O=C(/C=C/c1ccc(F)cc1)N(Cc1ccco1)Cc1cc(F)ccc1[N+](=O)[O-] CHEMBL4637732 Kd 1.03 nM
COc1ccc(/C=C/C=C2\Oc3ccc(-c4ccc(OC)nc4)cc3C2=O)cc1 CHEMBL5286894 IC50 1.18 nM
O=C1/C(=C\C=C\c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccc(OCCF)cc1 CHEMBL3593932 Ki 2.1 nM
CN(C)c1ccc(-c2oc3cc(N(C)CCN4C(=O)C=CC4=O)ccc3c(=O)c2O)cc1 CHEMBL5274551 Ki 2.32 nM
COc1ccc(CN2C(=O)/C(=C\C=C\c3ccc([N+](=O)[O-])cc3)c3ccccc32)cc1OC CHEMBL3593930 Ki 3.5 nM
N#CC(C#N)=Cc1cn(Cc2ccccc2)c2ccccc12 CHEMBL5404722 Ki 3.5 nM
COc1cccc(CN2C(=O)/C(=C\C=C\c3ccc([N+](=O)[O-])cc3)c3ccccc32)c1 CHEMBL3593928 Ki 3.8 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(Cc3ccc([N+](=O)[O-])cc3)c3ccccc32)cc1 CHEMBL3593911 Ki 4.2 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(Cl)c2)cc1 CHEMBL2153085 EC50 7.0 nM
N#Cc1ccc(/C=C/C(=O)N(Cc2ccco2)Cc2ccccc2[N+](=O)[O-])cc1 CHEMBL4633757 Kd 8.21 nM
N#CC(C#N)=Cc1ccc2ccn(Cc3ccccc3)c2c1 CHEMBL5413730 Ki 8.5 nM
O=C1/C(=C\C=C\c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccc(OCC[18F])cc1 CHEMBL3593934 Kd 8.9 nM
N#CC(C#N)=C/C=C/C=C/c1cn(Cc2ccccc2)c2ccccc12 CHEMBL5436166 Ki 9.2 nM
N#CC(C#N)=C/C=C/c1cn(Cc2ccccc2)c2ncccc12 CHEMBL5435534 Ki 9.4 nM
O=C(Nc1ccccc1/C=C/c1ccc([N+](=O)[O-])cc1)c1ccccn1 CHEMBL5087695 Kd 10.0 nM
O=C(/C=C/c1ccc(F)cc1)N(Cc1ccccc1)Cc1cc(F)ccc1[N+](=O)[O-] CHEMBL4634055 Kd 10.9 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)Nc3ncccc32)cc1 CHEMBL3593904 Ki 11.5 nM
COc1ccc(CN2C(=O)/C(=C\C=C\c3ccc([N+](=O)[O-])cc3)c3ccccc32)cc1 CHEMBL3593926 Ki 12.9 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2)cc1 CHEMBL2153086 EC50 13.0 nM
N#Cc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1 CHEMBL2153084 EC50 14.0 nM
O=C1Nc2ccccc2/C1=C/C=C/c1ccc([N+](=O)[O-])cc1 CHEMBL3593922 Ki 14.6 nM
N#CC(C#N)=C/C=C/C=C/c1ccc2c(ccn2Cc2ccccc2)c1 CHEMBL5420714 Ki 14.6 nM
N#CC(C#N)=C/C=C/c1ccc2ccn(Cc3ccccc3)c2c1 CHEMBL5405459 Ki 15.5 nM
N#Cc1ccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)cc1 CHEMBL2153083 EC50 16.0 nM
N#CC(C#N)=C/C=C/c1cn(Cc2ccccc2)c2ccccc12 CHEMBL5399057 Ki 16.5 nM
COC(=O)/C(C#N)=C/c1cn(Cc2ccccc2)c2ccccc12 CHEMBL5422515 Ki 16.5 nM
N#CC(C#N)=Cc1cn(Cc2cccnc2)c2ccccc12 CHEMBL5414142 Ki 16.8 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cccc(F)c2)c1 CHEMBL3902249 EC50 17.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccco2)c1 CHEMBL3968863 EC50 17.0 nM
N#CC(C#N)=C/C=C/C=C/c1cn(Cc2cccnc2)c2ccccc12 CHEMBL5402429 Ki 17.3 nM
N#CC(C#N)=Cc1cn(Cc2ccc(F)cc2)c2ccccc12 CHEMBL5434091 Ki 17.3 nM
