O=c1sc2cc(CCCF)ccc2n1CCN1CCCCCC1 CHEMBL2181924 Ki 0.0025 nM
CC(Cc1ccc(C(C)(C)C)cc1)CN1C[C@@H](C)O[C@@H](C)C1 CHEMBL372700 Ki 0.01 nM
c1ccc(CN2CCC3(CC2)OCC(c2ccccc2)CO3)cc1 CHEMBL5432062 Ki 0.013 nM
CC1CCN(CCCCc2cccc3cc(OCCCCCCN4C(=O)c5ccc(N(C)C)cc5C4=O)ccc23)CC1 CHEMBL3763396 Ki 0.03 nM
c1ccc2c(c1)CCCC2CCCCN1CCN(C2CCCCC2)CC1 CHEMBL76758 Ki 0.036 nM
CCCCCCCCCCCCCN1C[C@@H](C)O[C@@H](C)C1 CHEMBL365842 Ki 0.04 nM
O=C(OCCN1CCC(c2ccccc2)CC1)C1(c2ccc([N+](=O)[O-])cc2)CCCC1 CHEMBL541284 Ki 0.05 nM
O=C1CC(C2CCN(Cc3ccccc3)CC2)Sc2ccccc21 CHEMBL578825 pKi 0.05248 nM
c1ccc(CN2CCC(C3CCc4ccccc4S3)CC2)cc1 CHEMBL570795 pKi 0.05754 nM
O=C1CC(C2CCN(Cc3ccccc3)CC2)Oc2ccccc21 CHEMBL570529 pKi 0.06607 nM
CC1CCN(CCCCCc2ccccc2)CC1 CHEMBL304079 Ki 0.07 nM
CCCN1CCC=C(c2cc(-c3ccc(C)cc3)no2)C1 CHEMBL4088272 Ki 0.08 nM
c1ccc(CN2CCC3(CC2)OCc2ccccc2S3)cc1 CHEMBL571418 pKi 0.08913 nM
CC1CCN(CCCCC(c2ccccc2)c2ccccc2)CC1 CHEMBL302087 Ki 0.09 nM
c1ccc(CN2CCC3(CC2)OCc2ccccc2O3)cc1 CHEMBL572294 pKi 0.09772 nM
O=C1CC(C2CCN(CCc3ccccc3)CC2)Oc2ccccc21 CHEMBL570067 pKi 0.1096 nM
CC1CCN(CCCC=C(c2ccccc2)c2ccccc2)CC1 CHEMBL67808 Ki 0.13 nM
CN(CCN1CCCCCC1)S(=O)(=O)c1ccc(I)cc1 CHEMBL81455 Ki 0.14 nM
c1ccc(CCCCCNCCc2ccccc2)cc1 CHEMBL19355 Ki 0.17 nM
CN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCCCC1 CHEMBL356688 Ki 0.17 nM
CN(CCN1CCCCCC1)S(=O)(=O)c1ccc(Br)cc1 CHEMBL309983 Ki 0.18 nM
CN(CCCCCc1ccccc1)Cc1ccccc1 CHEMBL19314 Ki 0.19 nM
CN(C)[C@@]1(C)Cc2ccccc2[C@H](c2ccccc2)C1 CHEMBL542167 IC50 0.2 nM
O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL54 Ki 0.2 nM
OCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1 CHEMBL370753 Ki 0.2 nM
O=C1CC2(CCN(Cc3ccccc3)CC2)Oc2ccccc21 CHEMBL571659 pKi 0.2089 nM
c1ccc2c(CCCCN3CCN(C4CCCCC4)CC3)cccc2c1 CHEMBL306133 Ki 0.22 nM
CN(CCCCCc1ccccc1)CCc1ccccc1 CHEMBL19544 Ki 0.25 nM
c1ccc2c(c1)CC[C@H]1CN(C3CCCCC3)CC[C@@H]21 CHEMBL553265 Log IC50 0.2512 nM
CN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCCC1 CHEMBL142700 Ki 0.26 nM
CN(C)CCCCCC1CCCCC1 CHEMBL20036 Ki 0.26 nM
O=C(OCCCN1CCC(c2ccccc2)CC1)C1(c2ccc([N+](=O)[O-])cc2)CCCC1 CHEMBL542131 Ki 0.27 nM
c1ccc(C(c2ccc(N3CCN(C4CCCCC4)CC3)cc2)C23CC4CC(CC(C4)C2)C3)cc1 CHEMBL2023825 IC50 0.27 nM
c1ccc(CCCCCNCCCc2ccccc2)cc1 CHEMBL19638 Ki 0.28 nM
CN(C)C1Cc2cc(Cl)c(O)cc2C(c2ccccc2)C1 CHEMBL317029 Log IC50 0.2884 nM
CCCCCN1CC[C@@]2(C)c3cc(O)ccc3CC1[C@H]2C CHEMBL324392 Ki 0.29 nM
CN(C)[C@H]1Cc2cc(Cl)c(O)cc2[C@H](c2ccccc2)C1 CHEMBL545477 IC50 0.29 nM
CCCN(C)CCCCCc1ccccc1 CHEMBL20348 Ki 0.29 nM
c1ccc(CN2CCN(CC3COc4ccccc4C3)CC2)cc1 CHEMBL362699 Ki 0.3 nM
O=C1CC(CN2CCN(Cc3ccccc3)CC2)Cc2ccccc21 CHEMBL360351 Ki 0.3 nM
c1ccc(CN2CCN(CC3CCc4ccccc4O3)CC2)cc1 CHEMBL179648 Ki 0.3 nM
CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL70807 Ki 0.31 nM
COc1cccc2c1CCCC2CN1CCN(C2CCCCC2)CC1 CHEMBL75878 Ki 0.31 nM
CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1 CHEMBL342809 Ki 0.32 nM
c1ccc(CCCCCNCc2ccccc2)cc1 CHEMBL19315 Ki 0.32 nM
c1ccc(CCN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL540274 Log IC50 0.3236 nM
CN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL20377 Ki 0.34 nM
CC1CCN([C@@H](C)COc2ccc(Cl)cc2)CC1 CHEMBL555790 Ki 0.34 nM
COc1ccc2c(c1)CCCC2CCCN1CCN(C2CCCCC2)CC1 CHEMBL77906 Ki 0.36 nM
CN(CCN1CCCC1)Cc1ccc(Cl)c(Cl)c1 CHEMBL143089 Ki 0.38 nM
CN(CCCCCc1ccccc1)CCCc1ccccc1 CHEMBL19637 Ki 0.38 nM
COc1cccc2c1CCCC2CCCN1CCN(C2CCCCC2)CC1 CHEMBL53325 Ki 0.38 nM
FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL70540 Ki 0.39 nM
COc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 CHEMBL165848 Ki 0.39 nM
CCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1 CHEMBL596 Ki 0.39 nM
COc1cccc2c1CCCC2N1CCN(C2CCCCC2)CC1 CHEMBL309064 Ki 0.4 nM
O=C1c2ccccc2CCC1CN1CCN(Cc2ccccc2)CC1 CHEMBL425867 Ki 0.4 nM
c1ccc(CN2CCC3(CCc4ccccc4C3)CC2)cc1 CHEMBL570789 pKi 0.4365 nM
COc1ccc(C2=CCN(CCCCc3ccncc3)CC2)cc1 CHEMBL94801 Ki 0.45 nM
Clc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 CHEMBL164124 Ki 0.46 nM
O=S(=O)(NCCN1CCCCC1)c1ccc(I)cc1 CHEMBL81500 Ki 0.46 nM
COc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 CHEMBL163876 Ki 0.47 nM
CN(CCCCC(c1ccccc1)c1ccccc1)CCc1ccccc1 CHEMBL69256 Ki 0.48 nM
c1ccc(CCCCCN2CCCCC2)cc1 CHEMBL20188 Ki 0.48 nM
c1ccc(CCCCCNCCCCc2ccccc2)cc1 CHEMBL20153 Ki 0.48 nM
Clc1ccc(CCN[C@@H]2CCCC[C@@H]2N2CCCC2)cc1Cl CHEMBL104834 Ki 0.49 nM
c1ccc(CCCCN2CCC(Cc3ccccc3)CC2)cc1 CHEMBL276784 Ki 0.49 nM
c1ccc(CN2CCC3(CCc4ccccc4S3)CC2)cc1 CHEMBL39900 Ki 0.5 nM
O=C(OCCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 CHEMBL540013 Ki 0.5 nM
O=C(CCN1CC=C(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL129452 IC50 0.5 nM
C[C@@H](Cc1ccccc1)NCCCCCc1ccccc1 CHEMBL20700 Ki 0.5 nM
c1ccc(CCCN2CCN(CCCc3ccccc3)CC2)cc1 CHEMBL346409 IC50 0.5 nM
Clc1ccccc1CNC[C@H]1CC[C@H](CCNc2ccccc2Cl)CC1 CHEMBL361085 Ki 0.5 nM
CC(C)CCCC(C)CCCC(C)N1CC[C@H]2[C@H](C)[C@@H](O)CC[C@]2(C)C1 CHEMBL17470 Ki 0.5 nM
c1ccc(CC2CCN(CC3CSCS3)CC2)cc1 CHEMBL4643239 Ki 0.5 nM
CC1(C)SCC(CN2CCC(Cc3ccccc3)CC2)S1 CHEMBL4650902 Ki 0.5 nM
O=C(OCCCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 CHEMBL542630 Ki 0.51 nM
CCN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL141501 Ki 0.51 nM
FCCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL312766 Ki 0.52 nM
CN(C)C1Cc2ccccc2C(c2ccccc2)C1 CHEMBL104945 Log IC50 0.5248 nM
CN(CCc1cc(Cl)c(Cl)cc1I)CCN1CCCC1 CHEMBL71049 Ki 0.54 nM
CCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL310240 Ki 0.55 nM
Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1Cl CHEMBL162807 Ki 0.58 nM
O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1CCCCCCN1CCC(c2ccccc2)CC1 CHEMBL304506 Ki 0.59 nM
FCCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL1645202 Ki 0.59 nM
CCCc1ccc2c(c1)sc(=O)n2CCN1CCCCC1 CHEMBL274699 Ki 0.6 nM
CCCCN1CCC2(CCCc3ccccc32)CC1 CHEMBL62540 Ki 0.6 nM
CN(CCCn1c(=O)sc2cc(Br)ccc21)Cc1ccccc1 CHEMBL3409378 Ki 0.6 nM
CC1(C)SCC(CN2CCN(Cc3ccccc3)CC2)S1 CHEMBL4633444 Ki 0.6 nM
CC1(C)OCC(CN2CCC(Cc3ccccc3)CC2)O1 CHEMBL4646948 Ki 0.6 nM
O=C(OCCCCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 CHEMBL542380 Ki 0.61 nM
c1ccc2c(c1)CCCC2CCCN1CCN(C2CCCCC2)CC1 CHEMBL75608 Ki 0.61 nM
c1ccc(CN2CCC3(CCc4ccccc4O3)CC2)cc1 CHEMBL38634 pKi 0.6166 nM
C[C@@H](CN1CCCC1)N(C)CCc1ccc(Cl)c(Cl)c1 CHEMBL347514 Ki 0.62 nM
O=S(=O)(NCCN1CCCCCC1)c1ccc(Br)cc1 CHEMBL79660 Ki 0.63 nM
COc1ccc(C2(C(=O)OCCCN3CCC(c4ccccc4)CC3)CCCC2)cc1 CHEMBL537464 Ki 0.65 nM
c1ccc(CCNCCCCC(c2ccccc2)c2ccccc2)cc1 CHEMBL303263 Ki 0.66 nM
N#Cc1ccc(OCC2CCN(C/C=C/I)CC2)cc1 CHEMBL274585 Ki 0.67 nM
CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 CHEMBL318877 Ki 0.67 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1 CHEMBL143103 Ki 0.67 nM
N#Cc1ccc(OCC2CCN(C/C=C/[123I])CC2)cc1 CHEMBL2347004 Ki 0.67 nM
c1ccc(CN2CCC3(CC2)OCCc2ccccc23)cc1 CHEMBL138083 Ki 0.69 nM
Oc1ccc2c(c1)CCCC2CCCN1CCN(C2CCCCC2)CC1 CHEMBL73964 Ki 0.69 nM
COc1c(C(=O)N[C@@H]2CCN(C3CCCC3)C2)cc(Br)c2ccccc12 CHEMBL54027 Ki 0.7 nM
O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1CCCCCN1CCC(c2ccccc2)CC1 CHEMBL177829 Ki 0.7 nM
