CCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C)cn2)cc(Cl)n1 CHEMBL4874736 IC50 0.032 nM
CCOc1nc(Cl)cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)c1C CHEMBL4858923 fIC50 0.16 nM
CCOc1nc(C#N)cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)c1C CHEMBL4877484 fIC50 0.19 nM
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O CHEMBL225155 IC50 0.23 nM
Cc1cc(CNC(=O)Nc2cc(Cl)cc(Cl)c2)ncc1-c1cn(C)nc1C CHEMBL4864274 IC50 0.3 nM
Cc1cc(CNc2nc3cc(Cl)c(Cl)cc3[nH]2)ncc1-c1cn(C)nc1C CHEMBL4877932 IC50 0.43 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCN(CC4CCCCC4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5172220 Kd 0.49 nM
CCOc1nc(C)cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)c1Cl CHEMBL4847407 fIC50 0.55 nM
CCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)cc(C(F)(F)F)n1 CHEMBL4867946 fIC50 0.6 nM
Cc1cc(CNC(=O)c2cc3c(Cl)cc(Cl)cc3[nH]2)ncc1-c1cn(C)nc1C CHEMBL4850513 IC50 0.61 nM
CCC(CC)CNC1CCN(C(=O)Nc2cc(Oc3ccncc3)cc(Oc3ccc(F)cc3)c2)CC1 CHEMBL5193759 Kd 0.63 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)N4CCN(C)CC4)cc3)c2)CC1 CHEMBL5206290 Kd 0.69 nM
CCCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL118860 IC50 0.7 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)NC)cc3)c2)CC1 CHEMBL5208524 Kd 0.73 nM
CCCCCCCCc1ccc(CCC(N)(CO)COP(=O)(O)O)cc1 CHEMBL114606 IC50 0.77 nM
Cc1cc(CNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1-c1cn(C)nc1C CHEMBL4847056 IC50 0.77 nM
CCCCCCCCc1ccc(CCC(N)(CO)OP(=O)(O)O)cc1 CHEMBL117130 IC50 0.8 nM
CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1C CHEMBL119440 IC50 0.8 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1-c1cn(C)nc1C CHEMBL4852127 IC50 0.8 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)O)cc3)c2)CC1 CHEMBL5181599 Kd 0.88 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccncc3)cc(Oc3ccc(F)cc3)c2)CC1 CHEMBL5206026 Kd 0.89 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccncc3)cc(Oc3ccc(F)cc3)c2)CC1 CHEMBL3401388 Kd 0.98 nM
CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1Cl CHEMBL119116 IC50 1.0 nM
CCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)cc(Cl)n1 CHEMBL4871481 fIC50 1.0 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCN(C(=O)OC(C)(C)C)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5201190 Kd 1.15 nM
Cc1cc(CNC(=O)c2cc3c(Cl)nc(Cl)cc3[nH]2)ncc1-c1cn(C)nc1C CHEMBL4874151 IC50 1.3 nM
Cc1cc(CNC(=O)Nc2cc(Cl)nc(OCC(F)F)c2)nnc1-c1cn(C)nc1C(F)(F)F CHEMBL4861377 fIC50 1.3 nM
CCOc1nc(C)cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)c1C CHEMBL4853790 fIC50 1.3 nM
CC(C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5076031 IC50 1.3 nM
CCCCCCCn1nnc(-c2ccc(CNCCCP(=O)(O)O)cc2)n1 CHEMBL119382 IC50 1.4 nM
CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL441826 IC50 1.5 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Cl CHEMBL119413 IC50 1.7 nM
CCCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL333335 IC50 1.7 nM
CCCCCCCCc1ccc(CCC(N)COP(=O)(O)O)cc1 CHEMBL432067 IC50 1.8 nM
CCCCCCCc1nc(-c2ccc(CNCCCP(=O)(O)O)cc2)no1 CHEMBL323617 IC50 1.8 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C CHEMBL331054 IC50 1.8 nM
CCCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL118815 IC50 1.9 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1F CHEMBL119873 IC50 2.0 nM
CCOC(=O)c1cc(C)cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)n1 CHEMBL4860509 IC50 2.1 nM
C[C@H](C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5082556 IC50 2.1 nM
CCOc1nc(Cl)cc2nc(NCc3cc(C)c(-c4cn(C)nc4C)cn3)[nH]c12 CHEMBL4868016 IC50 2.25 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)(C)C(=O)O)cc3)c2)CC1 CHEMBL3703203 IC50 2.3 nM
CCCCCCc1ccc(-c2ccc(CNCCCP(=O)(O)O)cc2)cc1 CHEMBL116981 IC50 2.6 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)Nc3ccc(O)cc3)c(=O)c3ccccc32)cc1Cl CHEMBL5192525 IC50 2.6 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Br CHEMBL119354 IC50 2.9 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br CHEMBL332667 IC50 3.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)NC)cc3)c2)CC1 CHEMBL3401386 IC50 3.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C4(C(=O)O)CC4)cc3)c2)CC1 CHEMBL3703198 IC50 3.0 nM
CCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)cc(C#N)n1 CHEMBL4860157 fIC50 3.0 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc(-c2cnn(C)c2)c1 CHEMBL4877928 IC50 3.1 nM
C[C@H](C(=O)O)n1nc(Cn2cc3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5079623 IC50 3.2 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(C(=O)Oc3ccc(C(C)(C)C(=O)O)cc3)c2)CC1 CHEMBL3703202 IC50 3.4 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1-c1cnn(C)c1 CHEMBL4867313 IC50 3.4 nM
CC(C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(C(F)(F)F)cc3n2)c2ccccc2c1=O CHEMBL5090966 IC50 3.4 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)O)c(Cl)c3)c2)CC1 CHEMBL3759037 IC50 3.6 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(N)=O)cc3)c2)CC1 CHEMBL3401383 IC50 3.7 nM
CCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117910 IC50 3.9 nM
CCCCCCCCC(=O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL115970 IC50 4.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)O)cc3)c2)CC1 CHEMBL3758929 IC50 4.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(S(N)(=O)=O)cc3)c2)CC1 CHEMBL3401382 IC50 4.1 nM
COc1ccc(NC(=O)Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc([123I])c(OC)cc3OC)c2=O)cc1 CHEMBL5190929 Kd 4.31 nM
CCCCCCCCc1ccc(CC[C@@H](N)C[C@@H](O)P(=O)(O)O)cc1 CHEMBL115554 IC50 4.5 nM
CCCCCCCCc1ccc(CC[C@@H](N)C[C@H](O)P(=O)(O)O)cc1 CHEMBL115713 IC50 4.5 nM
