NC1CCN(S(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2ccc4c(c2)CC(=O)N4)C3)CC1 CHEMBL3798006 IC50 1.0 nM
NC1CCN(S(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2cc4c(cc2Cl)NC(=O)C4)C3)CC1 CHEMBL3797749 IC50 1.0 nM
CN1CCC(CS(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2ccc4c(c2)CC(=O)N4)C3)CC1 CHEMBL3797708 IC50 1.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)CC3CCN(CCCC(F)(F)F)CC3)c(Cl)cc2N1 CHEMBL3798741 Ki 1.1 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)N3CCC(NCc4ccccc4)CC3)c(Cl)cc2N1 CHEMBL3798468 alphaKi 1.1 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccc(F)cc3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4594207 IC50 1.3 nM
N[C@H]1CC[C@H](S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4573978 IC50 1.6 nM
CNC1CCN(S(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2cc4c(cc2Cl)NC(=O)C4)C3)CC1 CHEMBL3797949 IC50 2.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)CC3CCN(CCCO)CC3)c(Cl)cc2N1 CHEMBL3798012 IC50 2.0 nM
N[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4521928 IC50 2.5 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccccc3F)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4515665 IC50 2.5 nM
CN(C)C1CCN(S(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2cc4c(cc2Cl)NC(=O)C4)C3)CC1 CHEMBL3799643 IC50 3.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCCCC(F)(F)F)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4460946 IC50 3.2 nM
N[C@H]1CC[C@H](S(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2ccc4c(c2)CC(=O)N4)C3)CC1 CHEMBL3799083 IC50 4.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)C[C@H]3CCCNC3)c(Cl)cc2N1 CHEMBL3798745 IC50 4.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)CC3CCNCC3)c(Cl)cc2N1 CHEMBL3800480 IC50 4.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)CC3CCNCC3)ccc2N1 CHEMBL3799542 IC50 4.0 nM
NC1CCN(S(=O)(=O)N2[C@@H]3CC[C@H]2C[C@@H](NC(=O)c2cc4c(cc2F)NC(=O)C4)C3)CC1 CHEMBL3798134 IC50 5.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)C[C@@H]3CCCNC3)c(Cl)cc2N1 CHEMBL3797575 IC50 5.0 nM
CN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4587037 IC50 5.0 nM
Cc1ccc(CN[C@H]2CC[C@H](CS(=O)(=O)N3CCC(NC(=O)c4cc(C5CC5)on4)CC3)CC2)nc1 CHEMBL4586858 IC50 5.0 nM
O=C(NC1CCN(S(=O)(=O)[C@H]2CC[C@H](NCCCC(F)(F)F)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4476167 IC50 6.3 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3cccc(Cl)c3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4465232 IC50 8.0 nM
N[C@H]1CC[C@@H](S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4437408 IC50 10.0 nM
Cc1cccc(CN[C@H]2CC[C@H](CS(=O)(=O)N3CCC(NC(=O)c4cc(C5CC5)on4)CC3)CC2)c1 CHEMBL4578147 IC50 10.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3cc(F)ccn3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4472479 IC50 10.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccc(Cl)cc3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4559031 EC50 11.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)cc(-c4ccc(C5(N)CC5)cc4)nc3c2)C[C@H]1C CHEMBL4542517 IC50 11.7 nM
Cc1cc2c(cc1C(=O)N[C@H]1C[C@H]3CC[C@@H](C1)N3S(=O)(=O)N1CCC(N)CC1)CC(=O)N2 CHEMBL3798404 IC50 16.0 nM
O=C(NC1CCN(S(=O)(=O)c2ccc(CN3CCCC3)cc2)CC1)c1cc(C2CC2)on1 CHEMBL4536672 IC50 16.0 nM
CC(C)CN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4563960 IC50 16.0 nM
O=C(NC1CCN(S(=O)(=O)C2CCNCC2)CC1)c1cc(C2CC2)on1 CHEMBL4535915 Ki 17.0 nM
O=C(NC1CCN(S(=O)(=O)c2ccc(CN3CCC3)cc2)CC1)c1cc(C2CC2)on1 CHEMBL4476582 IC50 20.0 nM
CC(C)(C)CCN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4578574 IC50 20.0 nM
CCN(CCCC(F)(F)F)[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4563628 IC50 20.0 nM
Cc1ccc(CN[C@H]2CC[C@H](CS(=O)(=O)N3CCC(NC(=O)c4cc(C5CC5)on4)CC3)CC2)cc1 CHEMBL4527547 IC50 20.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccccc3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4465394 EC50 22.0 nM
NCCCCS(=O)(=O)N1CCC(NC(=O)c2cc(C3CC3)on2)CC1 CHEMBL4544590 IC50 25.0 nM
NC[C@H]1CC[C@H](S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4584607 IC50 25.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccccn3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4455165 IC50 25.0 nM
CN1C(=O)Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)N4S(=O)(=O)CC3CCNCC3)ccc21 CHEMBL3797524 IC50 26.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccc(Cl)cn3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4549988 EC50 26.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3cncc(F)c3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4551287 EC50 27.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccccc3Cl)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4574989 EC50 31.0 nM
CCN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4544413 IC50 32.0 nM
CCCN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4473729 IC50 32.0 nM
CCCCN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4565894 IC50 32.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3cccc(F)c3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4472528 EC50 38.0 nM
Cc1ccccc1CN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4532881 EC50 38.0 nM
O=C(NC1CCN(S(=O)(=O)C2CCNC2)CC1)c1cc(C2CC2)on1 CHEMBL4557510 IC50 40.0 nM
CC(C)(C)CN[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4441105 IC50 40.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3cccnc3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4449691 IC50 40.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCC(CCN)C4)CC1 CHEMBL5275589 IC50 40.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccc(F)cn3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4460507 EC50 42.0 nM
CN1CCC(S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4558640 IC50 50.0 nM
NCc1ccc(S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)cc1 CHEMBL4576240 IC50 63.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CC(CN)CC4)[C@@H](C)C1 CHEMBL4521324 IC50 67.0 nM
O=C1Cc2cc(C(=O)NC3CCN(S(=O)(=O)CC4CCNCC4)CC3)ccc2N1 CHEMBL3798488 IC50 70.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCCC(F)(F)F)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4584383 EC50 72.0 nM
CN(C)Cc1ccc(S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)cc1 CHEMBL4436720 IC50 79.0 nM
NCCCS(=O)(=O)N1CCC(NC(=O)c2cc3c(cc2Cl)NC(=O)C3)CC1 CHEMBL3797585 IC50 80.0 nM
C[C@H]1CC(=O)Nc2cc(C(=O)NCCC3CC3)ccc2N1C(=O)N1CC2CC2C1 CHEMBL4746525 IC50 88.0 nM
CCN1CCC(S(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4539611 IC50 100.0 nM
O=C(NC1CCN(S(=O)(=O)c2ccc(CN3CCCCC3)cc2)CC1)c1cc(C2CC2)on1 CHEMBL4447104 IC50 100.0 nM
O=C(NC1CCN(S(=O)(=O)CCCN2CCCC2)CC1)c1cc(C2CC2)on1 CHEMBL4588080 IC50 126.0 nM
CN(C)CCCN(CC[C@H](N)C(=O)O)C[C@@H]1O[C@H](n2cnc3c(N)ncnc32)[C@@H](O)[C@H]1O CHEMBL5205509 IC50 130.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)[C@@H](C)C1 CHEMBL4475972 IC50 140.0 nM
O=C(NC1CCN(S(=O)(=O)C[C@H]2CC[C@H](NCc3ccncc3)CC2)CC1)c1cc(C2CC2)on1 CHEMBL4527316 IC50 158.0 nM
NCCCS(=O)(=O)N1CCC(NC(=O)c2ccc3c(c2)CC(=O)N3)CC1 CHEMBL3797419 IC50 160.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)cc(-c4ccccc4)nc3c2)C[C@H]1C CHEMBL4472455 IC50 170.0 nM
CN(C)[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4460836 EC50 199.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)cc(-c4ccc(C(=O)NC)cc4)nc3c2)CC1 CHEMBL4575866 IC50 250.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)[C@H](C)C1 CHEMBL4450314 IC50 250.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)cc(-c4ccc(OC)cc4)nc3c2)CC1 CHEMBL4440399 IC50 260.0 nM
CN(CCCC(F)(F)F)[C@H]1CC[C@H](CS(=O)(=O)N2CCC(NC(=O)c3cc(C4CC4)on3)CC2)CC1 CHEMBL4452997 EC50 261.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)cc(-c4ccccc4)nc3c2)CC1 CHEMBL4551647 IC50 300.0 nM
CCCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)CC1 CHEMBL4448008 IC50 360.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)cc(-c4ccc(C)cc4)nc3c2)CC1 CHEMBL4579512 IC50 370.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)CC1 CHEMBL4530816 IC50 370.0 nM
O=C(NC1CCN(C(=O)CCl)CC1)c1cc(C2CC2)on1 CHEMBL5439323 IC50 370.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CC(CN)CC4)CC1 CHEMBL4584168 IC50 380.0 nM
NCCS(=O)(=O)N1CCC(NC(=O)c2cc(C3CC3)on2)CC1 CHEMBL4467253 IC50 398.0 nM
O=C1Cc2cc(C(=O)N[C@H]3C[C@H]4CC[C@@H](C3)C4S(=O)(=O)CC3CCN(CCCC(F)(F)F)CC3)c(Cl)cc2N1 CHEMBL5431436 IC50 689.0 nM
O=C1N(Cc2ccccc2)C[C@@H]2[C@@H](c3ccc(Br)cc3)[C@]3(O[C@]12O)C(=O)Nc1ccccc13 CHEMBL5422878 IC50 810.0 nM
CCCOC(=O)N1CCN(C(=O)c2ccc3c(Cl)c4c(nc3c2)CC(C)CC4)CC1 CHEMBL4532072 IC50 1000.0 nM