Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)cnc12 CHEMBL3092468 IC50 1.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(C(F)(F)F)ccc4F)cc3)ccc12 CHEMBL3356029 IC50 1.0 nM
O=C(NC1CCN(CCO)C1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5093306 IC50 1.0 nM
O=C(NC1CCN(CC2CC2)C1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5087657 IC50 1.0 nM
NC(=O)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5075992 IC50 1.0 nM
O=C(NCc1ncn[nH]1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5075362 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCC3(CN)COC3)c12 CHEMBL5074684 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCC(CO)CO)c12 CHEMBL5088069 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCC3CN(C(C)C)C3)c12 CHEMBL5087162 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCCNC3)c12 CHEMBL5081869 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCNCC3)c12 CHEMBL5083625 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCNCC3(F)F)c12 CHEMBL5085476 IC50 1.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCNCC3F)c12 CHEMBL5070612 IC50 1.0 nM
COc1nc(-c2ccc(NS(=O)(=O)c3cc(C)ccc3F)cc2)nc2[nH]ncc12 CHEMBL3355031 IC50 1.5 nM
COc1ccc(Cl)c(S(=O)(=O)Nc2ccc(-c3cnc4c(C)n[nH]c4n3)cc2)c1 CHEMBL3092467 IC50 2.0 nM
Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3cnc4c(C)n[nH]c4n3)cc2)c1 CHEMBL3092466 IC50 2.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4Cl)c(F)c3)cnc12 CHEMBL3092463 IC50 2.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)c(F)c3)cnc12 CHEMBL3092462 IC50 2.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)ccc12 CHEMBL3356024 IC50 2.0 nM
COc1ccc(Cl)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1 CHEMBL3356044 IC50 2.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)c(F)cc4F)cc3)cnc12 CHEMBL3356048 IC50 2.0 nM
Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1 CHEMBL3356049 IC50 2.0 nM
COc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1 CHEMBL3356050 IC50 2.0 nM
COc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1 CHEMBL3356053 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4Cl)cc3)cnc12 CHEMBL3356059 IC50 2.0 nM
O=C(c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12)N1CCNCC1 CHEMBL5071460 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCCCO)c12 CHEMBL5093411 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(Oc3ccc(O)nc3)c12 CHEMBL5083859 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCC3CNCCO3)c12 CHEMBL5071544 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CC(C)(C)N(C)C(C)(C)C3)c12 CHEMBL5081330 IC50 2.0 nM
CCN1CCC(Oc2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc3[nH]nc(C)c23)CC1 CHEMBL5077848 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCN(C(C)C)CC3)c12 CHEMBL5094921 IC50 2.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCN(C4CC4)CC3)c12 CHEMBL5093302 IC50 2.0 nM
Cc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3cnc4c(C)n[nH]c4n3)cc2)c1 CHEMBL3092465 IC50 3.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)cnc12 CHEMBL3092460 IC50 3.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4ccc(Br)s4)cc3)ccc12 CHEMBL3356018 IC50 3.0 nM
Cc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1 CHEMBL3356052 IC50 3.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)c(F)c3)cnc12 CHEMBL3356054 IC50 3.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4C#N)cc3)cnc12 CHEMBL3356060 IC50 3.0 nM
O=C(NCCn1cnnc1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5086767 IC50 3.0 nM