O=C(O)Cc1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5078844 IC50 4.8 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)Nc3ccccc3O)c(=O)c3ccccc32)cc1Cl CHEMBL5199972 IC50 4.8 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)N4CCCC(O)C4)cc3)c2)CC1 CHEMBL3703200 IC50 5.1 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(c4ccc(Cl)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5199565 Kd 5.16 nM
CC(C)CC1(O)CN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)(C)C(=O)O)cc3)c2)C1 CHEMBL3703201 IC50 5.2 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1N(C)C CHEMBL4871414 IC50 5.3 nM
Cc1cc(CNC(=O)Nc2cc(C(F)(F)F)nc(OCCO)c2C)nnc1-c1cn(C)nc1C(F)(F)F CHEMBL4866666 fIC50 5.4 nM
CCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL119256 IC50 5.5 nM
CCC(C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5073747 IC50 5.6 nM
COc1ccc(NC(=O)Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc(Cl)c(OC)cc3OC)c2=O)cc1 CHEMBL5184379 IC50 5.7 nM
CCCCCCCCc1ccc(CC[C@](N)(CO)COP(=O)(O)O)cc1 CHEMBL366208 IC50 5.9 nM
CCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL118783 IC50 6.1 nM
CCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL325247 IC50 6.2 nM
O=C(O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(c4ccc(F)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3618201 IC50 6.2 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc(-c2ccc(F)cc2)c1 CHEMBL4873481 IC50 6.2 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL332373 IC50 6.3 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)Nc3ccccc3OC)c(=O)c3ccccc32)cc1Cl CHEMBL5200959 IC50 6.3 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C4(C(=O)O)CC4)cc3)c2)CC1 CHEMBL3759864 IC50 6.4 nM
O=C(O)Cn1nc(Cc2nc3cc(C(F)(F)F)c(OCC4CC4)cc3[nH]2)c2ccccc2c1=O CHEMBL5081728 IC50 6.6 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)N(C)C)cc3)c2)CC1 CHEMBL3401387 Kd 6.62 nM
CCNC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(CC(CC)CC)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3703199 IC50 7.0 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1C#N CHEMBL4845863 IC50 7.0 nM
CCNC(=O)c1ccc(Oc2cc(NC(=O)N3CCN(CC(CC)CC)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5197668 Kd 7.23 nM
O=C(Nc1cc(Oc2ccc(F)cc2)cc(Oc2ccc(F)cc2)c1)Nc1cc(Cl)nc(Cl)c1 CHEMBL5176095 Kd 7.48 nM
O=C(O)Cn1nc(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5070413 IC50 7.6 nM
CC(C)(C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5093130 IC50 7.7 nM
CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117715 IC50 8.0 nM
O=C(O)Cn1nc(Cn2cc3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5079608 IC50 8.1 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)(C)C(=O)O)cc3)c2)C1 CHEMBL3759434 IC50 8.2 nM
O=C(Nc1cc(Oc2ccncc2)cc(Oc2ccc(F)cc2)c1)Nc1cc(Cl)nc(Cl)c1 CHEMBL5182489 Kd 8.76 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3cccc(C(C)(C)C(=O)O)c3)c2)CC1 CHEMBL3758872 IC50 8.8 nM
CC(C)(C(=O)O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(C4CCCC4)C3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3759532 IC50 8.8 nM
O=C(O)Cn1nc(Cc2nc3cc(Cl)c(OCC4CC4)cc3[nH]2)c2ccccc2c1=O CHEMBL5076737 IC50 8.8 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)C(=O)O)cc3)c2)CC1 CHEMBL3758775 IC50 9.3 nM
Cc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)ncc1-c1ccn(C)n1 CHEMBL4864744 IC50 9.3 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)Nc3cc(Cl)nc(Cl)c3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5181338 Kd 9.44 nM
Cc1nn(C)c2nc(NNC(=O)C(C)c3cc(Cl)nc(O[11CH3])c3)cc(C(C)C)c12 CHEMBL5186556 IC50 9.52 nM
CCCCCCCCc1ccc(CCC(N)CC(O)P(=O)(O)O)cc1 CHEMBL113344 IC50 9.8 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117723 IC50 10.0 nM
Cc1nn(C)c2nc(NNC(=O)Nc3cc(Cl)nc(Cl)c3)cc(C(C)C)c12 CHEMBL1368758 IC50 10.0 nM
CCOc1cc2[nH]c(Cc3nn(CC(=O)N4CCOCC4)c(=O)c4ccccc34)nc2cc1Cl CHEMBL5091304 IC50 10.0 nM
CCCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL117973 IC50 11.0 nM
COc1cc(Oc2cc(NC(=O)N3CCC(O)(CC(C)C)CC3)cc(Oc3ccc(F)cc3)c2)ccc1C(=O)O CHEMBL3758974 IC50 11.0 nM
CCCCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL115738 IC50 12.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1OCC CHEMBL324820 IC50 12.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)O)cc3)c2)CC1 CHEMBL3758214 IC50 12.0 nM
O=C(O)Cn1nc(Cc2nc3cc(Cl)c(OCC(F)F)cc3[nH]2)c2ccccc2c1=O CHEMBL5091947 IC50 12.0 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)NC4CCCCC4)cc3)c2)CC1 CHEMBL5173580 Kd 12.65 nM
CCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL334213 IC50 13.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3cccc(C(N)=O)c3)c2)CC1 CHEMBL3401384 IC50 13.0 nM
O=C(Nc1cc(Cl)nc(Cl)c1)Nc1cc(Cl)nc(Cl)c1 CHEMBL4871603 Kd 13.2 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Sc3ccc(S(C)(=O)=O)cc3)c2)CC1 CHEMBL4461033 IC50 14.6 nM
CCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)cc(C)n1 CHEMBL4878889 fIC50 15.0 nM
O=C(O)C1(c2nn(Cc3cn4cc(OCC5CC5)c(Cl)cc4n3)c3ccccc3c2=O)CC1 CHEMBL5094625 IC50 16.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)O)cc3F)c2)CC1 CHEMBL3759799 IC50 17.0 nM
CC(C)(C(=O)O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(C4CCCCC4)C3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3758803 IC50 17.0 nM
CCOc1cc2[nH]c(Cc3nn(CC(=O)O)c(=O)c4ccccc34)nc2cc1Cl CHEMBL5088734 IC50 17.0 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(N)(CO)COP(=O)(O)O)n2)cc1 CHEMBL537849 EC50 18.0 nM
O=C(O)Cn1nc(Cc2nc3cc(F)c(OCC4CC4)cc3[nH]2)c2ccccc2c1=O CHEMBL5077930 IC50 18.0 nM
CCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL119562 IC50 19.0 nM
CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL432813 IC50 19.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(C(=O)O)cc3)cc(Oc3ccc(F)cc3F)c2)CC1 CHEMBL3759551 IC50 20.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(CC(=O)O)cc3)c2)CC1 CHEMBL3759492 IC50 21.0 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCN(c4ccc(OC)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5206287 Kd 21.54 nM
CCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)cn2)cc(Cl)n1 CHEMBL4845783 IC50 22.0 nM
COC(C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5081161 IC50 23.0 nM
CCOc1cc2cn(Cc3nn(CC(=O)O)c(=O)c4ccccc34)nc2cc1Cl CHEMBL5088730 IC50 23.0 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1OC CHEMBL118508 IC50 24.0 nM
C[C@@H](C(=O)O)c1nn(Cc2cn3cc(OCC4CC4)c(Cl)cc3n2)c2ccccc2c1=O CHEMBL5084509 IC50 24.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(C(=O)O)cc3)cc(Oc3ccc(F)c(F)c3)c2)CC1 CHEMBL3758346 IC50 25.0 nM
CCCCCCCCc1ccc(CC[C@H](N)C[C@@H](O)P(=O)(O)O)cc1 CHEMBL114976 IC50 27.0 nM
CC(C)C1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)(C)C(=O)O)cc3)c2)C1 CHEMBL3760061 IC50 29.0 nM
Cc1nn(C)c2nc(NNC(=O)Nc3cc(Cl)nc(OC(C)C)c3)cc(C(C)C)c12 CHEMBL4204756 IC50 29.1 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCN(C(=O)c4ccc5ccccc5c4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5184083 Kd 29.21 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc4c(c3)CCNC4=O)c2)CC1 CHEMBL4462730 IC50 29.9 nM
O=C(Cc1nn(CC(=O)N2CCOCC2)c(=O)c2ccccc12)Nc1ccc(OC(F)(F)F)c(Cl)c1 CHEMBL5087855 IC50 30.0 nM
Cc1cc(CO)nc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)c1 CHEMBL4870007 IC50 31.0 nM
O=C(O)Cn1nc(Cc2nc3cc(Cl)c(OC(F)(F)F)cc3[nH]2)c2ccccc2c1=O CHEMBL5074164 IC50 31.0 nM
COc1cc(OC)c(NC(=O)Cc2nn(CC(=O)O)c(=O)c3ccccc23)cc1Cl CHEMBL5076177 IC50 32.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)O)c(F)c3)c2)CC1 CHEMBL3759218 IC50 34.0 nM
Cn1ncc2c(-c3ccc(F)cc3)cc(NNC(=O)Nc3cc(Cl)nc(Cl)c3)nc21 CHEMBL5175095 Kd 34.8 nM
CCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL118265 IC50 38.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Sc3ccc(S(C)(=O)=O)cc3)c2)CC1 CHEMBL4539520 IC50 38.5 nM
CS(=O)(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(c4ccc(F)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3618199 IC50 39.0 nM
NS(=O)(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(c4ccc(F)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3618200 IC50 39.0 nM
COc1cccc(NC(=O)Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc(Cl)c(OC)cc3OC)c2=O)c1 CHEMBL5178835 IC50 39.1 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)NCCO)c(=O)c3ccccc32)cc1Cl CHEMBL5184621 IC50 40.1 nM
CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1O CHEMBL119239 IC50 41.0 nM
CCCCCCCCNc1ncnc2ccccc12 CHEMBL1563943 IC50 41.97 nM
CCCCCCCc1ccc(CCCNCCCP(=O)(O)O)cc1 CHEMBL119233 IC50 42.0 nM
O=C(Cc1nn(C2CCNC2)c(=O)c2ccccc12)Nc1ccc(OC(F)(F)F)c(Cl)c1 CHEMBL5086993 IC50 42.0 nM
CCCCCCCCc1ccc(CCNCCCP(=O)(O)O)cc1 CHEMBL325193 IC50 45.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(S(C)(=O)=O)cc3)c2)CC1 CHEMBL3401381 IC50 45.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccccc3C(N)=O)c2)CC1 CHEMBL3401385 IC50 49.0 nM
CCOc1ccc(C(=O)Cn2c(=O)n(CC(=O)Nc3ccccc3OC)c(=O)c3ccccc32)cc1Cl CHEMBL5199020 IC50 49.8 nM
COc1ccccc1NC(=O)Cn1c(=O)c2ccccc2n(CC(=O)Nc2cc(Cl)ccc2OC)c1=O CHEMBL5180516 IC50 54.9 nM
CCOc1cc(NC(=O)NCc2cc(C)c(Nc3cn(C)nc3C)cn2)cc(C(F)(F)F)n1 CHEMBL4869752 IC50 55.0 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)N(C)C)cc3)c2)CC1 CHEMBL5174563 Kd 55.62 nM
Cc1nn(C)c2nc(NNC(=O)Nc3cc(Cl)nc(OCC4CC4)c3)cc(C(C)C)c12 CHEMBL4212397 IC50 56.5 nM
CCCCCCCCCc1ccc(CNCC(F)CC(=O)O)cc1 CHEMBL424254 IC50 57.0 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)NCCc3cccnc3)c(=O)c3ccccc32)cc1Cl CHEMBL5199083 IC50 58.7 nM
O=P(O)(O)CCCNCCCCCCCCCCc1ccccc1 CHEMBL119349 IC50 59.0 nM
CCCCCCCCCc1ccc(CNCCCP(C)(=O)O)cc1 CHEMBL432809 IC50 60.0 nM
COc1cc2[nH]c(Cc3nn(CC(=O)O)c(=O)c4ccccc34)nc2cc1Cl CHEMBL5087518 IC50 61.0 nM
CCN1/C(=C\C=C\C2=[N+](CC)c3ccccc3C2(C)C)C(C)(C)c2ccccc21 CHEMBL1518905 IC50 64.0 nM
CCCCCCCCCc1ccc(CNCC(O)CC(=O)O)cc1 CHEMBL116140 IC50 66.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)NCCF)cc3)c2)CC1 CHEMBL4565410 IC50 66.7 nM
O=C(Nc1cc(Oc2ccncc2)cc(Oc2ccc(F)cc2)c1)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL5187883 Kd 66.92 nM
CCCCCCCCc1ccc(CC[C@H](N)C[C@H](O)P(=O)(O)O)cc1 CHEMBL115714 IC50 73.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc4c(c3)CCN(C)C4=O)c2)CC1 CHEMBL4446353 IC50 73.3 nM
CCCCCCCCc1ccc(CCC(N)/C=C/P(=O)(O)O)cc1 CHEMBL91283 IC50 76.0 nM
NC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(c4ccc(F)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3618197 IC50 76.0 nM
NC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(c4ccc(Cl)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL3618196 IC50 83.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C#N)cc3)c2)CC1 CHEMBL3401380 IC50 84.0 nM
CCCCCCCCCCCCCC(N)CCP(=O)(O)O CHEMBL119760 IC50 86.0 nM
CCCCCCCCCCCCC(N)CCP(=O)(O)O CHEMBL421234 IC50 86.0 nM
Cc1cc(CNC(=O)Nc2cc(OCCO)nc(C(F)(F)F)c2)nnc1-c1cn(C)nc1C(F)(F)F CHEMBL4860408 fIC50 87.0 nM
CCC(CC)CN1CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(N)=O)cc3)c2)CC1 CHEMBL5199950 Kd 88.5 nM
N#CC(c1cccc(Cl)c1)c1ccc2c(C(F)(F)F)cc(C(F)(F)F)nc2n1 CHEMBL533602 IC50 90.0 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)NCCOCCO)c(=O)c3ccccc32)cc1Cl CHEMBL5176528 IC50 91.4 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCN(C(=O)c4ccc(F)cc4)CC3)cc(Oc3ccc(F)cc3)c2)cc1 CHEMBL5192337 Kd 94.34 nM
CCCCCCCCCc1ccc(CNCCC(O)C(=O)O)cc1 CHEMBL118068 IC50 99.0 nM
CCCCCCCCc1ccc(CCC(N)CCP(=O)(O)O)cc1 CHEMBL325198 IC50 100.0 nM
O=C(NC(Nc1nc2ccc([N+](=O)[O-])cc2s1)(C(F)(F)F)C(F)(F)F)c1ccccc1 CHEMBL1504701 IC50 101.0 nM
CCOc1cc(NC(=O)NCc2cc(C)c(N3CC(C)OC(C)C3)cn2)cc(Cl)n1 CHEMBL4858509 IC50 105.0 nM
NC(CCCCCCCCCCc1ccccc1)CCP(=O)(O)O CHEMBL117031 IC50 110.0 nM
CCCCCCCCC(O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL117007 IC50 110.0 nM
CCOc1cc2nn(Cc3nn(CC(=O)O)c(=O)c4ccccc34)cc2cc1Cl CHEMBL5088495 IC50 113.0 nM
O=C(Nc1cc(Oc2ccncc2)cc(Oc2ccc(F)cc2)c1)N1CCC(O)(c2ccc(F)cc2)CC1 CHEMBL3618198 IC50 123.0 nM
CCCCCCCCCc1ccc(CNCCCP(O)O)cc1 CHEMBL1160958 IC50 140.0 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)N(C)C)c(=O)c3ccccc32)cc1Cl CHEMBL5177583 IC50 175.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(OC)cc3)c2)CC1 CHEMBL4459775 IC50 188.5 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)NCCF)cc3)c2)CC1 CHEMBL4542538 IC50 194.5 nM
CCn1nc(CC(=O)Nc2ccc(OC(F)(F)F)c(Cl)c2)c2ccccc2c1=O CHEMBL5080142 IC50 199.0 nM
CCCCCCCCCc1ccc(CNCCC(F)(F)C(=O)O)cc1 CHEMBL119516 IC50 200.0 nM
CCCCCCCCCc1ccc(CNCCCC(=O)O)cc1 CHEMBL432632 IC50 200.0 nM
COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)NCCOCCOCCO)c(=O)c3ccccc32)cc1Cl CHEMBL5177879 IC50 204.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3cccnc3)c2)CC1 CHEMBL3401389 IC50 210.0 nM
O=C(Cc1nn(C2CC2)c(=O)c2ccccc12)Nc1ccc(OC(F)(F)F)c(Cl)c1 CHEMBL5074979 IC50 218.0 nM
CCCCCCCCc1ccc(CCC(N)(CO)CCP(=O)(O)O)cc1 CHEMBL114584 IC50 230.0 nM
CCCCCCCCc1ccc(CCC(N)C(O)CP(=O)(O)O)cc1 CHEMBL112655 IC50 240.0 nM
CCCCCCCCCCCCCC1CCCC(CCP(C)(=O)O)N1 CHEMBL187692 IC50 250.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccccn3)c2)CC1 CHEMBL3401390 IC50 260.0 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)CCP(=O)(O)O)cc1 CHEMBL228139 EC50 270.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(C(F)(F)F)c2)CC1 CHEMBL4592049 IC50 270.3 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(C(=O)NC)cc3)cc(C(F)(F)F)c2)CC1 CHEMBL4466980 IC50 278.5 nM
COc1ccc(C(=O)Cn2c(=O)n(CC(=O)Nc3ccccc3OC)c(=O)c3ccccc32)cc1Cl CHEMBL5205671 IC50 287.0 nM
CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(C(F)(F)F)c2)CC1 CHEMBL4533520 IC50 296.5 nM
CCCCCCCCCCCCCC[C@H]1CC[C@H](CCP(=O)(O)O)N1 CHEMBL187588 IC50 330.0 nM
CCCCCCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 CHEMBL1481347 IC50 333.0 nM
CN(C)CCCNS(=O)(=O)c1ccc(N2CCC(c3ccc(Cl)cc3)=N2)cc1 CHEMBL1530797 EC50 338.0 nM
CNC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(CC(C)C)CC3)cc(C(F)(F)F)c2)cc1 CHEMBL4446396 IC50 359.3 nM
Cc1cc(/C=N/n2cnnc2)c(C)n1-c1ccc(OCc2ccc(Cl)cc2)cc1 CHEMBL1985061 IC50 362.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(C(F)(F)F)c2)CC1 CHEMBL4437497 IC50 362.3 nM
CNC(=O)Cn1c(=O)c2ccccc2n(CC(=O)Nc2cc(Cl)c(OC)cc2OC)c1=O CHEMBL5205389 IC50 376.0 nM
O=C(O)Cn1nc(CC(=O)Nc2ccc(OC(F)(F)F)c(Cl)c2)c2ccccc2c1=O CHEMBL5093933 IC50 389.0 nM
CCCCCCCCCc1ccc(C2CCC(CCP(=O)(O)O)N2)cc1 CHEMBL184879 IC50 422.0 nM
CCCCCCCCCCCCCCCC(N)CCP(=O)(O)O CHEMBL334144 IC50 450.0 nM
CCCCCCCCCn1c2c(c(=N)c3c1CCC3)CCC2 CHEMBL1596681 IC50 459.0 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)CC(F)OP(=O)(O)O)cc1 CHEMBL226612 EC50 490.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(C)cc(Oc3ccc(F)cc3)c2)CC1 CHEMBL3401376 IC50 500.0 nM
COc1ccc(-c2cc(NNC(=O)Nc3cc(Cl)nc(Cl)c3)nc3c2cnn3C)cc1 CHEMBL5206542 Kd 520.0 nM
CCCCCCc1ccc(OC[C@H](N)CCP(=O)(O)O)cc1 CHEMBL228049 EC50 530.0 nM
Cc1ccc2[nH]c3c(N4CCc5ccccc5C4)ncnc3c2c1 CHEMBL1347469 IC50 569.0 nM
CCCCCCCc1ccc(CCCCNCCCP(=O)(O)O)cc1 CHEMBL119257 IC50 590.0 nM
COC(=O)C1CN(C#N)N(c2ccc(Cl)cc2)C12c1ccccc1-c1ccccc12 CHEMBL1540682 IC50 607.0 nM
CCOC(=O)/C(=C\c1ccc(OC(F)F)cc1)C1=Nn2c(nnc2-c2ccc(Cl)cc2)SC1 CHEMBL1412583 IC50 614.2 nM
Cn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1334062 IC50 634.0 nM
COc1ccc(OC)c(NC(=O)CSc2ncnc3c2cnn3-c2ccccc2Cl)c1 CHEMBL1413625 IC50 640.0 nM
COCCOc1cc(NC(=O)NCc2cc(C)c(-c3cn(C)nc3C(F)(F)F)nn2)cc(Cl)n1 CHEMBL4859853 IC50 640.0 nM
CCCCCCCOC(=O)c1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL117403 IC50 680.0 nM
CCN1/C(=C/c2ccc3cccc(C)c3[n+]2CC)Sc2ccccc21 CHEMBL1404792 IC50 686.0 nM
Cc1cc(C(=O)Cn2cc(C(F)(F)F)ccc2=O)c(C)n1Cc1ccccc1 CHEMBL1359777 EC50 723.0 nM
COc1ccc(NC(=O)/C(Cl)=C(/Cl)[S+]([O-])Cc2ccc(C)cc2)cn1 CHEMBL1344225 IC50 752.0 nM
O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1ccc(CN2CCc3ccccc3C2)cc1 CHEMBL1411912 IC50 773.0 nM
CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2c1cnn2C CHEMBL5192020 Kd 780.0 nM
O=C(c1cc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc(NC(=O)C23CC4CC(CC(C4)C2)C3)c1)N1CCCCC1 CHEMBL1309450 IC50 793.0 nM
Fc1ccc2[nH]c3c(N4CCN(Cc5ccc6c(c5)OCO6)CC4)ncnc3c2c1 CHEMBL1304582 IC50 810.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(C)cc(Oc3ccccc3)c2)CC1 CHEMBL3401373 IC50 820.0 nM
CCCCCCCCCCCCCCC(N)CCP(=O)(O)O CHEMBL119110 IC50 830.0 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Cl)cc(Oc3ccc(F)cc3)c2)CC1 CHEMBL3401377 IC50 860.0 nM
Cc1c(Cc2ccccc2)c(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2c1cnn2C CHEMBL5209490 Kd 870.0 nM
CCOC(=O)N1CCN(C(=O)CSCC(=O)Nc2nc(-c3ccc(-c4ccccc4)cc3)cs2)CC1 CHEMBL1470979 IC50 873.0 nM
NS(=O)(=O)c1ccc(N2N=C(c3ccc(Br)cc3)CC2c2ccc(F)cc2)cc1 CHEMBL1447076 EC50 877.0 nM
CCCc1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2c1c(C(F)(F)F)nn2C CHEMBL5195317 Kd 890.0 nM
Cn1nc(C(F)(F)F)c2c(-c3ccccc3)cc(NNC(=O)Nc3cc(Cl)nc(Cl)c3)nc21 CHEMBL5172385 Kd 940.0 nM
COc1ccc(NC(=O)/C(Cl)=C(/Cl)[S+]([O-])Cc2ccccc2)cn1 CHEMBL1574879 IC50 942.0 nM
CCCCCCCCCCCCNC(=O)[C@@H](N)COP(=O)(O)O CHEMBL324358 EC50 973.2 nM
CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(F)cc3)c2)CC1 CHEMBL3401379 IC50 980.0 nM
Cc1nn(C)c2nc(NNC(=O)Nc3cc(Cl)nc(Cl)c3)cc(-c3ccc(F)cc3)c12 CHEMBL5205630 Kd 980.0 nM
CCCCCCCCc1ccc(CCC(N)CCC(=O)O)cc1 CHEMBL325050 IC50 1000.0 nM