FC(F)(F)c1cccc2c1CCC1(CCN(c3ccc(-c4nnc(Cc5cccnc5)o4)nn3)CC1)O2 CHEMBL593108 IC50 0.03 nM
CCNc1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL564507 IC50 0.04 nM
COc1ccc(-c2nc3ccc(NCc4ccc(Cl)c(C(F)(F)F)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494748 IC50 0.05 nM
Clc1cccc2c1CCC1(CCN(c3ccc(-c4nnc(Cc5cccnc5)o4)nn3)CC1)O2 CHEMBL1276595 IC50 0.06 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CCc4ccccc4O3)CC2)nn1 CHEMBL594289 IC50 0.068 nM
Fc1ccc(F)c2c1CCC1(CCN(c3ccc(-c4nnc(Cc5cccnc5)o4)nn3)CC1)O2 CHEMBL1276623 IC50 0.1 nM
COc1ccc(C(=O)Nc2ncc(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL552173 IC50 0.2 nM
Cc1cccc2c1CCC1(CCN(c3ccc(-c4nnc(Cc5cccnc5)o4)nn3)CC1)O2 CHEMBL1276653 IC50 0.2 nM
Fc1cccc2c1CCC1(CCN(c3ccc(-c4nnc(Cc5cccnc5)o4)nn3)CC1)O2 CHEMBL1276654 IC50 0.3 nM
O=C(NCC(O)c1cccnc1)c1ccc(N2CCC3(CCc4c(cccc4C(F)(F)F)O3)CC2)nn1 CHEMBL605412 IC50 0.45 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)CC(O)c2ccccc2O3)nn1 CHEMBL595247 IC50 0.48 nM
O=C(CO)NCCN1C(=O)COc2ccc(NCc3ccc(Cl)c(Cl)c3)cc21 CHEMBL572876 IC50 0.5 nM
OCc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127535 IC50 0.5 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)Oc2ccccc2CC3O)nn1 CHEMBL594084 IC50 0.56 nM
COCCOc1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL549625 IC50 0.6 nM
COc1ccc(C(=O)Nc2ncc(Cc3ccc(F)c(C(F)(F)F)c3)s2)cc1OCCO CHEMBL557445 IC50 0.6 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)CC(=O)c2ccccc2O3)nn1 CHEMBL607314 IC50 0.69 nM
COc1ccc(C(=O)Nc2ncc(Cc3cc(Cl)cc(Cl)c3)s2)cc1OCCO CHEMBL552126 IC50 1.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3ccc(Cl)c(Cl)c3)s2)cc1OCCO CHEMBL550800 IC50 1.0 nM
O=C(NCC(O)c1cccnc1)c1ccc(N2CCC3(CCc4c(Cl)cccc4O3)CC2)nn1 CHEMBL595254 IC50 1.0 nM
Cc1cccc2c1CCC1(CCN(c3ccc(C(=O)NCC(O)c4cccnc4)nn3)CC1)O2 CHEMBL595255 IC50 1.0 nM
FC(F)(F)c1cccc2c1CCC1(CCN(c3ccc(-c4nc(Cc5cccnc5)n[nH]4)nn3)CC1)O2 CHEMBL594071 IC50 1.0 nM
OCc1nc(-c2cnc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)s2)no1 CHEMBL1087015 IC50 1.0 nM
c1cncc(Cc2nnc(-c3ccc(N4CCC5(CCc6ccccc6O5)CC4)nn3)o2)c1 CHEMBL1276685 IC50 1.0 nM
O=C(O)Cn1nnc(-c2cc(N3CCC(Oc4cc(F)ccc4Br)CC3)no2)n1 CHEMBL1938870 IC50 1.0 nM
O=C(Nc1nc2c(s1)CC(O)CC2)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093861 INH 1.0 nM
O=C(O)Cn1nnc(-c2cc(N3CCC4(CCc5c(OC(F)(F)F)cccc5O4)CC3)no2)n1 CHEMBL3970644 IC50 1.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CCc5c(OC(F)(F)F)cccc5O4)CC3)s2)n1 CHEMBL3895997 IC50 1.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5c(OC(F)(F)F)cccc5O4)CC3)s2)n1 CHEMBL3914019 IC50 1.0 nM
O=C(O)Cn1nnc(-c2cc(N3CCC4(CCc5c(Br)cccc5O4)CC3)no2)n1 CHEMBL3942017 IC50 1.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5c(Br)cccc5O4)CC3)s2)n1 CHEMBL3919514 IC50 1.0 nM
Cc1cccc2c1CCC1(CCN(c3ncc(-c4nnn(CC(=O)O)n4)s3)CC1)O2 CHEMBL3979824 IC50 1.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CCc5c(cccc5C(F)(F)F)O4)CC3)s2)n1 CHEMBL3976984 IC50 1.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5c(cccc5C(F)(F)F)O4)CC3)s2)n1 CHEMBL3914136 IC50 1.0 nM
OCc1nsc(-c2ccc(N3CCC(c4ccc(C(F)(F)F)cc4)(C(F)(F)F)CC3)nn2)n1 CHEMBL4066506 IC50 1.2 nM
CCOc1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL549758 IC50 2.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3ccc(F)c(Cl)c3)s2)cc1OCCO CHEMBL552270 IC50 2.0 nM
O=C(NCC(O)c1cccnc1)c1ccc(N2CCC3(CCc4c(F)ccc(F)c4O3)CC2)nn1 CHEMBL594995 IC50 2.0 nM
Cc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127534 IC50 2.0 nM
Cc1csc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)n1 CHEMBL3127654 IC50 2.0 nM
OCc1noc(-c2ccc(N3CCC(c4ccc(C(F)(F)F)cc4)(C(F)(F)F)CC3)nn2)n1 CHEMBL4104190 IC50 2.3 nM
OCc1nnc(-c2ccc(N3CCC(c4ccc(C(F)(F)F)cc4)(C(F)(F)F)CC3)nn2)s1 CHEMBL4094042 IC50 2.5 nM
O=C(CO)NCCn1c(=O)c(C(F)(F)F)nc2ccc(NCc3cccc(C(F)(F)F)c3)cc21 CHEMBL575817 IC50 2.7 nM
COc1ccc(-c2nc3ccc(NCc4cccc(C(F)(F)F)c4)nc3n(CCC(N)=O)c2=O)cc1 CHEMBL521993 IC50 2.8 nM
O=C(Nc1ncc(CO)s1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4282070 IC50 2.8 nM
COc1ccc(C(=O)Nc2ncc(Cc3cc(F)cc(F)c3)s2)cc1OCCO CHEMBL552269 IC50 2.9 nM
COc1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL550172 IC50 3.0 nM
COc1ccc(/C=C/C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1 CHEMBL560271 IC50 3.0 nM
O=C(Nc1ccc(Cl)cc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315102 IC50 3.0 nM
OCc1cn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127543 IC50 3.0 nM
O=C(O)Cn1ccn(-c2cnc(N3CCC4(CCc5c(Cl)cccc5O4)CC3)s2)c1=O CHEMBL3939859 IC50 3.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CCc5c(Cl)cccc5O4)CC3)s2)n1 CHEMBL3892040 IC50 3.0 nM
CCCCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)cc1 CHEMBL4295170 IC50 3.0 nM
CCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CCO)cs2)cc1 CHEMBL4277121 IC50 3.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(F)c(C)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494359 IC50 3.1 nM
CCc1ccc(-c2nc3ccc(NCc4cccc(C(F)(F)F)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494544 IC50 3.2 nM
CCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CO)cs2)cc1 CHEMBL4278602 IC50 3.2 nM
COc1ccc(-c2nc3ccc(NCc4cccc(C(F)(F)F)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL493961 IC50 3.3 nM
O=C(Nc1ncc(CCO)s1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4289946 IC50 3.8 nM
O=C(Nc1nc(CO)cs1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4277371 IC50 3.8 nM
O=C(Nc1nc(CCO)cs1)c1ccc(CNc2ccccc2C(F)(F)F)s1 CHEMBL4293631 IC50 3.9 nM
CCN(CC)c1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL564740 IC50 4.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3cccc(Cl)c3)s2)cc1OCCO CHEMBL561588 IC50 4.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3cccc(OC(F)(F)F)c3)s2)cc1OCCO CHEMBL562268 IC50 4.0 nM
c1ccc(Cc2nnc(-c3ccc(N4CCC5(CCc6ccccc6O5)CC4)nn3)o2)nc1 CHEMBL1276686 IC50 4.0 nM
COc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127537 IC50 4.0 nM
Cc1ccc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3684085 IC50 4.0 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)cc2)n1 CHEMBL4282359 IC50 4.1 nM
O=C(Nc1nc(CCO)cs1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4288013 IC50 4.2 nM
