Cc1nc([C@](C)(O)CO)sc1-c1cnc(N)c(O[C@H](C)c2cc(F)ccc2-n2nccn2)c1 CHEMBL3128069 Ki 0.02 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 0.07 nM
C[C@H]1CNC(=O)c2cnn3ccc(nc23)N[C@H](C)c2cc(F)ccc2O1 CHEMBL4298138 IC50 0.07 nM
C[C@H]1Oc2cc(cnc2N)-c2c(nn(C)c2C#N)CN(C)C(=O)c2ccc(F)cc21 CHEMBL3286830 Ki 0.1 nM
O=C1NC2(CC2)COc2ncc(F)cc2[C@H]2CCCCN2c2ccn3ncc1c3n2 CHEMBL5093999 IC50 0.2 nM
CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1 CHEMBL1983268 IC50 0.2 nM
C[C@@H](Cc1c(F)c(F)cc(F)c1F)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)CN(CCN(C)C)C3=O CHEMBL3671311 IC50 0.205 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687195 IC50 0.23 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4454732 IC50 0.23 nM
CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL1980995 IC50 0.248 nM
COc1cc(Nc2nc(NC3CCOCC3)c(C(C)C)nc2C(N)=O)ccc1N1CCN(C)CC1 CHEMBL3687223 IC50 0.29 nM
COc1cc(Nc2nc(NC3CCOCC3)c(C(C)C)nc2C(N)=O)ccc1N1CCN(C)CC1 CHEMBL4438727 IC50 0.29 nM
C[C@@H](Cc1c(F)c(F)cc(F)c1F)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)CN(C1CCN(C)CC1)C3=O CHEMBL3671309 IC50 0.3 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C(C)C)CC3)c(C)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687210 IC50 0.37 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C(C)C)CC3)c(C)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4528166 IC50 0.37 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 0.3981 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687191 IC50 0.4 nM
Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCNCC1 CHEMBL2403108 Ki 0.4 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4441604 IC50 0.4 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1NC1CCOCC1 CHEMBL3687224 IC50 0.41 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1NC1CCOCC1 CHEMBL4591953 IC50 0.41 nM
COc1cc(N2CCN(CCN(C)C)C2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4470529 IC50 0.43 nM
C[C@@H](Cc1c(F)c(F)cc(F)c1F)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(CCN(C)C)C3=O CHEMBL3671310 IC50 0.436 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 0.49 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C(F)(F)F)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687205 IC50 0.51 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1NC1CCOCC1 CHEMBL3687221 IC50 0.51 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C(F)(F)F)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4465573 IC50 0.51 nM
CC(C)c1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1NC1CCOCC1 CHEMBL4483656 IC50 0.51 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)c(F)c2)nc1NC1CCOCC1 CHEMBL3687222 IC50 0.58 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)c(F)c2)nc1NC1CCOCC1 CHEMBL4461418 IC50 0.58 nM
C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL601719 Ki 0.6 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687202 IC50 0.65 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4466977 IC50 0.65 nM
