CNCC[C@@H](Oc1cc(Cl)ccc1Cl)c1ccccc1 CHEMBL1762471 IC50 0.0 nM
O=c1cccnn1C[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3819243 IC50 0.065 nM
O=c1ccccn1C[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3819201 IC50 0.079 nM
COC[C@H]1CN[C@H]2CC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL4228464 pKi 0.07943 nM
O=C1NCCCN1C[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3818117 IC50 0.08 nM
O=C1CCCCN1C[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3817915 IC50 0.1 nM
Cc1csc(C[C@H]2[C@@H]3CNC[C@@]32c2ccc(Cl)c(Cl)c2)n1 CHEMBL597000 pKi 0.1259 nM
O=C1CCCN1C[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3818953 IC50 0.13 nM
Clc1ccc([C@]23CNC[C@H]2[C@@H]3COC2CCCC2)cc1Cl CHEMBL596987 pKi 0.1585 nM
CCOC[C@H]1[C@@H]2CNC[C@@]21c1ccc(Cl)c(Cl)c1 CHEMBL608151 pIC50 0.1585 nM
COC(=O)c1cccn(C[C@@H]2CNCCO[C@H]2c2ccc(Cl)c(F)c2)c1=O CHEMBL3818901 IC50 0.21 nM
CC(C)OC[C@@H]1[C@H]2CNC[C@]21c1ccc(Cl)c(Cl)c1 CHEMBL605209 pKi 0.2512 nM
Cc1ccccc1S[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL179249 Ki 0.3 nM
CCOc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL180101 Ki 0.3 nM
Fc1ccc(F)c(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1Cl CHEMBL2338048 pIC50 0.3162 nM
CC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593400 IC50 0.33 nM
CC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL4791288 IC50 0.33 nM
CC(C)OC[C@H]1[C@@H]2CNC[C@@]21c1ccc(Cl)c(Cl)c1 CHEMBL602235 pKi 0.3981 nM
COCC[C@H]1[C@]2(C)CNC[C@]12c1ccc(Cl)c(Cl)c1 CHEMBL2021580 pIC50 0.3981 nM
Cc1csc([C@@]23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)n1 CHEMBL1818444 pKi 0.3981 nM
Cc1csc(C23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)n1 CHEMBL1818445 pKi 0.3981 nM
Clc1cccc(Cl)c1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2337605 pIC50 0.3981 nM
COc1ccccc1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2337586 pIC50 0.3981 nM
COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@H]1c1ccc(C)c(F)c1)N2 CHEMBL1812750 IC50 0.5 nM
Clc1ccc([C@]23CNC[C@H]2[C@@H]3COC2CCC2)cc1Cl CHEMBL611063 pKi 0.5012 nM
CCCOC[C@H]1[C@@H]2CNC[C@@]21c1ccc(Cl)c(Cl)c1 CHEMBL599845 pKi 0.5012 nM
CC(C)CCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224320 pKi 0.5012 nM
Fc1ccc(F)c(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1Cl CHEMBL2338049 pIC50 0.5012 nM
Clc1ccc(Cl)c(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1Cl CHEMBL2338042 pIC50 0.5012 nM
COc1cc(Cl)ccc1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2338036 pIC50 0.5012 nM
O=[N+]([O-])c1ccccc1O[C@H](c1ccccc1)[C@@H]1CCNC1 CHEMBL2337601 pIC50 0.5012 nM
Clc1cccc(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1 CHEMBL2337595 pIC50 0.5012 nM
CNCCCN1c2ccccc2CCc2ccccc21 CHEMBL72 Ki 0.6 nM
CNCC[C@H](Oc1cccc(N2CCN(C)c3nc(SC)ncc3C2=O)c1)c1cccs1 CHEMBL4750411 IC50 0.6 nM
OC1(c2ccc3c(c2)OCO3)c2ccccc2C2=NCCCN21 CHEMBL544370 IC50 0.62 nM
COC[C@@H]1[C@H]2CNC[C@]21c1ccc2ccccc2c1 CHEMBL598215 pKi 0.631 nM
CCCOC[C@@H]1[C@H]2CNC[C@]21c1ccc(Cl)c(Cl)c1 CHEMBL598825 pKi 0.631 nM
Clc1ccc([C@@]23CNC[C@@H]2[C@H]3COCC2CC2)cc1Cl CHEMBL610795 pKi 0.631 nM
Cc1cccc2nc(C(=O)C3(CCC(C)(C)C)CCNC3)ccc12 CHEMBL1224240 pKi 0.631 nM
Cc1csc(C[C@@]23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)n1 CHEMBL1818448 pKi 0.631 nM
Fc1ccc(F)c(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1F CHEMBL2338044 pIC50 0.631 nM
Cc1nnc(-c2cccn(C[C@@H]3CNCCO[C@H]3c3ccc(Cl)c(F)c3)c2=O)[nH]1 CHEMBL3818471 IC50 0.64 nM
COc1ccccc1S[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL181188 Ki 0.76 nM
CN(C)C(=O)[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593399 IC50 0.77 nM
Fc1cc(F)c(F)c(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1F CHEMBL2338052 pIC50 0.7943 nM
Fc1cc(F)c(Cl)c(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1Cl CHEMBL2338045 pIC50 0.7943 nM
Fc1cccc(F)c1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2338032 pIC50 0.7943 nM
Clc1cccc(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1Cl CHEMBL2337603 pIC50 0.7943 nM
Cc1ccccc1O[C@H](c1ccccc1)[C@@H]1CCNC1 CHEMBL2337591 pIC50 0.7943 nM
CCN(CC)C(=O)C1(c2ccccc2)CC1CN CHEMBL259209 pIC50 0.7943 nM
COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(Cl)c(C)c1)N2C CHEMBL50858 IC50 0.8 nM
CNCCCN1c2ccccc2CCc2ccccc21 CHEMBL1696 Ki 0.8 nM
OC1(c2ccc(Cl)cc2)c2cccc(F)c2C2=NCCN21 CHEMBL336100 Ki 0.9 nM
COC(=O)[C@H]1[C@@H](c2ccc(Cl)c(C)c2)C[C@@H]2CC[C@H]1N2 CHEMBL1812746 IC50 0.9 nM
OC1(c2ccc(Cl)cc2)c2ccccc2C2=NCCN21 CHEMBL781 IC50 0.92 nM
COc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL223166 Ki 0.95 nM
FCCOc1ccccc1S[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL411263 Ki 1.0 nM
Cn1ccc2cc(C3(Cc4ccccc4)CCNC3)ccc21 CHEMBL459176 Ki 1.0 nM
c1ccc(CC2(c3ccc4cc[nH]c4c3)CCNC2)cc1 CHEMBL459165 Ki 1.0 nM
c1ccc(CC2(c3ccc4[nH]ccc4c3)CCNC2)cc1 CHEMBL487355 Ki 1.0 nM
Fc1ccc(Oc2cc(F)c(F)cc2C2CCNCC2)cc1 CHEMBL574427 Ki 1.0 nM
COC[C@H]1[C@@H]2CNC[C@@]21c1ccc2ccccc2c1 CHEMBL611379 pKi 1.0 nM
CNCCCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1085338 IC50 1.0 nM
CNC[C@@H](O)CCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1082458 IC50 1.0 nM
C=CCC(OC)[C@]12CNCC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL1173087 pKi 1.0 nM
CCCCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224492 pKi 1.0 nM
Cc1cc(C)n(CC23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)n1 CHEMBL1818455 pKi 1.0 nM
Fc1cc(Cl)cc(Cl)c1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2338047 pIC50 1.0 nM
Fc1cc(F)c(Cl)c(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1Cl CHEMBL2338046 pIC50 1.0 nM
CCOC(=O)NCCNC(CC(C)C)C1(c2ccc(Cl)c(Cl)c2)CCC1 CHEMBL3704750 Ki 1.0 nM
O=c1[nH]c(-c2cccn(C[C@@H]3CNCCO[C@H]3c3ccc(Cl)c(F)c3)c2=O)no1 CHEMBL3818345 IC50 1.0 nM
Cc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL467432 Ki 1.02 nM
CCOc1ccccc1OC(c1ccccc1)C1CNCCO1 CHEMBL14370 Ki 1.1 nM
CNCCCC1c2ccccc2C=Cc2ccccc21 CHEMBL668 IC50 1.1 nM
CNCCCCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1085831 IC50 1.1 nM
COC(=O)[C@H]1[C@@H](c2ccc(Cl)c(C)c2)C[C@@H]2CC[C@H]1N2C CHEMBL1812745 IC50 1.1 nM
O=C(O)c1cccn(C[C@@H]2CNCCO[C@H]2c2ccc(Cl)c(F)c2)c1=O CHEMBL3819441 IC50 1.1 nM
CNC[C@@H]1C[C@@]1(Oc1cccc2ccccc12)c1cccs1 CHEMBL553224 Ki 1.19 nM
COc1ccc(O[C@@H](CC(C)C)[C@H]2CCNC2)c(C)n1 CHEMBL2386163 Ki 1.2 nM
CN1Cc2ccccc2C(c2ccc3sccc3c2)C1 CHEMBL3323095 Ki 1.2 nM
CNC[C@H](c1ccc2ccccc2c1)[C@H](O)c1ccccc1 CHEMBL4227444 Ki 1.2 nM
COCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL4753874 IC50 1.2 nM
FCCCOc1ccccc1S[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL411262 Ki 1.21 nM
Clc1ccc([C@]23CNC[C@H]2[C@@H]3COC2CCC2)cc1Cl CHEMBL608430 pKi 1.259 nM
CC(C)CC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224490 pKi 1.259 nM
CC(C)(C)CCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224321 pKi 1.259 nM
Clc1ccc(Cl)c(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1Cl CHEMBL2338043 pIC50 1.259 nM
Cc1ccc2c(c1)CN(C)CC2c1ccc2sccc2c1 CHEMBL3323173 IC50 1.3 nM
COC(=O)c1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL272002 Ki 1.32 nM
COC(=O)c1ccccc1S[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL270099 Ki 1.35 nM
COC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C CHEMBL311347 Ki 1.4 nM
CC(C)CN(Cc1ccccc1Cl)C1CCNCC1 CHEMBL208251 Ki 1.4 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1CC(C)(C)c2cccc(F)c21 CHEMBL598614 IC50 1.4 nM
CN1Cc2cc(-c3cccnn3)ccc2C(c2ccc3sccc3c2)C1 CHEMBL3663917 Ki 1.4 nM
O=c1c(-c2nnn[nH]2)cccn1C[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3818946 IC50 1.4 nM
COC[C@@H]1CN[C@H]2CC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL4227688 pKi 1.413 nM
COc1ccc2c(c1)C(O)(c1ccc(Cl)cc1)N1CCN=C21 CHEMBL132082 IC50 1.46 nM
CCc1ccccc1O[C@H]1c2ccccc2C[C@@]1(O)CNC CHEMBL502379 IC50 1.5 nM
CCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL4754287 IC50 1.5 nM
CC(C)OCC[C@]1(c2ccc(Cl)c(Cl)c2)[C@@H]2CNC[C@@H]21 CHEMBL596805 pKi 1.585 nM
CSC[C@H]1[C@@H]2CNC[C@@]21c1ccc(Cl)c(Cl)c1 CHEMBL599241 pKi 1.585 nM
FC(F)(F)COC[C@@H]1[C@H]2CNC[C@]21c1ccc(Cl)c(Cl)c1 CHEMBL597190 pKi 1.585 nM
CNC1CC(c2ccc(Cl)c(Cl)c2)c2ccccc21 CHEMBL296602 pKi 1.585 nM
Cc1ccnn1CC12CNCC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL1818452 pKi 1.585 nM
Cc1cc(C)n(C[C@@]23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)n1 CHEMBL1818454 pKi 1.585 nM
Fc1cc(F)c(F)c(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1F CHEMBL2338053 pIC50 1.585 nM
Clc1cccc(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1Cl CHEMBL2337602 pIC50 1.585 nM
CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 CHEMBL1175 pIC50 1.585 nM
CNCCC(Oc1ccccc1OC)c1ccccc1 CHEMBL295467 Ki 1.6 nM
CNC[C@@H](O)[C@H](c1ccccc1)N1CC(C)(C)c2cccc(F)c21 CHEMBL591928 IC50 1.6 nM
Clc1ccccc1CN(CC1CNC1)c1ccccc1 CHEMBL3331508 IC50 1.6 nM
C#CCN(CC#C)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL402441 IC50 1.7 nM
O=C(NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1)c1ccccc1 CHEMBL4761826 IC50 1.7 nM
COc1cccc2c1C(O)(c1ccc(Cl)cc1)N1CCN=C21 CHEMBL132954 IC50 1.73 nM
COC[C@H]1[C@@H]2CNC[C@@]21c1ccc(Cl)c(Cl)c1 CHEMBL596809 pKi 1.738 nM
COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@H]1c1ccc(C)c(F)c1)N2 CHEMBL391864 Ki 1.78 nM
CC(C)CN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL441358 Ki 1.8 nM
CCOc1ccccc1O[C@H](c1ccccc1)[C@H]1CNCCO1 CHEMBL383921 IC50 1.8 nM
CSc1ccc([C@H]2CN3CCC[C@H]3c3ccccc32)cc1 CHEMBL361259 Ki 1.82 nM
C#Cc1ccc([C@@H]2C[C@H]3CC[C@@H](N3)[C@H]2C(=O)OC)cc1 CHEMBL394158 Ki 1.86 nM
Oc1ccc(C2(O)c3ccccc3C3=NCCCN32)cc1 CHEMBL130668 IC50 1.9 nM
O=c1[nH]c(-c2ccn(C[C@@H]3CNCCO[C@H]3c3ccc(Cl)c(F)c3)c(=O)c2)no1 CHEMBL3819009 IC50 1.9 nM
Clc1ccc([C@]23CNC[C@H]2[C@@H]3COCC2CC2)cc1Cl CHEMBL599639 pKi 1.95 nM
COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@H]1c1ccc(I)cc1)N2 CHEMBL398370 Ki 1.98 nM
CCC(C)OC[C@]1(c2ccc(Cl)c(Cl)c2)[C@@H]2CNC[C@@H]21 CHEMBL598228 pKi 1.995 nM
Clc1ccc([C@]23CNC[C@H]2[C@@H]3COC2CCCCC2)cc1Cl CHEMBL605119 pKi 1.995 nM
CCC[C@H]1[C@@H]2CNC[C@]12c1ccc(Cl)c(Cl)c1 CHEMBL600645 pKi 1.995 nM
COC[C@@]12CNCC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL1173532 pIC50 1.995 nM
CCCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCCN1 CHEMBL1224165 pKi 1.995 nM
Fc1ccc(O[C@@H](c2ccccc2)[C@H]2CCNC2)c(Cl)c1 CHEMBL2338035 pIC50 1.995 nM
Clc1cccc(Cl)c1O[C@H](c1ccccc1)[C@@H]1CCNC1 CHEMBL2337606 pIC50 1.995 nM
Clc1ccc(O[C@@H](c2ccccc2)[C@H]2CCNC2)c(Cl)c1 CHEMBL2337604 pIC50 1.995 nM
Clc1cccc(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1 CHEMBL2337594 pIC50 1.995 nM
COc1ccccc1O[C@H](c1ccccc1)[C@@H]1CCNC1 CHEMBL2337587 pIC50 1.995 nM
CC(C)CN(Cc1ccc(Cl)cc1Cl)C1CCNCC1 CHEMBL207860 Ki 2.0 nM
c1ccc([C@H](Oc2ccccc2C2CC2)[C@@H]2CNCCO2)cc1 CHEMBL476356 Activity 2.0 nM
COc1cccc(F)c1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL522097 Activity 2.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccccc1SC CHEMBL462384 IC50 2.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccc(C)cc1C CHEMBL512044 IC50 2.0 nM
c1ccc(-c2ccccc2OC(c2cccnc2)C2CCNCC2)cc1 CHEMBL562244 IC50 2.0 nM
Fc1ccc(COc2ccc(F)cc2C2CCNCC2)cc1 CHEMBL574008 Ki 2.0 nM
CNCC(O)CCN1c2ccccc2N(c2ccccc2)S1(=O)=O CHEMBL1083393 IC50 2.0 nM
CNC[C@@H](O)CCN1c2ccccc2N(c2ccccc2)S1(=O)=O CHEMBL1083409 IC50 2.0 nM
CNC[C@@H](O)CCN1c2ccccc2N(c2c(F)cccc2F)S1(=O)=O CHEMBL1083429 IC50 2.0 nM
CNC[C@@H](O)CCN1c2ccccc2N(c2cc(F)ccc2F)S1(=O)=O CHEMBL1083118 IC50 2.0 nM
CNCCC(C)N1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1084042 IC50 2.0 nM
CNCC(O)CCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1083083 IC50 2.0 nM
CNCC(=O)CCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1083392 IC50 2.0 nM
OC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593395 IC50 2.0 nM
CCOC(=O)NCCNC(CC(C)C)C1(c2ccc(OCC)cc2)CCC1 CHEMBL3704751 Ki 2.0 nM
CN1Cc2ccccc2C(c2cccc3ccoc23)C1 CHEMBL3323094 Ki 2.0 nM
CN1Cc2ccccc2C(c2ccc3occc3c2)C1 CHEMBL3323089 Ki 2.0 nM
COC[C@H]1[C@@H](c2ccc(Cl)c(Cl)c2)C[C@@H]2CC[C@H]1N2C CHEMBL4226716 IC50 2.0 nM
CNCC[C@@H](Oc1ccccc1C)c1ccccc1 CHEMBL641 Kd 2.03 nM
CSc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL272003 Ki 2.06 nM
OCC1(c2ccc(Cl)c(Cl)c2)CCCNCC1 CHEMBL3593274 IC50 2.1 nM
C=C1CN2C3CC[C@@H]2C[C@H](c2ccc(C)cc2)C13 CHEMBL101905 IC50 2.2 nM
CC(C)CN(Cc1ccc(C(F)(F)F)cc1F)C1CCNCC1 CHEMBL208232 Ki 2.2 nM
C=C1CN2C3CCC2C1C(c1ccc(C)cc1)C3 CHEMBL377785 IC50 2.2 nM
C=CCN(CC=C)C(=O)[C@@]1(c2cccs2)C[C@H]1CN CHEMBL512851 IC50 2.3 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1CCc2cc(C)ccc21 CHEMBL597968 IC50 2.3 nM
CC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL3593402 IC50 2.3 nM
C[C@@H](CCNCCCC(N)=O)CC1(c2ccc(Cl)c(Cl)c2)CCC1 CHEMBL3704754 Ki 2.3 nM
CN1Cc2cc(-c3cccnn3)ccc2C(c2cc3ccccc3o2)C1 CHEMBL3663918 Ki 2.4 nM
COC(=O)C1C2CCC(CC1c1ccc(/C=C\Br)cc1)N2 CHEMBL14531 Ki 2.5 nM
Clc1ccc([C@@]2(COC3CCC3)[C@@H]3CNC[C@@H]32)cc1Cl CHEMBL590472 pKi 2.512 nM
CCCC1(C(=O)c2cc(F)c3[nH]ccc3c2)CCNC1 CHEMBL1224402 pKi 2.512 nM
CC(C)(C)CCC1(C(=O)c2cc3ccccc3s2)CCNC1 CHEMBL1224237 pKi 2.512 nM
CC(C)(C)CCC1(C(=O)c2cc3ccccc3[nH]2)CCNC1 CHEMBL1224238 pKi 2.512 nM
CC(C)CC1(C(=O)c2ccc(N)c(Cl)c2)CCCN1 CHEMBL1224090 pKi 2.512 nM
CC(C)OCC1(C(=O)c2ccc(N)c(Cl)c2)CCCN1 CHEMBL1224091 pKi 2.512 nM
Clc1cc(Cl)c(O[C@@H](c2ccccc2)[C@H]2CCNC2)c(-c2ccccn2)c1 CHEMBL2338055 pIC50 2.512 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1CC(C)(C)c2ccccc21 CHEMBL601880 IC50 2.6 nM
CN1Cc2ccccc2C(c2ccc3[nH]ncc3c2)C1Cl CHEMBL3913012 Ki 2.6 nM
O=C(NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1)C1COCCO1 CHEMBL4792902 IC50 2.6 nM
CCCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL4777709 IC50 2.6 nM
CC(C)(C)CN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL208420 Ki 2.7 nM
C=CCN(CC=C)C(=O)[C@@]1(c2ccsc2)C[C@H]1CN CHEMBL255663 IC50 2.7 nM
CCOc1ccc(C2(C[C@@H](C)CCNCCCC(N)=O)CCC2)cc1 CHEMBL3704757 Ki 2.79 nM
OC1(c2ccccc2)c2ccccc2C2=NCCN21 CHEMBL133902 IC50 2.8 nM
C#CCN(CC=C)C(=O)[C@@]1(c2ccsc2)C[C@H]1CN CHEMBL255450 IC50 2.8 nM
C=CCN(CC)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL427904 IC50 2.9 nM
C=CN(CC)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL401677 IC50 2.9 nM
CN1Cc2cc(CN)ccc2C(c2ccc3sccc3c2)C1 CHEMBL3323178 IC50 2.9 nM
C=C1CN2C3CCC2C1C(c1ccc(Br)cc1)C3 CHEMBL212452 Ki 2.94 nM
CNCCCC1Cc2ccccc2N(c2ccc(C)cc2)C1=O CHEMBL198033 Ki 3.0 nM
Clc1cccc(CN(Cc2ccccn2)[C@H]2CCNC2)c1Cl CHEMBL391806 IC50 3.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1cccc(F)c1C CHEMBL444742 IC50 3.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1ccccc1C(F)(F)F CHEMBL526270 IC50 3.0 nM
c1ccc(CC2(c3ccc4sccc4c3)CCNC2)cc1 CHEMBL486537 Ki 3.0 nM
Brc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL522482 Activity 3.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1cccc(C)c1C CHEMBL461143 IC50 3.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccccc1-c1cccc2ccccc12 CHEMBL510915 IC50 3.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccccc1C CHEMBL507359 IC50 3.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1cccc(F)c1C CHEMBL517423 IC50 3.0 nM
Clc1cccc(OC(c2cccnc2)[C@H]2CCCNC2)c1Cl CHEMBL563030 IC50 3.0 nM
O=C(c1ccccc1Oc1ccccc1)N(c1ccccc1)[C@H]1CCNC1 CHEMBL564935 Ki 3.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccccc1C#N CHEMBL382741 IC50 3.0 nM
Cc1ccc(F)c(Oc2ccccc2C2CCNCC2)c1 CHEMBL583332 Ki 3.0 nM
CNCCCC1Cc2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1204411 IC50 3.0 nM
CNC[C@H](O)CCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1083410 IC50 3.0 nM
CNC[C@H](O)CCN1c2ccccc2N(c2ccccc2)S1(=O)=O CHEMBL1083408 IC50 3.0 nM
CN(C)C[C@]1(c2ccc(Cl)c(Cl)c2)CC[C@@](C)(O)CC1 CHEMBL4226362 IC50 3.0 nM
CNCC[C@H](Oc1cccc(N2CCN(C)c3nc(OC)ccc3C2=O)c1)c1cccs1 CHEMBL4761288 IC50 3.0 nM
Fc1ccc(CN(CC2CCC2)C2CCNCC2)c(C(F)(F)F)c1 CHEMBL207480 Ki 3.1 nM
COC(=O)[C@@H]1C2CCC(C[C@H]1c1ccc(Cl)cc1)N2C CHEMBL375888 Ki 3.1 nM
c1ccc(OC(c2ccc3ccccc3c2)C2CNC2)cc1 CHEMBL2171417 IC50 3.1 nM
FCCc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL466187 Ki 3.14 nM
CC(C)(C)CCC1(C(=O)c2ccc(Cl)c(Cl)c2)CCNC1 CHEMBL1224400 pKi 3.162 nM
CC(C)(C)CCC1(C(=O)c2ccc3ccccc3n2)CCNC1 CHEMBL1224239 pKi 3.162 nM
CCCC1(C(=O)c2ccc3[nH]ccc3c2)CCCN1 CHEMBL1224164 pKi 3.162 nM
Cc1ccn(CC23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)n1 CHEMBL1818451 pKi 3.162 nM
Clc1cc(Cl)cc(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1 CHEMBL2337608 pIC50 3.162 nM
COc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CCNC1 CHEMBL2337589 pIC50 3.162 nM
COC[C@H]1CN[C@@H]2CC[C@@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL4227100 pKi 3.162 nM
CNCCC=C1c2ccccc2CCc2ccccc21 CHEMBL445 Ki 3.184 nM
COc1ccccc1C[C@@](O)(c1ccccc1)[C@@H]1CNCCO1 CHEMBL554800 Ki 3.2 nM
CC(C)CN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL380890 Ki 3.2 nM
C=CCN(CC(=C)F)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL404729 IC50 3.2 nM
CCOC[C@H]1[C@@H](c2ccc(Cl)c(Cl)c2)C[C@@H]2CC[C@H]1N2C CHEMBL4224951 IC50 3.2 nM
COCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL4752093 IC50 3.2 nM
CSc1ccccc1CN(CC(C)C)C1CCNCC1 CHEMBL438059 Ki 3.3 nM
Cc1ccccc1CN(CC(C)C)C1CCNCC1 CHEMBL208067 Ki 3.3 nM
OCC[C@]1(c2ccc(Cl)c(Cl)c2)CCCNC1 CHEMBL2321991 Ki 3.3 nM
CC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(C)c1 CHEMBL3593404 IC50 3.3 nM
[2H]C([2H])([2H])OCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL4741247 IC50 3.3 nM
CCOCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL4745694 IC50 3.3 nM
CC(C)CN(Cc1cc(F)ccc1C(F)(F)F)C1CCNCC1 CHEMBL208252 Ki 3.4 nM
Cc1ccc([C@H]2C[C@@H]3CC[C@H]([C@H]2C=C(Br)Br)N3C)cc1 CHEMBL495464 Ki 3.4 nM
CC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(C)c(Cl)c1 CHEMBL3593405 IC50 3.4 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 3.4 nM
C=CCN(CC=C)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL256557 IC50 3.5 nM
CN1[C@H]2CC[C@@H]1[C@@H](C=C(Br)Br)[C@@H](c1ccc(Cl)cc1)C2 CHEMBL494626 Ki 3.5 nM
CCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL207854 Ki 3.6 nM
FCCCc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL505592 Ki 3.68 nM
O[C@](Cc1ccccc1-c1ccccc1)(c1ccccc1)[C@@H]1CNCCO1 CHEMBL204574 Ki 3.7 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1C[C@H](C)c2ccccc21 CHEMBL592167 IC50 3.7 nM
C[C@@H]1NCCCN(c2ccc3ccccc3c2)C1=O CHEMBL3317704 IC50 3.8 nM
CN1Cc2c(N)cccc2C(c2ccccc2)C1 CHEMBL273575 Ki 3.8 nM
CCCC(c1ccc(Cl)c(Cl)c1)C1CCCCN1 CHEMBL219649 Ki 3.9 nM
C#CCN(CC1CC1)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL404730 IC50 3.9 nM
C=C(F)CN(CCOC)C(=O)[C@@]1(c2ccsc2)C[C@H]1CN CHEMBL257389 IC50 3.9 nM
COCCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL4762373 IC50 3.9 nM
COc1cccc(CN(c2ccc3[nH]ccc3c2)C2CCNCC2)c1 CHEMBL550870 pKi 3.981 nM
Clc1ccc([C@@]2(CCOC3CCC3)[C@@H]3CNC[C@@H]32)cc1Cl CHEMBL611367 pKi 3.981 nM
CCC(C)OCC[C@]1(c2ccc(Cl)c(Cl)c2)[C@@H]2CNC[C@@H]21 CHEMBL596806 pKi 3.981 nM
CCOCC[C@H]1[C@@H]2CNC[C@]12c1ccc(Cl)c(Cl)c1 CHEMBL597608 pKi 3.981 nM
FC(F)(F)COC[C@H]1[C@@H]2CNC[C@@]21c1ccc(Cl)c(Cl)c1 CHEMBL598202 pKi 3.981 nM
Clc1ccc([C@@H]2CCNC[C@@]23CCCOC3)cc1Cl CHEMBL1173607 pKi 3.981 nM
Cc1ccc(C(=O)C2(CCC(C)(C)C)CCNC2)cc1Cl CHEMBL1224399 pKi 3.981 nM
Fc1ccc(F)c(O[C@@H](c2ccccc2)[C@@H]2CCNC2)c1Cl CHEMBL2338051 pIC50 3.981 nM
Fc1ccc(F)c(O[C@H](c2ccccc2)[C@H]2CCNC2)c1Cl CHEMBL2338050 pIC50 3.981 nM
Cc1cc(Cl)ccc1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2338039 pIC50 3.981 nM
Fc1cc(F)cc(O[C@H](c2ccccc2)[C@@H]2CCNC2)c1 CHEMBL2338033 pIC50 3.981 nM
Fc1ccccc1O[C@H](c1ccccc1)[C@@H]1CCNC1 CHEMBL2337598 pIC50 3.981 nM
Clc1ccccc1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2337592 pIC50 3.981 nM
Clc1ccc(C2CCNCC23CCOCC3)cc1Cl CHEMBL4224830 pKi 3.981 nM
Cc1cccc(CN(C2CCOCC2)[C@H]2CCNC2)c1Cl CHEMBL247340 IC50 4.0 nM
C#CCN(CC(=C)F)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL258451 IC50 4.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1c(F)cccc1C(F)(F)F CHEMBL497512 IC50 4.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1c(C)cccc1F CHEMBL497846 IC50 4.0 nM
CCOc1cccc(F)c1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL489773 Activity 4.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1cccc(O)c1C CHEMBL514937 IC50 4.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccc(O)cc1C CHEMBL454770 IC50 4.0 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)n1cc(C)c2ccccc21 CHEMBL576145 IC50 4.0 nM
CN(C)CC1(c2ccc(Cl)c(Cl)c2)CCCCC1 CHEMBL1683874 IC50 4.0 nM
OCC[C@]1(c2cc3ccccc3o2)CCCNC1 CHEMBL2321993 Ki 4.0 nM
CN1Cc2c(N)cccc2[C@H](c2ccccc2)C1 CHEMBL51697 Ki 4.0 nM
N[C@H]1CC[C@H](c2ccc(Cl)c(Cl)c2)c2ccccc21 CHEMBL4227980 IC50 4.0 nM
COc1ccc(C2(O)c3ccccc3C3=NCCCN32)cc1 CHEMBL133043 IC50 4.1 nM
FC(F)(F)c1ccccc1CN(C1CCCC1)C1CCNCC1 CHEMBL208191 Ki 4.1 nM
CCn1c(=O)n([C@@H](c2cccc(F)c2)[C@H](O)CNC)c2c(F)cccc21 CHEMBL560877 IC50 4.1 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)n1c(=O)n(C(C)C)c2cccc(F)c21 CHEMBL551474 IC50 4.1 nM
CNC[C@@H](O)[C@H](c1cc(F)cc(F)c1)N1CC(C)(C)c2ccccc21 CHEMBL600424 IC50 4.1 nM
CN1Cc2cc(-c3cccnn3)ccc2C(c2ccc3ccccc3c2)C1 CHEMBL3897415 Ki 4.1 nM
C#Cc1ccc([C@@H]2CN3CCC[C@@H]3c3ccccc32)cc1 CHEMBL286312 Ki 4.1 nM
CC(C)(O)CN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL209094 Ki 4.2 nM
NC[C@@H]1C[C@@]1(C(=O)N1CCc2ccccc21)c1ccc2c(c1)OCO2 CHEMBL409715 IC50 4.2 nM
NCC1CC1(C(=O)N1CCc2ccccc21)c1ccccc1 CHEMBL260440 IC50 4.4 nM
C#CCN(C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN)C1CC1 CHEMBL257336 IC50 4.4 nM
C=C(F)CN(CC)C(=O)[C@@]1(c2cccs2)C[C@H]1CN CHEMBL469946 IC50 4.4 nM
Cc1ccc(C2CN(C)Cc3ccccc32)cc1F CHEMBL2206526 Ki 4.4 nM
C=CCN(CC=C)C(=O)[C@@]1(c2ccc3c(c2)CCO3)C[C@H]1CN CHEMBL404013 IC50 4.5 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1CCc2ccccc21 CHEMBL610514 IC50 4.6 nM
C=Cc1ccc([C@@H]2C[C@H]3CC[C@@H](N3)[C@H]2C(=O)OC)cc1 CHEMBL394157 Ki 4.67 nM
COc1cccc2c1C1=NCCN1C2(O)c1ccc(Cl)cc1 CHEMBL336940 IC50 4.7 nM
CNCC[C@H](Oc1cccc2cc(O)ccc12)c1cccs1 CHEMBL332098 Ki 4.72 nM
Cc1ccc(CN(CC(C)C)C2CCNCC2)c(C)c1 CHEMBL207374 Ki 4.8 nM
Clc1ccc(C2CNCc3cc(-c4ccc5ncnn5c4)ccc32)cc1Cl CHEMBL3703746 IC50 4.8 nM
CC(C)OCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL4758692 IC50 4.8 nM
C=C1CN2C3CCC2C1C(c1ccc(Cl)cc1)C3 CHEMBL378536 Ki 4.84 nM
COC(=O)[C@@H]1[C@H]2CC[C@H](C[C@H]1c1ccc(C)cc1)N2 CHEMBL235569 Ki 4.88 nM
OC1(c2ccc(Cl)cc2)c2ccccc2C2=NCCCN21 CHEMBL130477 IC50 4.9 nM
CN1Cc2ccccc2C(c2ccc3cnsc3c2)C1 CHEMBL3323107 Ki 4.9 nM
CN(C)Cc1ccccc1Sc1ccccc1N CHEMBL190700 Ki 4.95 nM
CNCCCC1Cc2cc(F)ccc2N(c2ccc(C)cc2)C1=O CHEMBL194781 Ki 5.0 nM
COC(=O)[C@@H]1C2CCC(C[C@@H]1c1ccc(Cl)c(Cl)c1)N2C CHEMBL42553 Ki 5.0 nM
Cc1c(Cl)cccc1CN(C1CCOCC1)[C@H]1CCNC1 CHEMBL247341 IC50 5.0 nM
Clc1cccc(CN(C2CCOCC2)[C@H]2CCNC2)c1Cl CHEMBL245880 IC50 5.0 nM
Clc1cccc(CN(Cc2ccccn2)[C@@H]2CCNC2)c1Cl CHEMBL440230 IC50 5.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1ccccc1C CHEMBL505433 IC50 5.0 nM
N#Cc1c[nH]c2ccc(C3(Cc4ccccc4)CCNC3)cc12 CHEMBL517305 Ki 5.0 nM
c1ccc(CC2(c3ccc4[nH]ncc4c3)CCNC2)cc1 CHEMBL520869 Ki 5.0 nM
CCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 CHEMBL515936 Ki 5.0 nM
CS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 CHEMBL476312 Ki 5.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccccc1Cl CHEMBL446321 IC50 5.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1ccc(F)cc1C CHEMBL506137 IC50 5.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1c(C)cccc1F CHEMBL498904 IC50 5.0 nM
CSc1ccccc1C(=O)N(C1CCCCC1)[C@H]1CCNC1 CHEMBL553395 Ki 5.0 nM
O=C1C(Cc2ccccc2N2CCNCC2)SCCN1c1ccc(Cl)c(Cl)c1 CHEMBL574126 Ki 5.0 nM
CNCCCC1Cc2ccccc2N(c2c(F)cccc2F)S1(=O)=O CHEMBL1204412 IC50 5.0 nM
CNC(C)CCN1c2ccccc2N(c2ccccc2F)S1(=O)=O CHEMBL1085339 IC50 5.0 nM
N#Cc1ccccc1-c1cccc(O[C@@H]2C[C@H]3CC[C@@H](C2)N3)c1 CHEMBL1644608 IC50 5.0 nM
O=S1(=O)N(CC[C@@H]2CNCCO2)c2ccccc2N1c1ccccc1 CHEMBL1830879 IC50 5.0 nM
O=S1(=O)N(CC[C@@H]2CNCCO2)c2ccccc2N1c1ccccc1F CHEMBL1830885 IC50 5.0 nM
O=S1(=O)N(CCC2CNCCO2)c2c(F)cccc2N1c1ccccc1F CHEMBL1828653 IC50 5.0 nM