O=C(Nc1nc(CO)cs1)c1ccc(CNc2ccccc2Cl)cc1 CHEMBL4283141 IC50 4.3 nM
CCCCCCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)cc1 CHEMBL4287233 IC50 4.5 nM
CCCCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CCO)cs2)s1 CHEMBL4285765 IC50 4.5 nM
OCc1nnc(-c2ccc(N3CCC(c4ccc(C(F)(F)F)cc4)(C(F)(F)F)CC3)nn2)o1 CHEMBL4086275 IC50 4.7 nM
CC(C)CCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)cc1 CHEMBL4286817 IC50 4.8 nM
CCCCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)s1 CHEMBL4284015 IC50 4.8 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccc(F)cc3)nn2)CC1 CHEMBL591781 IC50 5.0 nM
O=C(O)Cc1csc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)cc2)n1 CHEMBL4281222 IC50 5.1 nM
O=C(Nc1nc(CO)cs1)c1ccc(CNc2ccccc2C(F)(F)F)s1 CHEMBL4294042 IC50 5.1 nM
O=C(Nc1nc(CCCO)cs1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4280771 IC50 5.2 nM
CC(C)CCc1ccccc1NCc1ccc(C(=O)Nc2nc(CCO)cs2)cc1 CHEMBL4285064 IC50 5.3 nM
CCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)cc1 CHEMBL4290642 IC50 5.5 nM
O=C(O)Cc1csc(NC(=O)c2ccc(CNc3ccccc3Cc3ccccc3)cc2)n1 CHEMBL4283470 IC50 5.5 nM
COc1ccc(-c2nc3cnc(NCc4cccc(C(F)(F)F)c4)nc3n(CCC(N)=O)c2=O)cc1 CHEMBL522872 IC50 5.6 nM
O=C(NCC(O)c1cccnc1)c1ccc(N2CCC3(CCc4c(F)cccc4O3)CC2)nn1 CHEMBL595253 IC50 6.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3cccc(F)c3)nn2)CC1 CHEMBL589404 IC50 6.0 nM
c1ccc2c(c1)CCC1(CCN(c3ccc(-c4nnc(Cc5ccncc5)o4)nn3)CC1)O2 CHEMBL1276720 IC50 6.0 nM
O=C(Nc1ncc(CCO)s1)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093874 INH 6.0 nM
CNC(=O)c1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127539 IC50 6.0 nM
Cc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)s1 CHEMBL3127652 IC50 6.0 nM
OCc1cnn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)c1 CHEMBL3127644 IC50 6.0 nM
Fc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cc1 CHEMBL3127532 IC50 6.0 nM
Cn1cc(-c2ccc(N3CCC(n4nc(Cl)c5ccccc54)CC3)nn2)cn1 CHEMBL3684115 IC50 6.0 nM
Cc1nc2ccc(NCc3cccc(C(F)(F)F)c3)cc2n(CCNC(=O)CO)c1=O CHEMBL573829 IC50 6.1 nM
O=C(O)CCc1csc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)cc2)n1 CHEMBL4292509 IC50 6.3 nM
O=C(Nc1nc(CCO)cs1)c1ccc(CNc2ccccc2Cl)cc1 CHEMBL4286512 IC50 6.4 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3C)cc2)n1 CHEMBL4284259 IC50 6.4 nM
COc1ccc(-c2nc3ccc(NCc4cc(C(F)(F)F)ccn4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL522160 IC50 6.5 nM
OCc1noc(-c2ccc(N3CCC4(COc5ccccc54)C3)nn2)n1 CHEMBL4075104 IC50 6.5 nM
CC(C)CCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)s1 CHEMBL4280567 IC50 6.7 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccc3)nn2)CC1 CHEMBL595474 IC50 7.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL590374 IC50 7.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccsc3)nn2)CC1 CHEMBL590108 IC50 7.0 nM
NC(=O)c1nnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)s1 CHEMBL1081257 IC50 7.0 nM
O=C(O)c1cncc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nn2)c1 CHEMBL1950397 IC50 7.0 nM
OCc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cc1 CHEMBL3127530 IC50 7.0 nM
COc1ccc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)nc1 CHEMBL3684091 IC50 7.0 nM
O=C(O)Cc1csc(NC(=O)c2ccc(CNc3ccccc3Cc3ccccc3)s2)n1 CHEMBL4288454 IC50 7.5 nM
COc1ccc(C(=O)Nc2nnc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL552052 IC50 8.0 nM
Cc1nc(N2CCN(CCCc3ccccc3)C2=O)sc1C(=O)NCc1cccnc1 CHEMBL3104819 IC50 8.0 nM
Cc1nc(-n2cnn(Cc3ccc(C(F)(F)F)o3)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394690 IC50 8.0 nM
OCc1ccc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3684093 IC50 8.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5ccc(C(F)(F)F)cc54)CC3)nn2)cn1 CHEMBL3684113 IC50 8.0 nM
COCc1cnn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 CHEMBL3684123 IC50 8.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(=O)c4ccccc4)cc3)sc2c1 CHEMBL4638796 IC50 8.0 nM
N[C@H](c1ccccc1)c1ccc(C(=O)Nc2nc3ccc(O)cc3s2)cc1 CHEMBL4647386 IC50 8.0 nM
O=C(Nc1ncc(C(=O)O)s1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4291417 IC50 8.1 nM
COc1ccc(-c2nc3ccc(NCc4ccc(Cl)c(Cl)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL493960 IC50 8.6 nM
O=C(O)Cc1csc(NC(=O)c2ccc(CNc3ccccc3-c3ccccc3)cc2)n1 CHEMBL4278895 IC50 8.7 nM
CCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)s1 CHEMBL4276719 IC50 8.8 nM
CCCc1ccccc1NCc1ccc(C(=O)Nc2nc(C)cs2)cc1 CHEMBL4287688 IC50 8.9 nM
COc1ccc2cc(C(=O)Nc3ncc(Cc4cccc(C(F)(F)F)c4)s3)ccc2c1 CHEMBL564822 IC50 9.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3ccc(F)c(F)c3)s2)cc1OCCO CHEMBL557652 IC50 9.0 nM
O=C(NCCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL591796 IC50 9.0 nM
CCOc1cnn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)c1 CHEMBL3127646 IC50 9.0 nM
Cc1cn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127542 IC50 9.0 nM
Cc1nc(-n2cnn(CCOc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394691 IC50 9.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1nccs1 CHEMBL3393077 IC50 9.0 nM
Cc1cnc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)s1 CHEMBL3684089 IC50 9.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127541 IC50 9.0 nM
O=C(O)Cc1csc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)s2)n1 CHEMBL4285733 IC50 9.0 nM
O=C(Nc1nc2ccccc2s1)c1ccc(C(=O)c2ccccc2)cc1 CHEMBL4632656 IC50 9.0 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3Cl)cc2)n1 CHEMBL4294569 IC50 9.2 nM
N#CC1(c2ccc(S(F)(F)(F)(F)F)cc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4070522 IC50 9.5 nM
Cc1ccc(-c2nc3cnc(NCc4cccc(C(F)(F)F)c4)nc3n(CCC(N)=O)c2=O)cc1 CHEMBL495352 IC50 9.6 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)s2)n1 CHEMBL4281535 IC50 9.7 nM
COc1cc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)ccc1OCCO CHEMBL561073 IC50 10.0 nM
O=C(NCc1cccnc1)Nc1ccc(N2CCC3(CCc4c(cccc4C(F)(F)F)O3)CC2)nn1 CHEMBL606037 IC50 10.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC(C(=O)c3ccccc3OC(F)(F)F)CC2)nn1 CHEMBL600052 IC50 10.0 nM
NC(=O)c1cnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)s1 CHEMBL1080909 IC50 10.0 nM
O=C(NCC(O)c1cccnc1)c1ccc(N2CCC3(CC2)CCN(CC2CC2)c2ccccc2O3)nn1 CHEMBL1774097 IC50 10.0 nM
