Cc1c(C(=O)N2CCC(C(O)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565940 IC50 1.0 nM
C/C=C(/C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1)C(F)(F)F CHEMBL4539575 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(C#N)CCF)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4518409 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCCCC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554662 IC50 1.0 nM
CCC(C#N)C1(O)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4541433 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(C)C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4526479 IC50 1.0 nM
CCC1(C#N)CC12CCN(C(=O)c1cnn(-c3nn4cccc4c(=O)[nH]3)c1C)CC2 CHEMBL4591533 IC50 1.0 nM
CCC(O)(C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1)C(F)(F)F CHEMBL4550453 IC50 1.0 nM
CCC(C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1)C(F)(F)F CHEMBL4562479 IC50 1.0 nM
Cc1c(C(=O)N2CC3C(C2)C3(C)C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4522277 IC50 1.0 nM
CCC(C#N)C1(F)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4549931 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(=O)N3CCCC3)(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4570174 IC50 1.0 nM
CC[C@H](C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4576651 IC50 1.0 nM
Cc1c(C(=O)N2CC3(C2)CC(F)(F)C3)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4568013 IC50 1.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4543843 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4547958 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3cccnc3F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4530729 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC(F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586926 IC50 1.0 nM
C=CCC(C#N)C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4562897 IC50 1.0 nM
Cc1c(C(=O)N2CCC(S(=O)(=O)C(C)C)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4583036 IC50 1.0 nM
COC1(C)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4567692 IC50 1.0 nM
Cc1c(C(=O)N2CC3CCCC(C2)N3C(=O)OC(C)(C)C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528266 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nccs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536114 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(C)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4590566 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3noc(C4CC4)n3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554154 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C#N)(c3ccccn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4525234 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C3(C#N)CC3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4550973 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C3(C(F)(F)F)CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4560694 IC50 1.0 nM
Cc1c(C(=O)N2CCC(n3cccc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554183 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N(C)C2CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4542770 IC50 1.0 nM
Cc1c(C(=O)N2CC3C(C2)C3(C)C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4578194 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4520652 IC50 1.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)C(C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4531168 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)[C@H](C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553575 IC50 1.0 nM
Cc1c(C(=O)N2C[C@@H]3CCC(F)(F)[C@@H]3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4483610 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)C(C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4558659 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(C#N)C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4516582 IC50 1.0 nM
Cc1c(C(=O)N2CC(N(C)C(=O)OC(C)(C)C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4543041 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(C)C#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4545677 IC50 1.0 nM
Cc1c(C(=O)N2CCC3C(C2)C3C(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4590111 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3ccccn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4575603 IC50 1.0 nM
Cc1c(C(=O)N2CC3CCC(C2)C3(O)C(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4541725 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4538189 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3cccc(Cl)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4590443 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3ccc(C#N)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4575062 IC50 1.0 nM
CCC(C#N)C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4571232 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3ccc(F)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4549178 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CCC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4546206 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)C3(CCC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4540783 IC50 1.0 nM
Cc1c(C(=O)N2CCCC3(CC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539703 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C3(C#N)CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4588476 IC50 1.0 nM
Cc1c(C(=O)N2CC3(C2)CC(F)(F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4569980 IC50 1.0 nM
Cc1c(C(=O)N2CCC(O)(C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4559708 IC50 1.0 nM
Cc1c(C(=O)N2CC3(CCCC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4520726 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CCCC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4593801 IC50 1.0 nM
Cc1c(C(=O)N2CC3CC(F)(F)C3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4525880 IC50 1.0 nM
Cc1c(C(=O)N2CCC(O)(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4519582 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3ccccc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563028 IC50 1.0 nM
Cc1c(C(=O)N2CC3CC(C2)C3(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4520342 IC50 1.0 nM
Cc1c(C(=O)N2C3CCC2CC(O)(c2ccccc2)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565427 IC50 1.0 nM
Cc1c(C(=O)N2CC3CC(F)(F)CC3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4556382 IC50 1.0 nM
Cc1c(C(=O)N2CC3(CCCN3C(=O)OC(C)(C)C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4544256 IC50 1.0 nM
Cc1c(C(=O)N2CCC(OCC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563399 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(C)(O)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4541887 IC50 1.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CCC(C(F)(F)F)CC1 CHEMBL4573411 IC50 1.0 nM
CCOC(=O)c1nnn(-c2nn3cccc3c(=O)[nH]2)c1C CHEMBL4559335 IC50 1.0 nM
CCC1(C#N)CCN(C(=O)c2nnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4530795 IC50 1.0 nM
Cc1c(C(=O)N2CC3(CCN(C(=O)OC(C)(C)C)CC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4570950 IC50 1.0 nM
Cc1c(C(=O)N2CC(c3ccc(F)c(F)c3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4580860 IC50 1.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563700 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C)c3ccccc32)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554274 IC50 1.0 nM
O=C(c1ccn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4579266 IC50 1.0 nM
O=C(c1ccn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4526438 IC50 1.0 nM
CN(C(=O)OC(C)(C)C)[C@@H]1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2)C1 CHEMBL4548342 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528785 IC50 1.0 nM
