Cc1cc(OC2CCC3(CCCC3)CC2)c(CN2CCC(C(=O)O)CC2)c2ccccc12 CHEMBL4787458 EC50 0.03 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CNC2CC(C(=O)O)C2)c2ccccc12 CHEMBL4754965 EC50 0.063 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CN2CCC(C(=O)O)CC2)c2ccccc12 CHEMBL4748198 EC50 0.1 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CNCCC(=O)O)c2ccccc12 CHEMBL4798593 EC50 0.1 nM
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O CHEMBL225155 EC50 0.2 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CNC2CCC(C(=O)O)CC2)c2ccccc12 CHEMBL4784199 EC50 0.27 nM
CCCCCCCCc1ccc(CC[C@](N)(CO)COP(=O)(O)O)cc1 CHEMBL366208 EC50 0.3 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(CCC(F)(F)F)cc4)n3)cc2)C1 CHEMBL381872 IC50 0.3 nM
CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1 CHEMBL314854 EC50 0.3 nM
CCCCCCCCc1ccc2c(c1)CC[C@@H](C(N)(CO)COP(=O)(O)O)C2 CHEMBL1091103 EC50 0.33 nM
CCCc1ccc(COc2ccc3c(c2)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)c1 CHEMBL4093489 EC50 0.33 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc([C@@H]5CCC(F)(F)C5)cc4)n3)cc2)C1 CHEMBL195014 IC50 0.4 nM
CCCCCCCCc1ccc(CCC(N)(CO)COP(=O)(O)O)cc1 CHEMBL114606 EC50 0.4 nM
CCCCCCCCc1ccc(CC[C@@](N)(CO)COP(=O)(O)O)cc1 CHEMBL190006 EC50 0.46 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCCC5)cc4)n3)cc2)C1 CHEMBL198976 IC50 0.5 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc([C@H]5CCC(F)(F)C5)cc4)n3)cc2)C1 CHEMBL198415 IC50 0.5 nM
O=C(O)C[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4458575 EC50 0.53 nM
CCCCCCCCCc1ccc(C2CCC(CCP(=O)(O)O)N2)cc1 CHEMBL184879 IC50 0.58 nM
Cc1cc(CN2CC(C(=O)O)C2)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1083828 EC50 0.6 nM
CCCCCCCCOc1ccc(-c2nnc([C@@](C)(N)COP(=O)(O)O)s2)cc1C(F)(F)F CHEMBL3102904 EC50 0.66 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C(F)(F)F)C(F)(F)F)c(C#N)c2)n1 CHEMBL210942 EC50 0.7 nM
CCCCCCCCc1ccc(CCC(N)(CO)CO[PH](O)(O)O)cc1 CHEMBL1161691 IC50 0.77 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCCCC5)cc4)n3)cc2)C1 CHEMBL196534 IC50 0.8 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CNC2CCC(C(=O)O)C2)c2ccccc12 CHEMBL4747262 EC50 0.81 nM
CCCc1ccc(COc2ccc3c(c2C)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)n1 CHEMBL4087932 EC50 0.92 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CN2CCC(C(=O)O)C2)c2ccccc12 CHEMBL4798181 EC50 0.96 nM
CCc1cc(/C(C)=N/OCc2ccc(C3CCCCC3)c(C(F)(F)F)c2)ccc1CN1CC(C(=O)O)C1 CHEMBL2336071 EC50 0.98 nM
CCCc1ccc(COc2ccc3c(c2C)CCC(CN2CC(C(=O)O)C2)=C3C)c(OC)c1 CHEMBL4095920 EC50 0.98 nM
CCCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL193789 IC50 1.0 nM
CC(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL194419 IC50 1.0 nM
CCCCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3739440 IC50 1.0 nM
O=C(O)C1CN(Cc2ccc(CCc3cccc(C(F)(F)F)c3)cc2)C1 CHEMBL1973936 IC50 1.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cccc(C(F)(F)F)c3)c(Cl)c2)C1 CHEMBL3741092 IC50 1.0 nM
Cc1cc(OCc2cccc(C(F)(F)F)c2)ccc1CN1CC(C(=O)O)C1 CHEMBL1966501 IC50 1.0 nM
Cc1cc(OCc2ccc(Cl)c(Cl)c2)ccc1CN1CC(C(=O)O)C1 CHEMBL1990223 IC50 1.0 nM
CC(C)Oc1ccc(COc2ccc3c(c2)CCC3N2CC(C(=O)O)C2)cc1C(F)(F)F CHEMBL5407282 EC 1.0 nM
O=C(O)C1CN(C2CCc3cc(OCc4ccc(C5CC5)c(C(F)(F)F)c4)ccc32)C1 CHEMBL5421290 EC 1.0 nM
O=C(O)C1CN(C2CCc3cc(OCc4cc(F)c(F)cc4F)ccc32)C1 CHEMBL5427624 EC 1.0 nM
CCCCCCCCOc1ccc(-c2c[nH]c([C@@](C)(N)COP(=O)(O)O)n2)cc1F CHEMBL473269 IC50 1.1 nM
O=C(O)[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1 CHEMBL4448752 EC50 1.1 nM
Cc1cc(OC2CCC3(CCCCC3)CC2)c(CN2CCC(C(=O)O)CC2)c2ccccc12 CHEMBL4757160 EC50 1.1 nM
CCCCCCCCCc1ccc(CN[C@H]2CCC[C@H](P(=O)(O)O)C2)cc1 CHEMBL181597 IC50 1.2 nM
CCCCCCCCOc1ccc(-c2c[nH]c([C@@](C)(N)COP(=O)(O)O)n2)cc1 CHEMBL474689 IC50 1.4 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CNCCCC(=O)O)c2ccccc12 CHEMBL4778095 EC50 1.4 nM
CCCCCCOc1cc(C)c2ccccc2c1CNCCC(=O)O CHEMBL4751484 EC50 1.4 nM
CCCCCCCCc1ccc2c(c1)CC[C@H]([C@@](C)(N)COP(=O)(O)O)C2 CHEMBL1093686 EC50 1.49 nM
CCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL194578 IC50 1.6 nM
CCC(C)(C)c1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL372066 IC50 1.8 nM
CCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)COP(=O)(O)O CHEMBL199791 Log EC50 1.995 nM
CCCCCCCOc1ccc(CC[C@@](C)(N)COP(=O)(O)O)cc1 CHEMBL382739 Log EC50 1.995 nM
C[C@@](N)(CCc1ccc(OCCCCCCCCCCCNc2ccc([N+](=O)[O-])c3nonc23)cc1)COP(=O)(O)O CHEMBL371758 Log EC50 1.995 nM
CCCCCCCCOc1ccc(-c2cnc([C@@](C)(N)COP(=O)(O)O)s2)cc1C(F)(F)F CHEMBL3102903 EC50 2.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cccc(C(F)(F)F)c3)cc2F)C1 CHEMBL1998478 IC50 2.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cccc(C(F)(F)F)c3)c(F)c2)C1 CHEMBL3741572 IC50 2.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cccc(C(F)(F)F)c3)cc2Cl)C1 CHEMBL1986265 IC50 2.0 nM
CCCCCC(=O)c1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3740009 IC50 2.0 nM
CCCCCCCCCc1ccc(CN2CCC(P(=O)(O)O)C2)cc1 CHEMBL184349 IC50 2.2 nM
CCCCCCCOc1ccc(CC[C@](C)(N)COP(=O)(O)O)cc1 CHEMBL1084929 EC50 2.2 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CN2CC(C(=O)O)C2)c2ccccc12 CHEMBL4796939 EC50 2.3 nM
CCc1cccc(Cl)c1CSc1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1 CHEMBL4210019 pEC50 2.512 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCCc2ccccc2)cc1 CHEMBL473156 IC50 2.9 nM
CC(C)CCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3740090 IC50 3.0 nM
CCc1ccc(-c2ccc(CN3CC(C(=O)O)C3)cc2)cc1 CHEMBL3740359 IC50 3.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C(F)(F)F)c(C#N)c2)n1 CHEMBL378436 EC50 3.1 nM
CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)c(F)c1 CHEMBL474688 IC50 3.2 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCCCCc3ccccc3)cc2)c[nH]1 CHEMBL470511 IC50 3.5 nM
COc1ccccc1CC[C@@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL4637401 EC50 3.5 nM
COCCCCC[C@@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL4752394 EC50 3.6 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CN2CCC(CC(=O)O)C2)c2ccccc12 CHEMBL4744455 EC50 3.7 nM
Cc1cc(C(C)CC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL391869 EC50 3.9 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCC5)cc4)n3)cc2)C1 CHEMBL194898 IC50 4.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cccc(C(F)(F)F)c3)cc2)C1 CHEMBL1971132 IC50 4.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccc(Cl)cc3Cl)cc2)C1 CHEMBL1968499 IC50 4.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C1 CHEMBL3741589 EC50 4.1 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCCO)no2)cc1C#N CHEMBL3707247 EC50 4.3 nM
CCOCCC[C@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL4786296 EC50 4.9 nM
CCCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3739878 IC50 5.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)c([N+](=O)[O-])c2)C1 CHEMBL3741022 IC50 5.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2F)C1 CHEMBL3741298 IC50 5.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)c(F)c2)C1 CHEMBL3740093 IC50 5.0 nM
CCCCCCC(=O)c1ccc(CN2CCC(C(=O)O)C2)cc1 CHEMBL3740964 IC50 5.0 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc([C@@H]5CCC(F)(F)C5)cc4)n3)cc2)C1 CHEMBL208838 IC50 5.1 nM
Cc1cc([C@@H]2C[C@H]2C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL391870 EC50 5.1 nM
CC(C)(C)c1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL195141 IC50 5.2 nM
Cc1cc([C@@H]2C[C@H]2C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL391581 EC50 5.2 nM
CCCCCCCCc1ccc([C@@H]2C[C@@H](COP(=O)(O)O)N[C@H]2CO)cc1 CHEMBL247699 EC50 5.8 nM
O=C(O)CC1NCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3403619 EC50 5.8 nM
O=C(O)C1CN(Cc2ccc(OCc3ccccc3)cc2Cl)C1 CHEMBL1987998 IC50 6.0 nM
O=C(O)CCNCc1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 CHEMBL1090423 EC50 6.3 nM
O=C(O)CCN1CCC2(CC1)COc1c2ccc(OCc2c(Cl)cccc2Cl)c1F CHEMBL4208771 pEC50 6.31 nM
CCCCCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL371670 IC50 6.4 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL211505 EC50 6.5 nM
CCCCCCCCc1ccc2[nH]c([C@@H](N)COP(=O)(O)O)nc2c1 CHEMBL185491 EC50 6.6 nM
CC(C)(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL366181 IC50 6.6 nM
CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)cc1F CHEMBL515921 IC50 6.9 nM
Cc1ccc(-c2ccc(CN3CC(C(=O)O)C3)cc2)cc1 CHEMBL3742384 IC50 7.0 nM
CCCCCCC(=O)c1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3739887 IC50 7.0 nM
Cc1cc(Cl)c(COc2ccc3c(c2)OCC32CCN(CCC(=O)O)CC2)c(Cl)c1 CHEMBL4213167 pEC50 7.943 nM
Cc1cc(OCc2ccccc2)ccc1CN1CC(C(=O)O)C1 CHEMBL3742033 IC50 8.0 nM
O=C(Cc1ccc(Cl)c(Cl)c1)c1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3741988 IC50 8.0 nM
O=C(Cc1ccc(Cl)c(Cl)c1)c1ccc(CN2CCC(C(=O)O)C2)cc1 CHEMBL3740180 IC50 8.0 nM
CCCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 CHEMBL118860 IC50 8.2 nM
CCCCCCCCc1ccc2[nH]c([C@H](N)COP(=O)(O)O)nc2c1 CHEMBL361915 EC50 8.2 nM
CCCCCCCCc1ccc2nc([C@@H](N)COP(=O)(O)O)[nH]c2c1 CHEMBL1910653 EC50 8.2 nM
CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(=O)(O)O)cc1 CHEMBL475495 IC50 8.8 nM
CCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3741496 IC50 9.0 nM
CCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3740060 IC50 9.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccc(F)cc3)cc2)C1 CHEMBL3739695 IC50 9.0 nM
COc1cc(CN2CC(C(=O)O)C2)ccc1OCc1ccc(Cl)cc1Cl CHEMBL3741364 IC50 9.0 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)cc2)c[nH]1 CHEMBL514170 IC50 9.6 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1 CHEMBL1093823 IC50 9.6 nM
Cc1cc(CC(C)C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL241050 EC50 9.9 nM
CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC CHEMBL117723 IC50 10.0 nM
CCc1cc(CN2CC(C(=O)O)C2)ccc1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL375488 IC50 10.0 nM
CCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3742304 IC50 10.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cccc(Cl)c3)cc2)C1 CHEMBL3742245 IC50 10.0 nM
CCCCCCCCc1ccc([C@H]2C[C@H](COP(=O)(O)O)N[C@@H]2CO)cc1 CHEMBL393055 EC50 10.2 nM
CCCCCC[C@@H]1CCc2cc([C@H]3CC[C@](N)(COP(=O)(O)O)C3)ccc2C1 CHEMBL3806205 EC50 10.7 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(-c5ccccc5)cc4)n3)cc2)C1 CHEMBL195025 IC50 11.0 nM
CCCCCCCCCc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL224623 IC50 11.0 nM
N#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)c1 CHEMBL2048287 EC50 11.0 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@@H](N)COP(=O)(O)O)n2)cc1 CHEMBL190865 EC50 12.0 nM
CC(C)Oc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL196357 IC50 12.0 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CC5)cc4)n3)cc2)C1 CHEMBL371985 IC50 12.0 nM
Cc1cc(CN2CC(C(=O)O)C2)cc(C)c1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL224853 IC50 12.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(/C=C/c3c(Cl)cccc3Cl)ccc12 CHEMBL4218826 pEC50 12.59 nM
O=C(O)CCN1CCC2(CC1)COc1cc(SCc3c(Cl)cccc3Cl)ccc12 CHEMBL4205124 pEC50 12.59 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCCCc3ccccc3)cc2)c[nH]1 CHEMBL515917 IC50 12.8 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(=O)N(C)C)no2)cc1C#N CHEMBL3921214 EC50 12.9 nM
CCCCCCCCCCCCCCNCCCP(=O)(O)O CHEMBL334213 IC50 13.0 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc([C@@H]5CCC(F)(F)C5)cc4)n3)cc2)N1 CHEMBL209076 IC50 13.0 nM
Cc1cc(CN2CC(C(=O)O)C2)ccc1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL224005 IC50 13.0 nM
CCCCCC(=O)c1ccc(CN2CCC(C(=O)O)C2)cc1 CHEMBL3741172 IC50 13.0 nM
CCCCCCCCCCCCCC1CCCC(CCP(C)(=O)O)N1 CHEMBL187692 IC50 15.0 nM
CC[C@H](C)Oc1ccc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)cc1C#N CHEMBL378054 EC50 15.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCCO)no2)cc1C#N CHEMBL3951270 EC50 15.06 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NCC(=O)N(C)C)no2)cc1C#N CHEMBL3922998 EC50 15.23 nM