N#Cc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(-c2ncc3c(N)n[nH]c3n2)cc1 CHEMBL5082336 IC50 3.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCC(F)(F)CN)c12 CHEMBL5086320 IC50 3.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CC(C)(C)NC(C)(C)C3)c12 CHEMBL5077971 IC50 3.0 nM
COCCN1CCC(Oc2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc3[nH]nc(C)c23)CC1 CHEMBL5083614 IC50 3.0 nM
O=S(=O)(Nc1ccc(-c2nc(O[C@H]3CC[C@H](O)CC3)c3cn[nH]c3n2)cc1)c1cc(Cl)ccc1F CHEMBL3355029 IC50 3.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)cnc12 CHEMBL3092464 IC50 4.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)sc4Cl)cc3)cnc12 CHEMBL3356039 IC50 4.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(Br)ccc4Cl)cc3)ccc12 CHEMBL3356034 IC50 4.0 nM
CC(C)N1CC[C@H](NC(=O)c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)nc3[nH]ncc23)C1 CHEMBL5074701 IC50 4.0 nM
CNC(=O)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5078693 IC50 4.0 nM
O=C(NCc1nn[nH]n1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5094428 IC50 4.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(Oc3ccc(N)nc3)c12 CHEMBL5081823 IC50 4.0 nM
CC(C)Cc1cc(-c2c[nH]c3ncc(-c4ccccc4)cc23)ccc1C(=O)O CHEMBL564555 IC50 5.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4Cl)cc3)cnc12 CHEMBL3092461 IC50 5.0 nM
O=C(NCc1cccc(O)c1)Nc1nc(-c2ccncc2)cs1 CHEMBL3218297 IC50 5.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCOCC3)c12 CHEMBL5085315 IC50 5.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCC(=O)CC3)c12 CHEMBL5083477 IC50 5.0 nM
N#Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc(-c2ccc3c(N)n[nH]c3c2)cc1 CHEMBL3356026 IC50 6.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(Br)ccc4F)cc3)ccc12 CHEMBL3356035 IC50 6.0 nM
O=C(NC1CCN(C2CC2)C1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5079781 IC50 6.0 nM
CCNC(=O)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5078340 IC50 6.0 nM
CCN1CCCC(Oc2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc3[nH]nc(C)c23)C1 CHEMBL5082604 IC50 6.0 nM
Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(OCC4CNCCO4)c4cn[nH]c4n3)cc2)c1 CHEMBL3355033 IC50 6.2 nM
Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(C4CC4)c4cn[nH]c4n3)cc2)c1 CHEMBL3355032 IC50 6.5 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 6.75 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)ccc12 CHEMBL3356037 IC50 7.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cccc(F)c4F)cc3)ccc12 CHEMBL3356031 IC50 9.0 nM
N#Cc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(-c2cnc3c(N)n[nH]c3n2)cc1 CHEMBL3356051 IC50 10.0 nM
O=C(NCCc1cc[nH]n1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5083393 IC50 10.0 nM
O=C(O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1C1CCCC1 CHEMBL558642 IC50 13.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)cnc12 CHEMBL3356058 IC50 13.0 nM
Cn1cc(S(=O)(=O)Nc2ccc(-c3ccc4c(N)n[nH]c4c3)cc2)c(C(F)(F)F)n1 CHEMBL3356019 IC50 14.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4ccccc4Cl)cc3)cnc12 CHEMBL3356041 IC50 14.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4Cl)cc3)ccc12 CHEMBL3356025 IC50 14.0 nM
CN1CCC(CNC(=O)c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)nc3[nH]ncc23)C1 CHEMBL5071556 IC50 14.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3)cnc12 CHEMBL3356047 IC50 15.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OCCC(=O)N(C)C)c12 CHEMBL5075203 IC50 15.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc5ccccc45)cc3)cnc12 CHEMBL3356038 IC50 16.0 nM