N#CC1(c2ccccc2)CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2)CC1 CHEMBL4544495 IC50 1.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2)CC1 CHEMBL4531699 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(O)(C(F)(F)F)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4573571 IC50 1.0 nM
CC(C)(C#N)C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2)CC1 CHEMBL4522327 IC50 1.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(CC(F)(F)F)CC1 CHEMBL4576805 IC50 1.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(C2CC2)CC1 CHEMBL4559223 IC50 1.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC2(CC1)CC2 CHEMBL4513401 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C3CC3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4580731 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554981 IC50 1.0 nM
CCC(C#N)(CC)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4548446 IC50 1.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nn4c(F)ccc4c(=O)[nH]3)c2C)CC1 CHEMBL4568171 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)ccn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4540597 IC50 1.0 nM
O=C(c1cnn(-c2nn3c(F)ccc3c(=O)[nH]2)c1C1CC1)N1CCC(C(F)(F)F)CC1 CHEMBL4483011 IC50 1.0 nM
COC(=O)c1cnn(-c2nn3c(F)ccc3c(=O)[nH]2)c1C1CC1 CHEMBL4517548 IC50 1.0 nM
O=C(c1ccc(-c2nc3c(c(=O)[nH]2)CCC3)s1)N1CCC(C(F)(F)F)CC1 CHEMBL4546358 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(C)(C)C#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4576055 IC50 1.0 nM
O=C(c1cnn(-c2nn3c(F)ccc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4550680 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1cc(C(F)(F)F)cc(=O)[nH]1 CHEMBL4574375 IC50 1.0 nM
Cc1cc(-n2ncc(C(=O)N3CCC(C(F)(F)F)CC3)c2C)[nH]c(=O)c1 CHEMBL4576695 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3noc(C(F)(F)F)n3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528515 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nccs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4528416 IC50 1.0 nM
Cc1c(C(=O)N2C3CC2CN(CC(F)(F)F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4558752 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(=O)N3CCC3)(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4591486 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(=O)N3CCCCC3)(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4517775 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(C(N)=O)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4516020 IC50 1.0 nM
Cc1c(C(=O)N2CCC(O)(C3(C#N)CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4561545 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(C#N)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4541950 IC50 1.0 nM
Cc1c(C(=O)N2C3CCC2CN(C2CC2)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4558993 IC50 1.0 nM
C=C(C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1)C(F)(F)F CHEMBL4521463 IC50 1.0 nM
C=C(C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1)C(F)(F)F CHEMBL4566452 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4cccnc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4581966 IC50 1.0 nM
Cc1c(C(=O)N2CCC(CCCF)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4551462 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccccn4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513411 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccccn4)cs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4547790 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccncc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4568872 IC50 1.0 nM
CCC(C#N)C1(F)CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4590041 IC50 1.0 nM
CCC(C#N)C1=CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4552388 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3ccc(F)nc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4584588 IC50 1.0 nM
Cc1c(C(=O)N2CC3CC(C2)N3CC(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4525027 IC50 1.0 nM
Cc1c(C(=O)N2C3CCC2CN(c2nccs2)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565852 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(C(F)(F)F)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4581213 IC50 1.0 nM
Cc1c(C(=O)N2CC3CCCC(C2)C3(O)C(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4592067 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3cccnc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4530620 IC50 1.0 nM
CCC(=O)C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4590215 IC50 1.0 nM
CCC(=O)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4535377 IC50 1.0 nM
Cc1c(C(=O)N2C3CCC2CN(C2CCC2)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4556399 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3ccc(F)cn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4560513 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3ccc(Cl)nc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4588041 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3cccc(F)n3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528369 IC50 1.0 nM
Cc1c(C(=O)N2CCCC(O)(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4583662 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CCC3(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4591311 IC50 1.0 nM
Cc1c(C(=O)N2CC(c3cccc(F)n3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4573576 IC50 1.0 nM
Cc1c(C(=O)N2C3CCC2CC(C(F)(F)F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4543190 IC50 1.0 nM
Cc1c(C(=O)N2CC3CCCC(C2)C3C(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536426 IC50 1.0 nM
Cc1c(C(=O)N2CCCC(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4568332 IC50 1.0 nM
C=C1C2CCCC1CN(C(=O)c1cnn(-c3nn4cccc4c(=O)[nH]3)c1C)C2 CHEMBL4560941 IC50 1.0 nM
Cc1c(C(=O)N2CCC(c3nc(C#N)co3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4589324 IC50 1.0 nM
Cc1c(C(=O)N2CC3CCC(C2)C3C(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4483674 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(C(F)F)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4590315 IC50 1.0 nM
CCC1(C(F)(F)F)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4557455 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(CCF)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563568 IC50 1.0 nM
Cc1c(C(=O)Nc2c(C(C)(O)C(F)(F)F)cnn2C(C)C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554409 IC50 1.0 nM
Cc1c(C(=O)N2CC(c3ccc(F)nc3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4572718 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3nnc(-c4cccnc4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4570595 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4cccnc4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4581833 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4cccnc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565400 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CC(F)(F)C3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4568767 IC50 1.0 nM
Cc1c(C(=O)N2CC3CC(C2)N3C(=O)OC(C)(C)C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536070 IC50 1.0 nM
Cc1c(C(=O)N2CC3CCCC(C2)C3=CC(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4574342 IC50 1.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccncc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4544111 IC50 1.0 nM
Cc1c(C(=O)N2CC(N3CCC(F)(F)C3)C2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4527741 IC50 1.0 nM
Cc1c(C(=O)N2C[C@H]3CCC[C@@H](C2)C3CC(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4568761 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CCC3)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4580351 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CCCC3=O)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4483412 IC50 1.0 nM
COCC(C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1)C(F)(F)F CHEMBL4590828 IC50 1.0 nM