CCc1cccc(Cl)c1COc1ccc2c(c1)OCC21CCN(CC(C)C(=O)O)CC1 CHEMBL4205225 pEC50 15.85 nM
O=C(O)CCCN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3Cl)ccc12 CHEMBL4204437 pEC50 15.85 nM
CCCc1cccc(Cl)c1COc1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1 CHEMBL4205878 pEC50 15.85 nM
CCc1cccc(Cl)c1COc1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1 CHEMBL4210234 pEC50 15.85 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(N)(CO)COP(O)(O)=S)n2)cc1 CHEMBL541890 EC50 16.0 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc([C@H]5CCC(F)(F)C5)cc4)n3)cc2)N1 CHEMBL210257 IC50 16.0 nM
O=C(O)C1CN(Cc2ccc(-c3noc(-c4cc(-c5ccccc5)c(C(F)(F)F)s4)n3)cc2)C1 CHEMBL225575 IC50 16.0 nM
CCCCCCOc1ccc(CN2CCC(C(=O)O)CC2)cc1 CHEMBL3739759 IC50 16.0 nM
O=C(O)C1CN(Cc2ccc(CCc3ccccc3)cc2)C1 CHEMBL3741743 IC50 16.0 nM
Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(Cl)c3)s1)CCN(CCC(=O)O)C2 CHEMBL3769933 pEC50 16.6 nM
CCCCCCCCCCCCCC[C@H]1CC[C@H](CCP(=O)(O)O)N1 CHEMBL187588 IC50 17.0 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(N)(CO)COP(=O)(O)O)n2)cc1 CHEMBL537849 EC50 17.0 nM
CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3)cc2)n1 CHEMBL1951304 EC50 17.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(Cl)c2)C1 CHEMBL224571 IC50 18.0 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)CC(F)OP(=O)(O)O)cc1 CHEMBL226612 EC50 19.0 nM
CCCCCCCOc1ccc(CC[C@](C)(N)CCP(=O)(O)O)cc1 CHEMBL1086170 EC50 19.0 nM
CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CC[C@@H]2CC(=O)O)cc1C(F)(F)F CHEMBL3359523 EC50 19.0 nM
Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(CO)CO)C2 CHEMBL1836215 pEC50 19.95 nM
O=P(O)(O)OCCN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3Cl)ccc12 CHEMBL4205748 pEC50 19.95 nM
CCc1cccc(CC)c1COc1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1 CHEMBL4203755 pEC50 19.95 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3OC(F)(F)F)ccc12 CHEMBL4217573 pEC50 19.95 nM
CC(C)(C)c1ccc(-c2noc(-c3ccc(CN4CC(C(=O)O)C4)cc3)n2)cc1 CHEMBL364899 IC50 20.0 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc(C5CCCCC5)cc4)n3)cc2)N1 CHEMBL210520 IC50 20.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N)no2)cc1C#N CHEMBL3902160 EC50 20.11 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(C5CCC(F)(F)CC5)cc4)n3)cc2)C1 CHEMBL208648 IC50 21.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(C(F)(F)F)c2)C1 CHEMBL224549 IC50 21.0 nM
Cc1ccc(CCCC(=O)c2ccc(CC[C@@](C)(N)COP(=O)(O)O)n2C)cc1 CHEMBL1951588 EC50 21.0 nM
N#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)c1 CHEMBL2048293 EC50 21.0 nM
CCCCCCCCc1ccc([C@@H]2C[C@@H](CO)N[C@H]2COP(=O)(O)O)cc1 CHEMBL247901 EC50 21.3 nM
CC/N=C1\S/C(=C\c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1CC CHEMBL1910690 EC50 22.0 nM
O=C(O)C1CN(Cc2cc3cc(-c4ccc5ccccc5c4)ccc3s2)C1 CHEMBL3883597 EC50 22.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL425563 IC50 23.0 nM
O=C(O)C1CN(Cc2ccc(-c3ccc(Cl)c(Cl)c3)cc2)C1 CHEMBL3742345 IC50 23.0 nM
CCCCCCCCCCCCCCN(C)CCCP(=O)(O)O CHEMBL185100 IC50 24.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2cnc(OC(C)C(F)(F)F)c(Cl)c2)n1 CHEMBL209484 EC50 24.0 nM
O=C(O)C[C@H]1CCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 CHEMBL3358920 EC50 24.4 nM
O=C(O)CCNCc1cc2cc(-c3ccc4ccccc4c3)ccc2s1 CHEMBL3883972 EC50 25.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(C#Cc3ccccc3Cl)ccc12 CHEMBL4213894 pEC50 25.12 nM
CC(C)c1cccc(Cl)c1COc1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1 CHEMBL4205333 pEC50 25.12 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(C)(N)COP(=O)(O)O)n2)cc1 CHEMBL188881 EC50 26.0 nM
CCCCCCOc1ccc(CN2CC[C@@H](C(=O)O)C2)cc1 CHEMBL3739509 IC50 26.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCC2CCCCC2)cc1 CHEMBL473562 IC50 26.2 nM
CCCCCCOc1ccc(CN2CCC(C(=O)O)C(C)C2)cc1 CHEMBL3739964 IC50 28.0 nM
Cc1nc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL241052 EC50 28.6 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@@H](N)COP(O)(O)=S)n2)cc1 CHEMBL188826 EC50 29.0 nM
CCCCCCCCCc1ccc(CN2CCC(C(=O)O)C2)cc1 CHEMBL224703 IC50 29.0 nM
O=C(O)C1CN(Cc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)c(F)c2)C1 CHEMBL1651861 EC50 29.0 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4CC[C@@H](CCC(=O)O)N4)cc3)no2)cc1 CHEMBL377637 IC50 30.0 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc(C5CCCC5)c(F)c4)n3)cc2)N1 CHEMBL426688 IC50 30.0 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)CCP(=O)(O)O)cc1 CHEMBL228139 EC50 30.0 nM
CCCCCCc1ccc(OC[C@@H](N)CCP(=O)(O)O)cc1 CHEMBL228103 EC50 31.0 nM
O=C(O)CCNCc1cc2c(-c3ccc4ccccc4c3)cccc2s1 CHEMBL3883812 EC50 31.0 nM
CCc1cccc(Cl)c1COc1ccc2c(c1)OCC21CCCN(CCC(=O)O)C1 CHEMBL4206573 pEC50 31.62 nM
O=C(O)CN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3Cl)ccc12 CHEMBL4209307 pEC50 31.62 nM
O=C(Cc1ccccc1)c1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3740604 IC50 32.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCO)no2)cc1C#N CHEMBL3894716 EC50 32.28 nM
O=C(O)C1CN(Cc2cc(Cl)c(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(Cl)c2)C1 CHEMBL426191 IC50 33.0 nM
CCCCCCCCc1cccc(NC(=O)[C@H](N)CCP(=O)(O)O)c1 CHEMBL389033 EC50 33.0 nM
CCCCCCCCCCCCCCN1CCC(O)(P(=O)(O)O)C1 CHEMBL184237 IC50 34.0 nM
CCOC(=O)/C(=C\c1ccc(OC(F)F)cc1)C1=Nn2c(nnc2-c2ccc(Cl)cc2)SC1 CHEMBL1412583 IC50 34.0 nM
C/N=C1\S/C(=C\c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1C CHEMBL1910689 EC50 34.0 nM
Cc1ccccc1COc1ccc(CN2CC(C(=O)O)C2)cc1 CHEMBL3740768 IC50 35.0 nM
CC(C)(C)[C@H]1CC[C@H](Oc2cc(Cl)c3ccccc3c2CN2CCC(C(=O)O)CC2)CC1 CHEMBL4740175 EC50 36.0 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@H](N)COP(=O)(O)O)n2)cc1 CHEMBL187712 EC50 37.0 nM
C/N=C1\S/C(=C\c2cc(C)n(Cc3ccc(F)cc3F)c2C)C(=O)N1C CHEMBL1910691 EC50 37.0 nM
Cc1cc([C@H]2C[C@H]2C(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL247766 EC50 37.7 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NC(=O)N3CC(O)C3)no2)cc1C#N CHEMBL3893172 EC50 39.8 nM
O=C(O)CCN1CCC2(CC1)COc1cc(C#Cc3ccccc3)ccc12 CHEMBL4208055 pEC50 39.81 nM
CCCCCCCCCCCCCCN1CCC(C(O)P(=O)(O)O)C1 CHEMBL363008 IC50 40.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1 CHEMBL208924 EC50 40.0 nM
CCCCCCCCCCc1ccc(NC(=O)[C@H](N)COP(=O)(O)O)cc1 CHEMBL334038 EC50 41.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(F)c2)C1 CHEMBL389880 IC50 41.0 nM
CCCCCCCCc1cccc(NC[C@H](N)CCP(=O)(O)O)c1 CHEMBL228138 EC50 41.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccccc3)c(F)c2)C1 CHEMBL3741775 IC50 41.0 nM
CCCCCCc1ccc(NC(=O)[C@H](N)COP(=O)(O)O)cc1 CHEMBL115344 EC50 43.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(Br)c2)n1 CHEMBL210316 EC50 43.0 nM
Cc1cc(CCC(=O)O)ccc1-c1nnn(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL210345 EC50 43.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCc2ccccc2)cc1 CHEMBL514302 IC50 43.6 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL475405 IC50 43.6 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OCC(F)(F)F)c(C#N)c2)n1 CHEMBL379380 EC50 44.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N)no2)cc1C#N CHEMBL3899384 EC50 44.55 nM
CCCCCCc1ccc(OC[C@H](N)CCP(=O)(O)O)cc1 CHEMBL228049 EC50 47.0 nM
CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CC[C@@H]2CC(=O)O)cc1C#N CHEMBL3359522 EC50 47.0 nM
CCOc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 CHEMBL371743 IC50 48.0 nM
O=C(O)CCCNCc1cc2cccc(-c3cccc(-c4ccccc4)c3)c2s1 CHEMBL3884809 EC50 49.0 nM
COCCS(=O)(=O)N[C@@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3933952 EC50 49.98 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(CCC(F)(F)F)cc4)n3)cc2)C1 CHEMBL425602 IC50 50.0 nM
N[C@@H](COP(=O)(O)O)[C@H](O)/C=C/CCCCCCCCCCNc1ccc([N+](=O)[O-])c2nonc12 CHEMBL199754 Log EC50 50.12 nM
CCCCCCCCc1ccc(-c2c[nH]c(C(C)(N)COP(O)(O)=S)n2)cc1 CHEMBL364950 EC50 51.0 nM
C/N=C1\S/C(=C\c2cc(C)n(Cc3ccccc3F)c2C)C(=O)N1C CHEMBL1910688 EC50 51.0 nM
O=C(O)CNCc1cc2c(-c3ccc4ccccc4c3)cccc2s1 CHEMBL3883447 EC50 51.0 nM
CCCCCCCCc1ccc(NC(=O)[C@H](N)COP(=O)(O)O)cc1 CHEMBL422074 EC50 52.0 nM
CCCCCCCCc1cccc(NC(=O)[C@H](N)COP(=O)(O)O)c1 CHEMBL228102 EC50 52.0 nM
O=C(O)C1CN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)c(Br)c2)C1 CHEMBL224599 IC50 53.0 nM
Cc1cc(C)c(Nc2cccc3c(C)n[nH]c(=O)c23)c(C)c1 CHEMBL4749473 Activity 53.0 nM
CCCCCCc1ccc(NC(=O)[C@@H](N)COP(=O)(O)O)cc1 CHEMBL114031 EC50 55.0 nM
CCOc1ccc(-c2nc(-c3cccc4c3CCC4O)no2)cc1OCC CHEMBL3919445 EC50 56.81 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(C5CCCCC5)cc4)n3)cc2)C1 CHEMBL377828 IC50 57.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(=O)(=O)CCO)no2)cc1C#N CHEMBL3895230 EC50 57.11 nM
CCC/N=C1\S/C(=C\c2ccc(OC[C@@H](O)CO)c(Cl)c2)C(=O)N1c1ccccc1C CHEMBL1095833 EC50 59.1 nM
O=C(O)C[C@@H]1CC[C@H](c2ccc(-c3noc(-c4ccc(C5CCCC5)cc4F)n3)cc2)N1 CHEMBL210782 IC50 60.0 nM
O=C(O)CCCNCc1cc2c(-c3ccc4ccccc4c3)cccc2s1 CHEMBL3885331 EC50 60.0 nM
CCCCN(C(=O)c1ccccc1F)c1nnc(-c2ccc(CN3CC(C(=O)O)C3)cc2)s1 CHEMBL2207778 EC50 62.0 nM
CC(CN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3Cl)ccc12)C(=O)O CHEMBL4217349 pEC50 63.1 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3c(F)cccc3Cl)ccc12 CHEMBL4207361 pEC50 63.1 nM
CCC(C)(C)[C@H]1CC[C@H](Oc2cc(C)c3ccccc3c2CN2CCC(C(=O)O)CC2)CC1 CHEMBL4779029 EC50 67.0 nM
O=C(O)C[C@@H]1CN[C@@H](c2ccc(-c3noc(-c4ccc(C5CCCC5)cc4)n3)cc2)C1 CHEMBL211006 IC50 68.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL473238 IC50 70.4 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1 CHEMBL206940 EC50 73.0 nM
CCCCCCOc1ccc(CN2CCC(C(=O)O)C2)cc1 CHEMBL3741459 IC50 75.0 nM
CCCCCCCCc1ccc(NC(=O)[C@H](N)CCP(=O)(O)O)cc1 CHEMBL227851 EC50 76.0 nM
CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NC(=O)N3CC(O)C3)no2)cc1C#N CHEMBL3910269 EC50 76.11 nM
CCCCCCCCc1ccc2[nH]c([C@@H](N)[C@@H](C)OP(=O)(O)O)nc2c1 CHEMBL183894 EC50 77.0 nM
COc1cc(CN2CC(C(=O)O)C2)ccc1OCc1cc(-c2ccccc2)c(C(F)(F)F)s1 CHEMBL224800 IC50 77.0 nM
O=C(O)C1CN(Cc2ccc(OCc3ccccc3)cc2)C1 CHEMBL3739977 IC50 77.0 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H]4CC[C@@H](CCC(=O)O)N4)cc3)no2)cc1 CHEMBL210468 IC50 80.0 nM
O=C(O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12 CHEMBL3358955 EC50 81.0 nM
Cc1nn(C(=O)/C=C/c2cccc(S(N)(=O)=O)c2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL590135 EC50 82.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(C(F)(F)F)c1 CHEMBL1093429 IC50 87.2 nM
O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)n3)ccc21 CHEMBL1916559 EC50 88.0 nM
Cc1cc(S(N)(=O)=O)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1088177 EC50 96.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL475253 IC50 99.8 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H]4CC[C@@H](CC(=O)O)N4)cc3)no2)cc1 CHEMBL210785 IC50 100.0 nM
O=C(O)CCN1CCCC2(COc3cc(OCc4c(Cl)cccc4Cl)ccc32)C1 CHEMBL4218296 pEC50 100.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1 CHEMBL473563 IC50 104.0 nM
C[C@@H](Oc1ccc(CN2CC(C(=O)O)C2)cc1)c1ccccc1 CHEMBL3740494 IC50 108.0 nM
N#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)c1 CHEMBL1916399 EC50 109.0 nM
CCCCCCCCc1ccc(NC(=O)[C@@H](N)COP(=O)(O)O)cc1 CHEMBL332050 EC50 110.0 nM
CCCCCCCCCCCCCCNC1CCCC(P(=O)(O)O)C1 CHEMBL186921 IC50 110.0 nM
CC(C)Oc1ccc(COc2ccc3c(c2)CCCN(S(=O)(=O)CCC(=O)O)C3)cc1C#N CHEMBL5405061 EC50 110.0 nM
Cc1cc(S(=O)(=O)NCCC(=O)O)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1082869 EC50 114.0 nM
COc1cc(CN2CC(C(=O)O)C2)ccc1OCc1ccccc1Cl CHEMBL3741222 IC50 115.0 nM
Cc1cc(CCC(=O)O)ccc1-c1ncc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL211046 EC50 120.0 nM
O=C(O)C1CCN(Cc2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL224799 IC50 120.0 nM
CCCCCCOc1ccc(CN2CCC[C@@H](C(=O)O)C2)cc1 CHEMBL3740739 IC50 125.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3C(F)(F)F)ccc12 CHEMBL4208787 pEC50 125.89 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3ccccc3Cl)ccc12 CHEMBL4204779 pEC50 125.89 nM
O=C(O)C1CNC(c2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL377968 IC50 130.0 nM
