Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C)(C)CC1 CHEMBL3903549 IC50 0.9 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CCC(C)CO1 CHEMBL3949800 IC50 1.4 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@@H]1CC[C@@H](C)CO1 CHEMBL3948610 IC50 1.4 nM
CCC1CC=C(c2onc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)CC1 CHEMBL3918128 IC50 1.8 nM
CCC1CC(C)CC=C1c1onc(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)c1C CHEMBL3908757 IC50 2.1 nM
Cc1c(NC(=O)c2noc3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(C2CCCCC2)n1C CHEMBL4584197 IC50 2.2 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC2(CCCC2)CC1 CHEMBL3979914 IC50 2.5 nM
Cc1c(NC(=O)c2noc3c2CCSc2cc(OC(F)(F)F)ccc2-3)c(=O)n(C2CCCCC2)n1C CHEMBL4559578 IC50 2.6 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C(C)C)CC1 CHEMBL3945602 IC50 2.8 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C(C)(C)C)CC1 CHEMBL3959606 IC50 3.2 nM
Cc1c(NC(=O)c2noc3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(-c2c(Cl)cccc2Cl)n1C CHEMBL4475920 IC50 4.5 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CCC(C)(C)CC1 CHEMBL3922163 IC50 5.7 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)noc1-2 CHEMBL4441459 IC50 5.9 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C)CC1 CHEMBL3923152 IC50 6.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C)(C)C1 CHEMBL3948012 IC50 6.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCCCCC1 CHEMBL3963970 IC50 8.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)noc1-c1ccc(C2CC2)cc1Cl CHEMBL5413507 IC50 11.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCCCC1(C)C CHEMBL3936702 IC50 14.0 nM
Cc1c(NC(=O)c2noc3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(-c2ccccc2F)n1C CHEMBL4473531 IC50 17.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1CCC(C)(C)C CHEMBL3896562 IC50 19.0 nM
Cc1c(NC(=O)c2noc3c2CCCc2cc(CC(C)C)ccc2-3)c(=O)n(-c2ccccc2Cl)n1C CHEMBL4468431 IC50 22.5 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CCC(C)(C)C1 CHEMBL3971227 IC50 23.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)noc1-c1ccc(Cl)cc1Cl CHEMBL5440935 IC50 29.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(C4CCCC4)c3=O)noc1-2 CHEMBL4583928 IC50 29.2 nM
Cc1c(NC(=O)c2noc3c2CCSc2cc(OC(F)(F)F)ccc2-3)c(=O)n(-c2ccccc2F)n1C CHEMBL4460342 IC50 31.5 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(C(F)(F)F)CC1 CHEMBL3937559 IC50 33.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CCCC(C(C)(C)C)O1 CHEMBL3939778 IC50 37.0 nM
Cc1c(C(=O)O)noc1-c1ccc(C2CC2)cc1Cl CHEMBL5405373 EC50 40.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1/C=C\C(C)(C)C CHEMBL3977353 IC50 46.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CCCCC1 CHEMBL3936863 IC50 50.0 nM
Cc1c(NC(=O)c2nnn3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(C2CCCCC2)n1C CHEMBL3975128 IC50 55.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1/C=C/C(C)(C)C CHEMBL3906702 IC50 58.0 nM
Cc1c(NC(=O)c2noc3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(Cc2ccccc2F)n1C CHEMBL4466006 IC50 58.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC2(CCCO2)CC1 CHEMBL3942689 IC50 64.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@H]1OC[C@H](C(C)(C)C)O1 CHEMBL4113496 IC50 74.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@@H]1OC[C@H](C(C)(C)C)O1 CHEMBL4111123 IC50 75.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CC=CC(C(C)C)O1 CHEMBL3933097 IC50 91.0 nM
COc1ccc2c(c1)CCCCc1c(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)noc1-2 CHEMBL4585952 IC50 91.8 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(C2CC2)cc1Cl CHEMBL3933261 IC50 92.0 nM
[2H]C([2H])([2H])n1c(C)c(NC(=O)c2nnn(-c3ccc(C4CC4)cc3Cl)c2C)c(=O)n1C1CCCCC1 CHEMBL4461423 IC50 98.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC2(CCOC2)CC1 CHEMBL3980364 IC50 100.0 nM
CO[C@@H]1C[C@@H](c2onc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)O[C@@H](C(C)(C)C)C1 CHEMBL3953839 IC50 100.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccccc4Cl)c3=O)noc1-2 CHEMBL4462198 IC50 125.0 nM
COc1ccc2c(c1)CCCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccccc4F)c3=O)noc1-2 CHEMBL4547904 IC50 132.5 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CC(C(C)(C)Br)CO1 CHEMBL3924296 IC50 160.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@@H]1OC[C@@H](C(C)(C)C)O1 CHEMBL3897219 IC50 160.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@@H]1OCC(C)(C)O[C@H]1C CHEMBL3938251 IC50 180.0 nM
COc1ccc(-c2onc(C(=O)Nc3c(C)n(C)n(-c4ccccc4F)c3=O)c2C)c(C)c1 CHEMBL5421627 IC50 180.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)noc1-c1ccc(Cl)cc1 CHEMBL5436232 IC50 180.0 nM
Cc1c(NC(=O)c2noc3c2CCCc2cc(OC(F)(F)F)ccc2-3)c(=O)n(-c2ccccc2)n1C CHEMBL4533744 IC50 200.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccccc4F)c3=O)noc1-2 CHEMBL5433058 IC50 200.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(Cl)cc1C1CC1 CHEMBL3981733 IC50 230.0 nM
Cc1c(NC(=O)c2noc3c2CCc2cc(CC(C)C)ccc2-3)c(=O)n(-c2ccccc2)n1C CHEMBL4532439 IC50 240.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@@H]1C[C@@H](C(C)C)CO1 CHEMBL3965072 IC50 250.0 nM
CCc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccc(F)cc4)c3=O)noc1-2 CHEMBL4446476 IC50 272.5 nM
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)noc1-c1cc(Cl)ccc1Cl CHEMBL5398156 IC50 280.0 nM
CO[C@H]1C[C@@H](c2onc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)O[C@@H](C(C)(C)C)C1 CHEMBL3966224 IC50 290.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCC3)c2=O)noc1[C@@H]1CCC[C@H](C(C)(C)C)O1 CHEMBL3945107 IC50 290.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCC(OC(C)C)CC1 CHEMBL3956674 IC50 310.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CC(C(C)C)CO1 CHEMBL3936144 IC50 340.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@H]1C[C@H](C(C)C)CO1 CHEMBL3928794 IC50 350.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)noc1-2 CHEMBL5430940 IC50 400.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccc(F)cc4)c3=O)noc1-2 CHEMBL4540707 IC50 410.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CCC2(CC1)OCCO2 CHEMBL3977920 IC50 420.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@@H]1CC[C@H](C)CO1 CHEMBL3967213 IC50 420.0 nM
COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)c(Cl)c1 CHEMBL3929850 IC50 440.0 nM
Cc1c(NC(=O)c2noc3c2CC2C(c4ccccc4-3)C2(Cl)Cl)c(=O)n(-c2ccccc2)n1C CHEMBL4522525 IC50 462.5 nM
CC1=CCC(c2onc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)OC1 CHEMBL3911739 IC50 490.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4ccc(C)cc4C)c3=O)noc1-2 CHEMBL4439888 IC50 495.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(OC(F)(F)F)cc1Cl CHEMBL3923243 IC50 550.0 nM
CCc1ccc2c(c1)CCc1c(C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)noc1-2 CHEMBL4465535 IC50 568.3 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(Cl)cc1Cl CHEMBL3969407 IC50 570.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1OCC(C)(C)CO1 CHEMBL3903305 IC50 580.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCC3)c2=O)noc1[C@H]1CCC[C@@H](C(C)(C)C)O1 CHEMBL3977739 IC50 630.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1CC(Br)C(C)CO1 CHEMBL3978863 IC50 630.0 nM
COC1CC(c2onc(C(=O)Nc3c(C)n(C)n(C4CCCC4)c3=O)c2C)OC(C(C)(C)C)C1 CHEMBL4543791 IC50 640.0 nM
Cc1c(NC(=O)c2noc3c2CCCCc2ccccc2-3)c(=O)n(-c2ccccc2)n1C CHEMBL4592708 IC50 657.5 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(-c4cccc(Cl)c4)c3=O)noc1-2 CHEMBL4566754 IC50 660.0 nM
CCn1c(C)c(NC(=O)c2noc3c2CCCc2cc(OC)ccc2-3)c(=O)n1-c1ccccc1Cl CHEMBL4532915 IC50 680.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C)n(C)n(Cc4ccccc4)c3=O)noc1-2 CHEMBL4462646 IC50 695.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)noc1-c1ccc(Cl)cc1F CHEMBL5426056 IC50 700.0 nM
CO[C@H]1C[C@@H](C(C)(C)C)O[C@@H](c2onc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)C1 CHEMBL3982535 IC50 730.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1[C@H]1OC[C@@H](C(C)(C)C)O1 CHEMBL3898476 IC50 840.0 nM
COc1ccc2c(c1)CCCc1c(C(=O)Nc3c(C(F)(F)F)n(C)n(-c4ccccc4)c3=O)noc1-2 CHEMBL4567819 IC50 865.0 nM
COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)c(C(F)(F)F)c1 CHEMBL3970464 IC50 890.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(C(C)C)c2=O)noc1C1CCCC(C(C)(C)C)O1 CHEMBL3895951 IC50 980.0 nM
Cc1c(C(=O)Nc2c(C)n(C)n(-c3ccccc3F)c2=O)nnn1-c1ccc(C2CC2)cc1Cl CHEMBL3967415 IC50 1000.0 nM
COc1ccc(-c2onc(C(=O)Nc3c(C)n(C)n(-c4ccccc4F)c3=O)c2C)cc1 CHEMBL5402761 IC50 1000.0 nM