Cc1c(C(=O)N2C[C@H]3CCC[C@@H](C2)[C@@H]3CC(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548349 IC50 1.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)C3(CCC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4567346 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CC3)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4527039 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CCC3(F)F)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4567232 IC50 1.0 nM
Cc1c(C(=O)N2CCc3nc(-c4cccnc4)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563610 IC50 1.0 nM
CCCC(=O)C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4571723 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(=O)C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4549697 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CCC3=O)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586547 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(=O)C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548880 IC50 1.0 nM
CC(=O)C1(c2ccccc2)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4528123 IC50 1.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)c3ccccc32)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4544487 IC50 1.0 nM
Cc1c(C(=O)N2CCC(n3cccc3C#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4535900 IC50 1.0 nM
Cc1c(C(=O)N2CCC3(CCCCC3=O)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554750 IC50 1.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CCN(C2CC2)CC1 CHEMBL4581306 IC50 1.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CCC(C2CC2)CC1 CHEMBL4558607 IC50 1.0 nM
Cc1c(C(=O)N2CC3CC(C2)N3CC(F)(F)F)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4576820 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(=O)CCC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4483582 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(CO)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4580426 IC50 1.0 nM
Cc1c(C(=O)N2CCC(n3ccnc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4546282 IC50 1.0 nM
Cc1c(C(=O)N2CCC(n3cccc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4588585 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CC3C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4572586 IC50 1.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CCN(C2CCC2)CC1 CHEMBL4565006 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CC(F)(F)C3)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4547662 IC50 1.0 nM
Cc1c(C(=O)N2CCC(n3ccc(C#N)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4592760 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C3CCCC3(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4542162 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553846 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)CCC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513705 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccccc3C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4535297 IC50 1.0 nM
CCCS(=O)(=O)N1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4543230 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccccc3F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4556348 IC50 1.0 nM
Cc1nc(C)c(S(=O)(=O)N2CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)s1 CHEMBL4573563 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4564797 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)C3CCCCC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4550161 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccccc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563237 IC50 1.0 nM
Cc1cc(C)c(S(=O)(=O)N2CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)c(C)c1 CHEMBL4582211 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4562941 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc(Cl)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4527183 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc(F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4551686 IC50 1.0 nM
CC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)s1 CHEMBL4590002 IC50 1.0 nM
CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)cc1 CHEMBL4591541 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553500 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4592241 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4593933 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(C#N)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4573125 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc4ccccc34)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4558549 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4577184 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)N(C)C)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4594212 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccccc3C#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4531507 IC50 1.0 nM
Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4586852 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccnc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548304 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cc(Cl)sc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4529488 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563272 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccccc3OC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4582345 IC50 1.0 nM
COC(=O)c1sccc1S(=O)(=O)N1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4540536 IC50 1.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(F)cc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586526 IC50 1.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)c(C(N)=O)nn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4519731 IC50 1.0 nM
Cc1c(C(=O)N2CCN(C(C)C(F)(F)F)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4583955 IC50 1.0 nM
Cc1c(C(=O)N2CCn3cccc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536958 IC50 1.0 nM
Cc1c(C(=O)N2CCC(S(=O)(=O)c3ccccc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4521825 IC50 1.0 nM
Cc1c(C(=O)N2CCC(S(=O)(=O)N3CCCC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513597 IC50 1.0 nM
Cc1c(C(=O)N2CCN(CC3CCCO3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4520912 IC50 1.0 nM
CC[C@@H](C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4560944 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCOCC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528437 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(O)C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4587409 IC50 2.0 nM
CCC(=C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1)C(F)(F)F CHEMBL4562117 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(C#N)CCF)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4516154 IC50 2.0 nM
Cc1c(C(=O)N2CCN(CCC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513612 IC50 2.0 nM
Cc1c(C(=O)N2CCC(F)(C#N)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4534516 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCCCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4536319 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4553620 IC50 2.0 nM
Cc1c(C(=O)N2CC(F)(c3ccccc3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4529606 IC50 2.0 nM
Cc1c(C(=O)N2CC=C(C3(C#N)CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4558334 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C3CC3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4578654 IC50 2.0 nM
Cc1c(C(=O)N2CCN(CC3CCC3)[C@H](C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4575764 IC50 2.0 nM
Cc1c(C(=O)N2CCC(N3CCC(F)(F)CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4557401 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C#N)(CC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4515052 IC50 2.0 nM
Cc1c(C(=O)N2CC3(CCN(CC(F)(F)F)CC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548058 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C3(C(F)(F)F)CC3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4526206 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CN(C(=O)OC(C)(C)C)C3)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4520418 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4584490 IC50 2.0 nM
Cc1c(C(=O)N2CCN(CC#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539567 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@@H]2C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539104 IC50 2.0 nM
CCN1CC2(CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)C1 CHEMBL4524966 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCCC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4574953 IC50 2.0 nM
Cc1c(C(=O)N2C3CCC2CC(F)(F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4514412 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554815 IC50 2.0 nM
Cc1c(C(=O)N2CC(C)(NC(=O)OC(C)(C)C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536845 IC50 2.0 nM
Cc1c(C(=O)N2CCC(NC(=O)OC(C)(C)C)(C(F)(F)F)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4576773 IC50 2.0 nM
Cc1c(C(=O)N2CC[C@H](N(C)C(=O)OC(C)(C)C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4532599 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CCNC3=O)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4526590 IC50 2.0 nM
Cc1c(C(=O)N2CC3CN(c4ccccc4)CC3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4542251 IC50 2.0 nM
Cc1c(C(=O)N2C[C@H]3CN(C(=O)OC(C)(C)C)C[C@H]32)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4562369 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4589315 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3cnccn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4567022 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4588700 IC50 2.0 nM
Cc1c(C(=O)N2CCC(CC#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4582557 IC50 2.0 nM
Cc1c(C(=O)N2CC3(CSC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539735 IC50 2.0 nM
Cc1c(C(=O)N2CC(N3CCC(F)(F)CC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4537431 IC50 2.0 nM
Cc1c(C(=O)N2CC(O)(C3CC3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4547841 IC50 2.0 nM
Cc1c(C(=O)N2CC3C(C2)C3(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4580031 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C)(C#N)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4483640 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC23CCC3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513494 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)OCCO3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4540777 IC50 2.0 nM
Cc1c(C(=O)N2CC3CC2C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539213 IC50 2.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(OCC(F)(F)F)CC1 CHEMBL4541652 IC50 2.0 nM
CCC1(C#N)CCN(C(=O)c2cn(-c3nn4cccc4c(=O)[nH]3)nn2)CC1 CHEMBL4567588 IC50 2.0 nM
CCOC1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2)CC1 CHEMBL4571793 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CN(C(=O)OC(C)(C)C)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539425 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553697 IC50 2.0 nM
Cc1c(C(=O)N2CC3(CCN(C(=O)OC(C)(C)C)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4577048 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4593724 IC50 2.0 nM
O=C(c1cnn(-c2nn3c(F)ccc3c(=O)[nH]2)c1)N1CCC(CC(F)(F)F)CC1 CHEMBL4583784 IC50 2.0 nM
CC1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C2CC2)CC1 CHEMBL4585298 IC50 2.0 nM
O=C(c1cnn(-c2nc3sccc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4592675 IC50 2.0 nM
Cc1c(C(=O)N2C3CCC2CN(C(=O)OC(C)(C)C)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4518292 IC50 2.0 nM
Cc1c(C(=O)N2CC[C@@H](N(C)C(=O)OC(C)(C)C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4534536 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C)c3ccccc32)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4592688 IC50 2.0 nM
Cc1c(C(=O)N2CCC(CC(F)(F)F)CC2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4593923 IC50 2.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(C(O)(C(F)(F)F)C(F)(F)F)CC1 CHEMBL4580107 IC50 2.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(S(=O)(=O)c2ccc(F)c(F)c2)CC1 CHEMBL4559152 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3ccc(F)cc3F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4529043 IC50 2.0 nM
O=C(c1cnn(-c2nc3ccsc3c(=O)[nH]2)c1)N1CCC(CC(F)(F)F)CC1 CHEMBL4551819 IC50 2.0 nM
O=C(c1cnn(-c2nc3ccsc3c(=O)[nH]2)c1)N1CCC(C2CC2)CC1 CHEMBL4591992 IC50 2.0 nM
CC(C)(C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2)CC1 CHEMBL4576808 IC50 2.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(C2CC2)CC1 CHEMBL4586985 IC50 2.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC2(CC1)CC2 CHEMBL4574510 IC50 2.0 nM
Cc1c(C(=O)N2CCC(CC(F)(F)F)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4524429 IC50 2.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(c2c[nH]c3ccccc23)CC1 CHEMBL4539053 IC50 2.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(C(O)(C(F)(F)F)C(F)(F)F)CC1 CHEMBL4552072 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C3CC3)CC2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4550426 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC(F)(F)C3)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4585020 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC(F)(F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513499 IC50 2.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4592388 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cnn1-c1nn2c(F)ccc2c(=O)[nH]1 CHEMBL4568728 IC50 2.0 nM
O=C(c1cnn(-c2nn3cc(F)cc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4541671 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539243 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nn2c(F)ccc2c(=O)[nH]1 CHEMBL4588922 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C#N)(c3ccccc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513856 IC50 2.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4564490 IC50 2.0 nM
CCC(C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4549991 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C#N)(c3ccccc3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4516253 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3ccccc3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4559779 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4515146 IC50 2.0 nM
O=C(c1cnn(-c2nc3ccsc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4577035 IC50 2.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4555021 IC50 2.0 nM
Cc1c(C(=O)N2CC[C@H](C(F)(F)F)C[C@@H]2C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4558387 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C3CC3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4577016 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4581842 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4566891 IC50 2.0 nM
Cc1c(C(=O)N2CCc3ccccc3C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4569741 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4588583 IC50 2.0 nM
Cc1c(C(=O)N2CCc3ccccc3C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4568731 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3noc(C(F)(F)F)n3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4530296 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccccc4)co3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4571049 IC50 2.0 nM
Cc1c(C(=O)N2CC3CCCC(C2)N3CC(F)(F)F)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4483420 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4cccnc4)cs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4549346 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C3(C#N)CCC3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4515982 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3nc(C(N)=O)cs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4588756 IC50 2.0 nM
C=CCC(C#N)(CC=C)C1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4516418 IC50 2.0 nM
Cc1c(C(=O)N2CCCC(F)(F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4592311 IC50 2.0 nM
Cc1c(C(=O)N2CC(c3ccc(F)cn3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4547625 IC50 2.0 nM
Cc1c(C(=O)N2CC(c3cncc(F)c3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4540152 IC50 2.0 nM
Cc1c(C(=O)N2CC(c3ccnc(F)c3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4524984 IC50 2.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccncc4)cs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4560916 IC50 2.0 nM
Cc1c(C(=O)N2CCc3nc(-c4ccccn4)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4567076 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccnc(Cl)c4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4518747 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccc(Cl)nc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4530178 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccc(F)nc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586703 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4cccc(C#N)c4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565031 IC50 2.0 nM
Cc1c(C(=O)N2CCC(C3CC3)CC2)nnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4580863 IC50 2.0 nM
Cc1c(C(=O)N2CC3CC(C2)N3CCC(F)(F)F)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4588839 IC50 2.0 nM
Cc1c(C(=O)N2CC3CC(C2)N3C2CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554523 IC50 2.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccc(C#N)cc4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4589244 IC50 2.0 nM
Cc1c(C(=O)N2CCC(n3ccnc3C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4558249 IC50 2.0 nM
Cc1c(C(=O)N2CCC(n3cnc(C(F)(F)F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4550583 IC50 2.0 nM
Cc1c(C(=O)N2CCC(n3cccc3C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4562359 IC50 2.0 nM
Cc1nn(-c2nn3cccc3c(=O)[nH]2)cc1C(=O)N1CC2(C1)CC(F)(F)C2 CHEMBL4548438 IC50 2.0 nM
Cc1nn(-c2nn3cccc3c(=O)[nH]2)cc1C(=O)N1CCN(C2CCC2)CC1 CHEMBL4536898 IC50 2.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CCN(C2CCC2(F)F)CC1 CHEMBL4584033 IC50 2.0 nM
Cc1c(C(=O)N2CCN(C3CC3F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4576614 IC50 2.0 nM
Cc1c(C(=O)N2CCC(n3ccc(S(=O)(=O)C(F)(F)F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4522829 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)C(C)C)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536062 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc(C#N)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4566238 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554651 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(C(C)(C)C)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513708 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(F)c(Cl)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4550742 IC50 2.0 nM
COc1ccc(S(=O)(=O)N2CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)cc1 CHEMBL4572399 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cc(Cl)c(Cl)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4547971 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc4c(N(C)C)cccc34)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4568805 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528273 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4537562 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc4c(c3)OCO4)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4581008 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(Cl)c(Cl)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4542951 IC50 2.0 nM
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)c3cnn(-c4nn5cccc5c(=O)[nH]4)c3C)CC2)c1 CHEMBL4528971 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc(C(=O)O)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4539713 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(Cl)nc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565734 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(F)cc3F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4530197 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cccc4nsnc34)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4569724 IC50 2.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4536630 IC50 2.0 nM
Cc1c(C(=O)N2CCC(S(C)(=O)=O)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4579140 IC50 2.0 nM
Cc1c(C(=O)N2CC(c3ccnc(C(F)F)c3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528643 IC50 2.0 nM
Cc1c(C(=O)N2CC(c3ccnc(C(F)(F)F)c3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4517168 IC50 2.0 nM
Cc1c(C(=O)N2CC(S(=O)(=O)c3ccccc3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4549254 IC50 2.0 nM
C=CCC(C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4585065 IC50 3.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4547132 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccccc4)cs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4532978 IC50 3.0 nM
Cc1c(C(=O)N2CC(N3CCCC(F)(F)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4571384 IC50 3.0 nM
Cc1c(C(=O)N2CCCN(CC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4541539 IC50 3.0 nM
Cc1c(C(=O)N2CCC3OCCCC3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548521 IC50 3.0 nM
Cc1c(C(=O)N2CCN3CC(F)(F)C[C@H]3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4557608 IC50 3.0 nM
Cc1c(C(=O)N2C[C@@H]3CN(C(=O)OC(C)(C)C)C[C@@H]32)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4550695 IC50 3.0 nM
Cc1c(C(=O)N2C3CCC2CN(c2ccc(C(F)(F)F)cn2)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553749 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3ccc(C#N)cn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4552652 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4562133 IC50 3.0 nM
Cc1c(C(=O)N2CC(N3CCC(F)(F)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4562571 IC50 3.0 nM
Cc1c(C(=O)N2CC3[C@@H](C2)CN3C(=O)OC(C)(C)C)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4537805 IC50 3.0 nM
Cc1c(C(=O)N2CCC3(CC2)COC3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4527308 IC50 3.0 nM
O=C(c1cnn(-c2nc3sccc3c(=O)[nH]2)c1)N1CCC(C2CC2)CC1 CHEMBL4593017 IC50 3.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4571650 IC50 3.0 nM
Cc1c(C(=O)N2CC(c3ccc(F)c(F)c3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4513443 IC50 3.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(CC(F)(F)F)CC1 CHEMBL4543326 IC50 3.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCN(c2ccc(F)cc2F)CC1 CHEMBL4522823 IC50 3.0 nM
Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4555027 IC50 3.0 nM
Cc1c(C(=O)N2CCN3CCC[C@@H]3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4587857 IC50 3.0 nM
Cc1c(C(=O)N2CCCCC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4589508 IC50 3.0 nM
COC(=O)c1cnn(-c2nn3c(F)ccc3c(=O)[nH]2)c1C CHEMBL4569893 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3cccc4[nH]ccc34)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4522114 IC50 3.0 nM
Cc1c(C(=O)N2CCC(S(=O)(=O)c3ccc(F)c(F)c3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4556314 IC50 3.0 nM
Cc1c(C(=O)N2CCC(S(=O)(=O)c3ccc(F)c(F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4515435 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3nc4ccc(F)cc4s3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4582841 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C(C)(C)C)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4570696 IC50 3.0 nM
Cc1c(C(=O)N2CCN3CCC[C@@H]3C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4575445 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4517598 IC50 3.0 nM
Cc1c(C(=O)N2CC[C@@H](N(C)C(=O)OC(C)(C)C)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4557188 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3ccccc3Cl)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4526750 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3ccc(F)cc3F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4590728 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4547921 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nn2cc(F)cc2c(=O)[nH]1 CHEMBL4586692 IC50 3.0 nM
N#CC1(c2ccccc2)CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2)CC1 CHEMBL4560097 IC50 3.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4576731 IC50 3.0 nM
COC1(C)CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4525560 IC50 3.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4514749 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C)(C#N)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4567319 IC50 3.0 nM
O=C(c1cnn(-c2cc3ccsc3c(=O)[nH]2)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4583180 IC50 3.0 nM
Cc1c(C(=O)N2C3CCC2CC(O)(c2ccccc2)C3)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4590719 IC50 3.0 nM
Cc1c(C(=O)N(C)Cc2ccc3ncccc3c2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4581371 IC50 3.0 nM
Cc1c(C(=O)N(CCC#N)C2CCCCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4569348 IC50 3.0 nM
Cc1c(C(=O)N2CCC(CC(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4548494 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C#N)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4542708 IC50 3.0 nM
COC1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4545362 IC50 3.0 nM
Cc1cc(-n2cc(C(=O)N3CCC(C(F)(F)F)CC3)cn2)[nH]c(=O)c1 CHEMBL4577709 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C(C)(O)C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4483335 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4543042 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3ccccc3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4591104 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2C)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4590100 IC50 3.0 nM
Cc1nc(-n2ncc(C(=O)N3CCC(C(F)(F)F)CC3)c2C)[nH]c(=O)c1Cl CHEMBL4577560 IC50 3.0 nM
Cc1c(C(=O)N2CCC(C(C)(C)C)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4582061 IC50 3.0 nM
Cc1c(C(=O)N2CCc3ccccc3C2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4563253 IC50 3.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCC(C(F)(F)F)CC3)c2C)n1 CHEMBL4527333 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3nc(-c4ccccc4)co3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4543576 IC50 3.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4577837 IC50 3.0 nM
Cc1c(C(=O)N2CCC(c3nc(C#N)cs3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4544842 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3nc(C(F)(F)F)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4535622 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3nc(C(F)(F)F)co3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4574708 IC50 3.0 nM
C=C(c1cnn(C(C)C)c1NC(=O)c1cnn(-c2nn3cccc3c(=O)[nH]2)c1C)C(F)(F)F CHEMBL4535244 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3nnc(C(F)(F)F)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4579953 IC50 3.0 nM
Cc1c(C(=O)N2CCc3nc(-c4ccc(F)cc4)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4569590 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccncc4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4577866 IC50 3.0 nM
Cc1c(C(=O)N2CC3CC(C2)N3C2CCC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4562572 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccccc4C#N)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4521129 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccnc(F)c4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4591349 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccc(F)nc4)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4546907 IC50 3.0 nM
Cc1c(C(=O)N2CCCN(C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4519048 IC50 3.0 nM
Cc1c(C(=O)N2CCN(C(=O)C3CC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4585409 IC50 3.0 nM
Cc1c(C(=O)N2CCC2c2cccc(F)n2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4578178 IC50 3.0 nM
Cc1c(C(=O)N2CCCN(C(C)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4576679 IC50 3.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CCN(CC(F)(F)F)CC1 CHEMBL4563180 IC50 3.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccnc(F)c4)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4556390 IC50 3.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CC2(C1)CC(F)(F)C2 CHEMBL4576311 IC50 3.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)Cc3ccccc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4559044 IC50 3.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(C(=O)O)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4546789 IC50 3.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4517046 IC50 3.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cnn(C)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548172 IC50 3.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3ccc(Cl)c(C(F)(F)F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4580496 IC50 3.0 nM
Cc1c(C(=O)N2CCc3[nH]ncc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4529123 IC50 3.0 nM
Cc1c(C(=O)N2CCc3[nH]nc(C(F)(F)F)c3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4579679 IC50 3.0 nM
Cc1c(C(=O)N2CCN(C3COC3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4573952 IC50 3.0 nM
Cc1c(C(=O)N2CC(N3CCC(F)(F)C3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4536749 IC50 4.0 nM
Cc1c(C(=O)N2CC3(CN(CC(F)(F)F)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4575195 IC50 4.0 nM
Cc1c(C(=O)N2CCN3CCC[C@H]3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4555059 IC50 4.0 nM
Cc1c(C(=O)N2CCN(c3ccc(Cl)c(Cl)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4578879 IC50 4.0 nM
Cc1c(C(=O)N2CC3(C2)CC(O)(C(F)(F)F)C3)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4556661 IC50 4.0 nM
Cc1c(C(=O)N2CCN(C)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4520911 IC50 4.0 nM
O=C(c1cnn(-c2nc3sccc3c(=O)[nH]2)c1)N1CCN2CCC[C@@H]2C1 CHEMBL4579782 IC50 4.0 nM
O=C(c1cnn(-c2nc3sccc3c(=O)[nH]2)c1)N1CCC(CC(F)(F)F)CC1 CHEMBL4574282 IC50 4.0 nM
Cc1c(C(=O)N2CCC3(CN(C(=O)OC(C)(C)C)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4532503 IC50 4.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nn4cc(F)cc4c(=O)[nH]3)c2)CC1 CHEMBL4567673 IC50 4.0 nM
Cc1c(C(=O)N2C3CCC2CN(C(=O)OC(C)(C)C)C3)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4537553 IC50 4.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCN2CCC[C@@H]2C1 CHEMBL4579952 IC50 4.0 nM
O=C(c1cnn(-c2nn3cc(F)cc3c(=O)[nH]2)c1)N1CCC(CC(F)(F)F)CC1 CHEMBL4533599 IC50 4.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCN(c2ccc(F)cc2F)CC1 CHEMBL4565618 IC50 4.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(c2nc3ccc(F)cc3s2)CC1 CHEMBL4513525 IC50 4.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCN2CCC[C@@H]2C1 CHEMBL4587731 IC50 4.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3c2nnc(-c3ccccc3)o2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4521467 IC50 4.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3c2nnc(-c3ccccc3)o2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4551115 IC50 4.0 nM
Cc1c(C(=O)N2CCN(C(=O)C34CC(C#N)(C3)C4)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4574628 IC50 4.0 nM
Cc1[nH]c2ccccc2c1C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4575533 IC50 4.0 nM
Cc1c(C(=O)N2CCC(C(O)(C(F)(F)F)C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4538572 IC50 4.0 nM