CC(Cc1cc(F)ccc1F)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(CCN(C)C)C3 CHEMBL3671318 IC50 0.688 nM
COc1cc(NC(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4562805 IC50 0.73 nM
COc1cc(N2CCN(CC(N)=O)C2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4573193 IC50 0.76 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1N[C@H]1CC[C@](C)(O)CC1 CHEMBL3687212 IC50 0.78 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1N[C@H]1CC[C@](C)(O)CC1 CHEMBL4438824 IC50 0.78 nM
COc1cc(N2CCN(CC(=O)N3CCN(C)CC3)C2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4447747 IC50 0.81 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687194 IC50 0.86 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1N[C@H]1CC[C@@](C)(O)CC1 CHEMBL3687207 IC50 0.86 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4465661 IC50 0.86 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1N[C@H]1CC[C@@](C)(O)CC1 CHEMBL4524842 IC50 0.86 nM
COc1cc(N2CCN(CC(=O)N(C)C)C2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4519408 IC50 0.97 nM
COc1cc(NC(=O)N2CCCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4448400 IC50 0.97 nM
c1ccc(CNc2nc(Nc3cc(C4CC4)[nH]n3)c3sccc3n2)cc1 CHEMBL1997924 pKi 1.0 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C(F)(F)F)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL3687200 IC50 1.0 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C(F)(F)F)c2)nc1N[C@H]1CC[C@H](O)CC1 CHEMBL4574005 IC50 1.0 nM
O=C1NC2(CC2)COc2ncc(F)cc2[C@H]2COCCN2c2ccn3ncc1c3n2 CHEMBL5080010 IC50 1.0 nM
COc1cc(-n2cc(CN3CCN(C)CC3)nn2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4174347 IC50 1.1 nM
C[C@@H]1CCc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc(c3n2)C(=O)N1 CHEMBL4297627 IC50 1.15 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCOCC1 CHEMBL3687225 IC50 1.2 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCOCC1 CHEMBL4591308 IC50 1.2 nM
O=C1NC2(CC2)COc2ncc(F)cc2[C@H]2CNCCN2c2ccn3ncc1c3n2 CHEMBL5070835 IC50 1.2 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCOCC1 CHEMBL3687215 IC50 1.3 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCOCC1 CHEMBL4580325 IC50 1.3 nM
CC(Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL1825138 pKi 1.585 nM
Cc1cc(Nc2nc(N[C@H]3CC[C@H](O)CC3)c(Cl)nc2C(N)=O)ccc1N1CCC(N2CCN(C)CC2)CC1 CHEMBL3687217 IC50 1.6 nM
Cc1cc(Nc2nc(N[C@H]3CC[C@H](O)CC3)c(Cl)nc2C(N)=O)ccc1N1CCC(N2CCN(C)CC2)CC1 CHEMBL4580299 IC50 1.6 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2cc(NC[C@H](C)O)nc(-c3cccnc3)n2)c1 CHEMBL560733 IC50 1.7 nM
COc1cc(N2CCN(CC(=O)N3CCC(=O)CC3)C2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4464571 IC50 1.7 nM
COc1cc(NC(=O)N2CCN(CCO)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4468370 IC50 1.7 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(N/N=C/c2ccc(F)cc2)ncc1Cl CHEMBL3921664 IC50 1.8 nM