Cc1ccc2c(c1)CN(C)CC2c1cccc(Cl)c1 CHEMBL2206507 Ki 5.0 nM
COc1ccc2c(c1)CN(C)CC2c1ccc2sccc2c1 CHEMBL3323174 IC50 5.0 nM
CNCCC(Oc1ccccc1OC)c1ccccc1 CHEMBL1256695 IC50 5.0 nM
CCOc1ccccc1O[C@H](c1ccccc1)[C@H]1CNCCO1 CHEMBL2105282 IC50 5.0 nM
CC(C)(C)CCC1(C(=O)c2ccc(N)c(Cl)c2)CCNC1 CHEMBL1224317 pKi 5.012 nM
Cc1cc(Cl)cc(-c2ccccn2)c1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2338054 pIC50 5.012 nM
COc1cc([N+](=O)[O-])ccc1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2338038 pIC50 5.012 nM
Clc1cc(Cl)cc(O[C@@H](c2ccccc2)[C@H]2CCNC2)c1 CHEMBL2337607 pIC50 5.012 nM
Clc1ccc(O[C@H](c2ccccc2)[C@@H]2CCNC2)cc1 CHEMBL2337597 pIC50 5.012 nM
COc1ccccc1O[C@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2337588 pIC50 5.012 nM
CCCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL207023 Ki 5.1 nM
[3H]C([3H])([3H])NCCC(Oc1ccccc1OC)c1ccccc1 CHEMBL1628648 Kd 5.1 nM
OCC[C@]1(c2ccc(Cl)c(Cl)c2)CCCCNC1 CHEMBL2326695 Ki 5.1 nM
OC1(c2ccc3ccccc3c2)c2ccc3ccccc3c2C2=NCCN21 CHEMBL340281 Ki 5.2 nM
CCOc1ccccc1C[C@@](O)(c1ccccc1)[C@@H]1CNCCO1 CHEMBL208993 Ki 5.2 nM
C=C(F)CN(CC)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL405613 IC50 5.2 nM
CN1Cc2ccccc2C(c2ccc3ccoc3c2)C1 CHEMBL3323090 IC50 5.2 nM
OC1(c2ccc(Cl)cc2)c2ccc3ccccc3c2C2=NCCCN21 CHEMBL334577 Ki 5.3 nM
O=C(NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1)C1CCCO1 CHEMBL4754191 IC50 5.3 nM
COCCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL207755 Ki 5.4 nM
CCOc1ccc(C2(CC(C)CCNCCCC(N)=O)CCC2)cc1 CHEMBL3704756 Ki 5.49 nM
CC(C)CN(Cc1cc(Cl)ccc1Cl)C1CCNCC1 CHEMBL208535 Ki 5.5 nM
CN1Cc2cc(O)ccc2C(c2ccc3sccc3c2)C1 CHEMBL3323175 IC50 5.5 nM
Clc1ccc(C(Oc2ccccc2)C2CNC2)cc1Cl CHEMBL2219884 IC50 5.5 nM
COC(=O)C1C2CCC(CC1c1ccc(C=C(Br)Br)cc1)N2 CHEMBL14257 Ki 5.6 nM
C=CCN(CC)C(=O)[C@@]1(c2ccsc2)C[C@H]1CN CHEMBL257602 IC50 5.6 nM
OC[C@@]1(c2ccc(Cl)c(Cl)c2)CCNCCO1 CHEMBL3593392 IC50 5.6 nM
CNC[C@@H](O)[C@H](c1ccccc1)N1CC(C)(C)c2ccccc21 CHEMBL600220 IC50 5.7 nM
CCOc1ccc(C2(C(CC(C)C)NCCOC(=O)CC)CCC2)cc1 CHEMBL3704749 Ki 5.7 nM
NC[C@@H]1C[C@@]1(C(=O)N1CCOc2ccccc21)c1ccc2c(c1)OCO2 CHEMBL411655 IC50 5.8 nM
Cc1ccc2c(c1)CN(C)CC2c1cc(F)cc(F)c1 CHEMBL2206508 Ki 5.8 nM
CC(=O)NCC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593401 IC50 5.8 nM
OC[C@H]1CNCCO[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593396 IC50 5.8 nM
CN1Cc2ccccc2C(c2ccc3[nH]ccc3c2)C1 CHEMBL3323101 Ki 5.8 nM
C=C1CN2C3CCC2C1C(c1ccc(I)cc1)C3 CHEMBL380383 Ki 5.87 nM
C#CCN(CC)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL260131 IC50 5.9 nM
CNCCCC1Cc2cc(Cl)ccc2N(c2ccc(C)cc2)C1=O CHEMBL373233 Ki 6.0 nM
FC(F)(F)c1ccccc1CN(CC1CC1)C1CCNCC1 CHEMBL377882 Ki 6.0 nM
CC(C)CN(Cc1c(F)cccc1C(F)(F)F)C1CCNCC1 CHEMBL379699 Ki 6.0 nM
COc1cc(F)ccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL260258 Ki 6.0 nM
C#CCN(CC#C)C(=O)[C@@]1(c2cccs2)C[C@H]1CN CHEMBL513248 IC50 6.0 nM
CNCC[C@H](c1cc(F)cc(F)c1)N1C(=O)C(C)(C)c2cccc(F)c21 CHEMBL446809 IC50 6.0 nM
Fc1cccc(F)c1O[C@@H](c1ccccn1)[C@@H]1CNCCO1 CHEMBL518748 Activity 6.0 nM
CC(C)C(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 CHEMBL476116 Ki 6.0 nM
CNCC[C@H](c1ccccc1)n1c(=O)n(-c2ccccc2F)c2cccc(F)c21 CHEMBL511827 IC50 6.0 nM
Clc1cccc(OC(c2cccnc2)C2CCNCC2)c1Cl CHEMBL559456 IC50 6.0 nM
O=C(c1ccccc1C(F)(F)F)N(CC1CCC1)[C@H]1CCNC1 CHEMBL552338 Ki 6.0 nM
CCSc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 CHEMBL556539 Ki 6.0 nM
Fc1ccc(COc2ccc(Cl)cc2C2CCNCC2)cc1 CHEMBL574629 Ki 6.0 nM
CNC[C@H](O)CCN1c2ccccc2N(c2c(F)cccc2F)S1(=O)=O CHEMBL1083428 IC50 6.0 nM
CCN(CC)CC1(c2ccc(Cl)c(Cl)c2)CCCCC1 CHEMBL1683876 IC50 6.0 nM
OC[C@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593394 IC50 6.0 nM
c1ccc2cc([C@]34CNCC3C4)ccc2c1 CHEMBL4227573 IC50 6.0 nM
CCC(CC)CN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL378498 Ki 6.1 nM
Fc1ccc(CN(CC2CC2)C2CCNCC2)c(C(F)(F)F)c1 CHEMBL207214 Ki 6.1 nM
CC(C)(C#N)CCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL207634 Ki 6.2 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1CC(C)c2ccccc21 CHEMBL599609 IC50 6.2 nM
CCN(CC)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL264678 IC50 6.3 nM
Cc1cc([C@H]2[C@@H](c3ccc(Cl)c(C)c3)C[C@@H]3CC[C@H]2N3C)on1 CHEMBL1812747 IC50 6.3 nM
N#Cc1ccccc1CN(c1ccc2[nH]ccc2c1)C1CCNCC1 CHEMBL550469 pKi 6.31 nM
Fc1cc(N2CCNCC2Cc2ccccc2)cc2cc[nH]c12 CHEMBL1170211 pKi 6.31 nM
CC(C)(C)CCC1(C(=O)c2ccc3[nH]ncc3c2)CCNC1 CHEMBL1224319 pKi 6.31 nM
Cc1cnc([C@@]23CNCC[C@]2(c2ccc(Cl)c(Cl)c2)C3)o1 CHEMBL1818443 pKi 6.31 nM
COC[C@@H]1CN[C@@H]2CC[C@@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL4226867 pKi 6.31 nM
CCn1c(=O)n([C@@H](c2cccc(F)c2)[C@H](O)CNC)c2ccccc21 CHEMBL564229 IC50 6.4 nM
CCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL208121 Ki 6.5 nM
Fc1ccc(CN(CC2CC2)C2CCNCC2)c(C(F)(F)F)c1 CHEMBL207067 Ki 6.5 nM
NC[C@@H]1C[C@@]1(C(=O)N1CCc2ccccc2C1)c1ccc2c(c1)OCO2 CHEMBL264430 IC50 6.5 nM
COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@H]1c1ccc(Cl)c(C)c1)N2C CHEMBL1812749 IC50 6.5 nM
NCCc1ccc(O)c(O)c1 CHEMBL59 IC50 6.63 nM
CN1Cc2ccccc2C(c2ccc3cc[nH]c3c2)C1 CHEMBL3323102 Ki 6.7 nM
COCCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL208178 Ki 6.8 nM
Fc1cccc(F)c1-n1nc(OC2CCNCC2)c2ccccc21 CHEMBL1836644 Ki 6.8 nM
CN1Cc2ccccc2C(c2ccc3ncsc3c2)C1 CHEMBL3323106 IC50 6.8 nM
Clc1ccc(C2c3ccccc3C3=NCCN32)cc1 CHEMBL336613 IC50 6.9 nM
COc1ccc(O[C@@H](CC(C)C)[C@H]2CCNC2)c(C)n1 CHEMBL2386162 IC50 6.9 nM
CCCC1(CCCNC)Cc2ccccc2N(c2ccccc2)C1=O CHEMBL198960 Ki 7.0 nM
CN(C)Cc1cc(OCCCO)ccc1Sc1ccccc1N CHEMBL241647 Ki 7.0 nM
Cc1ccccc1CN(C1CCOCC1)[C@H]1CCNC1 CHEMBL397392 IC50 7.0 nM
Cc1cccc(CN(C2CCOCC2)[C@H]2CCNC2)c1C CHEMBL247733 IC50 7.0 nM
C=CCN(CC=C)C(=O)[C@@]1(c2ccc3c(c2)OCO3)C[C@H]1CN CHEMBL259694 IC50 7.0 nM
CCc1ccccc1O[C@H]1c2ccccc2OC[C@H]1CNC CHEMBL525238 IC50 7.0 nM
CNC[C@@H]1CCc2ccccc2[C@@H]1Oc1ccccc1C CHEMBL525375 IC50 7.0 nM
Fc1ccc(CC2(c3ccc4[nH]ccc4c3)CCNC2)cc1 CHEMBL513258 Ki 7.0 nM
CNCC[C@H](c1cccc(Cl)c1)N1C(=O)C(C)(C)c2cccc(F)c21 CHEMBL475937 IC50 7.0 nM
CNCC[C@H](c1ccccc1)N1C(=O)C(C)(C)c2ccccc21 CHEMBL513912 IC50 7.0 nM
Fc1cccc(F)c1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL522296 Activity 7.0 nM
Fc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL499576 Activity 7.0 nM
CCOc1ccccc1O[C@@H](c1ccccn1)[C@@H]1CNCCO1 CHEMBL514208 Activity 7.0 nM
CCCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 CHEMBL476313 Ki 7.0 nM
CNC[C@@H]1Cc2ccccc2[C@@H]1Oc1ccccc1C CHEMBL455447 IC50 7.0 nM
CNC[C@]1(O)Cc2ccccc2[C@@H]1Oc1cc(F)ccc1C CHEMBL516507 IC50 7.0 nM
O=C(c1ccccc1Oc1ccccc1)N(CC1CCC1)[C@H]1CCNC1 CHEMBL549584 Ki 7.0 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)n1ccc2cccc(F)c21 CHEMBL575132 IC50 7.0 nM
CN(C)CC1(c2ccc3ccccc3c2)CCCCC1 CHEMBL1683902 IC50 7.0 nM
CC(N(C)C)C1(c2ccc(Cl)c(Cl)c2)CCCCC1 CHEMBL1684047 IC50 7.0 nM
O=S1(=O)N(CCC2CNCCO2)c2ccccc2N1c1ccccc1 CHEMBL1830877 IC50 7.0 nM
O=S1(=O)N(CCC2CNCCO2)c2cccc(F)c2N1c1ccccc1F CHEMBL1830892 IC50 7.0 nM
CCNc1ncc2c(n1)N(C)CCN(c1ccc(COC(CCNC)c3ccccc3)cc1)C2=O CHEMBL4790212 IC50 7.0 nM
CNCC[C@H](Oc1cccc(N2CCN(C)c3nc(N)ncc3C2=O)c1)c1cccs1 CHEMBL4745144 IC50 7.0 nM
CC(C)CN(Cc1ccccc1OC(F)(F)F)C1CCNCC1 CHEMBL207914 Ki 7.1 nM
CCN(CC1CC1)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL408016 IC50 7.1 nM
C=CCN(CC)C(=O)[C@@]1(c2ccc3c(c2)OCO3)C[C@H]1CN CHEMBL406789 IC50 7.1 nM
C[C@H](N)Cc1ccccc1 CHEMBL612 EC50 7.1 nM
Cc1ccc2c(c1)CN(C)C[C@H]2c1ccc(F)cc1 CHEMBL2206509 Ki 7.1 nM
CN1Cc2ccccc2C(c2ccc(Cl)c(F)c2)C1 CHEMBL2206525 Ki 7.2 nM
COc1ccc2c(c1)CN(C)CC2c1cccc(C)c1 CHEMBL2206532 Ki 7.3 nM
COC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2 CHEMBL14613 Ki 7.5 nM
CN(C)Cc1cc(OCCF)ccc1Sc1ccccc1N CHEMBL238867 Ki 7.5 nM
CCCC(C(=O)c1ccc(O)c(O)c1)N1CCCC1 CHEMBL202846 IC50 7.6 nM
C#CCN(CC#C)C(=O)[C@@]1(c2ccc3c(c2)OCO3)C[C@H]1CN CHEMBL408384 IC50 7.6 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1CCc2cc(Cl)ccc21 CHEMBL598168 IC50 7.6 nM
Cc1ccc2c(c1)CN(C)CC2c1ccc(F)cc1 CHEMBL3323088 Ki 7.6 nM
CN1Cc2cc(N3CCOCC3)ccc2C(c2ccc3sccc3c2)C1 CHEMBL3323182 Ki 7.6 nM
CC(C)Oc1ccccc1C[C@@](O)(c1ccccc1)[C@@H]1CNCCO1 CHEMBL382034 Ki 7.7 nM
CCC1NCCCN(c2ccc(Cl)c(Cl)c2)C1=O CHEMBL3317701 IC50 7.7 nM
CNC[C@@H](O)[C@H](c1ccccc1)n1c(=O)n(C(C)C)c2cccc(F)c21 CHEMBL551473 IC50 7.8 nM
CN1Cc2ccccc2C(c2cccc3ccsc23)C1 CHEMBL3323100 IC50 7.8 nM
c1ccc(CN(c2ccc3[nH]ccc3c2)C2CCNCC2)cc1 CHEMBL560535 pKi 7.943 nM
CCOCC[C@]1(c2ccc(Cl)c(Cl)c2)[C@@H]2CNC[C@@H]21 CHEMBL609023 pKi 7.943 nM
COCC[C@]1(c2ccc(Cl)c(Cl)c2)[C@@H]2CNC[C@@H]21 CHEMBL602323 pKi 7.943 nM
Clc1ccc([C@@]2(COCC3CC3)[C@@H]3CNC[C@@H]32)cc1Cl CHEMBL598644 pKi 7.943 nM
OCC[C@H]1[C@@H]2CNC[C@]12c1ccc(Cl)c(Cl)c1 CHEMBL598216 pKi 7.943 nM
c1ccc(CC2CNCCN2c2ccc3[nH]ccc3c2)cc1 CHEMBL1171391 pKi 7.943 nM
CCOC(=O)[C@@]12CNCC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL1173751 pKi 7.943 nM
CCOC[C@@]12CNCC[C@]1(c1ccc(Cl)c(Cl)c1)C2 CHEMBL1173533 pKi 7.943 nM
O=C(c1cc(F)c2[nH]ccc2c1)C1(Cc2ccccc2)CCNC1 CHEMBL1224563 pKi 7.943 nM
CC(C)(C)CCC1(C(=O)c2cc(Cl)c(Cl)s2)CCNC1 CHEMBL1224241 pKi 7.943 nM
CCCC1(C(=O)c2ccc(N)c(Cl)c2)CCCN1 CHEMBL1224089 pKi 7.943 nM
CC(C)CC1(C(=O)c2ccc3[nH]ncc3c2)CCCN1 CHEMBL1224093 pKi 7.943 nM
CC(C)(C)CCC1(C(=O)c2ccc3[nH]ncc3c2)CCCN1 CHEMBL1224094 pKi 7.943 nM
O=C(c1ccc2[nH]ccc2c1)C1(Cc2ccccc2)CCCN1 CHEMBL1224160 pKi 7.943 nM
Fc1ccc(O[C@@H](c2ccccc2)[C@H]2CCNC2)c(F)c1 CHEMBL2338031 pIC50 7.943 nM
Cc1ccccc1O[C@@H](c1ccccc1)[C@H]1CCNC1 CHEMBL2337590 pIC50 7.943 nM
CNCCCC1Cc2ccccc2N(c2ccccc2)C1=O CHEMBL196365 Ki 8.0 nM
CCCCC1(CCCNC)Cc2ccccc2N(c2ccc(C)cc2)C1=O CHEMBL196110 Ki 8.0 nM
Cc1cccc(CN(Cc2ccccn2)[C@@H]2CCNC2)c1C CHEMBL392016 IC50 8.0 nM
COc1cc(Cl)ccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1 CHEMBL260259 Ki 8.0 nM
CCc1cccc(F)c1O[C@H]1c2ccccc2CO[C@H]1CNC CHEMBL526825 IC50 8.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1ccc(O)cc1C CHEMBL524313 IC50 8.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1ccccc1Cl CHEMBL448375 IC50 8.0 nM
c1ccc(CC2(c3ccc4[nH]ccc4c3)CCNC2)nc1 CHEMBL456654 Ki 8.0 nM
CN[C@H]1Cc2ccccc2[C@H](Oc2ccccc2C)C1 CHEMBL486045 IC50 8.0 nM
CN(C)S(=O)(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 CHEMBL514232 Ki 8.0 nM
CCOC(=O)N(Cc1ccccc1-c1ccccc1)[C@H]1CCNC1 CHEMBL478834 Ki 8.0 nM
Clc1cccc(OC(c2ccncc2)C2CCNCC2)c1Cl CHEMBL550779 IC50 8.0 nM
CSc1ccccc1C(=O)N(CC1CCC1)[C@H]1CCNC1 CHEMBL564059 Ki 8.0 nM
CC(C)CN(C(=O)c1ccccc1Oc1ccccc1)[C@H]1CCNC1 CHEMBL558651 Ki 8.0 nM
CNC[C@@H](O)CCN1c2ccccc2N(c2ccccc2Cl)S1(=O)=O CHEMBL1086035 IC50 8.0 nM
O=S1(=O)N(CCC2CNCCO2)c2cc(F)ccc2N1c1ccccc1F CHEMBL1830890 IC50 8.0 nM
CC1NCCCN(c2ccc(Cl)c(Cl)c2)C1=O CHEMBL3317700 IC50 8.0 nM
C=C(F)CN(C)C(=O)[C@@]1(c2ccc3c(c2)OCCO3)C[C@H]1CN CHEMBL257335 IC50 8.1 nM
CN1Cc2cc(-c3cccnn3)ccc2C(c2cc3ccccc3s2)C1 CHEMBL3663912 Ki 8.1 nM
CC(CCNCCCC(N)=O)CC1(c2ccc(Cl)c(Cl)c2)CCC1 CHEMBL3704753 Ki 8.1 nM
COC(=O)C1C(c2ccc(Cl)cc2)CC2CCC1N2C CHEMBL306208 IC50 8.2 nM
C#CCN(CC#C)C(=O)[C@@]1(c2ccsc2)C[C@H]1CN CHEMBL257388 IC50 8.2 nM
CNC[C@@H](O)CN1c2ccccc2CCc2ccccc21 CHEMBL223058 Ki 8.29 nM
COCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL382248 Ki 8.3 nM
CCCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL426316 Ki 8.3 nM
NC[C@@H]1C[C@@]1(C(=O)N1CCc2ccccc2C1)c1ccsc1 CHEMBL404027 IC50 8.3 nM
CN1Cc2cc(N3CCOCC3)ccc2[C@@H](c2ccc3sccc3c2)C1 CHEMBL3323181 IC50 8.3 nM
NCC1CC1(C(=O)C1NCCc2ccccc21)c1ccccc1 CHEMBL256667 IC50 8.4 nM
CN1C2CCC1[C@@H](C(=O)OCc1cn(CCCCCCOC(=O)[C@H]3C4CCC(C[C@@H]3c3ccc(Cl)cc3)N4C)nn1)[C@@H](c1ccc(Cl)cc1)C2 CHEMBL596001 Ki 8.5 nM
CNC[C@@H](O)[C@H](c1cccc(F)c1)N1C[C@@H](C)c2ccccc21 CHEMBL599813 IC50 8.5 nM
OC[C@@H]1CNCCO[C@@H]1c1ccc(Cl)c(Cl)c1 CHEMBL3593393 IC50 8.5 nM
C=CCN(C(=O)[C@@]1(c2ccsc2)C[C@H]1CN)C1CC1 CHEMBL255449 IC50 8.7 nM
CCSCC(c1ccc(Cl)c(Cl)c1)C1CCNCC1 CHEMBL2407320 IC50 8.7 nM
CCOc1ccccc1CC(c1ccccc1)N1CCCNCC1 CHEMBL214003 IC50 8.8 nM
CN1Cc2cc(-c3ccc(N)nn3)ccc2[C@H](c2ccc3ccccc3c2)C1 CHEMBL2364614 IC50 8.8 nM
CN1Cc2c(N)cccc2C(c2ccc(Cl)c(Cl)c2)C1 CHEMBL4226242 Ki 8.8 nM
COC(C)C(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(F)c1 CHEMBL4762043 IC50 8.8 nM
CNCCCC1(C)Cc2ccccc2N(c2ccc(C)cc2)C1=O CHEMBL198176 Ki 9.0 nM
CC(C)CC(c1ccc(Cl)c(Cl)c1)C1CCCCN1 CHEMBL218999 IC50 9.0 nM
FC(F)(F)c1ccccc1CN(C1CCOCC1)[C@H]1CCNC1 CHEMBL442272 IC50 9.0 nM
Clc1cccc(CN(CC2CC2)[C@H]2CCNC2)c1Cl CHEMBL246920 IC50 9.0 nM
COc1cc(Cl)ccc1O[C@@H](c1cccc(F)c1)[C@@H]1CNCCO1 CHEMBL264159 Ki 9.0 nM
CNC[C@@H]1OCc2ccccc2[C@@H]1Oc1cccc(Cl)c1C CHEMBL497679 IC50 9.0 nM
CCCCC1(c2ccc3[nH]ccc3c2)CCNC1 CHEMBL463585 Ki 9.0 nM
NC(=O)c1cc2cc(C3(Cc4ccccc4)CCNC3)ccc2[nH]1 CHEMBL457931 Ki 9.0 nM
Fc1cccc(F)c1O[C@@H](c1ncco1)[C@@H]1CNCCO1 CHEMBL491810 Activity 9.0 nM
CNCC[C@H](c1ccccc1)n1c(=O)n(-c2ccccc2)c2ccccc21 CHEMBL471519 IC50 9.0 nM
Clc1cccc(OC(c2cccnc2)[C@@H]2CCCNC2)c1Cl CHEMBL549825 IC50 9.0 nM
Clc1cccc(OC(c2ccccn2)[C@@H]2CCNC2)c1Cl CHEMBL551573 IC50 9.0 nM
CSc1ccccc1C(=O)N(C1CCCC1)[C@H]1CCNC1 CHEMBL549510 Ki 9.0 nM
CCN(C(=O)c1ccccc1Oc1ccccc1)[C@H]1CCNC1 CHEMBL563117 Ki 9.0 nM
Fc1cccc(C2CCNCC2)c1OCc1ccccc1 CHEMBL583750 Ki 9.0 nM
Fc1cccc(OCc2ccccc2)c1C1CCNCC1 CHEMBL575930 Ki 9.0 nM
CNC[C@@H](O)[C@H](c1ccccc1)n1cc(C)c2ccccc21 CHEMBL609883 Ki 9.0 nM
Fc1cccc(Cl)c1Oc1ncccc1C1CCNCC1 CHEMBL597134 EC50 9.0 nM
O=S1(=O)N(CCC(O)CNC2CC2)c2ccccc2N1c1ccccc1 CHEMBL1084291 IC50 9.0 nM
N#Cc1ccccc1-c1cccc(O[C@@H]2C[C@H]3CC[C@@H](C2)N3)n1 CHEMBL1644609 IC50 9.0 nM
CCN(C)CC1(c2ccc(Cl)c(Cl)c2)CCCCC1 CHEMBL1683875 IC50 9.0 nM
CCC[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(Cl)c1 CHEMBL1173597 IC50 9.0 nM
O=S1(=O)N(CC[C@H]2CNCCO2)c2ccccc2N1c1ccccc1 CHEMBL1830878 IC50 9.0 nM
COc1ccc2c(c1)CN(C)CC2c1ccc(F)c(F)c1 CHEMBL2206531 Ki 9.0 nM
CNCC[C@H](Oc1cccc(N2CCN(C)c3ncncc3C2=O)c1)c1cccs1 CHEMBL4740331 IC50 9.0 nM
CCC1NCCCN(c2ccc3ccccc3c2)C1=O CHEMBL3317703 IC50 9.2 nM
CSCC(c1ccc(Cl)c(Cl)c1)C1CCNCC1 CHEMBL2407319 IC50 9.3 nM
CCCC(C(=O)c1cccc(C)c1)N1CCCC1 CHEMBL204254 IC50 9.4 nM
NC[C@@H]1C[C@@]1(C(=O)N1CCc2sccc2C1)c1ccc2c(c1)OCO2 CHEMBL410015 IC50 9.4 nM
CCOCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL377574 Ki 9.6 nM
CC(C)OCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 CHEMBL208070 Ki 9.7 nM
CNC[C@@H](O)[C@H](c1ccccc1)N1CCc2ccccc21 CHEMBL599608 IC50 9.7 nM
FC(F)(F)CCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 CHEMBL377678 Ki 9.8 nM
Fc1cc2c(cc1-c1ccc(OC(F)F)nn1)CNCC2c1ccc(Cl)c(Cl)c1 CHEMBL3703742 IC50 9.8 nM