Cc1c(C(=O)N2CC2c2ccccc2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4571342 IC50 4.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nc4ccsc4c(=O)[nH]3)c2C)CC1 CHEMBL4529632 IC50 4.0 nM
Cc1c(C(=O)N2CCC(C#N)(c3ccccc3)CC2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4559529 IC50 4.0 nM
Cc1c(C(=O)N2CC[C@@H](N(C)C(=O)OC(C)(C)C)C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4537331 IC50 4.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(S(=O)(=O)c2ccccc2)CC1 CHEMBL4533438 IC50 4.0 nM
CC(C)(C#N)C1CCN(C(=O)c2cnn(-c3nc4ccsc4c(=O)[nH]3)c2)CC1 CHEMBL4518029 IC50 4.0 nM
O=C(c1cnn(-c2nc3ccsc3c(=O)[nH]2)c1)N1CCC(S(=O)(=O)c2ccccc2)CC1 CHEMBL4578346 IC50 4.0 nM
Cc1c(C(=O)N2CCCCC2c2cccnc2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4528837 IC50 4.0 nM
Cc1c(C(=O)N2CCC(S(=O)(=O)c3ccccc3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4592449 IC50 4.0 nM
Cc1c(C(=O)N2CCC(O)(c3ccccc3)CC2C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4548577 IC50 4.0 nM
Cc1c(C(=O)N2CCC(C(C)(C)C#N)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4588980 IC50 4.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1C1CC1)N1CCC(C(F)(F)F)CC1 CHEMBL4537305 IC50 4.0 nM
Cc1c(C(=O)N2CC[C@@H](C(F)(F)F)C[C@H]2C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4534636 IC50 4.0 nM
Cc1c(C(=O)N2CCC(F)(F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4548667 IC50 4.0 nM
Cc1c(C(=O)N2[C@H](C)CCC[C@@H]2C)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4515303 IC50 4.0 nM
Cc1c(C(=O)N2CCC(C)CC2C)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4519235 IC50 4.0 nM
Cc1c(C(=O)N2CC(N3CC(C(F)(F)F)C3)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4576081 IC50 4.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4545334 IC50 4.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4cccc(F)c4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4564239 IC50 4.0 nM
Cc1c(C(=O)N2CCCN(CCC(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4514179 IC50 4.0 nM
Cc1c(C(=O)N2CCc3nc(-c4ccncc4)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4588224 IC50 4.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCN2CC(F)(F)C[C@H]2C1 CHEMBL4585780 IC50 4.0 nM
Cc1c(C(=O)N2CCN(S(C)(=O)=O)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4546663 IC50 4.0 nM
CCS(=O)(=O)N1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4552942 IC50 4.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4534799 IC50 4.0 nM
Cc1c(C(=O)N2CCN(S(=O)(=O)c3cnc4ccccc4c3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4573665 IC50 4.0 nM
Cc1c(C(=O)N2CCc3c(c(C(F)(F)F)nn3C)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4561256 IC50 4.0 nM
Cc1c(C(=O)N2CC[C@@H]2c2ccc(F)nc2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4549838 IC50 4.0 nM
Cc1c(C(=O)N2CCN(C(C)(C)C)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553255 IC50 5.0 nM
Cc1c(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586706 IC50 5.0 nM
Cc1c(C(=O)N2CC3CC(=O)CC3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548202 IC50 5.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CC2 CHEMBL4547554 IC50 5.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4528531 IC50 5.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1)N1CCC(c2nc3cc(F)ccc3s2)CC1 CHEMBL4564352 IC50 5.0 nM
Cc1c(C(=O)N2CCCCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4534010 IC50 5.0 nM
Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)cnn1-c1nn2c(F)ccc2c(=O)[nH]1 CHEMBL4575187 IC50 5.0 nM
Cc1c(C(=O)N2CCC3(CCCN3Cc3ccccc3)C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4542716 IC50 5.0 nM
Cc1c(C(=O)N2CCC3(CCCCN3C(=O)OC(C)(C)C)C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4553943 IC50 5.0 nM
CCC1(C#N)CCN(C(=O)c2cnn(-c3nc4sccc4c(=O)[nH]3)c2C)CC1 CHEMBL4541822 IC50 5.0 nM
Cc1c(C(=O)N2CCC(c3ccccc3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4521681 IC50 5.0 nM
Cc1c(C(=O)N2CCC(c3ccccc3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4577806 IC50 5.0 nM
Cc1c(C(=O)N2CCC(Oc3ccccc3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4557631 IC50 5.0 nM
Cc1c(C(=O)N2CCC[C@H](C(F)(F)F)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4586280 IC50 5.0 nM
COC1CN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)C1 CHEMBL4575398 IC50 5.0 nM
Cc1c(C(=O)N2CCC(Oc3ccccc3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4541045 IC50 5.0 nM
Cc1c(C(=O)N2CCCC(C(F)(F)F)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4557883 IC50 5.0 nM
Cc1c(C(=O)N2CC[C@@H](C(F)(F)F)CC2C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4529105 IC50 5.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4558283 IC50 5.0 nM
Cc1nn(-c2nc3ccsc3c(=O)[nH]2)c(C)c1C(=O)N1CCC(C(F)(F)F)CC1 CHEMBL4546353 IC50 5.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3c4ccccc4C[C@@H]3C)c2C)n1 CHEMBL4568167 IC50 5.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCC(C)(C)C3)c2C)n1 CHEMBL4582104 IC50 5.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCN(c4ccccn4)CC3)c2C)n1 CHEMBL4581949 IC50 5.0 nM
Cc1c(C(=O)N2CCC3(CC2)CC3C(=O)N2CCOCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4537050 IC50 5.0 nM
Cc1c(C(=O)N2CCc3nc(C(F)(F)F)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586383 IC50 5.0 nM
Cc1c(C(=O)N2CCc3nc(-c4ccc(Cl)cc4)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4581867 IC50 5.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccccc4F)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528739 IC50 5.0 nM
Cc1c(C(=O)N2CCN(c3nnc(-c4cccc(Cl)c4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4551322 IC50 5.0 nM
Cc1c(C(=O)N2CCc3nc(-c4cccc(Cl)c4)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4554212 IC50 5.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccc(F)cc4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4513256 IC50 5.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccncc4)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4586310 IC50 5.0 nM
Cc1c(C(=O)N2CCC2c2ccc(F)nc2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4545596 IC50 5.0 nM
Cc1c(C(=O)N2CCC2c2cncc(F)c2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4528302 IC50 5.0 nM
Cc1c(C(=O)N2CC(c3ccncc3F)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4542586 IC50 5.0 nM
Cc1c(C(=O)N2CCC2c2ccc(Cl)cc2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4517169 IC50 6.0 nM
Cc1c(C(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4589729 IC50 6.0 nM
Cc1c(C(=O)N2CC3CN(C(=O)OC(C)(C)C)CC3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4538342 IC50 6.0 nM
Cc1c(C(=O)N2CC3CC(C)(O)CC3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4553571 IC50 6.0 nM
Cc1c(C(=O)N2C[C@@H]3CN(C(=O)OC(C)(C)C)[C@@H]3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4564536 IC50 6.0 nM
Cc1c(C(=O)N2CCC(c3nc4cc(F)ccc4s3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4532557 IC50 6.0 nM
Cc1c(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4563409 IC50 6.0 nM
Cc1c(C(=O)N2CCC3OCCCC3C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4576733 IC50 6.0 nM
Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)cnn1-c1nc2sccc2c(=O)[nH]1 CHEMBL4565399 IC50 6.0 nM
Cc1c(C(=O)N2CC(CNC(=O)OC(C)(C)C)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4574087 IC50 6.0 nM
Cc1c(C(=O)N2CCC(c3c[nH]c4cc(F)ccc34)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4513512 IC50 6.0 nM
CC(C)(C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C2CC2)CC1 CHEMBL4542618 IC50 6.0 nM
Cc1c(C(=O)N2CCC3(CCCN3Cc3ccccc3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4586458 IC50 6.0 nM
Cc1c(C(=O)N2CCCCC2=O)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4532856 IC50 6.0 nM
Cc1c(C(=O)N(C)Cc2nnc(-c3ccc(Cl)cc3)o2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4540315 IC50 6.0 nM
Cc1c(C(=O)N2CC(c3ccccc3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4516594 IC50 6.0 nM