O=C(NCCCC1CC1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315095 IC50 10.0 nM
Cc1nc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(=O)NCc1cccnc1 CHEMBL3104818 IC50 10.0 nM
CC(=O)Nc1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL552369 IC50 11.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3cccc(F)c3)s2)cc1OCCO CHEMBL559108 IC50 11.0 nM
Cc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cc1 CHEMBL3127656 IC50 11.0 nM
OCCc1cnn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)c1 CHEMBL3127645 IC50 11.0 nM
Cn1cc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127667 IC50 11.0 nM
Cc1cnn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)c1 CHEMBL3127643 IC50 11.0 nM
CNC(=O)Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127651 IC50 11.0 nM
COc1ncc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3684094 IC50 11.0 nM
O=C(O)Cn1nnc(-c2cc(N3CCC4(CCc5c(Cl)cccc5O4)CC3)no2)n1 CHEMBL3952332 IC50 11.0 nM
N#CC1(c2ccc(OC(F)(F)F)cc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4092350 IC50 11.0 nM
N[C@H](c1ccccc1)c1ccc(C(=O)Nc2nc3ccccc3s2)cc1 CHEMBL4635390 IC50 11.0 nM
COc1ccc2nc(NC(=O)c3ccc([C@H](N)c4ccccc4)cc3)sc2c1 CHEMBL4641007 IC50 11.0 nM
O=C(Nc1ncc(Cc2cccc(C(F)(F)F)c2)s1)c1ccc(N2CCOCC2)c(OCCO)c1 CHEMBL550237 IC50 12.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)nn1 CHEMBL2315130 IC50 12.0 nM
Cc1nc(-n2ccc(OCCC3CC3)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104392 IC50 12.0 nM
Cc1cnc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)s1 CHEMBL3127653 IC50 12.0 nM
OCCn1cc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3893904 IC50 12.0 nM
Cn1cc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3127540 IC50 12.0 nM
CN(C)c1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127538 IC50 12.0 nM
Cc1cnn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 CHEMBL3684122 IC50 12.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CC3)CC(=O)c3c(Cl)cccc3O4)s2)n1 CHEMBL3956148 IC50 12.0 nM
CC(=O)NCCn1c(=O)c(-c2cccnc2)nc2ccc(NCc3ccc(F)c(Cl)c3)nc21 CHEMBL495170 IC50 13.0 nM
CC(=O)NCCn1c(=O)c(-c2cccnc2)nc2ccc(NCc3cccc(C(F)(F)F)c3)cc21 CHEMBL494543 IC50 13.0 nM
COc1ccc(-c2nc3ccc(NCc4cccc(C)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494552 IC50 13.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5c(Cl)cccc5O4)CC3)s2)n1 CHEMBL3978089 IC50 13.0 nM
COc1cccc2c1CCC1(CCN(c3nnc(-c4nnn(CC(=O)O)n4)s3)CC1)O2 CHEMBL3937231 IC50 13.0 nM
O=C(O)Cc1csc(NC(=O)c2ccc(CNc3ccccc3Cl)cc2)n1 CHEMBL4280003 IC50 13.0 nM
C#CCOc1ccc2nc(NC(=O)c3ccc(C(=O)c4ccccc4)cc3)sc2c1 CHEMBL4641731 IC50 13.0 nM
NC(=O)c1cc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)no1 CHEMBL1081111 IC50 14.0 nM
Fc1ccc2c(c1)N(C1CCN(c3ccc(-c4ccc(C(F)(F)F)nc4)nn3)CC1)CC2 CHEMBL3127536 IC50 14.0 nM
CN(C)c1ccc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3982961 IC50 14.0 nM
Cc1nsc(-c2ccc(N3CCC(N4CCc5ccccc54)CC3)nn2)n1 CHEMBL3684079 IC50 14.0 nM
OCc1nnc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)o1 CHEMBL3684083 IC50 14.0 nM
Cc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)cc1 CHEMBL4289099 IC50 14.0 nM
CC(=O)NCCn1c(=O)c(-c2cccnc2)nc2ccc(NCc3ccc(Cl)c(Cl)c3)nc21 CHEMBL495001 IC50 15.0 nM
CN(C)c1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL562849 IC50 15.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4cccc(Cl)c4)cc3)[nH]c2c1 CHEMBL1271648 IC50 15.0 nM
O=C(NC[C@H](O)c1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL600886 IC50 15.0 nM
Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127661 IC50 15.0 nM
CNC(=O)Cn1cc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3903911 IC50 15.0 nM
CC(=O)Nc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3684097 IC50 15.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5c(Cl)cccc54)CC3)nn2)cn1 CHEMBL3684102 IC50 15.0 nM
N#CC1(c2cccc(Cl)c2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4074320 IC50 15.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(F)c(C(F)(F)F)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL523668 IC50 16.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(Cl)c(Cl)c4)nc3n(CCC(N)=O)c2=O)cc1 CHEMBL523356 IC50 16.0 nM
O=C(Nc1ncc(Cc2cccc(C(F)(F)F)c2)s1)c1ccc(OCCO)c(OCCO)c1 CHEMBL565065 IC50 16.0 nM
FC(F)(F)c1cccc2c1CCC1(CCN(c3ccc(-c4nnc(CCc5cccnc5)o4)nn3)CC1)O2 CHEMBL593109 IC50 16.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2ncc(-c3ncon3)s2)CC1 CHEMBL1087772 IC50 16.0 nM
O=c1[nH]c(CO)nc2nc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)sc12 CHEMBL1834443 IC50 16.0 nM
O=C(Nc1nc2c(s1)CNCC2)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093860 INH 16.0 nM
Fc1ccc2ccn(C3CCN(c4ccc(-c5ccc(C(F)(F)F)nc5)nn4)CC3)c2c1 CHEMBL3930420 IC50 16.0 nM
Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(C(F)(F)F)cc54)CC3)nn2)cn1 CHEMBL3127666 IC50 16.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5ccc(Cl)cc54)CC3)nn2)cn1 CHEMBL3684109 IC50 16.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)CC(O)c2c(F)cccc2O3)nn1 CHEMBL593353 IC50 17.0 nM
Nc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2s1 CHEMBL1834453 IC50 17.0 nM
O=C(Nc1nc2c(s1)COCC2)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093880 INH 17.0 nM
OCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127649 IC50 17.0 nM
O=C(O)Cn1nnc(-c2cc(N3CCC4(CC3)CC(=O)c3c(Cl)cccc3O4)no2)n1 CHEMBL3984794 IC50 17.0 nM
CCCCCCCCc1ccccc1NCc1ccc(C(=O)Nc2nc(CC(=O)O)cs2)s1 CHEMBL4291877 IC50 17.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cc(Cl)ccc3C(F)(F)F)CC2)nn1 CHEMBL2315132 IC50 18.0 nM
O=C(Nc1nc(CCO)cs1)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093873 INH 18.0 nM
Cc1csc(NC(=O)c2ccc(CNc3cccc(Cl)c3)cc2)n1 CHEMBL4291104 IC50 18.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(=O)NCc4ccccc4)cc3)sc2c1 CHEMBL4641073 IC50 18.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4ccccc4F)nc3)[nH]c2c1 CHEMBL1272148 IC50 19.0 nM
OCn1cc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3933027 IC50 19.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CCc4ccccc4C3=O)CC2)nn1 CHEMBL604995 IC50 20.0 nM
OCCc1cnn(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)c1 CHEMBL3971592 IC50 20.0 nM