N#Cc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(-c2ccc3c(N)n[nH]c3c2)cc1 CHEMBL3356028 IC50 17.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4ccc(F)cc4Cl)cc3)cnc12 CHEMBL3978702 IC50 18.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)ncc12 CHEMBL3355036 IC50 19.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4ccco4)cc3)ccc12 CHEMBL3356020 IC50 19.0 nM
Nc1nc(CNC(=O)c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)nc3[nH]ncc23)cs1 CHEMBL5093744 IC50 19.0 nM
CCc1cc(-c2c[nH]c3ncc(-c4ccccc4)cc23)ccc1C(=O)O CHEMBL550110 IC50 20.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(F)c4Cl)cc3)cnc12 CHEMBL3356042 IC50 21.0 nM
CN1CCC(NC(=O)c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)nc3[nH]ncc23)C1 CHEMBL5084696 IC50 21.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4ccccc4F)cc3)cnc12 CHEMBL3356046 IC50 22.0 nM
CCOc1nc(-c2ccc(NS(=O)(=O)c3cc(Cl)ccc3F)cc2)nc2[nH]nc(C)c12 CHEMBL5090299 IC50 23.0 nM
CN(CCO)C(=O)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5080922 IC50 24.0 nM
O=C(NCC(F)(F)F)c1cc(-c2cnn3cc(-c4ccc(OCCN5CCCCC5)cc4)cnc23)cs1 CHEMBL4569508 IC50 27.0 nM
C=S(=O)(O)c1ccc2c(c1)C(C)(C)C1=[N+]2CCC2OC3CCN4C(=C3C=C12)C(C)(C)c1cc(CC(=O)NCCCC[C@@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)CCCCCNC(=O)[C@@H](CCCNC(=N)N)NC(=O)CCCCCCCNCCNS(=O)(=O)c2cccc3cnccc23)C(N)=O)ccc14 CHEMBL2023841 Kd 28.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)Cc4cc(F)ccc4F)cc3)ccc12 CHEMBL3356016 IC50 28.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3)cnc12 CHEMBL3356061 IC50 29.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(F)cc(F)c4Cl)cc3)cnc12 CHEMBL3911826 IC50 31.0 nM
O=C(O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1 CHEMBL550795 IC50 40.0 nM
CC(C)(C(=O)O)c1ccc(-c2c[nH]c3ncc(-c4cccc(C#N)c4)cc23)cc1 CHEMBL562931 IC50 40.0 nM
Cc1ccc(C#N)cc1S(=O)(=O)Nc1ccc(-c2ccc3c(N)n[nH]c3c2)cc1 CHEMBL3356027 IC50 46.0 nM
N#Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1 CHEMBL3896952 IC50 47.0 nM
CC(C)(C(=O)O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1 CHEMBL541759 IC50 50.0 nM
COc1ccc(Cl)c(S(=O)(=O)Nc2ccc(-c3ccc4c(N)n[nH]c4c3)cc2)c1 CHEMBL3356033 IC50 51.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)nc(OC3CCN(CC(F)(F)F)CC3)c12 CHEMBL5079143 IC50 55.0 nM
Cn1ncc(Cl)c1-c1cc(C(=O)N[C@@H]2CNCC[C@H]2c2ccc(F)c(F)c2)oc1Cl CHEMBL4457064 IC50 59.0 nM
COc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3nc(C4CC4)c4c(N)n[nH]c4n3)cc2)c1 CHEMBL3355035 IC50 61.0 nM
O=C(O)Cc1ccc(-c2c[nH]c3ncc(-c4ccc5ccccc5c4)cc23)cc1 CHEMBL549906 IC50 63.0 nM
CC(C)(C(=O)O)c1ccc(-c2c[nH]c3ncc(-c4ccc5ccccc5c4)cc23)cc1 CHEMBL561526 IC50 63.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(Cl)sc4Cl)cc3)ccc12 CHEMBL3356021 IC50 63.0 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)NCC(F)(F)F)c4)cnn3c2)cn1 CHEMBL4550702 IC50 63.0 nM
CC(C)NC(=O)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5084905 IC50 68.0 nM
Cn1ncc(Cl)c1-c1cc(C(=O)N[C@@H]2CN[C@H](CCO)C[C@H]2c2ccc(F)c(F)c2)oc1Cl CHEMBL4441825 IC50 102.0 nM
O=C(NCc1nncs1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5087068 IC50 109.0 nM
CCN1CCC(CNC(=O)c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)nc3[nH]ncc23)C1 CHEMBL5090286 IC50 109.0 nM
N#Cc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(-c2nc(OC3CCC(O)CC3)c3cn[nH]c3n2)cc1 CHEMBL3355027 IC50 110.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4ccccc4)cc3)ccc12 CHEMBL3356022 IC50 124.0 nM
CC(C(=O)O)c1ccc(-c2c[nH]c3ncc(-c4ccc5ccccc5c4)cc23)cc1 CHEMBL557108 IC50 125.0 nM
O=C(NCc1ncc[nH]1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5079183 IC50 128.0 nM
CC(C)COc1nc(-c2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc2)nc2[nH]nc(N)c12 CHEMBL3355034 IC50 130.0 nM
