CC(C)Cn1c(=O)n(C)c(=O)c2c(SCCCO)c(Cc3cccc4ccccc34)sc21 CHEMBL205526 Ki 0.08 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3C[C@H](O)CO3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL218573 Ki 0.09 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cccc4ccccc34)cc12 CHEMBL380192 pKi 0.0955 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cnc(NCCCCCNC(=O)[C@@H](N)CCC(N)=O)c4ccccc34)cc12 CHEMBL3818777 EC50 0.16 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(S[C@@H]3CC[C@@H](O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL379682 Ki 0.29 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Oc3cccc4ccccc34)sc21 CHEMBL219098 Ki 0.31 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SCCCO)n(Cc3cccc4ccccc34)cc21 CHEMBL85752 Ki 0.33 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SCCCO)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL204887 Ki 0.35 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(S[C@@H]3CC[C@H](O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL205845 Ki 0.42 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3C[C@H](O)CO3)c(Cc3c[nH]c4ncccc34)sc21 CHEMBL384536 Ki 0.43 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3C[C@H](O)CO3)c(Cc3ccnc4ccccc34)sc21 CHEMBL219861 Ki 0.52 nM
O=C(c1c(Cc2cccc3ccc(F)cc23)sc2c1CNCN2)N1CC[C@@H](O)C1 CHEMBL219850 Activity 0.66 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(S[C@@H]3C[C@@H](O)[C@@H](O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL381601 Ki 0.68 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3c[nH]c4ccccc34)sc21 CHEMBL205807 Ki 0.79 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cnc(NCCCCCN)c4ccccc34)cc12 CHEMBL3818311 EC50 0.8 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cc(NCCCCCNC(=O)[C@@H](N)CCC(N)=O)nc4ccccc34)cc12 CHEMBL3817951 EC50 0.8 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(C#CCCCOc4ccc(C[C@H](N)C(=O)O)cc4)c4ccccc34)cc12 CHEMBL3818150 EC50 0.8 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3ccnc4ccc(F)cc34)sc21 CHEMBL218468 Ki 0.81 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(S(=O)(=O)N3CC[C@@H](O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL378405 Ki 1.1 nM
Cc1n[nH]c(C)c1Cc1sc2c(c1C(=O)N1C[C@H](O)CO1)c(=O)n(C)c(=O)n2CC(C)C CHEMBL375166 Ki 1.2 nM
Cc1[nH]nc(C(F)(F)F)c1Cc1sc2c(c1C(=O)N1C[C@](C)(O)CO1)c(=O)n(C)c(=O)n2C(C)C CHEMBL3335793 Kd 1.6 nM
CNc1nc2ccccc2n1Cc1sc2c(c1C(=O)N1C[C@H](O)CO1)c(=O)n(C)c(=O)n2CC(C)C CHEMBL218628 Ki 1.7 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL208487 Ki 1.9 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SC(C)C)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL206229 Ki 2.2 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(S[C@@H]3CCC[C@H]3O)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL204848 Ki 2.7 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SC3CCCC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL383696 Ki 3.2 nM
CON(C)C(=O)c1c(Cn2c(C)nc(Cl)c2Cl)sc2c1c(=O)n(C)c(=O)n2CC(C)C CHEMBL387125 Ki 3.2 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3ccnc4ccccc34)sc21 CHEMBL205742 pKi 3.311 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC=CC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL1221551 pKi 3.388 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC(C)(O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL439871 Ki 3.5 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3cncc4ccccc34)sc21 CHEMBL207100 Ki 3.9 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(C#CCCCNC(=O)[C@@H](N)CCC(N)=O)c4ccccc34)cc12 CHEMBL3818851 EC50 4.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@H](O)C3)c(Cc3cccc4ccc(F)cc34)sc21 CHEMBL218987 Activity 4.1 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3c[nH]c4ncccc34)sc21 CHEMBL205092 Ki 4.7 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC[C@@H](O)C3)c(Cc3cccc4ncccc34)sc21 CHEMBL204476 Ki 5.3 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CCCC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL383669 pKi 5.495 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SC3CCCCC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL377309 Ki 6.0 nM
CCSc1c(Cc2ccccc2C(F)(F)F)sc2c1c(=O)n(C)c(=O)n2CC(C)C CHEMBL381098 Ki 6.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SCC(O)CO)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL205364 Ki 6.5 nM
CNc1nc2ccccc2n1Cc1sc2c(c1C(=O)N1CC[C@@H](O)C1)c(=O)n(C)c(=O)n2CC(C)C CHEMBL426851 Ki 6.6 nM
COc1cc(N(c2ccccc2)c2ccccc2)ccc1/C=C(\C#N)C(=O)O CHEMBL3582422 IC50 8.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CCCCC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL205465 Ki 8.7 nM
CCCCN(CCCC)c1ccc(/C=C(\C#N)C(=O)O)c(OC)c1 CHEMBL3582419 IC50 9.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CCC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL380673 Ki 9.2 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(Br)c4ccccc34)cc12 CHEMBL3817902 EC50 11.0 nM
COc1cc(N(CC(C)C)CC(C)C)ccc1/C=C(\C#N)C(=O)O CHEMBL3582420 IC50 11.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(S(=O)(=O)[C@@H]3CC[C@H](O)C3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL379399 Ki 12.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(SC3CCC3)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL205289 Ki 13.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2cn(Cc3cccc4ccccc34)cc21 CHEMBL315970 pKi 15.49 nM
Cc1nc2ccccc2n1Cc1sc2c(c1C(=O)N1CC[C@@H](O)C1)c(=O)n(C)c(=O)n2CC(C)C CHEMBL204772 Ki 16.0 nM
CC(C)Cc1nn(C)c(=O)c2cn(Cc3ccc(N=[N+]=[N-])c([125I])c3)cc12 CHEMBL1221509 Ki 23.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cc(NCCCCCN)nc4ccccc34)cc12 CHEMBL3818095 EC50 24.0 nM
COc1cc(N2CCCCC2)ccc1/C=C(\C#N)C(=O)O CHEMBL3582501 IC50 25.0 nM
Cc1nc(Cl)c(Cl)n1Cc1sc2c(c1C(=O)N1CC[C@@H](O)C1)c(=O)n(C)c(=O)n2CC(C)C CHEMBL205245 Ki 26.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3C[C@@H](O)[C@@H](O)C3)c(Cc3ccnc4ccccc34)sc21 CHEMBL373974 Ki 29.0 nM
CCCCCN(CCCCC)c1ccc(/C=C(\C#N)C(=O)O)c(OC)c1 CHEMBL3582421 IC50 34.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N(C)C)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL208330 Ki 37.0 nM
COc1cc(N(Cc2ccccc2)Cc2ccccc2)ccc1/C=C(\C#N)C(=O)O CHEMBL3892299 IC50 37.0 nM
COc1cc(N2CCCC2)ccc1/C=C(\C#N)C(=O)O CHEMBL3582500 IC50 48.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cnc(Cl)c4ccccc34)cc12 CHEMBL3818980 EC50 55.0 nM
CNc1nc2ccccc2n1Cc1sc2c(c1C(=O)N1CCC1)c(=O)n(C)c(=O)n2CC(C)C CHEMBL219483 Ki 59.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cc(Cl)nc4ccccc34)cc12 CHEMBL3818923 EC50 60.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(OC)cc2)c2ccccc12 CHEMBL5435709 IC50 81.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(C)cn2)c2ccccc12 CHEMBL5419493 IC50 82.3 nM
N#C/C(=C\c1ccc(O)cc1)C(=O)O CHEMBL76602 IC50 87.2 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(NCCCCCNC(=O)[C@@H](N)CCC(N)=O)nc3)cc12 CHEMBL3819279 EC50 100.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccccc2C)c2ccccc12 CHEMBL5401494 IC50 105.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2cccc(OC)c2)c2ccccc12 CHEMBL5405329 IC50 105.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc3ccccc3c2)c2ccccc12 CHEMBL5394985 IC50 109.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2c(Cl)cccc2Cl)c2ccccc12 CHEMBL5433941 IC50 109.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2cccnc2)c2ccccc12 CHEMBL5409450 IC50 109.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(C)cc2)c2ccccc12 CHEMBL5440350 IC50 112.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2nc(/C=C\CCCO)c(Cc3cccc4ccccc34)nc21 CHEMBL3326270 IC50 116.0 nM
CC(C)n1c(=O)n(C)c(=O)c2c(C(=O)N(C)C)c(Cc3ccccc3C(F)(F)F)sc21 CHEMBL219311 Ki 117.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccccc2OC)c2ccccc12 CHEMBL5421503 IC50 135.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2nc(CCCCCO)c(Cc3cccc4ccccc34)nc21 CHEMBL3326265 IC50 192.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2cccc3ccccc23)c2ccccc12 CHEMBL5397576 IC50 193.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(Cl)cc2)c2ccccc12 CHEMBL5427293 IC50 196.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccccn2)c2ccccc12 CHEMBL5431419 IC50 198.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(Br)cn2)c2ccccc12 CHEMBL5439235 IC50 214.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(Br)cc2)c2ccccc12 CHEMBL5402273 IC50 287.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccccc2)c2ccccc12 CHEMBL5402599 IC50 314.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(NCCCCCN)nc3)cc12 CHEMBL3818476 EC50 420.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccnc(NCCCCCNC(=O)[C@@H](N)CCC(N)=O)c3)cc12 CHEMBL3818991 EC50 500.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccnc(NCCCCCN)c3)cc12 CHEMBL3819278 EC50 520.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2c1nc(Cc1cccc3ccccc13)c(=O)n2CCCCO CHEMBL3326256 IC50 548.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2nc(SCCCCO)c(Cc3cccc4ccccc34)nc21 CHEMBL3326259 IC50 669.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(Cl)nc3)cc12 CHEMBL3819158 EC50 690.0 nM
COC(=O)/C(C#N)=C/c1cn(CC(=O)Nc2ccc(F)cc2)c2ccccc12 CHEMBL5427387 IC50 793.0 nM
CC(C)Cn1c(=O)n(C)c(=O)c2nc(SCCCO)c(Cc3cccc4ccccc34)nc21 CHEMBL3326252 IC50 858.0 nM
CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccnc(Cl)c3)cc12 CHEMBL3818005 EC50 1000.0 nM