Cn1cc(Cl)nc(N2CCC(Oc3cc(F)ccc3Cl)CC2)c1=O CHEMBL3677250 IC50 20.0 nM
N#CC1(c2ccc(Cl)cc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4082092 IC50 20.0 nM
CC(=O)NCCn1c(=O)c(-c2cccnc2)nc2cnc(NCc3ccc(Cl)c(Cl)c3)cc21 CHEMBL495359 IC50 21.0 nM
Cc1nnc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nn2)s1 CHEMBL594902 IC50 21.0 nM
Cc1csc(NC(=O)N2CCC(N3CCc4ccc(F)cc43)CC2)n1 CHEMBL3093868 INH 21.0 nM
Cc1csc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)n1 CHEMBL3684084 IC50 21.0 nM
CCOCCn1cc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3684110 IC50 21.0 nM
Fc1ccc2c(c1)N(C1CCN(c3ccc(-c4cn[nH]c4)nn3)CC1)CC2 CHEMBL3684111 IC50 21.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CC3)Cc3cccc(Cl)c3C(=O)O4)s2)n1 CHEMBL3892584 IC50 21.0 nM
CC(C)(C)c1ccc(C2(C#N)CCN(c3ccc(-c4nc(CO)no4)nn3)CC2)cc1 CHEMBL4071569 IC50 21.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccc3F)nn2)CC1 CHEMBL591563 IC50 22.0 nM
OCc1ccc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cc1 CHEMBL3936465 IC50 22.0 nM
CCCn1cc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3979656 IC50 22.0 nM
O=C(Nc1nc(CO)c(C(=O)O)s1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4293323 IC50 22.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(=O)c4ccccn4)cc3)sc2c1 CHEMBL4636605 IC50 22.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(N)c4ccccc4)cc3)sc2c1 CHEMBL4640753 IC50 22.0 nM
O=C(CNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1)c1ccccc1 CHEMBL2315107 IC50 23.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(=O)c4cccnc4)cc3)sc2c1 CHEMBL4640424 IC50 23.0 nM
NC(=O)c1cnc(N2CCC(Sc3ccccc3C(F)(F)F)CC2)s1 CHEMBL1076688 IC50 24.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4ccccc4)cc3)[nH]c2c1 CHEMBL1271488 IC50 24.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3ccc(F)cc3C(F)(F)F)CC2)nn1 CHEMBL2315412 IC50 24.0 nM
CCCCCCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315100 IC50 24.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CC3)CC(=O)c3c(Cl)cccc3O4)s2)n1 CHEMBL3961032 IC50 24.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3cccs3)nn2)CC1 CHEMBL592754 IC50 25.0 nM
Cc1nc(-n2ccc(OCc3ccccc3)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104389 IC50 26.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 CHEMBL1272304 IC50 27.0 nM
O=C(NCc1cccnc1)c1ccc(N2CCC3(CCc4ccccc4O3)CC2)nn1 CHEMBL1276721 IC50 27.0 nM
O=C(O)Cn1nnc(-c2cc(N3CC4CN(c5cc(F)ccc5Cl)CC4C3)no2)n1 CHEMBL1938871 IC50 27.0 nM
N#CC1(c2ccc(C(F)(F)F)cc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4097690 IC50 27.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3cccnc3)nn2)CC1 CHEMBL604871 IC50 28.0 nM
CCCCCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315099 IC50 28.0 nM
Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(Cl)cc54)CC3)nn2)cn1 CHEMBL3127663 IC50 28.0 nM
O=c1[nH]cnc2nc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)sc12 CHEMBL1834262 IC50 29.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(O)c4ccccn4)cc3)sc2c1 CHEMBL4632847 IC50 29.0 nM
O=C(CNc1nccnc1Cl)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230609 IC50 30.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4cccc(F)c4)cc3)[nH]c2c1 CHEMBL1271700 IC50 30.0 nM
O=C1NCCn2nc(NC(=O)N3CCC(N4CCc5ccc(F)cc54)CC3)cc21 CHEMBL3093863 INH 30.0 nM
Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccc(F)cc1 CHEMBL3104405 IC50 30.0 nM
CCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127647 IC50 30.0 nM
Fc1ccc(Cl)c(OC2CCN(c3nccnn3)CC2)c1 CHEMBL3677254 IC50 30.0 nM
FC(F)(F)c1ccccc1NC1CCN(c2nccnn2)CC1 CHEMBL3677263 IC50 30.0 nM
Cc1csc(NC(=O)N2CCC(CNc3ccccc3C(F)(F)F)CC2)n1 CHEMBL4282929 IC50 30.0 nM
Fc1ccc2c(c1)N(C1CCN(c3ccc(-c4ccc(C(F)(F)F)cc4)nn3)CC1)CC2 CHEMBL3127531 IC50 31.0 nM
CCOC(=O)Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3684099 IC50 31.0 nM
O=C(Nc1nc(CCCO)c(CCO)s1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4293726 IC50 31.0 nM
COc1ccc(C(=O)Nc2cnc(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL563203 IC50 32.0 nM
COc1ccc(NC(=O)c2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL564162 IC50 32.0 nM
Cc1ncc(CNC(=O)c2sc(-n3cnn(Cc4ccc(F)cc4)c3=O)nc2C)s1 CHEMBL3394682 IC50 32.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)CC(O)c2cccc(F)c2O3)nn1 CHEMBL595231 IC50 33.0 nM
COc1ccc(-c2nc3cnc(NCc4ccc(Cl)c(Cl)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL495194 IC50 34.0 nM
Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104401 IC50 34.0 nM
Cc1nsc(-c2ccc(N3CCC(n4ccc5ccccc54)CC3)nn2)n1 CHEMBL3684078 IC50 34.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2c(F)ccc(F)c2Cl)CC1 CHEMBL395048 IC50 35.0 nM
CNc1ccc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3965467 IC50 35.0 nM
Cn1cc(-c2ccc(N3CCC(n4ccc5ccc(Cl)cc54)CC3)nn2)cn1 CHEMBL3895807 IC50 35.0 nM
NC(=O)CCn1c(=O)c(-c2cccnc2)nc2cnc(NCc3ccc(Cl)c(Cl)c3)nc21 CHEMBL494828 IC50 36.0 nM
CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL229212 IC50 37.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2c(Cl)cccc2Cl)CC1 CHEMBL230823 IC50 38.0 nM
Cn1nc(Cc2cccnc2)nc1-c1ccc(N2CCC3(CCc4c(cccc4C(F)(F)F)O3)CC2)nn1 CHEMBL594051 IC50 38.0 nM
OCc1noc(-c2ccc(N3CCC(c4ccccc4)(C(F)(F)F)CC3)nn2)n1 CHEMBL4084609 IC50 38.0 nM
COC(=O)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230501 IC50 39.0 nM
CCNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL231635 IC50 39.0 nM
Cc1nc(-c2cnc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)s2)no1 CHEMBL1087014 IC50 39.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL572098 IC50 39.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cocn1 CHEMBL3394680 IC50 39.0 nM
CC(=O)NCCn1c(=O)c(-c2ccc(C)cc2)nc2cnc(NCc3ccc(Cl)c(Cl)c3)cc21 CHEMBL522883 IC50 40.0 nM
CC(C)N1CCC2(CCN(c3ccc(C(=O)NCC(O)c4cccnc4)nn3)CC2)Oc2ccccc21 CHEMBL1774095 IC50 40.0 nM
Cc1nc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(=O)NCc1ccccn1 CHEMBL3104825 IC50 40.0 nM
O=C(O)Cn1nnc(-c2cc(OCCCOc3cc(F)ccc3Br)no2)n1 CHEMBL1950546 IC50 41.0 nM
O=C(NCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315104 IC50 41.0 nM
CCOCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127650 IC50 41.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CC3)CC(=O)c3ccccc3O4)s2)n1 CHEMBL3959246 IC50 41.0 nM
