N#C/C(=C\c1cccc(-c2ncnc3[nH]ccc23)c1)C(N)=O CHEMBL5177437 pIC50 0.2512 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 0.426 nM
CCn1c(-c2nonc2N)nc2cncc(CNC3CCNCC3)c21 CHEMBL188434 IC50 0.5 nM
COc1cc(-c2n[nH]c3ccc(/C=C(\C#N)C(=O)NC(C)(C)CO)cc23)cc(OC)c1OC CHEMBL5178687 pIC50 0.631 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 CHEMBL1970903 pKi 0.7943 nM
CCn1c(-c2nonc2N)nc2cncc(OCC3CCNCC3)c21 CHEMBL521823 IC50 1.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccc(Cl)c(Cl)c4)c3)cc12 CHEMBL1991063 pKi 1.259 nM
CCn1c(-c2nonc2N)nc2cncc(CN3CCNCC3)c21 CHEMBL415770 IC50 1.4 nM
Nc1nonc1-c1nc2cnccc2n1C1CC1 CHEMBL185962 IC50 1.5 nM
Nc1nonc1-c1nc2cnccc2n1C1CCCNC1 CHEMBL188806 IC50 2.0 nM
NCc1cccc(-n2c(-c3nonc3N)nc3cnccc32)c1 CHEMBL186317 IC50 2.5 nM
CCn1c(-c2nonc2N)nc2cnccc21 CHEMBL189657 IC50 3.0 nM
Nc1nonc1-c1nc2cnccc2n1C1CCCCC1 CHEMBL189231 IC50 3.0 nM
CCn1c(-c2nonc2N)nc2cncc(CN3CCC(N)CC3)c21 CHEMBL426440 IC50 3.0 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)N3CC[C@@H](N)C3)c21 CHEMBL523695 IC50 3.0 nM
CCn1c(-c2nonc2N)nc2c(Cl)nccc21 CHEMBL187340 IC50 4.0 nM
NCc1ccc(-n2c(-c3nonc3N)nc3cnccc32)cc1 CHEMBL188268 IC50 4.0 nM
O=C1Nc2ccccc2/C1=C/c1c[nH]nc1-c1ccccc1[N+](=O)[O-] CHEMBL2347053 IC50 4.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(Cl)c4)c3)cc12 CHEMBL1974870 pKi 5.012 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN(C)C)cnc(N)c34)cc2)c1 CHEMBL1979883 pKi 5.012 nM
CN(C)c1ccc2c(c1)OC1=CC(N(C)C)C=CC1=C2c1ccc(C(=O)O)cc1C(=O)N[C@H](CCCCN)C(=O)NC(=N)NCCC[C@@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)CCCCCNCCNS(=O)(=O)c1cccc2cnccc12)C(N)=O CHEMBL2023845 Kd 5.3 nM
Nc1nonc1-c1nc2cnccc2n1-c1ccccc1 CHEMBL188433 IC50 6.0 nM
CNCCOc1ccccc1C(C)(C)Nc1nccn(-c2cc(C(=O)NC3CC3)ccc2C)c1=O CHEMBL4792347 pIC50 6.31 nM
CCn1c(-c2nonc2N)nc2cncc(CN3CCCCC3)c21 CHEMBL360219 IC50 7.0 nM
NCC(NC(=O)c1ccc(-c2ccncc2)cc1)c1ccccc1 CHEMBL1990254 pKi 7.943 nM
NC[C@@H](NC(=O)c1ccc(-c2ccncc2)cc1)c1ccccc1 CHEMBL5278787 pIC50 7.943 nM
CCn1c(-c2nonc2N)nc2c(C)nccc21 CHEMBL364413 IC50 8.0 nM
Cn1cc(C2=C(c3cn(CCCSC(=N)N)c4ccccc34)C(=O)NC2=O)c2ccccc21 CHEMBL6291 IC50 8.0 nM
CC(CN)n1c(-c2nonc2N)nc2cnccc21 CHEMBL188620 IC50 9.0 nM
CCn1c(-c2nonc2N)nc2cncc(Br)c21 CHEMBL365832 IC50 9.0 nM
Clc1ccnc(-n2ccc3ncncc32)n1 CHEMBL5190298 pIC50 10.0 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)NC3CCCNC3)c21 CHEMBL493067 IC50 11.0 nM
C=S(=O)(O)c1ccc2c(c1)C(C)(C)C1=[N+]2CCC2OC3CCN4C(=C3C=C12)C(C)(C)c1cc(CC(=O)NCCCC[C@@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)CCCCCNC(=O)[C@@H](CCCNC(=N)N)NC(=O)CCCCCCCNCCNS(=O)(=O)c2cccc3cnccc23)C(N)=O)ccc14 CHEMBL2023841 Kd 12.0 nM
N#Cc1ccc(Cl)nc1-n1ccc2ncncc21 CHEMBL5184056 pIC50 12.59 nM
CCCC(N)n1c(-c2nonc2N)nc2cnccc21 CHEMBL188457 IC50 13.0 nM