Fc1cc(COC2CCN(Cc3ccc4[nH]ncc4c3)CC2)ccc1Cl CHEMBL5198353 Ki 0.7 nM
FC(F)(F)c1cccc(COC2CCN(Cc3ccc4[nH]ncc4c3)CC2)c1 CHEMBL5196213 pKi 0.7079 nM
O=[N+]([O-])c1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 CHEMBL144741 Ki 0.72 nM
c1ccc(CN2CCC3(CCc4ccccc43)CC2)cc1 CHEMBL1788383 Log IC50 0.7244 nM
CCN(CC)CCN(C)CCc1ccc(Cl)c(Cl)c1 CHEMBL143178 Ki 0.73 nM
c1ccc(CN2CCN(CC3COC4(CCCCC4)O3)CC2)cc1 CHEMBL3769930 Ki 0.74 nM
c1ccc(CCCCCN2CCCC2)cc1 CHEMBL277462 Ki 0.76 nM
c1ccc(CCCCN2CCC(c3ccccc3)CC2)cc1 CHEMBL325238 Ki 0.8 nM
CC1CCN(CCC=C2c3ccccc3Sc3ccccc32)CC1 CHEMBL305218 Ki 0.8 nM
c1ccc(CN2CCN(CC3CCc4ccccc4C3)CC2)cc1 CHEMBL369091 Ki 0.8 nM
c1ccc(CNCCCCCC2CCCCC2)cc1 CHEMBL416730 Ki 0.81 nM
C[C@H](CN1CCCC1)N(C)CCc1ccc(Cl)c(Cl)c1 CHEMBL422834 Ki 0.83 nM
O=C(CCCN1CCC(O)(c2cccc(C(F)(F)F)c2)CC1)c1ccc(F)cc1 CHEMBL15023 Ki 0.83 nM
CN(CCc1cccc(Cl)c1)CCN1CCCC1 CHEMBL142596 Ki 0.84 nM
CC1CCN(CCOc2ccc(Cl)cc2)CC1 CHEMBL543821 Ki 0.86 nM
C(/C=C/c1ccc2c(c1)OCO2)=C\CN1CCCCC1 CHEMBL418484 Ki 0.86 nM
O=C(Cc1cccc(Br)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL77405 Ki 0.87 nM
O=C(OCCCN1CCC(c2ccccc2)CC1)C1(c2ccc(I)cc2)CCCC1 CHEMBL556409 Ki 0.88 nM
CN(CCCC=C(c1ccccc1)c1ccccc1)CCc1ccccc1 CHEMBL71155 Ki 0.89 nM
c1ccc(CCCCCN2CCC(c3ccccc3)CC2)cc1 CHEMBL112474 Ki 0.9 nM
C[C@H](Cc1ccccc1)NCCCCCc1ccccc1 CHEMBL280160 Ki 0.9 nM
O=C1[C@@H]2Cc3ccccc3CN2C(=S)N1CCN1CCCCC1 CHEMBL193805 IC50 0.9 nM
CN(CCCn1c(=O)oc2cc(Br)ccc21)Cc1ccccc1 CHEMBL3409374 Ki 0.9 nM
Clc1ccc(CCCOCCCN2CCCCC2)cc1 CHEMBL4164059 Ki 0.9043 nM
COc1ccc(CN2CC3CCCC2CN3Cc2ccccc2)cc1 CHEMBL3086334 Ki 0.91 nM
c1ccc(CC2CCN(CCOc3ccccc3)CC2)cc1 CHEMBL102659 Ki 0.93 nM
C[C@H]1[C@H]2Cc3ccccc3[C@@H]1CCN2Cc1ccccc1 CHEMBL140618 Ki 0.96 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(F)cc1 CHEMBL157335 Ki 0.97 nM
Clc1ccc(CCN2CCN3CCCCC3C2)cc1Cl CHEMBL309062 Ki 0.98 nM
O=C1O[C@@H](CN2CCC(O)(c3ccc4c(c3)OCO4)CC2)CN1c1ccc(OC(F)(F)F)cc1 CHEMBL45535 Ki 1.0 nM
C(#Cc1ccccc1)COCCC1CCN(CC2CC2)CC1 CHEMBL75678 Ki 1.0 nM
O=C1c2ccccc2CCC12CCN(Cc1ccccc1)CC2 CHEMBL554874 Ki 1.0 nM
O=C1CC2(CCN(CCc3ccccc3)CC2)OC=C1c1ccccc1F CHEMBL542400 Ki 1.0 nM
O=C(c1ccc(F)cc1)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 CHEMBL51 Log IC50 1.0 nM
Fc1ccc(C(OCCN2CCN(CCCc3ccccc3)CC2)c2ccc(F)cc2)cc1 CHEMBL281594 Log IC50 1.0 nM
O=C1C=C(c2ccccc2)OC12CCN(Cc1ccccc1)CC2 CHEMBL553500 Ki 1.0 nM
O=C1C(c2ccccc2)=COC12CCN(CC1CCCCC1)CC2 CHEMBL544996 Ki 1.0 nM
O=C1C=C(c2ccccc2)OC12CCN(CCc1ccccc1)CC2 CHEMBL545222 Ki 1.0 nM
CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1 CHEMBL633 Ki 1.0 nM
CC(C)[C@](C#N)(CCCN(C)CCc1ccccc1)c1ccccc1 CHEMBL187615 Ki 1.0 nM
CCCCCCCCCCCCC(C#N)(CCCN(C)CCc1ccccc1)c1ccccc1 CHEMBL363884 Ki 1.0 nM
CCN(CC)CCO[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]32)C1 CHEMBL365141 Ki 1.0 nM
CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1 CHEMBL190883 Ki 1.0 nM
COc1ccc(C2(C(=O)OCCN3CCC(c4ccccc4)CC3)CCCC2)cc1 CHEMBL543808 Ki 1.02 nM
Clc1ccc(C2=CCN(CCCCc3ccncc3)CC2)cc1 CHEMBL93442 Ki 1.04 nM
CC(C)=CCN1CCC2(CCCc3ccccc32)CC1 CHEMBL62770 Log IC50 1.047 nM
CC1(C)C2CC[C@@]1(C)CN(CC1CCCCC1)C2 CHEMBL308816 Ki 1.08 nM
CC1CCN(C[C@H](C)COc2ccc(Cl)cc2)CC1 CHEMBL539776 Ki 1.09 nM
COc1c(C(=O)NC2CCN(C3CCCCCC3)CC2)cc(Br)c2ccccc12 CHEMBL53078 Ki 1.1 nM
COc1c(C(=O)NC2CCN(C3CCCCC3)CC2)cc(Br)c2ccccc12 CHEMBL51856 Ki 1.1 nM
c1ccc(CCCN2CCC(c3ccccc3)CC2)cc1 CHEMBL112124 Ki 1.1 nM
CC1CCN(CCCC(c2ccccc2)c2ccccc2)CC1 CHEMBL71883 Ki 1.1 nM
CN(CCCNC(=O)c1ccc(Cl)c(Cl)c1)Cc1ccccc1 CHEMBL4161984 Ki 1.1 nM
Cc1nc(-c2ccc(Cl)cc2)nc(OCCCN2CCCCC2)c1Cl CHEMBL3359239 Ki 1.1 nM
c1ccc(CC2CCN(CCCOc3ccccc3)CC2)cc1 CHEMBL5403125 Ki 1.1 nM
Clc1ccc(CCNCCN2CCCC2)cc1Cl CHEMBL142755 Ki 1.11 nM
COC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL138809 Ki 1.14 nM
O=C(Cc1cccc(Cl)c1)NC1CCN(Cc2ccc(F)cc2)CC1 CHEMBL139340 Ki 1.15 nM
CC(C)=CCN1CC[C@H]2c3ccccc3CC[C@H]2C1 CHEMBL544281 Log IC50 1.175 nM
CC(C)=CCN1CCC2(CCc3ccccc32)CC1 CHEMBL1788382 Log IC50 1.175 nM
CC1CCN([C@H](C)COc2ccc(Cl)cc2)CC1 CHEMBL542873 Ki 1.18 nM
Clc1ccc(CCN2CCN(CCCI)CC2)cc1Cl CHEMBL420557 Ki 1.19 nM
O=[N+]([O-])c1ccc(OCC2CCN(Cc3ccc(F)cc3)CC2)cc1 CHEMBL46596 Ki 1.2 nM
COc1c(C(=O)N[C@@H]2CCN(C3CCCCC3)C2)cc(Br)c2ccccc12 CHEMBL54026 Ki 1.2 nM
COc1c(C(=O)NC2CCN(C3CCCC3)CC2)cc(Br)c2ccccc12 CHEMBL54092 Ki 1.2 nM
O=[N+]([O-])c1ccccc1CCN1CCN(CCCc2ccccc2)CC1 CHEMBL356582 Ki 1.2 nM
CC1(C)C2CC[C@]1(C)CN(CCCCC1CCCCC1)C2 CHEMBL74803 Ki 1.2 nM
O=C1CC(CN2CCN(Cc3ccccc3)CC2)Oc2ccccc21 CHEMBL180180 Ki 1.2 nM
CN(CCCn1c(=O)oc2ccc(Br)cc21)Cc1ccccc1 CHEMBL3409373 Ki 1.2 nM
CN(CCNC(=O)c1ccc(C#N)cc1)Cc1ccccc1 CHEMBL4172201 Ki 1.2 nM
CCCCN1CCC2(CCCc3ccccc32)CC1 CHEMBL1788381 Log IC50 1.202 nM
Cn1ncc2cc(CN3CCC(OCc4ccc(F)c(F)c4)CC3)ccc21 CHEMBL5209344 pKi 1.202 nM
O=C(Cc1cccc(Br)c1)NC1CCN(Cc2ccc(F)cc2)CC1 CHEMBL334568 Ki 1.21 nM
O=C(OCCCCCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 CHEMBL539252 Ki 1.21 nM
CN(Cc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@H]1N1CCCC1 CHEMBL101909 Ki 1.24 nM
CN(C)CCN(C)CCc1ccc(Cl)c(Cl)c1 CHEMBL143360 Ki 1.26 nM
COC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL141209 Ki 1.29 nM
CN(CCc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@H]1N1CCCC1 CHEMBL106437 Ki 1.3 nM
CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1 CHEMBL521582 IC50 1.3 nM
CN1CCC2(c3cccc(O)c3)CC(=O)/C(=C/c3ccccc3)C1C2 CHEMBL110319 Ki 1.3 nM
N#Cc1ccc(C2(C(=O)OCCN3CCC(c4ccccc4)CC3)CCCC2)cc1 CHEMBL545678 Ki 1.3 nM
C(CCCNCCc1ccccc1)=C(c1ccccc1)c1ccccc1 CHEMBL304283 Ki 1.3 nM
COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1 CHEMBL144490 Ki 1.3 nM
CN(CCN1CCCC1)C1CCc2cc(Cl)c(Cl)cc2C1 CHEMBL308529 Ki 1.3 nM
C[C@H](Cc1ccccc1)N(C)CCCc1ccccc1 CHEMBL20517 Ki 1.3 nM
CN(c1nc2ccccc2s1)C1CCN(CCCCOc2ccccc2)C1 CHEMBL363765 Ki 1.3 nM
CS(=O)(=O)n1cc(CCCCN2CCC3(CC2)OCc2ccccc23)c2ccccc21 CHEMBL64683 Ki 1.3 nM
Cn1ncc2cc(CN3CCC(OCc4ccc(Cl)c(F)c4)CC3)ccc21 CHEMBL5201507 Ki 1.3 nM
c1ccc(CN2CCN(CC3CSC4(CCCCC4)O3)CC2)cc1 CHEMBL4650795 Ki 1.3 nM
O=S(=O)(NCCN1CCCCCC1)c1ccc(I)cc1 CHEMBL439765 Ki 1.32 nM
CC1(C)C2CC[C@]1(C)CN(CC1CCCCC1)C2 CHEMBL424606 Ki 1.33 nM
Clc1cc2c(cc1Cl)CN(CCN1CCCC1)CC2 CHEMBL134313 Ki 1.34 nM
O=C(OCCN1CCC(c2ccccc2)CC1)C1(c2ccc(Cl)cc2)CCCC1 CHEMBL544041 Ki 1.34 nM
c1ccc2c(c1)CCC21CCN(CC2CCCCC2)CC1 CHEMBL1743999 Log IC50 1.349 nM
CCCN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL141945 Ki 1.35 nM
CC1(C)C2CC[C@@]1(C)CN(CCC1CCCCC1)C2 CHEMBL77812 Ki 1.35 nM
C=CCN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL422826 Ki 1.39 nM
O=C1c2ccccc2CCC12CCN(Cc1ccccc1)CC2 CHEMBL41830 Ki 1.4 nM
Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 CHEMBL162422 Ki 1.4 nM
O=C(Cc1cccc(Cl)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL76864 Ki 1.4 nM
CN(C)C1Cc2cc(Cl)c(O)cc2C(c2ccccc2)C1 CHEMBL545249 IC50 1.4 nM
CC1CCN(CC[C@@H](C)Oc2ccc(Cl)cc2)CC1 CHEMBL555090 Ki 1.4 nM
CCN(CC)CCCCC(c1ccccc1)c1ccccc1 CHEMBL305461 Ki 1.4 nM
COc1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 CHEMBL358116 Ki 1.4 nM
Clc1ccc(CCN2CCN3CCC[C@@H]3C2)cc1Cl CHEMBL306586 Ki 1.4 nM
O=C1CC(CN2CCC(Cc3ccccc3)CC2)Oc2ccccc21 CHEMBL179397 Ki 1.4 nM