COC1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)C1 CHEMBL4561036 IC50 6.0 nM
Cc1c(C(=O)N2CCC(C#N)(c3ccccc3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4577684 IC50 6.0 nM
Cc1nn(-c2nc3ccsc3c(=O)[nH]2)c(C)c1C(=O)N1CCc2ccccc2C1 CHEMBL4586722 IC50 6.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)COC3)c1)N1CCC(C(F)(F)F)CC1 CHEMBL4566102 IC50 6.0 nM
Cc1c(C(=O)N2c3ccccc3C[C@H]2C)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4532294 IC50 6.0 nM
Cc1c(C(=O)N2CCc3ccccc3C2)cnn1-c1nc(C(F)(F)F)cc(=O)[nH]1 CHEMBL4568495 IC50 6.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N(C)Cc3ccccc3)c2C)n1 CHEMBL4541585 IC50 6.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCc4ccccc4C3C)c2C)n1 CHEMBL4542371 IC50 6.0 nM
Cc1nn(-c2nn3cccc3c(=O)[nH]2)cc1C(=O)N1CCN(CC(F)(F)F)CC1 CHEMBL4565118 IC50 6.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4cccc(F)c4)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4525468 IC50 6.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccccc4F)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4548004 IC50 6.0 nM
Cc1c(C(=O)N2CCN(c3nnc(-c4ccccc4Cl)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4530160 IC50 6.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccccc4C#N)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4541466 IC50 6.0 nM
CCC(=O)N1CCN(C(=O)c2cnn(-c3nn4cccc4c(=O)[nH]3)c2C)CC1 CHEMBL4570678 IC50 6.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccnc(Cl)c4)s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4592841 IC50 6.0 nM
Cc1c(C(=O)N2CCN(C(=O)c3ccco3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4551775 IC50 6.0 nM
Cc1c(C(=O)N2C[C@@H]3CCN(C(=O)OC(C)(C)C)C[C@@H]32)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4585132 IC50 7.0 nM
Cc1c(C(=O)N2CCC(c3nc4cc(F)ccc4s3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4529396 IC50 7.0 nM
Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4541978 IC50 7.0 nM
Cc1c(C(=O)N2CCN3CCC[C@@H]3C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4591073 IC50 7.0 nM
Cc1c(C(=O)N2CCC3(CCCCN3C(=O)OC(C)(C)C)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4576469 IC50 7.0 nM
O=C(c1cnn(-c2nn3cccc3c(=O)[nH]2)c1)N1CCC(c2c[nH]c3ccccc23)CC1 CHEMBL4569461 IC50 7.0 nM
COC1(c2ccccc2)CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4571371 IC50 7.0 nM
Cc1c(C(=O)N2CCCC2C(=O)OCc2ccccc2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4570115 IC50 7.0 nM
CCN(Cc1ccccc1)C(=O)c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1C CHEMBL4535480 IC50 7.0 nM
Cc1c(C(=O)N2CCC[C@@H](C(F)(F)F)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4526333 IC50 7.0 nM
Cc1c(C(=O)N2CCCC(Oc3ccccc3)C2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4560669 IC50 7.0 nM
Cc1c(C(=O)N2CCC(O)(c3ccccc3)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4539408 IC50 7.0 nM
CCC1Cc2ccccc2N1C(=O)c1cnn(-c2nc(C)cc(=O)[nH]2)c1C CHEMBL4587658 IC50 7.0 nM
Cc1c(C(=O)N2CCC(C)(C)C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4557784 IC50 7.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCc4ccccc4[C@H]3C)c2C)n1 CHEMBL4565548 IC50 7.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCc4ccc(S(=O)(=O)N5CCOCC5)cc4C3)c2C)n1 CHEMBL4541305 IC50 7.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3c4ccccc4CC3C)c2C)n1 CHEMBL4585922 IC50 7.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCc4ccccc4C3)c2C)n1 CHEMBL4569961 IC50 7.0 nM
Cc1c(C(=O)N2CCc3nc(-c4ccccc4Cl)sc3C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4537601 IC50 7.0 nM
Cc1c(C(=O)N2CCN(c3nnc(-c4cccc(F)c4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4519765 IC50 7.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CC2CC(C1)N2CC(F)(F)F CHEMBL4539632 IC50 7.0 nM
Cc1c(C(=O)N2CC[C@H]2c2ccc(F)nc2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4546853 IC50 7.0 nM
O=c1[nH]c(SCc2cccc(Br)c2)nc2c1CCC2 CHEMBL4572878 Kd 7.0 nM
Cc1c(C(=O)N2C[C@@H]3C[C@H]2CN3Cc2ccccc2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4551929 IC50 8.0 nM
CCOC(=O)c1cn(-c2nn3cccc3c(=O)[nH]2)nn1 CHEMBL4547779 IC50 8.0 nM
Cc1c(C(=O)N2CC(F)(F)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4579237 IC50 8.0 nM
Cc1c(C(=O)N2CCC(CC(F)(F)F)CC2)cnn1-c1nn2cc(F)cc2c(=O)[nH]1 CHEMBL4562644 IC50 8.0 nM
CC(C#N)C1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C2CC2)CC1 CHEMBL4586754 IC50 8.0 nM
Cc1c(C(=O)N2CCC3OCCCC3C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4531069 IC50 8.0 nM
Cc1c(C(=O)N2CCC(OCC(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4548170 IC50 8.0 nM
Cc1c(C(=O)N(C)C2CCCCC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4527937 IC50 8.0 nM
Cc1c(C(=O)N2Cc3ccccc3C[C@H]2C(=O)NC(C)(C)C)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4553983 IC50 8.0 nM
COC1CCCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)C1 CHEMBL4524252 IC50 8.0 nM
Cc1nc(-n2ncc(C(=O)N3CCc4ccccc4C3)c2C)[nH]c(=O)c1Cl CHEMBL4521231 IC50 8.0 nM
CCCN(C)C(=O)c1cnn(-c2nc(C)cc(=O)[nH]2)c1C CHEMBL4518338 IC50 8.0 nM
Cc1c(C(=O)N2CCN(c3nnc(-c4ccc(Cl)cc4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4529813 IC50 8.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4ccccc4Cl)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4569895 IC50 8.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccccc4Cl)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4520900 IC50 8.0 nM
Cc1c(C(=O)N2CCN(c3nc(-c4ccccc4C(F)(F)F)cs3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4565885 IC50 8.0 nM
Cc1c(C(=O)N2CCC(n3cccc3S(=O)(=O)C(F)(F)F)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4567045 IC50 8.0 nM
O=C(c1cnn(-c2nc3sccc3c(=O)[nH]2)c1)N1CCC(c2c[nH]c3ccccc23)CC1 CHEMBL4542146 IC50 9.0 nM
Cc1c(C(=O)N2CCN(C(=O)C34CC(C(N)=O)(C3)C4)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4534209 IC50 9.0 nM
Cc1c(C(=O)N2CCN(C(=O)C34CC(C(=O)O)(C3)C4)CC2)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4580645 IC50 9.0 nM
O=C(c1cnn(-c2nc3c(c(=O)[nH]2)CCC3)c1C1CC1)N1CCC(c2nc3ccccc3s2)CC1 CHEMBL4577598 IC50 9.0 nM
Cc1ccc(C2(C)CN(C(=O)c3cnn(-c4nc5c(c(=O)[nH]4)CCC5)c3C)CCO2)cc1 CHEMBL4528815 IC50 9.0 nM
Cc1c(C(=O)N(C)CCc2c[nH]c3ccccc23)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4589069 IC50 9.0 nM
Cc1ccccc1N1CCN(C(=O)c2cnn(-c3nc4c(c(=O)[nH]3)CCC4)c2C)CC1 CHEMBL4572563 IC50 9.0 nM
Cc1c(C(=O)N2CCC(C)CC2C(F)(F)F)cnn1-c1nc2c(c(=O)[nH]1)CCC2 CHEMBL4524335 IC50 9.0 nM
Cc1cc(=O)[nH]c(-n2cc(C(=O)N3CCC(C(F)(F)F)CC3)cn2)n1 CHEMBL4584077 IC50 9.0 nM
Cc1cc(-n2cc(C(=O)N3CCC(C(F)(F)F)CC3)c(C)n2)[nH]c(=O)c1 CHEMBL4557943 IC50 9.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)CC2)cnn1-c1nc2[nH]ccc2c(=O)[nH]1 CHEMBL4570831 IC50 9.0 nM
Cc1c(C(=O)N2CCCCC2(C)C)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4570373 IC50 9.0 nM
Cc1nn(-c2nc3ccsc3c(=O)[nH]2)c(C)c1C(=O)N1CCC(C)(C)C1 CHEMBL4530897 IC50 9.0 nM
Cc1c(C(=O)N2CCC(C(F)(F)F)C2)cnn1-c1nc2ccsc2c(=O)[nH]1 CHEMBL4589966 IC50 9.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N(C)C3CCc4ccccc43)c2C)n1 CHEMBL4543286 IC50 9.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCc4ccccc4[C@@H]3C)c2C)n1 CHEMBL4534690 IC50 9.0 nM
COc1ccc2c(c1)CN(C(=O)c1cnn(-c3nc(C)cc(=O)[nH]3)c1C)CC2 CHEMBL4525274 IC50 9.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3Cc4ccccc4C3)c2C)n1 CHEMBL4593479 IC50 9.0 nM
Cc1cc(=O)[nH]c(-n2ncc(C(=O)N3CCC4(CCOCC4)C3)c2C)n1 CHEMBL4535098 IC50 9.0 nM
Cc1c(C(=O)N2CCN(c3ncc(-c4cccc(Cl)c4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4579941 IC50 9.0 nM
Cc1c(C(=O)NC2CC(F)(F)C2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4561724 IC50 9.0 nM
Cc1c(C(=O)N2CCN(c3nnc(-c4ccc(C(F)(F)F)cn4)o3)CC2)cnn1-c1nn2cccc2c(=O)[nH]1 CHEMBL4591534 IC50 9.0 nM
O=C(c1cn(-c2nn3cccc3c(=O)[nH]2)nn1)N1CC(N2CCC(F)(F)C2)C1 CHEMBL4593602 IC50 9.0 nM
Cc1c(C(=O)N2CCN(CC(F)(F)F)CC2)cnn1-c1nc2c(c(=O)[nH]1)COC2 CHEMBL4593821 IC50 9.0 nM