Cc1nn(C(=O)/C=C/c2ccncc2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL590383 EC50 130.0 nM
CCCCCCCCc1ccc([C@H]2C[C@H](CO)N[C@@H]2COP(=O)(O)O)cc1 CHEMBL247698 EC50 133.8 nM
CCOc1ccc(-c2nc(-c3cccc4c3CCC4NCCO)no2)cc1OCC CHEMBL3922179 EC50 135.94 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4C[C@@H](CC(=O)O)CN4)cc3)no2)cc1 CHEMBL378061 IC50 140.0 nM
CCCN(CC1CC1)c1cc(C(=O)Nc2ccc3[nH]ncc3c2)ncn1 CHEMBL1080865 EC50 142.0 nM
O=C(O)CCCNCc1cc2cc(-c3ccc4ccccc4c3)ccc2s1 CHEMBL3883377 EC50 143.0 nM
C/N=C1\S/C(=C\c2cc(C)n(Cc3ccccc3)c2C)C(=O)N1C CHEMBL1910687 EC50 144.0 nM
O=C(O)C1CN(Cc2ccc(-c3cc(Cl)cc(Cl)c3)cc2)C1 CHEMBL3741338 IC50 148.0 nM
Cc1cc(CCC(=O)O)ccc1-n1nnc(-c2ccc(OC(C)C)c(C#N)c2)n1 CHEMBL380040 EC50 150.0 nM
O=C(O)CCCCNCc1cc2c(-c3ccc4ccccc4c3)cccc2s1 CHEMBL3883572 EC50 152.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3Cl)ccc12 CHEMBL4215002 pEC50 158.49 nM
CCCCCCCCCCCCc1ccc(NC(=O)[C@H](N)COP(=O)(O)O)cc1 CHEMBL116953 EC50 160.0 nM
Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(CCC(=O)O)C2 CHEMBL1836169 pEC50 162.18 nM
CC(C)(C)[C@H]1CC[C@H](Oc2cc(I)c3ccccc3c2CN2CCC(C(=O)O)CC2)CC1 CHEMBL4758438 EC50 165.0 nM
O=C(O)CCNCCCc1ccc(OCCCCCc2ccccc2)cc1 CHEMBL1683041 EC50 170.0 nM
COCCS(=O)(=O)N[C@H]1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 CHEMBL3931243 EC50 173.55 nM
O=C(O)C1CN(Cc2cc3c(-c4ccc5ccccc5c4)cccc3s2)C1 CHEMBL3884966 EC50 175.0 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@@H]4CC[C@@H](C(=O)O)N4)cc3)no2)cc1 CHEMBL427221 IC50 180.0 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)c(C(F)(F)F)c2)c[nH]1 CHEMBL1090829 IC50 184.0 nM
Cc1cc(O)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1 CHEMBL1081645 EC50 191.0 nM
COCC/N=C1\S/C(=C\c2cc(C)n(Cc3ccccc3)c2C)C(=O)N1C CHEMBL1910802 EC50 196.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3cccc(Cl)c3Cl)ccc12 CHEMBL4210576 pEC50 199.53 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3cc(Cl)ccc3Cl)ccc12 CHEMBL4205714 pEC50 199.53 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4CC[C@@H](CC(=O)O)N4)cc3)no2)cc1 CHEMBL210352 IC50 200.0 nM
Cc1cc(CCC(=O)O)ccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL379612 EC50 200.0 nM
CCCCCCCOc1ccc(CC[C@](C)(N)CC(=O)O)cc1 CHEMBL1086172 EC50 200.0 nM
C[C@](N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)cc2)c[nH]1 CHEMBL474418 IC50 207.0 nM
Cc1cc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)ccc1OC(C)C CHEMBL208898 EC50 210.0 nM
Cc1nc(CC(C)C)cc(-c2nc(-c3cc(F)c(O[C@@H]4CCC(=O)N(C)C4)cc3Cl)no2)n1 CHEMBL3752660 EC50 215.0 nM
Cc1cc(CCC(=O)O)ccc1-c1ccc(-c2ccc(OC(C)C)c(C#N)c2)s1 CHEMBL377181 EC50 220.0 nM
CCCCCCCCCCCCCC1CCCCN1CCCP(=O)(O)O CHEMBL187061 IC50 230.0 nM
CC(CNCc1cc2cc(-c3ccc4ccccc4c3)ccc2s1)C(=O)O CHEMBL3884995 EC50 232.0 nM
Cc1cc(OC2CCCCC2)c(CN2CCC(C(=O)O)CC2)c2ccccc12 CHEMBL4778961 EC50 236.0 nM
CC/N=C1\S/C(=C\c2cc(C)n(-c3ccccc3)c2C)C(=O)N1CC CHEMBL1910681 EC50 237.0 nM
CC(Oc1ccc(CN2CC(C(=O)O)C2)cc1)c1ccccc1 CHEMBL3740188 IC50 255.0 nM
Cc1cc(O)ccc1NC(=O)c1cc(NC2CCCCC2)ncn1 CHEMBL1081654 EC50 258.0 nM
CCOc1ccc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)cc1C(F)(F)F CHEMBL211689 EC50 260.0 nM
Cc1ccccc1-c1noc(-c2ccc(C3CCCCC3)cc2)n1 CHEMBL208786 EC50 266.0 nM
Cc1cc(O[C@H]2CC[C@H](C(C)(C)C)CC2)c(CNCC(=O)O)c2ccccc12 CHEMBL4798888 EC50 267.0 nM
CCCCCCCCCCCCCCN1CCC(O)(P(C)(=O)O)CC1 CHEMBL187645 IC50 270.0 nM
COc1cc(-c2nc(-c3ccc(CCC(=O)O)cc3C)no2)ccc1OC(C)C CHEMBL212580 EC50 270.0 nM
O=C(O)CNCc1cc2cccc(-c3ccc4ccccc4c3)c2s1 CHEMBL3885275 EC50 272.0 nM
CCc1cc(-c2noc(-c3sc(C)c4c3C[C@@H]3[C@H]4C3(C)C)n2)cc(C)c1CCC(=O)O CHEMBL3105479 EC50 275.0 nM
O=C(Cc1ccccc1)c1ccc(CN2CCC(C(=O)O)C2)cc1 CHEMBL3739593 IC50 277.0 nM
CCCCCCCOc1ccc(CC[C@](C)(N)C(=O)O)cc1 CHEMBL1086171 EC50 280.0 nM
O=C(O)CCNCc1cc2cccc(-c3ccc4ccccc4c3)c2s1 CHEMBL3883456 EC50 280.0 nM
