C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1c(Cl)cccc1C(F)(F)F CHEMBL86832 Ki 0.13 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)Nc3cc(C(F)(F)F)ccc3C(F)(F)F)[C@@]2(C)CCC1=O CHEMBL25183 Ki 0.2 nM
C[C@]12CCC(=O)C(Cl)=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)ccc1C(F)(F)F CHEMBL282037 Ki 0.2 nM
C[C@]12CC[C@H]3[C@@H](CNC4=C(Cl)C(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)Nc1c(C(F)(F)F)cccc1C(F)(F)F CHEMBL2115222 Ki 0.2 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)Nc3c(C(F)(F)F)cccc3C(F)(F)F)[C@@]2(C)CCC1=O CHEMBL445627 Ki 0.2 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)N(c3ccc(Cl)cc3)C3CCCC3)[C@@]2(C)CCC1=O CHEMBL283123 Ki 0.3 nM
COc1ccc(CCC(=O)c2c(O)cc(O[C@@H]3O[C@](C)(CO)[C@@](C)(O)[C@](C)(O)[C@@]3(C)O[C@]3(C)OC(C)(C)[C@](C)(O)[C@@](C)(O)[C@H]3O)cc2O)cc1O CHEMBL1159458 Ki 0.4 nM
CC(C)CCCC(C)[C@H]1CCC2C3C(CC[C@@]21C)[C@@]1(C)CCC(=O)N(C)C1C[C@@H]3C CHEMBL25448 IC50 0.5 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)Nc3c(C(C)(C)C)cccc3C(F)(F)F)[C@@]2(C)CCC1=O CHEMBL421735 Ki 0.5 nM
C[C@]12CCC(=O)C(Cl)=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N(c1ccc(Cl)cc1)C1CCCC1 CHEMBL283430 Ki 0.6 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)N(C)C1=C[C@@H]3C CHEMBL421627 IC50 0.6 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC1(c2ccc(Cl)cc2)CCCC1 CHEMBL420415 IC50 0.9 nM
CCCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL275153 IC50 0.91 nM
CCCCCCCCC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL307745 Ki 1.0 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC34CC5CC(CC(C5)C3)C4)[C@@]2(C)CCC1=O CHEMBL306289 Ki 1.1 nM
CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)c(NC(=O)[C@H]3CCC4C5CNC6=CC(=O)CC[C@]6(C)C5CC[C@@]43C)c2)cc1 CHEMBL87805 Ki 1.3 nM
CC(C)(C)c1ccc(C2(NC(=O)[C@H]3CCC4C5CNC6=CC(=O)CC[C@]6(C)C5CC[C@@]43C)CCCCC2)cc1 CHEMBL88032 Ki 1.5 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)C=CC(=O)NC1C[C@@H]3C CHEMBL126686 IC50 1.6 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2298601 IC50 1.7 nM
CC(C)CCCC(C)[C@H]1CCC2C3CCC4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL24193 IC50 1.7 nM
CC(C)CCCC(C)C1CCC2C3CCC4N(C)C(=O)CC[C@]4(C)C3CC[C@]12C CHEMBL340027 IC50 1.7 nM
CCCCCN(C(=O)CCCC)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL280015 IC50 1.77 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)C=CC(=O)N(C)C1C[C@@H]3C CHEMBL128023 IC50 2.0 nM
COc1ccc(N(C(=O)c2ccccc2)[C@H]2CCC3C4CC[C@H]5N(C)C(=O)CC[C@]5(C)C4CC[C@@]32C)cc1 CHEMBL17245 IC50 2.11 nM
CC(C)CCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17222 IC50 2.19 nM
CN1C(=O)CC[C@@H]2c3ccc(Cl)cc3CC[C@H]21 CHEMBL24955 IC50 2.3 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4N(C=O)CCC(C)(C)C)C3CC[C@@H]12 CHEMBL16863 IC50 2.35 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)ccc1C(F)(F)F CHEMBL283245 IC50 2.4 nM
CCCCCN(C(=O)CCCCBr)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL274269 IC50 2.42 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)NC1=C[C@@H]3C CHEMBL338376 IC50 2.5 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)NC1C[C@@H]3C CHEMBL340715 IC50 2.6 nM
CC(C)CCCC(C)C1CCC2C3CCC4NC(=O)CC[C@]4(C)C3CC[C@]12C CHEMBL340181 IC50 2.6 nM
CC1=C2CCc3cc(Cl)ccc3N2CCC1=O CHEMBL118446 Ki 2.7 nM
CC[C@H]1CC2NC(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL340684 IC50 2.7 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4N(C(=O)c4ccccc4)c4ccccc4)C3CC[C@@H]12 CHEMBL276320 IC50 2.93 nM
CC(C)Cc1ccc(C(Nc2cccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)c2)c2ccc(CC(C)C)cc2)cc1 CHEMBL25083 IC50 3.0 nM