NCCCCn1c(-c2nonc2N)nc2cnccc21 CHEMBL363258 IC50 13.0 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)NC3CCNCC3)c21 CHEMBL494662 IC50 13.0 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)N3CC[C@H](N)C3)c21 CHEMBL1956071 IC50 14.0 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)NCCNC)c21 CHEMBL506153 IC50 15.0 nM
Clc1cc(-c2c[nH]c3ncccc23)cc(NCc2ccccc2)n1 CHEMBL1969588 pKi 15.85 nM
O=c1c(NCc2ccc(Cl)c(Cl)c2)c(Nc2ccncc2)c1=O CHEMBL1975900 pKi 15.85 nM
CCn1c(-c2nonc2N)nc2cc(O)ccc21 CHEMBL189094 IC50 17.0 nM
Nc1nonc1-c1nc2cnccc2n1C1CCNCC1 CHEMBL363054 IC50 17.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 17.0 nM
Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3I)cc12 CHEMBL1975128 pKi 19.95 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL1975121 pKi 19.95 nM
Clc1ncc(Cl)c(-c2c[nH]c3ncncc23)n1 CHEMBL5183170 pIC50 19.95 nM
Fc1ncc(Cl)c(-n2ccc3ncccc32)n1 CHEMBL5186781 pIC50 19.95 nM
CCn1c(-c2nccnc2N)nc2cnccc21 CHEMBL189299 IC50 20.0 nM
CCn1c(-c2nonc2N)nc2cncc(OC3CCNCC3)c21 CHEMBL493911 IC50 21.0 nM
NCCCn1c(-c2nonc2N)nc2cnccc21 CHEMBL189773 IC50 22.0 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 25.12 nM
COc1cccc(C(CN)NC(=O)c2ccc(-c3ccncc3)cc2)c1 CHEMBL1976240 pKi 25.12 nM
N=C(N)NCCC[C@@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)CCCCCNCCNS(=O)(=O)c1cccc2cnccc12)C(N)=O CHEMBL2023714 Kd 26.0 nM
CCS(=O)(=O)Nc1ccc2c(c1)/C(=C(/Nc1ccc(CN3CCCCC3)cc1)c1ccccc1)C(=O)N2 CHEMBL514409 Kd 31.0 nM
CCN(CC)CC#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2001257 pKi 31.62 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCCC5)cnc(N)c34)cc2)c1 CHEMBL1973211 pKi 31.62 nM
NC(COc1cncc(-c2ccc3c(c2)CC(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL1967302 pKi 31.62 nM
Clc1ncc(Cl)c(-n2ccc3ncncc32)n1 CHEMBL5191167 pIC50 31.62 nM
Clc1ncc(Br)c(-n2ccc3ncncc32)n1 CHEMBL5178708 pIC50 31.62 nM
CCn1c(-c2nonc2N)nc2cc(F)ccc21 CHEMBL187339 IC50 38.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CC(C)(C)N)cnc(N)c34)cc2)c1 CHEMBL1979577 pKi 39.81 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cc(C(=O)O)ccc4F)cc3)c12 CHEMBL1993722 pKi 39.81 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 42.0 nM
CCc1ccccc1C(=O)Nc1n[nH]c2c(C)c(F)c(C3C(C#N)=C(C)N(C)C(C)=C3C#N)cc12 CHEMBL4580220 IC50 43.0 nM
CCn1c(-c2nonc2N)nc2cncc(C(=O)N3CCNCC3)c21 CHEMBL493066 IC50 47.0 nM
CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc21 CHEMBL220241 IC50 49.0 nM
O=C(NCc1ccc(Br)cc1)Nc1ccc2[nH]ncc2c1 CHEMBL1970709 pKi 50.12 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN)cnc(N)c34)cc2)c1 CHEMBL1965988 pKi 50.12 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(OC(F)(F)F)c4)c3)cc12 CHEMBL1965836 pKi 50.12 nM
CCn1c(-c2c(C)n[nH]c2N)nc2cnccc21 CHEMBL361678 IC50 55.0 nM
CCn1c(-c2c[nH]nc2N)nc2cnccc21 CHEMBL5282422 IC50 55.0 nM
Clc1ncc(Cl)c(-n2ccc3ncccc32)n1 CHEMBL5187801 pIC50 63.1 nM
Cc1ccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)cc1C CHEMBL2000335 pKi 79.43 nM
