COc1ccccc1N1CCCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781913 IC50 8.0 nM
COc1ccc(F)cc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3780239 IC50 10.0 nM
CCC(C)(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1 CHEMBL4645691 IC50 12.0 nM
CC(C)(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COCC3)c1 CHEMBL4647311 IC50 26.0 nM
CCC(CC)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COCC3)c1 CHEMBL4634839 IC50 33.0 nM
COc1ccc(C(N)=O)cc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781331 IC50 37.0 nM
COc1cc(F)ccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3780972 IC50 40.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2F)CC1 CHEMBL3781548 IC50 40.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccc(F)cc2)CC1 CHEMBL3781151 IC50 46.0 nM
O=C(COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1)NC1CCCC1 CHEMBL4634011 IC50 47.0 nM
COc1ccc(C#N)cc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3780144 IC50 50.0 nM
CC(C)(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CNCC3)c1 CHEMBL4633651 IC50 58.0 nM
Oc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781149 IC50 60.0 nM
COc1ccncc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3780372 IC50 60.0 nM
COc1ccccc1N1CCN(c2ncnc3c2ncn3-c2ccccc2)CC1 CHEMBL3780785 IC50 64.0 nM
O=C(COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1)NC1CCC1 CHEMBL4638234 IC50 68.0 nM
N#Cc1cccc(N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)c1 CHEMBL3780717 IC50 69.0 nM
COc1cccnc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781835 IC50 70.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cc(F)cc(F)c2)CC1 CHEMBL3780460 IC50 90.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cccc(C)c2)CC1 CHEMBL3780043 IC50 96.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1 CHEMBL4648466 IC50 97.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2OC)CC1 CHEMBL3780235 IC50 110.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1C CHEMBL3781308 IC50 120.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cccc(F)c2)CC1 CHEMBL3781741 IC50 120.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3C2CCCC2)CC1 CHEMBL3780527 IC50 120.0 nM
CCC(CC)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CNCC3)c1 CHEMBL4637134 IC50 121.0 nM
O=C(COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CNCC3)c1)NC1CCCC1 CHEMBL4635564 IC50 138.0 nM
CC(C)(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C2CCOC2)CC3)c1 CHEMBL4634012 IC50 155.0 nM
O=C(COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1)NCC(F)(F)F CHEMBL4635844 IC50 160.0 nM
COc1cc(C#N)ccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781183 IC50 170.0 nM
COc1cccc(-n2ncc3c(N4CCN(c5ccccc5OC)CC4)ncnc32)c1 CHEMBL3780772 IC50 170.0 nM
COc1ccc(-n2ncc3c(N4CCN(c5ccccc5OC)CC4)ncnc32)cc1 CHEMBL3781625 IC50 170.0 nM
COCCN1CCc2nc(-c3cccc(OCC(=O)NC(C)(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4638542 IC50 175.0 nM
CC1(NC(=O)COc2cccc(-c3nc4c(c(Nc5ccc(-c6cn[nH]c6)cc5)n3)CN(C3CCC3)CC4)c2)CC1 CHEMBL4647401 IC50 179.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccc(C#N)cc2)CC1 CHEMBL3781194 IC50 200.0 nM
CC1(NC(=O)COc2cccc(-c3nc4c(c(Nc5ccc(-c6cn[nH]c6)cc5)n3)CN(C3CC3)CC4)c2)CC1 CHEMBL4645036 IC50 211.0 nM
CC(CF)N1CCc2nc(-c3cccc(OCC(=O)NC(C)(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4649311 IC50 232.0 nM
O=C(COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1)NC1CC1 CHEMBL4649021 IC50 238.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C2CCC2)CC3)c1 CHEMBL4642809 IC50 238.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781157 IC50 250.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2C)CC1 CHEMBL3781347 IC50 250.0 nM
COCC(C)N1CCc2nc(-c3cccc(OCC(=O)NC(C)(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4642046 IC50 275.0 nM
CC(C)(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C2CCC2)CC3)c1 CHEMBL4632395 IC50 287.0 nM
CCCNC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1 CHEMBL4632920 IC50 298.0 nM
COc1cccc(N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)c1 CHEMBL3781827 IC50 320.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cc(F)ccc2OC)CC1 CHEMBL3780470 IC50 320.0 nM
O=C(COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1)Nc1ccccc1 CHEMBL4649877 IC50 325.0 nM
COc1ccc(-n2ncc3c(N4CCN(c5ccccc5OC)CC4)ncnc32)cn1 CHEMBL3780595 IC50 340.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cccc(C#N)c2)CC1 CHEMBL3780765 IC50 350.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CNCC3)c1 CHEMBL4637262 IC50 365.0 nM
CN1CCc2nc(-c3cccc(OCC(=O)NC(C)(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4638502 IC50 368.0 nM
CN1CCc2nc(-c3cccc(OCC(=O)NC4CCCC4)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4633530 IC50 391.0 nM
CCC(C)(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C)CC3)c1 CHEMBL4635864 IC50 391.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C2(C)CC2)CC3)c1 CHEMBL4648189 IC50 392.0 nM
CC(C)N1CCc2nc(-c3cccc(OCC(=O)NC(C)(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4648473 IC50 412.0 nM
COc1ccccc1N1CCN(c2ncnc3c2nnn3-c2ccccc2)CC1 CHEMBL3781384 IC50 430.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)C(C)C1 CHEMBL3781633 IC50 480.0 nM
CCN1CCc2nc(-c3cccc(OCC(=O)NC(C)(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4641999 IC50 482.0 nM
Fc1cccc(N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)c1 CHEMBL3781994 IC50 540.0 nM
COc1c(C#N)cccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3781447 IC50 540.0 nM
CC(C)N1CCc2nc(-c3cccc(OCC(=O)NC4CCCC4)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4638556 IC50 548.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C2CC2)CC3)c1 CHEMBL4645662 IC50 548.0 nM
CN1CCc2nc(-c3cccc(OCC(=O)NC4CCC4)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4637311 IC50 566.0 nM
CCC(CC)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C)CC3)c1 CHEMBL4647586 IC50 584.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C(C)C)CC3)c1 CHEMBL4640792 IC50 619.0 nM
COc1ccccc1N1CCN(c2ncnc3c2[nH]c(=O)n3-c2ccccc2)CC1 CHEMBL3780054 IC50 630.0 nM
Fc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3780459 IC50 680.0 nM
COc1ncccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 CHEMBL3780764 IC50 680.0 nM
CCN(CC)C(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)COC3)c1 CHEMBL4645739 IC50 686.0 nM
CC(C)CNC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C(C)C)CC3)c1 CHEMBL4649211 IC50 802.0 nM
CC(C)CNC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C)CC3)c1 CHEMBL4637272 IC50 846.0 nM
CCN1CCc2nc(-c3cccc(OCC(=O)NC(C)C)c3)nc(Nc3ccc(-c4cn[nH]c4)cc3)c2C1 CHEMBL4649871 IC50 846.0 nM
CC(C)NC(=O)COc1cccc(-c2nc3c(c(Nc4ccc(-c5cn[nH]c5)cc4)n2)CN(C)CC3)c1 CHEMBL4634395 IC50 867.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccccn2)CC1 CHEMBL3780349 IC50 940.0 nM
COc1ccccc1N1CCN(c2ncnc3c2cnn3C(C)c2ccccc2)CC1 CHEMBL3780729 IC50 950.0 nM