CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3s2)CC1 CHEMBL4281138 IC50 3.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)C(Cc1ccccc1)Cc1ccc(OC(=O)CN2CCCCCC2=O)cc1 CHEMBL3936899 IC50 3.2 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)C(Cc1ccccc1)Cc1ccc(OC(=O)CCCCCCN2CCCCCC2=O)cc1 CHEMBL3899908 IC50 3.6 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)C(Cc1ccccc1)Cc1ccccc1 CHEMBL3894947 IC50 4.2 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CCCCCCCCSc1nc2ccccc2o1 CHEMBL4247249 IC50 7.0 nM
CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3o2)CC1 CHEMBL4282905 IC50 9.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccc(N(C)C)cc2)CCCC1 CHEMBL46423 IC50 9.0 nM
COc1ccc(N2CCN(CCCCC3(C)COC(c4nc(-c5ccccc5)c(-c5ccccc5)[nH]4)OC3)CC2)cc1 CHEMBL284596 IC50 10.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)C(Cc1ccccc1)Cc1ccc(O)cc1 CHEMBL3905226 IC50 10.3 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C(=O)N[C@H](C)C(=O)N[C@H]([C@@H](C)CC)C(=O)O1 CHEMBL449307 IC50 20.0 nM
CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(C(C)C)cccc2C(C)C)c(C(C)C)c1 CHEMBL101309 IC50 25.0 nM
CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1 CHEMBL4288347 IC50 26.0 nM
CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cc(N)cc2C(C)C)c(-c2cccc(OCCCO)c2)c2cccnc21 CHEMBL454397 IC50 31.0 nM
CCCCOc1ccccc1N1CCC(CNC(=O)Nc2c(C(C)C)cc(N)cc2C(C)C)(c2cccc(OC)c2)CC1 CHEMBL449832 IC50 32.0 nM
COc1ccccc1N1CCC(CNC(=O)Nc2c(C(C)C)cc(N)cc2C(C)C)(c2cccc(C(F)(F)F)c2)CC1 CHEMBL453491 IC50 32.0 nM
CCCCCCCCCN(CC(C)(C)C)C(=O)N[C@H]1CCCC[C@@H]1OC(=O)CCNC(=O)[C@@H]1OC(C)(C)OCC1(C)C CHEMBL2397474 IC50 32.0 nM
Cc1cc(C)n(CCCCCSc2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)n1 CHEMBL33780 IC50 35.0 nM
C/C=C/C/C=C/C/C=C/C/C=C/C/C=C/C/C=C/CCCC(=O)Nc1c(C(C)C)cccc1C(C)C CHEMBL304267 IC50 35.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cccc3C(C)C)CCN(c3ccccc3)CC2)c1 CHEMBL459999 IC50 35.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)CCN(c3ccccc3OC)CC2)c1 CHEMBL500498 IC50 37.0 nM
CCCCCCCCCCCCS[C@H](C(=O)Nc1cc(C)c(O)c(C)c1C)c1ccccc1 CHEMBL1908306 IC50 39.0 nM
O=C(N[C@@H]1c2ccccc2C[C@@H]1c1ccc(O)cc1)C(c1ccccc1)c1ccccc1 CHEMBL297271 IC50 40.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)CCN(c3ccccc3)CC2)c1 CHEMBL449977 IC50 40.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@H]([C@@H](C)CC)C(=O)O1 CHEMBL505016 IC50 40.0 nM
COc1ccccc1N1CCC(CNC(=O)Nc2c(C(C)C)cc(N)cc2C(C)C)(c2ccccc2OC)CC1 CHEMBL501429 IC50 43.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cccc3C(C)C)CCN(c3ccccc3OC)CC2)c1 CHEMBL510453 IC50 47.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)CCN(c3ccccc3OCC(F)(F)F)CC2)c1 CHEMBL503766 IC50 48.0 nM
COc1cccc(N2CCC(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)(c3cccc(OC)c3)CC2)c1 CHEMBL442567 IC50 48.0 nM
COc1ccc(C2(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)CCN(c3ccccc3OC)CC2)cc1 CHEMBL447674 IC50 49.0 nM
CN(CCCCC1(C)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1)c1ccccn1 CHEMBL284378 IC50 50.0 nM
CC1(CCCCN2CCN(c3nccs3)CC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL34219 IC50 50.0 nM
CC(=O)OC[C@@]1(C)C2C[C@H](OC(C)=O)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)C3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL25532 IC50 58.0 nM
CC1(CCCCN2CCc3ccccc3C2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL33054 IC50 60.0 nM
Cc1cc(C)n(CCCCCC2(C)COC(c3nc(-c4ccccc4)c(-c4ccccc4)[nH]3)OC2)n1 CHEMBL285429 IC50 60.0 nM
Cc1cc(C)n(CCC[C@H]2CO[C@@H](c3nc(-c4ccccc4)c(-c4ccccc4)[nH]3)OC2)n1 CHEMBL5284960 IC50 60.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccccc2)O[C@H](C)[C@@H](C)O1 CHEMBL40685 IC50 63.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)CCN(c3ccccc3OC(F)(F)F)CC2)c1 CHEMBL509834 IC50 68.0 nM
CC1(CCCCN2CCSCC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL286611 IC50 70.0 nM
CC1(CCCCN2CCN(c3ccccc3)CC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL33229 IC50 70.0 nM
c1ccc(-c2nc([C@H]3OC[C@@H](CCCCN4CCSCC4)CO3)[nH]c2-c2ccccc2)cc1 CHEMBL5275490 IC50 70.0 nM
Cc1cc(C)n(CCCCC2(C)COC(c3nc(-c4ccccc4)c(-c4ccccc4)[nH]3)OC2)n1 CHEMBL30860 IC50 75.0 nM
CC1(CCCCN2CCN(c3ncccn3)CC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL286434 IC50 75.0 nM
COc1ccccc1N1CCC(CNC(=O)Nc2c(C(C)C)cc(N)cc2C(C)C)(c2cccc(F)c2)CC1 CHEMBL443151 IC50 77.0 nM
CCCc1c(-c2nc(Cc3ccccc3)no2)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1258709 IC50 77.0 nM
O=C(O)C[C@H]1CC[C@H](c2ccc(NC(=O)c3nnc(Nc4ccc(F)c(F)c4)o3)cc2)CC1 CHEMBL2036730 IC50 80.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)ccc(N)c3C(C)C)CCN(c3ccccc3OC)CC2)c1 CHEMBL499122 IC50 81.0 nM
COc1ccccc1N1CCC(CNC(=O)Nc2c(C(C)C)cc(N)cc2C(C)C)(c2ccccc2)CC1 CHEMBL448407 IC50 82.0 nM
CCCc1c(-c2nc(C(C)(C)C)no2)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1258375 IC50 83.0 nM
CCCCCCCCCCCCC/C(S)=N/c1c(C(C)C)cccc1C(C)C CHEMBL64237 IC50 89.0 nM
CC1(CCCCN2CCN(Cc3ccccc3)CC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL286836 IC50 90.0 nM
CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ncccc3o2)CC1 CHEMBL4291768 IC50 100.0 nM
CC1(CCCCN2CCN(c3ccccn3)CC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL33127 IC50 105.0 nM
Cc1cc(C)n(CCCCC[S+]([O-])c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)n1 CHEMBL33661 IC50 108.0 nM
CC1(CCCCn2cc(-c3ccccc3)cn2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL33464 IC50 110.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C(=O)N[C@@H](CO)C(=O)N[C@H]([C@@H](C)CC)C(=O)O1 CHEMBL1933478 IC50 110.0 nM
CSc1cccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)c1 CHEMBL2334201 IC50 110.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3cccc(Br)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2333809 IC50 120.0 nM
CO[C@@]12Nc3cccc(CC4OC4(C)C)c3[C@]1(O)C[C@@H]1CC[C@@]3(O)[C@@]45O[C@@H]4[C@@H]4O[C@H](C=C(C)C)OC(C)(C)[C@H]4O[C@H]5CC[C@]3(C)[C@]12C CHEMBL5280709 IC50 120.0 nM
CC1(CCCCn2ncc3ccccc32)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL286583 IC50 130.0 nM
CCCCCCCC/C=C\CCCCCCCC(=O)Nc1ccccc1 CHEMBL15611 IC50 140.0 nM
CCCCCCCN(Cc1ccc(CC(C)(C)C)cc1)C(=O)Nc1ccc(F)cc1F CHEMBL277986 IC50 140.0 nM
COc1ccc(N2CCC(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)(c3cccc(OC)c3)CC2)cc1 CHEMBL364823 IC50 142.0 nM
COc1cccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)c1 CHEMBL2334205 IC50 150.0 nM
C=Cc1cccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)c1 CHEMBL2334204 IC50 150.0 nM
Cc1cc(C)n(CCCCC[S@+]([O-])c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)n1 CHEMBL5267175 IC50 160.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCN(CCSc2nc3ccccc3s2)CC1 CHEMBL4280317 IC50 170.0 nM
CCCc1c(-c2nc(N(C)C)no2)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1257329 IC50 190.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccccc3I)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334198 IC50 190.0 nM