COc1cc(N2CCC(N(C)C)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1 CHEMBL3397300 IC50 1.9 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1 CHEMBL3545311 IC50 1.9 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1NC1CCOCC1 CHEMBL3687220 IC50 1.9 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(OC)c2)nc1NC1CCOCC1 CHEMBL3301622 IC50 1.9 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2)nc1NC1CCOCC1 CHEMBL4463071 IC50 1.9 nM
CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(OC)c2)nc1NC1CCOCC1 CHEMBL4524472 IC50 1.9 nM
CCN1CCN(C(=O)CS(=O)(=O)c2ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c(OC)c2)CC1 CHEMBL4749215 IC50 1.9 nM
CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1 CHEMBL1970142 pKi 1.995 nM
C=CC(=O)Nc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC)cc1N(C)CCN(C)C CHEMBL4473365 IC50 2.0 nM
COc1ccc(/C=N/Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)cc1 CHEMBL3894726 IC50 2.3 nM
C[C@@H](Oc1cc(-c2ccn(CCN(C)C)c(=O)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL4559485 IC50 2.3 nM
COc1cc(SCc2ccc(CN(C)C)o2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1 CHEMBL4753590 IC50 2.3 nM
Cc1c2c(cc3[nH]c(-c4c(NC(C)Cc5c(F)c(F)cc(F)c5F)cc[nH]c4=O)nc13)C(=O)N(C1CCN(C)CC1)C2 CHEMBL3671320 IC50 2.365 nM
COc1cc2c(cc1Nc1nc(Nc3cccc(F)c3C(N)=O)c3cc[nH]c3n1)N(C(=O)CN(C)C)CC2 CHEMBL461876 pKi 2.512 nM
Cc1cc(Nc2ncc(F)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc1N1CCN(C)CC1 CHEMBL1967878 pKi 2.512 nM
C/C(=N\Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)c1ccc(F)cc1 CHEMBL3922762 IC50 2.7 nM
COc1cc(-n2cc(CN3C[C@@H](C)N[C@@H](C)C3)nn2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4166436 IC50 3.0 nM
Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(OC(F)F)cc5)cc4)csc23)cn1 CHEMBL1988387 pKi 3.162 nM
COc1cc(NC(=O)C2CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4462528 IC50 3.2 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(N/N=C/c2ccc(C(F)(F)F)cc2)ncc1Cl CHEMBL3893810 IC50 3.4 nM
COc1cc(NC(=O)NC2CCC(=O)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4546844 IC50 3.7 nM
COc1cc(OCC2CCCO2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1 CHEMBL4748361 IC50 3.7 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1982466 pKi 3.981 nM
COc1cc(SCc2ccc(CN3CCCC3)o2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1 CHEMBL4741967 IC50 4.2 nM
COc1cc(N2CCCC2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4471142 IC50 4.4 nM
COc1cc(-n2cc(CN3CCC(C)CC3)nn2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4168473 IC50 4.6 nM
COc1cc(NCC2CCCO2)ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1 CHEMBL4787021 IC50 4.6 nM
COc1ccc(/C(C)=N/Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)cc1 CHEMBL3950479 IC50 4.7 nM
COCC1CN(C2CCN(c3cc(OC)c(Nc4ncc(Br)c(Nc5ccc6c(c5P(C)(C)=O)OCCO6)n4)cc3C)CC2)C1 CHEMBL5188373 IC50 4.7 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(N/N=C/c2cccc(C(F)(F)F)c2)ncc1Cl CHEMBL3934594 IC50 5.0 nM