c1ccc(CC2CCN(CC3Cc4ccccc4C3)CC2)cc1 CHEMBL179145 Ki 1.4 nM
O=C1CC(CN2CCC(Cc3ccccc3)CC2)Cc2ccccc21 CHEMBL369133 Ki 1.4 nM
CN(CCCNC(=O)c1ccc(C(F)(F)F)cc1)Cc1ccccc1 CHEMBL4162490 Ki 1.4 nM
c1ccc(Cc2cn(C3CCN(Cc4ccccc4)CC3)nn2)cc1 CHEMBL4434865 Ki 1.4 nM
c1ccc2c(c1)CCCC1CN(C3CCCCC3)CCC21 CHEMBL555890 Log IC50 1.413 nM
Cc1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1744003 Log IC50 1.413 nM
O=C(OCCN1CCC(c2ccccc2)CC1)C1(c2ccc(I)cc2)CCCC1 CHEMBL554628 Ki 1.44 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1F CHEMBL154039 Ki 1.45 nM
c1ccc2c(c1)CCCC2CCCCCN1CCN(C2CCCCC2)CC1 CHEMBL74080 Ki 1.45 nM
O=S(=O)(NCCN1CCCC1)c1ccc(I)cc1 CHEMBL79840 Ki 1.46 nM
CC(CN(C)CCc1ccc(Cl)c(Cl)c1)N(C)C CHEMBL142297 Ki 1.46 nM
CC1C2Cc3ccc(N)cc3C1(C)CCN2Cc1ccccc1 CHEMBL102406 Ki 1.47 nM
CN(CCc1ccc(Cl)cc1)CCN1CCCC1 CHEMBL358109 Ki 1.47 nM
CCN1CCCC1CN(C)CCc1ccc(Cl)c(Cl)c1 CHEMBL342223 Ki 1.48 nM
CC(C)=CCN1CCC2(C)c3cc(F)ccc3CC1C2C CHEMBL103157 Ki 1.48 nM
CN(CCN(C)Cc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL109026 Ki 1.49 nM
CCCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC CHEMBL553962 IC50 1.5 nM
c1ccc(CCCCCCCNCCc2ccccc2)cc1 CHEMBL19797 Ki 1.5 nM
c1ccc(CC2CCN(CC3CCc4ccccc4C3)CC2)cc1 CHEMBL180327 Ki 1.5 nM
CC(C)(C)c1ccc(CCCN2CCCCC2)cc1 CHEMBL4083034 Ki 1.5 nM
Brc1ccc(Cc2cn(C3CCN(Cc4ccccc4)CC3)nn2)cc1 CHEMBL4567314 Ki 1.5 nM
O=C(OCCCN1CCC(c2ccccc2)CC1)C1(c2ccc(Cl)cc2)CCCC1 CHEMBL545216 Ki 1.51 nM
COC(=O)[C@]1(c2ccccc2)C[C@@H]1CN1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL1774575 Ki 1.51 nM
CCCCCCN1CCC2(CCc3ccccc32)CC1 CHEMBL1744015 Log IC50 1.514 nM
COc1cccc2c1CCCC2CCCCCN1CCN(C2CCCCC2)CC1 CHEMBL306365 Ki 1.52 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(C#N)cc1 CHEMBL153341 Ki 1.53 nM
N#CC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL148276 Ki 1.54 nM
O=S(=O)(NCCN1CCCCC1)c1ccc(Br)cc1 CHEMBL79841 Ki 1.54 nM
COc1cccc2c1CCCC2CCCCN1CCN(C2CCCCC2)CC1 CHEMBL77220 Ki 1.54 nM
CC(C)=CCN1CCC2(C)c3ccccc3CC1C2C CHEMBL330601 Ki 1.57 nM
COc1cccc2c(CCCN3CCN(C4CCCCC4)CC3)cccc12 CHEMBL75286 Ki 1.57 nM
COc1cccc2c1CCCC2CCN1CCN(C2CCCCC2)CC1 CHEMBL74858 Ki 1.57 nM
CCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL311621 Ki 1.6 nM
O[C@H]1C[C@@H]2CN(CC3CCCCC3)[C@H]1CN2Cc1ccccc1 CHEMBL3819489 Ki 1.6 nM
c1ccc2c(c1)CC(CN1CCN(c3ccc4c(c3)OCCO4)CC1)C2 CHEMBL146556 Ki 1.6 nM
CN(CCCNC(=O)c1ccc(C(C)(C)C)cc1)Cc1ccccc1 CHEMBL4168942 Ki 1.6 nM
CN1CCC2(c3cccc(O)c3)CC(=O)/C(=C/c3cccc(I)c3)C1C2 CHEMBL356639 Ki 1.62 nM
O=C(NC1CCN(Cc2ccccc2)CC1)c1ccccc1I CHEMBL46326 Ki 1.64 nM
COc1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1744002 Log IC50 1.66 nM
CC1(C)C2CC[C@]1(C)CN(CCC1CCCC1)C2 CHEMBL73633 Ki 1.67 nM
COc1c(C(=O)N[C@@H]2CCN(C3CCCCCC3)C2)cc(Br)c2ccccc12 CHEMBL53320 Ki 1.7 nM
O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(I)cc1 CHEMBL50112 Ki 1.7 nM
CC1CCN(C[C@@H](C)COc2ccc(Cl)cc2)CC1 CHEMBL543105 Ki 1.7 nM
Clc1ccc(CCN2CCN(CCc3ccc(Cl)c(Cl)c3)CC2)cc1Cl CHEMBL308284 Ki 1.7 nM
CCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL74031 Ki 1.7 nM
CC(C)=CCN1CC[C@]2(C)c3cc(O)ccc3C[C@H]1[C@H]2C CHEMBL60542 Ki 1.7 nM
CC(C)=CCN1CC[C@@]2(C)c3cc(O)ccc3CC1[C@H]2C CHEMBL305593 Ki 1.7 nM
CN(CCCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1 CHEMBL4165285 Ki 1.7 nM
c1ccc(CC2CCN(CC3CSC4(CCCCCC4)S3)CC2)cc1 CHEMBL4634957 Ki 1.7 nM
Cn1ncc2cc(CN3CCC(OCc4cccc(C(F)(F)F)c4)CC3)ccc21 CHEMBL5175548 Ki 1.7 nM
CCc1ccc(C(=O)C(C)CN2CCCCC2)cc1 CHEMBL1902981 Ki 1.704 nM
CN1CCC2(c3cccc(O)c3)CC(=O)/C(=C/c3ccc(I)cc3)C1C2 CHEMBL145422 Ki 1.71 nM
CC1C2Cc3ccc(O)c(Cl)c3C1(C)CCN2Cc1ccccc1 CHEMBL100463 Ki 1.72 nM
C=CCCN1CC[C@H]2c3ccccc3CC[C@H]2C1 CHEMBL545212 Log IC50 1.738 nM
Clc1ccc(CCN2CCC[C@H]2CN2CCCC2)cc1Cl CHEMBL337818 Ki 1.75 nM
CC1C2Cc3ccc(N(C)C)cc3C1(C)CCN2Cc1ccccc1 CHEMBL103816 Ki 1.75 nM
Fc1ccc(C2=CCN(CCCCc3ccncc3)CC2)cc1 CHEMBL421195 Ki 1.75 nM
CC1C2Cc3ccc(O)c(Br)c3C1(C)CCN2Cc1ccccc1 CHEMBL103455 Ki 1.75 nM
CN(CCCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 CHEMBL142336 Ki 1.76 nM
O=C(Cc1cccc(Br)c1)NC1CCN(Cc2ccc(I)cc2)CC1 CHEMBL343752 Ki 1.78 nM
CC1CCN(CCCOc2ccc(Cl)cc2)CC1 CHEMBL540289 Ki 1.78 nM
O=C(CCCN1CCC2(CCc3ccccc32)CC1)c1ccc(F)cc1 CHEMBL341139 Ki 1.8 nM
CCCNC(CCC(C)C)Cc1ccc(OC)c(OCCc2ccccc2)c1 CHEMBL540331 IC50 1.8 nM
O[C@H](CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL129159 Ki 1.8 nM
Fc1ccc(COC2CCN(Cc3ccc4[nH]ncc4c3)CC2)cc1F CHEMBL5203807 Ki 1.8 nM
CC1CCN(C[C@@H](C)Oc2ccc(Cl)cc2)CC1 CHEMBL542392 Ki 1.81 nM
c1ccc(CN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL545682 Log IC50 1.82 nM
CC1CCN(CC[C@H](C)Oc2ccc(Cl)cc2)CC1 CHEMBL543581 Ki 1.83 nM
CCCCN1CCC2=C(Cc3ccccc32)C1 CHEMBL545688 Log IC50 1.862 nM
C1=Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL137979 Ki 1.87 nM
CCCCCCCN1CC[C@]2(C)c3cc(O)ccc3CC1[C@H]2C CHEMBL115998 Ki 1.9 nM
COc1c(C(=O)NC2CCN(C3C4CCCC3CCC4)CC2)cc(Br)c2ccccc12 CHEMBL53401 Ki 1.9 nM
O=C1c2ccccc2CCC12CCN(Cc1ccc([N+](=O)[O-])cc1)CC2 CHEMBL544123 Ki 1.9 nM
CC1CCN(CCC=C(c2ccccc2)c2ccccc2)CC1 CHEMBL72045 Ki 1.9 nM
CN(CCCNC(=O)c1cccc(N(C)C)c1)Cc1ccccc1 CHEMBL4176708 Ki 1.9 nM
COC1Cc2ccccc2C2(CCC(N(C)CC3CCCCC3)CC2)O1 CHEMBL5402927 Ki 1.9 nM
COc1ccc(/C=C2/C(=O)CC3(c4cccc(O)c4)CCN(C)C2C3)cc1 CHEMBL143800 Ki 1.91 nM
COc1ccc(CN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL541052 Log IC50 1.995 nM
O=C1O[C@@H](CN2CCC(O)(c3ccc4c(c3)OCO4)CC2)CN1c1ccc(OCC2CC2)cc1 CHEMBL417353 Ki 2.0 nM
CN(CCc1ccc(Cl)c(Cl)c1)C1CCCCC1N1CCCC1 CHEMBL2303661 IC50 2.0 nM
Cn1c(=O)sc2cc(CCCCN3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)ccc21 CHEMBL15456 Ki 2.0 nM
Cn1c(=O)sc2cc(CCCCN3CCN(Cc4ccccc4)CC3)ccc21 CHEMBL15941 Ki 2.0 nM
Cn1c(=O)sc2cc(CCN3CCC(c4ccccc4)CC3)ccc21 CHEMBL415985 Ki 2.0 nM
Fc1ccc(C#CCOCCC2CCN(CCc3ccccc3)CC2)cc1 CHEMBL308098 Ki 2.0 nM
O=C1c2ccccc2CCC12CCN(CC1CCCCC1)CC2 CHEMBL554437 Ki 2.0 nM
O=C1c2c(F)cc(F)cc2CCC12CCN(CCc1ccccc1)CC2 CHEMBL122165 Ki 2.0 nM
Nc1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 CHEMBL147098 Ki 2.0 nM
O=C1C(c2ccc(F)cc2)=COC12CCN(CC1CCCCC1)CC2 CHEMBL542398 Ki 2.0 nM
CN(CCN1CCCC1)Cc1ccc(I)cc1 CHEMBL154397 Ki 2.0 nM
C[C@H]([C@@H](O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL113830 Ki 2.0 nM
CN(CCCN1CCc2oc3ccccc3c2C1)Cc1ccccc1 CHEMBL3360556 Ki 2.0 nM
CC1(C)SCC(CN2CCC(Cc3ccccc3)CC2)S1 CHEMBL4647871 Ki 2.0 nM
Cc1cc(COCCN2CCCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL4760287 Ki 2.0 nM
Clc1ccc(-n2ccc(COCCN3CCOCC3)n2)cc1Cl CHEMBL4790686 Ki 2.0 nM
Fc1ccc(CN2CCC(n3cc(Cc4ccc(Br)cc4)nn3)CC2)cc1 CHEMBL4547253 Ki 2.0 nM
CCN(C/C=C\c1ccc(C2CCCCC2)c(Cl)c1)C1CCCCC1 CHEMBL4792070 Ki 2.0 nM
CCCCN1CC[C@H]2c3cc(C)cc(C)c3CC[C@H]2C1 CHEMBL544748 Log IC50 2.042 nM
CCCCN1CCC2(CCc3ccccc32)CC1 CHEMBL1744017 Log IC50 2.042 nM
CCN(CC)CCOC(=O)C1(C2CCCCC2)CCCCC1 CHEMBL1123 Ki 2.055 nM
COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1 CHEMBL138458 Ki 2.07 nM
Cc1ccc(CN2CC[C@]3(C)c4cc(O)ccc4C[C@H]2[C@H]3C)cc1 CHEMBL157390 Ki 2.08 nM
CN(CCc1ccc2ccccc2c1)CCN1CCCC1 CHEMBL142353 Ki 2.09 nM
CCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC CHEMBL128860 IC50 2.1 nM
CN(CCCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)CCc1ccccc1 CHEMBL365786 IC50 2.1 nM
c1ccc(CN2CCC3(CC2)OCCc2sccc23)cc1 CHEMBL2064198 Ki 2.1 nM
COC(=O)[C@@]1(c2ccccc2)C[C@H]1CN(C)C12CC3CC(CC(C3)C1)C2 CHEMBL2203549 Ki 2.1 nM
CN(CCCNC(=O)c1ccc(Br)cc1)Cc1ccccc1 CHEMBL4169383 Ki 2.1 nM
c1ccc(CN2CCN(CC3CSCS3)CC2)cc1 CHEMBL4637859 Ki 2.1 nM
c1ccc(CN2CCN(CC3CSCS3)CC2)cc1 CHEMBL4650581 Ki 2.1 nM
C1=C(c2cccs2)CCN(CCCCc2ccncc2)C1 CHEMBL97302 Ki 2.13 nM
CCCCN1CCC2c3ccccc3CCCC2C1 CHEMBL555581 Log IC50 2.138 nM
N#CCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL147316 Ki 2.16 nM
c1ccc2c(CCCN3CCN(C4CCCCC4)CC3)cccc2c1 CHEMBL75480 Ki 2.16 nM
OC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL137990 Ki 2.17 nM
CC1(C)C2CC[C@]1(C)CN(CCC1CCCCC1)C2 CHEMBL75555 Ki 2.17 nM
N#CC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL147151 Ki 2.18 nM
c1ccc2c(c1)CC[C@H]1CN(C3[C@H]4C[C@@H]5C[C@@H](C[C@H]3C5)C4)CC[C@@H]21 CHEMBL544987 Log IC50 2.188 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc([N+](=O)[O-])cc1 CHEMBL154452 Ki 2.19 nM
O[C@@H](CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL129237 Ki 2.2 nM
Clc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1Cl CHEMBL343654 Ki 2.2 nM
CN(CCCN1C(=O)CSc2ccc(Br)cc21)Cc1ccccc1 CHEMBL3409381 Ki 2.2 nM
O[C@@H]1CC[C@H]2CN(CC3CCCCC3)[C@@H]1CN2Cc1ccccc1 CHEMBL3819146 Ki 2.2 nM
CC(C)n1nc(CN2CCCC2)nc1-c1ccc(C(C)(C)C)cc1 CHEMBL4795418 Ki 2.2 nM
O=C(OCCN1CCOCC1)C1(c2ccccc2)CCCCC1 CHEMBL305881 Ki 2.2 nM
CC1CCN([C@H](C)CCOc2ccc(Cl)cc2)CC1 CHEMBL545691 Ki 2.21 nM
OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL54661 Log IC50 2.239 nM
CCN(CC)C1Cc2ccccc2C(c2ccccc2)C1 CHEMBL323287 Log IC50 2.239 nM
Fc1cc(COC2CCN(Cc3cn4ccccc4n3)CC2)ccc1Cl CHEMBL5196102 pKi 2.239 nM
O=C(Cc1cccc(F)c1)NC1CCN(Cc2ccc(I)cc2)CC1 CHEMBL344425 Ki 2.25 nM
c1ccc2c(c1)CC[C@H]1CN(C34C[C@H]5C[C@@H](C3)C[C@@H](C4)C5)CC[C@@H]21 CHEMBL553561 Log IC50 2.291 nM
c1ccc2c(c1)CCCC21CCN(CC2CCCCC2)CC1 CHEMBL1744000 Log IC50 2.291 nM
CCCCCCN1CC[C@@]2(C)c3cc(O)ccc3CC1[C@H]2C CHEMBL116643 Ki 2.3 nM
CN1CCCC(N(C)CCc2ccc(Cl)c(Cl)c2)C1 CHEMBL137348 Ki 2.3 nM
c1ccc(CCCCCCCNCc2ccccc2)cc1 CHEMBL19850 Ki 2.3 nM
C[C@@H]1CN(CCCc2ccc(C(C)(C)C)cc2)C[C@@H](C)O1 CHEMBL4071509 Ki 2.3 nM
O=C(Cc1cccc(Cl)c1)NC1CCN(Cc2cccc(I)c2)CC1 CHEMBL138794 Ki 2.31 nM
COc1ccc(CN2CCC[C@H](OCc3ccc(F)c(C)c3)C2)cc1F CHEMBL5182191 pKi 2.344 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(Cl)cc1 CHEMBL346456 Ki 2.37 nM
c1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL303336 Ki 2.4 nM
Clc1ccc(CCN[C@H]2CCCC[C@H]2N2CCCC2)cc1Cl CHEMBL320828 Ki 2.4 nM
c1ccc2c(CCCCCN3CCN(C4CCCCC4)CC3)cccc2c1 CHEMBL75372 Ki 2.4 nM
O=C1[C@@H]2Cc3ccccc3CN2C(=O)N1C1CCN(Cc2ccccc2)CC1 CHEMBL193699 IC50 2.4 nM
O[C@@H]1C[C@H]2CN(CC3CCCCC3)[C@@H]1CN2Cc1ccccc1 CHEMBL3819437 Ki 2.4 nM
O=C(Cc1cccc(F)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL306768 Ki 2.45 nM
COc1cccc2c1CCC[C@H]2CCCN1CCN(C2CCCCC2)CC1 CHEMBL419822 Ki 2.45 nM
c1ccc2c(c1)CC[C@H]1CN(CC3CC3)CC[C@@H]21 CHEMBL543810 Log IC50 2.455 nM
CC(C)=CCN1CCC2(C)c3c(ccc(O)c3Br)CC1C2C CHEMBL103458 Ki 2.49 nM
COc1c(C(=O)NC[C@@H]2CCCN2C2CCCC2)cc(Br)c2ccccc12 CHEMBL54571 Ki 2.5 nM
C(#Cc1ccccc1)CNC1CCN(Cc2ccccc2)CC1 CHEMBL115934 Ki 2.5 nM
CN(CCc1ccc(I)cc1)CCN1CCCC1 CHEMBL152426 Ki 2.5 nM
CN(CCc1cccc(I)c1)CCN1CCCC1 CHEMBL152057 Ki 2.5 nM
c1ccc(CC2CCN(CC3COc4ccccc4C3)CC2)cc1 CHEMBL179373 Ki 2.5 nM
COc1cc2c(cc1OC)C1Cc3ccc(OC)c(OC)c3CN1CC2 CHEMBL187892 Ki 2.5 nM
CN(CCCN1CCc2oc3ccccc3c2C1)CCc1ccccc1 CHEMBL3360564 Ki 2.5 nM
O=C(Cc1ccc(Cl)c(Cl)c1)OCCN1CCCC1 CHEMBL544992 Ki 2.51 nM
CC1(C)C2CC[C@]1(C)CN(CCCC1CCCCC1)C2 CHEMBL306318 Ki 2.53 nM
CCCN1CC[C@H]2c3ccccc3CC[C@H]2C1 CHEMBL555401 Log IC50 2.57 nM
c1ccc(CCCCN2CCN(c3ccccc3)CC2)cc1 CHEMBL85879 Ki 2.6 nM
C[C@@H](Cc1ccccc1)N(C)CCCCCc1ccccc1 CHEMBL1907650 Ki 2.6 nM
O=[N+]([O-])c1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1 CHEMBL148008 Ki 2.6 nM
NCCN1CCN(CCCc2ccccc2)CC1 CHEMBL148112 Ki 2.6 nM
CN(C/C=C/c1ccccc1)C1CCN(Cc2ccccc2)CC1 CHEMBL112413 Ki 2.6 nM
c1ccc(CCCCNCCc2ccccc2)cc1 CHEMBL280111 Ki 2.6 nM
CC(C)(C)c1ccc(CCCN2CCOCC2)cc1 CHEMBL4090823 Ki 2.6 nM
CC(C)=CCN1CCC2(C)c3c(ccc(O)c3Cl)CC1C2C CHEMBL318954 Ki 2.62 nM
O=c1cc(CN2CCN(Cc3ccccc3)CC2)oc2ccccc12 CHEMBL178988 Ki 2.66 nM
Clc1ccc(CCN2CCCCC(N3CCCC3)C2)cc1Cl CHEMBL136981 Ki 2.67 nM
CC1CCN([C@@H](C)CCOc2ccc(Cl)cc2)CC1 CHEMBL544524 Ki 2.69 nM
CCCC(Cc1ccccc1)NCCCCc1ccccc1 CHEMBL434393 Ki 2.7 nM
N=C(Nc1ccc(I)cc1)NC12CC3CC(CC(C3)C1)C2 CHEMBL299499 Ki 2.7 nM
C1=C(c2ccccc2)CCN(CCCCc2ccncc2)C1 CHEMBL96777 Ki 2.72 nM
Ic1ccc(CN2CCC3(CC2)OCc2ccccc23)cc1 CHEMBL2346997 Ki 2.75 nM
c1ccc(CCN2CCC3(CCc4ccccc43)CC2)cc1 CHEMBL1744014 Log IC50 2.754 nM
O=C(OCCN1CCN(c2ccccc2)CC1)C1(c2ccc([N+](=O)[O-])cc2)CCCC1 CHEMBL555580 Ki 2.78 nM
CCCCCCCCN1CC[C@]2(C)c3cc(O)ccc3CC1[C@H]2C CHEMBL114163 Ki 2.8 nM
c1ccc(CCCN2CCN(c3ccc4ccccc4c3)CC2)cc1 CHEMBL112574 Ki 2.8 nM
O[C@@H]1C[C@@H]2CN(CC3CCCCC3)[C@H]1CN2Cc1ccccc1 CHEMBL3819331 Ki 2.8 nM
C#CCN(C)Cc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C CHEMBL1929421 Ki 2.83 nM
CC1(C)C2CC[C@]1(C)CN(CCC1CCCCCC1)C2 CHEMBL77817 Ki 2.87 nM
CC1(C)C2CC[C@]1(C)CN(CCC1CCCCCCC1)C2 CHEMBL307839 Ki 2.87 nM
CCCCCCN1CCC2(CCCc3ccccc32)CC1 CHEMBL1744001 Log IC50 2.884 nM
Fc1ccc(OCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 CHEMBL1946126 pKi 2.884 nM
O=C(Cc1ccccc1Br)NC1CCN(Cc2ccccc2)CC1 CHEMBL431775 Ki 2.89 nM
COc1ccc(CN2CC[C@]3(C)c4cc(O)ccc4C[C@H]2[C@H]3C)cc1 CHEMBL153193 Ki 2.89 nM
Clc1ccc(N2CCN(CCCc3ccccc3)CC2)cc1 CHEMBL112125 Ki 2.9 nM
CN(CCc1ccc(Br)cc1)CCN1CCCC1 CHEMBL346153 Ki 2.9 nM
CN(CCCCCc1ccccc1)CCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O CHEMBL194738 IC50 2.9 nM
CCN1CCN(c2ccc(C(c3ccccc3)C34CC5CC(CC(C5)C3)C4)cc2)CC1 CHEMBL2023824 IC50 2.9 nM
CN1CCN(CCc2ccc(C(c3ccccc3)C34CC5CC(CC(C5)C3)C4)cc2)CC1 CHEMBL2204672 IC50 2.9 nM
c1ccc(N2CCN(CCC3OCCc4c3cnn4-c3ccccc3)CC2)cc1 CHEMBL3220583 Ki 2.9 nM
CN(CCCNC(=O)c1ccc(Br)cc1F)Cc1ccccc1 CHEMBL4160397 Ki 2.9 nM
CN(CCCNCc1ccc(Cl)cc1)Cc1ccccc1 CHEMBL4174984 Ki 2.9 nM
O=C1O[C@@H](CN2CCC(O)(c3ccc4c(c3)OCO4)CC2)CN1c1ccc(Cl)cc1 CHEMBL47715 Ki 3.0 nM
Cn1c(=O)sc2cc(CCCCN3CCC(c4ccccc4)CC3)ccc21 CHEMBL15986 Ki 3.0 nM
Cn1c(=O)sc2cc(CCN3CCN(Cc4ccccc4)CC3)ccc21 CHEMBL15955 Ki 3.0 nM
OC1(c2ccccc2)CCN(CCCc2ccccc2)CC1 CHEMBL115508 Ki 3.0 nM
COc1ccc(CN2CCC3(CCc4ccccc4C3=O)CC2)cc1 CHEMBL542709 Ki 3.0 nM
O=C1C(c2ccccc2)=COC12CCN(Cc1ccc(F)cc1)CC2 CHEMBL542395 Ki 3.0 nM
CC1(C)C2CC[C@]1(C)CN(C1CCCCC1)C2 CHEMBL74499 Ki 3.0 nM
CC/C(=C(/CC)c1ccc(OCCN(CC)CC)cc1)c1ccc(OCCN(CC)CC)cc1 CHEMBL190631 Ki 3.0 nM
CCN(C/C=C/c1ccc(C2CCCCC2)c(Cl)c1)C1CCCCC1 CHEMBL188476 Ki 3.0 nM
N=C(Nc1ccc(I)cc1)Nc1ccc(I)cc1 CHEMBL4080735 Ki 3.0 nM
CC1OC2(CCN(CCc3ccccc3)CC2)CN(c2cncc(F)c2)C1=O CHEMBL4470425 Ki 3.0 nM
Cc1cc(COCCN2C[C@@H](C)O[C@@H](C)C2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL4759343 Ki 3.0 nM
Fc1cccc(-c2nnn3c2CO[C@@H]2CN(Cc4ccccc4)C[C@H]23)c1 CHEMBL5186915 Ki 3.0 nM
O=C(NC1CCN(Cc2ccccc2)CC1)c1cccc(I)c1 CHEMBL539938 Ki 3.02 nM
C1=C(c2ccc3ccccc3c2)CCN(CCCCc2ccncc2)C1 CHEMBL94950 Ki 3.07 nM
COc1cccc2c1CCCC2CCCCCCN1CCN(C2CCCCC2)CC1 CHEMBL74811 Ki 3.07 nM
O=C(Cc1ccccc1Cl)NC1CCN(Cc2ccccc2)CC1 CHEMBL76564 Ki 3.08 nM
CCCCN1CC[C@@H]2c3ccccc3CC[C@H]2C1 CHEMBL2093874 Log IC50 3.09 nM
FC(F)(F)c1cccc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)c1 CHEMBL5182602 pKi 3.09 nM
CN1CCC2(c3cccc(O)c3)CC(=O)/C(=C/c3cccc(Cl)c3)C1C2 CHEMBL146659 Ki 3.1 nM
Cc1ccc(NC(=N)Nc2ccc(C)cc2)cc1 CHEMBL81602 Ki 3.1 nM
CCN(CCc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@H]1N1CCCC1 CHEMBL103065 Ki 3.1 nM
CN(CCCn1c(=O)sc2ccc(Br)cc21)Cc1ccccc1 CHEMBL3409377 Ki 3.1 nM
CC(C)=CN1CC[C@@]2(C)c3cc(O)ccc3C[C@H]1[C@H]2C CHEMBL5270434 Ki 3.1 nM
Fc1cc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)ccc1Cl CHEMBL5187721 Ki 3.1 nM
COc1ccc(S(=O)(=O)N(C)CCN2CCCCCC2)cc1I CHEMBL83448 Ki 3.11 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(Br)cc1 CHEMBL152652 Ki 3.11 nM
O=C(Cc1ccccc1F)NC1CCN(Cc2ccc(F)cc2)CC1 CHEMBL135083 Ki 3.15 nM
c1ccc2c(c1)CCC21CCN(CC2CCCO2)CC1 CHEMBL1744005 Log IC50 3.162 nM
COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC CHEMBL408867 pKi 3.162 nM
O=C(Cc1ccc(F)c(F)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL308818 Ki 3.17 nM
COc1c(C(=O)N[C@H]2CCN(Cc3ccccc3)C2)cc(Br)c2ccccc12 CHEMBL50465 Ki 3.2 nM
CN1CCC2(c3cccc(O)c3)CC(=O)/C(=C/c3ccc(Cl)c(Cl)c3)C1C2 CHEMBL322468 Ki 3.2 nM
Cc1cc(F)ccc1/N=C(\N)NC12CC3CC(CC(C3)C1)C2 CHEMBL442356 IC50 3.2 nM
CN(CCCCc1ccccc1)CCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O CHEMBL194687 IC50 3.2 nM
CN1CCN(c2ccc(C(c3ccccc3)C34CC5CC(CC(C5)C3)C4)cc2)CC1 CHEMBL2023823 IC50 3.2 nM
O[C@H]1C[C@H]2CN(CC3CCCCC3)[C@@H]1CN2Cc1ccccc1 CHEMBL3819395 Ki 3.2 nM
CN(CCCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1 CHEMBL4173188 Ki 3.2 nM
O=C(Cc1cccc(Cl)c1)NC1CCN(Cc2ccc(I)cc2)CC1 CHEMBL134855 Ki 3.21 nM
O=C(CCC1CCN(Cc2ccccc2)CC1)c1ccc2[nH]ccc2c1 CHEMBL4585990 Ki 3.3 nM
Nc1ccc(CN2CCC(n3cc(Cc4ccc(Br)cc4)nn3)CC2)cc1 CHEMBL4444356 Ki 3.3 nM
CC[C@H]1[C@H]2Cc3ccccc3[C@@H]1CCN2Cc1ccccc1 CHEMBL139900 Ki 3.36 nM
O=C1c2ccccc2CCC1CN1CCC(Cc2ccccc2)CC1 CHEMBL434905 Ki 3.38 nM
O=C1c2ccccc2OCC1CN1CCC(Cc2ccccc2)CC1 CHEMBL178519 Ki 3.38 nM
CCOc1ccc(CC(C)NCCCc2ccccc2)cc1 CHEMBL20768 Ki 3.4 nM
O=C(CCCN1CC[Si](O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL2204343 Ki 3.4 nM
O=C(Cc1ccc(F)cc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL310499 Ki 3.43 nM
O=[N+]([O-])c1ccc(CCN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL545447 Log IC50 3.467 nM
COc1ccc(CN2CCC3(CCc4ccccc43)CC2)cc1 CHEMBL1744016 Log IC50 3.467 nM
FC(F)(F)c1cccc(COC2CCN(Cc3cn4ccccc4n3)CC2)c1 CHEMBL5179198 pKi 3.467 nM
CN(C)C1Cc2ccccc2C(c2ccccc2)C1 CHEMBL553745 IC50 3.47 nM
O=C(Cc1cccc(Br)c1)NC1CCN(Cc2cccc(I)c2)CC1 CHEMBL337796 Ki 3.49 nM
CCN(CCc1ccc(Cl)c(Cl)c1)[C@@H]1CCCC[C@@H]1N1CCCC1 CHEMBL102695 Ki 3.5 nM
Fc1ccc(CN2CCCC23CCN(Cc2cn4ccccc4n2)C3)cc1F CHEMBL5269586 pKi 3.548 nM
Clc1ccc(CCN2CCCC(N3CCCC3)C2)cc1Cl CHEMBL137794 Ki 3.56 nM
O=C(Cc1ccccc1F)NC1CCN(Cc2ccccc2)CC1 CHEMBL76806 Ki 3.56 nM
COc1c(C(=O)N[C@H]2CCN(C3CCCC3)C2)cc(Br)c2ccccc12 CHEMBL53778 Ki 3.6 nM
CN(CCN1CCCC1)Cc1cccc(I)c1 CHEMBL356909 Ki 3.6 nM
CN(CCNC(=O)c1ccc(Cl)cc1)Cc1ccccc1 CHEMBL4176123 Ki 3.6 nM
CN(CCNC(=O)c1ccc([N+](=O)[O-])cc1)Cc1ccccc1 CHEMBL4166905 Ki 3.6 nM
Fc1ccc(CCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 CHEMBL1946253 Ki 3.6 nM
CN(CCc1ccc(Cl)c(Cl)c1)CC1CCCCN1C CHEMBL342942 Ki 3.69 nM
CCCc1ccc(C(=O)NCCCN(C)Cc2ccccc2)cc1 CHEMBL4172301 Ki 3.7 nM
O=c1c(CN2CCN(Cc3ccccc3)CC2)coc2ccccc12 CHEMBL179651 Ki 3.8 nM
CCCN1CCN(c2cccc(C3CCCCN3C(=O)OCc3ccccc3)c2)CC1 CHEMBL5208940 Ki 3.8 nM
c1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1256916 Log IC50 3.802 nM
CC1C2Cc3ccc(F)cc3C1(C)CCN2Cc1ccccc1 CHEMBL101300 Ki 3.81 nM
O=C(Cc1ccc(F)cc1F)NC1CCN(Cc2ccccc2)CC1 CHEMBL76547 Ki 3.87 nM
O=C(Cc1ccccc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL76895 Ki 3.9 nM
CC(Cc1cccc(C(F)(F)F)c1)NCCCc1ccccc1 CHEMBL19841 Ki 3.9 nM
COc1ccccc1CCN1CCN(CCCc2ccccc2)CC1 CHEMBL147779 Ki 3.9 nM
CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL305187 IC50 3.9 nM
Clc1cc2c(cc1Cl)CC(NCCN1CCCC1)CC2 CHEMBL78100 Ki 3.9 nM
CN(CCCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)Cc1ccccc1 CHEMBL365754 IC50 3.9 nM
CN(CCCNC(=O)c1cccc(Br)c1)Cc1ccccc1 CHEMBL4168697 Ki 3.9 nM
O=C(Cc1cccc(C(F)(F)F)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL77953 Ki 3.92 nM
O=C(Cc1cccs1)NC1CCN(Cc2ccccc2)CC1 CHEMBL138688 Ki 3.93 nM
O=C(OCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 CHEMBL544516 Ki 3.95 nM
O=C(Cc1ccccc1)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 CHEMBL335953 Ki 3.97 nM
O=C(Cc1ccc(Br)cc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL77285 Ki 3.97 nM
CCCCN1CCC2=C(CCCc3ccccc32)C1 CHEMBL545217 Log IC50 3.981 nM
C(#Cc1ccccc1)COCC1CCN(Cc2ccccc2)CC1 CHEMBL308185 Ki 4.0 nM
C(#Cc1ccccc1)COC1CCN(CCc2ccccc2)CC1 CHEMBL311508 Ki 4.0 nM
COc1c(C(=O)NC[C@@H]2CCCN2C2CCC2)cc(Br)c2ccccc12 CHEMBL298759 Ki 4.0 nM
c1ccc(N2CCN(CCCc3ccc4ccccc4c3)CC2)cc1 CHEMBL112037 Ki 4.0 nM
O=C1c2ccc(F)cc2CCC1C1CCN(CCc2ccccc2)CC1 CHEMBL331470 Ki 4.0 nM
O=C1c2ccccc2CCC1C1CCN(Cc2ccccc2)CC1 CHEMBL544594 Ki 4.0 nM
O=C1c2ccccc2CCC12CCN(Cc1ccc(F)cc1)CC2 CHEMBL545285 Ki 4.0 nM
O=C(CCN1CC=C(c2ccc(F)cc2)CC1)c1ccccc1 CHEMBL338181 IC50 4.0 nM
N=C(Nc1ccccc1I)NC1CC2CCC1C2 CHEMBL310003 IC50 4.0 nM
CN(C(=O)C#Cc1ccccc1)C1CCN(Cc2ccccc2)CC1 CHEMBL111964 Ki 4.0 nM
O=C1CC2(CCN(Cc3ccccc3)CC2)OC=C1c1ccccc1 CHEMBL544533 Ki 4.0 nM
O=C1C(c2ccc(F)cc2)COC12CCN(Cc1ccccc1)CC2 CHEMBL543344 Ki 4.0 nM
O=C1CC2(CCN(CCc3ccccc3)CC2)OCC1c1ccc(F)cc1 CHEMBL539007 Ki 4.0 nM
O=C1C(c2ccc(F)cc2)=COC12CCN(Cc1ccccc1)CC2 CHEMBL554415 Ki 4.0 nM
O=C1C(c2ccc(F)cc2)=COC12CCN(Cc1ccc(F)cc1)CC2 CHEMBL545695 Ki 4.0 nM
O=C1C(c2ccccc2)=COC12CCN(Cc1ccccc1)CC2 CHEMBL552687 Ki 4.0 nM
CC(C)[C@@](C#N)(CCCN(C)CCc1ccccc1)c1ccccc1 CHEMBL187829 Ki 4.0 nM
c1ccc(-n2ncc3c2CCCC3CCN2CCOCC2)cc1 CHEMBL4286421 Ki 4.0 nM
Clc1ccc(C2=CCN(CCCCc3ccccc3)CC2)cc1 CHEMBL420302 Ki 4.1 nM
Nc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1 CHEMBL146999 Ki 4.1 nM
NCC(=O)N1CCN(CCCc2ccccc2)CC1 CHEMBL440173 Ki 4.1 nM
c1ccc(OCc2cc(OC[C@@H]3CCCN3)no2)cc1 CHEMBL2203551 Ki 4.1 nM
O=C(Cc1ccccc1F)NC1CCN(Cc2ccc(I)cc2)CC1 CHEMBL343580 Ki 4.2 nM
CN(CCCCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)Cc1ccccc1 CHEMBL366167 IC50 4.2 nM
c1ccc(CC2CCN(CC3CSC4(CCCC4)S3)CC2)cc1 CHEMBL4642427 Ki 4.2 nM
O=C(Cc1cc(F)ccc1F)NC1CCN(Cc2ccccc2)CC1 CHEMBL77289 Ki 4.21 nM
FCCCN(CCc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL70861 Ki 4.22 nM
c1ccc(CCCN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL539260 Log IC50 4.266 nM
COc1ccc(CN2CCC[C@H](OCc3cccc(F)c3)C2)cc1F CHEMBL5207898 pKi 4.266 nM
O=C(Cc1cccc(F)c1)NC1CCN(Cc2cccc(I)c2)CC1 CHEMBL136114 Ki 4.29 nM
CN(CCc1ccc([N+](=O)[O-])cc1)CCN1CCCC1 CHEMBL118797 Ki 4.3 nM
CN(CCc1cccc(Br)c1)CCN1CCCC1 CHEMBL151136 Ki 4.3 nM
CC1(C)C2CC[C@]1(C)CN(CCC1C3CC4CC(C3)CC1C4)C2 CHEMBL73818 Ki 4.3 nM
N#Cc1ccc(OCC2CCN(CCCF)CC2)cc1 CHEMBL417001 Ki 4.3 nM
N#Cc1ccc(OCC2CCN(CCC[18F])CC2)cc1 CHEMBL2347003 Ki 4.3 nM
CN(CCCN1CCc2c([nH]c3ccccc23)C1c1ccccc1)Cc1ccccc1 CHEMBL3360554 Ki 4.3 nM
CN(CCCNC(=O)c1ccc([N+](=O)[O-])cc1)Cc1ccccc1 CHEMBL4174797 Ki 4.3 nM
CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1 CHEMBL4169270 Ki 4.3 nM
Clc1ccc(CCN2CCC[C@@H]2CN2CCCC2)cc1Cl CHEMBL343790 Ki 4.34 nM
OC1c2ccccc2CCC12CCN(CCc1ccccc1)CC2 CHEMBL542942 Ki 4.4 nM
COc1cc(CCN2CCN(CCCc3ccccc3)CC2)ccc1O[11CH3] CHEMBL2311153 Ki 4.4 nM
CCCN(C)C1Cc2ccccc2C(c2ccccc2)C1 CHEMBL134109 Log IC50 4.467 nM
CCCN1CCN(c2cccc(C3CCCCN3S(=O)(=O)c3cc(Cl)cc(Cl)c3)c2)CC1 CHEMBL5191108 pKi 4.467 nM
CCN(CC)C1Cc2ccccc2C(c2ccccc2)C1 CHEMBL544309 IC50 4.49 nM
CCCNC(CCC)Cc1ccc(OC)c(OCCc2ccccc2)c1 CHEMBL128799 IC50 4.5 nM
CCc1cccc(NC(=N)Nc2cc(CC)cc(CC)c2Cl)c1 CHEMBL542487 IC50 4.5 nM
CN(CCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)Cc1ccccc1 CHEMBL196587 IC50 4.5 nM
N#CC1Cc2sccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL2064202 Ki 4.5 nM
O=C(Cc1cccc([N+](=O)[O-])c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL311622 Ki 4.56 nM
C=CCN1CC[C@H]2c3ccccc3CC[C@H]2C1 CHEMBL543101 Log IC50 4.571 nM
O=C(Cc1cccc2ccccc12)NC1CCN(Cc2ccccc2)CC1 CHEMBL336037 Ki 4.64 nM
Clc1ccc(CN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL555398 Log IC50 4.677 nM
CC(C)CCN1CCC2(C)c3cc(F)ccc3CC1C2C CHEMBL103156 Ki 4.68 nM
CN(CCCn1c(=O)sc2ccc(Cl)cc21)Cc1ccccc1 CHEMBL3409379 Ki 4.7 nM
CC(C)=CCN1CCC2(C)c3cc(O)ccc3CC1C2C CHEMBL100116 Ki 4.7 nM
CCCCN1CCC2(CCCCc3ccccc32)CC1 CHEMBL1744010 Log IC50 4.786 nM
CCCN1CCN(c2cccc(C3CCCCN3C(=O)/C=C/c3ccccc3)c2)CC1 CHEMBL5183680 pKi 4.786 nM
COc1c(C(=O)N[C@H]2CCN(C3CCCCCC3)C2)cc(Br)c2ccccc12 CHEMBL54667 Ki 4.8 nM
C[C@@H](Cc1ccccc1)N(C)CCc1ccccc1 CHEMBL20302 Ki 4.8 nM
Nc1ccccc1CCN1CCN(CCCc2ccccc2)CC1 CHEMBL147370 Ki 4.8 nM
c1ccc(CC2CCN(CC3CCc4ccccc4O3)CC2)cc1 CHEMBL178650 Ki 4.8 nM
CCn1nc(CN2CCCC2)nc1-c1ccc(C(C)(C)C)cc1 CHEMBL4799774 Ki 4.8 nM
O=C(Cc1ccc(Cl)c(Cl)c1)OCCN1CCCC1 CHEMBL53649 Ki 4.89 nM
O=C1C(CCN2CCCN(c3ccc(Cl)cc3)CC2)=Cc2cc(Cl)ccc21 CHEMBL4556093 Ki 4.9 nM
CCN(CC)CCNS(=O)(=O)c1ccc(I)cc1 CHEMBL81451 Ki 4.97 nM
O=C1O[C@@H](CN2CCC(O)(c3ccc4c(c3)OCO4)CC2)CN1c1ccccc1 CHEMBL47774 Ki 5.0 nM
Cn1c(=O)sc2cc(CCN3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)ccc21 CHEMBL15601 Ki 5.0 nM
Cn1c(=O)sc2cc(CCCCN3CCC(Cc4ccccc4)CC3)ccc21 CHEMBL16123 Ki 5.0 nM
Cn1c(=O)sc2cc(CCN3CCC(Cc4ccccc4)CC3)ccc21 CHEMBL15809 Ki 5.0 nM
C(=C/c1ccccc1)\COCC1CCN(CC2CC2)CC1 CHEMBL77204 Ki 5.0 nM
C(=C/c1ccccc1)\COCC1CCN(CCc2ccccc2)CC1 CHEMBL77206 Ki 5.0 nM
O=C1c2cccc(F)c2CCC1C1CCN(CCc2ccccc2)CC1 CHEMBL543889 Ki 5.0 nM
N=C(Nc1ccccc1I)NC12CC3CC(CC(C3)C1)C2 CHEMBL553896 IC50 5.0 nM
CN(C(=O)/C=C/c1ccccc1)C1CCN(Cc2ccccc2)CC1 CHEMBL325063 Ki 5.0 nM
CN(CC#Cc1ccccc1)C1CCN(Cc2ccccc2)CC1 CHEMBL112957 Ki 5.0 nM
O=C1CC2(CCN(CCc3ccccc3)CC2)OC=C1c1ccccc1 CHEMBL538755 Ki 5.0 nM
CCN(CC)CCOc1ccc(/C(=C(\Cl)c2ccccc2)c2ccccc2)cc1 CHEMBL167779 Ki 5.0 nM
COc1ccc2c(c1)[C@@H]1CCCN(Cc3ccccc3)[C@H]1CC2 CHEMBL190422 Ki 5.0 nM
CN(CCCCCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)Cc1ccccc1 CHEMBL194796 IC50 5.0 nM
Clc1ccc(-n2cc(NCCN3CCCCC3)nn2)cc1Cl CHEMBL3417042 Ki 5.0 nM
Cc1cc(CCCN2CCOCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL4762627 Ki 5.0 nM
c1ccc(CCN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1744009 Log IC50 5.012 nM
N=C(NCCCCCN1CCCC1)NCC1CCCCC1 CHEMBL308633 Log Ki 5.012 nM
COc1c(C(=O)CCC2CCN(CC3CCCCC3)CC2)cc(Cl)c2[nH]ccc12 CHEMBL4537101 Ki 5.1 nM
O=C(CCC1CCN(CC2CCCCC2)CC1)c1cc(Cl)c2[nH]ccc2c1 CHEMBL4444843 Ki 5.1 nM
O/N=C(\CCCN1CCCN(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL4566049 Ki 5.1 nM
Fc1ccc(COC2CCN(Cc3cn4ccccc4n3)CC2)cc1F CHEMBL5208124 pKi 5.129 nM
N=C(Nc1ccccc1I)NC1C2CC3CC(C2)CC1C3 CHEMBL553347 IC50 5.2 nM
Cc1cc(OCCN2CCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170226 Ki 5.2 nM
CN1CCN(Cc2ccc(C(c3ccccc3)C34CC5CC(CC(C5)C3)C4)cc2)CC1 CHEMBL2204668 IC50 5.2 nM
COc1ccc(CO[C@H]2CCCN(Cc3ccc(C)cc3)C2)cc1F CHEMBL5287836 Ki 5.2 nM
O=C(Cc1ccc(Cl)c(Cl)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL77286 Ki 5.22 nM
Clc1ccccc1CN1CCN(Cc2ccccc2)CC1 CHEMBL349288 Ki 5.3 nM
COc1cccc(CCN2CCN(CCc3cccc(OC)c3)CC2)c1 CHEMBL146546 Ki 5.3 nM
O=C1C2Cc3ccccc3CN2C(=O)N1CCCN1Cc2ccccc2C1 CHEMBL3360552 Ki 5.3 nM
O=C1[C@@H]2Cc3ccccc3CN2C(=O)N1CCCN1Cc2ccccc2C1 CHEMBL3409372 Ki 5.3 nM
CCCN1CCN(c2cccc(C3CCCCN3C(=O)OCc3cc(Cl)cc(Cl)c3)c2)CC1 CHEMBL5197224 pKi 5.37 nM
Fc1ccc(CN2CCCC23CCN(Cc2cc4ccc(Cl)cc4[nH]2)C3)cc1F CHEMBL5274285 pKi 5.37 nM
CN(C)c1ccc2c(c1)C(=O)N(Oc1cccc3c1CCCC3CCCN1CCN(C3CCCCC3)CC1)C2=O CHEMBL5272035 Ki 5.37 nM
FC(F)(F)c1cccc(N2CCN(CCCCc3ccccc3)CC2)c1 CHEMBL114477 Ki 5.4 nM
Clc1ccc(CCN2CCN3CCC[C@H]3C2)cc1Cl CHEMBL74729 Ki 5.4 nM
CN(CCc1cccc(F)c1)CCN1CCCC1 CHEMBL152478 Ki 5.4 nM
Oc1cccc2c1CCCC2CCCN1CCN(C2CCCCC2)CC1 CHEMBL74723 Ki 5.4 nM
CC1CCN(CCCc2ccc(C(C)(C)C)cc2)CC1 CHEMBL4101014 Ki 5.4 nM
CC1(C)OCC(CN2CCN(Cc3ccccc3)CC2)O1 CHEMBL4639948 Ki 5.4 nM
c1ccc2c(c1)CCCC21CCN(CC2CCCO2)CC1 CHEMBL1743991 Log IC50 5.495 nM
Cc1ccc2c(c1)CCCC21CCN(Cc2ccccc2)CC1 CHEMBL1743998 Log IC50 5.495 nM
CN(C)C1Cc2ccccc2C(C)(c2ccccc2)C1 CHEMBL320190 Log IC50 5.495 nM
COc1ccc(CN2CCC[C@H](OCc3ccc(C)cc3)C2)cc1F CHEMBL5187429 pKi 5.495 nM
Cc1cc(OCCN2CCCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170227 Ki 5.5 nM
O=C(Cc1cccc(F)c1)NC1CCN(Cc2ccc(F)cc2)CC1 CHEMBL136451 Ki 5.51 nM
COc1cccc2c1CCC[C@@H]2CCCN1CCN(C2CCCCC2)CC1 CHEMBL73854 Ki 5.54 nM
Cc1ccc(C(=O)C(C)CN2CCCCC2)cc1 CHEMBL1076211 Ki 5.587 nM
COc1c(C(=O)NC2CCN(Cc3ccccc3)CC2)cc(Br)c2ccccc12 CHEMBL51959 Ki 5.6 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN(C)c1ccccc1 CHEMBL289948 Ki 5.6 nM
OCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL358579 Ki 5.66 nM
CC(=O)Nc1ccc2c(c1)C1(C)CCN(Cc3ccccc3)C(C2)C1C CHEMBL419343 Ki 5.68 nM
CCCN(CCC)C(CC)Cc1ccc(OC)c(OCCc2ccccc2)c1 CHEMBL128717 IC50 5.7 nM
CCc1cccc(NC(=N)Nc2cc(CC)cc(CC)c2Br)c1 CHEMBL553034 IC50 5.7 nM
C[C@H](Cc1ccccc1)NCCCc1ccc2ccccc2c1 CHEMBL19878 Ki 5.7 nM
O=c1sc2cc(Br)ccc2n1CCCN1Cc2ccccc2C1 CHEMBL3409387 Ki 5.7 nM
COc1c(C(=O)CCC2CCN(Cc3ccccc3)CC2)cc(Cl)c2[nH]ccc12 CHEMBL4526050 Ki 5.7 nM
C[C@H]1[C@@H]2CCN(Cc3ccccc3)[C@H]1Cc1ccccc12 CHEMBL143585 Ki 5.74 nM
N=C(NCCCCCN1CCCC1)NCC1CCCCCC1 CHEMBL77925 Log Ki 5.754 nM
CNCCN(C)CCc1ccc(Cl)c(Cl)c1 CHEMBL142406 Ki 5.78 nM
O=C(Cc1c(F)cccc1F)NC1CCN(Cc2ccccc2)CC1 CHEMBL78059 Ki 5.8 nM
COc1c(C(=O)N[C@H]2CCN(C3CCCCC3)C2)cc(Br)c2ccccc12 CHEMBL54865 Ki 5.8 nM
COc1cccc(/C=C2/C(=O)CC3(c4cccc(O)c4)CCN(C)C2C3)c1 CHEMBL145296 Ki 5.8 nM
C[C@H](Cc1ccccc1)N(C)CCc1ccccc1 CHEMBL436542 Ki 5.8 nM
CN(CCCNS(=O)(=O)c1ccc(Cl)cc1)Cc1ccccc1 CHEMBL4164330 Ki 5.8 nM
c1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 CHEMBL162522 Ki 5.81 nM
CCOC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL138102 Ki 5.83 nM
Cc1ccc(C2=CCN(CCCCc3ccncc3)CC2)cc1 CHEMBL97285 Ki 5.86 nM
Cc1ccc(CN2CCC3(CCc4ccccc43)CC2)cc1 CHEMBL1744006 Log IC50 5.888 nM
COc1c(C(=O)N[C@@H]2CCN(Cc3ccccc3)C2)cc(Br)c2ccccc12 CHEMBL298875 Ki 5.9 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCNc1ccccc1 CHEMBL287794 Ki 5.9 nM
C/C(=N\C12CC3CC(CC(C3)C1)C2)Nc1ccccc1C CHEMBL542638 IC50 6.0 nM
CN(CCc1ccc(Cl)c(Cl)c1)[C@@H]1CCCC[C@@H]1N1CCCC1 CHEMBL316988 Ki 6.0 nM
CCCCN1CC[C@@]2(C)c3cc(O)ccc3CC1[C@H]2C CHEMBL326571 Ki 6.0 nM
CC(Cc1cccc(Br)c1)NCCCc1ccccc1 CHEMBL281619 Ki 6.0 nM
Cc1ccccc1/N=C(\N)NC1CC2CCC1C2 CHEMBL81773 IC50 6.0 nM
Cc1ccccc1/N=C(\N)NC1C2CC3CC(C2)CC1C3 CHEMBL81461 IC50 6.0 nM
O=C(C#Cc1ccccc1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 CHEMBL112170 Ki 6.0 nM
O=C1CC2(CCN(CCc3ccccc3)CC2)OC=C1c1ccc(F)cc1 CHEMBL543822 Ki 6.0 nM
O=C1C=C(c2ccc(F)cc2)OC12CCN(CCc1ccccc1)CC2 CHEMBL553784 Ki 6.0 nM
CN(CCc1ccc(F)cc1)CCN1CCCC1 CHEMBL153758 Ki 6.0 nM
CCCN1CCC[C@H](c2cccc(O)c2)C1 CHEMBL7393 Ki 6.0 nM
N=C(NCCSC(c1ccccc1)c1ccccc1)NCCc1c[nH]cn1 CHEMBL365722 Ki 6.0 nM
O[C@H]1C[C@@H]2CN(CC3CCCCC3)[C@H]1CN2Cc1cccc2ccccc12 CHEMBL3817940 Ki 6.0 nM
CC1OC2(CCN(CCc3ccccc3)CC2)CN(c2ccccc2)C1=O CHEMBL4541206 Ki 6.0 nM
CCC1OC2(CCN(CCc3ccccc3)CC2)CN(c2ccccc2)C1=O CHEMBL4515812 Ki 6.0 nM
Cc1cc(COCCN2CCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL4792105 Ki 6.0 nM
CCCCCN1C[C@@H]2[C@@H](C1)OCc1c(-c3ccccc3)nnn12 CHEMBL5189328 Ki 6.0 nM
O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL4080696 Ki 6.0 nM
CN(C)C1Cc2cc(O)c(O)cc2C(c2ccccc2)C1 CHEMBL105645 Log IC50 6.166 nM
COc1c(C(=O)N[C@@H]2CCN(C3C4CCCC3CCC4)C2)cc(Br)c2ccccc12 CHEMBL301302 Ki 6.2 nM
COc1c(C(=O)N[C@@H]2CCN(C3[C@H]4C[C@@H]5C[C@@H](C[C@H]3C5)C4)C2)cc(Br)c2ccccc12 CHEMBL51754 Ki 6.2 nM
CCCc1ccc(CC(C)NCCCc2ccccc2)cc1 CHEMBL53253 Ki 6.2 nM
N=C(Nc1ccccc1I)NC12CC3CC(CC(C3)C1)C2 CHEMBL55970 IC50 6.2 nM
CN(CCCN1CCc2c([nH]c3ccccc23)C1)Cc1ccccc1 CHEMBL3360553 Ki 6.2 nM
O=C(Cc1ccccc1)NC1CCN(Cc2ccc(F)c(F)c2)CC1 CHEMBL344023 Ki 6.3 nM
CC(Cc1ccc2ccccc2c1)NCCCc1ccccc1 CHEMBL19541 Ki 6.3 nM
CN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 CHEMBL73824 Ki 6.3 nM
Clc1ccc(CCN2CCOCC2)cc1Cl CHEMBL2338780 Ki 6.3 nM
CN(C)CC1CCOC1(c1ccccc1)c1ccccc1 CHEMBL4297224 Ki 6.3 nM
CCCCN1CC[C@H]2c3ccccc3CC[C@H]2C1 CHEMBL544282 Log IC50 6.31 nM
c1csc(CN2CCC3(CCCc4ccccc43)CC2)c1 CHEMBL1743994 Log IC50 6.31 nM
CN(CCc1cccc([N+](=O)[O-])c1)CCN1CCCC1 CHEMBL118405 Ki 6.4 nM
CN(CCCn1c(=O)oc2ccc(Cl)cc21)Cc1ccccc1 CHEMBL3409375 Ki 6.4 nM
O[C@H]1CC[C@H]2CN(CC3CCCCC3)[C@@H]1CN2Cc1ccccc1 CHEMBL3819463 Ki 6.4 nM
N=C(NCCCCCN1CCCC1)NCC12CC3CC(CC(C3)C1)C2 CHEMBL76256 Log Ki 6.457 nM
Cc1ccc(CN2CCC[C@H](OCc3ccc(F)c(C)c3)C2)cc1 CHEMBL5189986 pKi 6.457 nM
O=C(Cc1ccc(Cl)cc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL413057 Ki 6.46 nM
CN(CCNC(=O)c1cccc(Cl)c1Cl)Cc1ccccc1 CHEMBL4166747 Ki 6.5 nM
CN(CCCC(=O)Nc1ccc(Cl)cc1)Cc1ccccc1 CHEMBL4173950 Ki 6.5 nM
O=C(Cc1ccccc1)NC1CCN(Cc2ccc(F)cc2)CC1 CHEMBL341957 Ki 6.59 nM
C[C@@H](Cc1ccccc1)NCCCCc1ccccc1 CHEMBL20976 Ki 6.6 nM
O=C1[C@H]2Cc3ccccc3CN2C(=O)N1CCN1CCCCC1 CHEMBL195304 IC50 6.6 nM
c1coc(CN2CC[C@H]3c4ccccc4CC[C@H]3C2)c1 CHEMBL545689 Log IC50 6.607 nM
C=CCCN1CCC2(CCCc3ccccc32)CC1 CHEMBL1743996 Log IC50 6.607 nM
COC1Cc2ccccc2C2(CCN(CCc3ccccc3)CC2)O1 CHEMBL141743 Ki 6.64 nM
O=S(=O)(NCCN1CCCC1)c1ccc(Br)cc1 CHEMBL81360 Ki 6.65 nM
c1ccc(CCCN2CCN(c3ccccc3)CC2)cc1 CHEMBL111896 Ki 6.7 nM
CCCN1CCN(c2ccc(C3CCCCN3C(=O)OCc3ccccc3)cc2)CC1 CHEMBL5206383 Ki 6.7 nM
O=C(Cc1ccccc1)NC1CCN(Cc2cccc(I)c2)CC1 CHEMBL137675 Ki 6.75 nM
Clc1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1743995 Log IC50 6.761 nM
c1ccc(CN2CCC3(CCCCc4ccccc43)CC2)cc1 CHEMBL1744011 Log IC50 6.761 nM
Clc1ccc2c(c1)CCCC21CCN(Cc2ccccc2)CC1 CHEMBL1744007 Log IC50 6.761 nM
N=C(NCCCCCN1CCCCCC1)NCC12CC3CC(CC(C3)C1)C2 CHEMBL274490 Log Ki 6.761 nM
CNCCCCCC1CCCCC1 CHEMBL278525 Ki 6.8 nM
OCC[C@H]1CN(CC2CCCCC2)CCN1Cc1ccc2ccccc2c1 CHEMBL3233532 Ki 6.8 nM
Brc1cccc(CNC2C3C4CC5C6C4C2C6C2(OCCO2)C53)c1 CHEMBL541347 Ki 6.9 nM
Cc1cc(OCCCCN2CCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170222 Ki 6.9 nM
COC1Cc2ccccc2[C@]2(CC[C@@H](N(C)CC3CCCCC3)CC2)O1 CHEMBL4576927 Ki 6.9 nM
COc1ccc(N2C[C@H](CN3CCC(O)(c4ccccc4)CC3)OC2=O)cc1 CHEMBL417357 Ki 7.0 nM
C(#Cc1ccccc1)COCCC1CCN(CCc2ccccc2)CC1 CHEMBL78067 Ki 7.0 nM
C(=C/c1ccccc1)\COCC1CCN(Cc2ccccc2)CC1 CHEMBL76849 Ki 7.0 nM
COc1cccc2c1CCCC2CCCN1CCN(Cc2ccccc2)CC1 CHEMBL54020 Ki 7.0 nM
COc1ccc2c(c1)CCC(C1CCN(Cc3ccccc3)CC1)C2=O CHEMBL123014 Ki 7.0 nM
O=C(CCN1CCC(c2ccccc2)CC1)c1ccccc1 CHEMBL340401 IC50 7.0 nM
C(=C/c1ccccc1)\CN(C/C=C/c1ccccc1)C1CCN(Cc2ccccc2)CC1 CHEMBL320801 Ki 7.0 nM
O=C1CC2(CCN(CCc3ccccc3)CC2)OC=C1c1cccs1 CHEMBL543823 Ki 7.0 nM
COc1ccc(/N=C(\N)NC23CC4CC(CC(C4)C2)C3)c(C)c1 CHEMBL55873 IC50 7.0 nM
COc1cccc(NC(=N)NC23CC4CC(CC(C4)C2)C3)c1 CHEMBL54407 IC50 7.0 nM
Cn1ncc2c1CCCC2CCN1CCC(c2ccccc2)CC1 CHEMBL2436338 Ki 7.0 nM
CCCNC(=S)Nc1ncnc2c1cnn2CCN1CCCCCC1 CHEMBL4284119 Ki 7.0 nM
c1csc(CN2CC[C@H]3c4ccccc4CC[C@H]3C2)c1 CHEMBL554388 Log IC50 7.079 nM
Fc1ccc(CN2CCCC3(CCN(Cc4cc5ccc(Cl)cc5[nH]4)C3)C2)cc1F CHEMBL5289958 pKi 7.079 nM
Cc1cc(OCCCCN2CCCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170223 Ki 7.1 nM
CN(CCCN1C(=O)[C@H]2Cc3ccccc3CN2C1=O)Cc1ccccc1 CHEMBL1089752 Ki 7.1 nM
OCC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL434067 Ki 7.16 nM
CC1C2Cc3ccc(Cl)cc3C1(C)CCN2Cc1ccccc1 CHEMBL276078 Ki 7.16 nM
O=C(Cc1ccsc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL138249 Ki 7.2 nM
CC(=O)C1CCN(CCOc2ccn(-c3ccc(Cl)c(Cl)c3)n2)CC1 CHEMBL2170213 Ki 7.2 nM
CCCN(CCCc1ccccc1)CCc1ccc(N=[N+]=[N-])c([125I])c1 CHEMBL3103203 Kd 7.2 nM
CN(CCCN1CCc2c([nH]c3ccccc23)C1)CCc1ccccc1 CHEMBL3360561 Ki 7.2 nM
O[C@@H]1C[C@H]2CN(CC3CCCCC3)[C@@H]1CN2Cc1cccc2ccccc12 CHEMBL3818112 Ki 7.2 nM
Fc1ccc(SCCCN2CCCN(c3ccc(Cl)cn3)CC2)cc1 CHEMBL4577233 Ki 7.2 nM
O=C(Cc1ccccc1)NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 CHEMBL139156 Ki 7.24 nM
OCCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL357179 Ki 7.27 nM
O=C(Cc1c(Cl)cccc1Cl)NC1CCN(Cc2ccccc2)CC1 CHEMBL77352 Ki 7.28 nM
CCCCc1ccc(C(=O)NCCCN(C)Cc2ccccc2)cc1 CHEMBL4161016 Ki 7.3 nM
COC1Cc2ccccc2[C@]2(CC[C@H](N(C)CC3CCCCC3)CC2)O1 CHEMBL4562252 Ki 7.3 nM
O=C(Cc1ccc2c(c1)OCO2)NC1CCN(Cc2ccccc2)CC1 CHEMBL80397 Ki 7.32 nM
OC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL138533 Ki 7.33 nM
CCc1cccc(NC(=N)Nc2cc(CC)cc(CC)c2F)c1 CHEMBL552829 IC50 7.4 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN1CCCC1 CHEMBL43398 Ki 7.4 nM
CN(CCc1ccccc1)CCN1CCCC1 CHEMBL409984 Ki 7.4 nM
FC(F)(F)c1cccc(N2CCN(CCc3ccccc3)CC2)c1 CHEMBL113293 Ki 7.5 nM
OCC[C@@H]1CN(CC2CCCCC2)CCN1Cc1cccc2ccccc12 CHEMBL3233531 Ki 7.5 nM
Cn1nc(CN2CCCC2)nc1-c1ccc(C(C)(C)C)cc1 CHEMBL4799971 Ki 7.5 nM
CCN1CCN(Cc2cccc3ccccc23)[C@H](CCO)C1 CHEMBL5291247 Ki 7.5 nM
CCCCN1CCC2=C(CCc3ccccc32)C1 CHEMBL541299 Log IC50 7.586 nM
Clc1ccc(CN2CCN(Cc3ccccc3)CC2)c(Cl)c1 CHEMBL422020 Ki 7.6 nM
O=C(Cc1cccc([N+](=O)[O-])c1)N1CCN(CCCc2ccccc2)CC1 CHEMBL148377 Ki 7.6 nM
O=C(Cc1cc(F)cc(F)c1)NC1CCN(Cc2ccccc2)CC1 CHEMBL312254 Ki 7.63 nM
CN(CCc1ccccc1[N+](=O)[O-])CCN1CCCC1 CHEMBL324513 Ki 7.7 nM
N=C(NCCCCCN1CCCCC1)NCC12CC3CC(CC(C3)C1)C2 CHEMBL78272 Log Ki 7.762 nM
c1ccc(CCCNC2CCc3ccccc3CC2)cc1 CHEMBL296601 Ki 7.9 nM
O=C(Cc1ccccc1[N+](=O)[O-])N1CCN(CCCc2ccccc2)CC1 CHEMBL144469 Ki 7.9 nM
C[C@@]12COc3cc(OCc4ccccc4)ccc3[C@@H]1CCN2 CHEMBL4589450 pKi 7.943 nM
O=C(OCc1ccccc1)N1CCCCC1c1cccc(N2CCN(C3CCCC3)CC2)c1 CHEMBL5177703 pKi 7.943 nM