COc1cc(O)ccc1/C=N/NC(=O)Cc1cccc(O)c1 CHEMBL3356011 IC50 138.0 nM
CNC(=O)C[C@@H]1C[C@@H](c2ccc(F)c(F)c2)[C@H](NC(=O)c2cc(-c3c(Cl)cnn3C)c(Cl)o2)CN1 CHEMBL4440965 IC50 145.0 nM
c1ccc(-c2cnc3[nH]cc(-c4ccc(-c5nnn[nH]5)cc4)c3c2)cc1 CHEMBL564697 IC50 160.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4F)cc3)ccc12 CHEMBL3356036 IC50 169.0 nM
COc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(O[C@H]4CC[C@H](O)CC4)c4c(C)n[nH]c4n3)cc2)c1 CHEMBL3355030 IC50 170.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3)ccc12 CHEMBL3356032 IC50 186.0 nM
NNc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(-c2cnc3c(N)n[nH]c3n2)cc1 CHEMBL3356040 IC50 196.0 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 CHEMBL4568087 IC50 200.0 nM
CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5ccc6[nH]ccc6c5)c4c3)cc2)CC1 CHEMBL2436978 IC50 201.0 nM
Cn1ncc(Cl)c1-c1cc(C(=O)N[C@H](CN)Cc2ccc(F)c(F)c2)oc1Cl CHEMBL3137336 IC50 211.0 nM
CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(c3c2)-c2cn(nc2C(F)(F)F)CCCC1=O CHEMBL5093741 IC50 212.0 nM
Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(OC[C@H]4CN(CCCCCCOCCOCCOCC(=O)N[C@H](C(=O)N5C[C@H](O)C[C@H]5C(=O)NCc5ccc(-c6scnc6C)cc5)C(C)(C)C)CCO4)c4cn[nH]c4n3)cc2)c1 CHEMBL4795354 IC50 220.0 nM
CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O CHEMBL2205426 Ki 260.0 nM
C[C@@H](NC(=O)Nc1cc2[nH]ncc2c(CO)n1)c1ccccc1 CHEMBL4538174 IC50 270.0 nM
NCCCOc1nc(-c2ccc(NS(=O)(=O)c3cc(Cl)ccc3Cl)cc2)nc2[nH]ncc12 CHEMBL3355028 IC50 280.0 nM
CC(C)NCc1ccc(Nc2cc(-c3ccc(-c4ccc(O)cc4O)cc3)[nH]n2)cc1 CHEMBL398606 IC50 290.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)Cc4ccccc4)cc3)ccc12 CHEMBL3356015 IC50 315.0 nM
O=C(NCc1cocn1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5081215 IC50 327.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 331.0 nM
O=C1Nc2ccccc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL216543 IC50 380.0 nM
Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4ccccc4Cl)cc3)ccc12 CHEMBL3356023 IC50 396.0 nM
NCc1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1 CHEMBL554730 IC50 400.0 nM
Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4ccc(C(F)(F)F)cc4Cl)cc3)cnc12 CHEMBL3356045 IC50 407.0 nM
O=S(=O)(Nc1ccc(-c2cnc3c(NS(=O)(=O)c4cc(Cl)c(F)cc4F)n[nH]c3n2)cc1)c1cc(Cl)c(F)cc1F CHEMBL3909544 IC50 413.0 nM
O=S(=O)(Nc1ccc(-c2cnc3cn[nH]c3n2)cc1F)c1cccc(Cl)c1Cl CHEMBL3356057 IC50 419.0 nM
O=S(=O)(Nc1ccc(-c2cnc3cn[nH]c3n2)cc1)c1cc(Cl)ccc1Cl CHEMBL3356055 IC50 439.0 nM
O=S(=O)(Nc1ccc(-c2cnc3cn[nH]c3n2)cc1F)c1cc(Cl)ccc1Cl CHEMBL3356056 IC50 496.0 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 566.0 nM
OCCNc1nc(NCCc2ccccc2)c2cnn(/C=C/c3ccccc3)c2n1 CHEMBL4638374 Ki 600.0 nM
CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3cc[nH]c3n2)cc1 CHEMBL2006765 IC50 606.0 nM
CN(C)CCCNC(=O)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5083285 IC50 633.0 nM
O=S(=O)(Nc1ccc(-c2nc(OC3CCC(O)CC3)c3cn[nH]c3n2)cc1)c1cc(Cl)ccc1F CHEMBL3355026 IC50 670.0 nM
NCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL590109 IC50 690.0 nM
CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(c3c2)-c2cn(nc2C(F)(F)F)CCCC1=O CHEMBL5086263 IC50 690.0 nM
Cc1sc(C(=O)N[C@@H]2[C@H](N)CCCC2(F)F)cc1-c1cnn2cc(Cl)cnc12 CHEMBL4552628 IC50 810.0 nM
Cc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4Cl)cc3)ncc12 CHEMBL3355025 IC50 830.0 nM
O=C(NCc1cc[nH]n1)c1cc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc2[nH]ncc12 CHEMBL5093575 IC50 963.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM