CCCCCCCCc1ccc(CCC(N)(CO)COP(=O)(O)O)cc1 CHEMBL114606 EC50 0.005 nM
CCCCCCCCc1ccc(CC[C@](N)(CO)COP(=O)(O)O)cc1 CHEMBL366208 EC50 0.006 nM
CCCCCC[C@@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL3806205 EC50 0.006 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)O)cn(C)c34)no2)cc1Cl CHEMBL2018323 pEC50 0.00631 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCC(=O)O)no2)cc1C#N CHEMBL3960697 pEC50 0.007943 nM
COc1ccccc1CC[C@@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL4637401 EC50 0.008 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3ccn4CCC(=O)O)no2)cc1Cl CHEMBL2032300 pEC50 0.01 nM
CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CCOC2CC(=O)O)cc1C#N CHEMBL3403631 IC50 0.01 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1Cl CHEMBL2018176 pEC50 0.01259 nM
CCc1c(CCNCC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059683 pEC50 0.01585 nM
COCCCCC[C@@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL4752394 IC50 0.016 nM
CCCCCCCCc1ccc2c(c1)CC[C@H]([C@@](C)(N)COP(=O)(O)O)C2 CHEMBL1093686 EC50 0.018 nM
CCc1c(CCN(C)CC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059684 pEC50 0.01995 nM
CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CC[C@@H]2CC(=O)O)cc1C(F)(F)F CHEMBL3359523 EC50 0.021 nM
CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CC[C@@H]2CC(=O)O)cc1C#N CHEMBL3359522 EC50 0.025 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3c(Cl)cn4CCC(=O)O)no2)cc1Cl CHEMBL2032301 pEC50 0.02512 nM
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O CHEMBL225155 EC50 0.027 nM
CCCc1ccc(COc2ccc3c(c2)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)c1 CHEMBL4093489 EC50 0.027 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C(F)(F)F)c(C#N)c2)n1 CHEMBL378436 EC50 0.03 nM
O=C(O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3403619 EC50 0.03 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(N)=O)c[nH]c34)no2)cc1Cl CHEMBL2018320 pEC50 0.03162 nM
O=C(O)CNCCCc1ccc2oc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1 CHEMBL2032428 pEC50 0.03162 nM
O=C(O)CCNCCc1ccc2oc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1 CHEMBL2032430 pEC50 0.03162 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2-c2onc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL3959509 EC50 0.032 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2cccc3c2ccn3CCC(=O)O)s1 CHEMBL2011746 pEC50 0.03981 nM
CNC(=O)CCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12 CHEMBL2018321 pEC50 0.03981 nM
O=C(O)C[C@H]1CCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358920 EC50 0.04 nM
CC(C)Cc1ccc(COc2ccc3[nH]c4c(c3c2)CCNC4CC(=O)O)cc1C(F)(F)F CHEMBL3400910 EC50 0.04 nM
CC(C)Oc1ccc(COc2ccc3[nH]c4c(c3c2)CCNC4CC(=O)O)cc1C#N CHEMBL3400909 EC50 0.04 nM
CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CCOC2CC(=O)O)cc1C(F)(F)F CHEMBL3403630 EC50 0.04 nM
O=C(O)CC1OCCn2c1c(Cl)c1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12 CHEMBL3403632 EC50 0.04 nM
CCOCCC[C@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL4786296 IC50 0.04 nM
O=C(O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12 CHEMBL3358955 EC50 0.041 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCN)no2)cc1C#N CHEMBL3926787 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC[C@@H](O)CO)no2)cc1C#N CHEMBL3924073 EC50 0.05 nM
COC(=O)CCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3896496 EC50 0.05 nM
COC(=O)C1CN(C2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)C1 CHEMBL3984513 EC50 0.05 nM
CC(=O)OCCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3944842 EC50 0.05 nM
COCC(=O)NC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3926299 EC50 0.05 nM
CCOCC(=O)NC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3954097 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC[C@H](O)CO)no2)cc1C#N CHEMBL3916821 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC[C@H](C)O)no2)cc1C#N CHEMBL3970830 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCS(C)(=O)=O)no2)cc1C#N CHEMBL3979740 EC50 0.05 nM
CNS(=O)(=O)CCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3939008 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CCNCC3)no2)cc1C#N CHEMBL3940245 EC50 0.05 nM
CNC(=O)CN[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3895822 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N[C@@H](C)CO)no2)cc1C#N CHEMBL3918031 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N[C@H](C)CO)no2)cc1C#N CHEMBL3975029 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N[C@H](C)CO)no2)cc1C#N CHEMBL3972549 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CCOCC3)no2)cc1C#N CHEMBL3930528 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CCC(O)CC3)no2)cc1C#N CHEMBL3907353 EC50 0.05 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4O)no2)cc1C(F)(F)F CHEMBL3969165 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4O)no2)cc1C(F)(F)F CHEMBL3915065 EC50 0.05 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4O)no2)cc1C#N CHEMBL3922629 EC50 0.05 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@H]4O)no2)cc1C#N CHEMBL3919920 EC50 0.05 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4O)no2)cc1OCC CHEMBL3960138 EC50 0.05 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@H]4O)no2)cc1OCC CHEMBL3957449 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CCN(CCO)CC3)no2)cc1C#N CHEMBL3907543 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N(CO)CO)no2)cc1C#N CHEMBL3924318 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)CN)no2)cc1C#N CHEMBL3894084 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)CN(C)C)no2)cc1C#N CHEMBL3920863 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(C)(=O)=O)no2)cc1C#N CHEMBL3952253 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)O)no2)cc1C#N CHEMBL3945226 EC50 0.05 nM
CNCCS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3987097 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN(C)C)no2)cc1C#N CHEMBL3947411 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N3CC(O)C3)no2)cc1C#N CHEMBL3964002 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N3CC(O)C3)no2)cc1C#N CHEMBL3899733 EC50 0.05 nM
COCCN[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3918503 EC50 0.05 nM
CN[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3897106 EC50 0.05 nM
CCN[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3979815 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N(C)C(=O)CO)no2)cc1C#N CHEMBL3943755 EC50 0.05 nM
CCN(CCO)[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3957713 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N(CCO)CCO)no2)cc1C#N CHEMBL3895901 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N(C)C)no2)cc1C#N CHEMBL3905765 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCCF)no2)cc1C#N CHEMBL3891354 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCCS(C)(=O)=O)no2)cc1C#N CHEMBL3934482 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCCS(C)(=O)=O)no2)cc1C#N CHEMBL3931785 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CCC3)no2)cc1C#N CHEMBL3906427 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CCCC3)no2)cc1C#N CHEMBL3941756 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CC[C@@H](O)C3)no2)cc1C#N CHEMBL3927322 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CC[C@H](O)C3)no2)cc1C#N CHEMBL3930042 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)NCCO)no2)cc1C#N CHEMBL3967098 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)CN(C)C)no2)cc1C#N CHEMBL3969712 EC50 0.05 nM
CC(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3926586 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCC(F)F)no2)cc1C#N CHEMBL3960551 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCCF)no2)cc1C#N CHEMBL3947288 EC50 0.05 nM
CN[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3965441 EC50 0.05 nM
CCCN[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3902406 EC50 0.05 nM
COC(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3918159 EC50 0.05 nM
COC(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3920889 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)OCCO)no2)cc1C#N CHEMBL3924832 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N3CCOC3=O)no2)cc1C#N CHEMBL3934530 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N3CCOC3=O)no2)cc1C#N CHEMBL3919810 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCc3cncs3)no2)cc1C#N CHEMBL3967100 EC50 0.05 nM
CCOCCS(=O)(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3987033 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)C3CC3)no2)cc1C#N CHEMBL3978076 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)C3CC3)no2)cc1C#N CHEMBL3963066 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCC3)no2)cc1C#N CHEMBL3964817 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CC[C@@H](O)C3)no2)cc1C#N CHEMBL3949785 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCNCCO)no2)cc1C#N CHEMBL3918328 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CC(O)C3)no2)cc1C#N CHEMBL3968024 EC50 0.05 nM
COC(=O)CCS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3971646 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCO)no2)cc1C#N CHEMBL3894716 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)N3CC(O)C3)no2)cc1C#N CHEMBL3954350 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)N3CCOCC3)no2)cc1C#N CHEMBL3912931 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)N3CCC(O)CC3)no2)cc1C#N CHEMBL3970705 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CC(=O)N(C)C)no2)cc1C#N CHEMBL3976048 EC50 0.05 nM
CNC(=O)CS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3985742 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N3CC(C(=O)O)C3)no2)cc1C#N CHEMBL3937763 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N3CC(C(=O)N(C)C)C3)no2)cc1C#N CHEMBL3940511 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N3CC(C(=O)N(C)C)C3)no2)cc1C#N CHEMBL3905058 EC50 0.05 nM
CNC(=O)C1CN([C@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)C1 CHEMBL3947465 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N(C)CC(=O)O)no2)cc1C#N CHEMBL3942853 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N(C)CCO)no2)cc1C#N CHEMBL3955035 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCOCC3)no2)cc1C#N CHEMBL3902939 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCOCC3)no2)cc1C#N CHEMBL3893180 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCNCC3)no2)cc1C#N CHEMBL3938278 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC[C@H](O)C3)no2)cc1C#N CHEMBL3977376 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC(CO)CC3)no2)cc1C#N CHEMBL3899152 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC[C@@H](O)C3)no2)cc1C#N CHEMBL3958210 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC[C@@H](N)C3)no2)cc1C#N CHEMBL3910977 EC50 0.05 nM
COC(=O)CC1CCN(C(=O)N[C@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)CC1 CHEMBL3935065 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)OCCO)no2)cc1C#N CHEMBL3973804 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC(CC(=O)O)CC3)no2)cc1C#N CHEMBL3934309 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC[C@@H](O)C3)no2)cc1C#N CHEMBL3931604 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC[C@H](O)C3)no2)cc1C#N CHEMBL3957491 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC[C@@H](O)C3)no2)cc1C#N CHEMBL3954873 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC[C@H](O)C3)no2)cc1C#N CHEMBL3919959 EC50 0.05 nM
COC(=O)C1CCN(C(=O)N[C@@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)CC1 CHEMBL3936105 EC50 0.05 nM
COC(=O)C1CCN(C(=O)N[C@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)CC1 CHEMBL3899952 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCC(C(=O)O)CC3)no2)cc1C#N CHEMBL3964055 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC(C(=O)O)CC3)no2)cc1C#N CHEMBL3938039 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC(O)CC3)no2)cc1C#N CHEMBL3977164 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=N)N)no2)cc1C#N CHEMBL3965400 EC50 0.05 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCCCC(=O)O)c[nH]c34)no2)cc1Cl CHEMBL2018319 pEC50 0.05012 nM
CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)cc1C(F)(F)F CHEMBL3359519 EC50 0.067 nM
CC[C@H](C)Oc1ccc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)cc1C#N CHEMBL378054 EC50 0.07 nM
CCCc1ccc(COc2ccc3c(c2C)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)c1 CHEMBL4095920 EC50 0.072 nM
O=C(O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358912 EC50 0.073 nM
CCCCCCCCc1ccc2c(c1)CC[C@@H](C(N)(CO)COP(=O)(O)O)C2 CHEMBL1091103 EC50 0.077 nM
O=C(O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C4CCCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358911 EC50 0.077 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCc5nnn[nH]5)c[nH]c34)no2)cc1Cl CHEMBL2018322 pEC50 0.07943 nM
O=C(O)CCN1CCC(c2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032434 pEC50 0.07943 nM
CCCCCCCOc1ccc(CCC(N)(CO)CO)cc1C(F)(F)F CHEMBL3707375 pEC50 0.07943 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL208924 EC50 0.08 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL211505 EC50 0.08 nM
N#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)c1 CHEMBL2048293 EC50 0.08 nM
N#Cc1cc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)ccc1C1CCCCC1 CHEMBL3358910 EC50 0.087 nM
CCCCCCCCc1ccc2c(c1)CC[C@@H]([C@@](C)(N)COP(=O)(O)O)C2 CHEMBL1089004 EC50 0.088 nM
O=C(O)C[C@@H]1CCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358919 EC50 0.09 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCC(=O)N(C)C)no2)cc1C#N CHEMBL3922998 EC50 0.09 nM
COCCS(=O)(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3933952 EC50 0.09 nM
CCCCCCCCc1ccc(CC[C@@H](N)C[C@@H](O)P(=O)(O)O)cc1 CHEMBL115554 IC50 0.1 nM
CCCCCCCCc1ccc(CC[C@@H](N)C[C@H](O)P(=O)(O)O)cc1 CHEMBL115713 IC50 0.1 nM
CCCCCCCCCc1ccc(C2CCC(CCP(=O)(O)O)N2)cc1 CHEMBL184879 IC50 0.1 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2cnc(OC(C)C(F)(F)F)c(Cl)c2)n1 CHEMBL209484 EC50 0.1 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C(F)(F)F)C(F)(F)F)c(C#N)c2)n1 CHEMBL210942 EC50 0.1 nM
O=C(O)C1CN(CCCc2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)C1 CHEMBL2032441 pEC50 0.1 nM
CCc1c(CCN2CCC(C(=O)O)CC2)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059687 pEC50 0.1 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C2CCC2)n1 CHEMBL3126588 EC50 0.1 nM
CCc1cc(-c2noc(-c3cc(C)nc(C4CCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126584 EC50 0.1 nM
CCc1cc(-c2noc(-c3cc(C)nc(CC(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126436 EC50 0.1 nM
CCc1cc(-c2noc(-c3ccnc(C4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126433 EC50 0.1 nM
CCc1cc(-c2noc(-c3ccnc(C(CC)CC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126607 EC50 0.1 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cnc1CC(C)C CHEMBL3126623 EC50 0.1 nM
CCc1cc(-c2noc(-c3cnc(C4CCCC4)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126622 EC50 0.1 nM
CCc1cc(-c2noc(-c3cnc(C(C)C)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126620 EC50 0.1 nM
CC(C)Oc1ccc(-c2nc(-c3cc(F)c(OC[C@H](N)CO)cc3Cl)no2)cc1C#N CHEMBL3753584 EC50 0.1 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCO)no2)cc1C#N CHEMBL3895230 EC50 0.1 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC(O)C3)no2)cc1C#N CHEMBL3910269 EC50 0.1 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC(O)C3)no2)cc1C#N CHEMBL3893172 EC50 0.1 nM
CC[C@@H](Nc1cc(CNCCC(=O)O)c(Cl)cn1)c1ccc(Cl)c(C)c1 CHEMBL3671065 IC50 0.1 nM
Cc1cc([C@H](Nc2ccc(C)c(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671077 IC50 0.1 nM
Cc1cc([C@H](Nc2ccc(F)c(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671078 IC50 0.1 nM
COCCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cnn1C1CCCCC1 CHEMBL3701824 Ki 0.1 nM
COC(=O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3953201 EC50 0.102 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OCC(F)(F)F)c(C#N)c2)n1 CHEMBL379380 EC50 0.11 nM
O=C(O)C[C@H]1CCCN(CC(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4474984 IC50 0.11 nM
Cc1cc(C(C)CC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL391869 EC50 0.12 nM
Cc1cc(-c2noc(CCC3(c4ccc(F)cc4)CCCCC3)n2)cc(C)c1OC[C@@H](O)CO CHEMBL3671362 IC50 0.12 nM
CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)cc1C#N CHEMBL3359520 EC50 0.13 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N(C)C)no2)cc1C#N CHEMBL3921214 EC50 0.13 nM
CCCc1c(-c2nc(-c3ccc(C(O)CNCCC(=O)O)cc3)no2)noc1-c1ccccc1 CHEMBL4569675 IC50 0.13 nM
CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)cc1F CHEMBL515921 IC50 0.14 nM
CCCCCCCCc1ccc(CC[C@@](N)(CO)COP(=O)(O)O)cc1 CHEMBL190006 EC50 0.14 nM
CCCCCCCCOc1ccc(-c2cc([C@@](C)(N)COP(=O)(O)O)on2)cc1C(F)(F)F CHEMBL3102907 Activity 0.14 nM
O=C(O)CC1OCCn2c1cc1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12 CHEMBL3403626 EC50 0.14 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 CHEMBL206940 EC50 0.15 nM
CN1CCn2c(c(Cl)c3cc(OCc4ccc(C5CCCC5)c(C(F)(F)F)c4)ccc32)C1CC(=O)O CHEMBL3403636 EC50 0.15 nM
O=C(O)C1CCN(CCc2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032436 pEC50 0.1585 nM
CCc1c(CCN2CCC(C(=O)O)CC2)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 CHEMBL2057282 pEC50 0.1585 nM
CCCCCCCCc1ccc(CCC(N)CC(O)P(=O)(O)O)cc1 CHEMBL113344 IC50 0.16 nM
CCCCCCCCCc1ccc(CN[C@H]2CCC[C@H](P(=O)(O)O)C2)cc1 CHEMBL181597 IC50 0.16 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(CC(C)C)c(C#N)c2)s1 CHEMBL208718 EC50 0.16 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCCO)no2)cc1C#N CHEMBL3951270 EC50 0.16 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCCO)no2)cc1C#N CHEMBL3707247 EC50 0.16 nM
CCOc1ccc(-c2nc(-c3cccc4c3CCC4O)no2)cc1OCC CHEMBL3919445 EC50 0.16 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N)no2)cc1C#N CHEMBL3902160 EC50 0.17 nM
Cc1cc(CCC(=O)O)ccc1-c1ncc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL211046 EC50 0.18 nM
CCCCCCCCOc1ccc(-c2cnc([C@@](C)(N)COP(=O)(O)O)s2)cc1C(F)(F)F CHEMBL3102903 Activity 0.18 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N)no2)cc1C#N CHEMBL3899384 EC50 0.19 nM
CCCc1ccc(COc2ccc3c(c2C)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)n1 CHEMBL4087932 EC50 0.19 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4[nH]c(CCC(=O)O)cc4c3)no2)cc1Cl CHEMBL2018178 pEC50 0.1995 nM
CCc1c(CCCC(=O)O)cccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL2059515 pEC50 0.1995 nM
CCCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL118860 IC50 0.2 nM
Cc1cc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)ccc1OC(C)C CHEMBL208898 EC50 0.2 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL377767 EC50 0.2 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4cc(-c5ccccc5)c(C(F)(F)F)s4)n3)cc2)C1 CHEMBL225575 EC50 0.2 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCCCCc3ccccc3)cc2)c[nH]1 CHEMBL470511 IC50 0.2 nM
C[C@@](N)(CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O CHEMBL1950574 EC50 0.2 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C(CC)CC)n1 CHEMBL3126587 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)nc(C4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126585 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)nc(C(CC)CC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3124957 EC50 0.2 nM
CCc1cc(-c2noc(-c3ccnc(CC(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126605 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)cc(C4CCCC4)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126619 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)c(N(CC)CC)cn3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126615 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)c(C4CCCC4)cn3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126613 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)c(CC(C)C)cn3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126611 EC50 0.2 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cnc1C1CCCC1 CHEMBL3126624 EC50 0.2 nM
Cc1cc(-c2nc(-c3cc(F)c(O[C@H]4CCC(=O)NC4)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3753943 EC50 0.2 nM
CCc1cc(-c2noc(-c3cc(C)nc(OC(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799305 EC50 0.2 nM
CCC(Nc1ccc(C)c(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671019 IC50 0.2 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CN3CC(C)(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671072 IC50 0.2 nM
CCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL119256 IC50 0.2 nM
Cc1cc([C@@H]2C[C@H]2C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL391870 EC50 0.21 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCCc2ccccc2)cc1 CHEMBL473156 IC50 0.21 nM
CCCc1c(-c2ccccn2)noc1-c1nc(-c2ccc(CN3CC(C(=O)O)C3)cc2)no1 CHEMBL3793145 EC50 0.21 nM
O=C(O)C1CN(Cc2ccc(-c3noc(CCC4(c5ccc(F)cc5)CCCCC4)n3)cc2)C1 CHEMBL3676128 IC50 0.21 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN4CCC[C@H](CC(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL4457691 IC50 0.21 nM
O=C(O)[C@H]1CCCN(CC(O)c2ccc3c(c2)CCc2c(-c4noc(-c5ccccc5)c4C(F)(F)F)noc2-3)C1 CHEMBL4761456 EC50 0.21 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OC(CF)CF)c(C#N)c2)s1 CHEMBL379310 EC50 0.23 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1 CHEMBL1093823 IC50 0.23 nM
COCc1cc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)O)CC4)no2)ccc1-c1ccccc1C CHEMBL3661077 Ki 0.23 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(C(F)(F)F)c1 CHEMBL1093429 IC50 0.24 nM
O=C(O)C1CN(Cc2ccc3c(c2)OCc2c-3noc2-c2onc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL3908750 EC50 0.25 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(CCC(=O)O)c[nH]c4c3)no2)cc1Cl CHEMBL2018177 pEC50 0.2512 nM
CC(C)Oc1ncc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1C(F)(F)F CHEMBL2018306 pEC50 0.2512 nM
CCc1c(CN2CC(C(=O)O)C2)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059686 pEC50 0.2512 nM
CCc1c(CCN2CC(C(=O)O)C2)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059688 pEC50 0.2512 nM
CCc1c(CCN2CC(C(=O)O)C2)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 CHEMBL2057283 pEC50 0.2512 nM
CCCCCCCCOc1ccc(-c2c[nH]c([C@@](C)(N)COP(=O)(O)O)n2)cc1 CHEMBL474689 IC50 0.26 nM
CCCCCCCCOc1ccc(-c2nnc([C@@](C)(N)COP(=O)(O)O)s2)cc1C(F)(F)F CHEMBL3102904 EC50 0.26 nM
CCCCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3799701 EC50 0.27 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL3794064 EC50 0.27 nM
O=C(O)C1CN(Cc2ccc3c(c2)OCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL4757149 EC50 0.27 nM
CCCCCCCCc1ccc(CCC(N)(CO)CO[PH](O)(O)O)cc1 CHEMBL1161691 IC50 0.28 nM
CCC(C)Oc1ccc(-c2nnc(-c3ccc(CCC(=O)O)cc3C)s2)cc1C#N CHEMBL209778 EC50 0.28 nM
CCCCCCCCc1ccc(CCC(N)(CO)OP(=O)(O)O)cc1 CHEMBL117130 IC50 0.3 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Cl CHEMBL119413 IC50 0.3 nM
CCCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL333335 IC50 0.3 nM
Cc1cc(CC(C)C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL241050 EC50 0.3 nM
N[C@H](CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O CHEMBL1950572 EC50 0.3 nM
CCCCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207778 EC50 0.3 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(F)c1 CHEMBL2336064 EC50 0.3 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 CHEMBL2336086 EC50 0.3 nM
CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1 CHEMBL314854 EC50 0.3 nM
N[C@@H](COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1 CHEMBL3102895 Activity 0.3 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C2CCCC2)n1 CHEMBL3126589 EC50 0.3 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C)n1 CHEMBL3126434 EC50 0.3 nM
CCc1cc(-c2noc(-c3ccnc(C(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126603 EC50 0.3 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cnc1N(CC)CC CHEMBL3126608 EC50 0.3 nM
O=C(O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(OC(F)(F)F)c(Cl)c3)cc21 CHEMBL3400916 EC50 0.3 nM
CCc1cc(-c2noc(-c3cnc(C4CCCC4)c(OC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797447 EC50 0.3 nM
CCc1cc(-c2noc(-c3cc(C)nc(OC4CCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800120 EC50 0.3 nM
CCc1cc(-c2noc(-c3cc(OC)nc(C4CCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800133 EC50 0.3 nM
CCc1cc(-c2noc(-c3cc(CC(C)C)nc(OC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799872 EC50 0.3 nM
CCCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1CC(C)C CHEMBL3797951 EC50 0.3 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)sc1CN(C)C CHEMBL3797647 EC50 0.3 nM
CN(C)C(=O)CCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686140 IC50 0.3 nM
Cc1cc([C@@H]2C[C@H]2C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL391581 EC50 0.31 nM
O=C(O)C1CN(Cc2ccc(-c3noc(COCC4(c5ccc(F)cc5)CCCCC4)n3)cc2)C1 CHEMBL3676126 IC50 0.31 nM
CCn1cc(CCC(=O)O)c2cccc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)c21 CHEMBL2018324 pEC50 0.3162 nM
O=C(O)CCCCCc1cnc2oc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1 CHEMBL2032311 pEC50 0.3162 nM
CN(CCCc1ccc2oc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1)CC(=O)O CHEMBL2032429 pEC50 0.3162 nM
CCCCCCCCCc1ccc(CN2CCC(P(=O)(O)O)C2)cc1 CHEMBL184349 IC50 0.33 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2-c2nsc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL4784344 EC50 0.33 nM
O=C(O)C[C@H]1CCCN(CC(O)c2ccc3c(c2)CCc2c(-c4noc(-c5ccccc5)c4C(F)(F)F)noc2-3)C1 CHEMBL4792990 EC50 0.33 nM
CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)c(F)c1 CHEMBL474688 IC50 0.35 nM
CCCCCCCCOc1ccc(-c2c[nH]c([C@@](C)(N)COP(=O)(O)O)n2)cc1F CHEMBL473269 IC50 0.35 nM
COCCS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3931243 EC50 0.36 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OC[C@@H](C)Cc3ccc(F)cc3)ccc21 CHEMBL1935584 EC50 0.37 nM
CC(C)Cc1onc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)c1C(F)(F)F CHEMBL3800091 EC50 0.39 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2ccc(CCC(=O)O)c3c2ccn3C)s1 CHEMBL2011747 pEC50 0.3981 nM
CC(C)Oc1ncc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1Cl CHEMBL2018179 pEC50 0.3981 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCCC(=O)O)c[nH]c34)no2)cc1Cl CHEMBL2018318 pEC50 0.3981 nM
O=C(O)CCCCCc1ccc2oc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1 CHEMBL2032318 pEC50 0.3981 nM
O=C(O)CN1CCN(c2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032435 pEC50 0.3981 nM
O=C(O)C1CN(CCc2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)C1 CHEMBL2032440 pEC50 0.3981 nM
CCc1cc(/C(C)=N/OCc2ccc(C3CCCCC3)c(C(F)(F)F)c2)ccc1CN1CC(C(=O)O)C1 CHEMBL2336071 pEC50 0.3981 nM
CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL441826 IC50 0.4 nM
CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1C CHEMBL119440 IC50 0.4 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Br CHEMBL119354 IC50 0.4 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCCC5)cc4)n3)cc2)C1 CHEMBL198976 IC50 0.4 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(CCC(F)(F)F)cc4)n3)cc2)C1 CHEMBL381872 IC50 0.4 nM
CCOc1ccc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)cc1C(F)(F)F CHEMBL211689 EC50 0.4 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(C2CC2)c1 CHEMBL2336069 EC50 0.4 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(Br)c1 CHEMBL2336066 EC50 0.4 nM
CCc1sc(C(=O)CCc2cc(C)c(OC[C@@H](O)CO)c(C)c2)c2c1CC1(CCCC1)CC2 CHEMBL3121980 EC50 0.4 nM
CCc1sc(C(=O)CCc2cc(C)c(OC[C@@H](O)CO)c(C)c2)c2c1CC(CC)(CC)CC2 CHEMBL3121978 EC50 0.4 nM
CCc1sc(C(=O)CCc2cc(C)c(OC[C@@H](O)CO)c(C)c2)c2c1CC(C)(C)CC2 CHEMBL3121977 EC50 0.4 nM
CCNc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C)n1 CHEMBL3126591 EC50 0.4 nM
CCCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C)n1 CHEMBL3126435 EC50 0.4 nM
CCc1cc(-c2noc(-c3cc(OC)nc(C(CC)CC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800336 EC50 0.4 nM
CCC(Nc1cc(C)cc(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671023 IC50 0.4 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CN3CC[C@@H](C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671040 IC50 0.4 nM
Cc1cc([C@H](Nc2ccc(C)c(CNCCC(=O)O)c2C)C(F)(F)F)ccc1Cl CHEMBL3671051 IC50 0.4 nM
Cc1cc([C@H](Nc2cc(CN3CC[C@@H](C(=O)O)C3)c(Cl)cn2)C(F)(F)F)ccc1Cl CHEMBL3671090 IC50 0.4 nM
CC(C)Oc1ccc(-c2nnc(-c3ccc4c(c3)CC(N)(CO)CC4)o2)cc1C(F)(F)F CHEMBL3897804 IC50 0.4 nM
Cc1cc(C2=NC(c3ccc4c(c3)CC(N)(CO)CC4)N=N2)ccc1OC(C)C CHEMBL3933363 IC50 0.4 nM
O=C(O)CC1OCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3403622 EC50 0.41 nM
Cc1nc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL241052 EC50 0.44 nM
CC(C)Cc1ccc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)cc1C(F)(F)F CHEMBL3358917 EC50 0.44 nM
CCCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3799693 EC50 0.44 nM
CCCc1c(-c2ccccc2)noc1-c1nc(-c2ccc(CN3CC(C(=O)O)C3)cc2)no1 CHEMBL3800257 EC50 0.44 nM
O=C(O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C4CCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358913 EC50 0.45 nM
CC(C)(O)CNC(=O)CCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686125 IC50 0.46 nM
O=C(O)C1CN(Cc2ccc(-c3noc(CCCC4(c5ccc(F)cc5)CCCCC4)n3)cc2)C1 CHEMBL3671363 IC50 0.47 nM
O=C(O)[C@H]1CCCN(CC(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4461520 IC50 0.47 nM
O=C(O)CC1OCCn2c1cc1cc(OCc3ccc(OC(CF)CF)c(Cl)c3)ccc12 CHEMBL3403629 EC50 0.48 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL3930827 EC50 0.48 nM
CCCc1ccc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)cc1C(F)(F)F CHEMBL3358915 EC50 0.49 nM
N#Cc1cc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)ccc1C1CCCC1 CHEMBL3359514 EC50 0.49 nM
Cc1ccccc1-c1ccc(-c2nc(-c3ccc4c(c3)CN(CC(=O)O)CC4)no2)cc1C(F)(F)F CHEMBL3661078 Ki 0.49 nM
CCCCCCCn1nnc(-c2ccc(CNCCCP(=O)(O)O)cc2)n1 CHEMBL119382 IC50 0.5 nM
CCCCCCCc1nc(-c2ccc(CNCCCP(=O)(O)O)cc2)no1 CHEMBL323617 IC50 0.5 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C CHEMBL331054 IC50 0.5 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(C3CCCCC3)cc2)n1 CHEMBL208168 EC50 0.5 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL425563 EC50 0.5 nM
N[C@@H](CC(=O)O)C(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 CHEMBL1950569 EC50 0.5 nM
N[C@@H](CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O CHEMBL1950573 EC50 0.5 nM
CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2cc(C)c(CN3CC(C(=O)O)C3)c(C)c2)s1 CHEMBL2207793 EC50 0.5 nM
Cc1cc(-c2noc(-c3sc(C)c(CC(C)C)c3C)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121966 EC50 0.5 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121989 EC50 0.5 nM
CCc1cc(-c2noc(-c3cc(C)cc(CC(C)C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126617 EC50 0.5 nM
N[C@@H](CO)COc1cc(Cl)c(-c2nnc(N3CCN(C(=O)C4CCCC4)CC3)s2)cc1F CHEMBL3344419 EC50 0.5 nM
N[C@H](COc1cc(Cl)c(-c2nc(N3CCN(C(=O)C4CCCC4)CC3)no2)cc1F)COP(=O)(O)O CHEMBL3341785 EC50 0.5 nM
Cc1cc(-c2nc(-c3ccc(OC[C@H]4COC(=O)N4)c(F)c3)no2)cc(NC(C)C)n1 CHEMBL3754163 EC50 0.5 nM
CC(C)Oc1ncc(-c2nc(-c3cc(F)c(OC[C@H](N)CO)cc3Cl)no2)cc1C#N CHEMBL3753602 EC50 0.5 nM
CCCN(C)Cc1sc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc1CC CHEMBL3799441 EC50 0.5 nM
CCc1cc(-c2noc(-c3cc(C)c(CN(C)CC(C)C)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3798837 EC50 0.5 nM
CNCCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3986508 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCN3CCCC3)no2)cc1C#N CHEMBL3961775 EC50 0.5 nM
CCN(CC)CCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3977589 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CC[C@H](N)C3)no2)cc1C#N CHEMBL3971447 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CC[C@@H](O)C3)no2)cc1C#N CHEMBL3963265 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CC[C@H](O)C3)no2)cc1C#N CHEMBL3910562 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC[C@@H](C)O)no2)cc1C#N CHEMBL3969882 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CCOCC3)no2)cc1C#N CHEMBL3941697 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N[C@@H](C)CO)no2)cc1C#N CHEMBL3985481 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(C)(C)O)no2)cc1C#N CHEMBL3927205 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(C)C(=O)N(C)C)no2)cc1C#N CHEMBL3929906 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC(C)(C)CO)no2)cc1C#N CHEMBL3910164 EC50 0.5 nM
CC(=O)O[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3894218 EC50 0.5 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4O)no2)cc1[N+](=O)[O-] CHEMBL3929478 EC50 0.5 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@H]4O)no2)cc1[N+](=O)[O-] CHEMBL3932230 EC50 0.5 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@H]4O)no2)cc1C(F)(F)F CHEMBL3909636 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4O)no2)cc1C(F)(F)F CHEMBL3917848 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC3CCOCC3)no2)cc1C#N CHEMBL3922297 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCN3CCOCC3)no2)cc1C#N CHEMBL3982194 EC50 0.5 nM
CCN(CC)C(=O)CN[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3969600 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)CN3CCCC3)no2)cc1C#N CHEMBL3910952 EC50 0.5 nM
CCS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3900230 EC50 0.5 nM
CNCCS(=O)(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3923859 EC50 0.5 nM
CC(C)CS(=O)(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3926589 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCN(C)C)no2)cc1C#N CHEMBL3909764 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)c3ccccc3)no2)cc1C#N CHEMBL3957013 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)Cc3ccccc3)no2)cc1C#N CHEMBL3961448 EC50 0.5 nM
CC(C)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3972501 EC50 0.5 nM
COCCN[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3981224 EC50 0.5 nM
CCOc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N)no2)cc1C#N CHEMBL3935588 EC50 0.5 nM
N#Cc1cc(-c2nc(-c3cccc4c3CC[C@H]4N)no2)ccc1OCC1CC1 CHEMBL3980948 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCCO)no2)cc1Br CHEMBL3945024 EC50 0.5 nM
CC(C)COc1ccc(-c2nc(-c3cccc4c3CCC4NCCO)no2)cc1C#N CHEMBL3935123 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N(C)CCO)no2)cc1C#N CHEMBL3895985 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N(CCO)S(C)(=O)=O)no2)cc1C#N CHEMBL3898672 EC50 0.5 nM
CC(=O)N(CCO)[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3955110 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N(C)CC(=O)N(C)C)no2)cc1C#N CHEMBL3915059 EC50 0.5 nM
CCN(CC(=O)N(C)C)[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3917838 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC[C@@H](O)[C@H](O)[C@H](O)CO)no2)cc1C#N CHEMBL3908601 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CC3)no2)cc1C#N CHEMBL3903701 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CCCCC3)no2)cc1C#N CHEMBL3926935 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N3CCN(C)CC3)no2)cc1C#N CHEMBL3892012 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(F)F)no2)cc1C#N CHEMBL3923850 EC50 0.5 nM
CCOC(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3971459 EC50 0.5 nM
CCOC(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3974011 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCc3ccccc3)no2)cc1C#N CHEMBL3897236 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCc3ccccc3)no2)cc1C#N CHEMBL3937491 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCc3cnc[nH]3)no2)cc1C#N CHEMBL3970883 EC50 0.5 nM
Cc1c[nH]c(CN[C@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)n1 CHEMBL3969945 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCc3nc4ccccc4[nH]3)no2)cc1C#N CHEMBL3916866 EC50 0.5 nM
Cc1cc(CN[C@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)[nH]n1 CHEMBL3962124 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCN3CCC3)no2)cc1C#N CHEMBL3904131 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCCC3)no2)cc1C#N CHEMBL3901430 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CC[C@H](O)C3)no2)cc1C#N CHEMBL3947083 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCN3CC[C@@H](O)C3)no2)cc1C#N CHEMBL3918619 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCN3CC[C@H](O)C3)no2)cc1C#N CHEMBL3915866 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCCCC3)no2)cc1C#N CHEMBL3972933 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCOCC3)no2)cc1C#N CHEMBL3961112 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCN3CCOCC3)no2)cc1C#N CHEMBL3982183 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCC(O)CC3)no2)cc1C#N CHEMBL3941503 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCNCC3)no2)cc1C#N CHEMBL3908034 EC50 0.5 nM
COC(=O)C(C)(C)CS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3901636 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N3CC(C(=O)N4CCC4)C3)no2)cc1C#N CHEMBL3917386 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N(C)C)no2)cc1C#N CHEMBL3952397 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCNCC3)no2)cc1C#N CHEMBL3941001 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCC[C@H](O)C3)no2)cc1C#N CHEMBL3939061 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCC(CO)CC3)no2)cc1C#N CHEMBL3926349 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCC[C@@H](O)C3)no2)cc1C#N CHEMBL3948795 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC[C@H](N)C3)no2)cc1C#N CHEMBL3913638 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC[C@@H](N)C3)no2)cc1C#N CHEMBL3924436 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC[C@H](N)C3)no2)cc1C#N CHEMBL3903769 EC50 0.5 nM
COC(=O)CC1CCN(C(=O)N[C@@H]2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)CC1 CHEMBL3932346 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCC(CC(=O)O)CC3)no2)cc1C#N CHEMBL3971247 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CCC(O)CC3)no2)cc1C#N CHEMBL3940768 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC[C@@H](N(C)C)C3)no2)cc1C#N CHEMBL3986043 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC[C@H](N(C)C)C3)no2)cc1C#N CHEMBL3923599 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC[C@@H](N(C)C)C3)no2)cc1C#N CHEMBL3926357 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC[C@H](N(C)C)C3)no2)cc1C#N CHEMBL3912865 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CCC(N(C)C)CC3)no2)cc1C#N CHEMBL3968780 EC50 0.5 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N)no2)cc1S(C)(=O)=O CHEMBL3938436 EC50 0.5 nM
CC[C@@H](Nc1cccc(C(C)N2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671020 IC50 0.5 nM
CC[C@@H](Nc1cc(CN2CC[C@@H](C(=O)O)C2)c(Cl)cn1)c1ccc(Cl)c(C)c1 CHEMBL3671063 IC50 0.5 nM
O=C(O)C1CCCN(CCCc2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)C1 CHEMBL2032438 pEC50 0.5012 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN[C@H]4CCC[C@H]4C(=O)O)cc3)no2)noc1-c1ccccc1 CHEMBL4469843 IC50 0.51 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCc2ccccc2)cc1 CHEMBL514302 EC50 0.52 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL475405 EC50 0.52 nM
CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)c(F)c1 CHEMBL1089557 EC50 0.53 nM
CC(F)(F)c1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3798735 EC50 0.54 nM
O=C(O)C1CN(Cc2ccc(-c3noc(CCCC4(c5ccc(Cl)cc5)CCCCC4)n3)cc2)C1 CHEMBL3676132 IC50 0.54 nM
Clc1cc(-c2noc(CCC3(c4ccccc4)CCCCC3)n2)ccn1 CHEMBL3928616 IC50 0.54 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OC[C@@H](C)Cc3ccc(Cl)cc3)ccc21 CHEMBL1935587 EC50 0.55 nM
CC(C)Cc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3797415 EC50 0.56 nM
CC(C)Cc1onc(-c2onc3c2CCc2cc(CN4CC(C(=O)O)C4)ccc2-3)c1C(F)(F)F CHEMBL3954922 IC50 0.57 nM
CCCc1ccc(COc2ccc3c(c2)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)n1 CHEMBL4074505 EC50 0.58 nM
CCc1ccc(COc2ccc3c(c2)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)c1 CHEMBL4092538 EC50 0.58 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2-c2snc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL4782854 EC50 0.58 nM
N#Cc1cc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)ccc1OC(F)(F)F CHEMBL2048296 EC50 0.59 nM
CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1Cl CHEMBL119116 IC50 0.6 nM
CC(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL194419 IC50 0.6 nM
CC(C)Cc1ccc(-c2nc(COc3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL425428 IC50 0.6 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OCC(F)(F)F)c(C#N)c2)s1 CHEMBL211228 EC50 0.6 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCC(C)c3ccccc3)ccc21 CHEMBL1935579 EC50 0.6 nM
N[C@H](CC(=O)O)C(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 CHEMBL1950568 EC50 0.6 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(Cl)c1 CHEMBL2336065 EC50 0.6 nM
C/C(=N\OCc1ccc(C2CCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 CHEMBL2336085 EC50 0.6 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(N)=O CHEMBL3105487 EC50 0.6 nM
Cc1cc(-c2noc(-c3ccc(CC(C)C)s3)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121969 EC50 0.6 nM
CCc1cc(CCC(=O)c2sc(CC)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121995 EC50 0.6 nM
CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126592 EC50 0.6 nM
Cc1cc(-c2nc(-c3cc(F)c(OC[C@H]4COC(=O)N4)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3754018 EC50 0.6 nM
CCc1cc(-c2noc(-c3cc(OC)c(C4CCCC4)cn3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799953 EC50 0.6 nM
CCc1cc(-c2noc(-c3cc(OC)nc(C4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797626 EC50 0.6 nM
CCCN(C)Cc1sc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc1C CHEMBL3797940 EC50 0.6 nM
Cc1ccccc1-c1ccc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)O)CC4)no2)cc1C(F)(F)F CHEMBL3661081 Ki 0.6 nM
CC[C@@H](Nc1ccc(C)c(CN2CC(C(=O)O)C2)c1C)c1ccc(Cl)c(C)c1 CHEMBL3671044 IC50 0.6 nM
CC[C@@H](Nc1cc(CN2CC(C(=O)O)C2)c(Cl)cn1)c1ccc(Cl)c(C)c1 CHEMBL3671085 IC50 0.6 nM
O=C(O)C1CCN(Cc2ccc(-c3noc(-c4cnn(C5CCCCC5)c4C4CCCO4)n3)cc2)CC1 CHEMBL3701825 Ki 0.6 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OCC3CC3)c(C#N)c2)s1 CHEMBL211826 EC50 0.61 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)cc1C#N CHEMBL2048298 EC50 0.61 nM
CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)c(Cl)c2)cc1 CHEMBL1092577 EC50 0.62 nM
O=C(O)C1CCN(c2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032431 pEC50 0.631 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc([C@@H]5CCC(F)(F)C5)cc4)n3)cc2)N1 CHEMBL209076 IC50 0.64 nM
CCCCCc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)c(Cl)c2)cc1 CHEMBL1096210 EC50 0.64 nM
Cc1nc([C@@](C)(N)COP(=O)(O)O)[nH]c1-c1ccc(OCc2ccc(-c3ccccc3)cc2)c(C(F)(F)F)c1 CHEMBL3102897 Activity 0.65 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCC(C)Cc3ccccc3)ccc21 CHEMBL1935580 EC50 0.66 nM
Cc1cc(S(=O)(=O)Nc2cccc(-c3cc(C)c(C(=O)N(C)[C@@H](CCN(C)C)C(=O)O)c(C)c3)c2)c(C)cc1Cl CHEMBL2178814 Kd 0.67 nM
CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCNC2CC(=O)O)cc1C(F)(F)F CHEMBL3403634 EC50 0.67 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN4CCC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL4440968 IC50 0.69 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1F CHEMBL119873 IC50 0.7 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc(C5CCCCC5)cc4)n3)cc2)N1 CHEMBL210520 IC50 0.7 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2cnc(OC(C)C)c(Cl)c2)n1 CHEMBL210695 EC50 0.7 nM
CCc1cc(/C(C)=N/OCc2ccc(C3CCCCC3)c(C(F)(F)F)c2)ccc1CNCCC(=O)O CHEMBL2336068 EC50 0.7 nM
Cc1cc(-c2nnc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)o2)cc(C)c1OCC(O)CO CHEMBL3105249 EC50 0.7 nM
Cc1cc(-c2nc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)no2)cc(C)c1OC[C@@H](O)CO CHEMBL3105248 EC50 0.7 nM
CCCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccn1 CHEMBL3126602 EC50 0.7 nM
CCc1cc(-c2noc(-c3ccc(CC(C)C)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126626 EC50 0.7 nM
CCc1cc(-c2noc(-c3cnc(OC4CCCC4)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800402 EC50 0.7 nM
CCc1cc(-c2noc(-c3cc(OC)cc(C4CCCC4)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797747 EC50 0.7 nM
CCCCN(C)Cc1sc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc1C CHEMBL3800591 EC50 0.7 nM
O=C(O)[C@@H]1CCCC[C@H]1N[C@@H]1COc2cc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)ccc2[C@@H]1O CHEMBL3640922 IC50 0.7 nM
COCc1cc(-c2nc(-c3ccc4c(c3)CN(CC(=O)O)CC4)no2)ccc1-c1ccccc1C CHEMBL3661072 Ki 0.7 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671075 IC50 0.7 nM
CC[C@@H](Nc1cc(CN2CCC(C)(C(=O)O)C2)c(Cl)cn1)c1ccc(Cl)c(C)c1 CHEMBL3671064 IC50 0.7 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4cnn(C5CCCCC5)c4C4CCOCC4)n3)cc2)C1 CHEMBL3701818 Ki 0.7 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4onc(-c5ccccn5)c4C(F)(F)F)n3)cc2)C1 CHEMBL3794145 EC50 0.71 nM
CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)cc1 CHEMBL475495 IC50 0.73 nM
C[C@](N)(COP(=O)(O)O)c1ncc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)s1 CHEMBL3102901 Activity 0.73 nM
CC(C)Cc1ccc(-c2onc3c2CCc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1C(F)(F)F CHEMBL3942289 EC50 0.73 nM
N#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)c1 CHEMBL2048287 EC50 0.75 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)O)CC4)no2)cc1C(F)(F)F CHEMBL3661079 Ki 0.75 nM
CCCCCCCCc1ccc(CCC(N)COP(=O)(O)O)cc1 CHEMBL432067 IC50 0.76 nM
Cc1ccc(CC(CCCSc2ccc(CNCCCP(=O)(O)O)cc2)c2cccc(Cl)c2)cc1C CHEMBL3092445 EC50 0.76 nM
O=C(O)C1CN(c2cc3c(cc2F)-c2noc(-c4onc(-c5ccccc5)c4C(F)(F)F)c2CC3)C1 CHEMBL3900885 EC50 0.76 nM
Cc1ccccc1-c1ccc(CCOc2ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)cc2)cc1 CHEMBL516380 IC50 0.78 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OC3CCC3)c(C#N)c2)s1 CHEMBL378970 EC50 0.79 nM
CCCCCCCOc1ccc(CC[C@@](C)(N)COP(=O)(O)O)cc1 CHEMBL382739 Log EC50 0.7943 nM
O=C(O)C1CCN(CCCc2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032437 pEC50 0.7943 nM
CCc1c(CCN2CCC(C(=O)O)CC2)cccc1-c1nsc(-c2ccc(CC(C)C)c(C#N)c2)n1 CHEMBL2057285 pEC50 0.7943 nM
CCc1c(CCN2CC(C(=O)O)C2)cccc1-c1nsc(-c2ccc(CC(C)C)c(C#N)c2)n1 CHEMBL2057286 pEC50 0.7943 nM
NC(CO)(CCc1ccc(Sc2cccc(Oc3ccccc3)c2)cc1Cl)COP(=O)(O)O CHEMBL5411968 pEC50 0.7943 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc([C@@H]5CCC(F)(F)C5)cc4)n3)cc2)C1 CHEMBL195014 IC50 0.8 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc([C@H]5CCC(F)(F)C5)cc4)n3)cc2)N1 CHEMBL210257 IC50 0.8 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc([C@@H]5CCC(F)(F)C5)cc4)n3)cc2)C1 CHEMBL208838 IC50 0.8 nM
Cc1cc(CN2CC(C(=O)O)C2)ccc1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL224005 EC50 0.8 nM
Cc1cc([C@H]2C[C@H]2C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL247766 EC50 0.8 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(Cl)c1 CHEMBL1088820 IC50 0.8 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OC[C@@H](O)CO CHEMBL3102993 EC50 0.8 nM
CCc1cc(-c2noc(-c3ccc(C4CCCC4)c(C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126614 EC50 0.8 nM
Cc1cc(-c2nnc(-c3cc(F)c(OC[C@H](N)CO)cc3Cl)s2)cc(CC(C)C)n1 CHEMBL3754270 EC50 0.8 nM
Cc1cc(-c2nc(-c3cc(F)c(OC[C@H]4CCC(=O)N4)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3751872 EC50 0.8 nM
Cc1cc(-c2nc(-c3cc(F)c(O[C@@H]4CCC(=O)NC4)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3753209 EC50 0.8 nM
Cc1cc(-c2nc(-c3cc(F)c(O[C@H]4COC[C@H]4O)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3754653 EC50 0.8 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccc4c(c3)CNCC4)no2)cc1C#N CHEMBL3661070 Ki 0.8 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccc4c(c3)CN(CC(=O)O)CC4)no2)cc1C(F)(F)F CHEMBL3661080 Ki 0.8 nM
CC[C@@H](Nc1ccc(C)c(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671033 IC50 0.8 nM
CC[C@@H](Nc1ccc(C)c(CN2CC(C)(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671039 IC50 0.8 nM
CC[C@@H](Nc1ccc(C)c(CN2CC[C@@H](C(=O)O)C2)c1C)c1ccc(Cl)c(C)c1 CHEMBL3671043 IC50 0.8 nM
CCc1ccc(N[C@@H](c2ccc(Cl)c(C)c2)C(F)(F)F)cc1CN1CC[C@@H](C(=O)O)C1 CHEMBL3671045 IC50 0.8 nM
CC[C@@H](Nc1ccc(Cl)c(CN2CC[C@@H](C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671049 IC50 0.8 nM
Cc1cc([C@H](Nc2cccc(CN3CC(C(=O)O)C3)c2C)C(F)(F)F)ccc1Cl CHEMBL3671050 IC50 0.8 nM
CC[C@@H](Nc1ccc(Cl)c(CN2CC[C@@H](C(=O)O)C2)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671054 IC50 0.8 nM
Cc1cc([C@H](Nc2cccc(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671074 IC50 0.8 nM
Cc1cc(C(Nc2ccc(C(F)(F)F)c(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671076 IC50 0.8 nM
CC[C@@H](Nc1ccnc(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671084 IC50 0.8 nM
O=C(O)CCNCc1ccc(-c2noc(-c3cnn(C4CCCCC4)c3C3CCOCC3)n2)cc1 CHEMBL3701821 Ki 0.8 nM
COCc1cc(-c2nc(-c3cccc(OCC(=O)O)c3)no2)ccc1-c1ccccc1C CHEMBL4076530 Ki 0.8 nM
CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1 CHEMBL1096211 EC50 0.81 nM
O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4ccc(C5CCCC5)c(Cl)c4)n3)ccc21 CHEMBL1916564 EC50 0.82 nM
CCCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccn1 CHEMBL3793185 EC50 0.82 nM
CCCCCCCCOc1ccc(-c2cc([C@@](C)(N)COP(=O)(O)O)[nH]n2)cc1C(F)(F)F CHEMBL3102906 Activity 0.83 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3Cl)cc2)cc1 CHEMBL474407 IC50 0.84 nM
NC(CO)(CCc1ccc(-c2ccc(SCc3ccccc3)cc2F)cc1)COP(=O)(O)O CHEMBL1090819 EC50 0.84 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccc(F)cc3)ccc21 CHEMBL1935576 EC50 0.84 nM
CC(C)Oc1ccc(-c2cn(-c3ccc(CN4CC(C(=O)[O-])C4)cc3)nn2)cc1C(F)(F)F CHEMBL5170826 EC50 0.84 nM
CCCCCCCOc1ccc(CC[C@](C)(N)COP(=O)(O)O)cc1 CHEMBL1084929 EC50 0.85 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OC[C@H](C)Cc3ccc(F)cc3)ccc21 CHEMBL1935583 EC50 0.85 nM
O=C(NCCO)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686139 IC50 0.85 nM
Cc1cc2c(cc1CN1CC(C(=O)O)C1)CCc1c-2noc1-c1noc(-c2ccccc2)c1C(F)(F)F CHEMBL4758827 EC50 0.87 nM
CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207791 EC50 0.89 nM
CCCCCCCCC(=O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL115970 IC50 0.9 nM
CCCCCCc1ccc(-c2ccc(CNCCCP(=O)(O)O)cc2)cc1 CHEMBL116981 IC50 0.9 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc([C@H]5CCC(F)(F)C5)cc4)n3)cc2)C1 CHEMBL198415 IC50 0.9 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(C(F)(F)C(C)C)cn2)n1 CHEMBL209567 EC50 0.9 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL473238 IC50 0.9 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCCCc3ccccc3)cc2)c[nH]1 CHEMBL515917 IC50 0.9 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCNC(=O)CO CHEMBL3105483 EC50 0.9 nM
CCCc1ccc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(C)c3)no2)s1 CHEMBL3121971 EC50 0.9 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCCC4)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3121985 EC50 0.9 nM
CCc1cc(-c2noc(-c3cc(C4CCCC4)cc(C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126596 EC50 0.9 nM
CCc1cc(-c2noc(-c3cnc(C(CC)CC)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126621 EC50 0.9 nM
CCc1cc(-c2noc(-c3cc(C)c(CN(C)C)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800086 EC50 0.9 nM
CC[C@@H](Nc1cccc(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671018 IC50 0.9 nM
Cc1cc([C@H](Nc2ccc(C)c(CN3CC[C@@H](C(=O)O)C3)c2C)C(F)(F)F)ccc1Cl CHEMBL3671041 IC50 0.9 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CNCCC(=O)O)c2)C(F)(F)F)ccc1Cl CHEMBL3671061 IC50 0.9 nM
CC[C@@H](Nc1cc(CN2CC(C(=O)O)C2)c(F)cn1)c1ccc(Cl)c(C)c1 CHEMBL3671062 IC50 0.9 nM
CC[C@@H](Nc1ccc(Cl)c(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671069 IC50 0.9 nM
Cc1cc([C@H](Nc2cc(CNCCC(=O)O)c(Cl)cn2)C(F)(F)F)ccc1Cl CHEMBL3671091 IC50 0.9 nM
Cc1cc(CCC(=O)O)ccc1-c1ccc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL377181 EC50 0.93 nM
Cc1cc(CCC(=O)O)ccc1-n1nnc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL380040 EC50 0.98 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL3800349 EC50 0.98 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2-c2ccc(C3CCCCC3)c(C(F)(F)F)c2)C1 CHEMBL4750972 EC50 0.98 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccc5)c4-c4ccccc4)n3)cc2)C1 CHEMBL3798784 EC50 0.99 nM
CCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O CHEMBL199791 Log EC50 1.0 nM
C[C@@](N)(CCc1ccc(OCCCCCCCCCCCNc2ccc([N+](=O)[O-])c3nonc23)cc1)COP(=O)(O)O CHEMBL371758 Log EC50 1.0 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(C5CCCC5)cc4)n3)cc2)C1 CHEMBL211006 IC50 1.0 nM
COc1ccc2c(c1)CCN(c1noc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n1)C2 CHEMBL1916409 EC50 1.0 nM
COc1ccc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)cc1OC(F)(F)F CHEMBL1916570 EC50 1.0 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(Oc5ccccc5)cc4)n3)s2)C1 CHEMBL1951154 EC50 1.0 nM
O=C(O)CN1CCC(c2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032433 pEC50 1.0 nM
CCc1c(CCCC(=O)O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)nc1 CHEMBL2057232 pEC50 1.0 nM
CCCCN(C(=O)c1ccccc1)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207790 EC50 1.0 nM
Cc1cc(-c2cnc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)o2)cc(C)c1OCC(O)CO CHEMBL3105250 EC50 1.0 nM
CCc1cc(-c2noc(-c3cc(C)nc(C4CCCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126586 EC50 1.0 nM
CCc1cc(-c2noc(-c3cnc(CC(C)C)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126633 EC50 1.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(Cl)cc2)nc2cc(F)c(Cl)cc21 CHEMBL3605517 EC50 1.0 nM
CC(C)c1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccn1 CHEMBL3793394 EC50 1.0 nM
CCc1cc(-c2noc(-c3cc(C)cc(OC4CCCC4)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800028 EC50 1.0 nM
CCc1cc(-c2noc(-c3cc(C)nc(OC4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800019 EC50 1.0 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccc1CN(CC)CC CHEMBL3797596 EC50 1.0 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccc1CN(C)CC CHEMBL3799718 EC50 1.0 nM
COCc1cc(-c2nc(-c3ccc4c(c3)CNCC4)no2)ccc1-c1ccccc1C CHEMBL3661071 Ki 1.0 nM
Cc1cc([C@H](Nc2ccc(C)c(CN3CC[C@@H](C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671032 IC50 1.0 nM
CC[C@@H](Nc1ccc(C)c(CN2CC[C@@H](C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671034 IC50 1.0 nM
Cc1cc([C@H](Nc2ccc(C)c(CN3CC(C(=O)O)C3)c2C)C(F)(F)F)ccc1Cl CHEMBL3671042 IC50 1.0 nM
CC[C@@H](Nc1ccc(C)c(CN2CC[C@@H](C(=O)O)C2)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671053 IC50 1.0 nM
COc1ccc(F)cc1-c1noc(-c2ccc(N3CCCCC3C)c([N+](=O)[O-])c2)n1 CHEMBL3699119 Ki 1.0 nM
COc1ccc(F)cc1-c1noc(-c2ccc(N3CCCCC3)c(C(F)(F)F)c2)n1 CHEMBL3699127 Ki 1.0 nM
COc1cc(CC(C)C)ccc1COc1ccc2c(c1)CCC(CN1CC(C(=O)O)C1)=C2C CHEMBL4085321 EC50 1.0 nM
CCCCOCCOc1nc2c(s1)-c1ccc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)cc1CC2 CHEMBL4279752 EC50 1.0 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN4CCC[C@H](C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL4587424 IC50 1.0 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c-3noc2-c2onc(-c3ccccn3)c2C(F)(F)F)C1 CHEMBL4776597 EC50 1.0 nM
CCc1cc(-c2noc(-c3cc(OC)nc(C4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CO CHEMBL4297505 pEC50 1.0 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)cc2)c[nH]1 CHEMBL514170 IC50 1.03 nM
CC(C)Oc1ccc(COc2ccc3c(c2)CCN(CC(=O)O)C3)cc1C#N CHEMBL5406979 EC50 1.058 nM
O=P(O)(O)CCCNCCCCCCCCCCc1ccccc1 CHEMBL119349 IC50 1.1 nM
COc1cc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)ccc1OC(C)C CHEMBL212580 EC50 1.1 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OC(C)C)c(C#N)c2)o1 CHEMBL211081 EC50 1.1 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OCC(F)F)c(C#N)c2)s1 CHEMBL444799 EC50 1.1 nM
CCCCCc1ccc(CCC(N)(CO)COP(=O)(O)O)c(F)c1 CHEMBL1095889 EC50 1.1 nM
NC(CO)(CCc1ccc(-c2ccc(OCc3ccccc3)cc2F)cc1)COP(=O)(O)O CHEMBL1092272 EC50 1.1 nM
CC(C)Oc1cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)ccc1C#N CHEMBL1916569 EC50 1.1 nM
CC[C@H](COc1ccc2c(c1)CCC(CN1CC(C(=O)O)C1)=C2C)Cc1ccc(F)cc1 CHEMBL1935585 EC50 1.1 nM
Cc1ccc(CCCC(=O)c2ccc(CC[C@@](C)(N)COP(=O)(O)O)n2C)cc1 CHEMBL1951588 EC50 1.1 nM
CCCc1cc(-c2cnc(-c3sc(CN4CC(C(=O)O)C4)cc3CC)s2)ccc1OC(C)C CHEMBL2022905 EC50 1.1 nM
CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2C)s1 CHEMBL2207792 EC50 1.1 nM
C[C@](N)(COP(=O)(O)O)c1ncc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)o1 CHEMBL3102900 Activity 1.1 nM
Cc1cc(-c2noc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)n2)cc(C)c1OC[C@@H](O)CO CHEMBL3105247 EC50 1.1 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCNCC(=O)O CHEMBL3102985 EC50 1.1 nM
Cc1sc(C(=O)CCc2cc(Cl)c(OCCO)c(Cl)c2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL3102988 EC50 1.1 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC3(CC3)C4)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3121987 EC50 1.1 nM
CCc1sc(C(=O)CCc2cc(C)c(OC[C@@H](O)CO)c(C)c2)c2c1CC1(CC2)CC1 CHEMBL3121979 EC50 1.1 nM
O=C(O)CC1CCn2c1cc1cc(OCc3ccc(OCC4CC4)c(C(F)(F)F)c3)ccc12 CHEMBL3359521 EC50 1.1 nM
CCc1cc(-c2noc(-c3cc(C(CC)CC)cc(OC)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797486 EC50 1.1 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(OC2CCCC2)n1 CHEMBL3798969 EC50 1.1 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(OC2CCC2)n1 CHEMBL3799580 EC50 1.1 nM
CCc1cc(-c2noc(-c3cc(CN(C)CC(C)C)cc(C(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799355 EC50 1.1 nM
CCc1cc(CN(C)CC(C)C)cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)c1 CHEMBL3799888 EC50 1.1 nM
COCc1cc(-c2nc(-c3ccc4c(c3)CCN(CCC(=O)O)C4)no2)ccc1-c1ccccc1C CHEMBL3661082 Ki 1.1 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CN3CC(C(=O)O)C3)c2)C(C)C)ccc1Cl CHEMBL3671070 IC50 1.1 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CN3CCC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671079 IC50 1.1 nM
O=C(O)C[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4noc(C5CCCCC5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4473672 EC50 1.1 nM
CCCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL118815 IC50 1.2 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCC2CCCCC2)cc1 CHEMBL473562 IC50 1.2 nM
CCCCOc1cc(F)c(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1F CHEMBL1089558 EC50 1.2 nM
O=C(O)CCc1nc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc2[nH]1 CHEMBL1916558 EC50 1.2 nM
N#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)c1 CHEMBL1916399 EC50 1.2 nM
CCc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121994 EC50 1.2 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNCCC(=O)O CHEMBL3121990 EC50 1.2 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3105484 EC50 1.2 nM
N[C@@H](CO)COc1cc(Cl)c(-c2nc(N3CCN(C(=O)C4CCCCC4)CC3)no2)cc1F CHEMBL3344412 EC50 1.2 nM
CC1(CC(=O)O)OCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3403620 EC50 1.2 nM
CCc1cc(-c2noc(-c3cc(OC)cc(C(CC)CC)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800001 EC50 1.2 nM
CCC(Nc1cccc(C(C)N2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671021 IC50 1.2 nM
CC[C@@H](Nc1ccc(C)c(CNCCC(=O)O)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671056 IC50 1.2 nM
CC[C@@H](Nc1ccc(Cl)c(CNCCC(=O)O)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671059 IC50 1.2 nM
CC[C@@H](Nc1cc(CN2CC[C@@H](C(=O)O)C2)c(Cl)cn1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671066 IC50 1.2 nM
CC[C@@H](Nc1ccc(Cl)c(CN2CC(C)(C(=O)O)C2)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671073 IC50 1.2 nM
Cc1cc([C@H](Nc2cccc([C@H](C)NCCC(=O)O)c2)C(F)(F)F)ccc1Cl CHEMBL3671080 IC50 1.2 nM
Cc1ccsc1-c1noc(COCC2(c3ccc(Cl)cc3)CCC2)n1 CHEMBL3891659 IC50 1.2 nM
CCCc1ccc(-c2onc3c2COc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1 CHEMBL3911661 IC50 1.2 nM
Cc1cc(-c2noc(-c3ccc4c(c3)CCC(N)(CO)C4)n2)ccc1OC(C)C CHEMBL3945798 IC50 1.2 nM
O=C(O)CCNCc1ccc2sc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)cc2c1 CHEMBL4579553 EC50 1.2 nM
O=C(O)C[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4458575 EC50 1.2 nM
Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(CC(=O)N[C@@H](C)CO)C2 CHEMBL1836171 pEC50 1.259 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2ccc(S(=O)(=O)NCCC(=O)O)cc2)s1 CHEMBL2011736 pEC50 1.259 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2cccc3[nH]ccc23)s1 CHEMBL2011739 pEC50 1.259 nM
O=C(O)CC1CCN(c2ccc3oc(-c4ccc(-c5ccccc5)c(C(F)(F)F)c4)nc3c2)CC1 CHEMBL2032432 pEC50 1.259 nM
CCc1c(CCCC(=O)O)cccc1-c1nnc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL2059516 pEC50 1.259 nM
CCc1c(CCCC(=O)O)cccc1-c1nc(-c2ccc(OC(C)C)c(C#N)c2)ns1 CHEMBL2059518 pEC50 1.259 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(CC(C)C)c(C#N)c2)n1 CHEMBL2059671 pEC50 1.259 nM
CCOc1ccc(-c2nc(-c3cccc4c3CCC4NCCO)no2)cc1OCC CHEMBL3922179 pEC50 1.259 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br CHEMBL332667 IC50 1.3 nM
CCC(C)(C)c1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL372066 IC50 1.3 nM
CCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL194578 IC50 1.3 nM
Cc1cc(CN2CC(C(=O)O)C2)cc(C)c1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL224853 EC50 1.3 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(F)c2)C1 CHEMBL389880 EC50 1.3 nM
CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1F CHEMBL1091630 EC50 1.3 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(Br)c1 CHEMBL1089127 IC50 1.3 nM
O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4ccc(-c5cccs5)c(C(F)(F)F)c4)n3)ccc21 CHEMBL1916565 EC50 1.3 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(OC(C)C)c(C(C)C)c2)s1 CHEMBL2022906 EC50 1.3 nM
CCCCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CN3CCC(C(=O)O)C3)cc2)s1 CHEMBL2207779 EC50 1.3 nM
Cc1cc(-c2noc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3105478 EC50 1.3 nM
CCc1cc(CCC(=O)c2sc(OC)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121998 EC50 1.3 nM
CCc1cc(CCC(=O)c2sc(C(F)(F)F)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121997 EC50 1.3 nM
CCCc1sc(C(=O)CCc2cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c2)c2c1CC(C)(C)CC2 CHEMBL3121996 EC50 1.3 nM
CCc1cc(-c2noc(-c3cc(C)cc(N(CC)CC)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126597 EC50 1.3 nM
CCc1cc(-c2noc(-c3cc(CC(C)C)cc(C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126618 EC50 1.3 nM
CC(C)c1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3800513 EC50 1.3 nM
CCc1cc(-c2noc(-c3cc(C)c(CN(C)CC)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797412 EC50 1.3 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccc1CN(C)C CHEMBL3799916 EC50 1.3 nM
CC[C@@H](Nc1ccc(C)c(CN2CC(C(=O)O)C2)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671052 IC50 1.3 nM
Cc1cc([C@@H](C)Nc2ccc(Cl)c(CN3CC[C@@H](C(=O)O)C3)c2)cc(C)c1Cl CHEMBL3671057 IC50 1.3 nM
CCCc1ccc(-c2noc3c2COc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1 CHEMBL3946363 IC50 1.3 nM
CC1(c2onc(-c3onc4c3CCc3cc(CN5CC(C(=O)O)C5)ccc3-4)c2C(F)(F)F)CC1 CHEMBL4757437 EC50 1.3 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2c(-c4onc(-c5ccccc5)c4C(F)(F)F)noc2-3)C1 CHEMBL4747682 EC50 1.3 nM
CCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117910 IC50 1.4 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCCCC5)cc4)n3)cc2)C1 CHEMBL196534 IC50 1.4 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(C5CCCCC5)cc4)n3)cc2)C1 CHEMBL377828 IC50 1.4 nM
CCc1cc(CN2CC(C(=O)O)C2)ccc1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL375488 EC50 1.4 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(Cl)c2)C1 CHEMBL224571 EC50 1.4 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cn1 CHEMBL2336061 EC50 1.4 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCN CHEMBL3103658 EC50 1.4 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OC[C@H](O)CO CHEMBL3103656 EC50 1.4 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC(C)(C)C4)n2)cc(C)c1OCCNCCC(=O)O CHEMBL3121961 EC50 1.4 nM
O=C(O)CC1CCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3403621 EC50 1.4 nM
Cc1cc(-c2nc(-c3cnc(OC[C@H]4COC(=O)N4)c(C)c3)no2)cc(CC(C)C)n1 CHEMBL3752968 EC50 1.4 nM
CCc1cc(-c2noc(-c3ccc(C4CCCC4)c(OC)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3798690 EC50 1.4 nM
COc1cc(C)ccc1COc1ccc2c(c1)CCC(CN1CC(C(=O)O)C1)=C2C CHEMBL4071753 EC50 1.4 nM
CCCCCCCCOc1ccc(-c2cnc([C@@](C)(N)COP(=O)(O)O)[nH]2)cc1C(F)(F)F CHEMBL3102909 Activity 1.46 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL332373 IC50 1.5 nM
COc1cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)ccc1OC(F)F CHEMBL1916568 EC50 1.5 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(O)CNCC(=O)O CHEMBL3105481 EC50 1.5 nM
Cc1cc(-c2noc(-c3cc(CC(C)C)c(C)s3)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121968 EC50 1.5 nM
Cc1cc(-c2noc(-c3scc(CC(C)C)c3C)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121967 EC50 1.5 nM
CCc1cc(-c2noc(-c3sc(C)c4c3CCC(C)(C)C4)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3122000 EC50 1.5 nM
CCc1cc(-c2noc(-c3cnc(OC)c(C4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799227 EC50 1.5 nM
CCc1cc(-c2noc(-c3cc(OC)cc(CC(C)C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797365 EC50 1.5 nM
CC[C@@H](Nc1cccc(CN2CC(C)(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671022 IC50 1.5 nM
CCC(Nc1cccc(CN2CC[C@@H](C(=O)O)C2)c1C)c1ccc(Cl)c(C)c1 CHEMBL3671027 IC50 1.5 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN)cc3)no2)noc1-c1ccccc1 CHEMBL4475594 IC50 1.5 nM
CC(C)Oc1ccc(-c2onc3c2CCc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1C(F)(F)F CHEMBL3970572 EC50 1.5 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2cccc3c2c(Cl)cn3CCC(=O)O)s1 CHEMBL2010813 pEC50 1.585 nM
Cc1cc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cnc1OC(C)C CHEMBL2018307 pEC50 1.585 nM
CCc1c(CCCC(=O)O)cccc1-c1ccc(-c2ccc(OC(C)C)c(C#N)c2)cc1 CHEMBL2059527 pEC50 1.585 nM
Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(Cl)c3)s1)CCN(CCC(=O)O)C2 CHEMBL3769933 pEC50 1.585 nM
Cc1cc(CCC(=O)O)ccc1-c1nnn(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL210345 EC50 1.6 nM
Cc1cc(S(N)(=O)=O)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1088177 EC50 1.6 nM
NC(CO)(CCc1ccc(-c2ccc(OCc3ccccc3)cc2)cc1Cl)COP(=O)(O)O CHEMBL1090223 EC50 1.6 nM
O=C(O)C1CN(Cc2ccc(-c3nnc(N(CC4CC4)C(=O)c4ccccc4F)s3)cc2)C1 CHEMBL2207784 EC50 1.6 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CN2CC(C(=O)O)C2)c(C)c1 CHEMBL2336070 EC50 1.6 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)cs1 CHEMBL3102899 Activity 1.6 nM
Cc1cc(-c2noc(-c3sc(C)c4c3CCC(C)(C)C4)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121964 EC50 1.6 nM
CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(C)CC2 CHEMBL3121981 EC50 1.6 nM
CCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3800595 EC50 1.6 nM
CCC(Nc1ccc(C)c(C(C)N2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671024 IC50 1.6 nM
Cc1cc(C(Nc2cccc(CN3CC(C(=O)O)C3)c2)C(C)C)ccc1Cl CHEMBL3671029 IC50 1.6 nM
Cc1ccc(N[C@H](C)c2cc(C)c(Cl)c(C)c2)cc1CNCCC(=O)O CHEMBL3671058 IC50 1.6 nM
CC[C@@H](Nc1ccc(Cl)c(CN2CC(C(=O)O)C2)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671068 IC50 1.6 nM
CCOc1ccc(-c2onc3c2CCc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1OCC CHEMBL4793933 EC50 1.6 nM
CN1Cc2c(noc2-c2onc(-c3ccccc3)c2C(F)(F)F)-c2ccc(CN3CC(C(=O)O)C3)cc21 CHEMBL4763970 EC50 1.6 nM
O=C(O)C1CN(Cc2cc3c(cc2F)-c2noc(-c4noc(-c5ccccc5)c4C(F)(F)F)c2CC3)C1 CHEMBL4764300 EC50 1.6 nM
CS(=O)(=O)CCNC(=O)C(O)c1ccc2c(c1)CCc1c(-c3noc(-c4ccccc4)c3C(F)(F)F)noc1-2 CHEMBL4758481 EC50 1.6 nM
N[C@@H](CC(=O)N1CCc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21)C(=O)O CHEMBL1916563 EC50 1.63 nM
O=C(O)C1CN(Cc2ccc(-c3noc(CCCC4(c5ccccc5)CCCCC4=O)n3)cc2)C1 CHEMBL3671364 IC50 1.68 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(-c5ccccc5)cc4)n3)cc2)C1 CHEMBL195025 IC50 1.7 nM
CCc1cc(-c2noc(-c3scc4c3CCC(C)(C)C4)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121999 EC50 1.7 nM
N#Cc1cc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)ccc1OC(F)(F)F CHEMBL3358906 EC50 1.7 nM
N[C@@H](CO)COc1cc(Cl)c(-c2nc(N3CCN(C(=O)C4CCCC4)CC3)no2)cc1F CHEMBL3344410 EC50 1.7 nM
CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCOC2CC(=O)O)cc1C#N CHEMBL3403628 EC50 1.7 nM
CN1CCn2c(c(Cl)c3cc(OCc4cc(C#N)cc(OC(F)(F)F)c4)ccc32)C1CC(=O)O CHEMBL3403635 EC50 1.7 nM
Cc1c(-c2ccccc2)noc1-c1nc(-c2ccc(CN3CC(C(=O)O)C3)cc2)no1 CHEMBL3799276 EC50 1.7 nM
Cc1cc([C@H](Nc2ccc(Cl)c(CN3CC(C(=O)O)C3)c2)C(C)C)cc(C)c1Cl CHEMBL3671071 IC50 1.7 nM
N#CC1(NC(=O)C(O)c2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)CC1 CHEMBL3909064 EC50 1.7 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCC3CCc4ccccc43)ccc21 CHEMBL4093077 EC50 1.7 nM
C[C@](N)(COP(=O)(O)O)c1nnc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)s1 CHEMBL3102902 Activity 1.77 nM
CC(C)Oc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL196357 IC50 1.8 nM
Cc1ccc(Oc2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)cc2)cc1 CHEMBL1092284 EC50 1.8 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(Cl)c1OCCO CHEMBL3102989 EC50 1.8 nM
CCc1cc(-c2noc(-c3sc(OC)c4c3CCC(C)(C)C4)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3121975 EC50 1.8 nM
CCCCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccn1 CHEMBL3126604 EC50 1.8 nM
CCc1ccc(N[C@@H](c2ccc(Cl)c(C)c2)C(F)(F)F)cc1CN1CC(C(=O)O)C1 CHEMBL3671046 IC50 1.8 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4cnn(CC5CC5)c4-c4ccncc4)n3)cc2)C1 CHEMBL3701820 Ki 1.8 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN[C@@H]4CCC[C@@H]4C(=O)O)cc3)no2)noc1-c1ccccc1 CHEMBL4452807 IC50 1.8 nM
CC(C)Oc1ccc(-c2cn(-c3ccc(CN4CC(C(=O)[O-])C4)cc3)nn2)cc1C#N CHEMBL5174924 EC50 1.84 nM
CC(C)Oc1ccc(-c2cn(-c3ccc(CN4CC(C(=O)[O-])C4)cc3)nn2)cc1Cl CHEMBL5177759 EC50 1.87 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1OC CHEMBL118508 IC50 1.9 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(F)c2)n1 CHEMBL380253 EC50 1.9 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(-c3cccs3)c(C#N)c2)s1 CHEMBL210038 EC50 1.9 nM
CCCCCCCCOc1ccc(-c2noc([C@@](C)(N)COP(=O)(O)O)n2)cc1C(F)(F)F CHEMBL3102908 Activity 1.9 nM
CCc1cc(-c2noc(-c3cc(C)nc(N4CCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126593 EC50 1.9 nM
CCc1cc(-c2noc(-c3cnc(CC(C)C)c(C)c3)n2)cc(C)c1OC[C@H](O)CNC(=O)CO CHEMBL3126634 EC50 1.9 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H](C)N[C@H]4C[C@@H](C(=O)O)C4)cc3)no2)cc1 CHEMBL3752339 EC50 1.9 nM
CC[C@@H](Nc1cccc(CN2CC(C(=O)O)C2)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671030 IC50 1.9 nM
CC[C@@H](Nc1cccc(CN2CC(C(=O)O)C2)c1F)c1ccc(Cl)c(C)c1 CHEMBL3671035 IC50 1.9 nM
Nc1ncccc1-c1noc(CCC2(c3ccccc3)CCCCC2)n1 CHEMBL3935426 IC50 1.9 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059670 pEC50 1.995 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(N3CCCCC3)c(C(F)(F)F)c2)n1 CHEMBL2059675 pEC50 1.995 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNCC4)no2)cc1C#N CHEMBL3360363 pEC50 1.995 nM
CCOCCCC1CCc2cc(C3CCC(N)(CO)C3)ccc2C1 CHEMBL5438034 pEC50 1.995 nM
CCCCCCCCCc1ccc(CNCCCP(C)(=O)O)cc1 CHEMBL432809 IC50 2.0 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc(C5CCCC5)c(F)c4)n3)cc2)N1 CHEMBL426688 IC50 2.0 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(C5CCC(F)(F)CC5)cc4)n3)cc2)C1 CHEMBL208648 IC50 2.0 nM
Cc1nn(C(=O)/C=C/c2cccc3[nH]ccc23)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL601062 EC50 2.0 nM
Cc1cccc(Sc2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)c(F)c2)c1 CHEMBL1089809 EC50 2.0 nM
O=C(O)C1CN(Cc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)c(F)c2)C1 CHEMBL1651861 EC50 2.0 nM
O=C(O)CNCCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 CHEMBL1950566 EC50 2.0 nM
N[C@H](CC(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O CHEMBL1950570 EC50 2.0 nM
N[C@@H](CC(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O CHEMBL1950571 EC50 2.0 nM
CCCCN(C(=O)Cc1ccccc1)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207788 EC50 2.0 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(C)c1 CHEMBL2336067 EC50 2.0 nM
Cc1cc([C@@H](C)Nc2cccc(-c3cc(C)c(C(=O)N[C@@H](C)C(=O)O)c(C)c3)c2)ccc1Cl CHEMBL3086703 IC50 2.0 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(O)CN1CC(C(=O)O)C1 CHEMBL3105482 EC50 2.0 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C2CCCCC2)n1 CHEMBL3126590 EC50 2.0 nM
CCCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3739878 IC50 2.0 nM
O=C(O)C1CN(Cc2ccc(CCc3ccccc3)cc2)C1 CHEMBL3741743 IC50 2.0 nM
CC[C@@H](Nc1cccc(CN2CC(C(=O)O)C2)c1)c1ccc2c(Cl)cccc2c1 CHEMBL3671031 IC50 2.0 nM
OCc1ccc(-c2noc(-c3cnn(C4CCCCC4)c3C3CCCO3)n2)cc1 CHEMBL3701823 Ki 2.0 nM
Cc1nnc(CNC(=O)C(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)o1 CHEMBL3686126 IC50 2.0 nM
COc1ccccc1-c1noc(-c2ccc(-c3ccccc3C)c([N+](=O)[O-])c2)n1 CHEMBL3699115 Ki 2.0 nM
COc1ccccc1-c1noc(-c2ccc(-c3cscc3C)c(C(F)(F)F)c2)n1 CHEMBL3699126 Ki 2.0 nM
Cc1cc(S(=O)(=O)NCCC(=O)O)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1082869 Ki 2.0 nM
Cc1cc([C@H](C)Nc2cccc(-c3cc(C)c(C(=O)N[C@@H](C)C(=O)O)c(C)c3)c2)ccc1Cl CHEMBL5403266 IC50 2.0 nM
c1cc(-c2c(-c3nc(-c4ccc(Cn5ccnc5)cc4)no3)cnn2C2CCCCC2)ccn1 CHEMBL3701829 Ki 2.065 nM
CCOc1ccc(-c2nnc(-c3ccc(CCC(=O)O)cc3C)s2)cc1C#N CHEMBL208897 EC50 2.1 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2cnc(OC(C)C)c(Cl)c2)s1 CHEMBL212420 EC50 2.1 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)CC(F)OP(=O)(O)O)cc1 CHEMBL226612 EC50 2.1 nM
C=P(O)(O)OCC(N)(CO)CCc1ccc(-c2ccc(SCc3ccccc3)cc2)cc1Cl CHEMBL1092285 EC50 2.1 nM
O=C(O)CC1CCn2c1cc1cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc12 CHEMBL2048295 EC50 2.1 nM
Cc1cc(S(=O)(=O)Nc2cccc(-c3cc(C)c(C(=O)N[C@@H](CCN)C(=O)O)c(C)c3)c2)c(C)cc1Cl CHEMBL2178812 IC50 2.1 nM
Cc1oc([C@@](C)(N)COP(=O)(O)O)nc1-c1ccc(OCc2ccc(-c3ccccc3)cc2)c(C(F)(F)F)c1 CHEMBL3102898 Activity 2.1 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccn1 CHEMBL3126601 EC50 2.1 nM
CCc1cc(-c2noc(-c3cnc(N(CC)CC)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126625 EC50 2.1 nM
CC(C)Cc1ccc(COc2ccc3c(c2)cc2n3CCNC2CC(=O)O)cc1C(F)(F)F CHEMBL3403633 EC50 2.1 nM
CCc1cc(-c2noc(-c3cc(C)cc(CN(C)CC(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799686 EC50 2.1 nM
CC[C@@H](Nc1cc(CN2CC(C(=O)O)C2)ccc1F)c1ccc(Cl)c(C)c1 CHEMBL3671037 IC50 2.1 nM
CC[C@@H](Nc1cc(CN2CC[C@@H](C(=O)O)C2)c(C)cn1)c1ccc(Cl)c(C)c1 CHEMBL3671067 IC50 2.1 nM
O=C(NCc1cnco1)[C@H](O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686145 IC50 2.1 nM
Cc1ccccc1-c1ccc(-c2nc(-c3ccc(CN(C)CCC(=O)O)c(F)c3)no2)cc1C(F)(F)F CHEMBL5194177 IC50 2.13 nM
CC(C)CCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207785 EC50 2.17 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCC5)cc4)n3)cc2)C1 CHEMBL194898 IC50 2.2 nM
O=C(O)CC1CNC(c2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL377855 IC50 2.2 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)cc2)c[nH]1 CHEMBL474418 EC50 2.2 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)s1 CHEMBL2336062 EC50 2.2 nM
Cc1ccc(CCCC(=O)c2cc(C)c(COC[C@@](C)(N)COP(=O)(O)O)c(C)c2)cc1 CHEMBL3311353 EC50 2.2 nM
CCc1nc(-c2ccc(-c3ccc(CC[C@](N)(CO)COP(=O)(O)O)cc3)cc2)co1 CHEMBL4641924 EC50 2.2 nM
CC(C)Oc1ccc(-n2cc(-c3ccc(CN4CC(C(=O)[O-])C4)cc3)nn2)cc1Cl CHEMBL5172303 EC50 2.25 nM
CCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL334213 IC50 2.3 nM
CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL432813 IC50 2.3 nM
CCCCCCCOC(=O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL117403 IC50 2.3 nM
NC(CO)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1 CHEMBL3102896 Activity 2.3 nM
CCc1cc(C(=O)CCCc2ccc(C)cc2)ccc1COC[C@@](C)(N)COP(=O)(O)O CHEMBL3311352 EC50 2.3 nM
N[C@@H](CO)COc1cc(Cl)c(-c2nnc(N3CCN(C(=O)c4cccc(Cl)c4)CC3)s2)cc1F CHEMBL3344420 EC50 2.3 nM
O=C(O)CC1CCCn2c1cc1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12 CHEMBL3400906 EC50 2.3 nM
CCC(Nc1cc(C)cc(CN2CC[C@@H](C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671028 IC50 2.3 nM
CC(C)Cn1ncc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)c1-c1ccncc1 CHEMBL3701816 Ki 2.3 nM
CC(C)Cc1onc(-c2nc(-c3ccc([C@H](O)CN4CCC[C@H](CC(=O)O)C4)cc3)no2)c1C(F)(F)F CHEMBL4529165 EC50 2.3 nM
CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117715 IC50 2.4 nM
Cc1ccccc1-c1noc(-c2ccc(C3CCCCC3)cc2)n1 CHEMBL208786 EC50 2.4 nM
O=C(O)C1CCN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL224799 EC50 2.4 nM
CCCCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CNCCC(=O)O)cc2)s1 CHEMBL2207777 EC50 2.4 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC(C)(C)C4)n2)cc(C)c1OC[C@@H](C)CO CHEMBL3120183 EC50 2.4 nM
CC[C@@H](Nc1ccc(C)c(CNC[C@@H](C)C(=O)O)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671060 IC50 2.4 nM
CCCc1ccc(-c2nc(-c3cccc4c3CCN4CC(N)(CO)CO)no2)cc1CCC CHEMBL3944892 EC50 2.4 nM
O=C(O)C[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4onc(-c5ccccn5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4476492 EC50 2.4 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2nc(-c4onc(-c5ccccc5)c4C(F)(F)F)sc2-3)C1 CHEMBL4755286 EC50 2.4 nM
CCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL118265 IC50 2.5 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1OCC CHEMBL324820 IC50 2.5 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL473563 IC50 2.5 nM
Cc1cc(-c2nc(-c3cnc(OC[C@H]4COC(=O)N4)c(C)n3)no2)cc(NC(C)C)n1 CHEMBL3752473 EC50 2.5 nM
CCc1ccc(N[C@H](CC)c2ccc(Cl)c(C)c2)cc1CN1CC(C(=O)O)C1 CHEMBL3671048 IC50 2.5 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(ccn4CCC(=O)O)c3)no2)cc1Cl CHEMBL2018174 pEC50 2.512 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL2059517 pEC50 2.512 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CNC(CCC(=O)O)CO4)no2)cc1Cl CHEMBL3359851 pEC50 2.512 nM
CCC/N=C1\S/C(=C\c2ccc(C(=O)OC)c(Cl)c2)C(=O)N1c1ccccc1C CHEMBL4280697 pIC50 2.512 nM
Cc1cc(S(=O)(=O)Nc2cccc(-c3cc(C)c(C(=O)N[C@@H](C)C(=O)O)c(C)c3)c2)c(C)cc1Cl CHEMBL2178809 IC50 2.6 nM
C/C(=N\OCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)nc1 CHEMBL2336087 EC50 2.6 nM
CNCCOc1c(C)cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc1C CHEMBL3105489 EC50 2.6 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCO CHEMBL3102987 EC50 2.6 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OC[C@@H](O)CO CHEMBL3122005 EC50 2.6 nM
CCCCN(C)Cc1cc(C)cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)c1 CHEMBL3799086 EC50 2.6 nM
CNC(=O)[C@H](C)NC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686133 IC50 2.6 nM
N#CC1(NC(=O)C(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)CC1 CHEMBL3686134 IC50 2.6 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3F)ccc21 CHEMBL4084786 EC50 2.6 nM
Cc1ccc(CC(CCCSc2ccc(CNCCCP(=O)(O)O)cc2)c2cc(F)cc(F)c2)cc1C CHEMBL3092446 EC50 2.65 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL475253 EC50 2.67 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc(C5CCCC5)cc4F)n3)cc2)N1 CHEMBL210782 IC50 2.7 nM
O=C(O)C1CN(Cc2cc(Cl)c(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(Cl)c2)C1 CHEMBL426191 EC50 2.7 nM
CCc1ccc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)cc1C(F)(F)F CHEMBL1916572 EC50 2.7 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3F)ccc21 CHEMBL1935578 EC50 2.7 nM
Cc1cc(CCC(=O)c2sc(C)c(CC(C)C)c2C)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121962 EC50 2.7 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OCC(C)C)c(C#N)c2)s1 CHEMBL207275 EC50 2.8 nM
CCc1nc(CN2CC(C(=O)O)C2)ccc1-c1cnc(-c2ccc(OC(C)C)c(C)c2)s1 CHEMBL2022915 EC50 2.8 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCN1CC(C(=O)O)C1 CHEMBL3102986 EC50 2.8 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cnc1N1CCCC1 CHEMBL3126610 EC50 2.8 nM
Cc1ccc(CCCC(=O)c2ccc(COC[C@@](C)(N)COP(=O)(O)O)c(F)c2)cc1 CHEMBL3311350 EC50 2.8 nM
Cc1cc(-c2nc(-c3ccc(OC[C@H]4COC(=O)N4)cc3)no2)cc(NC(C)C)n1 CHEMBL3753059 EC50 2.8 nM
CCc1cc(-c2noc(-c3cc(C)c(CN(C)CCO)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797357 EC50 2.8 nM
CCCc1cc(CN(C)CC(C)C)cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)c1 CHEMBL3800604 EC50 2.8 nM
CC[C@@H](Nc1cc(CN2CC(C(=O)O)C2)ccn1)c1ccc(Cl)c(C)c1 CHEMBL3671082 IC50 2.8 nM
CCCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL193789 IC50 2.9 nM
CCCN(c1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2C)ncn1)C1CCCCC1 CHEMBL1088178 EC50 2.9 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCCc3ccccc3)ccc21 CHEMBL1797509 EC50 2.9 nM
COc1ccc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)cc1C#N CHEMBL2048297 EC50 2.9 nM
Cc1cc([C@H](Nc2ccc(C)c(CN3CCC(C)(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl CHEMBL3671089 IC50 2.9 nM
O=C(NCCC(=O)N1CC(O)C1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686143 IC50 2.9 nM
O=C(Nc1ccc(CN2CC(C(=O)O)C2)cc1)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL3918272 EC50 2.9 nM
CCCOc1ccc(-c2nc(-c3ccc4c(c3)CCN4CC(N)(CO)CO)no2)cc1Br CHEMBL3918061 EC50 2.9 nM
COCc1cc(-c2nc(-c3ccc(-c4ccc(C(=O)O)c(F)c4)cc3)no2)ccc1-c1ccccc1C CHEMBL4085783 Ki 2.9 nM
Cc1cc(CN2CC(C(=O)O)C2)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1083828 EC50 3.0 nM
Cc1ccc(Sc2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)c(F)c2)cc1 CHEMBL1089475 EC50 3.0 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3)ccc21 CHEMBL1935575 EC50 3.0 nM
O=C(O)CNCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 CHEMBL1950481 EC50 3.0 nM
O=C(O)CCNCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 CHEMBL1950563 EC50 3.0 nM
C[C@](N)(CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O CHEMBL1950575 EC50 3.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3C)cc2)n1 CHEMBL1951312 EC50 3.0 nM
CCCCN(C(=O)c1ccccc1OC)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207786 EC50 3.0 nM
Cc1nn(C(=O)/C=C/c2cc(F)ccc2F)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL3103683 EC50 3.0 nM
Cc1ccc(CCCC(=O)c2ccc(COC[C@@](C)(N)COP(=O)(O)O)c(C)c2)cc1 CHEMBL3311348 EC50 3.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(C#N)cc2)nc2cnc(C(F)(F)F)cc21 CHEMBL3605554 EC50 3.0 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccc4c(c3)CNCC4)no2)cc1C(F)(F)F CHEMBL3661068 Ki 3.0 nM
COc1cc(-c2nc(-c3ccc4[nH]ncc4c3)no2)ccc1-c1cscc1C CHEMBL3661074 Ki 3.0 nM
CC[C@@H](Nc1ccc(C)c(CN(C)CCC(=O)O)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671088 IC50 3.0 nM
CC(C)Cn1cc(-c2nc(-c3cc(F)ccc3F)no2)c(-c2ccccc2)n1 CHEMBL3698530 Ki 3.0 nM
COc1ccccc1-c1noc(-c2ccc(-c3cscc3C)c(C)c2)n1 CHEMBL3699114 Ki 3.0 nM
COc1ccccc1-c1noc(-c2ccc(N3CCCCC3C)c(C(F)(F)F)c2)n1 CHEMBL3699122 Ki 3.0 nM
COc1ccc(F)cc1-c1noc(-c2ccc(N3CCCCC3C)c(C(F)(F)F)c2)n1 CHEMBL3699130 Ki 3.0 nM
CCCN(CCC)c1cc(C(=O)Nc2ccc3[nH]ncc3c2)ncn1 CHEMBL1080880 Ki 3.0 nM
Cc1cc(-c2nnc(-c3ccc4c(c3)CC(N)(CO)CC4)o2)ccc1OC(C)C CHEMBL3916072 IC50 3.0 nM
COc1cc(COc2ccc3c(c2)CCC(CN2CC(C(=O)O)C2)=C3C)ccc1CC(C)C CHEMBL4095501 EC50 3.0 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3)ccc21 CHEMBL1962532 EC50 3.0 nM
CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1Cl CHEMBL1089564 EC50 3.1 nM
CC1(C)CC(C(=O)N2CCN(c3noc(-c4cc(F)c(OC[C@@H](N)CO)cc4Cl)n3)CC2)C1 CHEMBL3344405 EC50 3.1 nM
Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(CO)CO)C2 CHEMBL1836215 pEC50 3.162 nM
CCOc1ccc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1OCC CHEMBL2018309 pEC50 3.162 nM
CCc1c(CCCC(=O)O)cccc1-c1nnc(-c2ccc(OC(C)C)c(C#N)c2)o1 CHEMBL2059519 pEC50 3.162 nM
CCc1c(CCCC(=O)O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL2059520 pEC50 3.162 nM
Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(CCC(=O)O)C2 CHEMBL3770858 pEC50 3.162 nM
CCOc1ccc(-c2nc(-c3ccncc3)no2)cc1OCC CHEMBL1452805 pEC50 3.162 nM
COc1ccc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)cc1C(F)(F)F CHEMBL211806 EC50 3.2 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(OC(C)C)c(Cl)c2)s1 CHEMBL2022908 EC50 3.2 nM
N#Cc1cc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)ccc1OC(F)(F)F CHEMBL2048290 EC50 3.2 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccc5)c4C4CC4)n3)cc2)C1 CHEMBL3798775 EC50 3.2 nM
CCc1cc(-c2noc(-c3cc(C)nc(CN(C)CC(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799026 EC50 3.2 nM
O=C(NCCO)C(O)c1ccc(-c2noc(-c3noc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686137 IC50 3.2 nM
COCCN(c1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2C)ncn1)C1CCCCC1 CHEMBL3958225 Ki 3.2 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4CC[C@@H](CC(=O)O)N4)cc3)no2)cc1 CHEMBL210352 IC50 3.3 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(Br)c2)C1 CHEMBL224599 EC50 3.3 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCNS(C)(=O)=O CHEMBL3105246 EC50 3.3 nM
CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCCC2CC(=O)O)cc1C(F)(F)F CHEMBL3403623 EC50 3.3 nM
CC[C@@H](Nc1cccc(CN2CC[C@@H](C(=O)O)C2)c1F)c1ccc(Cl)c(C)c1 CHEMBL3671036 IC50 3.3 nM
N#CCc1ccc(-c2noc(-c3cnn(C4CCCCC4)c3-c3ccncc3)n2)cc1 CHEMBL3701842 Ki 3.3 nM
c1ccc(-c2noc(CCC3(c4ccccc4)CCCCC3)n2)cc1 CHEMBL3984700 IC50 3.3 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(CC(C)C)cn2)n1 CHEMBL209566 EC50 3.4 nM
CCCOc1ccc(-c2nnc(-c3ccc(CCC(=O)O)cc3C)s2)cc1C#N CHEMBL212266 EC50 3.4 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(C#N)c1 CHEMBL1088819 IC50 3.4 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(OC(C)C)c(C)c2)s1 CHEMBL2022903 EC50 3.4 nM
CCc1cc(-c2cnc(-c3sc(CN4CC(C(=O)O)C4)cc3CC)s2)ccc1OC(C)C CHEMBL2022904 EC50 3.4 nM
CNC(=O)COc1c(C)cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc1C CHEMBL3105488 EC50 3.4 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OC[C@H](O)CO CHEMBL3122006 EC50 3.4 nM
CCc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccn1 CHEMBL3792704 EC50 3.4 nM
c1cc(-c2c(-c3nc(-c4ccc(Cn5ncnn5)cc4)no3)cnn2C2CCCCC2)ccn1 CHEMBL3701840 Ki 3.4 nM
O=C(O)C1CN(Cc2ccc(-c3noc(C/C=C/C4(c5ccc(F)cc5)CCCCC4)n3)cc2)C1 CHEMBL3676133 IC50 3.4 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(C(C)C)c(C)c2)s1 CHEMBL2022909 EC50 3.5 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCNC(CC(=O)O)C(=O)O CHEMBL3105480 EC50 3.5 nM
Cc1cc(-c2nc(-c3cc(F)c(O[C@@H]4CNC(=O)C4)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3752499 EC50 3.5 nM
CCc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)ccc1CN1CCCC1 CHEMBL3797541 EC50 3.5 nM
CCC(Nc1cccc(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671017 IC50 3.5 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN4CC(N)(CO)CO)no2)cc1Cl CHEMBL3945943 EC50 3.5 nM
CCCCc1ccc(COc2ccc3c(c2)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)c1 CHEMBL4065871 EC50 3.5 nM
O=C(O)[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4448752 EC50 3.5 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)CCP(=O)(O)O)cc1 CHEMBL228139 EC50 3.6 nM
NC(CO)(CCc1ccc(-c2ccc(Sc3ccccc3)cc2F)cc1)COP(=O)(O)O CHEMBL1092286 EC50 3.6 nM
CCc1cc(-c2noc(-c3cc(C)cc(CN(C)CC)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799748 EC50 3.6 nM
O=C(O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C4CC4)c(C(F)(F)F)c3)cc21 CHEMBL3358914 EC50 3.68 nM
CCc1ccc(N[C@H](CC)c2ccc(Cl)c(C)c2)cc1CN1CC[C@@H](C(=O)O)C1 CHEMBL3671047 IC50 3.7 nM
CC(C)(C)c1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL195141 IC50 3.8 nM
CC(C)(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL366181 IC50 3.8 nM
COc1ccccc1CCC(=O)n1nc(C)c2c1C[C@@H]1[C@H]2C1(C)C CHEMBL3103670 EC50 3.8 nM
O=C(O)CN[C@@H]1COc2cc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)ccc2[C@@H]1O CHEMBL3640924 IC50 3.8 nM
CCc1cc(-c2noc(-c3ccc(C(C)C)nc3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126630 EC50 3.9 nM
CC[C@@H](Nc1ccc(C)c(CNC[C@H](C)C(=O)O)c1)c1cc(C)c(Cl)c(C)c1 CHEMBL3671087 IC50 3.9 nM
O=C(O)C[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4522539 EC50 3.9 nM
CCc1c(CCCC(=O)O)cccc1-c1ccc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL2059521 pEC50 3.981 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 CHEMBL2059669 pEC50 3.981 nM
CCc1c(CN2CC(C(=O)O)C2)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 CHEMBL2059689 pEC50 3.981 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CC(=O)O)CC4)no2)cc1C#N CHEMBL3359845 pEC50 3.981 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCNC4)no2)cc1C#N CHEMBL3360364 pEC50 3.981 nM
CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCN(CCC(=O)O)C4)s2)cc1Cl CHEMBL3769584 pEC50 3.981 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@@H](N)COP(=O)(O)O)n2)cc1 CHEMBL190865 EC50 4.0 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)cc1Br CHEMBL1916571 EC50 4.0 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3cccc(F)c3)ccc21 CHEMBL1935577 EC50 4.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3)cc2)n1 CHEMBL1951304 EC50 4.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3OC)cc2)n1 CHEMBL1951311 EC50 4.0 nM
CCc1cc(-c2cnc(-c3ccc(CN4CC(C(=O)O)C4)nc3CC)s2)ccc1OC(C)C CHEMBL2022914 EC50 4.0 nM
Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)c2)c(=O)c2ccc(CCC(=O)O)cc21 CHEMBL2037128 EC50 4.0 nM
Cc1ccc(CCCC(=O)c2ccc(COC[C@@](C)(N)COP(=O)(O)O)c(Cl)c2)cc1 CHEMBL3311351 EC50 4.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(C#N)nc2)nc2cnc(C3CC3)cc21 CHEMBL3605558 EC50 4.0 nM
Cc1cc(-c2nc(-c3cc(F)c(OC[C@H](N)CO)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3753931 EC50 4.0 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccc4c(c3)CNCC4)no2)cc1NS(C)(=O)=O CHEMBL3661069 Ki 4.0 nM
CC[C@@H](Nc1cccc(CN2CC[C@@H](C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 CHEMBL3671025 IC50 4.0 nM
COc1ccccc1-c1noc(-c2ccc(-c3cscc3C)c(OC)c2)n1 CHEMBL3699124 Ki 4.0 nM
Cc1cscc1-c1ccc(-c2nc(-c3ccccc3OC(F)(F)F)no2)cc1C(F)(F)F CHEMBL3699131 Ki 4.0 nM
COc1ccc(F)cc1-c1noc(-c2ccc(N3CCCCC3C)c(C#N)c2)n1 CHEMBL3699132 Ki 4.0 nM
COc1ccc(F)cc1-c1noc(-c2ccc(-c3ccccc3C)c(CN(C)C)c2)n1 CHEMBL3699136 Ki 4.0 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN4CCC[C@@H](CC(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL4464631 IC50 4.0 nM
COC(=O)C1CN(Cc2ccc(-n3cc(-c4ccc(OC(C)C)c(C(F)(F)F)c4)nn3)cc2)C1 CHEMBL5179798 EC50 4.06 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117723 IC50 4.1 nM
CCc1nc(CN2CC(C(=O)O)C2)ccc1-c1cnc(-c2ccc(CC(C)C)c(C)c2)s1 CHEMBL2022916 EC50 4.1 nM
N[C@@H](CO)COc1cc(Cl)c(-c2nc(N3CCN(C(=O)c4cccc(Cl)c4)CC3)no2)cc1F CHEMBL3344415 EC50 4.1 nM
CC(=O)N1CCOC[C@@H]1COc1cc(Cl)c(-c2noc(-c3cc(C)nc(NC(C)C)c3)n2)cc1F CHEMBL3752984 EC50 4.1 nM
CC(C)Oc1ccc(-c2nc(-c3cc(F)c(OC[C@H](N)CO)cc3Cl)no2)cc1Cl CHEMBL3754035 EC50 4.1 nM
CCCN(C)Cc1cc(C)cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)c1 CHEMBL3798240 EC50 4.1 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(C(=O)CCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL1090796 IC50 4.14 nM
Cc1ccc(Sc2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)c(Cl)c3)c(F)c2)cc1 CHEMBL1089810 EC50 4.2 nM
O=C(O)CCCCn1cc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc2n1 CHEMBL1916405 EC50 4.2 nM
CCC1CCCCN1c1ccc(-c2nc(-c3ccc4nc[nH]c4c3)no2)cc1COC CHEMBL3661076 Ki 4.26 nM
FC(F)(F)c1cc(-c2nc(-c3ccc4[nH]cnc4c3)no2)cc(C(F)(F)F)c1 CHEMBL1916553 EC50 4.3 nM
CCc1ccc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(C)c3)no2)s1 CHEMBL3121972 EC50 4.3 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CN1CC(C(=O)O)C1 CHEMBL3121991 EC50 4.3 nM
CCCCN(C)Cc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C)n1 CHEMBL3799148 EC50 4.3 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(=O)NCCO CHEMBL3105245 EC50 4.4 nM
CCc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCO CHEMBL3102990 EC50 4.4 nM
CCc1cc(-c2noc(-c3ccc(CC(C)C)c(C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126612 EC50 4.4 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CC5)cc4)n3)cc2)C1 CHEMBL371985 IC50 4.5 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4CC[C@@H](CCC(=O)O)N4)cc3)no2)cc1 CHEMBL377637 IC50 4.5 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OC[C@H](Cc3ccc(F)cc3)C(C)C)ccc21 CHEMBL1935586 EC50 4.5 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3C(C)C)cc2)n1 CHEMBL1951315 EC50 4.5 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(Oc3ccccc3)cc2)s1 CHEMBL2022900 EC50 4.5 nM
CCc1cc(-c2noc(-c3cc(C4CCCC4)cc(OC)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799976 EC50 4.5 nM
O=C(NC1CNC1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686131 IC50 4.5 nM
O=C(NC1CCS(=O)(=O)C1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686132 IC50 4.5 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3Cl)ccc21 CHEMBL4075067 EC50 4.5 nM
O=C(O)CC1CCc2c1[nH]c1ccc(OCc3ccc(CC4CCCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358918 EC50 4.58 nM
O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21 CHEMBL1916559 EC50 4.6 nM
COc1ccc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)cc1C#N CHEMBL2048291 EC50 4.6 nM
COc1cc(C#N)cc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)c1 CHEMBL2048294 EC50 4.6 nM
COc1cc(OCCO)ccc1CCC(=O)c1sc(C)c2c1C[C@@H]1[C@H]2C1(C)C CHEMBL3103662 EC50 4.6 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC(C)(C)C4)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3122001 EC50 4.6 nM
CCCc1ccc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cn1 CHEMBL3126629 EC50 4.6 nM
c1cc(-c2c(-c3nc(-c4ccc(CCn5cncn5)cc4)no3)cnn2C2CCCCC2)ccn1 CHEMBL3701841 Ki 4.6 nM
CC(C)Oc1ccc(-c2onc3c2CCc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1C#N CHEMBL4744056 EC50 4.6 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(C)(N)COP(=O)(O)O)n2)cc1 CHEMBL188881 EC50 4.7 nM
NC(CO)(CCc1ccc(-c2ccc(Oc3ccccc3)cc2)cc1Cl)COP(=O)(O)O CHEMBL1093574 EC50 4.7 nM
CCCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207783 EC50 4.7 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCO CHEMBL3102992 EC50 4.7 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC(C)(C)C4)n2)cc(C)c1OCCC(=O)O CHEMBL3121960 EC50 4.7 nM
CCCCc1ccc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(C)c3)no2)s1 CHEMBL3121970 EC50 4.7 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC3(CCCC3)C4)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3121988 EC50 4.7 nM
CCC(c1cccc(N[C@H](CC)c2ccc(Cl)c(C)c2)c1)N1CC(C(=O)O)C1 CHEMBL3671026 IC50 4.7 nM
COc1ccc(CCCCOc2ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)cc2)cc1 CHEMBL516035 IC50 4.75 nM
O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccc(F)cc2)CN1C(=O)Cn1nccn1 CHEMBL2018573 IC50 4.8 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(O)CNCCO CHEMBL3102984 EC50 4.8 nM
CCc1cc(CCC(=O)c2scc3c2CCC(C)(C)C3)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3121993 EC50 4.8 nM
CCCCCCCCCCCCCC1CCCC(CCP(C)(=O)O)N1 CHEMBL187692 IC50 4.9 nM
O=C(O)CCCn1ncc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21 CHEMBL1916404 EC50 4.9 nM
O=C(NCc1ccccn1)[C@H](O)c1ccc(-c2noc(-c3cnn(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686147 IC50 4.9 nM
COC(=O)C1CN(Cc2ccc(-c3cn(-c4ccc(OC(C)C)c(Cl)c4)nn3)cc2)C1 CHEMBL5202775 EC50 4.91 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3)c(F)c2)n1 CHEMBL1951316 EC50 5.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3)c(Cl)c2)n1 CHEMBL1951317 EC50 5.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(Cl)cc2)nc2ccc(CO)cc21 CHEMBL3605520 EC50 5.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(Cl)cc2)nc2ccc(C(F)(F)F)cc21 CHEMBL3605516 EC50 5.0 nM
CCCCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3739440 IC50 5.0 nM
Cc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3800122 EC50 5.0 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccc4nc[nH]c4c3)no2)cc1C(F)(F)F CHEMBL3661064 Ki 5.0 nM
COCc1cc(-c2nc(-c3ccc4nc[nH]c4c3)no2)ccc1-c1ccccc1C CHEMBL3661066 Ki 5.0 nM
Cc1ccccc1-c1ccc(-c2nc(-c3ccc4nc[nH]c4c3)no2)cc1CN(C)C CHEMBL3661067 Ki 5.0 nM
CS(=O)(=O)c1cccc(-c2noc(-c3cnn(-c4ccccc4F)c3-c3ccncc3)n2)c1 CHEMBL3701809 Ki 5.0 nM
Fc1ccc(F)c(-c2noc(-c3cnn(C4CCCCC4)c3-c3ccncc3)n2)c1 CHEMBL3701814 Ki 5.0 nM
CC1CCCCN1c1ccc(-c2nc(-c3ccccc3OC(F)(F)F)no2)cc1C(F)(F)F CHEMBL3699121 Ki 5.0 nM
Cc1cc(-c2nc(-c3ccccc3OC(F)(F)F)no2)ccc1-c1cscc1C CHEMBL3699123 Ki 5.0 nM
Cc1cc(-c2cn(-c3ccc4c(c3)CCC(N)(CO)C4)nn2)ccc1OC(C)C CHEMBL3908980 IC50 5.0 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3)ccc21 CHEMBL4103252 EC50 5.0 nM
CCc1nc(-c2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)cc2)co1 CHEMBL3782062 EC50 5.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c(C(=O)O)c[nH]c34)no2)cc1Cl CHEMBL2018316 pEC50 5.012 nM
CCc1c(CCCC(=O)O)cccc1-c1cc(-c2ccc(OC(C)C)c(C#N)c2)no1 CHEMBL2059522 pEC50 5.012 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2cnc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL2059672 pEC50 5.012 nM
CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(-c3ccccc3)c(C(F)(F)F)c2)n1 CHEMBL2059676 pEC50 5.012 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4CCC(=O)O)no2)cc1Cl CHEMBL3359852 pEC50 5.012 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CNC(C(=O)O)CO4)no2)cc1Cl CHEMBL3359850 pEC50 5.012 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4CC(=O)O)no2)cc1C#N CHEMBL3359849 pEC50 5.012 nM
CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCN(CCC(=O)O)C4)s2)cc1C#N CHEMBL3770458 pEC50 5.012 nM
CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCN(CCCC(=O)O)C4)s2)cc1Cl CHEMBL3769451 pEC50 5.012 nM
Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(CCC(=O)O)C2 CHEMBL1836169 pEC50 5.012 nM
CC(C)Oc1ccc(C2CC(c3ccc(CN4CC(C(=O)[O-])C4)cc3)=NO2)cc1C(F)(F)F CHEMBL5183779 EC50 5.09 nM
CCOc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL371743 IC50 5.1 nM
Cc1cc(CCC(=O)O)ccc1-c1ncc(-c2ccc(OC(C)C)c(C#N)c2)o1 CHEMBL209003 EC50 5.1 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCNCCO CHEMBL3105490 EC50 5.1 nM
CCc1cc(-c2noc(-c3ccnc(CCC(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3422425 EC50 5.1 nM
CCc1cc(-c2nc(-c3cc(C)c(CCC(=O)NCCO)c(CC)c3)no2)cnc1N(C)C(C)C CHEMBL3799324 EC50 5.1 nM
c1cnn(Cc2ccc(-c3noc(-c4cnn(C5CCCCC5)c4-c4ccncc4)n3)cc2)c1 CHEMBL3701830 Ki 5.16 nM
CCCCCCCc1ccc(CCCNCCCP(=O)(O)O)cc1 CHEMBL119233 IC50 5.3 nM
O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4ccc(Cl)c(OC(F)(F)F)c4)n3)ccc21 CHEMBL1916573 EC50 5.3 nM
CCc1cccnc1C(=O)N1CCN(c2noc(-c3cc(F)c(OC[C@@H](N)CO)cc3Cl)n2)CC1 CHEMBL3344418 EC50 5.3 nM
CC(C)(C)c1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL3798531 EC50 5.3 nM
CCCCN(C)Cc1ccc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc1C CHEMBL3798068 EC50 5.3 nM
COc1ccccc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(C(C)C)c1 CHEMBL2017807 EC50 5.4 nM
CCc1cc(-c2ncc(-c3ccc(CN4CC(C(=O)O)C4)nc3CC)s2)ccc1CC(C)C CHEMBL2022917 EC50 5.4 nM
CCc1cc(-c2noc(-c3ccc(CN(C)C)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3797921 EC50 5.4 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(CCC(F)(F)F)cc4)n3)cc2)C1 CHEMBL425602 IC50 5.5 nM
CCc1nc(CN2CC(C(=O)O)C2)ccc1-c1ncc(-c2ccc(OC(C)C)c(C)c2)s1 CHEMBL2022913 EC50 5.5 nM
O=C(O)C1CN(Cc2ccc3c(c2)CCc2nc(-c4onc(-c5ccccc5)c4C(F)(F)F)oc2-3)C1 CHEMBL4760972 EC50 5.5 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H]4CC[C@@H](CCC(=O)O)N4)cc3)no2)cc1 CHEMBL210468 IC50 5.7 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4C[C@H](CC(=O)O)CN4)cc3)no2)cc1 CHEMBL378300 IC50 5.7 nM
CCC/N=C1\S/C(=C\c2ccc(OC[C@@H](O)CO)c(Cl)c2)C(=O)N1c1ccccc1C CHEMBL1095833 EC50 5.7 nM
CCc1cc(-c2noc(-c3ccc(CC(C)C)nc3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126627 EC50 5.7 nM
Cc1cc([C@H](Nc2cccc(CN3CC(C(=O)O)C3)c2)C2CCC2)ccc1Cl CHEMBL3671083 IC50 5.7 nM
Cc1cc(-c2noc(/C=C/C3(c4ccc(Cl)cc4)CCCCC3)n2)cc(C)c1OC[C@@H](O)CO CHEMBL3676127 IC50 5.75 nM
O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccc(F)cc2)CN1C(=O)Cn1cncn1 CHEMBL2018485 IC50 5.8 nM
O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccc(F)cc2)CN1C(=O)Cn1ccnn1 CHEMBL2018571 IC50 5.8 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(OC(C)C)c(F)c2)s1 CHEMBL2022907 EC50 5.8 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)ccc1OCCO CHEMBL3103667 EC50 5.8 nM
CNS(=O)(=O)c1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)c(C)c1 CHEMBL1087909 EC50 5.8 nM
O=C(O)C1CN(CC(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4545842 IC50 5.8 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(C(F)(F)F)c2)C1 CHEMBL224549 EC50 5.9 nM
Cc1cc2[nH]ncc2cc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1080382 EC50 6.0 nM
Cc1cc(NC(=O)[C@@](C)(N)COP(=O)(O)O)ccc1OCCc1ccc(-c2ccccc2)cc1 CHEMBL1093424 IC50 6.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(O[C@@H](C)CC)c(C)c2)s1 CHEMBL2022910 EC50 6.0 nM
CCc1cc(-c2noc(-c3sc(CC)c4c3CCC(CC)(CC)C4)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3121986 EC50 6.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(C#N)cc2)nc2cnc(C3CC3)cc21 CHEMBL3605555 EC50 6.0 nM
Cc1cc(-c2nc(-c3cc(F)c(OC[C@H]4OCC[C@@H]4O)cc3Cl)no2)cc(NC(C)C)n1 CHEMBL3752436 EC50 6.0 nM
c1cc(-c2c(-c3nc(-c4ccc(Cn5cnnn5)cc4)no3)cnn2C2CCCCC2)ccn1 CHEMBL3701845 Ki 6.0 nM
COc1ccc(F)cc1-c1noc(-c2cnc(N3CCCCC3C)c(C)c2)n1 CHEMBL3699134 Ki 6.0 nM
CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCCC(=O)O)cc2C)ncn1 CHEMBL1086157 Ki 6.0 nM
O=C(Nc1cccc2[nH]ccc12)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL3914648 EC50 6.0 nM
CCCCCCCCc1ccc(CCC(N)(CO)CCP(=O)(O)O)cc1 CHEMBL114584 IC50 6.0 nM
COc1ccc(F)cc1-c1noc(-c2ccc(-c3ccccc3C)c(C)c2)n1 CHEMBL3699120 EC50 6.0 nM
O=C(O)CCN1CCc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21 CHEMBL1916560 EC50 6.1 nM
Cc1cc(S(=O)(=O)Nc2cccc(-c3cc(C)c(C(=O)N(C)[C@@H](C)C(=O)O)c(C)c3)c2)c(C)cc1Cl CHEMBL2178810 IC50 6.1 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCCN CHEMBL3122007 EC50 6.1 nM
CCCCCCCCc1ccc(CCNCCCP(=O)(O)O)cc1 CHEMBL325193 IC50 6.3 nM
COc1ccc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)cc1C#N CHEMBL1916574 EC50 6.3 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCC(CO)CO CHEMBL3103657 EC50 6.3 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2ccc(F)c3[nH]ccc23)s1 CHEMBL2011742 pEC50 6.31 nM
COc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c2c1c(CCC(=O)O)cn2C CHEMBL2018327 pEC50 6.31 nM
CC(C)Oc1ncc(-c2nc3cc(CCCCCC(=O)O)cnc3o2)cc1C(F)(F)F CHEMBL2032310 pEC50 6.31 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCC(=O)O)C4)no2)cc1C#N CHEMBL3359842 pEC50 6.31 nM
CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCN(CCCC(=O)O)C4)s2)cc1C#N CHEMBL3771073 pEC50 6.31 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@@H](N)COP(O)(O)=S)n2)cc1 CHEMBL188826 EC50 6.4 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)cc1C(F)(F)F CHEMBL1090828 IC50 6.4 nM
CCc1cc(-c2noc(-c3sc(CN(C)C)c(C)c3C)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3800102 EC50 6.4 nM
COC(=O)C1CN(Cc2ccc(-n3cc(-c4ccc(OC(C)C)c(C#N)c4)nn3)cc2)C1 CHEMBL5176185 EC50 6.49 nM
O=C(O)C1CN(Cc2cc(-c3noc(-c4cc(-c5ccccc5)c(C(F)(F)F)s4)n3)cs2)C1 CHEMBL1951147 EC50 6.5 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3Cl)cc2)n1 CHEMBL1951310 EC50 6.5 nM
CCc1ccccc1Oc1ccc(-c2nc(-c3sc(CN4CC(C(=O)O)C4)cc3CC)no2)cc1 CHEMBL1951313 EC50 6.5 nM
Cc1sc(C(=O)CCc2ccc(OCCO)cc2Cl)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL3103663 EC50 6.5 nM
Cc1ccc(CCCC(=O)c2cc(C)c(COC[C@@](C)(N)COP(=O)(O)O)cc2C)cc1 CHEMBL3311354 EC50 6.5 nM
N[C@@H](CO)COc1cc(Cl)c(-c2nc(N3CCN(C(=O)c4ccccc4)CC3)no2)cc1F CHEMBL3344414 EC50 6.5 nM
CC(C)Cn1ncc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)c1C1CCOCC1 CHEMBL3701817 Ki 6.5 nM
CCCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL117973 IC50 6.6 nM
O=C(O)CCCC(=O)N1CCc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21 CHEMBL1916561 EC50 6.6 nM
Cc1cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc(C)c1OCCCN CHEMBL3105492 EC50 6.6 nM
CCc1c(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(C)c3)no2)sc(C)c1CC(C)C CHEMBL3121965 EC50 6.6 nM
O=C(O)[C@@H]1CCC[C@@H](N[C@@H]2COc3cc(-c4noc(-c5onc(-c6ccccc6)c5C(F)(F)F)n4)ccc3[C@@H]2O)C1 CHEMBL3640923 IC50 6.6 nM
COc1cc(CC(C)(C)O)ccc1COc1ccc2c(c1)CCC(CN1CC(C(=O)O)C1)=C2C CHEMBL4101237 EC50 6.6 nM
C=CCN(c1ccccc1)S(=O)(=O)c1cc(Cl)cc(Cl)c1 CHEMBL1916400 EC50 6.7 nM
O=C(O)CC1CCn2c1cc1cc(OCc3ccc(OCF)c(C(F)(F)F)c3)ccc12 CHEMBL3359518 EC50 6.7 nM
Cc1ccc(N[C@H](C)c2cc(C)c(Cl)c(C)c2)cc1CN1CC[C@@H](C(=O)O)C1 CHEMBL3671055 IC50 6.7 nM
O=C(NCc1ncc[nH]1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686127 IC50 6.7 nM
CCCc1ccc(-c2nc(-c3cccc4c3CCN4CC(N)(CO)CO)no2)cc1 CHEMBL3959942 EC50 6.7 nM
OCc1ccc(-c2noc(-c3ccc(OCC[18F])c(C(F)(F)F)c3)n2)cc1 CHEMBL5205276 IC50 6.7 nM
COc1ccccc1C(=O)NC(=O)Nc1ccc(OCC(F)(F)F)c(C(F)(F)F)c1 CHEMBL2017811 EC50 6.8 nM
O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](Cc2ccccc2)CN1C(=O)Cn1cncn1 CHEMBL2018484 IC50 6.8 nM
CNCCCOc1c(C)cc(CCC(=O)c2sc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc1C CHEMBL3105493 EC50 6.8 nM
N#Cc1cc(COc2ccc3c(c2)cc2n3CCOC2CC(=O)O)cc(OC(F)(F)F)c1 CHEMBL3403625 EC50 6.8 nM
CCc1cc(-c2noc(-c3ccc(CN(C)CC)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3799109 EC50 6.8 nM
CCOc1ccc(-c2nc(-c3cccc4c3CCN4CC(N)(CO)CO)no2)cc1OCC CHEMBL3941765 EC50 6.8 nM
O=C(O)C1CN(Cc2ccc3c(c2)Cc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1 CHEMBL4797042 EC50 6.8 nM
CCCCCCCCCCCCCC[C@H]1CC[C@H](CCP(=O)(O)O)N1 CHEMBL187588 IC50 6.9 nM
CCCCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL115738 IC50 7.0 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@H](N)COP(=O)(O)O)n2)cc1 CHEMBL187712 EC50 7.0 nM
Cc1nn(C(=O)/C=C/c2ccncc2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL590383 EC50 7.0 nM
CCc1cc(-c2noc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)n2)cc(C)c1CCC(=O)O CHEMBL3105479 EC50 7.0 nM
Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CN CHEMBL3122010 EC50 7.0 nM
Cc1ccc(CCCC(=O)c2ccc(COC[C@@](C)(N)COP(=O)(O)O)cc2)cc1 CHEMBL3311106 EC50 7.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(F)cc2)nc2ccc(C(F)(F)F)cc21 CHEMBL3605533 EC50 7.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(C#N)nc2)nc2cnc(C(F)(F)F)cc21 CHEMBL3605557 EC50 7.0 nM
CCc1nc(-c2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)cc2)co1 CHEMBL3781008 EC50 7.0 nM
CC(C)Cn1ncc(-c2nc(-c3cc(F)ccc3F)no2)c1-c1ccccc1 CHEMBL3701811 Ki 7.0 nM
COc1ccccc1-c1noc(-c2ccc(N3CCOCC3)c(C(F)(F)F)c2)n1 CHEMBL3699110 Ki 7.0 nM
CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2C)ncn1 CHEMBL3898098 Ki 7.0 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN4CCCCC4CC(=O)O)cc3)no2)noc1-c1ccccc1 CHEMBL4553546 IC50 7.0 nM
CC(C)Oc1ccc(C2CC(c3ccc(CN4CC(C(=O)[O-])C4)cc3)=NO2)cc1Cl CHEMBL5176383 EC50 7.03 nM
CCc1cc(-c2noc(-c3ccc(CN(C)C)c(C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3798420 EC50 7.1 nM
FC(F)(F)c1cc(-c2nc(-c3ccc4[nH]ncc4c3)no2)cc(C(F)(F)F)c1 CHEMBL1916402 EC50 7.2 nM
CCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL325247 IC50 7.3 nM
Cc1cc(-c2nc(-c3ccc(OC[C@H]4COC(=O)N4)nc3)no2)cc(NC(C)C)n1 CHEMBL3753881 EC50 7.3 nM
CCc1cc(-c2noc(-c3cc(OC)nc(C4CCCCC4)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3798839 EC50 7.3 nM
CCOc1ccc(-c2nc(-c3ccc4c(c3)CN(CC(N)(CO)CO)C4)no2)cc1OCC CHEMBL3971409 EC50 7.4 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3)c(C)c2)n1 CHEMBL1951319 EC50 7.5 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)cc1C#N CHEMBL2048292 EC50 7.5 nM
CC(C)Oc1ccc(C#Cc2ccc(Cn3ccnc3)cc2Cl)cc1C#N CHEMBL4100453 EC50 7.5 nM
COc1ccc(-c2nc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)co2)cc1 CHEMBL3341918 EC50 7.6 nM
CCCCCCCCCc1ccc(CNCCCC(=O)O)cc1 CHEMBL432632 IC50 7.7 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OCCC(F)(F)F)c(C#N)c2)s1 CHEMBL380235 EC50 7.7 nM
Cc1cc(CCC(=O)c2ccc(CC(C)C)s2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3121963 EC50 7.7 nM
CCCCCCCCc1ccc(CNCCCC(=O)O)cc1 CHEMBL4072987 IC50 7.7 nM
CC(C)Cc1onc(-c2nc(-c3ccc([C@H](O)CN4CCC[C@H](C(=O)O)C4)cc3)no2)c1C(F)(F)F CHEMBL4520384 EC50 7.8 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(N)(CO)COP(=O)(O)O)n2)cc1 CHEMBL537849 EC50 7.9 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4C[C@@H](CC(=O)O)CN4)cc3)no2)cc1 CHEMBL378061 IC50 7.9 nM
Cc1cc(-c2nc(-c3ccc(OC[C@H]4COC(=O)N4)c(C)n3)no2)cc(NC(C)C)n1 CHEMBL3753282 EC50 7.9 nM
CCc1cc(-c2nnc(-c3cc(C)nc(N(CC)CC)c3)o2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126595 EC50 7.9 nM
CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCC3Cc4ccccc4C3)ccc21 CHEMBL4100785 EC50 7.9 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(CO)CO)C4)no2)cc1C#N CHEMBL1836214 pEC50 7.943 nM
CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2cccc3c2ccn3C)s1 CHEMBL2011740 pEC50 7.943 nM
CCc1c(CN2CC(C(=O)O)C2)cccc1-c1nsc(-c2ccc(CC(C)C)c(C#N)c2)n1 CHEMBL2057284 pEC50 7.943 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCCC(=O)O)CC4)no2)cc1C#N CHEMBL3359847 pEC50 7.943 nM
CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCC(=O)O)CC4)no2)cc1Cl CHEMBL3359846 pEC50 7.943 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CC(=O)O)C4)no2)cc1C#N CHEMBL3359843 pEC50 7.943 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CNC4)no2)cc1Cl CHEMBL3360361 pEC50 7.943 nM
Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C[C@@H](O)CO)C2 CHEMBL3628839 pEC50 7.943 nM
C[C@H](Oc1ccc(-c2nc(-c3ccc4[nH]cnc4c3)no2)cc1C(F)(F)F)C(F)(F)F CHEMBL4297350 pEC50 7.943 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H]4CC[C@@H](CC(=O)O)N4)cc3)no2)cc1 CHEMBL210785 IC50 8.0 nM
NCCCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 CHEMBL1950560 EC50 8.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1ncc(-c2ccc(O[C@H](C)CC)c(C)c2)s1 CHEMBL2022911 EC50 8.0 nM
Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)c2)c(=O)c2ccc(CCO)cc21 CHEMBL2037124 EC50 8.0 nM
C/C(=N\OCc1ccc(-c2ccccc2F)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 CHEMBL2336079 EC50 8.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccccc2)nc2ccc(C(F)(F)F)cc21 CHEMBL3605532 EC50 8.0 nM
CCc1cc(-c2noc(-c3cc(C)cc(CN(C)C)c3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3798218 EC50 8.0 nM
Fc1ccc(F)c(-c2noc(-c3cnn(-c4ccccc4)c3-c3ccccc3)n2)c1 CHEMBL3698527 Ki 8.0 nM
Cc1ccccc1-c1ccc(-c2nc(-c3ccccc3OC(F)(F)F)no2)cc1C CHEMBL3699112 Ki 8.0 nM
Cc1ccccc1-c1ccc(-c2nc(-c3ccccc3OC(F)(F)F)no2)cc1C(F)(F)F CHEMBL3699125 Ki 8.0 nM
COc1ccccc1-c1noc(-c2ccc(-c3ccccc3C)c(C(F)(F)F)c2)n1 CHEMBL3699129 Ki 8.0 nM
Cc1cc(S(=O)(=O)NCCCC(=O)O)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1086158 Ki 8.0 nM
CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CNCC(=O)O)cc2C)ncn1 CHEMBL3968014 Ki 8.0 nM
COc1ccc(OC)c(-c2noc(CCC3(c4ccccc4)CCCCC3)n2)c1 CHEMBL3918461 IC50 8.1 nM
CC(C)(C)c1ccc(-c2noc(-c3ccc(CN4CC(C(=O)O)C4)cc3)n2)cc1 CHEMBL364899 IC50 8.2 nM
COC(=O)C1CN(Cc2ccc(-n3cc(-c4ccc(OC(C)C)c(Cl)c4)nn3)cc2)C1 CHEMBL5204567 EC50 8.35 nM
CCCCCCCCc1ccc(CCC(N)CCP(=O)(O)O)cc1 CHEMBL325198 IC50 8.4 nM
Cc1cc(S(=O)(=O)Nc2cccc(-c3cc(C)c(C(=O)N(C)[C@@H](CN(C)C)C(=O)O)c(C)c3)c2)c(C)cc1Cl CHEMBL2178811 IC50 8.4 nM
CCc1cc(-c2noc(-c3ccnc(CCC(C)C)c3)n2)cc(C)c1OCC(O)CNC(=O)CO CHEMBL3126606 EC50 8.4 nM
CCCCCCCCc1ccc(CC[C@@H](N)CCP(=O)(O)O)cc1 CHEMBL4095976 IC50 8.4 nM
O=C(O)C1CN(Cc2cc(-c3noc(-c4ccc(Oc5ccccc5)cc4)n3)cs2)C1 CHEMBL1951152 EC50 8.5 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3F)cc2)n1 CHEMBL1951309 EC50 8.5 nM
CCCN(C)Cc1cc(-c2nc(-c3cc(C)c(OC[C@@H](O)CNC(=O)CO)c(CC)c3)no2)cc(C)n1 CHEMBL3798697 EC50 8.5 nM
CCNC(=O)C(O)c1ccc(-c2noc(-c3cnn(-c4ccccc4)c3C(F)(F)F)n2)cc1 CHEMBL3686136 IC50 8.5 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)COP(=O)(O)O)cc1 CHEMBL334038 EC50 8.6 nM
O=C(Nc1ccc2[nH]ncc2c1)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1080864 EC50 9.0 nM
CCCCc1ccccc1Oc1ccc(-c2nc(-c3sc(CN4CC(C(=O)O)C4)cc3CC)no2)cc1 CHEMBL1949690 EC50 9.0 nM
CCCCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CN3CCC(C(=O)O)CC3)cc2)s1 CHEMBL2207780 EC50 9.0 nM
C/C(=N\OCc1ccc(-c2ccccc2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 CHEMBL2336072 EC50 9.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(Cl)cc2)nc2ccc(OC)cc21 CHEMBL3605515 EC50 9.0 nM
CCn1c([C@@H](C)NS(=O)(=O)c2ccc(C#N)cc2)nc2cnc(OC)cc21 CHEMBL3605553 EC50 9.0 nM
Fc1ccc(F)c(-c2noc(-c3cnn(C4CCCCC4)c3-c3ccccc3)n2)c1 CHEMBL3701810 Ki 9.0 nM
CC(C)Cn1ncc(-c2nc(-c3cc(F)ccc3F)no2)c1-c1ccncc1 CHEMBL3701813 Ki 9.0 nM
O=C(O)CCNCc1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 CHEMBL1090423 Ki 9.0 nM
CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CNCCC(=O)O)cc2C)ncn1 CHEMBL3974061 Ki 9.0 nM
NC(CO)(CCc1ccc(-c2coc(-c3ccc(Cl)cc3)n2)cc1)COP(=O)(O)O CHEMBL3341920 EC50 9.1 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1 CHEMBL1090829 IC50 9.4 nM
CCCc1c(-c2nc(-c3ccc(C(O)CN4CCNC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 CHEMBL4553920 IC50 9.4 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OCCF)c(C#N)c2)s1 CHEMBL208875 EC50 9.5 nM
CCc1cc(-c2noc(-c3ccc(N(CC)CC)c(C)n3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3126616 EC50 9.5 nM
CCC/N=C1\S/C(=C\c2ccc(OC[C@H](O)CO)c(Cl)c2)C(=O)N1c1ccccc1C CHEMBL1096146 EC50 9.7 nM
O=C(O)[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4474880 EC50 9.7 nM
O=C(O)C1CN(Cc2ccc(-c3noc(COCC4(c5ccc(Cl)cc5)CCC4)n3)c(F)c2)C1 CHEMBL3676136 IC50 9.72 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(C)(N)COP(O)(O)=S)n2)cc1 CHEMBL364950 EC50 9.8 nM
O=C(O)CCn1ncc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21 CHEMBL1916403 EC50 9.8 nM
Cc1sc(C(=O)CCc2ccc(OCCO)c(Cl)c2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL3103668 EC50 9.8 nM
CC(C)(C(=O)N1CCN(c2noc(-c3cc(F)c(OC[C@@H](N)CO)cc3Cl)n2)CC1)C(F)(F)F CHEMBL3344413 EC50 9.8 nM
COCc1c(-c2nc(-c3ccc(C(=O)NCCC(=O)O)cc3)no2)cnn1C1CCCCC1 CHEMBL3701838 Ki 9.9 nM
COc1ccncc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(C(F)(F)F)c1 CHEMBL1938952 EC50 9.999 nM