Cn1c(=O)sc2cc(CCN3CCN(Cc4ccc(Cl)cc4Cl)CC3)ccc21 CHEMBL280063 Ki 8.0 nM
CN(CCCN(C)Cc1ccc(Cl)c(Cl)c1)CCN1CCCC1 CHEMBL107870 Ki 8.0 nM
CCCNC(CC)Cc1ccc(OC)c(OCCc2ccccc2)c1 CHEMBL127899 IC50 8.0 nM
C/C=C/CN1CCC(COC/C=C/c2ccccc2)CC1 CHEMBL76475 Ki 8.0 nM
C(=C/c1ccccc1)\COCC1CCN(Cc2cccc3ccccc23)CC1 CHEMBL309015 Ki 8.0 nM
CCc1cccc(NC(=N)Nc2cc(CC)cc(CC)c2)c1 CHEMBL552831 IC50 8.0 nM
Cc1ccc(CN2CCC(C3CCc4ccccc4C3=O)CC2)cc1 CHEMBL124234 Ki 8.0 nM
O=C(CCN1CC=C(c2ccccc2)CC1)c1ccccc1 CHEMBL130357 IC50 8.0 nM
CCc1cccc(NC(=N)Nc2cccc(CC)c2)c1 CHEMBL78777 IC50 8.0 nM
Cc1ccccc1/N=C(\N)NC12CC3CC(CC(C3)C1)C2 CHEMBL81835 IC50 8.0 nM
N=C(NC1CCCCC1)NC12CC3CC(CC(C3)C1)C2 CHEMBL543597 IC50 8.0 nM
O=C(C#Cc1ccccc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL113449 Ki 8.0 nM
N=C(Nc1ccccc1F)NC12CC3CC(CC(C3)C1)C2 CHEMBL293059 IC50 8.0 nM
N=C(Nc1cccc(I)c1)NC12CC3CC(CC(C3)C1)C2 CHEMBL55769 IC50 8.0 nM
CCN(CC)CCOc1ccc(/C(=C(/Cl)c2ccccc2)c2ccccc2)cc1 CHEMBL954 Ki 8.0 nM
CCN(CC)CCOc1ccc(C(O)(Cc2ccc(Cl)cc2)c2ccc(C)cc2)cc1 CHEMBL187709 Ki 8.0 nM
c1ccc2c(c1)CN(CCCN1CCc3c([nH]c4ccccc34)C1)C2 CHEMBL3360569 Ki 8.0 nM
CC1OC2(CCN(CCc3ccccc3)CC2)CN(c2ccccc2Cl)C1=O CHEMBL4452042 Ki 8.0 nM
CC1OC2(CCN(CCc3ccccc3)CC2)CN(c2cccc(C(F)(F)F)n2)C1=O CHEMBL4538620 Ki 8.0 nM
CC1OC2(CCN(CCc3ccccc3F)CC2)CN(c2ccccc2)C1=O CHEMBL4536259 Ki 8.0 nM
CC1OC2(CCN(CCc3cccc(F)c3)CC2)CN(c2ccccc2)C1=O CHEMBL4534193 Ki 8.0 nM
C=C1CCN2Cc3ccc(OC)cc3[C@H]3CCCC[C@]32C1 CHEMBL4777306 Ki 8.0 nM
CCC(=O)N(Cc1ccccc1)CC1(N2CCN(Cc3ccccc3)CC2)CC1 CHEMBL5094913 Ki 8.0 nM
CCC(=O)N(CC1(N2CCN(Cc3ccccc3)CC2)CC1)c1cccc(C(F)(F)F)n1 CHEMBL5081133 Ki 8.0 nM
Fc1ccc(COC2CCN(Cc3cc4ccc(Cl)cc4[nH]3)CC2)cc1F CHEMBL5170670 Ki 8.1 nM
COc1ccc(CCN2CCN(CCc3ccc(OC)cc3)CC2)cc1 CHEMBL146411 Ki 8.2 nM
COCCN(C)CCCCOc1ccn(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL2170206 Ki 8.2 nM
Clc1ccc(-n2ccc(OCCN3CCOCC3)n2)cc1Cl CHEMBL2170237 Ki 8.2 nM
O=C(Cc1ccccc1)NC1CCN(Cc2cccc(F)c2)CC1 CHEMBL139629 Ki 8.22 nM
CC(Cc1ccc(I)cc1)NCCCc1ccccc1 CHEMBL293952 Ki 8.3 nM
Fc1ccc(COC2CCN(Cc3ccc4[nH]cnc4c3)CC2)cc1F CHEMBL5170381 Ki 8.3 nM
O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1CCCCN1CCC(c2ccccc2)CC1 CHEMBL303408 Ki 8.4 nM
Cc1cc(OCCN2CCC(C)CC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170229 Ki 8.4 nM
c1ccc(C2c3[nH]c4ccccc4c3CCN2CCCN2Cc3ccccc3C2)cc1 CHEMBL3360570 Ki 8.4 nM
CC1CN(CCCc2ccc(C(C)(C)C)cc2)CC(C)O1 CHEMBL4098546 Ki 8.4 nM
O[C@H](Cc1ccc(Br)cc1)CN1CCC2(CCc3ccccc32)CC1 CHEMBL340185 Ki 8.5 nM
C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1 CHEMBL143407 IC50 8.5 nM
C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1CCCc1ccccc1 CHEMBL348432 IC50 8.5 nM
Cc1cc(OCCNC2CCCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170235 Ki 8.5 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL726 Ki 8.575 nM
C[C@H](Cc1ccccc1)NCCCc1cccc2ccccc12 CHEMBL277466 Ki 8.6 nM
C[C@@H]1CN(CCOC(c2ccccc2)c2ccccc2)[C@@H](C)CN1CCCc1ccccc1 CHEMBL140054 IC50 8.6 nM
CC1CCN(CCOc2ccn(-c3ccc(Cl)c(Cl)c3)n2)CC1 CHEMBL2170212 Ki 8.6 nM
CN(C(=O)Cc1ccc2ccccc2c1)[C@H]1CCCC[C@H]1N1CCCC1 CHEMBL607155 Ki 8.66 nM
O=C(Cc1ccccc1C(F)(F)F)NC1CCN(Cc2ccccc2)CC1 CHEMBL306955 Ki 8.7 nM
COc1ccc(CN2CCC[C@H](OCc3ccccc3C)C2)cc1F CHEMBL5199649 Ki 8.7 nM
O=[N+]([O-])c1ccc(CN2CC[C@H]3c4ccccc4CC[C@H]3C2)cc1 CHEMBL544747 Log IC50 8.71 nM
COc1ccc(CN2CCC[C@@H](OCc3ccc(F)c(C)c3)C2)cc1F CHEMBL5184607 pKi 8.71 nM
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 CHEMBL83 Ki 8.714 nM
CC(Cc1ccc(Br)cc1)NCCCc1ccccc1 CHEMBL19802 Ki 8.8 nM
C=CCN(C)C1Cc2ccccc2C(c2ccccc2)C1 CHEMBL540038 IC50 8.9 nM
CN(CCN1CCCC1)Cc1cccc(Br)c1 CHEMBL152618 Ki 8.9 nM
Clc1ccc(-n2ccc(OCCN3CCCCCC3)n2)cc1Cl CHEMBL2170211 Ki 8.9 nM
CCOC(=O)C1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21 CHEMBL148009 Ki 8.95 nM
C/C(=N\C1CCCCC1)Nc1ccccc1C CHEMBL544054 IC50 9.0 nM
C/C(=N\C1CC2CCC1C2)Nc1ccccc1C CHEMBL63508 IC50 9.0 nM
Cn1c(=O)sc2cc(CCCCN3CCN(Cc4ccc(Cl)cc4Cl)CC3)ccc21 CHEMBL15637 Ki 9.0 nM
CCCCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC CHEMBL339638 IC50 9.0 nM
CN(C)[C@]1(C)Cc2ccccc2[C@@H](c2ccccc2)C1 CHEMBL2093895 IC50 9.0 nM
O=C1c2ccc(Cl)cc2CCC1C1CCN(CCc2ccccc2)CC1 CHEMBL545058 Ki 9.0 nM
O=C1c2ccc(F)cc2CCC1C1CCN(Cc2ccccc2)CC1 CHEMBL122538 Ki 9.0 nM
CCN(CC)CCC1(C)OC=C(c2ccccc2)C1=O CHEMBL540538 Ki 9.0 nM
N=C(Nc1ccc(F)cc1)NC12CC3CC(CC(C3)C1)C2 CHEMBL292450 IC50 9.0 nM
Clc1ccc(Cn2cc(NCCN3CCCCCC3)nn2)cc1Cl CHEMBL3417066 Ki 9.0 nM
CCNC(=S)Nc1ncnc2c1cnn2CCN1CCCCCC1 CHEMBL4279584 Ki 9.0 nM
O=C(Nc1ncnc2c1cnn2CCN1CCCCCC1)C12CC3CC(CC(C3)C1)C2 CHEMBL4283691 Ki 9.0 nM
CC(C)(C)C(=O)Nc1ncnc2c1cnn2CCN1CCCCCC1 CHEMBL4294268 Ki 9.0 nM
O=C1N(c2ccccc2)CC2(CCN(CCc3ccccc3)CC2)OC12CC2 CHEMBL4438550 Ki 9.0 nM
CC1OC2(CCN(CCc3ccccc3)CC2)CN(c2ccc(C(F)(F)F)nc2)C1=O CHEMBL4560624 Ki 9.0 nM
CC(=O)N1CCN(CCCOCc2cc(C)n(-c3ccc(Cl)c(Cl)c3)n2)CC1 CHEMBL4776009 Ki 9.0 nM
Cc1cc(CCCCN2CCOCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL4795798 Ki 9.0 nM
Fc1ccccc1-c1nnn2c1CO[C@@H]1CN(Cc3ccccc3)C[C@H]12 CHEMBL5197005 Ki 9.0 nM
O=C(Cc1ccccc1)NC1CCN(Cc2ccc(I)cc2)CC1 CHEMBL139735 Ki 9.03 nM
COc1ccc2c(c1)C(CCCN1CCN(C3CCCCC3)CC1)CCC2 CHEMBL75444 Ki 9.04 nM
COc1cccc(S(=O)(=O)N2CCC[C@@H]2CCN2CCC(C)CC2)c1 CHEMBL332701 Ki 9.2 nM
CC(Cc1ccccc1)NCCCCc1ccccc1 CHEMBL12047 Ki 9.3 nM
CC(Cc1cccc2ccccc12)NCCCc1ccccc1 CHEMBL19082 Ki 9.3 nM
CCOC(=O)C1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 CHEMBL358541 Ki 9.33 nM
CN1CC[C@@]2(c3cccc(O)c3)CC(=O)/C(=C/c3ccccc3)[C@@H]1C2 CHEMBL2111684 Ki 9.4 nM
COc1ccc2c(c1)CC(CN1CCC(Cc3ccccc3)CC1)CC2 CHEMBL178680 Ki 9.4 nM
CN(CCCCCCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)Cc1ccccc1 CHEMBL194640 IC50 9.4 nM
Cc1c(OCCN2CCOCC2)nn(-c2ccc(Cl)c(Cl)c2)c1C CHEMBL2170055 Ki 9.4 nM
Cc1cc(OCCN2CCCCCC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170228 Ki 9.4 nM
CCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)N(CCC)CCC CHEMBL341003 IC50 9.5 nM
COc1ccc(CC(C)NCCCc2ccccc2)cc1 CHEMBL53170 Ki 9.5 nM
Clc1ccc(-n2ccc(NCCN3CCCCC3)n2)cc1Cl CHEMBL2170054 Ki 9.5 nM
c1coc(CN2CCC3(CCCc4ccccc43)CC2)c1 CHEMBL1743993 Log IC50 9.55 nM
N=C(NCCCCCN1CCCCCCC1)NCC12CC3CC(CC(C3)C1)C2 CHEMBL76944 Log Ki 9.55 nM
C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN1CCCCC1 CHEMBL41313 Ki 9.6 nM
c1ccc(CCCCNCc2ccccc2)cc1 CHEMBL19628 Ki 9.6 nM
O=C1[C@@H]2Cc3ccccc3CN2C(=O)N1CCCNCc1ccccc1 CHEMBL196988 IC50 9.6 nM
Clc1ccc(-n2ccc(OCCCN3CCCCC3)n2)cc1Cl CHEMBL2170219 Ki 9.6 nM
O=C(Cc1ccc(Cl)cc1Cl)NC1CCN(Cc2ccccc2)CC1 CHEMBL262760 Ki 9.66 nM
COc1ccccc1N1CCN(CCCC2CCCc3ccsc32)CC1 CHEMBL174083 IC50 9.7 nM
O=C(Cc1ccc(C(F)(F)F)cc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL77773 Ki 9.84 nM
COc1cccc2c1CCC(CN1CCC(Cc3ccccc3)CC1)C2 CHEMBL180119 Ki 9.9 nM
CN(CCCCN1C(=O)[C@@H]2Cc3ccccc3CN2C1=O)CCc1ccccc1 CHEMBL194797 IC50 9.9 nM
Cc1cc(OCCN2CCCC2)nn1-c1ccc2ccccc2c1 CHEMBL2170068 Ki 9.9 nM
Cc1cc(OCCCCN2CCN(C)CC2)nn1-c1ccc(Cl)c(Cl)c1 CHEMBL2170071 Ki 9.9 nM
CCN(CC)CCOc1cc(C)n(-c2ccc(Cl)c(Cl)c2)n1 CHEMBL2170234 Ki 9.9 nM
Cn1nc(CN2CCCC2)nc1-c1ccc(C2(C(F)(F)F)CC2)cc1 CHEMBL4796342 Ki 9.9 nM