CCCC(=O)Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccccc3)cc12 CHEMBL2005936 pKi 79.43 nM
CCC(N)(C#Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12)CC CHEMBL1983025 pKi 79.43 nM
Cc1n[nH]c2cnc(-c3cncc(OCC(N)Cc4cccc(C(F)(F)F)c4)c3)cc12 CHEMBL1998159 pKi 79.43 nM
COc1ccc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)cc1Cl CHEMBL272453 pKi 79.43 nM
CC(N)COc1cnc(Cl)c(C=Cc2ccncc2)c1 CHEMBL1993548 pKi 79.43 nM
COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1 CHEMBL1984162 pKi 79.43 nM
Clc1ccnc(-n2ccc3ncccc32)n1 CHEMBL5183977 pIC50 79.43 nM
CS(=O)(=O)Nc1cccc(CC(=O)Nc2nc(-c3c[nH]c4ncccc34)cs2)c1 CHEMBL4249925 Ki 94.0 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 100.0 nM
COCCN(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1 CHEMBL1986970 pKi 100.0 nM
CC(NC(=O)c1ccc(-c2ccncc2)cc1)c1ccccc1 CHEMBL1999428 pKi 100.0 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccccc4)c3)cc12 CHEMBL2002726 pKi 100.0 nM
Clc1ncc(Cl)c(-c2c[nH]c3ncccc23)n1 CHEMBL5191771 pIC50 100.0 nM
CCn1c(-c2cccnc2N)nc2cnccc21 CHEMBL191104 IC50 107.0 nM
O=S(=O)(NCCNC/C=C/c1ccc(Br)cc1)c1cccc2cnccc12 CHEMBL104264 IC50 120.0 nM
Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 CHEMBL1988173 pKi 125.89 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCNS(C)(=O)=O)cnc(N)c34)cc2)c1 CHEMBL1994321 pKi 125.89 nM
NCCC(C(=O)Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL1998121 pKi 125.89 nM
O=C(NC(CO)c1ccccc1)c1ccc(-c2ccncc2)cc1 CHEMBL1974288 pKi 125.89 nM
Cn1c(-c2nonc2N)nc2cnccc21 CHEMBL188048 IC50 126.0 nM
CCn1c(-c2nonc2N)nc2ccccc21 CHEMBL365286 IC50 140.0 nM
N#CC[C@H](C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL1789941 Kd 140.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 150.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 150.0 nM
NC(COc1cncc(C=Cc2ccncc2)c1)Cc1c[nH]c2ccccc12 CHEMBL1974935 pKi 158.49 nM
CC(C)N(C)C(=O)c1c(-c2ccc3[nH]ncc3c2)nnn1Cc1ccccc1 CHEMBL1969561 pKi 158.49 nM
O=C(NC(CO)c1cc(Cl)cc(Cl)c1)c1ccc(-c2ccncc2)cc1 CHEMBL2003341 pKi 158.49 nM
Cc1c(-c2ccc3[nH]nc(N)c3c2)nnn1Cc1ccccc1 CHEMBL1989646 pKi 158.49 nM
N#Cc1ccc(-n2ccc3ncncc32)nc1Cl CHEMBL5198790 pIC50 158.49 nM
CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21 CHEMBL494089 Kd 160.0 nM
CCn1c(-c2nonc2N)nc2c(-c3ccoc3)ncc(OCCCN)c21 CHEMBL445180 IC50 162.0 nM
CCOc1nccc2c1nc(-c1nonc1N)n2CC CHEMBL188240 IC50 174.0 nM
Cc1cc(NC(=O)Cc2ccc(-c3cccc4[nH]nc(N)c34)cc2)ccc1F CHEMBL1984363 pKi 199.53 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(C#CCN5CCOCC5)cnc(N)c34)cc2)c1 CHEMBL1982465 pKi 199.53 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3C)cc2)c1 CHEMBL1970217 pKi 199.53 nM
COc1ccc(C(=O)N2c3ccccc3Sc3c(Cl)cncc32)cc1 CHEMBL1988537 pKi 199.53 nM
CNC(=O)c1cnc(N)c2c(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)csc12 CHEMBL2005631 pKi 199.53 nM
NC(=O)c1cn(-c2ccc(O)cc2Cl)c2cc(-c3ccncc3)ccc2c1=O CHEMBL340384 pKi 199.53 nM
FC(F)(F)c1cnc(-n2ccc3ncccc32)nc1Cl CHEMBL5190450 pIC50 199.53 nM
Clc1cnc(Br)nc1-n1ccc2ncccc21 CHEMBL5208671 pIC50 199.53 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL502835 Kd 200.0 nM
CCn1c(-c2nonc2N)nc2c(OC)nccc21 CHEMBL363990 IC50 209.0 nM
CCc1nccc2c1nc(-c1nonc1N)n2CC CHEMBL365072 IC50 229.0 nM
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL608533 Kd 240.0 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 249.0 nM
NC(Cc1c[nH]c2ccccc12)C(=O)Nc1cncc(C=Cc2ccncc2)c1 CHEMBL1983945 pKi 251.19 nM
Cc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)n[nH]c12 CHEMBL1973937 pKi 251.19 nM
O=C(NC(CO)c1ccccc1)N1CC=C(c2c[nH]c3ncccc23)CC1 CHEMBL1964937 pKi 251.19 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)c1 CHEMBL1967116 pKi 251.19 nM
COc1cc(-c2ccc3c(c2)Nc2ccc(C(=O)NCc4cccc(F)c4)cc2NC3=O)ccc1O CHEMBL2000832 pKi 251.19 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ccnc(N)c34)cc2)c1 CHEMBL394619 pKi 251.19 nM
COc1ccc(-c2ccc(NC(=O)Nc3ccc(F)c(C)c3)cc2)c2c(N)noc12 CHEMBL1979093 pKi 251.19 nM
COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cc1OC CHEMBL514499 pKi 251.19 nM
CCn1c(-c2nonc2N)nc2ccc(O)cc21 CHEMBL365902 IC50 258.0 nM
CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 CHEMBL513909 Kd 270.0 nM
CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1N[C@H]1CC[C@H](CN(C)C)CC1 CHEMBL3688339 Kd apparent 298.0 nM
O=C(NCc1ccccc1)c1ccc(-c2ccncc2)cc1 CHEMBL1977135 pKi 316.23 nM
Cc1cccc(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL220057 pKi 316.23 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12 CHEMBL271381 pKi 316.23 nM
O=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cccc(F)c1 CHEMBL2003638 pKi 316.23 nM
CN(C)c1cccc2c(S(=O)(=O)N(CCN)c3cncc(-c4ccc5cnccc5c4)c3)cccc12 CHEMBL1967544 pKi 316.23 nM
CNS(=O)(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)ncc1Cl CHEMBL1993661 pKi 316.23 nM
Cc1cnc(-n2ccc3ncccc32)nc1Cl CHEMBL5204081 pIC50 316.23 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 345.0 nM
Cn1cc(C2=C(c3cn(C4CCN(Cc5ccccn5)CC4)c4ccccc34)C(=O)NC2=O)c2ccccc21 CHEMBL300138 Kd 370.0 nM
CCOc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 CHEMBL1974254 pKi 398.11 nM
Cc1cc(O)ccc1-n1cc(C(=O)NN)c(=O)c2ccc(-c3ccncc3)cc21 CHEMBL2000894 pKi 398.11 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c1C CHEMBL1990885 pKi 398.11 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL262433 pKi 398.11 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1 CHEMBL196363 pKi 398.11 nM
Cc1cc(O)ccc1-n1cc(C(N)=O)c(=O)c2ccc(-c3ccncc3)cc21 CHEMBL340921 pKi 501.19 nM
COc1cccc(C(C)NC(=O)c2ccc(-c3ccncc3)c(F)c2)c1 CHEMBL2004934 pKi 501.19 nM
Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccccc3)cc12 CHEMBL1972158 pKi 501.19 nM
NC(=O)c1sc2c(Br)ccc(Cl)c2c1N CHEMBL1998611 pKi 501.19 nM
CC(=O)N1CCN(C2CCC(n3nc(-c4ccc(NC(=O)c5cc6ccccc6n5C)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL1972584 pKi 501.19 nM
CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 CHEMBL2004716 pKi 501.19 nM
S=c1[nH]nc2c3c4c(sc3n3c(=S)[nH]nc3n12)CCC4 CHEMBL1969537 pKi 501.19 nM
O=C(NC(CO)Cc1ccccc1)c1ccc(-c2ccncc2)cc1F CHEMBL1969755 pKi 501.19 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c12 CHEMBL1976220 pKi 501.19 nM
CN(C)c1nc2ccc1CCCn1cc(c3ccccc31)C1=C(C(=O)NC1=O)c1cn(c3ccccc13)CC2 CHEMBL1162963 IC50 510.0 nM
CN(C)CCCn1c(-c2nonc2N)nc2cnccc21 CHEMBL191105 IC50 617.0 nM
N#CC1=C(N)n2c(sc(=Cc3ccco3)c2=O)=C(C(N)=O)C1c1ccco1 CHEMBL1989805 pKi 630.96 nM
Cc1nc2ccc(NS(=O)(=O)c3ccc(N)cc3)cc2nc1C CHEMBL2006263 pKi 630.96 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL223360 pKi 630.96 nM
Nc1ncnc2scc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL1998585 pKi 630.96 nM
CC(N)C1CCC(C(=O)Nc2ccnc3[nH]ccc23)CC1 CHEMBL2002992 pKi 630.96 nM
Nc1noc2cccc(-c3cccc(O)c3)c12 CHEMBL1970340 pKi 630.96 nM
O=c1[nH]c2cnc(-n3cnc4ccc(F)cc43)nc2n1C1CCOc2c(F)cccc21 CHEMBL2000393 pKi 630.96 nM
NCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL592030 pKi 630.96 nM
CC(N)C1CCC(C(=O)Nc2ccncc2)CC1 CHEMBL1994526 pKi 630.96 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL231209 pKi 630.96 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 Kd 680.0 nM
c1nc(N2CCC3(CCCNC3)CC2)c2nc[nH]c2n1 CHEMBL2420911 IC50 700.0 nM
O=c1[nH]cnc2c1sc1c(Cl)ccc(Cl)c12 CHEMBL583144 Ki 728.5 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 730.0 nM
O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)Nc2ccccn2)cc1 CHEMBL1973540 pKi 794.33 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CC(C)O)c5)cnc(N)c34)cc2)c1 CHEMBL1989708 pKi 794.33 nM
Cc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL1970074 pKi 794.33 nM
CCn1c(-c2nonc2N)nc2c(-c3ccccc3)nccc21 CHEMBL186343 IC50 813.0 nM
CCn1c(-c2nonc2N)nc2cc(CO)ccc21 CHEMBL185731 IC50 974.0 nM
O=C(Cc1cccc(OCCCC2CCNCC2)c1)Nc1nc(-c2c[nH]c3ncccc23)cs1 CHEMBL4245242 Ki 990.0 nM
CCn1c(-c2nonc2N)nc2c(-c3ccccc3)ncc(OCCCN)c21 CHEMBL493250 IC50 1000.0 nM
Cc1cccc(Nc2nc(NC3CCCCC3N)cnc2C(N)=O)c1 CHEMBL1974328 pKi 1000.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3cc(F)cc(F)c3)cc2)c2c(N)noc12 CHEMBL1969190 pKi 1000.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4c3c(N)nn4C)cc2)c1 CHEMBL402846 pKi 1000.0 nM
Nc1ncnc(Nc2cc(CNC(=O)C(F)(F)F)c(O)c(-c3ccc(Cl)cc3)c2)n1 CHEMBL2001239 pKi 1000.0 nM
Nc1nccc2scc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)c12 CHEMBL394790 pKi 1000.0 nM
COc1cc(-c2ccc3c(c2)Nc2ccc([N+](=O)[O-])cc2NC3=O)ccc1O CHEMBL1995740 pKi 1000.0 nM
O=C1NCCc2[nH]c(-c3ccncc3)cc21 CHEMBL225519 pKi 1000.0 nM
CC(C)Nc1c(-c2ccc3[nH]ncc3c2)nc2ncccn12 CHEMBL1682553 pKi 1000.0 nM
OCCCNc1ncnc2[nH]cc(-c3ccccc3)c12 CHEMBL2000071 pKi 1000.0 nM
Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 CHEMBL1980297 pKi 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM