Cc1nc(N2CCCC(F)(F)CC2)c(C(=O)Nc2ccnc(S(N)(=O)=O)c2)cc1Cl CHEMBL4760292 IC50 0.3 nM
COc1cc(Oc2ccc(OC(F)(F)F)c(F)c2OC)c(C(=O)Nc2ccnc(C(N)=O)c2)c(F)c1C(F)(F)F CHEMBL4798938 IC50 0.4 nM
Cc1nc(N2CCCC(F)(F)CC2)c(C(=O)Nc2ccnc(S(N)(=O)=O)c2)cc1C(F)(F)F CHEMBL4777598 IC50 0.5 nM
COc1c(Oc2cc(C(F)(F)F)c(C)c(F)c2C(=O)Nc2ccnc(C(N)=O)c2)ccc(OC(F)(F)F)c1F CHEMBL4753280 IC50 0.8 nM
NS(=O)(=O)c1cc(NC(=O)c2ccc(CC3CC3)nc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4781110 IC50 0.9 nM
CCOc1ccc(-c2cncc(C(=O)Nc3cccc(C)c3)n2)cc1 CHEMBL1277958 IC50 1.0 nM
NS(=O)(=O)c1cc(NC(=O)c2cc(CC3CC3)cnc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4745699 IC50 1.0 nM
COc1c(Cl)cc(Oc2ccc(OC(F)(F)F)c(F)c2OC)c(C(=O)Nc2ccnc(C(N)=O)c2)c1F CHEMBL4744908 IC50 1.3 nM
COc1c(Oc2cc(Cl)c(C)c(F)c2C(=O)Nc2ccnc(C(N)=O)c2)ccc(OC(F)(F)F)c1F CHEMBL4750365 IC50 1.4 nM
Cc1cc(C(=O)Nc2ccnc(S(N)(=O)=O)c2)c(N2CCCC(F)(F)CC2)nc1C CHEMBL4764433 IC50 1.6 nM
COc1c(Oc2cc(C(F)(F)F)c(OC)c(F)c2C(=O)Nc2ccnc(C(N)=O)c2)ccc(OC(F)(F)F)c1F CHEMBL4787299 IC50 1.6 nM
COc1cc(Oc2ccc(OC(F)(F)F)c(F)c2OC)c(C(=O)Nc2ccnc(C(N)=O)c2)c(F)c1Cl CHEMBL4756380 IC50 1.7 nM
COc1cc(OC(F)(F)F)ccc1Oc1cc(OC)c(C(F)(F)F)c(F)c1C(=O)Nc1ccnc(C(N)=O)c1 CHEMBL4782190 IC50 1.8 nM
Cc1ccccc1CNC(=O)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269882 IC50 2.0 nM
Cc1cc(C)cc(NC(=O)c2ccc(-c3ccc(OC(F)(F)F)cc3)o2)c1 CHEMBL1270797 IC50 2.0 nM
CCOc1ccc(-c2cncc(C(=O)Nc3cc(C)cc(C)c3)n2)cc1 CHEMBL1277877 IC50 2.0 nM
CCOc1ccc(-c2cncc(C(=O)NCc3ccccc3C)n2)cc1 CHEMBL1277959 IC50 2.0 nM
CCC[C@H](N)c1nc2cc(C(C)(C)C)ccc2[nH]1 CHEMBL4483603 IC50 2.0 nM
COc1cc(OC(F)(F)F)ccc1Oc1ccc(C(F)(F)F)c(Cl)c1C(=O)Nc1ccnc(C(N)=O)c1 CHEMBL4785523 IC50 2.0 nM
COc1cc(OC(F)(F)F)ccc1Oc1ccc(C(F)(F)F)c(Br)c1C(=O)Nc1ccnc(C(N)=O)c1 CHEMBL4761578 IC50 2.0 nM
COc1c(Oc2ccc(Cl)c(F)c2C(=O)Nc2ccnc(C(N)=O)c2)ccc(OC(F)(F)F)c1F CHEMBL4763419 IC50 2.3 nM
NS(=O)(=O)c1cc(NC(=O)c2cc(Cl)c(C3CCC3)nc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4743638 IC50 2.6 nM
NS(=O)(=O)c1cc(NC(=O)c2cc(OC(F)(F)F)cnc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4751356 IC50 2.8 nM
O=C(NCc1cccnc1OCC(F)(F)F)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270208 IC50 3.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(Cl)cc3)n2)c1 CHEMBL1277514 IC50 3.0 nM
NS(=O)(=O)c1cc(NC(=O)c2ccc(C3CC3)nc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4748189 IC50 3.0 nM
COc1c(Oc2ccc(C(F)(F)F)c(C)c2C(=O)Nc2ccnc(C(N)=O)c2)ccc(OC(F)(F)F)c1F CHEMBL4764805 IC50 3.0 nM
Cc1ccc(C(=O)Nc2ccnc(S(N)(=O)=O)c2)c(N2CCCC(F)(F)CC2)n1 CHEMBL4778738 IC50 3.1 nM
NS(=O)(=O)c1cc(NC(=O)c2cc(Cl)cnc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4777784 IC50 3.9 nM
O=C(NCc1ccccc1Cl)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269883 IC50 4.0 nM
COc1cc(OC(F)(F)F)ccc1Oc1ccc(C(F)(F)F)c(C)c1C(=O)Nc1ccnc(C(N)=O)c1 CHEMBL4759624 IC50 4.0 nM
NS(=O)(=O)c1cc(NC(=O)c2cc(C(F)(F)F)cnc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4796719 IC50 4.1 nM
NS(=O)(=O)c1cc(NC(=O)c2cc(Cl)c(C3CC3)nc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4759995 IC50 4.5 nM
Cc1cccc(NC(=O)c2cncc(-c3ccc(OC(F)(F)F)cc3)n2)c1 CHEMBL1278223 IC50 5.0 nM
NS(=O)(=O)c1cc(NC(=O)c2ccc(C(F)(F)F)nc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4788313 IC50 5.3 nM
NS(=O)(=O)c1cc(NC(=O)c2ccc(Cl)nc2N2CCCC(F)(F)CC2)ccn1 CHEMBL4752525 IC50 5.8 nM
COc1cc(NC(=O)c2cncc(-c3ccc(Cl)cc3)n2)cc(OC)c1 CHEMBL1277512 IC50 6.0 nM
Cc1cccc(NC(=O)c2cncc(-c3ccc(Cl)cc3)n2)c1 CHEMBL1277513 IC50 6.0 nM
Cc1nc(N2CCC(F)(F)CC2)c(C(=O)Nc2ccnc(S(N)(=O)=O)c2)cc1C1CCC1 CHEMBL4753100 IC50 6.5 nM
CCOc1ncccc1CNC(=O)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270207 IC50 7.0 nM
COc1cc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc(OC)c1 CHEMBL250699 IC50 8.0 nM
O=C(NCc1ccccc1N1CCCCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269990 IC50 8.0 nM
Cc1cc(C)cc(NC(=O)c2nsc(-c3ccc(OC(F)(F)F)cc3)n2)c1 CHEMBL1271105 IC50 8.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(C#N)cc3)n2)c1 CHEMBL1278044 IC50 8.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(Cl)cc3)c2)c1 CHEMBL1271416 IC50 9.0 nM
O=C(NCc1ccccc1N1CCOCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269991 IC50 10.0 nM
CO[C@H](C)[C@H](N)c1nc2cc(-c3ccc(C#N)c(F)c3)ccc2[nH]1 CHEMBL3617059 IC50 10.5 nM
Cc1nc(N2CCC(F)(F)CC2)c(C(=O)Nc2ccnc(S(N)(=O)=O)c2)cc1C#CC1CC1 CHEMBL4763229 IC50 12.0 nM
Cc1cc(OC(F)(F)F)ccc1N1CN(c2ccc(=O)[nH]c2C)C(=O)c2cc(C(F)(F)F)ncc21 CHEMBL5428332 pIC50 12.59 nM
O=C(NCc1cccnc1N1CCCCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270301 IC50 14.0 nM
C[C@@H](C(N)=O)[C@H](N)c1nc2ccc(C(C)(C)C)cc2[nH]1 CHEMBL4297317 IC50 15.0 nM
Cc1ccccc1CNC(=O)c1cncc(-c2ccc(OC(F)(F)F)cc2)n1 CHEMBL1278224 IC50 18.0 nM
CO[C@H](C)[C@H](N)c1nc2cc(-c3ccc(C#N)cc3F)ccc2[nH]1 CHEMBL4455868 IC50 18.0 nM
O=C(NCCc1ccc(Cl)cc1)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277607 IC50 19.0 nM
O=C(NCc1cccnc1N1CCOCC1)c1cncc(-c2ccc(OC(F)(F)F)cc2)n1 CHEMBL1276882 IC50 19.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(OC(F)(F)F)cc3)n2)c1 CHEMBL1271106 IC50 21.0 nM
O=C(NCc1ccccc1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1271417 IC50 22.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(C#N)cc3)c2)c1 CHEMBL1271309 IC50 23.0 nM
CO[C@H](C)[C@H](N)c1nc2cc(C(C)(C)C)ccc2[nH]1 CHEMBL4474590 IC50 24.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(OC(F)(F)F)cc3)c2)c1 CHEMBL1271206 IC50 26.0 nM
Cc1ccccc1CNC(=O)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277606 IC50 27.0 nM
CC(C)(C)c1ccc(-c2ccc(C(=O)N3CCN(C4CCCCC4)CC3)o2)cc1 CHEMBL486495 IC50 30.0 nM
O=C(NCc1cccnc1N1CCCC1)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277876 IC50 30.0 nM
CC(C)(C)c1ccc2[nH]c([C@H]3C[C@@H](O)CN3)nc2c1 CHEMBL4562194 IC50 31.0 nM
CCc1c(N2CN(c3ccc(=O)[nH]c3C)C(=O)c3cc(C(F)(F)F)ncc32)ccc(F)c1F CHEMBL5429977 pIC50 31.62 nM
Cc1cc(F)ccc1Oc1cc(C(F)(F)F)ccc1C(=O)Nc1ccn(COP(=O)(O)O)c(=O)c1 CHEMBL3906455 IC50 33.45 nM
N[C@H](COCc1ccccc1)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4091868 IC50 36.0 nM
O=C(NCc1cccnc1N1CCOCC1)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277700 IC50 37.0 nM
Cc1cc(OC(F)(F)F)ccc1N1CN(c2cc(F)c(=O)[nH]c2C)C(=O)c2cc(C(F)(F)F)ncc21 CHEMBL5401722 pIC50 39.81 nM
CC(C)c1ccc2[nH]c([C@@H](N)[C@@H](C)O)nc2c1 CHEMBL4457824 IC50 43.0 nM
CC(C)(C)c1ccc2[nH]c([C@H]3CCCN3)nc2c1 CHEMBL4564889 IC50 43.0 nM
C[C@@H](C(N)=O)[C@H](N)c1cn2cc(C(C)(C)C)ccc2n1 CHEMBL4452291 IC50 45.0 nM
NC1(Cc2nc(-c3ccc(OC(F)(F)F)cc3)c[nH]2)COC1 CHEMBL4096468 IC50 47.0 nM
CC(C)Oc1cccc(NC(=O)c2cncc(-c3ccc(C#N)cc3)n2)c1 CHEMBL1278045 IC50 49.0 nM
Cc1nc(N2CCCC(F)(F)CC2)c(C(=O)Nc2ccc3c(c2)C(=O)NC3)cc1Cl CHEMBL5410331 IC50 50.18 nM
Cc1cc(C)cc(NC(=O)c2csc(-c3ccc(OC(F)(F)F)cc3)n2)c1 CHEMBL1270999 IC50 51.0 nM
CC(C)(N)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4084106 IC50 53.0 nM
C[C@@H](O)[C@H](N)c1nc2cc(C(C)(C)C)ccc2[nH]1 CHEMBL4571436 IC50 59.0 nM
Cc1[nH]c(=O)ccc1N1CN(c2ccc(F)cc2C(C)C)c2cnc(C(F)(F)F)cc2C1=O CHEMBL5429034 pIC50 63.1 nM
Cc1[nH]c(=O)ccc1N1CN(c2ccc(F)c(F)c2C)c2cnc(C(F)(F)F)cc2C1=O CHEMBL5399954 pIC50 63.1 nM
Cc1cc(C)cc(NC(=O)c2cccc(-c3ccc(OC(F)(F)F)cc3)n2)c1 CHEMBL1271205 IC50 64.0 nM
CC(C)(C)c1ccc2[nH]c([C@@](C)(N)CO)nc2c1 CHEMBL4546247 IC50 65.0 nM
Cc1cccc(NC(=O)c2ccc(-c3ccc(C#N)cc3)o2)c1 CHEMBL401258 IC50 79.0 nM
CCc1cc(F)ccc1N1CN(c2ccc(=O)[nH]c2C)C(=O)c2cc(C(F)(F)F)ncc21 CHEMBL5417162 pIC50 79.43 nM
COC[C@@](C)(N)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4069225 IC50 84.0 nM
O=C(NCc1cccnc1N1CCOCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270302 IC50 87.0 nM
C[C@@H](O)[C@H](N)c1nc2cc(S(F)(F)(F)(F)F)ccc2[nH]1 CHEMBL4521566 IC50 95.0 nM
O=C(NCc1cccnc1Cl)c1cncc(-c2ccc(OC(F)(F)F)cc2)n1 CHEMBL1276881 IC50 99.0 nM
Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(F)cc3)c2)c1 CHEMBL1271415 IC50 100.0 nM
CC(C)(C)c1ccc2[nH]c([C@@H](N)CO)nc2c1 CHEMBL4468605 IC50 106.0 nM
C[C@@H]1CN(C(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)nc4)ccc3n2)CCN1 CHEMBL3932839 IC50 120.0 nM
CC(C)CC[C@H](N)c1nc2cc(C(C)(C)C)ccc2[nH]1 CHEMBL3341974 IC50 127.0 nM
CC(C)(C)c1ccc2[nH]c([C@H](N)CC(N)=O)nc2c1 CHEMBL4590816 IC50 130.0 nM
O=C(NCc1cccnc1Cl)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270100 IC50 140.0 nM
NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3cc(F)ccc3OCC(F)(F)C(F)(F)F)c2)n1 CHEMBL1631102 IC50 149.0 nM
Cc1ccccc1CNC(=O)c1cncc(-c2ccc(C#N)cc2)n1 CHEMBL1278138 IC50 150.0 nM
CC(=O)Nc1ccc(-c2cc(Cl)cc(Cl)c2Cl)c(N)n1 CHEMBL3589893 IC50 160.0 nM
CN(Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1)C(=O)[C@@H]1CCC[C@H]1C(=O)NCc1ccc(OC(F)(F)F)cc1 CHEMBL205412 Ki 180.0 nM
Cc1cc(C)cc(NC(=O)c2coc(-c3ccc(OC(F)(F)F)cc3)n2)c1 CHEMBL1270899 IC50 180.0 nM
NC1(Cc2nc(-c3ccc(OC(F)(F)F)cc3)c[nH]2)CCCOC1 CHEMBL3341975 IC50 190.0 nM
CNC(=O)c1ccc(-c2cc(Cl)cc(Cl)c2Cl)c(N)n1 CHEMBL3589894 IC50 190.0 nM
COc1ccc(Cl)c(-c2ccc(NC(=O)c3ccnn3C)nc2N)c1 CHEMBL3589904 IC50 190.0 nM
NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3cccc(OC(F)(F)F)c3OCC(F)(F)C(F)(F)F)c2)n1 CHEMBL1631103 IC50 203.0 nM
O=C1C[C@@H](NC(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)cn4)ccc3n2)CCN1 CHEMBL3955151 IC50 213.0 nM
CC(C)[C@@H](O)[C@H](N)c1nc2cc(C(C)(C)C)ccc2[nH]1 CHEMBL4583673 IC50 227.0 nM
O=C(N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1)c1ccccc1OC(F)(F)F CHEMBL253659 IC50 230.0 nM
CC(C)(CN)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4089820 IC50 230.0 nM
Cc1nocc1C(=O)Nc1ccc(-c2ccccc2OC(F)(F)F)c(N)n1 CHEMBL2324355 IC50 260.0 nM
C[C@H](N)Cc1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4081959 IC50 260.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1 CHEMBL254497 IC50 270.0 nM
O=C(c1ccc(-c2ccc(Cl)cc2)o1)N1CCNCC1 CHEMBL521211 IC50 280.0 nM
Cc1cc(C)cc(NC(=O)c2cnc(-c3ccc(OC(F)(F)F)cc3)o2)c1 CHEMBL1270898 IC50 280.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1cc(F)ccc1Cl)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL252837 IC50 295.0 nM
NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3cccc(C(F)(F)F)c3OCC(F)(F)C(F)(F)F)c2)n1 CHEMBL1631104 IC50 299.0 nM
O=C(c1ccc(-c2ccc(Cl)cc2)o1)N1CCN(C2CCCCC2)CC1 CHEMBL482676 IC50 300.0 nM
O=C(NCc1ccncc1N1CCOCC1)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277792 IC50 320.0 nM
C[C@@H](N)Cc1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4099963 IC50 320.0 nM
O=C(c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1)N1CCN(C2CCC2)CC1 CHEMBL3924612 IC50 334.0 nM
N[C@@H](COCc1ccccc1)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4062394 IC50 340.0 nM
CC(C)(C)CC(=O)N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1 CHEMBL252038 IC50 361.0 nM
O=C(N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1)c1ccccc1C(F)(F)F CHEMBL400260 IC50 366.0 nM
O=C(c1ccc2cc(Oc3ccc(OC(F)(F)F)cn3)ccc2n1)N1CCNCC1 CHEMBL3924034 IC50 382.0 nM
CC(C)C[C@@H](N)Cc1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4061739 IC50 390.0 nM
Cc1nocc1C(=O)Nc1cnc(-c2cc(Cl)cc(Cl)c2Cl)c(N)n1 CHEMBL3617058 IC50 417.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1c(F)ccc(F)c1F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL252836 IC50 446.0 nM
O=C(NCc1nc2cccnc2n1C1(c2ccccc2)CC1)[C@@H](Cc1c(F)ccc(F)c1F)NC(=O)C1(C(F)(F)F)CC1 CHEMBL403809 IC50 446.0 nM
CCN1CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)cn4)ccc3n2)CC1=O CHEMBL3909018 IC50 468.0 nM
Cc1cc(C)cc(NC(=O)c2nc(-c3ccc(OC(F)(F)F)cc3)no2)c1 CHEMBL1270998 IC50 470.0 nM
O=C(Nc1cc[nH]c(=O)c1)c1ccc(C(F)(F)F)cc1N1CCC(C(F)(F)F)CC1 CHEMBL5413130 IC50 471.81 nM
COC[C@@H]1CN(C(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)nc4)ccc3n2)CCN1 CHEMBL3904532 IC50 491.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1Cl)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL404621 IC50 500.0 nM
COc1ccc(Cl)c(-c2ccc(NC(=O)c3conc3C)nc2N)c1 CHEMBL3589903 IC50 500.0 nM
CCN1CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)F)cn4)ccc3n2)CC1=O CHEMBL3952300 IC50 501.0 nM
C#CC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@@H]3CSSC[C@@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(N)=O)[C@@H](C)CC)NC(=O)[C@H](Cc4c[nH]c5ccc(Br)cc45)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC(=O)[C@H](CCCC)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC1=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N3)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC2=O CHEMBL4169884 IC50 509.0 nM
C[C@@H](O)[C@H](N)c1nc2cc(C(F)(F)F)ccc2[nH]1 CHEMBL4447338 IC50 534.0 nM
NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3ccccc3OC(F)(F)F)c2)n1 CHEMBL1631088 IC50 554.0 nM
C[C@H](O)[C@@H](N)c1nc2cc(-c3ccc(C#N)cc3)ccc2[nH]1 CHEMBL4453894 IC50 579.0 nM
CC1(c2ccc3[nH]c([C@@H](N)CO)nc3c2)CC1 CHEMBL4443309 IC50 593.0 nM
CC(C)(C)c1ccc2[nH]c(C(C)(C)N)nc2c1 CHEMBL4466809 IC50 607.0 nM
FC(F)(F)Oc1ccc(-c2c[nH]c(C3CCCNC3)n2)cc1 CHEMBL4092210 IC50 620.0 nM
O=C(NC1CCS(=O)(=O)C1)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 CHEMBL3929628 IC50 648.0 nM
Cc1nocc1C(=O)Nc1ccc(-c2cc(Cl)cc(Cl)c2Cl)c(N)n1 CHEMBL3589901 IC50 670.0 nM
O=C(NCC(F)(F)F)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 CHEMBL3896768 IC50 670.0 nM
CC(C)(C)C(=O)ON[C@H](Cc1ccccc1)C(=O)N[C@@H]1CCc2ccccc2N(CC(F)(F)F)C1=O CHEMBL2324352 IC50 680.0 nM
CC(C)C[C@@H](N)Cc1nc(-c2ccc(Cl)cc2)c[nH]1 CHEMBL4105252 IC50 680.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1c(F)cccc1F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL400642 IC50 685.0 nM
N[C@@H]1[C@H]2CN(C(=O)c3ccc4cc(Oc5ccc(C(F)F)cn5)ccc4n3)C[C@@H]12 CHEMBL3915627 IC50 702.0 nM
CCC(C)c1ccc2[nH]c([C@@H](N)CO)nc2c1 CHEMBL4534370 IC50 708.0 nM
CC(C)(N)c1nc(-c2ccc(Cl)cc2)c[nH]1 CHEMBL4104203 IC50 710.0 nM
C[C@@H](O)[C@H](N)c1nc2cc(C(C)(C)C#N)ccc2[nH]1 CHEMBL4458495 IC50 728.0 nM
CN(C)C(=O)CNC(=O)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 CHEMBL3970942 IC50 740.0 nM
CN[C@@H](CC(N)=O)c1nc2cc(C(C)(C)C)ccc2[nH]1 CHEMBL4557777 IC50 742.0 nM
Cn1nccc1C(=O)Nc1ccc(-c2cc(Cl)cc(Cl)c2Cl)c(N)n1 CHEMBL3589900 IC50 750.0 nM
CC1(NC(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)cn4)ccc3n2)COC1 CHEMBL3946981 IC50 774.0 nM
Cc1cc(C)cc(NC(=O)c2ccnc(-c3ccc(OC(F)(F)F)cc3)c2)c1 CHEMBL1271308 IC50 780.0 nM
C[C@](N)(CF)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 CHEMBL4104889 IC50 790.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL254918 IC50 793.0 nM
CC(C)(C)c1ccc2[nH]c([C@@H](N)C(C)(C)C(N)=O)nc2c1 CHEMBL4456468 IC50 797.0 nM
NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3c(F)cccc3OC(F)(F)F)c2)n1 CHEMBL1631098 IC50 802.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1cccc(F)c1C(F)(F)F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL252240 IC50 806.0 nM
O=C(c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1)N1CC(N2CC[C@@H](F)C2)C1 CHEMBL3958587 IC50 821.0 nM
O=C(N[C@H](Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1)c1ccccc1OC(F)(F)F CHEMBL400262 IC50 825.0 nM
O=C(c1ccc2cc(Oc3ccc(OC(F)F)cn3)ccc2n1)N1CCNCC1 CHEMBL3961516 IC50 870.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL252437 IC50 880.0 nM
NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3ccccc3C(F)(F)F)c2)n1 CHEMBL1631093 IC50 915.0 nM
Cn1nccc1C(=O)Nc1ccc(-c2cc(Cl)ccc2Cl)c(N)n1 CHEMBL3589902 IC50 920.0 nM
O=C(NCC(=O)N1CCCC1)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 CHEMBL3933392 IC50 937.0 nM
CC(C)(C)OC(=O)N[C@H](Cc1ccccc1OC(F)(F)F)C(=O)NCc1nc2cccnc2n1C1(c2ccccc2)CC1 CHEMBL253660 IC50 985.0 nM
CO[C@H](C)[C@H](N)c1nc2cc(-c3ccc(C#N)nc3)ccc2[nH]1 CHEMBL4531177 IC50 998.0 nM
C[C@@H](NC(=O)c1ccc(-c2ccc(Cl)cc2)o1)C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)cc2)CC1 CHEMBL251241 IC50 1000.0 nM
COc1ccc(-c2c[nH]c(C(C)(C)N)n2)cc1 CHEMBL4095544 IC50 1000.0 nM