CC(C)(C)c1ccc(C2(NC(=O)[C@H]3CCC4C5CNC6=CC(=O)CC[C@]6(C)C5CC[C@@]43C)CCCC2)cc1 CHEMBL314309 Ki 3.0 nM
CCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL277053 IC50 3.05 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC1(c2ccc(Cl)cc2)CCCCC1 CHEMBL90440 Ki 3.1 nM
CC(C)CC(=O)[C@H]1CCC2C3CN(C)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL80160 Ki 3.1 nM
CC(C)CC(=O)[C@H]1CCC2C3CNC4=C(Br)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL311045 Ki 3.2 nM
CCCCCN(C(=O)c1ccccc1)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL16784 IC50 3.22 nM
CCN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4C(C)CCCC(C)C)C3[C@@H](C)CC12 CHEMBL24958 IC50 3.3 nM
CCN1C(=O)CC[C@]2(C)C3CC[C@]4(C)C(C(C)CCCC(C)C)CCC4C3[C@@H](C)CC12 CHEMBL340305 IC50 3.3 nM
CCCCCN(C(=O)CCC)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL278490 IC50 3.31 nM
CC(C)(C)c1ccc(-c2ccc(Cl)cc2)cc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL328670 Ki 3.4 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4cnc5ccccc5c4)cc3CC[C@@H]12 CHEMBL130845 IC50 3.4 nM
CC(C)(C)c1ccc(C2(NC(=O)[C@H]3CCC4C5CNC6=CC(=O)CC[C@]6(C)C5CC[C@@]43C)CCCCCC2)cc1 CHEMBL88485 Ki 3.6 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC(c3ccccc3)c3ccccc3)[C@@]2(C)CCC1=O CHEMBL77290 Ki 3.6 nM
C[C@]12C=CC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)NC(c3ccccc3)(C(F)(F)F)C(F)(F)F)CC[C@@H]12 CHEMBL4569322 IC50 3.9 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)ccc1C(F)(F)F CHEMBL327702 Ki 4.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)CC1CCCCC1 CHEMBL430617 Ki 4.0 nM
C[C@]12C=CC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)Nc3cc(C(F)(F)F)ccc3C(F)(F)F)CC[C@@H]12 CHEMBL1200969 IC50 4.0 nM
CC(C)(C)c1ccc(Br)cc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL314725 Ki 4.2 nM
CC(C)CCCC(C)C1CCC2C3CC=C4N(C)C(=O)CC[C@]4(C)C3CC[C@]12C CHEMBL125855 IC50 4.3 nM
C[C@]12CCC(=O)C(Br)=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC12CC3CC(CC(C3)C1)C2 CHEMBL305855 Ki 4.5 nM
CCCCCN(C(=O)CC)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17194 IC50 4.56 nM
CC(C)(C)c1ccc(-c2ccccc2)cc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL87082 Ki 4.6 nM
CC(C)(C)c1ccc(C(C)(C)C)c(NC(=O)[C@H]2CCC3C4CNC5=CC(=O)CC[C@]5(C)C4CC[C@@]32C)c1 CHEMBL89327 Ki 5.0 nM
CC(C)CCCC(C)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C CHEMBL338207 IC50 5.0 nM
CCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL274276 IC50 5.08 nM
CC(C)(C)c1cc(Br)ccc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL314977 Ki 5.3 nM
COc1ccc(N(C(=O)C(C)C)[C@H]2CCC3C4CC[C@H]5N(C)C(=O)CC[C@]5(C)C4CC[C@@]32C)cc1 CHEMBL16700 IC50 5.44 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1ccccc1C(F)(F)F CHEMBL278787 IC50 5.6 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3C(F)(F)F)CCC12 CHEMBL110288 IC50 5.6 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4N(C=O)Cc4ccccc4)C3CC[C@@H]12 CHEMBL276527 IC50 5.63 nM
CC[C@H]1CC2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL127702 IC50 5.7 nM
CC1=C2CCc3cc(C)ccc3N2CCC1=O CHEMBL118319 Ki 5.8 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cc(C(F)(F)F)ccc3C(F)(F)F)CCC12 CHEMBL108559 IC50 5.8 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C\c4ccccc4)cc3CC[C@@H]12 CHEMBL129017 IC50 6.0 nM
CC1=C2N(C)CC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC34CC5CC(CC(C5)C3)C4)[C@@]2(C)CCC1=O CHEMBL307398 Ki 6.2 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(c2ccccc2)c2ccccc2)[C@@]2(C)CCC(=O)C=C12 CHEMBL306554 Ki 6.4 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC1(c2ccc(Cl)cc2Cl)CC1 CHEMBL89557 Ki 6.7 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(Cl)cc3)CCC12 CHEMBL109170 IC50 6.8 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC1(c2ccc(Cl)cc2)CCCC1 CHEMBL314953 Ki 6.8 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 CHEMBL3085538 Ki 6.9 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 CHEMBL138173 Ki 6.9 nM
CCCCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17506 IC50 7.25 nM
CC(C)CN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL16690 IC50 7.31 nM
CC(C)(C)c1ccc(Cl)cc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL87021 Ki 7.5 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3F)CCC12 CHEMBL111476 IC50 7.9 nM
CN1C(=O)CCC2c3ccc(Cl)cc3CCC21 CHEMBL279131 Log 1/IC50 7.943 nM
CCCc1ccc(OC(C)c2ccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)cc2)cc1 CHEMBL279745 IC50 8.0 nM
CC(C)(C)c1cc(NC(=O)[C@H]2CCC3C4CNC5=CC(=O)CC[C@]5(C)C4CC[C@@]32C)cc(C(C)(C)C)c1 CHEMBL25516 Ki 8.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cccc2ccccc12 CHEMBL285599 IC50 8.1 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc4ccccc34)CCC12 CHEMBL107654 IC50 8.1 nM
CC1=C2CCc3cc(Br)ccc3N2CCC1=O CHEMBL116999 IC50 8.1 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL308258 Ki 8.2 nM
CCC[C@H]1C=C2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL125209 IC50 8.4 nM
CC1=C2CC(C)c3cc(Cl)ccc3N2CCC1=O CHEMBL125256 IC50 8.5 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@]2(C)CCC(=O)C=C12 CHEMBL310711 Ki 8.5 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@]2(C)CCC(=O)C(Br)=C12 CHEMBL76260 Ki 8.6 nM
CC[C@H]1C=C2NC(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL332781 IC50 8.6 nM
CC1=C2CCc3cc(C#Cc4ccccc4)ccc3N2CCC1=O CHEMBL117159 Log IC50 8.71 nM
CC(C)(C)c1ccc(C(F)(F)F)cc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL277224 Ki 8.8 nM
CN1C(=O)CC[C@]2(C)c3ccc(Cl)cc3CCC12 CHEMBL417109 Ki 9.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(Cl)cc3CC[C@@H]12 CHEMBL29166 Ki app 9.0 nM
CC(C)CC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL420020 Ki app 9.0 nM
CCC[C@H]1CC2NC(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL414427 IC50 9.5 nM
CC[C@H]1C=C2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL125260 IC50 9.5 nM
CC(C)N(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17268 IC50 9.53 nM
CCCCCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17206 IC50 9.57 nM
Cc1c(C(=O)c2ccc3c(c2)OC(c2ccc(Cl)cc2)(c2ccc(Cl)cc2)O3)c2ccccc2n1CCCC(=O)O CHEMBL285439 IC50 10.0 nM
CC(C)C(=O)N(c1ccccc1)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL266519 IC50 10.5 nM
CCC(CC)N(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL16533 IC50 10.6 nM
Cc1ccc2c(c1)CC[C@@H]1[C@@H]2CCC(=O)N1C CHEMBL134357 IC50 11.0 nM
COc1ccccc1NC(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C CHEMBL108305 IC50 11.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC12CC3CC(CC(C3)C1)C2 CHEMBL77024 Ki 11.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL137733 Ki 11.0 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4N(C=O)C4CC4)C3CC[C@@H]12 CHEMBL276355 IC50 11.2 nM
CCCCN(C(C)=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17514 IC50 11.8 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4N(C=O)C4CCCCC4)C3CC[C@@H]12 CHEMBL16927 IC50 11.9 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(C(=O)c4ccccc4)c3)CCC12 CHEMBL323031 IC50 12.0 nM
