CC(C)[C@@H]1NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCNC(=O)C(F)(F)F)NC1=O CHEMBL3769432 IC50 1.0 nM
CS(=O)(=O)NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2338810 IC50 1.1 nM
CCNC(=O)c1cccc(C(=O)NCCC2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)c1 CHEMBL2332037 IC50 1.3 nM
CC(C)(C)OC(=O)c1ccc(C(=O)NCCC2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)s1 CHEMBL2332041 IC50 1.8 nM
CCNC(=O)c1ccc(C(=O)NCCC2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)s1 CHEMBL2332039 IC50 2.7 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCNC(=O)C(F)(F)F)NC1=O CHEMBL3779989 IC50 3.2 nM
NC(=O)c1cc2ncnc(N3CCC(CCNC(=O)c4ccc(C(=O)O)s4)CC3)c2s1 CHEMBL2332042 IC50 4.4 nM
CCNC(=O)c1ccc(C(=O)NCCN2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)s1 CHEMBL2332040 IC50 4.8 nM
CC(C)(C)OC(=O)NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332044 IC50 5.4 nM
NC(=O)c1cc2ncnc(N3CCC(CCNC(=O)c4cccs4)CC3)c2s1 CHEMBL2332043 IC50 6.5 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccc(O)cc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4446458 IC50 7.0 nM
CC(C)(C)C(=O)NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332055 IC50 10.0 nM
CCNC(=O)c1cccc(C(=O)NCCN2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)c1 CHEMBL2332038 IC50 10.0 nM
CSCC[C@H](NC(=O)[C@@H]1CCCCNC(=O)CCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N1)C(N)=O CHEMBL3781485 IC50 10.1 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccccc4)cc3)c2)c1 CHEMBL3805001 IC50 13.5 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc4cn[nH]c4c3)c2)c1 CHEMBL3805929 IC50 15.7 nM
CC(C)(C)C(=O)NCCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2338808 IC50 16.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(N4CCOCC4)cc3)c2)c1 CHEMBL3805692 IC50 16.7 nM
CC(C)(C)C(=O)NCCN1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2338809 IC50 17.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-n4cnnc4)cc3)c2)c1 CHEMBL3804834 IC50 19.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccccc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4447813 IC50 19.0 nM
CCCCCCCCCCCCCC(=S)NCCCCC(NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4638983 IC50 20.0 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4438193 IC50 22.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-n4cccc4)nc3)c2)c1 CHEMBL3805063 IC50 22.4 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccccn4)cc3)c2)c1 CHEMBL3805835 IC50 22.7 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccncc4)cc3)c2)c1 CHEMBL3806268 IC50 22.9 nM
CC(=O)NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332045 IC50 23.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc4ccccc4c3)c2)c1 CHEMBL3805112 IC50 23.4 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4cccs4)cc3)c2)c1 CHEMBL3805479 IC50 26.3 nM
CN(C)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805070 IC50 26.7 nM
