)C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4640811 Kd 0.4 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c(Cl)c1Cl CHEMBL4129656 Kd 0.44 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CCOCC3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4125757 Kd 0.45 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CS(=O)(=O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128363 Kd 0.48 nM
CC1CCN(C(=O)c2nc(C(=O)NCC(C)(C)O)sc2-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c2Cl)CC1 CHEMBL4637820 Kd 0.48 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CC[C@H](F)C[C@@H]2C)c(Cl)c1Cl)C(F)(F)F CHEMBL4634281 Kd 0.48 nM
Cn1cncc1C(O)(c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1)c1ccnc2ccccc12 CHEMBL4205065 Kd 0.5 nM
COc1nc2ccc([C@](O)(c3ccnc(C(F)(F)F)c3)c3cnc(C)n3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4466272 Kd 0.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCCC[C@@H]2C)c(C(F)F)c1F)C(F)(F)F CHEMBL4648715 Kd 0.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3cnc(CC(C)(C)C(=O)O)s3)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4645288 Kd 0.5 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(N3CCC3)c(Oc3ccc(Cl)cc3)c(Cl)c2c1 CHEMBL3984833 Kd 0.53 nM
CCN(C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl)C1CCC1 CHEMBL4645338 Kd 0.53 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4645439 Kd 0.56 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2Cc2ccc(F)cc2)c(Cl)c1Cl)C(F)(F)F CHEMBL4126317 Kd 0.59 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1C)C(F)(F)F CHEMBL4642426 Kd 0.59 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cnc(O[C@@H](C)c3ccccc3)c(Cl)c2)cc1 CHEMBL4175305 IC50 0.6 nM
Cc1cc(C(O)(c2ccc3nc(Cl)c(-c4ccccc4)c(Cl)c3c2)c2cncn2C)ccn1 CHEMBL4217859 Kd 0.6 nM
COc1nc2ccc(C(O)(c3cnc(C)n3C)C3CCOCC3)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4584135 Kd 0.6 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4646118 Kd 0.6 nM
COc1nc2ccc(C(O)(c3oc(C)nc3C)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3963440 Kd 0.63 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)C#N)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4643780 Kd 0.63 nM
COc1nc2ccc(C(O)(c3cnnn3C)C3CN(C(C)=O)C3)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3912618 Kd 0.64 nM
Cc1ccnc(SCC(=O)Nc2sc3c(c2C(=O)NCc2ccccc2)CCCC3)n1 CHEMBL5424936 IC50 0.69 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(C(C)(C)O)o3)nc2C(=O)N2CCC(F)(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4649427 Kd 0.7 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(C#N)c(Cc3ccc(-n4cccn4)cc3)c(C#N)c2c1 CHEMBL3325743 Kd 0.71 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(N3CCC3)c(Oc3ccc(C#N)cc3)c(Cl)c2c1 CHEMBL3959629 Kd 0.72 nM
C[C@H]1[C@H](C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@H]12 CHEMBL169 IC50 0.75 nM
CCc1nc2ccc(C(O)(c3cnnn3C)C3CN(C(=O)OC(C)(C)C)C3)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3922753 Kd 0.77 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N3CC4(C3)CS(=O)(=O)C4)nc2CC2CCCCC2)c(Cl)c1Cl CHEMBL4129494 Kd 0.77 nM
CC(C)(O)CNC(=O)c1nc(CC2CCCCC2)c(-c2ccc(S(=O)(=O)NC3(C#N)CC3)c3ccccc23)s1 CHEMBL4128262 Kd 0.78 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)N3CC4(C3)CS(=O)(=O)C4)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4643849 Kd 0.78 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(-c3nnc(C(C)(C)O)o3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4648607 Kd 0.82 nM
CSc1ncc(Cl)c(C(=O)Nc2sc3c(c2C(=O)NC2CCS(=O)(=O)C2)CCC(C)C3)n1 CHEMBL5434019 IC50 0.82 nM
OC(c1ccncc1)(c1ccc2nc(Cl)c(Cc3ccc(Cl)cc3)c(Cl)c2c1)c1cncs1 CHEMBL3325742 Kd 0.83 nM
OC(c1cccnc1)(c1ccc2nc(Cl)c(Cc3ccc(Cl)cc3)c(Cl)c2c1)c1cncs1 CHEMBL3892267 Kd 0.83 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCCC[C@@H]2C)c(C(F)F)c1F)C(F)(F)F CHEMBL4646215 Kd 0.88 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CC(F)(F)C[C@@H]2C)c(Cl)c1Cl)C(F)(F)F CHEMBL4644553 Kd 0.9 nM
Cc1c(S(=O)(=O)NC(C)(C)C)ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c1OC(F)F CHEMBL4130056 Kd 0.92 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCC2)c2ccccc12)C(F)(F)F CHEMBL4129634 Kd 0.98 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cccc(-c3cc(Cl)ccc3Cl)c2)cc1 CHEMBL3314018 EC50 1.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)F)c(Cl)c2)cc1 CHEMBL3314017 EC50 1.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3314016 EC50 1.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3)c(C(C)C)c2)cc1 CHEMBL3314015 EC50 1.0 nM
Cc1ccc(C(NC(=O)Cc2ccc(N(CC(=O)O)Cc3c(C)noc3C)cc2)c2ccccc2)cc1 CHEMBL3314028 IC50 1.0 nM
Cc1ccc([C@@H](NC(=O)Cc2ccc3oc(C(c4ccncc4)N4CC(N)C4)cc3c2)c2ccccc2)c(C)c1 CHEMBL3314027 IC50 1.0 nM
Cc1cnc(C(CCC(C)C)NC(=O)Cc2ccc3oc(C(O)c4c(C)noc4C)cc3c2)c(C)c1 CHEMBL3314026 IC50 1.0 nM
Cc1cc(Cl)ccc1C(NC(=O)Cc1ccc(OCc2c(C)noc2C)cc1)c1ccc(Cl)cc1 CHEMBL3314025 IC50 1.0 nM
Cc1ccc(C(NC(=O)Cc2ccc(OCC(O)c3cccnc3C)cc2)c2ccccc2)c(C)c1 CHEMBL3314023 IC50 1.0 nM
O=C(O)[C@@H]1CCN(c2nn(C(=O)c3c(Cl)cccc3C3CC3)c3cccc(F)c23)C[C@H]1O CHEMBL4439154 IC50 1.0 nM
O=C(O)c1ccc(-n2cc(C(=O)c3c(Cl)cccc3Cl)c3cccc(F)c32)cc1 CHEMBL4578385 IC50 1.0 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N(CC)CC)c(C(F)F)c1Cl)C(F)(F)F CHEMBL4636470 Kd 1.0 nM
Cc1ncc(C(=O)Nc2cc(Cl)cc(CN3CCN(C(=O)C4CCCC4)[C@@H](C)C3)c2C)cn1 CHEMBL5205088 IC50 1.0 nM
CC(C)(O)CNC(=O)c1nc(CC2CCCCC2)c(-c2ccc(S(=O)(=O)NC(C)(C)C)c3ccccc23)s1 CHEMBL4129202 Kd 1.1 nM
Cc1nc(C)c(C(O)(c2ccc3nc(Cl)c(-c4ccccc4)c(Cl)c3c2)c2cncn2C)s1 CHEMBL4209944 Kd 1.1 nM
COc1nc2ccc([C@@](O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4556738 Kd 1.1 nM
O=C(O)c1ccc(-n2cc(C(=O)c3c(Cl)cccc3Cl)c3ccccc32)c(F)c1 CHEMBL4570491 IC50 1.1 nM
CCN(C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl)C(C)C CHEMBL4647081 Kd 1.1 nM
CN1CCN(CC(=O)Nc2sc3c(c2C(=O)NCc2ccccc2)CCCC3)CC1 CHEMBL5409745 IC50 1.17 nM
C[C@H](NC(=O)c1cc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)cc(C2(C)CC2)c1)C(F)(F)F CHEMBL4128042 IC50 1.2 nM
COc1nc2ccc(C(O)(c3cnc(C)n3C)c3cnc(C)n3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4575356 Kd 1.2 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCCC(C)(C)C(N)=O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4649516 Kd 1.2 nM
COc1nc2ccc(C(N)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3954988 Kd 1.3 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NC34CC(C(=O)O)(C3)C4)nc2CC2CCCCC2)c2ccccc12 CHEMBL4127765 Kd 1.3 nM