CC(C)Cc1ccc(-c2nc(-c3ccc([C@H]4C[C@H](CC(=O)O)CN4)cc3)no2)cc1 CHEMBL378300 IC50 300.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3cc(Cl)nc(Cl)c3)ccc12 CHEMBL4218094 pEC50 316.23 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3cccc(Cl)c3)ccc12 CHEMBL4210080 pEC50 316.23 nM
Cc1nn(C(=O)/C=C/c2cccc(C(F)(F)F)c2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL590134 EC50 325.0 nM
NC(CNCc1cc2c(-c3ccc4ccccc4c3)cccc2s1)C(=O)O CHEMBL3883471 EC50 329.0 nM
C/N=C1\S/C(=C/c2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1OC CHEMBL1734070 EC50 339.0 nM
Cc1cc(-c2nc(-c3cc(C)c(OC[C@@H]4CCC(=O)N4)c(C)n3)no2)cc(CC(C)C)n1 CHEMBL3753300 EC50 340.0 nM
Cc1nn(C(=O)/C=C/c2cccnc2)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL590384 EC50 345.0 nM
Cc1cc(-c2nc(-c3ccc(O[C@H]4CCC(=O)NC4)c(C)n3)no2)cc(NC(C)C)n1 CHEMBL3753609 EC50 350.0 nM
O=C(O)CNCc1cc2cc(-c3ccc4ccccc4c3)ccc2s1 CHEMBL3885468 EC50 350.0 nM
O=C(O)c1ccc(CNCc2cc3c(-c4ccc5ccccc5c4)cccc3s2)cc1 CHEMBL3884011 EC50 356.0 nM
Cc1nc(CC(C)C)cc(-c2nc(-c3ccc(O[C@@H]4CCC(=O)NC4)c(F)c3)no2)n1 CHEMBL3753479 EC50 360.0 nM
CCCCCCCCc1ccc2[nH]c(C(C)(N)COP(=O)(O)O)nc2c1 CHEMBL433593 EC50 370.0 nM
O=C(O)CCCNCc1cc2cccc(-c3ccc4ccccc4c3)c2s1 CHEMBL3884038 EC50 370.0 nM
CCCCCCCCc1ccc2[nH]c([C@H](N)CO)nc2c1 CHEMBL186815 EC50 390.0 nM
O=C(O)CC1CNC(c2ccc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1 CHEMBL377855 IC50 390.0 nM
CCCCCCCCOc1cc(C)c2ccccc2c1CNCCC(=O)O CHEMBL4742052 EC50 406.0 nM
O=C(O)C1CN(Cc2ccc(-c3cccc(C(F)(F)F)c3)cc2)C1 CHEMBL3742100 IC50 409.0 nM
CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)cc1C#N CHEMBL3359520 EC50 410.0 nM
O=C(O)CCCCNCc1cc2cccc(-c3ccc4ccccc4c3)c2s1 CHEMBL3883555 EC50 412.0 nM
C[C@](N)(COP(=O)(O)O)C(=O)Nc1ccc(Oc2ccc(-c3ccccc3)cc2)cc1 CHEMBL515603 IC50 455.0 nM
Cc1cc(CCC(=O)O)ccc1-c1nnc(-c2ccc(OC(C)C)c(C#N)c2)o1 CHEMBL211081 EC50 460.0 nM
CCCCCCCCc1ccc(NC(=O)[C@H](N)COP(=O)(O)O)cc1 CHEMBL227371 EC50 480.0 nM
Cc1nn(C(=O)/C=C/c2cccc3[nH]ccc23)c2c1[C@H]1[C@@H](C2)C1(C)C CHEMBL601062 EC50 505.0 nM
O=C(O)C1CN(Cc2cc3cccc(-c4ccc5ccccc5c4)c3s2)C1 CHEMBL3883579 EC50 506.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(F)c2)n1 CHEMBL380253 EC50 530.0 nM
O=C(O)CCCNCc1cc2cccc(-c3ccc(C(F)(F)F)cc3)c2s1 CHEMBL3884795 EC50 552.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(C3CCCCC3)cc2)n1 CHEMBL208168 EC50 591.0 nM
CC(C)(C)[C@H]1CC[C@H](Oc2ccc3ccccc3c2CN2CCC(C(=O)O)CC2)CC1 CHEMBL4762836 EC50 602.0 nM
CCCCCCCCCCCCNC(=O)[C@@H](N)COP(=O)(O)O CHEMBL324358 EC50 645.5 nM
C/N=C1\S/C(=C\c2cc(C)n(-c3ccc(F)cc3)c2C)C(=O)N1C CHEMBL1910674 EC50 652.0 nM
CCCCCCCCCCCCCCN1CCCC1CCP(=O)(O)O CHEMBL185447 IC50 660.0 nM
CCCCCCCCCCCCCCC1CCCN1CCCP(=O)(O)O CHEMBL185066 IC50 680.0 nM
O=C(O)CCCCNCc1cc2cc(-c3ccc4ccccc4c3)ccc2s1 CHEMBL3883621 EC50 709.0 nM
C/N=C1\S/C(=C\c2cc(C)n(-c3ccccc3F)c2C)C(=O)N1C CHEMBL1910655 EC50 721.0 nM
NC(CNCc1cc2cc(-c3ccc4ccccc4c3)ccc2s1)C(=O)O CHEMBL3884173 EC50 728.0 nM
CCc1cc(-c2noc(-c3cc(C)c(CN(C)CC(C)C)s3)n2)cc(C)c1OC[C@@H](O)CNC(=O)CO CHEMBL3798837 EC50 753.0 nM
O=C(O)Cc1cccc(NCc2cc3cc(-c4ccc5ccccc5c4)ccc3s2)c1 CHEMBL3884077 EC50 769.0 nM
O=C(O)C1CN(Cc2ccc(Oc3ccc(Cl)cc3)cc2)C1 CHEMBL3740219 IC50 789.0 nM
O=C(O)CN1CCC2(CC1)COc1cc(S(=O)(=O)Cc3c(Cl)cccc3Cl)ccc12 CHEMBL4209494 pEC50 794.33 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(C(F)(F)C(C)C)cn2)n1 CHEMBL209567 EC50 820.0 nM
Cc1cc(CCCC(=O)O)ccc1-c1noc(-c2ccc(C3CCCCC3)cc2)n1 CHEMBL208224 EC50 840.0 nM
CCCCCCCCc1ccc(-c2c[nH]c([C@H](N)CO)n2)cc1 CHEMBL190529 EC50 860.0 nM
CC(CNCc1cc2cccc(-c3ccc4ccccc4c3)c2s1)C(=O)O CHEMBL3884134 EC50 887.0 nM
COc1ccc(/C=C/C(=O)n2nc(C)c3c2C[C@@H]2[C@H]3C2(C)C)cc1OC CHEMBL600762 EC50 900.0 nM
Cc1cc(CCC(=O)O)ccc1-c1noc(-c2cnc(OC(C)C)c(Cl)c2)n1 CHEMBL210695 EC50 950.0 nM
Cc1cc(S(=O)(=O)Nc2cccc(-c3cc(C)c(C(=O)N(C)[C@@H](CCN(C)C)C(=O)O)c(C)c3)c2)c(C)cc1Cl CHEMBL2178814 IC50 978.0 nM
CC(C)(C)c1ccc(-c2nnc(-c3ccc(CN4CC(C(=O)O)C4)cc3)o2)cc1 CHEMBL196149 IC50 1000.0 nM
CCCCCCCOc1ccc(CC[C@](C)(N)CCN2CC(=O)NS2(=O)=O)cc1 CHEMBL1083841 EC50 1000.0 nM
O=C(O)CCN1CCC2(CC1)COc1cc(OCc3ccccc3)ccc12 CHEMBL4213649 pEC50 1000.0 nM