O=C(Nc1nc(CO)cs1)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093871 INH 42.0 nM
O=C(Nc1nc2ccccc2[nH]1)c1ccc(C(=O)c2ccccc2)cc1 CHEMBL4648170 IC50 42.0 nM
COc1ccc2nc(NC(=O)c3ccc(OCc4ccccc4)cc3)sc2c1 CHEMBL4639169 IC50 43.0 nM
COc1ccc2nc(NC(=O)c3ccc(Nc4ccccc4)cc3)sc2c1 CHEMBL4633256 IC50 44.0 nM
Cc1nc(-n2cnn(Cc3ccc(C(F)(F)F)cc3)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394688 IC50 46.0 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3C)cn2)n1 CHEMBL4287295 IC50 46.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(F)c(Cl)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494031 IC50 47.0 nM
COc1ccc(-c2nc3ccc(NCc4cccc(C(F)(F)F)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494032 IC50 47.0 nM
Fc1ccc(Br)c(OC2CCN(c3ncc4nc[nH]c4n3)CC2)c1 CHEMBL1834452 IC50 47.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2ncnc3[nH]cnc23)CC1 CHEMBL1834454 IC50 48.0 nM
Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccc(F)c(F)c1 CHEMBL3104407 IC50 48.0 nM
O=C(CO)Nc1cnc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1 CHEMBL467091 IC50 49.0 nM
NC(=O)c1cnc(NC(=O)N2CCC(N3CCc4ccc(F)cc43)CC2)s1 CHEMBL3093876 INH 49.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5ccccc54)CC3)s2)n1 CHEMBL3928242 IC50 49.0 nM
Cc1nc(-n2ccc(CCc3ccccc3)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104390 IC50 50.0 nM
CCCOc1ccc2nc(NC(=O)c3ccc(C(=O)c4ccccc4)cc3)sc2c1 CHEMBL4640865 IC50 50.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2c(F)cccc2Cl)CC1 CHEMBL395074 IC50 51.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL231534 IC50 51.0 nM
COc1ccc(-c2nc3ccc(NCc4cc(C(F)(F)F)cc(C(F)(F)F)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL522492 IC50 51.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5c(C(F)(F)F)cccc54)CC3)nn2)cn1 CHEMBL3684112 IC50 52.0 nM
OCc1cnn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 CHEMBL3684120 IC50 52.0 nM
O=C(O)COc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2s1 CHEMBL1834456 IC50 53.0 nM
Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104608 IC50 53.0 nM
OCCn1cc(-c2ccc(N3CCC(n4ncc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3684114 IC50 53.0 nM
Cc1csc(NC(=O)N2CCC(c3noc4ccc(F)cc34)CC2)n1 CHEMBL3093869 INH 54.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2ncc(-c3ncco3)s2)CC1 CHEMBL1081996 IC50 55.0 nM
Cc1nc(-n2ccc(OCc3cscn3)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104394 IC50 55.0 nM
Cc1nc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(N)=O CHEMBL3104606 IC50 55.0 nM
Fc1cc(Br)c(OC2CCN(c3nccnn3)CC2)cc1F CHEMBL3677261 IC50 55.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Br)CC1 CHEMBL230821 IC50 58.0 nM
O=C(O)Cc1cnc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)cc2)s1 CHEMBL4293987 IC50 58.0 nM
COc1ccc2nc(NC(=O)c3ccc(N)cc3)sc2c1 CHEMBL4637153 IC50 58.0 nM
Cc1nc2nc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)sc2c(=O)[nH]1 CHEMBL1834442 IC50 59.0 nM
NNC(=O)c1ccc(N2CCC(c3noc4ccc(F)cc34)CC2)nn1 CHEMBL3688829 IC50 59.0 nM
COC1CC2(CCN(c3ccc(C(=O)NCC(O)c4ccccc4)nn3)CC2)Oc2ccccc21 CHEMBL594083 IC50 60.0 nM
CS(=O)(=O)c1ccn2cc(-c3ccc(-c4ccccc4)cc3)nc2c1 CHEMBL1272204 IC50 60.0 nM
O=C(NC[C@@H](O)c1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL602933 IC50 60.0 nM
OCCc1cnn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 CHEMBL3684124 IC50 60.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(C=Cc4ccccc4O3)CC2)nn1 CHEMBL603419 IC50 61.0 nM
COc1ccn(-c2nc(C)c(C(=O)NCc3ccccc3)s2)c(=O)c1 CHEMBL3104391 IC50 61.0 nM
Cc1cc(C(=O)N2CCN(c3ccc(C(=O)NCCC4CC4)nn3)CC2)c(C(F)(F)F)o1 CHEMBL2315124 IC50 62.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CC3)NC(=O)c3c(Cl)cccc3O4)s2)n1 CHEMBL3920582 IC50 62.0 nM
Cc1nc(N2CCN(CC3CC3)C2=O)sc1C(=O)NCc1cccnc1 CHEMBL3104822 IC50 63.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2ncc(-c3nnco3)s2)CC1 CHEMBL1081997 IC50 65.0 nM
O=[N+]([O-])c1ccc(Cl)c(OC2CCN(c3nccnn3)CC2)c1 CHEMBL3677260 IC50 65.0 nM
Cc1cn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3684117 IC50 65.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CC3)COc3ccccc34)s2)n1 CHEMBL3950546 IC50 65.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cccc(F)c3C(F)(F)F)CC2)nn1 CHEMBL2315137 IC50 66.0 nM
Cc1nc(-n2cnn(C(C)c3ccc(F)cc3)c2=O)sc1C(=O)NCc1ccccn1 CHEMBL3394696 IC50 66.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1ccccn1 CHEMBL3394676 IC50 67.0 nM
O=C(COc1ccccc1)Nc1ccc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1 CHEMBL466720 IC50 68.0 nM
Cc1nc2ccc(NCc3cccc(C(F)(F)F)c3)cc2n(CCNC(=O)C(O)CO)c1=O CHEMBL577141 IC50 68.0 nM
Cc1ccc(CNC(=O)c2ccc(N3CCN(C(=O)c4ccccc4C(F)(F)F)CC3)nn2)o1 CHEMBL2315115 IC50 68.0 nM
Cc1nsc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)n1 CHEMBL3684077 IC50 68.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5c(F)cccc54)CC3)nn2)cn1 CHEMBL3684106 IC50 68.0 nM
O=C(Nc1nc2ccccc2[nH]1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315110 IC50 70.0 nM
CCn1cc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3684081 IC50 70.0 nM
COc1ccc2nc(NC(=O)c3ccc([C@@H](N)c4ccccc4)cc3)sc2c1 CHEMBL4636558 IC50 70.0 nM
CCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3127648 IC50 72.0 nM
NS(=O)(=O)c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 CHEMBL1272202 IC50 74.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)Cc2ccccc2CO3)nn1 CHEMBL593352 IC50 76.0 nM
O=C(Nc1nc2c(s1)CCCC2)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093879 INH 76.0 nM
Cc1cn(-c2ccc(N3CCC(N4CCc5ccccc54)CC3)nn2)cn1 CHEMBL3684076 IC50 76.0 nM
O=C(CO)Nc1ccc2ncn(Cc3ccc(Cl)cc3)c(=O)c2c1 CHEMBL466257 IC50 79.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC(C(=O)c3ccc(F)cc3)CC2)nn1 CHEMBL589379 IC50 80.0 nM
N#CC1(c2ccccc2Cl)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4101065 IC50 80.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(Cl)c(Cl)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL495191 IC50 81.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3ccc(C)c(F)c3)s2)cc1OCCO CHEMBL561530 IC50 82.0 nM
NC(=O)c1cnc(N2CC[C@H](Oc3ccccc3C(F)(F)F)C2)s1 CHEMBL1081255 IC50 84.0 nM