CC(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c(C(F)F)c1Cl CHEMBL4128687 Kd 1.3 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)N3CC4(C3)CS(=O)(=O)C4)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4127932 IC50 1.3 nM
CCn1c2ccccc2c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc21 CHEMBL3314031 IC50 1.3 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CC1CC1 CHEMBL4521699 Kd 1.3 nM
COc1nc2ccc(C(O)(c3ccnc(C(F)(F)F)c3)c3cnnn3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4543938 Kd 1.3 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3ccccc23)cc1 CHEMBL3598140 IC50 1.3 nM
COc1ccc(C(O)(c2ccc3nc(OC)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cncs2)cn1 CHEMBL3921394 Kd 1.4 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(N3CCC3)c(Cc3ccc(C(F)(F)F)cc3)c(Cl)c2c1 CHEMBL3900207 Kd 1.4 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1C1CCCC1 CHEMBL4444337 Kd 1.4 nM
CC[C@H]1CCCN1C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4649396 Kd 1.4 nM
O=C(N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12)C1(O)CCCCC1 CHEMBL4848024 EC50 1.4 nM
CCC1CCc2c(sc(NC(=O)c3ccnn3C)c2C(=O)Nc2ccccc2C)C1 CHEMBL5438268 IC50 1.47 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3896579 Kd 1.5 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4588531 Kd 1.5 nM
CCN(CC(C)C)C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4646438 Kd 1.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3cc(CC(C)(C)C(=O)O)ncn3)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4649210 Kd 1.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(C(C)(C)O)n3C)nc2C(=O)N2CCC(F)(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4633325 Kd 1.5 nM
Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Cc3ccc(-n4cccn4)cc3)c(C#N)c2c1 CHEMBL3961579 Kd 1.6 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N3CC(C(C)(C)C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4129163 IC50 1.6 nM
O=C(O)c1ccc(-n2cc(C(=O)c3c(Cl)cccc3Cl)c3ccccc32)cc1 CHEMBL4454027 IC50 1.6 nM
O=C(Nc1sc2c(c1C(=O)N1CCN(Cc3ccccc3)CC1)CCCC2)c1ccccc1F CHEMBL5432066 IC50 1.63 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CC(F)(F)C[C@@H]2C)c(C(F)F)c1F)C(F)(F)F CHEMBL4645069 Kd 1.7 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4636398 Kd 1.7 nM
CCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)c(CO)c2)cc1 CHEMBL4225088 IC50 1.71 nM
O=C(Nc1sc2c(c1C(=O)N[C@H]1CC[C@H](O)CC1)CCCC2)c1cccnc1 CHEMBL5403342 IC50 1.76 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCCCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4645916 Kd 1.8 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(C)(C)C2)c(Cl)c1Cl)C(F)(F)F CHEMBL4636603 Kd 1.8 nM
COc1nc2ccc(C(O)(c3ccc(C#N)cc3)c3cncn3C)cc2c(C#N)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3949376 Kd 1.9 nM
COc1ccc2c(n1)CCN(C(=O)[C@H]1C[C@@H](CC(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4099342 IC50 1.9 nM
COc1ccc2c(c1)CCN(C(=O)Cc1cc(O)no1)[C@H]2C(=O)Nc1ccc(C(C)(C)C)c(F)c1 CHEMBL4061503 IC50 1.9 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC[C@@H]2CF)c(Cl)c1Cl)C(F)(F)F CHEMBL4648158 Kd 1.9 nM
O=S1(=O)CCC(O)(N[C@@H]2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4858617 EC50 1.9 nM
O=C(O)c1cc(F)c(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccnc23)cc1O CHEMBL5276516 IC50 1.9 nM
O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C(F)(F)F)n3ccccc23)cc1O CHEMBL3598148 EC50 2.0 nM
O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C3CC3)n3cccnc23)cc1O CHEMBL3596279 EC50 2.0 nM
CCN(CC)c1nc2ccc(C(O)(c3ccncc3)c3cncn3C)cc2c(Cl)c1-c1ccccc1 CHEMBL4062264 Kd 2.0 nM
CN(C)c1nc2ccc(C(O)(c3ccncc3)c3cncn3C)cc2c(Cl)c1-c1ccccc1 CHEMBL4059503 Kd 2.0 nM
COc1ccc2c(n1)CCN(C(=O)[C@H]1C[C@@H](C(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4073449 IC50 2.0 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CCS(=O)(=O)CC3)nc2C(C)(C)C)c2ccccc12 CHEMBL4127984 Kd 2.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(-c3cccc(Cl)c3)c(C(=O)c3ccccc3Cl)s2)cc1 CHEMBL3105692 IC50 2.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(-c3cc(C#N)cnc3OCC(F)(F)F)cs2)cc1 CHEMBL4167096 IC50 2.0 nM
Cc1c(C(F)(F)F)nc(-c2ccc(Cl)o2)n1-c1c(Cl)ccc(N2CC(C(N)=O)C2)c1Cl CHEMBL4587988 IC50 2.0 nM
O=C(O)[C@@H]1CCN(c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)C[C@H]1O CHEMBL4446417 IC50 2.0 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3Cl)c3ccccc23)cc1 CHEMBL3218921 IC50 2.0 nM
O=C(O)c1ccc(-n2cc(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c32)cc1 CHEMBL4567440 IC50 2.0 nM
CC(=O)N1CCN(c2ccc(CN3[C@@H](C)CC[C@H](c4cccs4)S3(=O)=O)c(F)c2)CC1 CHEMBL4519011 EC50 2.0 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4643996 Kd 2.0 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCCC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4644848 Kd 2.0 nM
CC(C)Cc1nc(-c2nnc(CC(C)(C)C(=O)O)o2)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(F)c1C(F)F CHEMBL4637003 Kd 2.0 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3c(c2)cc(Cc2ccc(Cl)cc2C(F)(F)F)n3CCF)cc1 CHEMBL5083464 EC50 2.0 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3c(c2)cc(Cc2ccccc2Cl)n3C(C)C)cc1 CHEMBL5086437 EC50 2.0 nM
CCc1ccccc1Cc1cc2cc(C(=O)NCc3ccc(S(=O)(=O)CC)cc3)ccc2n1C(C)C CHEMBL5081833 EC50 2.0 nM
COc1ccc2c(n1)CCN(C(=O)[C@H]1C[C@@H](C(=O)O)C1)[C@@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL5284935 IC50 2.0 nM
CC1(C)[C@@H]2CC[C@]1(c1ccnc(N3CCCCC3)n1)c1nnc(-c3c(F)cccc3F)cc12 CHEMBL5270756 IC50 2.0 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccnc23)c(F)c1 CHEMBL3558130 IC50 2.0 nM
O=C(NCc1ccccc1)c1c(NC(=O)C(F)(F)F)sc2c1CCCC2 CHEMBL5433149 IC50 2.07 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(N3CCC3)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1 CHEMBL3952340 Kd 2.1 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N3CC4(C3)CS(=O)(=O)C4)nc2CC2CCCCC2)c2ccccc12 CHEMBL4129599 Kd 2.1 nM
CCOc1ccccc1CN1CCc2cc(NC(=O)[C@H]3c4ccc(OC)nc4CCN3C(=O)CCCC(=O)O)ccc21 CHEMBL4446140 EC50 2.1 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC[C@@H]2C)c(Cl)c1Cl)C(F)(F)F CHEMBL4645155 Kd 2.1 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(C3(c4noc(-c5ccc(F)cc5)n4)CC3)c(Cl)c2)cc1 CHEMBL5277587 IC50 2.1 nM
O=C(CN1CCCCC1)Nc1sc2c(c1C(=O)NCc1ccccc1)CCCC2 CHEMBL5439193 IC50 2.15 nM
Cn1cncc1C(O)(c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1)c1cncn1C CHEMBL3953581 Kd 2.2 nM
CC(C)(C)NS(=O)(=O)c1ncc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4126216 Kd 2.2 nM
CC(C)(C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12)N1CCOCC1 CHEMBL4862214 EC50 2.2 nM