CC(C)(C)C(=O)NCCC1CCN(c2ccnc3cc(C(N)=O)sc23)CC1 CHEMBL2338816 IC50 28.0 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4129995 IC50 28.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4cccnc4)cc3)c2)c1 CHEMBL3805847 IC50 28.1 nM
CNC(=O)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805072 IC50 28.1 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccco4)nc3)c2)c1 CHEMBL3805639 IC50 28.9 nM
NC(=O)c1cc2ncnc(N3CCN(CCN4CCCC4)CC3)c2s1 CHEMBL2338814 IC50 29.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccccc4)c(F)c3)c2)c1 CHEMBL3805586 IC50 29.3 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4cccnc4)c(F)c3)c2)c1 CHEMBL3805934 IC50 29.7 nM
CC(=S)NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332052 IC50 30.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)C(F)(F)F)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4458848 IC50 31.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cc4ccccc4s3)c2)c1 CHEMBL3804891 IC50 33.1 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-n4cccn4)nc3)c2)c1 CHEMBL3805825 IC50 33.3 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccncc3)c2)c1 CHEMBL3806257 IC50 34.1 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc4cc[nH]c4c3)c2)c1 CHEMBL3805740 IC50 35.4 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccc(N(C)C)cc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4457496 IC50 36.0 nM
CCCCCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(O)c1 CHEMBL4574578 IC50 36.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(F)cc3)c2)c1 CHEMBL3804850 IC50 36.8 nM
C#Cc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805831 IC50 41.5 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(F)c(F)c3)c2)c1 CHEMBL3805426 IC50 41.8 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4cccs4)nc3)c2)c1 CHEMBL3805578 IC50 41.9 nM
Cc1cc(C)nc(SCC(=O)Nc2cccc(COc3ccc(NC(=O)c4cccs4)cc3)c2)n1 CHEMBL4070149 IC50 42.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)/C=C/c3ccncc3)c2)c1 CHEMBL3805547 IC50 43.6 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-n4cccn4)cc3)c2)c1 CHEMBL3805630 IC50 44.7 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4nccs4)cc3)c2)c1 CHEMBL3804908 IC50 46.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccncc4)c(F)c3)c2)c1 CHEMBL3805492 IC50 46.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccccc4)nc3)c2)c1 CHEMBL3805694 IC50 46.8 nM
NC(=O)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805304 IC50 47.8 nM
NC(=O)c1cncc(Oc2cccc3c(NC(=O)c4ccccc4)cccc23)c1 CHEMBL3343652 IC50 48.3 nM
CC(=O)Nc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805427 IC50 48.6 nM
CCCCCCCCCCCCCC(=S)NCCCCC(NC(=O)Oc1ccccc1)C(=O)Nc1ccccc1 CHEMBL3940508 IC50 50.0 nM
CS(=O)(=O)NCCN1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2338811 IC50 53.0 nM
CSCC[C@H](NC(=O)[C@@H]1CCCCNC(=O)CNC(=O)CCCCC(=O)NCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N1)C(N)=O CHEMBL3781226 IC50 53.1 nM
CSCC[C@H](NC(=O)[C@@H]1CCCCNC(=O)CNC(=O)CCC(=O)NCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N1)C(N)=O CHEMBL3780405 IC50 58.9 nM
CCCCCCCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(O)c1 CHEMBL4456262 IC50 60.0 nM
CCCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4437455 IC50 61.0 nM
CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccccc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O CHEMBL4529328 IC50 63.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cc4ccccc4o3)c2)c1 CHEMBL3805130 IC50 64.7 nM
NC(=O)c1cc2ncnc(N3CCC(CCN4CCCC4)CC3)c2s1 CHEMBL2338813 IC50 67.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccc(N(CC)CC)cc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4461872 IC50 68.0 nM
O=C1CNC(=O)[C@H](CCCCNC(=S)CNC(=O)c2ccccc2Nc2cccc(OCCc3ccccc3)c2)N1 CHEMBL4465620 Ki 68.0 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)CCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)C(=O)Nc1ccccc1 CHEMBL4798823 IC50 69.0 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NS(C)(=O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O CHEMBL5286760 IC50 70.0 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NS(C)(=O)=O)C(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O CHEMBL5274785 IC50 70.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cc4ccccc4[nH]3)c2)c1 CHEMBL3805464 IC50 71.4 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cccc(F)c3)c2)c1 CHEMBL3805650 IC50 75.4 nM
Cc1ccc(C(=O)Nc2cccc3c(Oc4cncc(C(N)=O)c4)cccc23)cc1 CHEMBL3343653 IC50 77.4 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)CCOCCOCCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)C(=O)Nc1ccccc1 CHEMBL4762508 IC50 78.0 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)CCOCCOCNc1cccc2c1C(=O)N(C1CCC(=O)NC1)C2=O)C(=O)Nc1ccccc1 CHEMBL5267372 IC50 78.0 nM
CCCCCCCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4463565 IC50 81.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3c[nH]c4ccccc34)c2)c1 CHEMBL3805778 IC50 83.1 nM
CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)CCOCCOCCOCCOCNc1cccc2c1C(=O)N(C1CCC(=O)NC1)C2=O)C(=O)NC CHEMBL5273182 IC50 93.0 nM
CC(C)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805224 IC50 94.7 nM
NC(=O)C1CCCc2c1[nH]c1ccc(Cl)cc21 CHEMBL420311 IC50 98.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(N4CCCC4)cc3)c2)c1 CHEMBL3805035 IC50 98.2 nM
COC(=O)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805267 IC50 102.0 nM
CCNc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805107 IC50 104.0 nM
Cc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1[N+](=O)[O-] CHEMBL3805478 IC50 107.0 nM
NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332046 IC50 110.0 nM
O=C(O)CCNC(=S)NCCCC[C@H](NS(=O)(=O)c1cccc(F)c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC1CCC1 CHEMBL4636862 IC50 110.0 nM
Cc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3806092 IC50 111.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(N4CCNCC4)cc3)c2)c1 CHEMBL3805538 IC50 112.0 nM
CC(C)(C)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3806033 IC50 113.0 nM
COCCn1cc(COc2cccc(Cc3cnc(NC(=O)CSc4nc(C)cc(C)n4)s3)c2)nn1 CHEMBL4227437 IC50 118.0 nM
CCCCCCC(=S)NCCCCC(NC(=O)Oc1ccccc1)C(=O)Nc1ccccc1 CHEMBL3972352 IC50 120.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccccc2)cc1)NC(=O)[C@@H](NC(C)=O)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O CHEMBL4553811 IC50 120.0 nM
CCCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(O)c1 CHEMBL4466240 IC50 120.0 nM
Cc1c(C(N)=O)sc2c(N3CCC(CCNC(=O)C(C)(C)C)CC3)ncnc12 CHEMBL2338818 IC50 130.0 nM
CC(=S)NCCN1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332053 IC50 130.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(C4CCCCC4)cc3)c2)c1 CHEMBL3805306 IC50 133.0 nM
CSCC[C@H](NC(=O)[C@@H]1CCCCNC(=O)CCCCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N1)C(N)=O CHEMBL3780552 IC50 134.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(OCc4ccccc4)cc3)c2)c1 CHEMBL3806073 IC50 138.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccccc34)s2)n1 CHEMBL3770903 IC50 140.0 nM
CSCC[C@H](NC(=O)[C@@H]1CCCCNC(=O)CNC(=O)CCCCCCC(=O)NCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N1)C(N)=O CHEMBL3781397 IC50 143.6 nM
CC(C)(C)C(=O)NCCC1CCN(c2ncnc3cc(C(N)=O)oc23)CC1 CHEMBL2338815 IC50 150.0 nM
CCCCCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4437014 IC50 150.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(CCCCC(=O)NCc5ccc(C(=O)NO)cc5)nn4)c3)s2)n1 CHEMBL5410652 IC50 150.0 nM
CCc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3806238 IC50 151.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)/C=C/c3ccccc3)c2)c1 CHEMBL3804923 IC50 156.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)/C=C/c3cccnc3)c2)c1 CHEMBL3805890 IC50 157.0 nM
O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1 CHEMBL257991 EC50 160.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(Cc5ccccc5)nn4)c3)s2)n1 CHEMBL4228286 IC50 160.0 nM
CCCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4552464 IC50 160.0 nM
CC(=O)NCCN1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332051 IC50 170.0 nM
COc1ccc2ccccc2c1Cn1cnc2sc3c(c2c1=O)CCC(NCc1cccnc1)C3 CHEMBL3769975 IC50 170.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccnnc3)c2)c1 CHEMBL3804859 IC50 171.0 nM
CCCCCCCCCCC[C@]1(CO)CCCC(=O)O[C@](CO)(CCCCCCCCCCC)CCCC(=O)O1 CHEMBL3347530 IC50 176.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccc(Cl)cc34)s2)n1 CHEMBL3770049 IC50 180.0 nM
CCCC[C@@H]1NC(=O)CCCCCCC(=O)NC[C@@H](C(N)=O)NC(=O)[C@H](CCCCNC(C)=S)NC1=O CHEMBL3962289 IC50 180.0 nM
C=CCNC(=S)N/N=C/c1ccc(OC)c(Cn2cc([N+](=O)[O-])cn2)c1 CHEMBL5273854 IC50 180.0 nM
C[C@H](NC(=O)[C@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccc(O)cc2)cc1)NC(=O)OCc1ccccc1)C(N)=O CHEMBL4457681 IC50 190.0 nM
C[C@H](NC(=O)[C@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccc(OCc3ccccc3)cc2)cc1)NC(=O)OCc1ccccc1)C(N)=O CHEMBL4465910 IC50 190.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cccnc3)c2)c1 CHEMBL3806063 IC50 193.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(Oc4ccccc4)cc3)c2)c1 CHEMBL3804901 IC50 196.0 nM
CCCCCCCNC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4288567 IC50 200.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccc(Br)cc34)s2)n1 CHEMBL3771286 IC50 210.0 nM
CNc1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805574 IC50 216.0 nM
NC(=O)c1cc2ncnc(N3CCC(CN4CCCC4)CC3)c2s1 CHEMBL2338812 IC50 220.0 nM
CCCC[C@@H]1NC(=O)CCCCCCC(=O)NCCC[C@@H](C(N)=O)NC(=O)[C@H](CCCCNC(C)=S)NC1=O CHEMBL3917969 IC50 220.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cccs3)c2)c1 CHEMBL3806225 IC50 235.0 nM
CCCC[C@@H]1NC(=O)CCCCCCC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](CCCCNC(C)=S)NC1=O CHEMBL3889954 IC50 240.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(CCCCNC(=O)COc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)nn4)c3)s2)n1 CHEMBL4225467 IC50 250.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-n4ccnc4)cc3)c2)c1 CHEMBL3805950 IC50 251.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(N4CCCCC4)cc3)c2)c1 CHEMBL3805632 IC50 251.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccccc3)c2)c1 CHEMBL3804871 IC50 252.0 nM
CSCC[C@@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@@H]2Cc3ccc(cc3)OCCCC(=O)N[C@@H](Cc3c[nH]cn3)C(=O)N2)Cc2ccc(cc2)OCCCCCNC1=O CHEMBL4643590 IC50 253.0 nM
Cc1cc(C)nc(S[C@@H](C)C(=O)Nc2ncc(Cc3cccc4ccccc34)s2)n1 CHEMBL3769991 IC50 260.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(F)cc3F)c2)c1 CHEMBL3805728 IC50 277.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccccc3F)c2)c1 CHEMBL3804896 IC50 288.0 nM
CC(C)(C)C(=O)NCCC1CCN(c2nccc3cc(C(N)=O)sc23)CC1 CHEMBL2338817 IC50 300.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(/N=N/c2ccc(N(C)C)cc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4449389 IC50 300.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3c(C)ccc4ccccc34)s2)n1 CHEMBL3770797 IC50 310.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCCC5SCC6NC(=O)NC65)nn4)c3)s2)n1 CHEMBL4225505 IC50 310.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3csc4ccccc34)c2)c1 CHEMBL3805277 IC50 313.0 nM
CCC(Sc1nc(C)cc(C)n1)C(=O)Nc1ncc(Cc2cccc3ccc(Cl)cc23)s1 CHEMBL3771296 IC50 320.0 nM
CCCCN(Cc1ccc(C(=O)NO)cc1)C(=O)CCCCn1cc(COc2cccc(Cc3cnc(NC(=O)CSc4nc(C)cc(C)n4)s3)c2)nn1 CHEMBL5412573 IC50 320.0 nM
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(N)=O CHEMBL3781645 IC50 332.0 nM
CCN(CC)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805448 IC50 366.0 nM
C[C@H](NC(=O)[C@H](CCCCNC(=O)CNC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2)c1)NC(=O)OCc1ccccc1)C(N)=O CHEMBL4471909 IC50 370.0 nM
N#Cc1ccc(CNC2CCc3c(sc4ncn(Cc5cccc6cccnc56)c(=O)c34)C2)cc1 CHEMBL4101347 IC50 390.0 nM
CCCCOc1c(Cl)cc(C(=O)NC(=S)Nc2ccc(NC(=O)CCCCN(C)C)cc2)cc1Cl CHEMBL3931028 IC50 400.0 nM
C[C@H](NC(=O)[C@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccc(OCCc3ccccc3)cc2)cc1)NC(=O)OCc1ccccc1)C(N)=O CHEMBL4464941 IC50 400.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3ccc4ccccc4c3)s2)n1 CHEMBL3770486 IC50 400.0 nM
CCC(C)(C)c1ccc(OCC(O)CN2C[C@H]3C[C@@H](C2)c2cccc(=O)n2C3)c(C(C)(C)CC)c1 CHEMBL5416341 IC50 400.0 nM
CSCC[C@H](NC(=O)[C@@H]1CCCCNC(=O)CCCCCCC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N1)C(N)=O CHEMBL3781129 IC50 404.3 nM
Cc1cc(C)nc(SC(C)C(=O)Nc2ncc(Cc3cccc4ccccc34)s2)n1 CHEMBL3771164 IC50 420.0 nM
CCCC[C@@H]1NC(=O)CCCCCCC(=O)NCC[C@@H](C(N)=O)NC(=O)[C@H](CCCCNC(C)=S)NC1=O CHEMBL3934785 IC50 420.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)C(=O)N[C@@H](CCCCNC(=O)c1ccc(/N=N/c2ccc(N(C)C)cc2)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O CHEMBL4448993 IC50 430.0 nM
NC(=O)c1cncc(Oc2cccc3c(NC(=O)c4cccc([N+](=O)[O-])c4)cccc23)c1 CHEMBL3343654 IC50 434.0 nM
NC(=O)c1cncc(Oc2ccc3c(NC(=O)c4ccccc4)cccc3c2)c1 CHEMBL3343533 IC50 436.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3nc4ccccc4s3)c2)c1 CHEMBL3805790 IC50 437.0 nM
CCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC(C)C CHEMBL4788047 IC50 440.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)/C=C/c3ccccn3)c2)c1 CHEMBL3806211 IC50 450.0 nM
CCC(C)(C)c1ccc(OCC(O)CN2C[C@@H]3C[C@H](C2)c2cccc(=O)n2C3)c(C(C)(C)CC)c1 CHEMBL5272503 IC50 460.0 nM
CC(=O)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805687 IC50 465.0 nM
O=C(CNC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2)c1)NCCCC[C@@H]1NC(=O)CNC1=O CHEMBL4516553 Ki 470.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-n4cccc4)cc3)c2)c1 CHEMBL3805641 IC50 476.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4cc(Cl)ccc34)s2)n1 CHEMBL3770258 IC50 480.0 nM
CC(=S)NCCCC[C@@H]1NC(=O)[C@H](Cc2csc3ccccc23)NC(=O)CCCCCCC(=O)NCCC[C@@H](C(N)=O)NC1=O CHEMBL3964797 IC50 480.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(CCOCCOCCOCCOCCC(=O)Nc5ccc(C(=O)NCc6ccc(C(=O)NO)cc6)cc5)nn4)c3)s2)n1 CHEMBL5407634 IC50 480.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(CCOCCOCCOCCOCCC(=O)Nc5ccc(C(=O)NCCCCCCC(=O)NO)cc5)nn4)c3)s2)n1 CHEMBL5440192 IC50 480.0 nM
Cc1ccc(C(=O)Nc2cccc3cc(Oc4cncc(C(N)=O)c4)ccc23)cc1 CHEMBL3343534 IC50 489.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccncn3)c2)c1 CHEMBL3804932 IC50 500.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)C34CC5CC(CC(C5)C3)C4)c2)c1 CHEMBL3806274 IC50 505.0 nM
CN(C)C(=O)c1ccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)cc1 CHEMBL3805724 IC50 519.0 nM
NC(=O)C1CN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2O1 CHEMBL4868419 IC50 520.0 nM
CCC(Sc1nc(C)cc(C)n1)C(=O)Nc1ncc(Cc2cccc3ccccc23)s1 CHEMBL3771278 IC50 540.0 nM
Cc1cc(C)nc(SC(C)C(=O)Nc2ncc(Cc3cccc4ccc(Cl)cc34)s2)n1 CHEMBL3769999 IC50 540.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)Nc5ccc(C(=O)NCc6ccc(C(=O)NO)cc6)cc5)nn4)c3)s2)n1 CHEMBL5426948 IC50 540.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)C3=CCCCC3)c2)c1 CHEMBL3805709 IC50 546.0 nM
CCCCCCCCCCCCNC(=O)CCCCC[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)CCC(=O)NCC(=O)NCCCC[C@@H](C(N)=O)NC1=O CHEMBL4438364 IC50 550.0 nM
NC(=O)c1cncc(Oc2cccc3c(NC(=O)c4cccnc4)cccc23)c1 CHEMBL3343656 IC50 558.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc(OCc4cn(Cc5ccc(C(=O)NO)cc5)nn4)c3)s2)n1 CHEMBL5400623 IC50 560.0 nM
NC(=O)c1ccccc1Nc1cccc(OCCc2cccc(F)c2)c1 CHEMBL2152621 IC50 570.0 nM
NC(=O)c1ccccc1Nc1cccc(-c2cn(CCC3CCCC3)nn2)c1 CHEMBL3236132 IC50 570.0 nM
NC(=O)c1cncc(OCc2cccc(NC(=O)c3cccc4ccccc34)c2)c1 CHEMBL3805381 IC50 572.0 nM
Cc1cccc(C(=O)Nc2cccc(COc3cncc(C(N)=O)c3)c2)c1 CHEMBL3806001 IC50 580.0 nM
COc1ccc(Cn2cnc3sc4c(c3c2=O)CCC(NCc2c(C)noc2C)C4)c2ccccc12 CHEMBL4088755 IC50 580.0 nM
CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(=O)Cc1ccc(/N=N/c2ccccc2)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(C)=O)[C@@H](C)O)C(N)=O CHEMBL4445565 IC50 580.0 nM
O=C(Nc1cnccc1Br)c1cccc(-c2ccc3ccccc3c2)c1 CHEMBL3358391 IC50 600.0 nM
NC(=O)C1CN(Cc2ccc3nonc3c2)c2ccccc2O1 CHEMBL4861853 IC50 600.0 nM
CCCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 CHEMBL4551157 IC50 640.0 nM
CC(=O)NCCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N[C@@H](CCc1ccccc1)C(N)=O CHEMBL3608444 IC50 650.0 nM
COc1ccc(CNC2CCc3c(sc4ncn(Cc5c(OC)ccc6ccccc56)c(=O)c34)C2)cc1 CHEMBL4091659 IC50 650.0 nM
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@@H]1Cc2ccc(cc2)OCCCC(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N1)C(N)=O CHEMBL4642085 IC50 680.0 nM
COc1cccc(Sc2ccc(NC(=O)CSc3nc(C)cc(C)n3)cc2)c1 CHEMBL4542861 IC50 700.0 nM
COc1ccc(Cn2cnc3sc4c(c3c2=O)CCC(NC2CCCC2)C4)c2ccccc12 CHEMBL4078889 IC50 730.0 nM
CC(C)(C)C(=O)NCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1 CHEMBL2332054 IC50 740.0 nM
Cn1cc(C2=C(c3cn(CCCSC(=N)N)c4ccccc34)C(=O)NC2=O)c2ccccc21 CHEMBL6291 IC50 800.0 nM
Cn1cc(C2=C(c3cn(CCCSC(=N)N)c4ccccc34)C(=O)NC2=O)c2ccccc21 CHEMBL1591531 IC50 800.0 nM
CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCCCNC(C)=S)C(=O)N[C@@H](CCCCNC(C)=O)C(N)=O CHEMBL3609646 IC50 810.0 nM
NC(=O)c1cncc(Oc2ccc3c(NC(=O)c4cccc([N+](=O)[O-])c4)cccc3c2)c1 CHEMBL3343535 IC50 811.0 nM
Cc1cc(C)nc(SCC(=O)Nc2cccc(COc3ccc(NC(=O)c4cnn(C)c4)cc3)c2)n1 CHEMBL4170094 pIC50 812.83 nM
NC(=O)c1ccccc1Nc1cccc(OCCc2ccc(Cl)cc2)c1 CHEMBL2152625 IC50 830.0 nM
Cc1cc(C)nc(SCC(=O)Nc2ccc(Sc3cccc(C(F)(F)F)c3)cc2)n1 CHEMBL4592928 IC50 850.0 nM
Cc1ccc(C(=O)Nc2cccc3cc(Oc4cncc(C(N)=O)c4)ccc23)cc1[N+](=O)[O-] CHEMBL3343532 IC50 869.0 nM
CC(=S)NCCCC[C@@H]1NC(=O)[C@H](Cc2csc3ccccc23)NC(=O)CCCCCCC(=O)NCCCC[C@@H](C(N)=O)NC1=O CHEMBL3925899 IC50 890.0 nM
O=C(Nc1cccnn1)c1cccc(-c2ccc3ccccc3c2)c1 CHEMBL3358386 IC50 900.0 nM
NC(=O)Cc1[nH]c2ccc(Cl)cc2c1Cc1ccccc1 CHEMBL4781198 IC50 930.0 nM
NC(=O)c1cncc(Oc2cccc3c(NC(=O)c4ccncc4)cccc23)c1 CHEMBL3343655 IC50 955.0 nM
O=c1c2c3c(sc2ncn1Cc1cccc2cccnc12)CC(Nc1ccc(F)cc1)CC3 CHEMBL4064852 IC50 970.0 nM
Cc1ccc(C(=O)Nc2cccc3c(Oc4cncc(C(N)=O)c4)cccc23)cc1[N+](=O)[O-] CHEMBL3343651 IC50 978.0 nM
Cc1[nH]c2c(c1C(=O)N(C)Cc1cccc(-c3ccc(C(F)(F)F)cc3)c1)C(=O)CC(C)(C)C2 CHEMBL5282160 IC50 980.0 nM
Cc1ccc([C@H]2CC(=O)Oc3ccc4cc(C)ccc4c32)cc1 CHEMBL270110 IC50 1000.0 nM
CCCCn1c(-c2ccccc2)c(Cc2c(O)ccc3ccccc23)c(=O)[nH]c1=S CHEMBL522620 IC50 1000.0 nM
NC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2)c1 CHEMBL2152613 IC50 1000.0 nM
O=C1CC(c2ccccc2)c2c(ccc3cc(Br)ccc23)O1 CHEMBL270292 IC50 1000.0 nM
CCCCCNC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(O)c1 CHEMBL4436874 IC50 1000.0 nM