N#CC(C#N)=Cc1cn(Cc2ccc(I)cc2)c2ccccc12 CHEMBL5431199 Ki 17.4 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccsc2)cc1 CHEMBL3914948 EC50 18.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccc(F)cc2)c1 CHEMBL3978222 EC50 20.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccc(C(F)(F)F)cc2)cc1 CHEMBL3969389 EC50 22.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccc(Cl)cc2)cc1 CHEMBL3942516 EC50 22.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccoc2)cc1 CHEMBL3960518 EC50 23.0 nM
O=C1/C(=C\C=C\c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccccc1 CHEMBL3593924 Ki 25.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2)cn1 CHEMBL3945963 EC50 26.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2)cc1F CHEMBL3978672 EC50 27.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccsc2)c1 CHEMBL3935323 EC50 29.0 nM
N#CC(C#N)=C/C=C/C=C/c1ccc2ccn(Cc3ccccc3)c2c1 CHEMBL5415091 Ki 29.4 nM
COc1ccc(CN2C(=O)/C(=C\C=C\c3ccc(N(C)C)cc3)c3cccnc32)cc1 CHEMBL3593915 Ki 29.8 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cccs2)c1 CHEMBL3980090 EC50 30.0 nM
C[n+]1c(/C=C/c2ccc(N3CCCCC3)cc2)sc2ccccc21 CHEMBL5286480 Kd 30.0 nM
Cc1ccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)cc1 CHEMBL3966737 EC50 31.0 nM
N#Cc1cccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 CHEMBL3892786 EC50 31.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(C(F)(F)F)c2)cc1 CHEMBL3907207 EC50 31.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccccc2F)cc1 CHEMBL3916681 EC50 31.0 nM
N#CC(C#N)=Cc1cn(Cc2ccccc2)c2ncccc12 CHEMBL5423638 Ki 31.3 nM
N#Cc1ccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)cc1 CHEMBL3961796 EC50 32.0 nM
COc1ccc2c(c1)Sc1cc([N+](=O)[O-])ccc1N2 CHEMBL2063787 Ki 32.1 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cccc(Cl)c2)c1 CHEMBL3889741 EC50 36.0 nM
O=C1/C(=C/c2ccc(-c3ccc(CO)cc3)s2)Cc2ccccc21 CHEMBL5276896 Kd 39.0 nM
Cc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1 CHEMBL3949314 EC50 40.0 nM
COc1ccc(/C=C/c2ccccc2NC(=O)c2ccccc2)cc1 CHEMBL5074716 Kd 40.0 nM
CN(C)c1ccc2nc(/C=C/C=C/C=C(C#N)C#N)sc2c1 CHEMBL5283353 Kd 40.1 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)Nc3ccccc32)cc1 CHEMBL3593903 Ki 40.7 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(Cc3ccccc3)c3ccccc32)cc1 CHEMBL3593909 Ki 40.9 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccccc2F)c1 CHEMBL3973272 EC50 42.0 nM
N#CC(C#N)=C/C=C/C=C/c1cccc2c1ccn2Cc1ccccc1 CHEMBL5400950 Ki 42.4 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(Cc3ccc(N)cc3)c3ccccc32)cc1 CHEMBL3593916 Ki 43.6 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2)c(F)c1 CHEMBL3953030 EC50 44.0 nM
Nc1ccc(/C=C/C=C2\C(=O)Nc3ccccc32)cc1 CHEMBL3593918 Ki 44.8 nM
CCOC(=O)N1C(=O)/C(=C\C=C\c2ccc(N(C)C)cc2)c2ccccc21 CHEMBL3593913 Ki 45.3 nM
O=C(/C=C/c1ccc(F)cc1)N(Cc1ccccc1)Cc1ccccc1[N+](=O)[O-] CHEMBL4644640 Kd 47.34 nM
O=[N+]([O-])c1ccc2c(c1)Sc1cc(OCCF)ccc1N2 CHEMBL2063797 Ki 49.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cc(F)ccc2F)cc1 CHEMBL3898223 EC50 49.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccc(Cl)cc2)c1 CHEMBL3986437 EC50 50.0 nM
N#CC(C#N)=C/C=C/C=C/c1cccc2ccn(Cc3ccccc3)c12 CHEMBL5435422 Ki 50.9 nM
COc1ccc(CN2C(=O)/C(=C/C=C/c3ccc([N+](=O)[O-])cc3)c3ccccc32)cc1OC CHEMBL3593931 Ki 53.3 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)Nc3ccc(O)cc32)cc1 CHEMBL3593905 Ki 54.0 nM
COc1ccc(CN2C(=O)/C(=C\C=C\c3ccc(N(C)C)cc3)c3ccccc32)cc1 CHEMBL3593910 Ki 54.6 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cccc(C(F)(F)F)c2)c1 CHEMBL3916176 EC50 55.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccoc2)c1 CHEMBL3923979 EC50 56.0 nM
N#CC(C#N)=C/C=C/c1cccc2c1ccn2Cc1ccccc1 CHEMBL5401214 Ki 56.4 nM
O=[N+]([O-])c1ccc2c(c1)Sc1cc(OC/C=C/I)ccc1N2 CHEMBL2063798 Ki 57.9 nM
Cc1cccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 CHEMBL3978416 EC50 60.0 nM
COc1ccc(/C=C/C=C2\C(=O)Nc3ccccc32)cc1 CHEMBL3593902 Ki 61.1 nM
Cc1ccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)cc1 CHEMBL3940543 EC50 62.0 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(C)c3ccccc32)cc1 CHEMBL3593908 Ki 63.7 nM
COc1cccc(CN2C(=O)/C(=C/C=C/c3ccc([N+](=O)[O-])cc3)c3ccccc32)c1 CHEMBL3593929 Ki 64.7 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccccc2Cl)cc1 CHEMBL3925683 EC50 65.0 nM
N#Cc1ccccc1Cc1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 CHEMBL3927941 EC50 68.0 nM
CCNc1nc(NCc2ccc3c(c2)OCO3)nc(N2CCN(c3nc(N)nc(Nc4ccc(Oc5ccccc5)cc4)n3)CC2Cc2ccccc2)n1 CHEMBL5290387 Kd 68.0 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(c3ccccc3)c3ccccc32)cc1 CHEMBL3593917 Ki 68.1 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(Cc3ccccc3)c3ncccc32)cc1 CHEMBL3593914 Ki 68.3 nM
N#CC(C#N)=C/C=C/c1cn(Cc2cccnc2)c2ccccc12 CHEMBL5395343 Ki 69.4 nM
COc1ccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)cc1 CHEMBL2153087 EC50 70.0 nM
COc1ccc(/C=C/c2ccccc2NC(=O)c2ccccn2)cc1 CHEMBL5088083 Kd 70.0 nM
COc1ccc(/C=C/C=C2\C(=O)N(Cc3ccccc3)c3ccccc32)cc1 CHEMBL3593907 Ki 72.5 nM
N#Cc1ccc2[nH]cc(CCNC(=O)c3ccc(Cc4cccc(F)c4)cc3)c2c1 CHEMBL3982341 EC50 75.0 nM
O=[N+]([O-])c1ccc2c(c1)Sc1cc(Br)ccc1N2 CHEMBL2063788 Ki 75.3 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Nc2ccccc2)cc1 CHEMBL3894538 EC50 76.0 nM
O=C1/C(=C/C=C/c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccc(OCCF)cc1 CHEMBL3593933 Ki 76.1 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccccc2)c1 CHEMBL2153080 EC50 78.0 nM
COc1ccc(CN2C(=O)/C(=C\c3ccc(N(C)C)cc3)c3cccnc32)cc1 CHEMBL3593900 Ki 79.5 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccccc2C(F)(F)F)cc1 CHEMBL3977789 EC50 80.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccs2)cc1 CHEMBL3912400 EC50 81.0 nM
COc1ccc(CN2C(=O)/C(=C/C=C/c3ccc([N+](=O)[O-])cc3)c3ccccc32)cc1 CHEMBL3593927 Ki 81.9 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Nc2cccc(F)c2)cc1 CHEMBL3977750 EC50 82.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CNCc2cccs2)cc1 CHEMBL3979873 EC50 83.0 nM
COc1ccccc1Cc1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 CHEMBL3970056 EC50 84.0 nM
CN(C)c1ccc(/C=C2\C(=O)Nc3ccccc32)cc1 CHEMBL328710 Ki 84.4 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccc(F)cc2)cc1 CHEMBL3933818 EC50 86.0 nM
Oc1ccc(-c2nsc(-c3ccc(O)c(O)c3)n2)cc1O CHEMBL3663941 Ki 89.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cncc(F)c2)c1 CHEMBL2153088 EC50 90.0 nM
Cc1cccc(Oc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 CHEMBL3889797 EC50 91.0 nM
CN(C)c1ccc(/C=C/C=C2\C(=O)N(c3ccncc3)c3ccccc32)cc1 CHEMBL3593912 Ki 92.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CNCc2ccccc2)c1 CHEMBL3948723 EC50 94.0 nM
COc1ccccc1Cc1cccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1 CHEMBL3947027 EC50 96.0 nM
COc1cccc(Oc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 CHEMBL3962345 EC50 98.0 nM
CN(C)c1ccc(/C=C/c2ccccc2NC(=O)c2ccccn2)cc1 CHEMBL5092684 Kd 100.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CNCc2ccccc2)cc1 CHEMBL3934411 EC50 103.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccc(C(F)(F)F)cc2)c1 CHEMBL3901751 EC50 103.0 nM
N#CC(C#N)=C/C=C/c1cccc2ccn(Cc3ccccc3)c12 CHEMBL5428949 Ki 103.1 nM
Oc1ccc(-c2ccc(-c3ccc(O)c(O)c3)s2)cc1O CHEMBL3663947 Ki 105.0 nM
N#Cc1ccc(/C=C/C(=O)N(Cc2ccccc2)Cc2ccccc2[N+](=O)[O-])cc1 CHEMBL4639644 Kd 105.3 nM
O=[N+]([O-])c1ccc2c(c1)Sc1cc(I)ccc1N2 CHEMBL2063789 Ki 106.0 nM
N#Cc1ccc(/C=C/C(=O)N(Cc2ccccc2)Cc2ccccc2)cc1 CHEMBL4642469 Kd 106.9 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cccc(F)c2)n1 CHEMBL3986784 EC50 109.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cc(F)cc(F)c2)cc1 CHEMBL3917768 EC50 111.0 nM
COc1ccccc1N(Cc1ccccc1[N+](=O)[O-])C(=O)/C=C/c1ccccc1 CHEMBL4648610 Kd 111.6 nM
O=C(NCCc1c[nH]c2ccc(F)cc12)c1cccc(Cc2cccc(F)c2)c1 CHEMBL3936586 EC50 112.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Oc2cccc(F)c2)cc1 CHEMBL3907154 EC50 112.0 nM
COc1ccc(CN2C(=O)/C(=C\c3ccc(N(C)C)cc3)c3ccccc32)cc1 CHEMBL3593896 Ki 114.5 nM
N#Cc1ccc(/C=C/C(=O)N(CCc2ccccc2)Cc2ccccc2[N+](=O)[O-])cc1 CHEMBL4634968 Kd 115.5 nM
N#Cc1ccccc1Cc1cccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1 CHEMBL3925048 EC50 116.0 nM
O=[N+]([O-])c1ccc2c(c1)Sc1ccccc1N2 CHEMBL1976750 Ki 116.5 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccnc2)cc1 CHEMBL3959578 EC50 117.0 nM
COc1ccc2c(c1)Sc1cc(OC)ccc1N2 CHEMBL2063785 Ki 121.8 nM
N#Cc1cccc(Nc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 CHEMBL3918360 EC50 122.0 nM
N#CC(C#N)=C/C=C/C=C/c1cn(Cc2ccccc2)c2ncccc12 CHEMBL5420492 Ki 123.1 nM
CN(C)c1ccc(/C=C2\C(=O)Nc3ncccc32)cc1 CHEMBL3593893 Ki 124.3 nM
COc1cccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1 CHEMBL3919598 EC50 125.0 nM
N#Cc1cccc(Cc2ccc(C(=O)NCc3c[nH]c4ccc(Cl)cc34)cc2)c1 CHEMBL3950534 EC50 132.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccco2)cc1 CHEMBL3950141 EC50 133.0 nM
Oc1ccc(-c2nnc(-c3cc(O)c(O)cc3Br)s2)cc1O CHEMBL3663950 Ki 135.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2F)cc1 CHEMBL3935190 EC50 139.0 nM
CN(C)c1ccc(/C=C/c2ccccc2NC(=O)c2cccnn2)cc1 CHEMBL5086296 Kd 140.0 nM
O=C(Nc1ccccc1/C=C/c1ccc([N+](=O)[O-])cc1)c1ccccc1 CHEMBL5075163 Kd 140.0 nM
CN(C)c1ccc(/C=C2\C(=O)N(Cc3ccccc3)c3ccccc32)cc1 CHEMBL3593895 Ki 144.4 nM
COc1ccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)cc1 CHEMBL3947393 EC50 147.0 nM
COc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1F CHEMBL3921153 EC50 148.0 nM
CN(C)c1ccc(/C=C2\C(=O)N(c3ccncc3)c3ccccc32)cc1 CHEMBL3593897 Ki 149.8 nM
CN(C)c1ccc(/C=C/c2ccccc2NC(=O)c2ccccc2)cc1 CHEMBL5072207 Kd 150.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccncc2)cc1 CHEMBL3950766 EC50 151.0 nM
CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccc(N(C)C)cc2)cc1 CHEMBL64894 Potency 151.46 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccccc2)cc1 CHEMBL3908965 EC50 154.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CNCc2cccs2)c1 CHEMBL3957251 EC50 159.0 nM
O=P(O)(O)c1c2c(c(P(=O)(O)O)c3c1[C@H]1C[C@@H]3c3cc4c(cc31)[C@H]1C[C@@H]4c3ccccc31)[C@H]1C[C@@H]2c2cc3c(cc21)[C@H]1C[C@@H]3c2ccccc21 CHEMBL4763384 Kd 160.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Nc2ccccc2)c1 CHEMBL2153082 EC50 161.0 nM
O=C(NCCc1c[nH]c2ccc(N3CCOCC3)cc12)c1ccc(Cc2cccc(F)c2)cc1 CHEMBL3908911 EC50 166.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CNCC2CCCCC2)cc1 CHEMBL3972928 EC50 168.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cn2cccn2)cc1 CHEMBL3931074 EC50 173.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cc(F)cc(F)c2)c1 CHEMBL3911727 EC50 174.0 nM
Oc1ccc(-c2cnc(-c3cc(O)c(O)cc3Br)s2)cc1O CHEMBL3663958 Ki 177.0 nM
COc1ccc(/C=C/c2cccc(NC(=O)c3ccccc3)c2)cc1 CHEMBL5075837 Kd 180.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=O)C(C)(C)CCC1 CHEMBL81379 IC50 190.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1 CHEMBL986 IC50 190.0 nM
Brc1cccc(-c2cc(-c3ccc4c(c3)OCO4)n[nH]2)c1 CHEMBL4748063 Kd 190.0 nM
O=C1/C(=C/C=C/c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccccc1 CHEMBL3593925 Ki 192.7 nM
O=C1Nc2ccccc2/C1=C/C=C/c1ccccc1 CHEMBL3593901 Ki 206.7 nM
CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 CHEMBL52 IC50 210.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@H](Cc1ccc(O)c(O)c1)C(=O)O CHEMBL324842 IC50 210.0 nM
O=C1Nc2ccccc2/C1=C\C=C\c1ccc([N+](=O)[O-])cc1 CHEMBL3593923 Ki 211.4 nM
COc1cc(-c2nnc(-c3cc(O)c(O)cc3I)s2)ccc1O CHEMBL3663956 Ki 219.0 nM
COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O CHEMBL140 IC50 220.0 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 IC50 220.0 nM
Oc1ccc(-c2ncc(-c3cc(O)c(O)cc3Br)s2)cc1O CHEMBL3663940 Ki 224.0 nM
O=C1/C(=C\C=C\c2ccccc2)c2ccccc2N1Cc1ccccc1 CHEMBL3593906 Ki 226.9 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccccc1Cc1ccccc1 CHEMBL3907691 EC50 240.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Oc2ccccc2)c1 CHEMBL3942591 EC50 241.0 nM
O=C(NCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cc(F)cc(F)c2)cc1 CHEMBL3898561 EC50 242.0 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)CCCC1 CHEMBL4787961 IC50 250.0 nM
COc1ccc(/C=C/c2ccccc2NC(=O)Cc2ccccc2)cc1 CHEMBL5085623 Kd 250.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cn2cccn2)c1 CHEMBL3890440 EC50 256.0 nM
CN(c1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1)c1cccc(F)c1 CHEMBL3903710 EC50 264.0 nM
Oc1ccc(-c2nnc(-c3ccc(O)c(O)c3)s2)cc1O CHEMBL3663955 Ki 270.0 nM
CN(c1ccccc1)c1cccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)c1 CHEMBL3963240 EC50 270.0 nM
C#CCN(C)[C@H](C)Cc1ccccc1 CHEMBL972 IC50 270.0 nM
O=C(NCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2cccc(F)c2)cc1 CHEMBL3911145 EC50 277.0 nM
Oc1ccc(-c2ccc(-c3cc(O)c(O)c(O)c3)s2)cc1O CHEMBL3663942 Ki 283.0 nM
CN(C)c1ccc(/C=C2\C(=O)N(c3ccccc3)c3ccccc32)cc1 CHEMBL3593252 Ki 290.2 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Oc2ccccc2)cc1 CHEMBL3980307 EC50 293.0 nM
O=C(NCCc1c[nH]c2ccc(C(F)(F)F)cc12)c1ccc(Cc2cccc(F)c2)cc1 CHEMBL3985793 EC50 320.0 nM
COc1ccc(/C=C/c2ccccc2NC(=O)c2ccn[nH]2)cc1 CHEMBL5080710 Kd 320.0 nM
Oc1ccc(-c2ccc(-c3cc(O)c(O)c(I)c3)s2)cc1O CHEMBL3663957 Ki 330.0 nM
CC(=O)Oc1ccc(-c2nnc(-c3cc(OC(C)=O)c(OC(C)=O)cc3I)s2)cc1OC(C)=O CHEMBL3663959 Ki 330.0 nM
COc1ccccc1CN(Cc1cc(F)ccc1[N+](=O)[O-])C(=O)/C=C/c1ccc(F)cc1 CHEMBL4647336 Kd 331.7 nM
CCOC(=O)N1C(=O)/C(=C\c2ccc(N(C)C)cc2)c2ccccc21 CHEMBL3593898 Ki 342.6 nM
CC(C)(C)NC(=O)c1ccc(/C=C/C(=O)N(Cc2ccccc2)Cc2ccccc2[N+](=O)[O-])cc1 CHEMBL4645133 Kd 344.0 nM
COc1ccc2c(c1)Sc1cc(C#N)ccc1N2 CHEMBL2063786 Ki 346.0 nM
O=C1Nc2ccccc2/C1=C/c1ccc([N+](=O)[O-])cc1 CHEMBL201986 Ki 347.2 nM
CN(C)c1ccc(/C=C2\C(=O)N(Cc3ccccc3)c3ncccc32)cc1 CHEMBL3593899 Ki 350.2 nM
Oc1ccc(-c2nnc(-c3cc(O)c(O)cc3O)o2)cc1O CHEMBL3663946 Ki 370.0 nM
Cc1ccccc1Cc1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 CHEMBL3910404 EC50 370.0 nM
O=C(Nc1ccccc1/C=C/c1cccc([N+](=O)[O-])c1)c1ccccc1 CHEMBL5084363 Kd 380.0 nM
COc1cccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)c1F CHEMBL3981695 EC50 386.0 nM
Cc1cccc(C)c1Cc1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 CHEMBL3890252 EC50 398.0 nM
O=C(Nc1ccccc1/C=C/c1ccc(F)cc1)c1ccccc1 CHEMBL5078735 Kd 400.0 nM
CN(C)c1ccc(/C=C2\C(=O)Nc3ccc(O)cc32)cc1 CHEMBL3593894 Ki 407.1 nM
COc1ccc(/C=C/c2ccccc2NC(=O)c2ccncc2)cc1 CHEMBL5092932 Kd 420.0 nM
Nc1c(/N=N/c2ccc(-c3ccc(/N=N/c4cc(S(=O)(=O)O)c5ccccc5c4N)cc3)cc2)cc(S(=O)(=O)O)c2ccccc12 CHEMBL116955 Potency 423.25 nM
N#Cc1ccc(/C=C/C(=O)N(Cc2ccccc2[N+](=O)[O-])c2ccccc2)cc1 CHEMBL4639096 Kd 439.2 nM
Oc1ccc(-c2nnc(-c3ccc(O)c(O)c3)o2)cc1O CHEMBL3663951 Ki 466.0 nM
CN(c1ccccc1)c1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 CHEMBL3949484 EC50 470.0 nM
O=C1/C(=C\c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccccc1 CHEMBL3593920 Ki 482.9 nM
N#Cc1ccc(/C=C/C(=O)N(Cc2ccccc2)Cc2cc(F)ccc2[N+](=O)[O-])cc1 CHEMBL4637739 Kd 484.6 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cn2ccnc2)cc1 CHEMBL3906607 EC50 486.0 nM
O=C(Nc1cccc(/C=C/c2ccc(F)cc2)c1)c1ccccc1 CHEMBL5069753 Kd 490.0 nM
Oc1ccc(-c2ccc(Br)s2)cc1O CHEMBL3663949 Ki 506.0 nM
CN(C)c1ccc(/C=C2\C(=O)N(C)c3ccccc32)cc1 CHEMBL86921 Ki 507.6 nM
NCCc1ccc(O)c(O)c1 CHEMBL59 IC50 530.0 nM
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nc(=O)c(O)nn3C)CS[C@H]12)c1csc(N)n1 CHEMBL161 Kd 530.0 nM
Cc1[nH]c2ccc(Cl)cc2c1CCNC(=O)c1ccc(Cc2cccc(F)c2)cc1 CHEMBL3912717 EC50 535.0 nM
O=C(NCCc1c[nH]c2ccc(-c3ccccc3)cc12)c1ccc(Cc2cccc(F)c2)cc1 CHEMBL3896453 EC50 537.0 nM
COc1ccc(CN(Cc2ccccc2)C(=O)/C=C/c2ccc(C#N)cc2)cc1 CHEMBL4644590 Kd 565.3 nM
Cn1cc(CCNC(=O)c2ccc(Cc3cccc(F)c3)cc2)c2cc(Cl)ccc21 CHEMBL3965930 EC50 581.0 nM
COc1cc(/C=C/C(=O)C(=Cc2c[nH]c3ccccc23)C(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O CHEMBL5435474 IC50 610.0 nM
O=C1Nc2ccccc2/C1=C\c1ccc([N+](=O)[O-])cc1 CHEMBL3593919 Ki 621.8 nM
Oc1ccc(-c2cnc(-c3cc(O)c(O)cc3Br)o2)cc1O CHEMBL3663960 Ki 639.0 nM
COc1ccc(/C=C/c2ccccc2NC(=O)NCc2ccccc2)cc1 CHEMBL5070762 Kd 640.0 nM
O=C(/C=C/c1ccc(/C=C/C(=O)c2ccc(O)c(O)c2)cc1)c1ccc(O)c(O)c1 CHEMBL4075833 IC50 640.0 nM
Oc1ccc(-c2cnc(-c3ccc(O)c(O)c3)o2)cc1O CHEMBL3663954 Ki 659.0 nM
O=C(/C=C/c1ccc(/C=C/C(=O)c2ccc(O)c(F)c2)cc1)c1ccc(O)c(F)c1 CHEMBL5394205 IC50 660.0 nM
COc1ccc2c(c1)sc(-c1ccc(N3CCCC3)cc1)[n+]2C CHEMBL5278856 Kd 680.0 nM
Oc1ccc(-c2cc(Br)c(-c3ccc(O)c(O)c3)s2)cc1O CHEMBL3663938 Ki 697.0 nM
Oc1ccc(-c2cn(-c3ccc(O)c(O)c3)nn2)cc1O CHEMBL3663952 Ki 697.0 nM
COc1ccc(/C=C/c2ccccc2NC(=O)c2nccs2)cc1 CHEMBL5082879 Kd 700.0 nM
O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CNC2CCCCC2)c1 CHEMBL3977892 EC50 724.0 nM
COc1cc(/C=C/C(=O)O)ccc1O CHEMBL32749 IC50 750.0 nM
Oc1ccc(-c2ncc(Br)s2)cc1O CHEMBL3663953 Ki 765.0 nM
Cc1cc(-c2ccc(/N=N\c3ccc4c(S(=O)(=O)O)cc(S(=O)(=O)O)c(N)c4c3O)c(C)c2)ccc1/N=N\c1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)c(N)c2c1O CHEMBL1607905 Potency 773.57 nM
Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@H](O)C2 CHEMBL583912 IC50 800.0 nM
O=C(Nc1ccc(O)c(O)c1)c1cc(O)c(O)cc1Br CHEMBL3663944 Ki 813.0 nM
O=C(/C=C/c1ccc(C(=O)N2CCOCC2)cc1)N(Cc1ccccc1)Cc1cccc(Cl)c1 CHEMBL4646198 Kd 871.8 nM
O=C(/C=C/c1cc(O)c(O)cc1Br)c1ccc(O)c(O)c1 CHEMBL3663964 Ki 890.0 nM
O=C1/C(=C/c2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccccc1 CHEMBL3593921 Ki 959.3 nM
Cc1ccc2c(c1)sc(-c1ccc(N(C)C)cc1)[n+]2C CHEMBL224392 Kd 969.0 nM
O=[N+]([O-])c1cc(O)c(O)cc1Cc1cc(O)c(O)cc1[N+](=O)[O-] CHEMBL3663961 Ki 970.0 nM
O=C(Nc1ccc(NC(=O)c2cc(O)c(O)c(O)c2)cc1)c1ccc(O)cc1 CHEMBL4641523 IC50 980.0 nM