Cc1cc(N2CCOCC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 CHEMBL2005886 pKi 5.012 nM
CNC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCOCC3)cc2OC)ncc1Cl CHEMBL458997 pKi 5.012 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1980297 pKi 5.012 nM
COc1cc(N2CCN(CCCN)C2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4466920 IC50 5.3 nM
COc1cc(N2CCCNC2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2NC(C)=O)n1 CHEMBL4536955 IC50 5.3 nM
CC(C)S(=O)(=O)c1ccccc1Nc1nc(N/N=C/c2ccc(OC(F)(F)F)cc2)ncc1Cl CHEMBL3913728 IC50 5.5 nM
COc1cccc(/C=N/Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c1 CHEMBL3905284 IC50 5.8 nM
Cc1cccc(Nc2nc(NC3CCCCC3N)cnc2C(N)=O)c1 CHEMBL1974328 pKi 6.31 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 pKi 6.31 nM
COc1cc(N2CCNC2=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4465558 IC50 6.8 nM
COc1cc(NC(=O)/C=C/CN2CCN(C)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4787426 IC50 7.1 nM
NS(=O)(=O)c1cccc(Nc2ncc3ccn(Cc4ccccc4)c3n2)c1 CHEMBL1993424 pKi 7.943 nM
COC(C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 CHEMBL1981047 pKi 7.943 nM
COc1cc(-n2cc(CN3CCNCC3)nn2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4166038 IC50 8.0 nM
CCN1CCN(CCS(=O)(=O)c2ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)C(C)C)n3)c(OC)c2)CC1 CHEMBL4750810 IC50 8.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Ki 8.2 nM
COc1cc(-c2nc(CN3CCC(C)CC3)cs2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4159161 IC50 8.5 nM
COc1cc(-c2nc(CN3CCN(C)CC3)cs2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4167072 IC50 9.8 nM
COc1cc(S(=O)(=O)CC(=O)N2CCN(C)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4754109 IC50 10.0 nM
CN(c1ncccc1CNc1nc(Nc2ccc3c(c2)CC(=O)N3)ncc1C(F)(F)F)S(C)(=O)=O CHEMBL1084546 pKi 12.59 nM
C[C@@H](Nc1ccc2[nH]nc(/C=C/c3ccccn3)c2c1)c1cc(F)cc(F)c1 CHEMBL4792981 Kd 13.0 nM
CC(C)Oc1cc(-c2nc(CN3CCN(CCO)CC3)cs2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4160581 IC50 13.4 nM
Cc1cc(O)cc(-c2nn(C)cc2-c2cc(N3CCOCC3)nc(-c3cccnc3)n2)c1 CHEMBL3310332 IC50 13.6 nM
CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)nc2[nH]ccc12 CHEMBL464552 Kd 15.0 nM
CC(C)Oc1cc(-c2nc(CN3CCN(C)CC3)cs2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL4163707 IC50 19.3 nM
O=c1[nH]c2cnc(-n3cnc4ccc(F)cc43)nc2n1C1CCOc2c(F)cccc21 CHEMBL2000393 pKi 19.95 nM
Cc1n[nH]c2c1C(c1ccccc1Cl)C(C#N)=C(N)O2 CHEMBL1970189 pKi 19.95 nM
COc1cc2c(cc1F)C(c1ccccc1Cl)=Nc1c(n[nH]c1C)N2 CHEMBL1980391 pKi 19.95 nM
CCN1CCN(c2ccc(Nc3ncc4scc(-c5cccc(NS(C)(=O)=O)c5)c4n3)cc2)CC1 CHEMBL4846921 IC50 22.0 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2cc(NCCCCO)nc(-c3cccnc3)n2)c1 CHEMBL3397291 IC50 24.0 nM
NS(=O)(=O)c1cccc(Nc2ncc3ccn(-c4ccccc4)c3n2)c1 CHEMBL1988163 pKi 25.12 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C(C)C(=O)N(C)C)c5)cnc(N)c34)cc2)cc1 CHEMBL2001485 pKi 25.12 nM
COc1ccc2c(NC(=O)Nc3cccc(Br)n3)ccnc2c1 CHEMBL1983932 pKi 25.12 nM