CCCC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL311577 Ki 12.0 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC(C)(C)C)[C@@]2(C)CCC1=O CHEMBL78275 Ki 12.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(C(F)(F)F)c3)CCC12 CHEMBL432439 IC50 12.5 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3O)CCC12 CHEMBL109232 IC50 12.9 nM
CC(=O)N1N=C(C2=CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)C[C@H]1c1ccc(F)cc1 CHEMBL5182135 IC50 13.9 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cccc(-c2ccccc2)c1 CHEMBL264316 IC50 14.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(-c4ccccc4)c3)CCC12 CHEMBL322749 IC50 14.0 nM
Cc1cccc(C)c1NC(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C CHEMBL108181 IC50 14.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NN(c1ccccc1)c1ccccc1 CHEMBL312531 Ki 14.0 nM
CCc1ccc2c(c1)CCC1=C(C)C(=O)CCN12 CHEMBL120310 IC50 14.0 nM
CC1=C2CCc3cc(/C=C\c4ccccc4)ccc3N2CCC1=O CHEMBL119259 Log IC50 14.13 nM
C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3ccn(-c4ccc(Cl)cc4)n3)=CC[C@@H]12 CHEMBL5188574 IC50 14.2 nM
C[C@@H]1CC2=CC(=O)CCN2c2ccc(Cl)cc21 CHEMBL118573 IC50 14.4 nM
CC1CC2=CC(=O)CCN2c2ccc(Cl)cc21 CHEMBL122290 IC50 14.4 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3Cl)CCC12 CHEMBL108028 IC50 14.5 nM
CN1C(=O)CC[C@@H]2c3ccc(Cl)cc3CC[C@@H]21 CHEMBL281204 Ki app 15.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)c1cccc2ccccc12 CHEMBL76637 Ki 15.0 nM
CC1=C2C(C)Cc3cc(Cl)ccc3N2CCC1=O CHEMBL125442 IC50 15.6 nM
CC1=C2CC(C)c3cc(C)ccc3N2CCC1=O CHEMBL125257 IC50 15.8 nM
CC(NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C)(c1ccccc1)C(F)(F)F CHEMBL4540042 IC50 16.0 nM
CCCCCCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL417627 IC50 16.9 nM
CN1C(=O)CCC2=C1CCc1cc(Cl)ccc12 CHEMBL16456 Ki app 17.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc4ccccc4c3)CCC12 CHEMBL107719 IC50 17.2 nM
Cc1ccc(NC(=O)C2CCC3C4CCC5NC(=O)C=C[C@]5(C)C4CC[C@]23C)cc1 CHEMBL322592 IC50 17.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(Cl)c3)CCC12 CHEMBL108625 IC50 18.2 nM
COc1cccc(NC(=O)C2CCC3C4CCC5NC(=O)C=C[C@]5(C)C4CC[C@]23C)c1 CHEMBL108875 IC50 19.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(C(=O)c4ccccc4)cc3)CCC12 CHEMBL110058 IC50 19.0 nM
CC(C)CCCC(C)[C@H]1CCC2C3CC=C4NC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL283508 IC50 19.1 nM
CC(C)CCCC(C)C1CCC2C3CC=C4NC(=O)CC[C@]4(C)C3CC[C@]12C CHEMBL338707 IC50 19.1 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1ccccc1 CHEMBL25664 IC50 20.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1 CHEMBL412425 Ki 20.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3)CCC12 CHEMBL324210 IC50 20.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL306722 Ki 20.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(C1CCCCC1)C1CCCCC1 CHEMBL77328 Ki 20.0 nM
CCC[C@H]1CC2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL126968 IC50 20.0 nM
CN1C(=O)CCC2(C)c3ccc(Cl)cc3CCC12 CHEMBL279417 Ki app 20.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(Br)c3)CCC12 CHEMBL110398 IC50 20.5 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(C(F)(F)F)cc3)CCC12 CHEMBL323033 IC50 20.9 nM
CN1C(=O)CC[C@]2(C)c3ccc(C#Cc4ccccc4)cc3CC[C@@H]12 CHEMBL128303 IC50 21.0 nM
C=Cc1ccc2c(c1)CCC1=C(C)C(=O)CCN12 CHEMBL116493 Log IC50 21.38 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(F)cc3)CCC12 CHEMBL321617 IC50 22.5 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4ccccc4)cc3CC[C@@H]12 CHEMBL300446 IC50 23.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(F)c3)CCC12 CHEMBL323788 IC50 23.0 nM
O=C(O)CCCn1cc(C(=O)c2ccc3c(c2)OC(c2ccccc2)(c2ccccc2)O3)c2ccccc21 CHEMBL287906 Potency 23.0 nM
Cc1cccc(NC(=O)C2CCC3C4CCC5NC(=O)C=C[C@]5(C)C4CC[C@]23C)c1 CHEMBL108151 IC50 24.6 nM
CC(C)Cc1ccc([C@]2(C)Oc3ccc(C(=O)c4cn(CCCC(=O)O)c5ccccc45)cc3O2)cc1 CHEMBL279206 IC50 25.0 nM
O=C(O)c1ccc2c(c1)CCc1cc(Br)ccc1-2 CHEMBL25578 IC50 26.0 nM
COc1ccc(NC(=O)C2CCC3C4CCC5NC(=O)C=C[C@]5(C)C4CC[C@]23C)cc1 CHEMBL411431 IC50 26.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL89240 Ki 26.0 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL710 IC50 26.3 nM
CC(C)(C)c1ccccc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL88494 Ki 27.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3C(=O)c3ccccc3)CCC12 CHEMBL325572 IC50 28.7 nM
CN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17193 IC50 29.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL24088 Ki 30.0 nM
Cc1ccccc1NC(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C CHEMBL107565 IC50 30.3 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4ccc5ccccc5n4)cc3CC[C@@H]12 CHEMBL341004 IC50 32.0 nM
Cc1ccc2c(c1)CCC1C2CCC(=O)N1C CHEMBL15917 Log 1/IC50 32.36 nM
Cc1ccc2c(c1)CCC1=C2CCC(=O)N1C CHEMBL279420 Log 1/IC50 32.36 nM
CC(C)C(=O)N(c1ccc([N+](=O)[O-])cc1)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17473 IC50 32.8 nM
CN1C(=O)CCC2c3ccc(F)cc3CCC21 CHEMBL278957 Log 1/IC50 34.67 nM
CN1C(=O)CCC2c3ccc(Br)cc3CCC21 CHEMBL278981 Log 1/IC50 34.67 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(-c4ccccc4)cc3)CCC12 CHEMBL109089 IC50 34.9 nM
CN1C(=O)CC[C@@H]2c3ccc(F)cc3CC[C@H]21 CHEMBL424084 IC50 35.0 nM
CC(C)(C)N(O)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL78064 Ki 38.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3-c3ccccc3)CCC12 CHEMBL111142 IC50 38.3 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)c1c(F)cccc1F CHEMBL306781 Ki 39.0 nM
CC(C)Cc1ccc([C@H](C)Oc2ccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)cc2)cc1 CHEMBL25193 IC50 40.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL77765 Ki 40.0 nM
C=CCN1C(=O)CC[C@]2(C)C3CC[C@]4(C)C(C(C)CCCC(C)C)CCC4C3[C@@H](C)CC12 CHEMBL127760 IC50 42.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccccc4C(F)(F)F)ccc3N2CCC1=O CHEMBL183167 IC50 42.0 nM
C[C@]12C=CC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL3706581 Ki 48.0 nM
O=C1C=C2CCc3cc(Cl)ccc3N2CC1 CHEMBL326743 Log IC50 48.98 nM
O=C(O)CCCOc1ccccc1-c1cc2ccc(C(=O)NC(c3ccc(F)cc3)c3ccc(F)cc3)cc2o1 CHEMBL153258 IC50 50.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(Cl)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL432729 Ki 51.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(O)c3)CCC12 CHEMBL109560 IC50 52.0 nM
CCC[C@H]1C=C2NC(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL124750 IC50 58.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(-c4ccco4)cc3CC[C@@H]12 CHEMBL131341 IC50 59.0 nM
CC(C)C(=O)N(c1ccc([N+](=O)[O-])c(C(F)(F)F)c1)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17422 IC50 59.8 nM
O=C1CC[C@@H]2c3ccc(Cl)cc3CC[C@H]2N1 CHEMBL134810 IC50 60.0 nM
C[C@]12CCC(C(=O)O)=CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC1(c2ccc(Cl)cc2)CCCC1 CHEMBL86418 IC50 60.0 nM
CC1=C2N(C)CC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC(C)(C)C)[C@@]2(C)CCC1=O CHEMBL75320 Ki 60.0 nM
CN1C(=O)CCC2=C1CCc1cc(Br)ccc12 CHEMBL16494 Log 1/IC50 60.26 nM
O=C(O)CCCOc1ccccc1-c1cc2ccc(C(=O)NC(c3ccccc3)c3ccccc3)cc2o1 CHEMBL152401 IC50 62.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4cncc5ccccc45)cc3CC[C@@H]12 CHEMBL340961 IC50 63.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(O)cc3)CCC12 CHEMBL324687 IC50 74.0 nM
C[C@]12C=CC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC12CC3CC(CC(C3)C1)C2 CHEMBL3706584 Ki 74.0 nM
O=C(O)Cc1ccc(C=C2CCN(C(=O)C(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL323856 IC50 75.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N(Cc1ccccc1)Cc1ccccc1 CHEMBL436215 Ki 75.0 nM
CC1=C2CCc3cc(-c4cccs4)ccc3N2CCC1=O CHEMBL327042 IC50 79.0 nM
CN1C(=O)CCC2c3ccc(I)cc3CCC21 CHEMBL439910 Log 1/IC50 79.43 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C)C4=C(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL77144 Ki 82.0 nM
CC1=C2CCc3cc(OCc4ccc(C(F)(F)F)cc4)ccc3N2CCC1=O CHEMBL119138 Log IC50 83.18 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N1CCCCC1 CHEMBL77129 Ki 85.0 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(C)(C)C)[C@@]2(C)CCC(=O)C=C12 CHEMBL312143 Ki 87.0 nM
CN1C(=O)CCC2c3ccc(C(F)(F)F)cc3CCC21 CHEMBL439908 Log 1/IC50 89.13 nM
CC1=C2CCc3cc(OCc4ccc(Cl)cc4)ccc3N2CCC1=O CHEMBL116830 IC50 92.9 nM
CC1=C2CCc3cc(OCc4cccc(Cl)c4)ccc3N2CCC1=O CHEMBL118943 IC50 93.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(F)cc4)ccc3N2CCC1=O CHEMBL180235 IC50 93.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(N)c3)CCC12 CHEMBL109088 IC50 94.0 nM
CC1=C2CCc3cc(C(=O)OCc4ccccc4)ccc3N2CCC1=O CHEMBL118416 IC50 96.8 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(Br)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL307181 Ki 97.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C)cc4)ccc3N2CCC1=O CHEMBL120923 IC50 102.0 nM
CN1CC(c2ccc(/C=C/c3ccccc3)cc2)CCC1=O CHEMBL56518 IC50 107.0 nM
CC1=C2CCc3cc(OCc4ccccc4)ccc3N2CCC1=O CHEMBL118605 IC50 111.0 nM
CC(C)Cc1ccc(C(C)Oc2ccc(C(=O)N3CC(CCCC(=O)O)c4ccccc43)cc2)cc1 CHEMBL35717 Potency 113.0 nM
CN1C(=O)CCC2(C)c3ccc(F)cc3CCC12 CHEMBL16027 Log 1/IC50 114.82 nM
COc1ccc2c(c1)CCC1C2CCC(=O)N1C CHEMBL16330 Log 1/IC50 114.82 nM
COc1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL182787 IC50 116.0 nM
COC(=O)c1ccc2c(c1)CCC1=C(C)C(=O)CCN12 CHEMBL118390 IC50 117.0 nM
COc1ccc2c(c1)CC[C@@H]1[C@@H]2CCC(=O)N1C CHEMBL335919 IC50 120.0 nM
CN1C(=O)CCC2(C)C1=CCc1cc(Cl)ccc12 CHEMBL135014 IC50 120.0 nM
COc1cccc2c1CC[C@H]1C(=[N+]=[N-])C(=O)CC[C@]21C CHEMBL167774 Ki app 120.0 nM
CN1C(=O)CC[C@@]2(C)C1=CCc1cc(Cl)ccc12 CHEMBL30223 IC50 120.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(N)cc3)CCC12 CHEMBL432977 IC50 120.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)n1ccc2ccccc21 CHEMBL24465 IC50 120.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)n3ccc4ccccc43)CCC12 CHEMBL321867 IC50 120.2 nM
COC(=O)c1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL122359 Log IC50 120.23 nM
CC(C)(C)NC(=O)[C@@H]1CCC2C3CCC4=CC(=O)CCN4C3=CC[C@@]21C CHEMBL99615 IC50 127.0 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2C3=C(CC[C@]12C)N1CCC(=O)C=C1CC3 CHEMBL1201841 IC50 127.0 nM
CC1=C2CCc3cc(-c4ccccc4)ccc3N2CCC1=O CHEMBL119361 IC50 128.0 nM
COc1ccc(C(NC(=O)c2ccc3cc(-c4ccccc4OCCCC(=O)O)oc3c2)c2ccc(OC)cc2)cc1 CHEMBL155094 IC50 130.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3N)CCC12 CHEMBL108612 IC50 130.0 nM
CC1=C2CCc3cc(-c4ccco4)ccc3N2CCC1=O CHEMBL118822 Log IC50 131.83 nM
CC(C)CCCC(C)[C@H]1CCC2C3C(CC[C@@]21C)[C@@]1(C)CCC(=O)N(C)C1C[C@@H]3c1ccccc1 CHEMBL280387 IC50 134.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)N(C)C1C[C@@H]3c1ccccc1 CHEMBL339912 IC50 134.0 nM
Cc1ccc2c(c1)CCC1[C@H](C)C(=O)C=CN21 CHEMBL332407 IC50 137.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccccc4F)ccc3N2CCC1=O CHEMBL425878 IC50 138.0 nM
CC1C(=O)C=CN2c3ccc(Cl)cc3CCC12 CHEMBL125899 IC50 141.0 nM
CC1=C2CCc3cc(OCc4ccc(C(F)(F)F)cc4C(F)(F)F)ccc3N2CCC1=O CHEMBL118452 Log IC50 147.91 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C(F)(F)F)cc4)ccc3N2CCC1=O CHEMBL183448 IC50 149.0 nM
COC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL297524 Ki 150.0 nM
CN1C(=O)CCC2=C1CCc1cc(F)ccc12 CHEMBL16152 Log 1/IC50 151.36 nM
O=C(O)c1ccc2c(c1)CCc1cc(/C=C/c3ccccc3)ccc1-2 CHEMBL55402 IC50 152.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)N3CCCc4ccccc43)CCC12 CHEMBL327098 IC50 154.0 nM
CC1=C2CCc3cc(C(=O)Oc4cccc(F)c4)ccc3N2CCC1=O CHEMBL183185 IC50 160.0 nM
CC1=C2CCc3cc(-c4cccnc4)ccc3N2CCC1=O CHEMBL118255 Log IC50 169.82 nM
Cc1ccc2c(c1)CCC1CC(=O)C=CN21 CHEMBL419602 IC50 176.0 nM
COc1ccc2c(c1)CCC1=C(C)C(=O)CCN12 CHEMBL118091 IC50 178.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76892 Ki 180.0 nM
CN1C(=S)CC[C@]2(C)c3ccc(Cl)cc3CC[C@@H]12 CHEMBL56581 IC50 183.0 nM
CC1=C2CCc3ccccc3N2CCC1=O CHEMBL118447 IC50 185.0 nM
C[C@]12CCC3C(CNC4=CC(=O)CC[C@@]43C)C1CCC2C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL323996 IC50 186.0 nM
C[C@@H]1C[C@H]2CC(=O)C=CN2c2ccc(Cl)cc21 CHEMBL331253 IC50 188.0 nM
C[C@@H]1CC2CC(=O)C=CN2c2ccc(Cl)cc21 CHEMBL116604 IC50 188.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL137691 Ki 190.0 nM
CC1=C2CCc3cc(OCc4ccccc4Cl)ccc3N2CCC1=O CHEMBL441471 IC50 194.0 nM
CC1CC(=O)C=C2CCc3cc(Cl)ccc3N21 CHEMBL125443 IC50 204.0 nM
CCOc1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL182391 IC50 209.0 nM
CCOC(=O)c1ccc2c(c1)CCC1=C(C)C(=O)CCN12 CHEMBL118389 Log IC50 218.78 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C(=O)NC(C)(C)C)cc4)ccc3N2CCC1=O CHEMBL183395 IC50 225.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1ccccc1 CHEMBL280155 Ki 240.0 nM
C[C@]12CC=C3[C@@H](CCC4=CC(=O)CCN43)C1CCC2=O CHEMBL1237306 IC50 263.0 nM
CCCNC(=O)c1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL182945 IC50 268.0 nM
CC1=C2CCc3cc(C(=O)Oc4cccc(C(F)(F)F)c4)ccc3N2CCC1=O CHEMBL183820 IC50 271.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(N)cc4)ccc3N2CCC1=O CHEMBL183500 IC50 272.0 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@]2(C)C=CC(=O)C=C12 CHEMBL308107 Ki 280.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(C)C(=O)C=C[C@]4(C)C3CC[C@@]21C CHEMBL3706585 Ki 280.0 nM
CC(C)c1cc(C(C)C)c(C(=O)[C@H]2CCC3C4CNC5=CC(=O)CC[C@]5(C)C4CC[C@@]32C)c(C(C)C)c1 CHEMBL77124 Ki 280.0 nM
O=C1C=C2CCc3ccccc3N2CC1 CHEMBL96006 Log IC50 295.12 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CCN43)[C@@H]1CCC2=O CHEMBL274238 IC50 299.0 nM
CN1CC(c2ccc(/N=N/c3ccccc3)cc2)CCC1=O CHEMBL56908 IC50 302.0 nM
O=C(O)CCCOc1ccccc1-c1cc2cc(C(=O)NC(c3ccccc3)c3ccccc3)ccc2o1 CHEMBL155568 IC50 310.0 nM
Cc1ccc2c(c1)CCC1C(C)C(=O)C=CN21 CHEMBL125769 IC50 312.0 nM
O=C(O)c1ccc2c(c1)CCc1ccccc1-2 CHEMBL341625 Ki app 315.0 nM
CN1C(=O)CC[C@@H]2c3ccc(F)cc3CC[C@@H]21 CHEMBL131803 IC50 320.0 nM
O=C(O)c1ccc2c(c1)CCc1cc(Cl)ccc1-2 CHEMBL356780 Ki app 320.0 nM
CCCN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(c2ccccc2)c2ccccc2)[C@@]2(C)C=CC(=O)C=C12 CHEMBL309585 Ki 340.0 nM
C[C@H]1Cc2cc(Cl)ccc2N2CCC(=O)C=C12 CHEMBL119255 IC50 346.0 nM
CN(C(=O)[C@H]1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@@]21C)c1ccccc1 CHEMBL25072 IC50 350.0 nM
CN(C(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C)c1ccccc1 CHEMBL111407 IC50 350.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NCc1ccccc1 CHEMBL135780 Ki 360.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C(N)=O)cc4)ccc3N2CCC1=O CHEMBL362379 IC50 361.0 nM
Cc1ccc2c(c1)CCC1=CC(=O)CCN12 CHEMBL118118 IC50 376.0 nM
CN1C(=S)CC[C@@]2(C)C1=CCc1cc(Cl)ccc12 CHEMBL58989 IC50 377.0 nM
CC1=C2CCc3cc(/C=C/c4ccccc4)ccc3N2CCC1=O CHEMBL119164 IC50 380.0 nM
CC1=C2CCc3cc(OCc4cc(C(F)(F)F)ccc4C(F)(F)F)ccc3N2CCC1=O CHEMBL116432 Log IC50 389.05 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CCN43)[C@@H]1CC[C@@H]2O CHEMBL269632 IC50 409.0 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL138225 Ki app 410.0 nM
C[C@]12CCC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)Nc3ccccc3)CC[C@@H]12 CHEMBL4064645 IC50 410.0 nM
O=C1C=CN2c3ccc(Cl)cc3CC[C@H]2C1 CHEMBL118100 IC50 459.0 nM
O=C1C=CN2c3ccc(Cl)cc3CCC2C1 CHEMBL125599 IC50 459.0 nM
O=C1CCC2=C(CCc3cc(Cl)ccc32)N1 CHEMBL277664 IC50 460.0 nM
COc1cc2cc(C(=O)O)[nH]c2cc1OCc1ccccc1 CHEMBL37880 Ki app 460.0 nM
CCN(CC)C(=O)c1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL181196 IC50 463.0 nM
C=CCc1c(OC(=O)c2ccccc2)ccc2ccc(=O)oc12 CHEMBL76959 IC50 490.0 nM
COc1cc2cc(C(=O)O)n(C)c2cc1OCc1ccccc1 CHEMBL36772 Ki app 500.0 nM
CC(=O)C1CC[C@H]2[C@@H]3CC=C4C=C(c5nnn[nH]5)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3753791 IC50 547.0 nM
CN1C(=O)CC[C@@H]2c3ccccc3CC[C@H]21 CHEMBL57789 IC50 560.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C(C)(C)C)cc4)ccc3N2CCC1=O CHEMBL118824 IC50 560.0 nM
CN1C(=O)CCC2c3ccccc3CCC21 CHEMBL277091 Log 1/IC50 562.34 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N1CCSCC1 CHEMBL73816 Ki 570.0 nM
CC(C)Cc1ccc([C@@H](C)Oc2ccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)cc2)cc1 CHEMBL280954 IC50 574.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)N3CCCCc4ccccc43)CCC12 CHEMBL326439 IC50 595.0 nM
O=C1CCC2=C(CCc3cc(F)ccc32)N1 CHEMBL134114 IC50 600.0 nM
CCN(C(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C)c1ccccc1 CHEMBL321923 IC50 614.0 nM
C=CCc1c(OC(=O)Nc2ccccc2)ccc2ccc(=O)oc12 CHEMBL312466 IC50 620.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(I)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76803 Ki 690.0 nM
O=C(O)c1cccc(C=C2CCN(C(=O)C(C3CCCCC3)C3CCCCC3)CC2)c1 CHEMBL114211 IC50 700.0 nM
CC(=O)Nc1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL182399 IC50 707.0 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(S)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL24464 IC50 709.0 nM
CCN(C)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL136863 Ki 720.0 nM
CC1=C2CCc3cc(C(=O)OC(C)C)ccc3N2CCC1=O CHEMBL119722 Log IC50 724.44 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76648 Ki 750.0 nM
C[C@]12CCC(=O)C=C1CCC1C2CC[C@]2(C)C(n3cnc4ccccc43)=CCC12 CHEMBL77789 IC50 770.0 nM
C=CCc1c(OC(C)=O)ccc2ccc(=O)oc12 CHEMBL77169 IC50 820.0 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76192 Ki app 820.0 nM
CCC(CC)(c1ccc(OC(=O)N(Cc2ccccc2)Cc2ccccc2)cc1)c1ccc(N(C)C(C)=O)cc1 CHEMBL248682 IC50 840.0 nM
C/C(CC1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C)=N\O CHEMBL137040 IC50 900.0 nM
C/C(CC1CCC2C3CC(=O)C4=CC(=O)CCC4(C)C3CCC12C)=N\O CHEMBL136097 IC50 900.0 nM
CC1=C2NCc3cc(Cl)ccc3[C@@]2(C)CCC1=O CHEMBL97266 Ki 920.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccccc4)ccc3N2CCC1=O CHEMBL118283 Log IC50 933.25 nM
COC(=O)c1cccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)c1 CHEMBL116370 Log IC50 954.99 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(Br)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL283564 IC50 981.0 nM
C=CCc1c(O)ccc2ccc(=O)oc12 CHEMBL77650 IC50 990.0 nM
CN1C(=O)CCC2(C)c3ccccc3CCC12 CHEMBL278049 Log 1/IC50 1000.0 nM
CN1C(=O)CCC2=C1CCc1ccccc12 CHEMBL16248 Log 1/IC50 1000.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CCNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL78161 Ki 1000.0 nM
CC1=C2CCc3cc(C(=O)OC(C)(C)C)ccc3N2CCC1=O CHEMBL333684 IC50 1000.0 nM
CC1=C2CCc3cc(C(=O)Nc4ccc(C)cc4)ccc3N2CCC1=O CHEMBL183692 IC50 1000.0 nM