Cc1cn(-c2ccc(N3CCC(n4ccc5ccccc54)CC3)nn2)cn1 CHEMBL3684118 IC50 86.0 nM
Cn1ccc(NC(=O)c2cn(Cc3cccc(OC(F)(F)F)c3)cn2)n1 CHEMBL1683576 IC50 88.0 nM
NC(=O)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL395735 IC50 90.0 nM
NC(=O)CCn1c(=O)c(-c2cccnc2)nc2cnc(NCc3cccc(C(F)(F)F)c3)nc21 CHEMBL524169 IC50 92.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5ccccc54)CC3)nn2)cn1 CHEMBL3684095 IC50 92.0 nM
NC(=O)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL397451 IC50 94.0 nM
Cc1nc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C(=O)NCc1ncco1 CHEMBL3104605 IC50 95.0 nM
COc1ncc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)cn1 CHEMBL3684092 IC50 95.0 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3)cc2)n1 CHEMBL4292656 IC50 95.0 nM
COc1ccc(-c2nc3ccc(NCc4cccc(C)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL493929 IC50 96.0 nM
C[S+]([O-])c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 CHEMBL1272256 IC50 96.0 nM
CNC(=O)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL231335 IC50 97.0 nM
O=C(NCc1cccnc1)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL395287 IC50 99.0 nM
O=C(NCCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nc1 CHEMBL589378 IC50 99.0 nM
Cn1cc(-c2ccc(N3CCC(N4CCc5cc(F)ccc54)CC3)nn2)cn1 CHEMBL3127660 IC50 99.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Nc2ccccc2C(F)(F)F)CC1 CHEMBL230175 IC50 100.0 nM
O=C(NCCO)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL395050 IC50 100.0 nM
COc1ccc(-c2nc3ccc(NCc4cccc(Cl)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494023 IC50 100.0 nM
CCN1CCC2(CCN(c3ccc(C(=O)NCC(O)c4cccnc4)nn3)CC2)Oc2ccccc21 CHEMBL1774094 IC50 100.0 nM
O=C(NCCCCC1CC1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315096 IC50 100.0 nM
CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nc1 CHEMBL2315089 IC50 100.0 nM
Cn1ccnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)c1=O CHEMBL3677249 IC50 100.0 nM
FC(F)(F)c1ccc(Cl)c(OC2CCN(c3nccnn3)CC2)c1 CHEMBL3677253 IC50 100.0 nM
Cc1cnnc(N2CCC(Oc3cc(F)ccc3Cl)CC2)n1 CHEMBL3677256 IC50 100.0 nM
Cc1cnc(N2CCC(Oc3cc(F)ccc3Cl)CC2)nn1 CHEMBL3677259 IC50 100.0 nM
N#CC1(c2ccc([N+](=O)[O-])cc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4100103 IC50 100.0 nM
C#CCNC(=O)c1ccc(C(=O)Nc2nc3ccc(OC)cc3s2)cc1 CHEMBL4643557 IC50 100.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cc(Cl)ccc3Cl)CC2)nn1 CHEMBL2315135 IC50 101.0 nM
O=C(NCc1cccnc1)c1cc(-n2cnn(Cc3ccc(F)cc3)c2=O)n[nH]1 CHEMBL3394697 IC50 103.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cc[nH]n1 CHEMBL3394683 IC50 105.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC(C(=O)c3ccccc3)CC2)nn1 CHEMBL591100 IC50 108.0 nM
Cc1cnc(NC(=O)N2CCC(N3CCc4ccc(F)cc43)CC2)s1 CHEMBL3093870 INH 108.0 nM
O=C(NCc1ccncc1)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230289 IC50 110.0 nM
O=C(NCc1ccccn1)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230180 IC50 110.0 nM
CCNC(=O)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL231336 IC50 110.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(Cl)cc4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL495356 IC50 110.0 nM
O=C(CO)Nc1ccc2ncn(Cc3ccc(Cl)c(C(F)(F)F)c3)c(=O)c2c1 CHEMBL466674 IC50 110.0 nM
COC1(c2ccccc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4062944 IC50 110.0 nM
Fc1ccc2onc(C3CCN(c4ccc(-c5cn[nH]c5)nn4)CC3)c2c1 CHEMBL3684087 IC50 111.0 nM
CS(=O)(=O)c1cnc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 CHEMBL1272042 IC50 113.0 nM
O=C(CO)N1CCc2nc(NC(=O)N3CCC(N4CCc5ccc(F)cc54)CC3)sc2C1 CHEMBL3093862 INH 113.0 nM
Cc1csc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 CHEMBL3684088 IC50 114.0 nM
O=C(CO)Nc1ccc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1 CHEMBL444433 IC50 119.0 nM
CC(C(=O)N1CCN(c2ccc(C(=O)NCCC3CC3)nn2)CC1)(C(F)(F)F)C(F)(F)F CHEMBL2315118 IC50 119.0 nM
O=C(NCCO)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL397450 IC50 120.0 nM
CNC(=O)CCn1c(=O)c(-c2ccc(OC)cc2)nc2ccc(NCc3cccc(C(F)(F)F)c3)nc21 CHEMBL493139 IC50 120.0 nM
CC(=O)NCCn1c(=O)c(-c2cccnc2)nc2ccc(NCc3cccc(C(F)(F)F)c3)nc21 CHEMBL521865 IC50 120.0 nM
COc1ccc2nc(NC(=O)c3ccc(N=[N+]=[N-])cc3)sc2c1 CHEMBL4641596 IC50 120.0 nM
Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCCc1ccc(F)cc1 CHEMBL3104408 IC50 121.0 nM
Cc1ccc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)s1 CHEMBL3908520 IC50 121.0 nM
O=C(NCc1ccc(C(F)(F)F)o1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315116 IC50 124.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3cc(Cl)ccc3Cl)s2)cc1OCCO CHEMBL556495 IC50 125.0 nM
O=C(NCCCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315105 IC50 125.0 nM
O=C(Nc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315103 IC50 125.0 nM
Cc1nc(-n2cnn(Cc3cc(F)cc(F)c3)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394689 IC50 125.0 nM
Cn1cc(-c2ccc(N3CCC(n4ccc5ccccc54)CC3)nn2)cn1 CHEMBL3127658 IC50 126.0 nM
Cc1ccn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)n1 CHEMBL3684121 IC50 126.0 nM
O=C(O)c1ccc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nn2)nc1 CHEMBL1950401 IC50 128.0 nM
COc1ccc(-c2nc3ccc(NCc4ccc(C)c(C)c4)cc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494747 IC50 130.0 nM
OCc1noc(-c2ccc(N3CCC(O)(c4ccccc4)CC3)nn2)n1 CHEMBL4072613 IC50 130.0 nM
C#CCOc1ccc(C(=O)c2ccc(C(=O)Nc3nc4ccc(OC)cc4s3)cc2)cc1 CHEMBL4645777 IC50 130.0 nM
Cc1nc(N2CCN(CC3CCCCC3)C2=O)sc1C(=O)NCc1cccnc1 CHEMBL3104820 IC50 135.0 nM
Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1cccc(F)c1 CHEMBL3104406 IC50 137.0 nM
O=C(NCc1ccccc1)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL231131 IC50 140.0 nM
COc1ccc(-c2nc3cnc(NCc4ccc(Cl)c(Cl)c4)nc3n(CCC(N)=O)c2=O)cc1 CHEMBL494598 IC50 140.0 nM
Cc1nc(-n2cnn(CC3CC3)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394692 IC50 140.0 nM
O=C(Nc1nc2ccccc2s1)c1ccc([N+](=O)[O-])cc1 CHEMBL4641864 IC50 140.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccncc3)nn2)CC1 CHEMBL591805 IC50 144.0 nM
COc1ccc(C(=O)Nc2ccc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL563632 IC50 145.0 nM
COc1ccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OC CHEMBL562988 IC50 145.0 nM
