N=C1N[C@@]23[C@H]([C@H]4NC(=N)N2C[C@](OS(=O)(=O)O)(C[C@H]2[C@@H](CO)CON2C4=O)C3(O)O)N1COC(=O)NO CHEMBL3617050 IC50 0.0061 nM
Nc1nc2cc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)ccc2[nH]1 CHEMBL3617063 IC50 0.2 nM
CCCCCCCCCC[C@@H]1C[C@]2(CCCO2)NC(=N)N1 CHEMBL4060338 IC50 0.28 nM
N=C1N[C@H]2[C@H](COC(N)=O)NC(=N)N3CCC(O)(O)[C@]23N1 CHEMBL501134 IC50 1.0 nM
CCCCCCCCCC[C@H]1C[C@@]2(CCCO2)NC(=N)N1 CHEMBL4070670 IC50 2.0 nM
CC1(COc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CCC2(CC1)CC2 CHEMBL3662190 IC50 2.0 nM
N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(-c2cccc(C(F)(F)F)c2)cc1-c1ccnc(CNCCC2CCNCC2)c1 CHEMBL4217988 IC50 2.519 nM
Nc1noc2ccc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)cc12 CHEMBL3341983 IC50 4.2 nM
CCCCCCCCCC[C@H]1NC(=N)N[C@@]2(CCCO2)[C@H]1C(=O)O CHEMBL4064160 EC50 5.3 nM
CC1(COc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CCC(F)(F)CC1 CHEMBL3662077 IC50 6.0 nM
O=S(=O)(Nc1nnc2cc(OCC34CC5CC(CC(C5)C3)C4)c(C3CC3)cn12)C1CC1 CHEMBL4290579 IC50 7.0 nM
CCCCCCCCCC[C@@H]1NC(=N)N[C@]2(CCCO2)[C@@H]1C(=O)O CHEMBL4082248 IC50 7.5 nM
CS(=O)(=O)Nc1nnc2cc(COc3cc(Cl)cc(Cl)c3)c(C3CC3)cn12 CHEMBL4285790 IC50 10.0 nM
O=S(=O)(Nc1ccncn1)c1cc2c(cc1F)[C@@H](N1CC[C@H](C(F)(F)F)C[C@@H]1c1ccccn1)CCO2 CHEMBL4464990 Kd 12.0 nM
O=S(=O)(Nc1cccc(F)n1)c1cc(F)c(O[C@H]2CCN(CC(F)(F)F)C[C@@H]2c2ccc(F)c(F)c2)c(F)c1 CHEMBL4854735 IC50 12.0 nM
CS(=O)(=O)Nc1nnc2cc(OCC34CC5CC(CC(C5)C3)C4)c(C3CC3)cn12 CHEMBL4279238 IC50 14.0 nM
NC1=N[C@H](O)[C@H]2[C@H]3O[C@]4(O)O[C@@H]([C@@H](O)[C@@]2(N1)[C@@H]4O)[C@]3(O)CO CHEMBL507974 IC50 14.0 nM
O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F CHEMBL3657855 IC50 18.9 nM
C[C@H](c1cccc2c1CNCC2)n1c(=O)oc2cc(S(=O)(=O)Nc3ncns3)ccc21 CHEMBL4068937 IC50 29.0 nM
C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1 CHEMBL5094715 IC50 38.0 nM
CSCC[C@@H]1NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]3CSSC[C@H](NC(=O)[C@H](C(C)C)NC1=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)O)CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC3=O)C(=O)N2 CHEMBL4224739 IC50 41.0 nM
O=C(NCc1ccccc1N1CCCCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269990 IC50 50.0 nM
CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3cc(C(F)(F)F)ccc3Cl)CC2)cc1F CHEMBL4444707 Kd 64.0 nM
O=C(NCc1cccnc1N1CCCCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270301 IC50 70.0 nM
CSCC[C@@H]1NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]3CSSC[C@H](NC(=O)[C@H](C(C)C)NC1=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c4ccccc14)C(=O)O)CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC3=O)C(=O)N2 CHEMBL3318132 IC50 79.0 nM
CC(C)(C)c1ccc(-c2ccc(C(=O)N3CCN(C4CCCCC4)CC3)o2)cc1 CHEMBL486495 IC50 100.0 nM
Cc1ccccc1CNC(=O)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269882 IC50 110.0 nM
Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl CHEMBL2325014 IC50 110.0 nM
O=C(NCc1ccccc1N1CCOCC1)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1269991 IC50 120.0 nM
CSCC[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)CSSC[C@@H]2NC(=O)[C@@H]3CSSC[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@H](C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O)NC(=O)[C@H](Cc4ccc(O)cc4)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](Cc4ccccc4)NC1=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N3)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCCN)NC2=O CHEMBL4588728 IC50 120.0 nM
Cc1nn([C@@H]2CCN([C@H](C)c3cc(Cl)cc(Cl)c3)C2)c2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc12 CHEMBL4471012 Kd 140.0 nM
Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1F CHEMBL2324411 IC50 149.0 nM
FC(F)(F)c1cccc(-c2c[nH]c(-c3cccc(C(F)(F)F)c3)n2)c1 CHEMBL510722 IC50 200.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)C(c1ccccc1)c1ccccc1 CHEMBL3617053 IC50 240.0 nM
Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1C#N CHEMBL2324753 IC50 276.0 nM
O=C(c1ccc(-c2ccc(Cl)cc2)o1)N1CCN(C2CCCCC2)CC1 CHEMBL482676 IC50 350.0 nM
CCOc1ccc(-c2cncc(C(=O)Nc3cc(C)cc(C)c3)n2)cc1 CHEMBL1277877 IC50 360.0 nM
O=S(=O)(Nc1nncs1)c1cc(Cl)c(Oc2ccc(C(F)(F)F)cc2-c2ccnnc2)cc1F CHEMBL2324776 IC50 398.0 nM
FC(F)(F)Oc1ccc(-c2ccc3nnc(C(F)(F)F)n3c2)cc1 CHEMBL3809595 IC50 400.0 nM
O=C(NCc1ccc(OC(F)(F)F)c(Cl)c1)c1ccc(S(=O)(=O)Nc2nccs2)c(F)c1 CHEMBL4276884 IC50 429.0 nM
CCOc1ccc(-c2cncc(C(=O)NCc3ccccc3C)n2)cc1 CHEMBL1277959 IC50 470.0 nM
CCCCNc1ccc(C(=O)OCCN(C)C)cc1 CHEMBL698 IC50 490.0 nM
O=C1N(Cc2ccc(C(F)(F)F)o2)c2ccccc2[C@]12COc1cc3c(cc12)OCO3 CHEMBL3707218 IC50 600.0 nM
CCCCOc1ccc(C(=O)NC(=N)NCCCCc2ccccc2)cc1 CHEMBL108347 IC50 630.0 nM
CCOc1ncccc1CNC(=O)c1cncc(-c2ccc(Cl)cc2)c1 CHEMBL1270207 IC50 670.0 nM
CCOc1ccc(C(=O)NC(=N)NCCCCc2ccccc2)cc1 CHEMBL108727 IC50 760.0 nM
COc1ccc(C(=O)NC(=N)NCCCCc2ccccc2)cc1 CHEMBL321883 IC50 820.0 nM
N=C(NCCCCc1ccccc1)NC(=O)c1cccc2ccccc12 CHEMBL110572 IC50 860.0 nM
O=C(NCc1ccc(OC(F)(F)F)c(Cl)c1)c1ccc(S(=O)(=O)Nc2ncns2)c(F)c1 CHEMBL4293085 IC50 920.0 nM
O=C(NCCc1ccc(Cl)cc1)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277607 IC50 1000.0 nM
O=C(NCc1cccnc1N1CCCC1)c1cncc(-c2ccc(Cl)cc2)n1 CHEMBL1277876 IC50 1000.0 nM
CCOc1ccc(-c2cncc(C(=O)Nc3cccc(C)c3)n2)cc1 CHEMBL1277958 IC50 1000.0 nM
Cc1ccccc1CNC(=O)c1cncc(-c2ccc(C#N)cc2)n1 CHEMBL1278138 IC50 1000.0 nM