COc1nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4468588 Kd 2.3 nM
COC(C)(C)Cc1nc(-c2nnc(CC(C)(C)C(=O)O)o2)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(F)c1C(F)F CHEMBL4641039 Kd 2.3 nM
Cc1ncc(C(=O)Nc2cn3ccnc3c(CN3CCN(c4noc(C(C)(C)C)n4)[C@@H](C)C3)c2C)cn1 CHEMBL5205002 IC50 2.3 nM
CC1CCc2c(sc(NC(=O)c3ccccc3F)c2C(=O)N2CCN(C)CC2)C1 CHEMBL5420370 IC50 2.46 nM
COCC(C)(C)c1c(F)cc(NC(=O)[C@H]2c3ccc(OC)cc3CCN2C(=O)CCCC(=O)O)cc1F CHEMBL4062088 IC50 2.5 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC3CS(=O)(=O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4126991 Kd 2.5 nM
CCn1c(=O)n(CC2CC2)c(=O)c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc21 CHEMBL4226373 IC50 2.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(C)(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4644115 Kd 2.5 nM
C[C@@](O)(CS(C)(=O)=O)C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)nc3CC[C@@H]12 CHEMBL4760466 EC50 2.5 nM
CC(C)(O)CC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4784900 EC50 2.5 nM
C[C@@](O)(CS(C)(=O)=O)C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4779994 EC50 2.5 nM
O=C(NCCO)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4852430 EC50 2.5 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C3(C(F)(F)F)CC3)c3cccnc23)c(F)c1 CHEMBL5272739 IC50 2.5 nM
COc1ccc2c(n1)CCN(C(=O)[C@H]1C[C@H](C(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4081322 IC50 2.6 nM
CC(C)(O)CNC(=O)c1nc(CC2CCCCC2)c(-c2ccc(S(=O)(=O)NC(C)(C)C)c(Cl)c2C(F)F)s1 CHEMBL4127698 IC50 2.6 nM
CCCN(CC)C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4646821 Kd 2.6 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)c3nn[nH]n3)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4641370 Kd 2.6 nM
CCOc1nc2ccc(C(O)(c3ccc(OC)nc3)c3cncs3)cc2c(Cl)c1Cc1ccccc1 CHEMBL3891138 Kd 2.7 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2CC2CC(F)(F)C2)c2ccccc12)C(F)(F)F CHEMBL4130137 Kd 2.7 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3cc(CC(C)(C)C(=O)O)on3)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4649094 Kd 2.7 nM
COc1ccc(C(O)(c2ccc3nc(OC)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cncn2C)cn1 CHEMBL3968674 Kd 2.8 nM
COc1ccc2c(c1)OCCN(C(=O)c1cc(O)no1)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4217811 IC50 2.8 nM
Cc1cc2c(cc1C(F)(C(F)(F)F)C(F)(F)F)CC[C@H]1N(C(=O)[C@H]3CC[C@H](C(=O)O)CC3)CC[C@@]21S(=O)(=O)c1ccc(F)cc1 CHEMBL4741799 EC50 2.8 nM
N#Cc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cnc[nH]3)cc2c(C#N)c1Oc1ccccc1 CHEMBL3900139 Kd 2.9 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CC(F)(F)F CHEMBL4475244 Kd 2.9 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccccc3)c2)cc1 CHEMBL3109228 IC50 3.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccccc3F)c(F)c2)CC1 CHEMBL3581533 EC50 3.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598047 IC50 3.0 nM
CCN(CC)c1cc(-c2cc(C(N)=O)ccc2Cl)ccc1N(C)C(=O)c1c(F)cccc1Cl CHEMBL3596638 IC50 3.0 nM
CN(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(C(N)=O)ccc2Cl)cc1N1CCCCC1 CHEMBL3596639 IC50 3.0 nM
COc1ccc2c(c1)CCN(C(=O)CCCC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4087736 IC50 3.0 nM
COc1ccc2c(n1)CCN(C(=O)C[C@H]1C[C@H](C(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4074514 IC50 3.0 nM
CCS(=O)(=O)c1ccc([C@@H](NC(C)=O)C(=O)Nc2cc(-c3cccnc3OCc3ccc(OC(F)(F)F)cc3)cs2)cc1 CHEMBL4159819 IC50 3.0 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)cc1 CHEMBL4584679 IC50 3.0 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)cc1O CHEMBL3314007 IC50 3.0 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)c(F)c1 CHEMBL4449356 IC50 3.0 nM
CC(=O)N1CCN(c2ccc(CN3C[C@H](C)OC[C@H](c4ccccc4)S3(=O)=O)c(F)c2)CC1 CHEMBL4522912 EC50 3.0 nM
O=C(O)CC[C@H]1CN(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(-c3cccc(Cl)c3)ccc2O1 CHEMBL4851214 EC50 3.0 nM
C[C@H](C[C@H]1CN(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(-c3cc(F)ccc3F)ccc2O1)C(=O)O CHEMBL4870074 EC50 3.0 nM
Cc1ccc(C(NC(=O)Cc2ccc(OCc3c(C)noc3C)cc2)c2ccccc2)c(C)c1 CHEMBL5282505 IC50 3.0 nM
COc1ccc2c(n1)CCN(C(=O)[C@H]1C[C@H](CC(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4070717 IC50 3.1 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cnc(OCc3ccccc3)c(Cl)c2)cc1 CHEMBL4171857 IC50 3.1 nM
COc1ccc2c(c1)CCN(C(=O)CCCC(N)=O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4203255 IC50 3.1 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(NC(=O)CC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4648138 Kd 3.1 nM
CC(C)(O)CNC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4868491 EC50 3.1 nM
NS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3609409 pIC50 3.162 nM
CCS(=O)(=O)c1ccc(C(NC(=O)Cc2ccccc2)C(=O)Nc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)cc1 CHEMBL4458320 pIC50 3.162 nM
CC(=O)Nc1nc(C(C)C)c(-c2cnc(N(C)C(=O)c3c(F)cccc3Cl)c(N3CCCCC3)c2)s1 CHEMBL3598077 IC50 3.2 nM
COc1ccc2c(n1)CCN(C(=O)CCCC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4083828 IC50 3.2 nM
COc1ccc2c(n1)CCN(C(=O)CCCC(=O)O)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4100286 IC50 3.2 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc(CC(C)(C)O)o3)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4642733 Kd 3.2 nM
O=C(O)[C@H]1CC[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4cc(Br)c(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4759786 EC50 3.2 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(=O)CO)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598061 IC50 3.3 nM
Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(N3CCC3)c(Oc3ccc(C#N)cc3)c(Cl)c2c1 CHEMBL3897195 Kd 3.3 nM
COc1ccc2c(n1)CCN(C(=O)C[C@H]1C[C@@H](C(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4091605 IC50 3.3 nM
Cc1c(NC(=O)c2cccc(C#N)c2)ccc2c1c(C1CCN(C(=O)C3CCCC3)CC1)cn2C CHEMBL4290728 IC50 3.3 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)C3CN(C(C)=O)C3)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4532727 Kd 3.3 nM
[2H]C([2H])([2H])N(C(=O)c1c(Cl)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598052 IC50 3.4 nM
CCOc1nc2ccc(C(O)(c3ccc(OC)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 CHEMBL3956989 Kd 3.4 nM
Cn1cnc(CNC(=O)c2c(NC(=O)c3cccnc3)sc3c2CCCC3)n1 CHEMBL5413912 IC50 3.43 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1cc2ccccc2s1 CHEMBL3973915 Kd 3.5 nM
COc1ccc2c(c1)CCN(C(=O)COCC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4205112 IC50 3.5 nM
CC1CCCN1C(=O)c1c(NC(=O)c2cccnc2)sc2c1CCCC2 CHEMBL5435902 IC50 3.51 nM
COc1nc2ccc(C(O)(c3ccccc3)C3CCN(C(C)=O)CC3)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3964680 Kd 3.6 nM
CCn1c(=O)c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc2n(CC)c1=O CHEMBL4226313 IC50 3.6 nM
CCN(C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl)C1CC1 CHEMBL4644817 Kd 3.6 nM
CC(C)(O)C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4761772 EC50 3.6 nM
CC(C)n1c(=O)n(CC2CC2)c(=O)c2cc(NC(=O)N3CCOC(C(=O)Nc4ccc(C#N)c(Cl)c4)C3)ccc21 CHEMBL5202889 IC50 3.6 nM
CNC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4873930 EC50 3.7 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cnc3c(c2)CN(C[C@H]2CC[C@H](C(F)(F)F)CC2)[C@H]3C(C)C)nc1 CHEMBL5288854 Ki 3.7 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN(C[C@H]2CC[C@H](C(F)(F)F)CC2)[C@H]3C(C)C)nc1 CHEMBL4172726 IC50 3.7 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CCCCC1 CHEMBL3598049 IC50 3.8 nM
COc1ccc2c(c1)CCN(C(=O)CC(C)CC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4217478 IC50 3.8 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1OCC1CC1 CHEMBL4457391 Kd 3.8 nM
O=C(O)c1ccc(-n2nc(C(=O)c3c(Cl)cccc3Cl)c3ccccc32)cc1 CHEMBL4540580 IC50 3.8 nM
CN1CCN(C(=O)c2c(NC(=O)c3ccccc3F)sc3c2CCC(C(C)(C)C)C3)CC1 CHEMBL5425785 IC50 3.8 nM
COc1nc2ccc(C(O)(c3ccc(F)cc3)C3CCN(C(C)=O)CC3)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3944463 Kd 3.9 nM
CCn1c(=O)c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc2n(CC2CC2)c1=O CHEMBL4225541 IC50 3.9 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CN1CC(C(F)(F)F)C1 CHEMBL4438967 Kd 3.9 nM
CCN(CCCF)C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4637518 Kd 3.9 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3noc(C(C)(C)O)n3)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4634974 Kd 3.9 nM
CC(C)(O)C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)nc3CC[C@@H]12 CHEMBL4750756 EC50 3.9 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccc(F)cc3C#N)c(Cl)c2)cc1 CHEMBL3609411 pIC50 3.981 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3609407 pIC50 3.981 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(C)c(-c3ccccc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3609406 pIC50 3.981 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3OC(F)(F)F)c(-c3cncnc3)c2)cc1 CHEMBL3609404 pIC50 3.981 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3cccc(C(F)(F)F)c3)c2)cc1 CHEMBL3109234 IC50 4.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(Cl)cc3)c2)cc1 CHEMBL3109230 IC50 4.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccccc3Cl)c(F)c2)CC1 CHEMBL3581539 EC50 4.0 nM
C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1cc(F)c(C(CO)CC2COC2)cc1F CHEMBL3632716 IC50 4.0 nM
CC(C)CN(Cc1ccc(O[C@H]2C[C@H]3CC[C@@H](C2)N3S(C)(=O)=O)cc1)S(=O)(=O)Cc1ccccc1 CHEMBL3956592 IC50 4.0 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1 CHEMBL3927166 Kd 4.0 nM
COc1ccc2c(c1)CCN(C(=O)CCCC(=O)O)[C@H]2C(=O)Nc1cc(F)c(C(C)(C)C)c(F)c1 CHEMBL4093539 IC50 4.0 nM
Cc1c(CC(C)C)nc(-c2ccc(Cl)o2)n1-c1c(Cl)ccc(N2CC(C(=O)O)C2)c1Cl CHEMBL4446191 IC50 4.0 nM
Cc1c(C(F)(F)F)nc(-c2ccc(Cl)o2)n1-c1c(Cl)cccc1Cl CHEMBL4562740 IC50 4.0 nM
Cc1c(CC(C)C)nc(-c2ccco2)n1-c1c(Cl)cccc1Cl CHEMBL4580481 IC50 4.0 nM
O=C(O)C1CC=C(c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)CC1 CHEMBL4547016 IC50 4.0 nM
O=C(O)c1ccc(-n2cc(C(=O)c3c(Cl)cccc3Cl)c3cccc(F)c32)c(F)c1 CHEMBL4455132 IC50 4.0 nM
CCS(=O)(=O)c1cnc(CNc2nc3cnc(-c4c(C)ncnc4C4CC4)nc3n([C@@H](C)C3CC3)c2=O)s1 CHEMBL4776548 IC50 4.0 nM
C[C@@H](C[C@H]1CN(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(-c3cc(F)ccc3F)ccc2O1)C(=O)O CHEMBL4859771 EC50 4.0 nM
CCCCCn1c(-c2ccc(NC(=O)Cc3ccc(S(=O)(=O)CC)cc3)cc2)nc2ccc(C)cc21 CHEMBL5279688 IC50 4.0 nM
COc1ccc(C(O)(c2ccc3nc(N(C)C)c(Oc4ccccc4)c(Cl)c3c2)c2cncn2C)cn1 CHEMBL3925882 Kd 4.1 nM
COc1ccc2c(c1)CCN(C(=O)/C=C/C(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4209940 IC50 4.1 nM
CC(C)C(=O)N1CCC(c2cn(C)c3ncc(NC(=O)c4cccc(C#N)c4)c(C(F)(F)F)c23)CC1 CHEMBL4278903 IC50 4.1 nM
CCOc1ccccc1CN1CCc2cc(NC(=O)[C@H]3c4ccc(OC)nc4CCN3C(C)=O)ccc21 CHEMBL4448684 EC50 4.1 nM
Cc1cc(C(O)(c2ccc(C(F)(F)F)nc2)c2cncn2C)cc2c(C#N)c(Cc3ccc(-n4cccn4)cc3)c(C#N)nc12 CHEMBL3959062 Kd 4.2 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(C#N)c(Oc3ccc(Cl)cc3)c(C(F)(F)F)c2c1 CHEMBL3933074 Kd 4.2 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N3CC4(CCS(=O)(=O)CC4)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL3314001 Kd 4.2 nM
COc1ccc2c(c1)CCN(C(=O)CCC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4205579 IC50 4.2 nM
CS(=O)(=O)c1ccc(CNC(=O)c2cc3c(s2)C2(CCN(Cc4ccccc4Cl)CC2)OCC3)cc1 CHEMBL5081557 Ki 4.2 nM
Cn1cncc1C(O)(c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1)c1cncs1 CHEMBL3892661 Kd 4.3 nM
COc1ccc([C@H](C(=O)Nc2cc(F)c([Si](C)(C)C)c(F)c2)N(C)C(=O)c2cc(O)no2)cc1 CHEMBL4213410 IC50 4.3 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3nnc([C@H]4C[C@H](C(=O)O)C4)o3)nc2CC2CCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4634072 Kd 4.3 nM
CCn1c(C(C)(C)Oc2ccc(F)cc2F)nc2cc(NC(=O)Cc3ccc(S(=O)(=O)CC)cc3)ccc21 CHEMBL5270326 IC50 4.3 nM
COc1nc2c(OC)cc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3923997 Kd 4.4 nM
COc1ccc2c(n1)CCN(C(=O)N1CC(CC(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4094983 IC50 4.4 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(C(C)(C)C(=O)Nc3ccccc3F)cc2)cc1 CHEMBL4286190 IC50 4.4 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCCC(C)(C)C#N)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4644205 Kd 4.4 nM
CC(C)Oc1ccc2c(c1)N(CCc1ccc(NC(=O)Cc3ccc(S(C)(=O)=O)cc3)cc1)CCO2 CHEMBL4870796 EC50 4.4 nM
CC(Oc1ccc2c(c1)N(CCc1ccc(NC(=O)Cc3ccc(S(C)(=O)=O)cc3)cc1)CCO2)C(F)(F)F CHEMBL4866533 EC50 4.4 nM
COc1ccc(C(O)(c2ccc3nc(Cl)c(Cc4ccccc4)c(Cl)c3c2)c2cncs2)cn1 CHEMBL3925143 Kd 4.5 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(C#N)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3957370 Kd 4.5 nM
COc1ccc2c(c1)CCN(C(=O)CC(C)(O)CC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4210540 IC50 4.5 nM
CC(=O)NCC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4877606 EC50 4.5 nM
CC1CCN(CC(=O)Nc2sc3c(c2C(=O)NCc2ccccc2)CCCC3)CC1 CHEMBL5401795 IC50 4.5 nM
CCn1c2ccc(C(=O)NCc3ccc(S(=O)(=O)CC)cc3)cc2c2ccc(OC(C)C)cc21 CHEMBL5425541 EC50 4.5 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc(CCN3CCOc4ccc(OC(C)C)cc43)cc2)nc1 CHEMBL4874284 EC50 4.6 nM
CC[C@H](NC(=O)c1cc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)cc(C2(C)CC2)c1)C(F)(F)F CHEMBL4129790 IC50 4.7 nM
CCN(CCC(F)(F)F)C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4639646 Kd 4.7 nM
CS(=O)(=O)N[C@H]1CC[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(OCc5c(F)cccc5C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4634701 EC50 4.7 nM
Cn1cc(C2CCN(C(=O)C3CCCC3)CC2)c2c(C(F)(F)F)c(NC(=O)c3cccc(C#N)c3)cnc21 CHEMBL5265977 IC50 4.7 nM
[2H]C([2H])([2H])N(C(=O)c1c(C)cccc1F)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598053 IC50 4.8 nM
COc1nc2c(C)cc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3937236 Kd 4.8 nM
COc1ccc2c(c1)CCN(C(=O)CCCC(=O)O)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4072831 IC50 4.8 nM
CC(C)(C)NC(=O)c1cc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)cc(C2(C)CC2)c1 CHEMBL4126534 Kd 4.8 nM
C[C@H](NS(=O)(=O)c1cc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)cc(C(C)(C)C)c1)C(F)(F)F CHEMBL4128427 Kd 4.8 nM
CCn1c2ccccc2c2cc(NC(=O)CCCC(=O)Nc3ccc(C#N)cc3)ccc21 CHEMBL4228650 IC50 4.8 nM
Cn1cc(C2CCN(C(=O)C3CCCC3)CC2)c2cc(NC(=O)c3cc(C#N)ccn3)cnc21 CHEMBL4283051 IC50 4.8 nM
COc1nc2ccc(C(O)(c3cnc(C)n3C)C3CN(C(C)=O)C3)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1 CHEMBL4459199 Kd 4.8 nM
CC(=O)Nc1cc(-c2ccc(N(C)C(=O)c3c(F)cccc3Cl)c(N3CC4CC4C3)c2)n(C(C)C)n1 CHEMBL3598051 IC50 4.9 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC=O)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598055 IC50 4.9 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(=O)CC)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598056 IC50 4.9 nM
CC(CC(=O)Nc1ccc(C#N)c(Cl)c1)CC(=O)Nc1ccc2c(c1)c(=O)n(CC1CC1)c(=O)n2CC1CC1 CHEMBL4228907 IC50 4.9 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(C(F)(F)F)cc3)c2)cc1 CHEMBL3109227 IC50 5.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(=O)C3CC3)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598057 IC50 5.0 nM
O=S1(=O)[C@H](c2ccccc2)CCCCN1Cc1cc(F)c(N2C[C@@H]3[C@H](C2)[C@H]3n2cnnc2)cc1F CHEMBL3634609 IC50 5.0 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3968603 Kd 5.0 nM
COc1nc2ccc(C(O)(c3cnnn3C)c3cnnn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3952077 Kd 5.0 nM
COc1nc2ccc(C(O)(c3ccncc3)c3cncn3C)cc2c(Cl)c1-c1ccccc1 CHEMBL4088364 Kd 5.0 nM
Cn1cc(C2CCN(C(=O)C3CCCCC3)CC2)c2cc(NC(=O)c3cc(C#N)ccn3)ccc21 CHEMBL4281109 IC50 5.0 nM
Cn1cc(C2CCN(C(=O)C3CCCC3)CC2)c2cc(NC(=O)c3cc(C#N)ccn3)ccc21 CHEMBL4287715 IC50 5.0 nM
Cc1c(C2(C(F)(F)F)CC2)nc(C2CC2)n1-c1c(Cl)ccc(N2CC3(CC(C(=O)O)C3)C2)c1Cl CHEMBL4513808 IC50 5.0 nM
Cc1c(C2(C(F)(F)F)CC2)nc(-c2ccc(Cl)o2)n1-c1c(Cl)ccc(NCC(C)(C)C(=O)O)c1Cl CHEMBL4466072 IC50 5.0 nM
Cc1c(Cc2ccccc2)nc(-c2ccco2)n1-c1c(Cl)cccc1Cl CHEMBL4554462 IC50 5.0 nM
O=C(O)c1ccc(-n2cc(C(=O)c3c(Cl)cccc3Cl)c3ccccc32)cc1O CHEMBL4454020 IC50 5.0 nM
CCN(CC)C(=O)c1nc(-c2nnc(C(C)(C)O)o2)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4648849 Kd 5.0 nM
CC(C)(O)CNC(=O)[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4753822 EC50 5.0 nM
COCC(=O)N1CCC(C(=O)N2C[C@@H](c3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)[C@@](C)(c3ccc(F)cc3)C2)CC1 CHEMBL4783255 EC50 5.0 nM
O=C(O)C1(C[C@H]2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)c3cc(-c4cc(F)ccc4F)ccc3O2)CCOCC1 CHEMBL4868437 EC50 5.0 nM
Cc1ccc([C@@H](NC(=O)Cc2ccc3oc(C(O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1 CHEMBL5276895 IC50 5.0 nM
CCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc3c(c2)C(O)CC(CC2CCOCC2)O3)cc1 CHEMBL5282046 IC50 5.0 nM
CCc1ccc(N(C2CCC2)S(=O)(=O)c2ccc3c(c2)C(O)CC(C2CCOCC2)O3)cc1 CHEMBL5285102 IC50 5.0 nM
Cc1ccc([C@H](NC(=O)Cc2ccc3oc([C@@H](O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1 CHEMBL5280104 IC50 5.0 nM
CS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3609408 pIC50 5.012 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3OC(F)(F)F)c(-c3ccno3)c2)cc1 CHEMBL3609403 pIC50 5.012 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3OC(F)(F)F)c(C)c2)cc1 CHEMBL3609399 pIC50 5.012 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3Cl)c(Cl)c2)cc1 CHEMBL3609391 pIC50 5.012 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C2CCCC2)cc1N1CC2CC2C1 CHEMBL3598070 IC50 5.1 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc(CCN3CCOc4ccc(OC(C)C)cc43)c(Cl)c2)nc1 CHEMBL4865131 EC50 5.1 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C2CCC2)cc1N1CC2CC2C1 CHEMBL3598071 IC50 5.2 nM
COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(S(C)(=O)=O)cc1 CHEMBL3947232 Kd 5.3 nM
Cn1cncc1C(O)(c1ccnc(F)c1)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1 CHEMBL4209998 Kd 5.3 nM
COc1ccc2c(c1)CCN(C(=O)c1cc(O)no1)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4206093 IC50 5.3 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CC(F)(F)C[C@@H]2C)c(C(F)F)c1F)C(F)(F)F CHEMBL4646799 Kd 5.3 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCCc4ccc(C=C(C)C)cc43)cc2)cc1 CHEMBL4875850 EC50 5.3 nM
COc1nc2ccc([C@@](O)(c3ccccc3)C3CCN(C(C)=O)CC3)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL4802042 qKD 5.3 nM
CCN(CC)C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl CHEMBL4643735 Kd 5.4 nM
CC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4864029 EC50 5.4 nM
[2H]C([2H])([2H])N1C(=O)[C@@H](F)C[C@@H]1C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4870806 EC50 5.4 nM
Cn1cc(C2CCN(C(=O)C3CCCC3)CC2)c2cc(NC(=O)c3cccc(C#N)c3)ccc21 CHEMBL4291727 IC50 5.5 nM
C[C@](O)(CS(C)(=O)=O)C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4741364 EC50 5.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C2CCCCC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4127892 Kd 5.6 nM
COc1ccc2c(c1)CCN(C(=O)CC(C)(C)CC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4210727 IC50 5.6 nM
NC(=O)N1CCC(C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(OCc5c(F)cccc5C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4642011 EC50 5.6 nM
CCn1c2ccc(OC(C)C)cc2c2cc(C(=O)NCc3ccc(S(=O)(=O)CC)cn3)ccc21 CHEMBL5410038 EC50 5.6 nM
CCC1CCN(C(=O)c2c(NC(=O)c3cccnc3)sc3c2CCCC3)C1 CHEMBL5394581 IC50 5.66 nM
Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Oc3ccccc3)c(C#N)c2c1 CHEMBL3940425 Kd 5.7 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c(Cl)c1 CHEMBL4126040 Kd 5.7 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1CN1CCC(F)(F)CC1 CHEMBL4471936 Kd 5.7 nM
COc1nc2c(C)cc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3975460 Kd 5.8 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2cc3c(s2)C2(CCN([C@H](C)c4cnc(C(F)(F)F)nc4)CC2)O[C@@H](C)C3)cc1 CHEMBL5089797 Ki 5.89 nM
CCn1c2c(c3cc(NC(=O)CC(C)CC(=O)Nc4ccc(C#N)cc4)ccc31)CCCC2 CHEMBL4227433 IC50 5.9 nM
CCCN(Cc1ccc(NC(=O)Cc2ccc(S(=O)(=O)CC)cc2)cc1)Cc1ccc(C(F)(F)F)cc1 CHEMBL3109329 IC50 6.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(Cl)c(Cl)c3)c2)cc1 CHEMBL3109324 IC50 6.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(Cl)cc3Cl)c2)cc1 CHEMBL3109235 IC50 6.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccccc3C(F)(F)F)c2)cc1 CHEMBL3109233 IC50 6.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(OC(C)C)cc3)c2)cc1 CHEMBL3109232 IC50 6.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(C#N)cc3)c2)cc1 CHEMBL3109231 IC50 6.0 nM
CC(C)CN(Cc1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1 CHEMBL3361052 IC50 6.0 nM
CC(C)CN(Cc1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(NC2CCN(S(C)(=O)=O)CC2)cc1 CHEMBL3361050 IC50 6.0 nM
CC(C)CN(Cc1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)Cc1ccccc1 CHEMBL3314036 IC50 6.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cc(Cl)cc(Cl)c3)c(F)c2)CC1 CHEMBL3581543 IC50 6.0 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(=O)NC)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598063 IC50 6.0 nM
CC(C)CN(Cc1ccc(NC2CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)Cc1ccccc1 CHEMBL3894302 IC50 6.0 nM
Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(N3CCC3)c(-c3ccccc3)c(Cl)c2c1 CHEMBL4097986 Kd 6.0 nM
CCS(=O)(=O)c1ccc(C(NC(C)=O)C(=O)Nc2cc(-c3cccnc3OCc3ccc(OC(F)(F)F)cc3)cs2)cc1 CHEMBL4176887 IC50 6.0 nM
O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cnccc23)c(F)c1 CHEMBL4456513 IC50 6.0 nM
CC(=O)N1CCN(c2ccc(CN3CCCC[C@H](c4ccccc4)S3(=O)=O)c(F)c2)CC1 CHEMBL4560046 EC50 6.0 nM
Cc1ccc(NC(=O)C[C@H](CCC(=O)[O-])c2noc(-c3cc(C(F)(F)C(C)(C)C)on3)c2C2CC2)c(Cl)c1 CHEMBL4521766 EC50 6.0 nM
CC(C)(C)C(F)(F)c1cc(-c2onc([C@@H](CCC(=O)[O-])CC(=O)Nc3ccc(F)cc3Cl)c2C2CC2)no1 CHEMBL4541987 EC50 6.0 nM
CC(C)(O)CC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)nc3CC[C@@H]12 CHEMBL4800380 EC50 6.0 nM
O=C(O)CC[C@H]1CN(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(-c3cccc(F)c3)ccc2O1 CHEMBL4849989 EC50 6.0 nM
COc1cc(F)cc(-c2ccc3c(c2)N(S(=O)(=O)c2cccc(C(F)(F)F)c2)C[C@H](CCC(=O)O)O3)c1 CHEMBL4862004 EC50 6.0 nM
O=C(O)C1(C[C@H]2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)c3cc(-c4cc(F)cc(OC(F)F)c4)ccc3O2)COC1 CHEMBL4856642 EC50 6.0 nM
Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc3c(c2)C(O)CC(C2CCOCC2)O3)c(C)c1 CHEMBL5285941 IC50 6.0 nM
COc1ccc(C(O)(c2ccc3nc(Cl)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cncn2C)cn1 CHEMBL3894064 Kd 6.1 nM
CC(C)(CCO)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4127587 Kd 6.1 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NC3CCS(=O)(=O)CC3)nc2CC2CC2)c2ccccc12)C(F)(F)F CHEMBL4129034 IC50 6.1 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1OC(C)C CHEMBL4434891 Kd 6.1 nM
CCn1c2ccc(OC3CCC3)cc2c2cc(C(=O)NCc3ccc(S(=O)(=O)CC)cc3)ccc21 CHEMBL5413785 EC50 6.1 nM
CC(=O)Nc1cc(-c2cnc(N(C)C(=O)c3c(F)cccc3Cl)c(N3CCCCC3)c2)n(C(C)C)n1 CHEMBL3598076 IC50 6.2 nM
COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(C#N)cc1 CHEMBL3965309 Kd 6.2 nM
CON(C)c1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3974597 Kd 6.3 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(-c3cccc(Cl)c3)c(C(=O)c3ccccc3F)s2)cc1 CHEMBL3105670 pIC50 6.31 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccc(Cl)cc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3609415 pIC50 6.31 nM
Cc1cc(NC(=O)Cc2ccc(S(C)(=O)=O)cc2)ccc1-c1ccc(Cl)cc1OC(F)(F)F CHEMBL3609413 pIC50 6.31 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3C#N)c(Cl)c2)cc1 CHEMBL3609410 pIC50 6.31 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)(F)F)c(C#N)c2)cc1 CHEMBL3609405 pIC50 6.31 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3OC(F)(F)F)c(C(F)(F)F)c2)cc1 CHEMBL3609400 pIC50 6.31 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3C(F)(F)F)c(Cl)c2)cc1 CHEMBL3609392 pIC50 6.31 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2CC2CC2)cc1N1CC2CC2C1 CHEMBL3598074 IC50 6.4 nM
COc1ccc2c(n1)CCN(C(=O)C1CN(CC(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C CHEMBL4085443 IC50 6.4 nM
Cn1cncc1C(O)(c1ccnc(C(F)(F)F)c1)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1 CHEMBL4218386 Kd 6.4 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)nc1 CHEMBL3901412 Kd 6.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)(F)CC2)c(C(F)(F)F)c1F)C(F)(F)F CHEMBL4647352 Kd 6.5 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(CC(C)(C)C(=O)O)nc2CC2CCC2)c(Cl)c1)C(F)(F)F CHEMBL4649863 Kd 6.5 nM
CCOc1nc2ccc(C(O)(c3cncs3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3936717 Kd 6.6 nM
COc1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(F)cc1 CHEMBL4101047 Kd 6.6 nM
COc1ccc2c(c1)CCN(C(=O)CCCCC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4214337 IC50 6.6 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCCc4ccc(OC5COC5)cc43)cc2)cc1 CHEMBL4849340 EC50 6.6 nM
CS(=O)(=O)N1CCC(N[C@@H]2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4867702 EC50 6.7 nM
C[C@H]1CC[C@H](c2ccccc2)S(=O)(=O)N1Cc1ccc(N2CCC3(CC2)C(=O)N(C)C(=O)N3C)cc1F CHEMBL3632715 IC50 6.9 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(NCCC(C)(C)O)nc2C(=O)N2CCC(F)CC2)c(Cl)c1Cl)C(F)(F)F CHEMBL4636509 Kd 6.9 nM
CC(C)CN(Cc1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(C(=O)C2CCN(S(C)(=O)=O)CC2)cc1 CHEMBL3361053 IC50 7.0 nM
CC(C)CN(c1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(NC2CCN(S(C)(=O)=O)CC2)cc1 CHEMBL3361051 EC50 7.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3ccc(Cl)c(Cl)c3)c(F)c2)CC1 CHEMBL3314035 IC50 7.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccc(F)cc3)c(F)c2)CC1 CHEMBL3581537 EC50 7.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Oc3ccccc3)c(F)c2)CC1 CHEMBL3657608 IC50 7.0 nM
CC(=O)N1CCN(c2ccc(CN(CC(C)C)S(=O)(=O)Cc3ccccc3)c(F)c2)CC1 CHEMBL3936911 IC50 7.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(-c3cccnc3OCc3ccc(OC(F)(F)F)cc3)cs2)cc1 CHEMBL4163215 IC50 7.0 nM
CCS(=O)(=O)c1ccc(C(NC(C)=O)C(=O)Nc2cc(-c3cc(C#N)cnc3OCC(F)(F)F)cs2)cc1 CHEMBL4163193 IC50 7.0 nM
CCS(=O)(=O)c1ccc(C(NC(C)=O)C(=O)Nc2cc(-c3cccnc3OCc3ccccc3)cs2)cc1 CHEMBL4173908 IC50 7.0 nM
Cc1c(C(F)(F)F)nc(-c2ccc(Cl)o2)n1-c1c(Cl)ccc(N2CC(CC(=O)O)C2)c1Cl CHEMBL4444848 IC50 7.0 nM
CCN1C[C@H]2N(C(=O)[C@H]3CC[C@H](C(=O)O)CC3)CC[C@@]2(S(=O)(=O)c2ccc(F)cc2)c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc21 CHEMBL4527982 EC50 7.0 nM
O=C(O)[C@H]1CC[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4445959 EC50 7.0 nM
O=C(O)C1CCN(c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)CC1 CHEMBL4579976 IC50 7.0 nM
Cc1ccc([C@@H](NC(=O)Cc2ccc3oc([C@@H](O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1 CHEMBL3977048 IC50 7.0 nM
CC(=O)N1CCN(c2ccc(CN3[C@@H](C)CC[C@H](c4cccc(Cl)c4)S3(=O)=O)c(F)c2)CC1 CHEMBL4586831 EC50 7.0 nM
Cc1ccc(NC(=O)C[C@H](CCC(=O)[O-])c2noc(-c3cc(C(F)(F)C(C)C)on3)c2C2CC2)c(Cl)c1 CHEMBL4570149 EC50 7.0 nM
Cc1ccc(NC(=O)C[C@H](CCC(=O)[O-])c2noc(-c3cc(CC(C)(C)C)on3)c2C2CC2)c(Cl)c1 CHEMBL4574815 EC50 7.0 nM
CC(C)(C)C(F)(F)c1cc(-c2onc([C@@H](CCC(=O)[O-])CC(=O)Nc3ccc(Cl)cc3F)c2C2CC2)no1 CHEMBL4593726 EC50 7.0 nM
C[C@H]1C[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4cccc(F)c4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC[C@H]1C(=O)O CHEMBL4641394 EC50 7.0 nM
C[C@@H]1C[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC[C@H]1C(=O)O CHEMBL4641486 EC50 7.0 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CCC(F)(F)C2)c(Cl)c1Cl)C(F)(F)F CHEMBL4647147 Kd 7.0 nM
O=C(O)[C@H]1CC[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(OCc5c(F)cccc5C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4644223 EC50 7.0 nM
O=C1[C@H](F)C[C@@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)N1Cc1ccc(F)cc1 CHEMBL4777864 EC50 7.0 nM
CCS(=O)(=O)c1ccc(CNc2nc3cnc(-c4c(C)ncnc4C4CC4)nc3n([C@@H](C)C3CC3)c2=O)nc1 CHEMBL4787938 IC50 7.0 nM
COc1ccc(Oc2c(Cl)ccc(C(=O)NCc3ccc(S(N)(=O)=O)cc3)c2Cl)cc1C(C)C CHEMBL4783854 EC50 7.0 nM
CCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc3c(c2)C(O)C[C@@H](C2CCOCC2)O3)cc1 CHEMBL5278608 IC50 7.0 nM
CC(C)CN(c1cccc(F)c1)S(=O)(=O)c1ccc2c(c1)C(O)CC(C1CCOCC1)O2 CHEMBL5280302 IC50 7.0 nM
CCc1ccc(N(CC2CCC2)S(=O)(=O)c2ccc3c(c2)C(O)CC(C2CCOCC2)O3)cc1 CHEMBL5280977 IC50 7.0 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc(CCN3CCOc4ccc(CC(C)C)cc43)cc2)nc1 CHEMBL4857697 EC50 7.1 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CN(Cc3ccccc3)CC3CCC3)cc2)cc1 CHEMBL5083860 EC50 7.1 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3cccc(C#N)c3)c(Cl)c2)cc1 CHEMBL5424705 XC50 7.1 nM
CCN(CC)c1nc2ccc(C(O)(c3cncs3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 CHEMBL3960552 Kd 7.2 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCOc4ccc(OC(C)C)cc43)cc2)cc1 CHEMBL4855566 EC50 7.3 nM
CS(=O)(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4873153 EC50 7.3 nM
COc1ccc(-c2nc(Nc3ccc(NC(C)=O)cc3)nc(Oc3c(Cl)cccc3Cl)n2)cc1 CHEMBL5419000 IC50 7.3 nM
O=C(N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12)C1(O)CCOCC1 CHEMBL4863937 EC50 7.4 nM
O=C(O)c1ccc(/C=C/c2c(-c3c(Cl)cccc3C(F)(F)F)noc2-c2cc[nH]c2)cc1 CHEMBL5200206 IC50 7.4 nM
COc1ccc([C@H](C(=O)Nc2cc(F)c([Si](C)(C)C)c(F)c2)N(C)C(=O)CCC(=O)O)cc1 CHEMBL4210449 IC50 7.5 nM
CCC1Oc2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc2N(CC)C1=O CHEMBL4225105 IC50 7.5 nM
CCn1c2ccccc2c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)cc3)ccc21 CHEMBL4224762 IC50 7.5 nM
CC(C)Oc1ccc2c(c1)N(CCc1ccc(C(=O)NCc3ccc(S(C)(=O)=O)cn3)cc1)CCO2 CHEMBL4855243 EC50 7.5 nM
COc1ccc2c(c1)CCN(C(=O)CC1SC(=O)NC1=O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4205062 IC50 7.6 nM
Cc1c(NC(=O)c2ccc(Cl)c(C#N)c2)cnc2c1c(C1CCN(C(=O)C(C)C)CC1)cn2C CHEMBL4283312 IC50 7.6 nM
OC(c1cccnc1)(c1cccc(Cl)c1)c1ccc2nc(Cl)c(Cc3cccc(Cl)c3)c(Cl)c2c1 CHEMBL3921489 Kd 7.7 nM
COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL3925105 Kd 7.7 nM
O=C(C1CCS(=O)(=O)CC1)N1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(OCc4c(F)cccc4C(F)(F)F)cc3CC[C@@H]12 CHEMBL4648410 EC50 7.7 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc(CCN3CCCc4ccc(OC5COC5)cc43)cc2)nc1 CHEMBL4868594 EC50 7.7 nM
CCn1c2ccc(OC(C)C)cc2c2cc(C(=O)NCc3ccc(S(=O)(=O)CC)cc3)ccc21 CHEMBL5417488 EC50 7.7 nM
COc1ccc2c(c1)CCN(C(=O)CN(C)CC(=O)O)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1 CHEMBL4213861 IC50 7.8 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCCc4ccc(C5CC5)cc43)cc2)cc1 CHEMBL4870621 EC50 7.8 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCOc4ccc(OC(C)C)cc43)c(F)c2)cc1 CHEMBL4869521 EC50 7.8 nM
CCCN(Cc1ccccc1)Cc1ccc(NC(=O)Cc2ccc(S(=O)(=O)CC)cc2)cc1 CHEMBL3109325 EC50 7.8 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3c(c2)c2cc(OC(C)C)ccc2n3CCF)cc1 CHEMBL5429680 EC50 7.8 nM
Cc1cc(C(O)(c2ccc(C#N)cc2)c2cncn2C)cc2c(C#N)c(Cc3ccc(-n4cccn4)cc3)c(C#N)nc12 CHEMBL3964841 Kd 7.9 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2CC2CC2)c2ccccc12)C(F)(F)F CHEMBL4128076 IC50 7.9 nM
Cn1cc(C2CCN(C(=O)C3CCCC3)CC2)c2cc(NC(=O)c3cccc(C#N)c3)cnc21 CHEMBL4282848 IC50 7.9 nM
CCc1ccc(-c2c(Cl)cc(NC(=O)Cc3ccc(S(=O)(=O)CC)cc3)cc2Cl)cc1C#N CHEMBL5417539 EC50 7.9 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(-c3cccc(Cl)c3)c(C(=O)c3cccc(Cl)c3)s2)cc1 CHEMBL3105669 pIC50 7.943 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3cccc(Cl)c3)c(C(=O)c3ccccc3Cl)s2)cc1 CHEMBL3105681 pIC50 7.943 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3ccccc3)c(Oc3ccc(Cl)cc3)s2)cc1 CHEMBL3605084 pIC50 7.943 nM
CS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccc(Cl)cc3OC(F)(F)F)c(Cl)c2)cc1 CHEMBL3609414 pIC50 7.943 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3OC(F)(F)F)cc2)cc1 CHEMBL3609397 pIC50 7.943 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(F)cc3)c2)cc1 CHEMBL3109229 IC50 8.0 nM
CC(C)CN(c1cccc(F)c1)S(=O)(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1 CHEMBL3361057 IC50 8.0 nM
CCN(CC)c1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccc(F)cc1 CHEMBL3934890 Kd 8.0 nM
O=C(O)[C@H]1CC[C@](O)(C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4469783 EC50 8.0 nM
CC(=O)N1CCN(c2ccc(CN3[C@@H](C)COC[C@H](c4ccccc4)S3(=O)=O)c(F)c2)CC1 CHEMBL4573492 EC50 8.0 nM
Cc1ccc(NC(=O)C[C@H](CCC(=O)[O-])c2noc(-c3cc(CCC(C)C)on3)c2C2CC2)c(Cl)c1 CHEMBL4550501 EC50 8.0 nM
Cc1ccc(NC(=O)C[C@H](CCC(=O)[O-])c2noc(-c3cc(C(F)(F)CC(C)C)on3)c2C2CC2)c(Cl)c1 CHEMBL4577230 EC50 8.0 nM
CCS(=O)(=O)c1ccc(CNc2nc3cnc(-c4c(OC)ncnc4C4CC4)nc3n([C@@H](C)C3CC3)c2=O)nc1 CHEMBL4744994 IC50 8.0 nM
COc1cccc(-c2ccc3c(c2)N(S(=O)(=O)c2cccc(C(F)(F)F)c2)C[C@H](CCC(=O)O)O3)c1 CHEMBL4860324 EC50 8.0 nM
O=C(O)CC[C@H]1CN(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(-c3cc(F)ccc3F)ccc2O1 CHEMBL4864871 EC50 8.0 nM
O=C(O)C1(C[C@H]2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)c3cc(-c4cc(F)cc(OC(F)F)c4)ccc3O2)CCOCC1 CHEMBL4869567 EC50 8.0 nM