Cc1cc(O)cc(-c2c(-c3cc(NCCCCO)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310338 IC50 25.4 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 26.0 nM
Cc1cnc(Nc2cccc(S(N)(=O)=O)c2)nc1Nc1ccc(OCC(N)=O)cc1 CHEMBL1988838 pKi 31.62 nM
CC(=O)NCC(=O)N1C2CCC1c1cc(Nc3ncc(C(F)(F)F)c(NC4CCC4)n3)ccc12 CHEMBL1983111 pKi 31.62 nM
Nc1ncnc2c1c(I)nn2C1CCC(O)CC1 CHEMBL1996791 pKi 31.62 nM
Nc1ncnc2c1c(-c1cccc(O)c1)cn2C1CCCC1 CHEMBL169390 IC50 42.0 nM
COc1cc(C)nc(Nc2cc(N[C@@H]3CS(=O)(=O)CC[C@@H]3N)cnc2C(N)=O)c1 CHEMBL3415599 IC50 43.0 nM
CS(=O)(=O)N(Cc1ccc2[nH]c(=O)c3cccn3c2c1)C1CC1 CHEMBL1978448 pKi 50.12 nM
COc1cc(C)cc(-c2nn(CC#N)cc2-c2cc(NCCCCO)nc(-c3cccnc3)n2)c1 CHEMBL3397286 IC50 56.0 nM
Cc1cc(O)cc(-c2c(-c3cc(N4CC(O)C4)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310337 IC50 56.6 nM
COc1cc(C)cc(-c2nn(C)cc2-c2cc(N3CCOCC3)nc(-c3cccnc3)n2)c1 CHEMBL3310324 IC50 59.1 nM
O=C(O)CN1CCN(c2cc(-c3cnc4ccc(N5CCC[C@@H]5c5cccc(F)c5)nn34)ccn2)CC1 CHEMBL3582441 IC50 60.0 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 63.1 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)c(C)c2)c1 CHEMBL2004311 pKi 63.1 nM
COc1ccc(-c2cc3nccn3c(Nc3ccccc3C(N)=O)n2)cc1OC CHEMBL1998112 pKi 63.1 nM
COc1ccc2c(NC(=O)Nc3cccc(C(F)(F)F)n3)ccnc2c1 CHEMBL1982660 pKi 63.1 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2cccc(O)c2)n1 CHEMBL243088 pKi 63.1 nM
COc1cc(C)cc(-c2nn(C)cc2-c2cc(NCCCCO)nc(-c3cccnc3)n2)c1 CHEMBL3310326 IC50 63.8 nM
COc1cc(C)cc(-c2c(-c3cc(N4CC(O)C4)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310329 IC50 74.2 nM
CCS(=O)(=O)Nc1ccc2c(c1)/C(=C(/Nc1ccc(CN3CCCCC3)cc1)c1ccccc1)C(=O)N2 CHEMBL514409 Kd 77.0 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3cn[nH]c3c2)n1 CHEMBL244378 pKi 79.43 nM
NC(=O)c1ccc(-c2c[nH]c3nccc(Cl)c23)cc1 CHEMBL1982711 pKi 79.43 nM
O=C(O)c1ccccc1Nc1ccnc(Nc2ccc3[nH]ncc3c2)n1 CHEMBL396523 pKi 79.43 nM
CCCCOc1ncnc2[nH]cc(-c3ccccc3)c12 CHEMBL1996817 pKi 79.43 nM
O=C1NN=Cc2c[nH]c3cc(NC(=O)C4CC4c4ccccc4)cc1c23 CHEMBL1969502 pKi 79.43 nM
Cc1cc(O)cc(-c2nn(C)cc2-c2cc(N3CC(O)C3)nc(-c3cccnc3)n2)c1 CHEMBL3310333 IC50 86.5 nM
COc1cc(C)cc(-c2nn(CC#N)cc2-c2cc(NCCCN3CCOCC3)nc(-c3cccnc3)n2)c1 CHEMBL3397288 IC50 88.0 nM
Cc1cc(O)cc(-c2c(-c3cc(N4CCOCC4)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310336 IC50 91.5 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)O)c5)cnc(N)c34)cc2)c1 CHEMBL1989708 pKi 100.0 nM
NC(=O)c1cc(-c2cccc(N)c2)cc2cccnc12 CHEMBL1970314 pKi 100.0 nM
COc1cc(C)cc(-c2c(-c3cc(N4CCOCC4)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310328 IC50 104.0 nM
Cc1cc(O)cc(-c2nn(C)cc2-c2cc(NC[C@H](C)O)nc(-c3cccnc3)n2)c1 CHEMBL3310335 IC50 105.0 nM
COc1ccc(Nc2nccc(-c3cn(C)c4ccccc34)n2)cc1OCCOCCn1ccnc1[N+](=O)[O-] CHEMBL5426036 IC50 106.9 nM
COc1cc(C)cc(-c2nn(C)cc2-c2cc(N3CC(O)C3)nc(-c3cccnc3)n2)c1 CHEMBL3310325 IC50 108.0 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2cc(NCCCO)nc(-c3cccnc3)n2)c1 CHEMBL3397290 IC50 108.0 nM