CCc1ccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)cc1 CHEMBL2333808 IC50 190.0 nM
CCCCCCCCCCC(C)(C)C(=O)Nc1c(OC)cc(OC)cc1OC CHEMBL22373 IC50 200.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3cccc(Cl)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334200 IC50 210.0 nM
CN(CCCCC1(C)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1)Cc1ccccc1 CHEMBL287013 IC50 220.0 nM
CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1-c1ccc(Cl)cc1 CHEMBL1258708 IC50 220.0 nM
CCCc1c(-c2nc(C3CCCC3)no2)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1258829 IC50 230.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3cccc(F)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334540 IC50 230.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3cccc(I)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334197 IC50 250.0 nM
CC(C)c1cc(C(C)C)c(NC(=O)CN2CCN(CCSc3nc4ccccc4o3)CC2)c(C(C)C)c1 CHEMBL4283167 IC50 250.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCN(CCCSc2nc3ccccc3o2)CC1 CHEMBL4287597 IC50 250.0 nM
CCCc1noc(-c2c(C(=O)OCC)c3c(-c4ccccc4)cc(N4CCOCC4)nn3c2CCC)n1 CHEMBL1258147 IC50 260.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCN(CCSc2nc3ccccc3o2)CC1 CHEMBL4294841 IC50 260.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(C)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334222 IC50 270.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C2=N[C@H](CO2)C(=O)N[C@H](C2CCCCC2)C(=O)O1 CHEMBL1933480 IC50 280.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1 CHEMBL4284218 IC50 280.0 nM
CC1(CCCCN2CCOCC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL287233 IC50 300.0 nM
CC1(CCCCOCc2ccccc2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL284559 IC50 300.0 nM
CCCCCCCCN1CCc2c(C)c(CC(=O)O)c(C)c(NC(=O)C(C)(C)C)c21 CHEMBL478858 IC50 300.0 nM
CCCCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1257918 IC50 300.0 nM
Cc1cc2c(c(=O)o1)C=C1CC[C@H](C(C)CNCc3ccc(O)cc3)C[C@@H]1O2 CHEMBL2170736 IC50 300.0 nM
CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1-c1cccc(Cl)c1 CHEMBL1258600 IC50 310.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C(=O)N[C@H](CO)C(=O)N[C@H](C2CCCCC2)C(=O)O1 CHEMBL1933479 IC50 310.0 nM
O=C(Nc1ccc(O[C@H]2CC[C@@H](C(=O)O)CC2)cc1F)c1nnc(Nc2cc(F)c(F)cc2F)o1 CHEMBL3133014 IC50 310.0 nM
O=C(O)C[C@H]1CC[C@H](c2ccc(-c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cc3)cc2)CC1 CHEMBL4557603 IC50 325.0 nM
CCCCCCCCN1CCc2c(C)c(CN)c(C)c(NC(=O)C(C)(C)C)c21 CHEMBL478015 IC50 330.0 nM
C[C@@]12CO[C@@H](c3ccccc3F)O[C@H]1CC[C@@]1(C)[C@H]2C[C@H](OC(=O)c2ccc(C#N)cc2)[C@@]2(C)Oc3cc(-c4cccnc4)oc(=O)c3[C@H](O)[C@H]12 CHEMBL2398811 IC50 330.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccc(O)cc2)O[C@H](C)[C@@H](C)O1 CHEMBL291052 IC50 332.0 nM
CC(C)c1cc(C(C)C)c(NC(=O)CN2CCN(CCSc3nc4ncccc4o3)CC2)c(C(C)C)c1 CHEMBL4294442 IC50 370.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CC[C@H]1CCCC[C@H]1CSc1nc2ccccc2o1 CHEMBL4277672 IC50 370.0 nM
CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3cccc(F)c3)cc(N3CCOCC3)nn12 CHEMBL1257559 IC50 380.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(C#N)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(=O)c1ccccc1 CHEMBL2375707 IC50 390.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@H]([C@@H](C)CC)C(=O)O1 CHEMBL409855 IC50 410.0 nM
CC(C)c1cc(C(C)C)c(NC(=O)CN2CCN(CCSc3nc4ccccc4s3)CC2)c(C(C)C)c1 CHEMBL4293342 IC50 410.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccccc3C)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334203 IC50 420.0 nM
CC1(C)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 CHEMBL286812 IC50 430.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(C)c(F)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334215 IC50 430.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCCN(CCCSc2nc3ccccc3o2)CC1 CHEMBL4279691 IC50 430.0 nM
CCCCCCCCCCCCS(=O)(=O)C1=CC(=O)c2c(OC)ccc(OC)c2C1=O CHEMBL2335528 IC50 440.0 nM
O=C(Nc1ccc(O[C@H]2CC[C@@H](C(=O)O)CC2)cc1)c1nnc(Nc2cc(F)c(F)cc2F)o1 CHEMBL3133011 IC50 450.0 nM
CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1 CHEMBL3890942 IC50 450.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCN(CCSc2nc3ncccc3o2)CC1 CHEMBL4294421 IC50 450.0 nM
CSc1cc(C)nc(SC)c1NC(=O)CCN1CCN(CCSc2nc3ccccc3[nH]2)CC1 CHEMBL5284491 IC50 450.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc4c(c3)OC(F)(F)O4)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334224 IC50 460.0 nM
CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1-c1cccc(OC)c1 CHEMBL1258487 IC50 470.0 nM
O=C(O)C[C@H]1CC[C@H](c2ccc(-c3ccc(-c4nc5cc(Cl)ccc5[nH]4)cc3)cc2)CC1 CHEMBL4531443 IC50 485.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(Br)c(F)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334212 IC50 490.0 nM
CC(C)c1cc(C(C)C)c(NC(=O)CN2CCN(CCSc3nc4ccccc4[nH]3)CC2)c(C(C)C)c1 CHEMBL4291024 IC50 490.0 nM
CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3ccccc3)nc(N3CCOCC3)nn12 CHEMBL1257443 IC50 500.0 nM
COc1ccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)cc1 CHEMBL2334538 IC50 510.0 nM
CSc1ccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)cc1 CHEMBL2333812 IC50 540.0 nM
CCCN1CCC(CNC(=O)Nc2c(C(C)C)cccc2C(C)C)(c2cccc(OC)c2)CC1 CHEMBL459998 IC50 547.0 nM
CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1-c1ccccc1 CHEMBL1258374 IC50 550.0 nM
CC(C)=CC[C@@H](OC(=O)CC(C)C)C1=CC(=O)c2c(O)ccc(O)c2C1=O CHEMBL395857 IC50 600.0 nM
CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1-c1ccc(OC)cc1 CHEMBL1258943 IC50 600.0 nM
CCCCCCCCCCSC1=CC(=O)c2ccccc2C1=O CHEMBL2335539 IC50 600.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C)C(=O)N[C@H](CC(C)C)C(=O)O1 CHEMBL516093 IC50 600.0 nM
O=C(O)C[C@H]1CC[C@@H](Oc2ccc(-c3ccc(-c4nc5c(F)cc(F)cc5[nH]4)cn3)cn2)CC1 CHEMBL4458847 IC50 606.0 nM
CC(=O)OCC1(C)C(OC(C)=O)CCC2(C)C3C(=O)C4=C(O)OC(c5cccnc5)C=C4OC3(C)C(OC(C)=O)=CC12 CHEMBL179229 IC50 640.0 nM
CCCCCCCCN1CCc2c(C)cc(C)c(NC(=O)C(C)(C)C)c21 CHEMBL513892 IC50 640.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(C#N)c(F)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334217 IC50 650.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3cccc(C)c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334196 IC50 650.0 nM
CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3ccccc3)cc(N(C)C)nn12 CHEMBL1257442 IC50 660.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(N=[N+]=[N-])cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334199 IC50 660.0 nM
COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cccc3C(C)C)CCN(C)CC2)c1 CHEMBL459791 IC50 664.0 nM
CC(C)=C[C@H]1O[C@H]2[C@H]3O[C@@]34[C@H](CC[C@@]3(C)[C@@]4(O)CC[C@H]4C[C@@]5(O)c6c(CC7OC7(C)C)cccc6N[C@@]5(O)[C@@]43C)O[C@@H]2C(C)(C)O1 CHEMBL5283833 IC50 670.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccccc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334220 IC50 680.0 nM
CCCc1c(-c2nc(C3CCCCC3)no2)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1258944 IC50 690.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(Cl)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334541 IC50 690.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(-c4ccccc4)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334221 IC50 700.0 nM
C=Cc1ccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)cc1 CHEMBL2334195 IC50 710.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc4ccccc4c3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334223 IC50 710.0 nM
CCCc1c(-c2nc(N3CCCC3)no2)c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn12 CHEMBL1257209 IC50 770.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(F)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2333810 IC50 790.0 nM
C[C@@]12CO[C@@H](c3ccccc3)O[C@H]1CC[C@@]1(C)[C@H]2C[C@H](OC(=O)c2ccccc2C#N)[C@@]2(C)Oc3cc(-c4cccnc4)oc(=O)c3[C@H](O)[C@H]12 CHEMBL2398802 IC50 790.0 nM
CCCC[C@H](C)[C@@H]1CC(=O)N[C@@H](C(c2ccccc2)c2ccccc2)C(=O)N[C@H](Cn2cc(CNC(=O)CCCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@@H]43)nn2)C(=O)N[C@H](C2CCCCC2)C(=O)O1 CHEMBL1933481 IC50 800.0 nM
Cc1cc2c(c(=O)o1)C=C1CC[C@H](C(C)CNCc3ccc(O)c4ccccc34)C[C@@H]1O2 CHEMBL2170728 IC50 800.0 nM
Cc1c(C(=O)Nc2ccc(N3CCC(COc4cccc(C(=O)O)c4)CC3)nc2)oc2ccc(-c3ccccc3)cc12 CHEMBL2334100 IC50 800.0 nM
CC(C)c1cccc(C(C)C)c1NC(=O)CCCCCSc1nc2cccc(N(C)C)c2o1 CHEMBL4242494 IC50 820.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(Br)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2333811 IC50 830.0 nM
O=C(Nc1ccc(O[C@H]2CC[C@@H](C(=O)O)CC2)c(F)c1)c1nnc(Nc2cc(F)c(F)cc2F)o1 CHEMBL3133016 IC50 860.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccc(Cl)cc3I)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334219 IC50 890.0 nM
Nc1ccc(CC(NC(=O)C(c2ccccc2)c2ccccc2)c2ccccc2)cc1 CHEMBL41233 IC50 900.0 nM
CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1CCC(F)(F)F CHEMBL1257800 IC50 920.0 nM
CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](C[C@H](OC(=O)c3ccc(C#N)cc3)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@H]23)[C@]1(C)COC(=O)c1ccccc1 CHEMBL2375692 IC50 920.0 nM
CCCCCCCN(CCCCCNc1cc(-c2ccccc2)c(-c2ccccc2)nn1)C(=O)Nc1ccc(F)cc1F CHEMBL371677 IC50 940.0 nM
O=C(NCCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)Nc1ccc(F)cc1F CHEMBL4076731 IC50 940.0 nM
O=C(O)C[C@H]1CC[C@@H](Oc2ccc(-c3ccc(-c4nc5cc(Cl)ccc5[nH]4)cn3)cn2)CC1 CHEMBL4453443 IC50 942.0 nM
COc1ccc(C(=O)O[C@H]2C[C@H]3[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@]3(C)[C@H]3[C@@H](O)c4c(cc(-c5cccnc5)oc4=O)O[C@]23C)cc1F CHEMBL2334214 IC50 960.0 nM
O=C(O)C[C@H]1CC[C@@H](Oc2ccc(-c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)cn2)CC1 CHEMBL4452940 IC50 970.0 nM
CC(C)(COc1ccc(-c2ccc(-c3nc4cc(Cl)ccc4[nH]3)cn2)cn1)C(=O)O CHEMBL4585408 IC50 971.0 nM
CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3ccc(F)cc3)cc(N3CCOCC3)nn12 CHEMBL1257679 IC50 990.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccccc3Cl)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334207 IC50 1000.0 nM
CC(=O)OC[C@@]1(C)[C@@H]2C[C@H](OC(=O)c3ccccc3F)[C@@]3(C)Oc4cc(-c5cccnc5)oc(=O)c4[C@H](O)[C@@H]3[C@@]2(C)CC[C@@H]1OC(C)=O CHEMBL2334206 IC50 1000.0 nM
Cc1nc(C)c(-c2ccc(-c3ccc(CC(=O)O)cc3Cl)c(Cl)c2)nc1C(N)=O CHEMBL3133091 pIC50 1000.0 nM