Cc1nc(N2CCOCC2)ccc1N(CC(C)C)S(=O)(=O)c1ccc2c(c1)C(=O)CC(C1CCOCC1)O2 CHEMBL5078327 IC50 8.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CN(Cc3ccccc3)CC3CC3)c(Cl)c2)cc1 CHEMBL5092600 EC50 8.0 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3c(c2)cc(Cc2ccc(Cl)cc2C(F)(F)F)n3C(C)C)cc1 CHEMBL5090608 EC50 8.0 nM
CCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc3c(c2)C(O)CC(C2CCOCC2)O3)cc1 CHEMBL5272275 IC50 8.0 nM
CCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc3c(c2)C(O)C[C@H](C2CCOCC2)O3)cc1 CHEMBL5291188 IC50 8.0 nM
CC(C)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc2c(c1)C(O)CC(C1CCOCC1)O2 CHEMBL5282428 IC50 8.0 nM
COc1nc2ccc([C@](O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1 CHEMBL5279266 IC50 8.0 nM
Cc1cccc2c(C(=O)c3ccccc3Cl)cn(-c3ccc(C(=O)O)cc3F)c12 CHEMBL4551954 IC50 8.1 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(C(C)(C)C(=O)Nc3cc(Cl)ccn3)cc2)cc1 CHEMBL4286603 IC50 8.2 nM
COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1OCC1CC1(F)F CHEMBL4568486 Kd 8.2 nM
CCCN(Cc1ccccc1)Cc1c(Cl)cc(NC(=O)Cc2ccc(S(=O)(=O)CC)cc2)cc1Cl CHEMBL5075133 EC50 8.2 nM
CCN(CC)c1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 CHEMBL3973380 Kd 8.3 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C2CC2)cc1N1CC2CC2C1 CHEMBL3598075 IC50 8.4 nM
COc1nc2c(C)cc(C(O)(c3cncn3C)c3cncn3C)cc2c(Cl)c1Cc1ccc(S(C)(=O)=O)cc1 CHEMBL3927010 Kd 8.4 nM
O=C(N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)nc3CC[C@@H]12)C1CCS(=O)(=O)CC1 CHEMBL4744956 EC50 8.4 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c(C(F)(F)F)c1 CHEMBL4128665 Kd 8.5 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2CC3CC3C2)c(Cl)c1Cl)C(F)(F)F CHEMBL4646545 Kd 8.5 nM
O=C([C@H]1CC[C@H](c2nn[nH]n2)CC1)N1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(OCc4c(F)cccc4C(F)(F)F)cc3CC[C@@H]12 CHEMBL4644213 EC50 8.5 nM
CN1C(=O)[C@H](F)C[C@H]1C(=O)N1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4762129 EC50 8.5 nM
O=C(CO)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4859011 EC50 8.5 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CCCC1 CHEMBL3598048 IC50 8.6 nM
C[C@@H](O)C(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4866347 EC50 8.6 nM
CCn1c2ccc(CC3CC3)cc2c2cc(C(=O)NCc3ccc(S(=O)(=O)CC)cc3)ccc21 CHEMBL5401542 EC50 8.6 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(CC(C)(C)C(=O)O)nc2CC2CCC2)c(C(F)(F)F)c1)C(F)(F)F CHEMBL4645942 Kd 8.7 nM
O=C(N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12)C1CCS(=O)(=O)CC1 CHEMBL4796103 EC50 8.7 nM
O=S1(=O)CCC(N[C@@H]2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4859021 EC50 8.7 nM
CCCN(Cc1ccccc1)Cc1ccc(NC(=O)Cc2ccc(S(=O)(=O)CC)cc2)cc1Cl CHEMBL5088058 EC50 8.7 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc(CCN3CCCc4ccc(CC(C)C)cc43)cc2)nc1 CHEMBL4851088 EC50 8.9 nM
CCS(=O)(=O)c1ccc(CNC(=O)c2ccc(CCN3CCCc4ccc(OC(C)C)cc43)cc2)nc1 CHEMBL4863518 EC50 8.9 nM
Cn1ccnc1SCC(=O)Nc1sc2c(c1C(=O)NCc1ccccc1)CCCC2 CHEMBL5430108 IC50 8.98 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3cccc(Cl)c3)c(F)c2)CC1 CHEMBL3581541 EC50 9.0 nM
O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C(F)(F)F)n3ccccc23)c(F)c1 CHEMBL3598149 EC50 9.0 nM
CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cc(Cl)ccc3Cl)c(F)c2)CC1 CHEMBL3892943 IC50 9.0 nM
CCS(=O)(=O)c1ccc(C(NC(C)=O)C(=O)Nc2cc(-c3cc(C#N)cc(F)c3OC)cs2)cc1 CHEMBL4168496 IC50 9.0 nM
Cc1ccc(S(=O)(=O)[C@@]23CCN(C(=O)[C@H]4CC[C@H](C(=O)O)CC4)[C@@H]2CCc2cc(C(F)(C(F)(F)F)C(F)(F)F)ccc23)cc1 CHEMBL4462790 EC50 9.0 nM
O=C(O)c1ccc(-c2cn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccnc23)c(F)c1 CHEMBL4538881 IC50 9.0 nM
CC(C)(C)Cc1cc(-c2onc([C@@H](CCC(=O)[O-])CC(=O)Nc3ccc(Cl)cc3Cl)c2C2CC2)no1 CHEMBL4537625 EC50 9.0 nM
C[C@H]1C[C@@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4ccc(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CCS1(=O)=O CHEMBL4643438 EC50 9.0 nM
O=C(O)CC[C@H]1CN(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(-c3ccccc3Cl)ccc2O1 CHEMBL4874524 EC50 9.0 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3nc4ccc(C)cc4n3[C@H](C)c3ccc(C)cc3)cc2)cc1 CHEMBL5289748 IC50 9.0 nM
[2H]C([2H])([2H])N1C(=O)[C@@H](F)C[C@H]1C(=O)N1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4782896 EC50 9.1 nM
CC(C)(O)COC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4860008 EC50 9.1 nM
CC(=O)N1CCN(c2ccc(S(=O)(=O)N(Cc3ccccc3C(F)(F)F)CC(C)C)cc2)CC1 CHEMBL3361049 IC50 9.2 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ncc(-c2cc(NC(C)=O)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598054 IC50 9.2 nM
COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 CHEMBL3957588 Kd 9.2 nM
CCCN(Cc1ccccc1)Cc1ccc(C(=O)NCc2ccc(S(=O)(=O)CC)cc2)cc1 CHEMBL5090127 EC50 9.2 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3)c(Cl)c2)cc1 CHEMBL5427933 XC50 9.2 nM
[2H]C([2H])([2H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(=O)N3CC(O)C3)nn2C(C)C)cc1N1CC2CC2C1 CHEMBL3598065 IC50 9.4 nM
CC(C)(C)c1cc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)cc(C(O)(C(F)(F)F)C(F)(F)F)c1 CHEMBL4126690 IC50 9.4 nM
C[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N2C3CCC2CC3)c(Cl)c1Cl)C(F)(F)F CHEMBL4633497 Kd 9.4 nM
O=C(N1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(OCc4c(F)cccc4C(F)(F)F)cc3CC[C@@H]12)C1(O)CCS(=O)(=O)CC1 CHEMBL4636914 EC50 9.4 nM
CCCN(Cc1ccc(NC(=O)Cc2ccc(S(=O)(=O)CC)cc2)cc1)Cc1ccccc1F CHEMBL5087958 EC50 9.4 nM
Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C(F)(F)F)c(-c3ccccc3)c(C(F)(F)F)c2c1 CHEMBL4073568 Kd 9.5 nM
COc1ccc2c(n1)CCN(C(C)=O)C2C(=O)Nc1ccc2c(c1)CCN2Cc1ccccc1OC CHEMBL4543504 EC50 9.5 nM
CC[C@H](NS(=O)(=O)c1ccc(-c2sc(C(=O)NCC(C)(C)O)nc2C(=O)N(CC)CC)c(C(F)F)c1F)C(F)(F)F CHEMBL4643697 Kd 9.6 nM
O=C(O)[C@H]1CC[C@H](C(=O)N2CC[C@@]3(S(=O)(=O)c4ccc(F)cc4)c4cc(Cl)c(C(F)(C(F)(F)F)C(F)(F)F)cc4CC[C@@H]23)CC1 CHEMBL4776069 EC50 9.6 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCOc4ccc(CC(C)C)cc43)cc2)cc1 CHEMBL4848879 EC50 9.6 nM
C[C@@H]1CCCN1C(=O)c1nc(C(=O)NCC(C)(C)O)sc1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)c(Cl)c1Cl CHEMBL5180983 IC50 9.6 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(CCN3CCCc4ccc(CC(C)C)cc43)cc2)nc1 CHEMBL4865740 EC50 9.7 nM
CCn1c2ccc(CC3CC3)cc2c2cc(C(=O)NCc3ccc(S(=O)(=O)CC)cn3)ccc21 CHEMBL5420330 EC50 9.7 nM
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(C(C)(C)C(=O)Nc3cccc(F)c3)cc2)cc1 CHEMBL4281750 IC50 9.8 nM
CCS(=O)(=O)c1ccc(CNc2nc3cnc(-c4c(OC)ncnc4C4CC4)nc3n([C@@H](C)C(F)(F)F)c2=O)nc1 CHEMBL4749982 IC50 9.9 nM
NS(=O)(=O)CC(=O)N[C@@H]1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3CC[C@@H]12 CHEMBL4878821 EC50 9.9 nM