CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC2CCN(C(=O)OC3(C)CC3)CC2)c2ccccc2n(C)c1=O CHEMBL4172856 IC50 6.5 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCc2ccnc(-c3ccccc3)c2)c2ccccc2n(C)c1=O CHEMBL4177314 IC50 16.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc2n(C)c1=O CHEMBL4646354 IC50 30.0 nM
COc1cc(CN(C)C(=O)c2c(OCCCC3CCN(C(=O)OC4(C)CC4)CC3)c3cccnc3n(C)c2=O)cc(C(F)(F)F)c1 CHEMBL4645607 IC50 45.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC2CCN(C(=O)OC3(C)CC3)CC2)c2cccnc2n(C)c1=O CHEMBL4641888 IC50 47.0 nM
Clc1cccc(Cl)c1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4203399 IC50 90.0 nM
CCc1ccccc1COc1ccccc1C(=O)Nc1cccnc1 CHEMBL4540510 IC50 91.0 nM
COc1cc(CN(C)C(=O)c2c(OCCCC3CCN(C(=O)OC(C)(C)C)CC3)c3ccccc3n(C)c2=O)cc(OC)c1 CHEMBL4638337 IC50 91.0 nM
Fc1ccc(Cl)c(COc2cccc3onc(Nc4cccnc4)c23)c1 CHEMBL4204352 IC50 100.0 nM
Clc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 CHEMBL4214637 IC50 100.0 nM
FC(F)(F)Oc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4207944 IC50 110.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC(F)(F)F)c2ccccc2n(C)c1=O CHEMBL4634669 IC50 120.0 nM
COc1cc(CN(C)C(=O)c2c(OCCCC3CCN(C(=O)OC(C)(C)C)CC3)c3cccnc3n(C)c2=O)cc(OC)c1 CHEMBL4646540 IC50 130.0 nM
Cc1cccc(C)c1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4202436 IC50 150.0 nM
Fc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 CHEMBL4206801 IC50 160.0 nM
Cc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 CHEMBL4205965 IC50 190.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCc2ccccc2)c2ccccc2n(C)c1=O CHEMBL4634697 IC50 210.0 nM
CCc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4217275 IC50 240.0 nM
COc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4211357 IC50 240.0 nM
Clc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4202973 IC50 270.0 nM
COc1cc(CN(C)C(=O)c2c(OCCCC3CCN(C(=O)OC4(C)CC4)CC3)c3cccnc3n(C)c2=O)cc(OC)c1 CHEMBL4644293 IC50 300.0 nM
c1ccc(COc2cccc3onc(Nc4cccnc4)c23)cc1 CHEMBL4212291 IC50 340.0 nM
CC(C)CCOc1c(C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(=O)n(C)c2ccccc12 CHEMBL4637599 IC50 350.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCOCc2ccccc2)c2ccccc2n(C)c1=O CHEMBL4649105 IC50 380.0 nM
CCOc1cc(CN(C)C(=O)c2c(OCCCC3CCN(C(=O)OC(C)(C)C)CC3)c3ccccc3n(C)c2=O)cc(OCC)c1 CHEMBL4639746 IC50 380.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(N2CCCC2)c2ccccc2n(C)c1=O CHEMBL4162182 IC50 410.0 nM
CCCCCCCOc1ccc(Cl)cc1COc1ccccc1C(=O)Nc1cccnc1 CHEMBL4544787 IC50 430.0 nM
Cc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4217676 IC50 470.0 nM
O=C(Nc1cccnc1)c1ccccc1OCc1ccccc1OCCCCCCCl CHEMBL4472866 IC50 470.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(OCCCC2CCCCC2)c2ccccc2n(C)c1=O CHEMBL4638097 IC50 480.0 nM
COc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 CHEMBL4216327 IC50 520.0 nM
CCCCCCOc1ccc(Cl)cc1COc1ccccc1C(=O)Nc1cccnc1 CHEMBL4452926 IC50 520.0 nM
CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(N2CCC(OCc3ccccc3)C2)c2ccccc2n(C)c1=O CHEMBL4644982 IC50 610.0 nM
Fc1ccccc1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4211679 IC50 670.0 nM
COc1ccc(Cl)cc1COc1ccccc1C(=O)Nc1cccnc1 CHEMBL4448125 IC50 670.0 nM
O=C(Nc1cccnc1)c1ccccc1OCc1ccccc1OCCCCCCl CHEMBL4558411 IC50 670.0 nM
O=C(Nc1cccnc1)c1ccccc1OCc1c(Cl)cccc1Cl CHEMBL4559796 IC50 690.0 nM
Fc1cccc(F)c1COc1cccc2onc(Nc3cccnc3)c12 CHEMBL4210244 IC50 740.0 nM
O=C(Nc1cccnc1)c1ccccc1OCc1cc(F)ccc1Cl CHEMBL4462317 IC50 740.0 nM
Cc1ccc(F)cc1COc1ccccc1C(=O)Nc1cccnc1 CHEMBL4565783 IC50 740.0 nM
Cc1cccc(C)c1COc1ccccc1C(=O)Nc1cccnc1 CHEMBL4568145 IC50 890.0 nM
N#Cc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1 CHEMBL4203583 IC50 960.0 nM
O=C(Nc1cccnc1)c1ccccc1OCc1cc(Cl)ccc1Cl CHEMBL4450070 IC50 990.0 nM
O=C(CCCCCCCCc1ccccc1)c1c(O)cccc1O CHEMBL1254269 IC50 1000.0 nM
O=C(CCCCCCCCc1ccc(O)cc1)c1c(O)cccc1O CHEMBL489354 IC50 1000.0 nM
O=C(CCCCCCCCc1ccc(O)c(O)c1)c1c(O)cccc1O CHEMBL524100 IC50 1000.0 nM