COc1cc(C)cc(-c2nn(CC#N)cc2-c2cc(NCCCO)nc(-c3cccnc3)n2)c1 CHEMBL3397285 IC50 119.0 nM
NC(=O)c1nnc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc2cc[nH]c12 CHEMBL3416026 Kd 120.0 nM
CN1CCN(c2ccc(Nc3ncc(Cl)c(NC[C@H]4CCCO4)n3)cc2)CC1 CHEMBL3426891 IC50 124.0 nM
COc1cc(N2CCN(C)CC2)ccc1C(=O)Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12 CHEMBL1973961 pKi 125.89 nM
CCN1CCN(c2ccc(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6ccccc6F)c5)nc5ccccn45)n3)cc2)CC1 CHEMBL1981725 pKi 125.89 nM
Cc1nc(N)sc1-c1ccnc(Nc2ccc(N3CCOCC3)cc2)n1 CHEMBL482967 pKi 125.89 nM
Cc1cc(O)cc(-c2nn(C)cc2-c2cc(NCCCCO)nc(-c3cccnc3)n2)c1 CHEMBL3310334 IC50 133.0 nM
COc1cc(C)cc(-c2c(-c3cc(NCCCCO)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310330 IC50 138.0 nM
Cc1cc(O)cc(-c2c(-c3cc(NC[C@H](C)O)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310504 IC50 139.0 nM
COc1cc(C)cc(-c2nn(CC#N)cc2-c2cc(NCCN3CCOCC3)nc(-c3cccnc3)n2)c1 CHEMBL3397287 IC50 148.0 nM
OC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1986943 pKi 158.49 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 158.49 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 CHEMBL572878 pKi 158.49 nM
CNC(=O)COc1ccc(Nc2nc(Nc3ccc(C)c(S(N)(=O)=O)c3)ncc2F)cc1 CHEMBL1978099 pKi 158.49 nM
c1cc2cc(-c3ccc4cn[nH]c4c3)cnc2[nH]1 CHEMBL1976134 pKi 158.49 nM
CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(NC(=O)c5cc6ccccc6n5C)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1972584 pKi 158.49 nM
COc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2OC)=NC3)ccc1C(=O)O CHEMBL483158 pKi 158.49 nM
CC(C)Cc1cc(-c2ccc3[nH]nc(N)c3c2)on1 CHEMBL1966343 pKi 158.49 nM
OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(-c2ccc3cnccc3c2)c1)c1ccccc1 CHEMBL4067871 IC50 168.5 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2cc(NCCCN3CCOCC3)nc(-c3cccnc3)n2)c1 CHEMBL3397293 IC50 183.0 nM
Nc1ncnc2onc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213505 pKi 199.53 nM
Clc1cc(NC2CCCCC2)nc(-c2c[nH]c3ncccc23)n1 CHEMBL1997846 pKi 199.53 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(C=Cc3ccccc3)n2)n[nH]1 CHEMBL1983923 pKi 199.53 nM
NCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL592030 pKi 199.53 nM
Fc1cnc(Nc2ccccc2)nc1Nc1ccccc1 CHEMBL491758 pKi 199.53 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2ccnc(-c3cccnc3)c2)c1 CHEMBL575265 IC50 209.0 nM
OC1CCN(c2cc(-c3cnc4ccc(N5CCC[C@@H]5c5cccc(F)c5)nn34)ccn2)CC1 CHEMBL3582442 IC50 210.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 238.0 nM
COc1cc(C)cc(-c2nn(C)cc2-c2cc(NC[C@H](C)O)nc(-c3cccnc3)n2)c1 CHEMBL3310327 IC50 241.0 nM
S=c1[nH]nc2c3c4c(sc3n3c(=S)[nH]nc3n12)CCC4 CHEMBL1969537 pKi 251.19 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc1)CCN2 CHEMBL411903 pKi 251.19 nM
CN1CCC(c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)C(O)C1 CHEMBL422897 pKi 251.19 nM
CN1CCN(c2cccc(Nc3nccc(-c4c(C(N)=O)nc5ccccn45)n3)c2)CC1 CHEMBL1971245 pKi 251.19 nM
CC(C)OC1=NNC(=O)C1=Cc1c[nH]c2ccccc12 CHEMBL1989029 pKi 251.19 nM
Cc1n[nH]c2ccc(-c3cc(N[C@@H](CO)c4ccccc4)cnc3-c3cc(Cl)ccc3O)cc12 CHEMBL4105329 IC50 272.9 nM
COc1cc(C)cc(-c2c(-c3cc(NC[C@H](C)O)nc(-c4cccnc4)n3)cnn2C)c1 CHEMBL3310331 IC50 283.0 nM
N#Cc1ccc(-c2cnc3ccc(NCc4ccccc4)nn23)cc1 CHEMBL3582427 IC50 300.0 nM
CN1CCN(c2ccc(-c3cnc4c(c3)N(Cc3c(F)ccc(F)c3Cl)CCN4)cn2)CC1 CHEMBL1164265 pKi 316.23 nM
NC(=O)c1ccc(NC2CCCCC2N)nc1Nc1cccc(Cl)c1 CHEMBL1982753 pKi 316.23 nM
O=C1CCCN1Cc1ccc2c(c1)[nH]c(=O)c1cccn12 CHEMBL539474 pKi 316.23 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(C(=O)NCc4cccc(F)c4)cc2NC3=O)ccc1O CHEMBL2000832 pKi 316.23 nM
COc1ccc(CN(C)C)cc1Nc1nccc(-c2c(-c3cccc(NC(=O)c4c(F)cccc4F)c3)nc3sccn23)n1 CHEMBL1997051 pKi 316.23 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4ccccc4C(F)(F)F)cc3)c12 CHEMBL1987910 pKi 316.23 nM
Cc1ncc(-c2ccnc(-c3cccnc3)c2)c(-c2ccc(Cl)cc2Cl)n1 CHEMBL3397299 IC50 330.0 nM
COCCCNc1cc(-c2cnc(C)nc2-c2ccc(Cl)cc2Cl)nc(-c2cccnc2)n1 CHEMBL3397295 IC50 357.0 nM
COc1ccc(CNC(=O)c2cccc(C(C)Oc3ccnc(Nc4cnn(C5CCNCC5)c4)c3)c2)cc1OC CHEMBL4166182 IC50 370.0 nM
O=c1ncn2nc(Sc3ccc(F)cc3F)ccc2c1-c1c(Cl)cccc1Cl CHEMBL119385 pKi 398.11 nM
COc1ccc2c(c1)C(=Cc1c[nH]cn1)C(=O)N2 CHEMBL2002649 pKi 398.11 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1998585 pKi 398.11 nM
Cc1n[nH]c2cnc(-c3cncc(OCC(N)Cc4cccc(C(F)(F)F)c4)c3)cc12 CHEMBL1998159 pKi 398.11 nM
Cc1c[nH]c2nccc(Oc3c(F)cc(Nc4cc(Cl)nc(N)n4)cc3F)c12 CHEMBL1971943 pKi 398.11 nM
CS(=O)(=O)Nc1ccc(-c2ccc3[nH]nc(N)c3c2)cc1 CHEMBL2004892 pKi 398.11 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)c(C(F)(F)F)c2)c1 CHEMBL1971021 pKi 398.11 nM
COc1cc(CNC(=O)c2cccc(C(C)Oc3ccnc(Nc4cnn(C)c4)c3)c2)cc(OC)c1OC CHEMBL4168903 IC50 410.0 nM
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL608533 Kd 430.0 nM
COc1ccc(CNC(=O)c2cccc(C(C)Oc3ccnc(Nc4ncccn4)c3)c2)cc1OC CHEMBL4174101 IC50 440.0 nM
Cc1ccc(CNC(=O)c2cccc(C(C)Oc3ccnc(Nc4cnn(C5CCN(C)CC5)c4)c3)c2)cc1 CHEMBL4173409 IC50 440.0 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2cc(NCCN3CCOCC3)nc(-c3cccnc3)n2)c1 CHEMBL3397292 IC50 478.0 nM
O=C1Nc2ccccc2Nc2nnc(I)cc21 CHEMBL1977346 pKi 501.19 nM
Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F CHEMBL191003 pKi 501.19 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(C(=O)NCCNC(C)=O)cc2NC3=O)ccc1O CHEMBL1975500 pKi 501.19 nM
NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(-c3ccncc3)ccc2c1=O CHEMBL340384 pKi 501.19 nM
COc1cc(N2CCNCC2)ccc1Nc1cc(N2CCC[C@H](C(=O)NCc3ccc(OC(F)(F)F)cc3)C2)ccn1 CHEMBL4523063 IC50 530.0 nM
Cc1ncc(-c2ccnc(-c3cccnc3)c2)c(-c2ccc(F)cc2Cl)n1 CHEMBL3397298 IC50 570.0 nM
COc1ccc(CNC(=O)c2cccc(C(C)Oc3ccnc(Nc4cnn(C5CCN(C)CC5)c4)c3)c2)cc1OC CHEMBL4162738 IC50 570.0 nM
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL1287853 Kd 600.0 nM
Fc1cccc([C@H]2CCCN2c2ccc3ncc(-c4ccccn4)n3n2)c1 CHEMBL3582439 IC50 600.0 nM
CC(=O)Nc1c(C(N)=O)sc2ccc(Cl)c(Cl)c12 CHEMBL1973142 pKi 630.96 nM
