COc1nc2c(c(-c3ccccc3)c1C#N)Cc1ccccc1-2 CHEMBL5082385 IC50 2.1 nM
C=CCOc1nc(-c2ccccn2)cc(-c2ccc(F)cc2)c1C#N CHEMBL5075881 IC50 5.5 nM
COc1nc(-c2ncccc2C)cc(-c2ccc(F)cc2)c1C#N CHEMBL5079537 IC50 8.7 nM
CCOc1nc2c(c(-c3ccc(F)cc3)c1C#N)Cc1ccccc1-2 CHEMBL5080702 IC50 9.4 nM
COc1nc(-c2ccccn2)cc(-c2ccc(F)cc2)c1C#N CHEMBL5078297 IC50 14.0 nM
COc1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C#N CHEMBL5074290 IC50 25.0 nM
COc1nc(-c2ncccc2C)cc(-c2ccc(N)cc2)c1C#N CHEMBL5088404 IC50 29.0 nM
CCOC(=O)COc1nc(-c2ccccc2)cc(-c2ccccc2)c1C#N CHEMBL5078802 IC50 30.0 nM
Cc1cccnc1-c1cc(-c2ccc(F)cc2)c(C#N)c(OCc2cccnc2)n1 CHEMBL5081359 IC50 36.0 nM
Cc1cccnc1-c1cc(-c2ccc(F)cc2)c(C#N)c(OCCN2CCN(C(=O)OC(C)(C)C)CC2)n1 CHEMBL5092002 IC50 43.0 nM
COc1nc(-c2ccccc2)cc(-c2ccccc2)c1C#N CHEMBL5085735 IC50 53.0 nM
COc1ccccc1-c1cc(-c2ccc(F)cc2)c(C#N)c(OC)n1 CHEMBL5078095 IC50 75.0 nM
N#Cc1c(-c2ccccc2)cc(-c2ccccc2)nc1OCc1ccccc1 CHEMBL5080718 IC50 100.0 nM
COc1cccc(-c2cc(-c3ccc(F)cc3)c(C#N)c(OC)n2)c1 CHEMBL5078475 IC50 108.0 nM
CCOc1nc(-c2ccccc2)nc(-c2ccccc2)c1C#N CHEMBL5089512 IC50 121.0 nM
COCCOc1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C#N CHEMBL5084456 IC50 123.0 nM
CCSc1nc(-c2ccccc2)cc(-c2ccccc2)c1C#N CHEMBL5077205 IC50 132.0 nM
COc1nc(C(C)(C)C)cc(-c2ccc(F)cc2)c1C#N CHEMBL5084987 IC50 153.0 nM
COc1nc(-c2cccnc2)cc(-c2ccc(F)cc2)c1C#N CHEMBL5077063 IC50 213.0 nM
COc1nc(-c2ccccc2)cc(-c2ccc(Cl)cc2)c1C#N CHEMBL5088677 IC50 252.0 nM
COc1nc(-c2ccccc2)cc(-c2ccccc2)c1C CHEMBL5074864 IC50 437.0 nM
COc1nc(-c2ccccc2)cc(-c2ccncc2)c1C#N CHEMBL5079117 IC50 541.0 nM
COc1nc(-c2ccccn2)cc(C(C)(C)C)c1C#N CHEMBL5084810 IC50 850.0 nM