Cn1cc(-c2ccc(N3CCC(n4ncc5cc(F)ccc54)CC3)nn2)cn1 CHEMBL3684108 IC50 145.0 nM
Cc1csc(NC(=O)c2ccc(COc3ccccc3Cl)cc2)n1 CHEMBL4286168 IC50 150.0 nM
NC(=O)c1cnc(N2CCN(Cc3ccccc3C(F)(F)F)CC2)s1 CHEMBL1080559 IC50 153.0 nM
O=C(Nc1ncc(CO)s1)N1CCC(N2CCc3ccc(F)cc32)CC1 CHEMBL3093872 INH 154.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)CC(O)c2ccc(F)cc2O3)nn1 CHEMBL596578 IC50 156.0 nM
Fc1ccc2onc(C3CCN(c4ccc(-n5ccnc5)nn4)CC3)c2c1 CHEMBL3684116 IC50 156.0 nM
O=C(NCc1ccc(Cl)s1)c1ccc2[nH]c(-c3ccc(C(=O)c4ccccc4C(F)(F)F)cc3)nc2c1 CHEMBL2334643 IC50 157.0 nM
Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1ccccn1 CHEMBL3104824 IC50 158.0 nM
COc1ccc2nc(NC(=O)c3ccc([N+](=O)[O-])cc3)sc2c1 CHEMBL4648521 IC50 160.0 nM
Nc1ncnc2[nH]c(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc12 CHEMBL1834447 IC50 162.0 nM
Fc1ccc2onc(C3CCN(c4ccc(-c5cccnc5)nn4)CC3)c2c1 CHEMBL3684080 IC50 165.0 nM
O=C(O)CNc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2s1 CHEMBL1834457 IC50 168.0 nM
Cc1cc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)ccn1 CHEMBL3684086 IC50 171.0 nM
Cn1cc(-c2ccc(N3CCC(n4ccc5ccc(C(F)(F)F)cc54)CC3)nn2)cn1 CHEMBL3962327 IC50 173.0 nM
O=C1CCCN1c1cnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)s1 CHEMBL1081113 IC50 174.0 nM
O=C(NCc1nccs1)c1ccc2[nH]c(-c3ccc(C(=O)c4ccccc4C(F)(F)F)cc3)nc2c1 CHEMBL2334642 IC50 179.0 nM
COc1ccc(-c2nc3ccc(NCc4cc(C(F)(F)F)ccn4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL492498 IC50 180.0 nM
O=C(CO)Nc1ccc2c(=O)n(Cc3ccc(Cl)c(Cl)c3)cnc2c1 CHEMBL512969 IC50 180.0 nM
Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccn3)nn2)CC1 CHEMBL589380 IC50 180.0 nM
Cn1cc(-c2ccc(N3CCC(n4ccc5cc(Cl)ccc54)CC3)nn2)cn1 CHEMBL3894972 IC50 181.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(CC3)NC(=O)c3ccccc3O4)s2)n1 CHEMBL3984902 IC50 181.0 nM
Cc1ncc2sc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc2n1 CHEMBL1834446 IC50 182.0 nM
N#CC1(c2ccccc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4083088 IC50 190.0 nM
Cc1ccn(-c2nc(C)c(C(=O)NCc3ccccc3)s2)c(=O)c1 CHEMBL3104396 IC50 191.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3cc(F)ccc3Cl)CC2)nn1 CHEMBL2315129 IC50 192.0 nM
O=C(Nc1ccc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1)OCc1ccccc1 CHEMBL466313 IC50 193.0 nM
Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1ccc(F)cc1 CHEMBL3104815 IC50 194.0 nM
Cc1cnc(CNC(=O)c2sc(-n3cnn(Cc4ccc(F)cc4)c3=O)nc2C)cn1 CHEMBL3394679 IC50 194.0 nM
NC(=O)c1nnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)o1 CHEMBL1081258 IC50 199.0 nM
Cn1cc(Cl)nc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)c1=O CHEMBL3677246 IC50 200.0 nM
Cn1cc(Cl)nc(N2CCC(Oc3cc(C(F)(F)F)ccc3Cl)CC2)c1=O CHEMBL3677247 IC50 200.0 nM
Cn1nccc(N2CCC(Oc3cc(C(F)(F)F)ccc3Cl)CC2)c1=O CHEMBL3677266 IC50 200.0 nM
CNC(=O)c1cnc(NC(=O)N2CCC(N3CCc4ccc(F)cc43)CC2)s1 CHEMBL3093878 INH 206.0 nM
O=Cc1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230503 IC50 210.0 nM
COc1ccc(-c2nc3ccc(NCc4cccc(OC(F)(F)F)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL493134 IC50 210.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1ncco1 CHEMBL3394681 IC50 214.0 nM
Cc1c(C(=O)N=C(N)N)ncn1Cc1ccc(Cl)cc1 CHEMBL1683575 IC50 217.0 nM
Cn1cc(-c2ccc(N3CCC(N4CCc5cc(Cl)ccc54)CC3)nn2)cn1 CHEMBL3127662 IC50 218.0 nM
Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1cccc(F)c1 CHEMBL3102878 IC50 219.0 nM
O=C(Nc1ccc2ncn(Cc3ccc(F)c(Cl)c3)c(=O)c2c1)OCc1ccccc1 CHEMBL466314 IC50 220.0 nM
NC1(c2ccccc2)CCN(c2ccc(-c3nc(CO)no3)nn2)CC1 CHEMBL4093327 IC50 220.0 nM
Cc1nc(-n2cnn(Cc3ccc(C(F)(F)F)cc3)c2=O)sc1C(=O)NCc1ccccn1 CHEMBL3394695 IC50 227.0 nM
O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(CC2)Cc2ccccc2C(=O)O3)nn1 CHEMBL593122 IC50 230.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4cccs4)cc3)[nH]c2c1 CHEMBL1271988 IC50 231.0 nM
Cc1nc(-c2n[nH]c(Cc3ccccc3)n2)sc1C(=O)NCc1ccccc1 CHEMBL3104812 IC50 236.0 nM
Cc1ccc2c(c1)N(C1CCN(c3ccc(-c4cnn(C)c4)nn3)CC1)CC2 CHEMBL3127664 IC50 241.0 nM
O=C(O)Cn1nnc(-c2cnc(N3CCC4(C=Cc5ccccc54)CC3)s2)n1 CHEMBL3922823 IC50 244.0 nM
CC(=O)NCCn1c(=O)c(-c2cccnc2)nc2cnc(NCc3ccc(Cl)c(Cl)c3)nc21 CHEMBL494827 IC50 250.0 nM
O=C(Nc1ccc2ncn(Cc3ccc(Cl)cc3)c(=O)c2c1)OCc1ccccc1 CHEMBL512775 IC50 250.0 nM
O=C(NCCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cn1 CHEMBL590592 IC50 250.0 nM
NC(=O)c1cnc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)s1 CHEMBL576820 IC50 254.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4ccccc4Cl)cc3)[nH]c2c1 CHEMBL1271759 IC50 255.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2ncc3nc[nH]c3n2)CC1 CHEMBL1834451 IC50 257.0 nM
Cc1cn(-c2ccc(N3CCC(c4noc5cc(F)ccc45)CC3)nn2)cn1 CHEMBL3684119 IC50 257.0 nM
CC(C)CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230066 IC50 260.0 nM
O=C(Nc1ncc(CCCO)s1)c1ccc(CNc2ccccc2C(F)(F)F)cc1 CHEMBL4285491 IC50 260.0 nM
O=C(Nc1nc2ccccc2s1)c1cccnc1 CHEMBL4635316 IC50 260.0 nM
O=c1[nH]ccc2nc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)sc12 CHEMBL1834441 IC50 268.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394675 IC50 268.0 nM
COc1ccc2sc(NC(=O)c3ccc([N+](=O)[O-])cc3)nc2c1 CHEMBL499832 IC50 270.0 nM
Fc1ccc2c(c1)N(C1CCN(c3ccc(-c4cnn(CCN5CCOCC5)c4)nn3)CC1)CC2 CHEMBL3684107 IC50 275.0 nM
CN1CCC2(CCN(c3ccc(C(=O)NCC(O)c4ccccc4)nn3)CC2)Oc2ccccc21 CHEMBL1774092 IC50 280.0 nM
Cc1cc(CNC(=O)c2sc(-n3cnn(Cc4ccc(F)cc4)c3=O)nc2C)[nH]n1 CHEMBL3394684 IC50 280.0 nM
Cc1ccc2ccn(C3CCN(c4ccc(-c5cnn(C)c5)nn4)CC3)c2c1 CHEMBL3949127 IC50 286.0 nM
O=C(NCCC1CC1)c1ccc(N2CCN(C(=O)c3ccoc3C(F)(F)F)CC2)nn1 CHEMBL2315122 IC50 290.0 nM
OC(c1ccc2[nH]c(-c3ccc(OCc4ccccc4)cc3)nc2c1)c1ccccc1C(F)(F)F CHEMBL2334628 IC50 295.0 nM
CCCCCCCCC1=C(CCCCCCCC(=O)O)C1 CHEMBL3677268 IC50 300.0 nM
Cc1cnnc(N2CCC(Oc3cc(C(F)(F)F)ccc3Cl)CC2)n1 CHEMBL3677257 IC50 300.0 nM
Cc1nc(-n2cnn(CC3CC3(F)F)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394693 IC50 306.0 nM
Cc1csc(NC(=O)c2ccc(CNc3ccccc3C)nc2)n1 CHEMBL4286944 IC50 310.0 nM
COc1cccc(C(=O)Nc2nc3ccc(OC)cc3s2)c1 CHEMBL4633446 IC50 310.0 nM
COc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccc3)nn2)CC1 CHEMBL591562 IC50 311.0 nM
O=C(NCc1nccs1)c1ccc2[nH]c(-c3ccc(Oc4ccccc4C(F)(F)F)cc3)nc2c1 CHEMBL2334635 IC50 313.0 nM
Cc1nnc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)o1 CHEMBL3684082 IC50 315.0 nM
COc1ccc2ccn(C3CCN(c4ccc(-c5cnn(C)c5)nn4)CC3)c2c1 CHEMBL3928204 IC50 317.0 nM
Oc1nc2cnc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc2[nH]1 CHEMBL1834449 IC50 319.0 nM
O=C(NCc1nccs1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 CHEMBL2315112 IC50 325.0 nM
Cc1nc(-n2ccc(OCC3CCCO3)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104393 IC50 329.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CC3)Cc3ccccc3C(=O)O4)s2)n1 CHEMBL3966966 IC50 338.0 nM
N#Cc1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230608 IC50 340.0 nM
CS(=O)(=O)c1ccc2nc(-c3ccc(-c4cccc(O)c4)cc3)[nH]c2c1 CHEMBL1271699 IC50 342.0 nM
O=C(O)c1ccc(-c2ccc(N3CCC(n4ccc5ccc(F)cc54)CC3)nn2)cc1 CHEMBL3897975 IC50 349.0 nM
O=C(NCc1ccncc1)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL231434 IC50 350.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CCc5c(O)cccc5O4)CC3)s2)n1 CHEMBL3969130 IC50 366.0 nM
O=c1[nH]c(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nc2[nH]cnc12 CHEMBL1834448 IC50 378.0 nM
NC(=O)Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 CHEMBL3684105 IC50 387.0 nM
CCCNC(=O)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL395736 IC50 390.0 nM
O=C(O)c1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cc1 CHEMBL3127533 IC50 390.0 nM
Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(CO)cc54)CC3)nn2)cn1 CHEMBL3684075 IC50 394.0 nM
Cc1nc(-n2cnn(CCCC(F)(F)F)c2=O)sc1C(=O)NCc1cccnc1 CHEMBL3394694 IC50 398.0 nM
COc1ccc2c(c1)N(C1CCN(c3ccc(-c4cnn(C)c4)nn3)CC1)CC2 CHEMBL3127665 IC50 407.0 nM
COc1ccc(-c2nc3cnc(NCc4ccc(Cl)c(Cl)c4)nc3n(CCNC(C)=O)c2=O)cc1 CHEMBL494750 IC50 410.0 nM
O=C(NCc1cccnc1)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL231433 IC50 430.0 nM
O=C(NCc1ccc(Cl)s1)c1ccc2[nH]c(-c3ccc(Oc4ccccc4C(F)(F)F)cc3)nc2c1 CHEMBL2334636 IC50 439.0 nM
Cc1nc(-n2ccc(C3CC3)cc2=O)sc1C(=O)NCc1ccccc1 CHEMBL3104397 IC50 458.0 nM
CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2c(F)cccc2F)CC1 CHEMBL231423 IC50 470.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cnn(C)c1 CHEMBL3394685 IC50 477.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cn(C)cn1 CHEMBL3394686 IC50 504.0 nM
Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1cccnc1 CHEMBL3104817 IC50 524.0 nM
O=C(Nc1ccccc1)c1nccnc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL230290 IC50 550.0 nM
O=C(O)c1ccc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nn2)cc1 CHEMBL1950269 IC50 550.0 nM
Cn1cc(Cl)nc(N2CCC(Oc3ccccc3Cl)CC2)c1=O CHEMBL3677245 IC50 550.0 nM
Cc1ccccc1OC1CCN(c2nc(Cl)cn(C)c2=O)CC1 CHEMBL3677248 IC50 550.0 nM
Clc1ccccc1OC1CCN(c2nccnn2)CC1 CHEMBL3677251 IC50 550.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2nccnn2)CC1 CHEMBL3677252 IC50 550.0 nM
Cc1nnc(N2CCC(Oc3cc(C(F)(F)F)ccc3Cl)CC2)nc1C CHEMBL3677255 IC50 550.0 nM
O=[N+]([O-])c1ccccc1OC1CCN(c2nccnn2)CC1 CHEMBL3677262 IC50 550.0 nM
CC1CN(c2nccnn2)CCC1Oc1cc(C(F)(F)F)ccc1Cl CHEMBL3677264 IC50 550.0 nM
COc1ccc2nc(NC(=O)c3ccc(C(=O)N4CCCCC4)cc3)sc2c1 CHEMBL4648314 IC50 550.0 nM
O=C(NCc1ccccc1)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL231130 IC50 560.0 nM
O=C(O)CCc1cnc(NC(=O)c2ccc(CNc3ccccc3C(F)(F)F)cc2)s1 CHEMBL4286081 IC50 570.0 nM
O=C(NCc1ccccc1)c1ccccc1NCC(=O)N1CCC(Oc2ccccc2Cl)CC1 CHEMBL397194 IC50 580.0 nM
O=C(NCC(O)c1cccnc1)c1ccc(N2CCC3(CC2)CCN(CCO)c2ccccc2O3)nn1 CHEMBL1774098 IC50 600.0 nM
COc1cc2sc(NC(=O)c3ccc(C(=O)c4ccccc4)cc3)nc2cc1Br CHEMBL4646942 IC50 610.0 nM
Cc1nc(-c2cncc(Cc3ccccc3)n2)sc1C(=O)NCc1ccccc1 CHEMBL3104814 IC50 618.0 nM
Cc1cnnc(N2CCC(Oc3ccccc3Cl)CC2)n1 CHEMBL3677258 IC50 650.0 nM
CC1CN(c2nccnn2)CCC1Oc1cc(Cl)ccc1Cl CHEMBL3677265 IC50 650.0 nM
FC(F)(F)c1ccc(Cl)c(OC2CCN(c3nccnn3)C2)c1 CHEMBL3677267 IC50 650.0 nM
Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1ccncc1 CHEMBL3104816 IC50 656.0 nM
CC(CNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1)c1ccccc1 CHEMBL2315106 IC50 660.0 nM
Cc1nnc(-c2ccc(N3CCC(Oc4cc(F)ccc4Cl)CC3)nn2)o1 CHEMBL226646 IC50 670.0 nM
Cc1nc(-n2cc(Cc3ccccc3)nn2)sc1C(=O)NCc1ccccc1 CHEMBL3104614 IC50 675.0 nM
Cn1cc(-c2ccc(N3CCC(n4ccc5c(F)cccc54)CC3)nn2)cn1 CHEMBL3949275 IC50 678.0 nM
CN1CCC2(CCN(c3ccc(C(=O)NCC(O)c4cccnc4)nn3)CC2)Oc2ccccc21 CHEMBL1774093 IC50 700.0 nM
O=C(Nc1nc2ccccc2s1)c1ccc(-c2ccccc2)cc1 CHEMBL4649153 IC50 700.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC4(CC3)CC(=O)c3ccccc3O4)s2)n1 CHEMBL3945992 IC50 708.0 nM
O=C(NCc1ccccn1)c1cc(-n2cnn(Cc3ccc(F)cc3)c2=O)n[nH]1 CHEMBL3394698 IC50 720.0 nM
Cc1cccc(C(=O)Nc2nc3ccccc3s2)c1 CHEMBL4648961 IC50 730.0 nM
CC(C)(C)c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 CHEMBL1272145 IC50 731.0 nM
CCCCN1CCN(c2nc(C)c(C(=O)NCc3cccnc3)s2)C1=O CHEMBL3104823 IC50 748.0 nM
FC(F)(F)c1ccccc1OC1CCN(c2nc3ncccc3s2)CC1 CHEMBL1834445 IC50 755.0 nM
NC(=O)c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1 CHEMBL1915543 IC50 760.0 nM
Cc1csc(NC(=O)c2ccc(CNc3ccc(Cl)cc3)cc2)n1 CHEMBL4280991 IC50 760.0 nM
COC(=O)Nc1cnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)s1 CHEMBL1081826 IC50 775.0 nM
O=C(NCCc1ccccc1)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 CHEMBL231435 IC50 780.0 nM
O=C(O)Cc1cncc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nn2)c1 CHEMBL1950402 IC50 780.0 nM
Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCCC1CC1 CHEMBL3104414 IC50 783.0 nM
Cc1ccc(Cn2cnc3ccc(NC(=O)OCc4ccccc4)cc3c2=O)cc1C CHEMBL466719 IC50 790.0 nM
O=C(NCCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1 CHEMBL591573 IC50 820.0 nM
COc1ccc(C(=O)N(C)c2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL552458 IC50 828.0 nM
COc1ccc(C(=O)Nc2ncc(C(O)c3cccc(C(F)(F)F)c3)s2)cc1OCCO CHEMBL550785 IC50 884.0 nM
COc1ccc2nc(NC(=O)c3ccc(F)cc3)sc2c1 CHEMBL1380535 IC50 900.0 nM
O=C(O)Cn1nnc(-c2nnc(N3CCC(Oc4cc(F)ccc4Br)CC3)s2)n1 CHEMBL2153601 IC50 904.0 nM
COc1cccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)c1 CHEMBL562737 IC50 915.0 nM
Cn1cc(-c2ccc(N3CCC(n4nnc5ccccc54)CC3)nn2)cn1 CHEMBL3684098 IC50 939.0 nM
Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(N)=O CHEMBL3394687 IC50 945.0 nM
O=C(O)Cn1nnc(-c2cnc(OCCCOc3cc(OC(F)(F)F)ccc3Br)s2)n1 CHEMBL1950551 IC50 969.0 nM