CCCS(=O)(=O)Nc1ccc(-c2ccc3[nH]nc(N)c3c2)cc1 CHEMBL1992342 pKi 630.96 nM
CC(O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 CHEMBL2002165 pKi 630.96 nM
Cc1n[nH]c2c1C(c1ccccc1I)C(C#N)=C(N)O2 CHEMBL1979318 pKi 630.96 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(Cl)c4)c3)cc12 CHEMBL1974870 pKi 630.96 nM
Cc1ccc(C(=O)Nc2c(C(N)=O)sc3ccc(Cl)c(Cl)c23)cc1 CHEMBL1965131 pKi 630.96 nM
COc1ccc(C(=O)N2c3ccccc3Sc3c(Cl)cncc32)cc1 CHEMBL1988537 pKi 630.96 nM
Brc1cnc2[nH]cc(-c3ccccc3)c2c1 CHEMBL1992634 pKi 630.96 nM
O=C(NN=Cc1ccc(O)cc1O)Nc1cccc2nsnc12 CHEMBL1999811 pKi 630.96 nM
NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL1998121 pKi 630.96 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12 CHEMBL271381 pKi 630.96 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccc(Cl)c(Cl)c4)c3)cc12 CHEMBL1991063 pKi 630.96 nM
CSc1nn(-c2ccccn2)c(N)c1C(N)=O CHEMBL2004615 pKi 630.96 nM
COc1ccc(CNC(=O)c2cccc(C(C)Oc3ccnc(Nc4cnn(C)c4)c3)c2)cc1OC CHEMBL4176767 IC50 640.0 nM
Cc1cc(O)cc(-c2nn(CC#N)cc2-c2cc(NCC(C)C)nc(-c3cccnc3)n2)c1 CHEMBL3397289 IC50 780.0 nM
CC(=O)c1cccc(-c2cnc3[nH]ccc3c2)c1 CHEMBL2000568 pKi 794.33 nM
OC1CCC(Nc2cc(Cl)nc(-c3c[nH]c4ncccc34)n2)CC1 CHEMBL1991674 pKi 794.33 nM
Oc1cc(O)cc(C=Cc2ccc(O)c(O)c2)c1 CHEMBL1972346 pKi 794.33 nM
c1ccc(COc2ccc(Nc3ncnc4ccccc34)cc2)cc1 CHEMBL1980163 pKi 794.33 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 CHEMBL1970903 pKi 794.33 nM
Nc1ncnc2c1c(I)nn2C1OC(CO)C(O)C1O CHEMBL2001288 pKi 794.33 nM
Cc1n[nH]c2sc(C(=O)NCCc3ccc(Cl)cc3)cc12 CHEMBL1998414 pKi 794.33 nM
NC(=O)c1cccc(-c2cnc3[nH]cc(-c4ccccc4)c3c2)c1 CHEMBL1982957 pKi 794.33 nM
O=C(O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2F)=NC3)cc1 CHEMBL259084 pKi 794.33 nM
O=C(NCc1ccccc1)c1cccc(-c2cnc3[nH]ccc3c2)c1 CHEMBL1972142 pKi 794.33 nM
Cc1nc(COc2ccccc2Cl)sc1-c1ccnc(N)n1 CHEMBL1375640 pKi 794.33 nM
OCCCNc1ncnc2[nH]cc(-c3ccccc3)c12 CHEMBL2000071 pKi 794.33 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 Kd 920.0 nM
COc1cc(C)cc(-c2nn(CC#N)cc2-c2cc(NCC(C)C)nc(-c3cccnc3)n2)c1 CHEMBL3397284 IC50 920.0 nM
CSc1c[nH]c2ncnc(NCCCO)c12 CHEMBL2000114 pKi 1000.0 nM
Brc1ccc2c(c1)-c1[nH]ncc1C2 CHEMBL1995172 pKi 1000.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ccn1 CHEMBL1992306 pKi 1000.0 nM
c1ccc(-c2c[nH]c3ncnc(N4CCCCC4)c23)cc1 CHEMBL1998953 pKi 1000.0 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 1000.0 nM
NC(=O)c1c(OCc2c(F)cc(Br)cc2F)nsc1NC(=O)NCCCCN1CCCC1 CHEMBL253969 pKi 1000.0 nM
Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCC(=O)O CHEMBL2007064 pKi 1000.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(OC(F)(F)F)c4)c3)cc12 CHEMBL1965836 pKi 1000.0 nM
Nc1ncc(C=CC(=O)NCCCn2ccnc2)c2scc(-c3ccc(Br)cc3)c12 CHEMBL1994938 pKi 1000.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN(C)C)cnc(N)c34)cc2)c1 CHEMBL1979883 pKi 1000.0 nM
CN1CCN(C2CCC(n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1997617 pKi 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM