CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\P(=O)(OCC)OCC)P(=O)(OCC)OCC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393878 EC50 1.1 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393870 EC50 4.2 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)CNCC(=O)O)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3623057 EC50 4.2 nM
O=C(NCc1ncccc1F)c1coc(CCN(CCc2nc3ccccc3[nH]2)CCc2nc3ccccc3[nH]2)n1 CHEMBL4564862 EC50 6.0 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393871 EC50 6.3 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\C(N)=O)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393877 EC50 8.4 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\S(=O)(=O)C(C)(C)C)S(=O)(=O)C(C)(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393876 EC50 10.0 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\C(=O)OCC)C(=O)OCC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393872 EC50 10.4 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\C(=O)OC)C(=O)OC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393873 EC50 12.6 nM
O=C(NCc1ncccc1F)c1cnc(CCNCCc2nc3ccccc3[nH]2)o1 CHEMBL4587045 IC50 16.0 nM
O=C(NCc1ncccc1F)c1cnc(C2CN(CCc3nc4ccccc4[nH]3)C2)o1 CHEMBL4462224 IC50 17.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3cc(F)ccc3[nH]2)n1 CHEMBL4442485 IC50 19.0 nM
O=C(NCc1ncccc1F)c1coc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 CHEMBL4565338 IC50 19.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)cccc3[nH]2)n1 CHEMBL4468502 IC50 21.0 nM
CCCCCCCCCCCCCCCC(=O)NCCCOCCOCCOCCCNC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)CNCC(=O)O)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL4527595 EC50 21.0 nM
CC[C@H](C)[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)[C@@H](C)O)[C@@H](C)CC)CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)O)[C@@H](C)O)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@@H]4CSSC[C@H](NC(=O)[C@H](Cc5ccccc5)NC1=O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1cnc[nH]1)NC3=O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N2)C(=O)NCC(=O)N4 CHEMBL4455858 EC50 22.0 nM
O=C(NCc1ncccc1F)c1csc(CCN(CCc2nc3ccccc3[nH]2)CCc2nc3ccccc3[nH]2)n1 CHEMBL4575243 IC50 23.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4475199 IC50 23.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(Cl)cccc3[nH]2)n1 CHEMBL4581730 IC50 26.0 nM
O=C(NCc1ncccc1F)c1nc(CCNCCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4470632 IC50 30.0 nM
O=C(NCc1ncccc1Cl)c1coc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4456285 IC50 31.0 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C(=C\S(N)(=O)=O)c1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393875 EC50 34.0 nM
O=C(NCc1ncccc1F)c1csc(CCNCCc2nc3c(F)cccc3[nH]2)n1 CHEMBL4589376 IC50 34.0 nM
O=C(NCc1ncccc1Cl)c1nc(CCNCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4441062 IC50 35.0 nM
O=C(NCc1ncccc1F)c1coc(CNCCc2nc3ccccc3[nH]2)n1 CHEMBL4459067 IC50 36.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)c(F)ccc3[nH]2)n1 CHEMBL4445738 IC50 38.0 nM
O=C(NCc1ncccc1F)c1coc(C2CN(CCc3nc4c(F)cccc4[nH]3)C2)n1 CHEMBL4520569 IC50 38.0 nM
O=C(NCc1ncccc1F)c1nc(C2CN(CCc3nc4ccccc4[nH]3)C2)sc1Cl CHEMBL4473202 IC50 38.0 nM
O=C(NC1CCc2cccnc21)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4573733 IC50 41.0 nM
O=C(NCc1ncccc1Cl)c1cnn(CCNCCc2nc3ccccc3[nH]2)c1 CHEMBL4476775 EC50 43.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)cc(F)cc3[nH]2)n1 CHEMBL4579471 IC50 44.0 nM
O=C(NCc1ncccc1F)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4539480 IC50 44.0 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@@H]1CSCc2cccc(c2)CSC[C@H](NC(C)=O)C(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1 CHEMBL3623073 EC50 44.2 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(C(F)(F)F)cccc3[nH]2)n1 CHEMBL4456611 IC50 46.0 nM
O=C(NCc1ccccn1)c1coc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 CHEMBL4462521 IC50 47.0 nM
O=C(NCc1ccccn1)c1nc(CCN2CCc3nc4ccccc4n3C2)sc1Cl CHEMBL4536483 IC50 47.0 nM
O=C(NCc1ncccc1Cl)c1coc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4518192 IC50 49.0 nM
O=C(NCc1ncccc1F)c1cnn(CCNCCc2nc3ccccc3[nH]2)c1 CHEMBL4585912 IC50 51.0 nM
O=C(NCc1ncccc1F)c1cnc(C2CN(CCc3nc4cc(F)ccc4[nH]3)C2)o1 CHEMBL4585288 IC50 51.1 nM
CCCCCCCCCCCCCCCC(=O)NCCOCCOCCNC(=O)[C@@H]1CSCc2cccc(c2)CSC[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1 CHEMBL3621378 EC50 52.3 nM
CC(=O)N[C@H]1CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(c2ccccc2)c2ccccc2)NC1=O CHEMBL3623071 EC50 54.3 nM
Cc1oc(CCNCCc2nc3ccccc3[nH]2)nc1C(=O)NCc1ncccc1F CHEMBL4580803 IC50 58.0 nM
O=C(NCc1ncc(F)cc1F)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4562191 IC50 58.0 nM
Cc1sc(CCNCCc2nc3ccccc3[nH]2)nc1C(=O)NCc1ncccc1F CHEMBL4440019 IC50 61.0 nM
O=C(NCc1ccccn1)c1coc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4442719 IC50 66.0 nM
O=C(NCc1ncccc1F)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4593358 IC50 68.0 nM
O=C(NCc1ncccc1F)c1cn(CCNCCc2nc3ccccc3[nH]2)nn1 CHEMBL4528718 EC50 69.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)ccc(F)c3[nH]2)n1 CHEMBL4543450 IC50 71.0 nM
O=C(NCc1ncccc1F)c1csc(CCNCCc2nc3cc(F)ccc3[nH]2)n1 CHEMBL4443017 IC50 71.0 nM
O=C(NCc1ncccc1F)c1cnc(C2CN(CCc3nc4c(F)cccc4[nH]3)C2)o1 CHEMBL4454025 IC50 71.0 nM
O=C(NCc1ncccc1F)c1csc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 CHEMBL4586976 IC50 74.0 nM
C[C@@H](O)[C@H](NC(=O)CNCC(=O)O)C(=O)N[C@H]1CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(c2ccccc2)c2ccccc2)NC1=O CHEMBL3623072 EC50 75.1 nM
O=C(NCc1ccccn1)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4464039 IC50 76.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(C)=O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)O CHEMBL4547955 IC50 76.0 nM
O=C(NCc1ncccc1Cl)c1csc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 CHEMBL4436976 IC50 77.0 nM
Cc1cccnc1CNC(=O)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4573402 IC50 87.0 nM
O=C(NCc1ncccc1F)c1ncn(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4587530 IC50 89.0 nM
O=C(NCc1ncccc1F)c1nc(CCNCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4553819 IC50 89.0 nM
N=C(N)NCCC[C@@H]1NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(c2ccccc2)c2ccccc2)NC(=O)CCSCc2cccc(c2)CSC[C@@H](C(=O)NCCOCCOCCN)NC(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3621375 EC50 92.3 nM
Cn1nc(CNCCc2nc3ccccc3[nH]2)cc1C(=O)NCc1ncccc1F CHEMBL4444990 IC50 93.0 nM
COc1cccc2[nH]c(CCNCCc3nc(C(=O)NCc4ncccc4F)co3)nc12 CHEMBL4452538 IC50 96.0 nM
O=C(NCc1ccccn1)c1nc(CCNCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4442044 IC50 97.0 nM
O=C(NCc1ccccn1)c1nc(CCNCCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4536578 IC50 100.0 nM
N=C(N)NCCC[C@@H]1NC(=O)[C@@H](NC(=O)CC(c2ccccc2)c2ccccc2)CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC1=O CHEMBL3621370 EC50 103.8 nM
O=C(NCc1ncccc1F)c1cnn(C2CN(CCc3nc4ccccc4[nH]3)C2)c1 CHEMBL4449588 IC50 104.0 nM
O=C(NCc1ncc(F)cc1F)c1csc(CCNCCc2nc3cc(F)ccc3[nH]2)n1 CHEMBL4549900 IC50 112.0 nM
N=C(N)NCCC[C@@H]1NC(=O)[C@@H](NC(=O)CC(c2ccccc2)(c2ccccc2)c2ccccc2)CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC1=O CHEMBL3621371 EC50 112.7 nM
O=C(NCc1ncccc1F)c1coc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4516922 IC50 120.0 nM
O=C(NCc1ccccn1)c1coc(CCNCCc2nc3c(F)cccc3[nH]2)n1 CHEMBL4458066 IC50 123.0 nM
O=S1(=O)Nc2c(ccc3cccnc23)-c2cc(C(F)(F)F)ccc21 CHEMBL272552 IC50 130.0 nM
O=C(NC1CCc2cccnc21)c1cnn(CCNCCc2nc3ccccc3[nH]2)c1 CHEMBL4592063 IC50 133.0 nM
O=C(NCc1ncccc1F)c1nc(CCNCCc2nc3ccccc3[nH]2)sc1C(F)(F)F CHEMBL4532240 IC50 140.0 nM
Cc1sc(CCNCc2nc3ccccc3[nH]2)nc1C(=O)NCc1ncccc1F CHEMBL4453697 IC50 140.0 nM
O=C(NCc1ncccc1F)c1cn(CCNCCc2nc3ccccc3[nH]2)nc1C(F)(F)F CHEMBL4473798 IC50 140.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCc2nc3c(F)cccc3[nH]2)n1 CHEMBL4461241 IC50 148.1 nM
O=C(NCc1ncccc1F)c1nc(C2(O)CN(CCc3nc4ccccc4[nH]3)C2)sc1Cl CHEMBL4516298 IC50 154.0 nM
O=C(NCc1ncccc1Cl)c1cnn(CCNCc2nc3ccccc3[nH]2)c1 CHEMBL4447099 IC50 160.0 nM
CC(=O)N[C@H]1CSCc2cccc(c2)CSC[C@@H](C(=O)NCCOCCOCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(c2ccccc2)c2ccccc2)NC1=O CHEMBL3621374 EC50 164.5 nM
O=C(NCc1ccccn1)c1cnn(CCNCCc2nc3ccccc3[nH]2)c1 CHEMBL4449134 IC50 172.0 nM
O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)ccc(Cl)c3[nH]2)n1 CHEMBL4449419 IC50 178.0 nM
Cc1nc(CCNCCc2nc3ccccc3[nH]2)sc1C(=O)NCc1ncccc1F CHEMBL4443815 IC50 180.0 nM
O=C(NCc1cccnn1)c1coc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 CHEMBL4581028 IC50 182.0 nM
O=C(NCc1cccnn1)c1nc(CCNCCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4464796 IC50 190.0 nM
O=C(NCc1ccccn1)c1coc(C2CN(CCc3nc4c(F)cccc4[nH]3)C2)n1 CHEMBL4569416 IC50 194.0 nM
O=C(NCc1cccnn1)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 CHEMBL4468807 IC50 214.0 nM
CCCCCCCCCCCCCCCCNC(=O)CN(CC(N)=O)C(=O)CCCCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS/C=C\C(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)CNC(=O)CO)[C@@H](C)O)C(c1ccccc1)c1ccccc1 CHEMBL3393874 EC50 218.1 nM
O=C(NCc1ncccc1F)c1csc(CCNCc2nc3ccc(F)cc3[nH]2)n1 CHEMBL4452473 IC50 230.0 nM
O=C(NC1CCCc2cccnc21)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4576379 IC50 233.0 nM
CN1C(c2ccc(F)c(F)c2)c2ccc3cccnc3c2NS1(=O)=O CHEMBL3969259 IC50 250.0 nM
CC(=O)c1cc2c(c3ncccc13)NS(=O)(=O)N(C)C2c1ccc(F)cc1 CHEMBL3904075 IC50 250.0 nM
O=C(NCc1ncccc1F)c1csc(CNCCc2nc3ccccc3[nH]2)n1 CHEMBL4439059 IC50 250.0 nM
O=C(NCc1ncc(F)cc1Cl)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4530497 IC50 258.0 nM
O=C(NCc1cccnn1)c1nc(CCNCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4574441 IC50 260.0 nM
N=C(N)NCCC[C@@H]1NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)CSCc2cccc(c2)CSCCNC(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3621373 EC50 268.8 nM
COc1cccnc1CNC(=O)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4573779 IC50 270.0 nM
CC(=O)N[C@H]1CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3623062 EC50 272.2 nM
O=C(NCc1ncccc1Cl)c1ncn(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4465580 IC50 280.0 nM
O=C(NCc1ncccc1F)c1cnc(CCNCCc2nc3ccccc3[nH]2)s1 CHEMBL4436342 IC50 282.0 nM
O=C(NCc1ncccc1F)c1nc(CNCCc2nc3ccccc3[nH]2)cs1 CHEMBL4541033 IC50 290.0 nM
CC[C@H](C)[C@H](NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]2C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O CHEMBL3621383 EC50 300.0 nM
Cc1ccc(S(=O)(=O)Nc2cccc3cccnc23)c(N)c1 CHEMBL3896154 IC50 300.0 nM
O=C(Nc1ccccc1S(=O)(=O)Nc1cccc2cccnc12)C(F)(F)F CHEMBL3912604 IC50 307.0 nM
O=C(NCc1ncc(C(F)(F)F)cc1Cl)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4558277 IC50 315.0 nM
O=S1(=O)Nc2c(cc(Cl)c3cccnc23)-c2ccccc21 CHEMBL3894587 IC50 320.0 nM
Cc1ccc(CNC(=O)c2csc(CCNCCc3nc4ccccc4[nH]3)n2)nn1 CHEMBL4586182 IC50 320.0 nM
Cc1cnc(CNC(=O)c2nc(CCNCCc3nc4ccccc4[nH]3)sc2Cl)nc1 CHEMBL4531764 IC50 330.0 nM
N=C(N)NCCC[C@@H]1NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3621372 EC50 335.3 nM
CN1C(c2ccc(F)cc2)c2ccc3cccnc3c2NS1(=O)=O CHEMBL3959067 IC50 340.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(C)=O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCOCCOCCOCC(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCNC(=O)CCCCCNC(=O)CCC1=C(C)C2=Cc3ccc(-c4ccc(OC)cc4)n3[B-](F)(F)[N+]2=C1C)C(=O)O CHEMBL4565592 EC50 347.0 nM
O=C(NCc1ncccc1F)c1cnn(CCNCc2nc3ccccc3[nH]2)c1 CHEMBL4458884 IC50 350.0 nM
Cc1ccc2c(c1)S(=O)(=O)Nc1c-2ccc2cccnc12 CHEMBL3933529 IC50 360.0 nM
CCCCCCCCCCCCCCCC(=O)N[C@H]1CSCc2cccc(c2)CSCCNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(c2ccccc2)c2ccccc2)NC1=O CHEMBL3621377 EC50 369.0 nM
O=C(NCc1ncccc1F)c1csc(CCN(Cc2nc3ccccc3[nH]2)Cc2nc3ccccc3[nH]2)n1 CHEMBL4555900 IC50 370.0 nM
O=C(NCc1ncccc1Cl)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4521298 IC50 374.0 nM
Cc1ccc(S(=O)(=O)Nc2cccc3cccnc23)nc1 CHEMBL3919322 IC50 380.0 nM
N#Cc1cccc(S(=O)(=O)Nc2cccc3cccnc23)c1 CHEMBL3966573 IC50 413.0 nM
Cc1cnccc1CNC(=O)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4471349 IC50 418.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1ccccc1C(F)(F)F CHEMBL3956864 IC50 419.0 nM
O=S1(=O)Nc2c(cc(Cl)c3cccnc23)-c2cc(OC3CCCC3)ccc21 CHEMBL3958839 IC50 420.0 nM
O=C(NCCCN(CCc1nc2ccccc2[nH]1)CCc1nc(C(=O)NCc2ncccc2F)cs1)OCc1ccccc1 CHEMBL4461453 IC50 420.0 nM
Cc1cc(C)c(CNC(=O)c2csc(CCNCc3nc4ccccc4[nH]3)n2)cn1 CHEMBL4457888 IC50 420.0 nM
Cc1cnc(CNC(=O)c2csc(CCNCc3nc4ccccc4[nH]3)n2)c(C)c1 CHEMBL4593321 IC50 430.0 nM
O=C(NCc1cccnn1)c1coc(C2CN(CCc3nc4c(F)cccc4[nH]3)C2)n1 CHEMBL4447684 IC50 439.6 nM
CC(C)(CNCCc1nc(C(=O)NCc2ncccc2F)cs1)c1nc2ccccc2[nH]1 CHEMBL4434703 IC50 450.0 nM
O=C(NCc1ccccc1OC(F)F)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4447237 IC50 451.0 nM
CCCCCCCCCCCCCCCC(=O)N[C@@H](C(=O)N[C@H]1CSCc2cccc(c2)CSCCNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC1=O)C(c1ccccc1)c1ccccc1 CHEMBL3621380 EC50 458.3 nM
O=S1(=O)Nc2c(ccc3cccnc23)CN1c1ccccc1 CHEMBL3930846 IC50 460.0 nM
O=S(=O)(Nc1ccc(C(F)(F)F)c2cccnc12)c1ccccn1 CHEMBL3908826 IC50 460.0 nM
Cc1cnc(CNC(=O)c2csc(CCNCCc3nc4ccccc4[nH]3)n2)nc1 CHEMBL4567247 IC50 460.0 nM
CC(=O)N[C@H]1CSCc2ccc(cc2)Oc2ccc(cc2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3623066 EC50 477.4 nM
O=C(NCc1ncc(F)cc1F)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4449812 IC50 478.0 nM
N#Cc1ccccc1CNC(=O)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4470704 IC50 508.0 nM
CC(=O)N[C@H]1CSCc2cccc(c2)Cc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3623067 EC50 516.9 nM
O=C(NC1CCc2cccnc21)c1cnn(C2CN(CCc3nc4ccccc4[nH]3)C2)c1 CHEMBL4438321 IC50 520.0 nM
C[C@@H](O)[C@H](NC(=O)CNCC(=O)O)C(=O)N[C@H]1CSCc2cccc(c2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3623070 EC50 531.7 nM
O=C(NCc1ncccc1F)c1ncn(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4445222 IC50 540.0 nM
COCCN(C)c1cc2c(c3ncccc13)NS(=O)(=O)c1ccccc1-2 CHEMBL3914817 IC50 550.0 nM
N#Cc1ccc(CNC(=O)c2csc(CCNCc3nc4ccccc4[nH]3)n2)cn1 CHEMBL4520521 IC50 566.0 nM
O=C(NC1CCc2cccnc21)c1cnn(CCNCc2nc3ccccc3[nH]2)c1 CHEMBL4553638 IC50 570.0 nM
O=C(NCc1ncccc1F)c1csc(CCNCc2nc3c(F)cccc3[nH]2)n1 CHEMBL4588189 EC50 582.0 nM
COc1cc(NS(=O)(=O)c2ccc(C)cc2N)c2ncccc2c1 CHEMBL256061 IC50 585.0 nM
CC(=O)N[C@H]1CSCc2ccc(cc2)CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3623061 EC50 585.6 nM
CC(=O)N[C@H]1CSCc2ccccc2CSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O CHEMBL3623063 EC50 598.9 nM
Cc1cc2c(c3ncccc13)NS(=O)(=O)c1ccccc1-2 CHEMBL3965000 IC50 599.0 nM
Cc1ccc(C2c3ccc4cccnc4c3NS(=O)(=O)N2C)cc1 CHEMBL3914642 IC50 600.0 nM
Cc1cnc2c(NS(=O)(=O)c3ccccc3)cccc2c1 CHEMBL3933701 IC50 610.0 nM
O=S1(=O)Nc2c(cc(Cl)c3cccnc23)-c2cc(NCCN3CCOCC3)ccc21 CHEMBL3976830 IC50 620.0 nM
Cc1sc(CCNCCc2nc3ccccc3[nH]2)nc1C(=O)NCc1ncccn1 CHEMBL4551530 IC50 630.0 nM
O=S(=O)(Nc1cc(F)cc2cccnc12)c1ccc(Cl)cc1F CHEMBL3919719 IC50 690.0 nM
O=C(NCc1ncccc1F)c1cn(CCNCc2nc3ccccc3[nH]2)nc1C(F)(F)F CHEMBL4435821 IC50 710.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1cccc(C(F)(F)F)c1 CHEMBL3947100 IC50 720.0 nM
CN1C(c2cccc(F)c2)c2ccc3cccnc3c2NS1(=O)=O CHEMBL3927819 IC50 720.0 nM
O=C(NC1CCc2cccnc21)c1csc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 CHEMBL4591433 IC50 730.0 nM
Nc1cc(C(F)(F)F)ccc1S(=O)(=O)Nc1cccc2cccnc12 CHEMBL3979691 IC50 760.0 nM
O=S1(=O)Nc2c(ccc3cccnc23)-c2cc(Cl)ccc21 CHEMBL429599 IC50 770.0 nM
O=S(=O)(Nc1cc(F)cc2cccnc12)c1ccccc1 CHEMBL3892473 IC50 780.0 nM
N#Cc1ccccc1S(=O)(=O)Nc1cccc2cccnc12 CHEMBL3897801 IC50 815.0 nM
Cc1ccc(F)c(CNC(=O)c2csc(CCNCc3nc4ccccc4[nH]3)n2)n1 CHEMBL4466318 IC50 820.0 nM
O=C(NCc1ccccc1N1CCOCC1)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4438445 IC50 846.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1c(Cl)cc(Cl)cc1Cl CHEMBL3950354 IC50 857.0 nM
O=C(NCc1ccccn1)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4543939 IC50 860.0 nM
CN1C(c2ccccc2)c2ccc3cccnc3c2NS1(=O)=O CHEMBL3909460 IC50 870.0 nM
O=C(NCc1ncccc1F)c1nc(CCNCC(F)(F)c2nc3ccccc3[nH]2)cs1 CHEMBL4441736 IC50 870.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1ccc(Cl)cc1F CHEMBL3959566 IC50 873.0 nM
CN(C)c1ccc2c(c1)-c1ccc3cccnc3c1NS2(=O)=O CHEMBL3970065 IC50 910.0 nM
O=[N+]([O-])c1cc(F)ccc1S(=O)(=O)Nc1cccc2cccnc12 CHEMBL3900875 IC50 920.0 nM
O=C(NCc1ccncc1F)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4476517 IC50 922.0 nM
O=C(NCc1ccccc1OC(F)(F)F)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4439323 IC50 931.0 nM
O=C(NCc1ncccn1)c1nc(CCNCc2nc3ccccc3[nH]2)sc1Cl CHEMBL4464442 IC50 950.0 nM
O=C(NCc1ccccc1F)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4456427 IC50 950.0 nM
CN1C(c2ccc(C(F)(F)F)nc2)c2ccc3cccnc3c2NS1(=O)=O CHEMBL3930418 IC50 960.0 nM
COc1cc2c(c3ncccc13)NS(=O)(=O)c1ccc(C(F)(F)F)cc1-2 CHEMBL3943490 IC50 960.0 nM
O=C(NCc1ncccc1F)c1csc(CCCNCc2nc3ccccc3[nH]2)n1 CHEMBL4473424 IC50 970.0 nM
O=C(NCc1nc2ccccc2[nH]1)c1csc(CCNCc2nc3ccccc3[nH]2)n1 CHEMBL4476512 IC50 974.0 nM
COc1ccnc2c3c(ccc12)-c1cc(C(F)(F)F)ccc1S(=O)(=O)N3 CHEMBL3965273 IC50 979.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1cccc(Cl)c1 CHEMBL3950857 IC50 985.0 nM
O=S(=O)(Nc1ccc(F)c2cccnc12)c1ccccc1 CHEMBL3916835 IC50 988.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1ccc(Cl)cc1Cl CHEMBL3969674 IC50 989.0 nM
COc1cc2c(c3ncccc13)NS(=O)(=O)c1ccccc1-2 CHEMBL3919188 IC50 990.0 nM
O=C(OC1CCCC1)c1ccc2c(c1)-c1cc(Cl)c3cccnc3c1NS2(=O)=O CHEMBL3978323 IC50 990.0 nM
O=S(=O)(Nc1cccc2cccnc12)c1ccc(C(F)(F)F)cc1 CHEMBL3961534 IC50 1000.0 nM
COc1cc(NS(=O)(=O)c2ccc(C(F)(F)F)cc2N)c2ncccc2c1 CHEMBL3935005 IC50 1000.0 nM
O=S(=O)(Nc1cc(F)cc2cccnc12)c1c(F)cccc1F CHEMBL3929388 IC50 1000.0 nM